TreeWAS – Variant ID: rs72662233

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S80.9 Superficial injury of lower leg, unspecified	0.129	0.871	0.000
S80 Superficial injury of lower leg	0.126	0.874	0.000
O20.0 Threatened abortion	0.000	0.880	0.120
S81 Open wound of lower leg	0.118	0.882	0.000
S81.0 Open wound of knee	0.117	0.883	0.000
S80-S89 Injuries to the knee and lower leg	0.117	0.883	0.000
S81.9 Open wound of lower leg, part unspecified	0.109	0.891	0.000
S80.0 Contusion of knee	0.108	0.892	0.000
S80.8 Other superficial injuries of lower leg	0.105	0.895	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.095	0.905	0.000
S86 Injury of muscle and tendon at lower leg level	0.092	0.908	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.084	0.916	0.000
S88 Traumatic amputation of lower leg	0.084	0.916	0.000
S87 Crushing injury of lower leg	0.084	0.916	0.000
S85 Injury of blood vessels at lower leg level	0.084	0.916	0.000
S84 Injury of nerves at lower leg level	0.084	0.916	0.000
S89 Other and unspecified injuries of lower leg	0.082	0.918	0.000
S80.7 Multiple superficial injuries of lower leg	0.078	0.922	0.000
S82 Fracture of lower leg, including ankle	0.078	0.922	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.076	0.924	0.000
S81.8 Open wound of other parts of lower leg	0.073	0.927	0.000
S81.7 Multiple open wounds of lower leg	0.073	0.927	0.000
O20 Haemorrhage in early pregnancy	0.000	0.930	0.070
S83.6 Sprain and strain of other and unspecified parts of knee	0.069	0.931	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.068	0.932	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.066	0.934	0.000
S86.0 Injury of Achilles tendon	0.066	0.934	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.066	0.934	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.066	0.934	0.000
S82.5 Fracture of medial malleolus	0.066	0.934	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.065	0.935	0.000
S89.8 Other specified injuries of lower leg	0.064	0.936	0.000
S83.1 Dislocation of knee	0.064	0.936	0.000
S82.4 Fracture of fibula alone	0.063	0.937	0.000
S82.0 Fracture of patella	0.062	0.938	0.000
S82.1 Fracture of upper end of tibia	0.061	0.939	0.000
S83.0 Dislocation of patella	0.061	0.939	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.060	0.939	0.000
S84.8 Injury of other nerves at lower leg level	0.060	0.939	0.000
S84.7 Injury of multiple nerves at lower leg level	0.060	0.939	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.060	0.939	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.060	0.939	0.000
S84.0 Injury of tibial nerve at lower leg level	0.060	0.939	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.060	0.939	0.000
S85.8 Injury of other blood vessels at lower leg level	0.060	0.939	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.060	0.939	0.000
S85.5 Injury of popliteal vein	0.060	0.939	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.060	0.939	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.060	0.939	0.000
S85.2 Injury of peroneal artery	0.060	0.939	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.060	0.939	0.000
S85.0 Injury of popliteal artery	0.060	0.939	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.060	0.939	0.000
S87.0 Crushing injury of knee	0.060	0.939	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.060	0.939	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.060	0.939	0.000
S88.0 Traumatic amputation at knee level	0.060	0.939	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.059	0.941	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.059	0.941	0.000
S89.7 Multiple injuries of lower leg	0.059	0.941	0.000
S89.1 Other specified injuries of lower leg	0.059	0.941	0.000
S89.0 Multiple injuries of lower leg	0.059	0.941	0.000
S82.50 Fracture of medial malleolus (closed)	0.058	0.942	0.000
S82.9 Fracture of lower leg, part unspecified	0.057	0.942	0.000
S82.7 Multiple fractures of lower leg	0.057	0.943	0.000
S83.3 Tear of articular cartilage of knee, current	0.057	0.943	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.944	0.055
S83.7 Injury to multiple structures of knee	0.055	0.945	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.946	0.054
S82.40 Fracture of fibula alone (closed)	0.052	0.948	0.000
S82.6 Fracture of lateral malleolus	0.051	0.949	0.000
S83.2 Tear of meniscus, current	0.050	0.950	0.000
S89.9 Unspecified injury of lower leg	0.049	0.951	0.000
S82.00 Fracture of patella (closed)	0.049	0.951	0.000
S82.11 Fracture of upper end of tibia (open)	0.048	0.952	0.000
S86.00 Unspecified injury of Achilles tendon	0.047	0.952	0.000
S82.3 Fracture of lower end of tibia	0.047	0.953	0.000
S82.01 Fracture of patella (open)	0.046	0.954	0.000
S82.10 Fracture of upper end of tibia (closed)	0.045	0.955	0.000
S82.41 Fracture of fibula alone (open)	0.045	0.955	0.000
S82.51 Fracture of medial malleolus (open)	0.045	0.955	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.044	0.955	0.000
S82.61 Fracture of lateral malleolus (open)	0.042	0.958	0.000
S82.70 Multiple fractures of lower leg (closed)	0.042	0.958	0.000
S82.2 Fracture of shaft of tibia	0.041	0.959	0.000
S82.71 Multiple fractures of lower leg (open)	0.041	0.959	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.040	0.960	0.000
S82.31 Fracture of lower end of tibia (open)	0.035	0.965	0.000
S82.8 Fractures of other parts of lower leg	0.030	0.970	0.000
S82.20 Fracture of shaft of tibia (closed)	0.026	0.974	0.000
S82.21 Fracture of shaft of tibia (open)	0.022	0.978	0.000
S82.86 Maisonneuve's fracture	0.021	0.978	0.000
S82.30 Fracture of lower end of tibia (closed)	0.022	0.978	0.000
S82.60 Fracture of lateral malleolus (closed)	0.018	0.982	0.000
E04.2 Non-toxic multinodular goitre	0.018	0.982	0.000
N81.2 Incomplete uterovaginal prolapse	0.000	0.983	0.017
E83.3 Disorders of phosphorus metabolism	0.000	0.984	0.016
S82.80 Fractures of other parts of lower leg (closed)	0.014	0.986	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.987	0.013
S82.81 Fractures of other parts of lower leg (open)	0.012	0.988	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.989	0.011
S02.4 Fracture of malar and maxillary bones	0.000	0.989	0.011
S02.2 Fracture of nasal bones	0.000	0.989	0.011
G91.9 Hydrocephalus, unspecified	0.011	0.989	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.990	0.010
S02 Fracture of skull and facial bones	0.000	0.990	0.010
S02.8 Fractures of other skull and facial bones	0.000	0.991	0.009
S02.3 Fracture of orbital floor	0.000	0.991	0.009
O21 Excessive vomiting in pregnancy	0.000	0.991	0.009
S02.7 Multiple fractures involving skull and facial bones	0.000	0.991	0.009
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.991	0.008
S02.30 Fracture of orbital floor (closed)	0.000	0.992	0.008
E10.5 With peripheral circulatory complications	0.008	0.992	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.992	0.008
O21.9 Vomiting of pregnancy, unspecified	0.000	0.992	0.008
S02.21 Fracture of nasal bones (open)	0.000	0.992	0.008
O22 Venous complications in pregnancy	0.000	0.992	0.008
O21.2 Late vomiting of pregnancy	0.000	0.992	0.008
G91 Hydrocephalus	0.008	0.992	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.992	0.008
E10.0 With coma	0.008	0.992	0.000
S02.6 Fracture of mandible	0.000	0.992	0.008
E10.2 With renal complications	0.008	0.992	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.992	0.008
O25 Malnutrition in pregnancy	0.000	0.992	0.008
E10 Insulin-dependent diabetes mellitus	0.008	0.992	0.000
E05.9 Thyrotoxicosis, unspecified	0.008	0.992	0.000
S02.1 Fracture of base of skull	0.000	0.993	0.007
G91.1 Obstructive hydrocephalus	0.007	0.993	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.993	0.007
O21.8 Other vomiting complicating pregnancy	0.000	0.993	0.007
S02.81 Fractures of other skull and facial bones (open)	0.000	0.993	0.007
S02.31 Fracture of orbital floor (open)	0.000	0.993	0.007
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.993	0.006
G91.8 Other hydrocephalus	0.007	0.993	0.000
G91.0 Communicating hydrocephalus	0.007	0.993	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.993	0.006
O43.8 Other placental disorders	0.006	0.994	0.000
E10.8 With unspecified complications	0.006	0.994	0.000
G91.2 Normal-pressure hydrocephalus	0.006	0.994	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.994	0.006
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.994	0.006
O22.9 Venous complication in pregnancy, unspecified	0.000	0.994	0.006
O22.8 Other venous complications in pregnancy	0.000	0.994	0.006
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.994	0.006
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.994	0.006
O22.1 Genital varices in pregnancy	0.000	0.994	0.006
S02.60 Fracture of mandible (closed)	0.000	0.994	0.006
E10.7 With multiple complications	0.006	0.994	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.006	0.994	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.006	0.994	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.994	0.006
E10.4 With neurological complications	0.006	0.994	0.000
S02.61 Fracture of mandible (open)	0.000	0.994	0.006
N20.1 Calculus of ureter	0.006	0.994	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.994	0.006
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.6 Failed or difficult intubation during pregnancy	0.000	0.994	0.006
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.994	0.006
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.994	0.006
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.994	0.006
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.994	0.006
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.994	0.006
O26.8 Other specified pregnancy-related conditions	0.000	0.994	0.006
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.994	0.006
S02.5 Fracture of tooth	0.000	0.994	0.006
G70.0 Myasthenia gravis	0.006	0.994	0.000
E10.6 With other specified complications	0.006	0.994	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.994	0.006
N20.0 Calculus of kidney	0.006	0.994	0.000
S02.0 Fracture of vault of skull	0.000	0.994	0.005
E83 Disorders of mineral metabolism	0.000	0.994	0.006
E05.8 Other thyrotoxicosis	0.005	0.994	0.000
N20 Calculus of kidney and ureter	0.005	0.995	0.000
S02.11 Fracture of base of skull (open)	0.000	0.995	0.005
O22.4 Haemorrhoids in pregnancy	0.000	0.995	0.005
E04 Other non-toxic goitre	0.005	0.995	0.000
E10.1 With ketoacidosis	0.005	0.995	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.995	0.005
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.995	0.005
K10.8 Other specified diseases of jaws	0.000	0.995	0.005
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.995	0.005
E83.4 Disorders of magnesium metabolism	0.000	0.995	0.005
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.995	0.005
N20.2 Calculus of kidney with calculus of ureter	0.005	0.995	0.000
E05.5 Thyroid crisis or storm	0.004	0.995	0.000
E05.4 Thyrotoxicosis factitia	0.004	0.995	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.004	0.995	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.004	0.995	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.995	0.004
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.995	0.004
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.995	0.004
N20.9 Urinary calculus, unspecified	0.005	0.995	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.995	0.004
K26.3 Acute without haemorrhage or perforation	0.005	0.995	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.004
E00-E07 Disorders of thyroid gland	0.004	0.996	0.000
S02.51 Fracture of tooth (open)	0.000	0.996	0.004
O26.4 Herpes gestationis	0.000	0.996	0.004
O26.1 Low weight gain in pregnancy	0.000	0.996	0.004
E83.5 Disorders of calcium metabolism	0.000	0.996	0.004
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.996	0.004
O26.5 Maternal hypotension syndrome	0.000	0.996	0.004
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.996	0.004
E83.8 Other disorders of mineral metabolism	0.000	0.996	0.004
E83.2 Disorders of zinc metabolism	0.000	0.996	0.004
E83.0 Disorders of copper metabolism	0.000	0.996	0.004
A63.0 Anogenital (venereal) warts	0.000	0.996	0.004
O47.0 False labour before 37 completed weeks of gestation	0.000	0.996	0.004
F01.9 Vascular dementia, unspecified	0.004	0.996	0.000
E04.8 Other specified non-toxic goitre	0.004	0.996	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.996	0.004
O23.2 Infections of urethra in pregnancy	0.000	0.996	0.004
O23.1 Infections of bladder in pregnancy	0.000	0.996	0.004
O26.0 Excessive weight gain in pregnancy	0.000	0.996	0.004
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.996	0.004
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.996	0.004
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.996	0.004
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.996	0.004
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.996	0.004
O21.0 Mild hyperemesis gravidarum	0.000	0.996	0.004
O26.2 Pregnancy care of habitual aborter	0.000	0.996	0.004
O23.0 Infections of kidney in pregnancy	0.000	0.996	0.003
N81.3 Complete uterovaginal prolapse	0.000	0.996	0.004
E10.3 With ophthalmic complications	0.004	0.996	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.996	0.003
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.996	0.003
S02.01 Fracture of vault of skull (open)	0.000	0.997	0.003
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.997	0.003
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.997	0.003
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.003
E07 Other disorders of thyroid	0.003	0.997	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.997	0.003
E03 Other hypothyroidism	0.003	0.997	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.997	0.003
M40.24 Other and unspecified kyphosis (Thoracic region)	0.003	0.997	0.000
H16.0 Corneal ulcer	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.997	0.003
E03.8 Other specified hypothyroidism	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M79.66 Pain in limb (Lower leg)	0.003	0.997	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.003	0.997	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.997	0.002
G70 Myasthenia gravis and other myoneural disorders	0.003	0.997	0.000
H47.1 Papilloedema, unspecified	0.000	0.997	0.003
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.997	0.003
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.003	0.997	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.003	0.997	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.003	0.997	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.003	0.997	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.003	0.997	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.003	0.997	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.003	0.997	0.000
K14.8 Other diseases of tongue	0.000	0.997	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.997	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.000	0.997	0.003
H92.0 Otalgia	0.003	0.997	0.000
E07.1 Dyshormogenetic goitre	0.003	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.997	0.000
E03.1 Congenital hypothyroidism without goitre	0.003	0.997	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.003	0.997	0.000
E03.5 Myxoedema coma	0.003	0.997	0.000
E03.4 Atrophy of thyroid (acquired)	0.003	0.997	0.000
E03.3 Postinfectious hypothyroidism	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.997	0.002
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.997	0.003
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.997	0.003
E06.4 Drug-induced thyroiditis	0.002	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.997	0.000
E06.0 Acute thyroiditis	0.002	0.997	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.000	0.997	0.002
E06.9 Thyroiditis, unspecified	0.002	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.997	0.000
E06.1 Subacute thyroiditis	0.002	0.997	0.000
F01 Vascular dementia	0.002	0.997	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
M40.2 Other and unspecified kyphosis	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
G70.2 Congenital and developmental myasthenia	0.002	0.998	0.000
G70.1 Toxic myoneural disorders	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
R57.2 Septic shock	0.000	0.998	0.002
M79.19 Myalgia (Site unspecified)	0.002	0.998	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
M40.29 Other and unspecified kyphosis (Site unspecified)	0.002	0.998	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.998	0.002
H33.2 Serous retinal detachment	0.000	0.998	0.002
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
D33.3 Cranial nerves	0.000	0.998	0.002
N30.9 Cystitis, unspecified	0.002	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.998	0.002
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
K10 Other diseases of jaws	0.000	0.998	0.002
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.002	0.998	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.002	0.998	0.000
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.002	0.998	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.002	0.998	0.000
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.002	0.998	0.000
R26.3 Immobility	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.002	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
O43 Placental disorders	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.000	0.998	0.002
E13.9 Without complications	0.002	0.998	0.000
K10.0 Developmental disorders of jaws	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
G12.2 Motor neuron disease	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
S36.8 Injury of other intra-abdominal organs	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.998	0.002
E10.9 Without complications	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.002	0.998	0.000
N30.3 Trigonitis	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
K10.1 Giant cell granuloma, central	0.000	0.998	0.002
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
K10.9 Disease of jaws, unspecified	0.000	0.998	0.002
K10.3 Alveolitis of jaws	0.000	0.998	0.002
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.998	0.002
H47.2 Optic atrophy	0.000	0.998	0.002
T92 Sequelae of injuries of upper limb	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.002
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.002	0.998	0.000
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.000	0.998	0.002
S27.3 Other injuries of lung	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
S36.0 Injury of spleen	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.998	0.002
D10.1 Tongue	0.000	0.998	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.001	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.001	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.001	0.998	0.000
S36.6 Injury of rectum	0.001	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.002	0.998	0.000
E13.8 With unspecified complications	0.001	0.998	0.000
E13.7 With multiple complications	0.001	0.998	0.000
E13.6 With other specified complications	0.001	0.998	0.000
E13.5 With peripheral circulatory complications	0.001	0.998	0.000
E13.4 With neurological complications	0.001	0.998	0.000
E13.2 With renal complications	0.001	0.998	0.000
E13.1 With ketoacidosis	0.001	0.998	0.000
E13.0 With coma	0.001	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.998	0.000
H16.2 Keratoconjunctivitis	0.001	0.998	0.000
O43.1 Malformation of placenta	0.001	0.998	0.000
G71.1 Myotonic disorders	0.001	0.998	0.000
H16.8 Other keratitis	0.001	0.998	0.000
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
T81.8 Other complications of procedures, not elsewhere classified	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.000	0.998	0.001
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.001
O43.9 Placental disorder, unspecified	0.001	0.998	0.000
H16.4 Corneal neovascularisation	0.001	0.999	0.000
R26.1 Paralytic gait	0.000	0.999	0.001
S27 Injury of other and unspecified intrathoracic organs	0.001	0.999	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.001	0.999	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.999	0.001
F05 Delirium, not induced by alcohol and other psychoactive substances	0.001	0.999	0.000
F02.3 Dementia in Parkinson's disease	0.001	0.999	0.000
S36.4 Injury of small intestine	0.001	0.999	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.001	0.999	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.001	0.999	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.999	0.001
T92.1 Sequelae of fracture of arm	0.000	0.999	0.001
O47 False labour	0.000	0.999	0.001
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.001	0.999	0.000
S36.7 Injury of multiple intra-abdominal organs	0.001	0.999	0.000
S36.5 Injury of colon	0.001	0.999	0.000
S36.3 Injury of stomach	0.001	0.999	0.000
S36.2 Injury of pancreas	0.001	0.999	0.000
S36.1 Injury of liver or gallbladder	0.001	0.999	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.999	0.000
T92.0 Sequelae of open wound of upper limb	0.000	0.999	0.001
S36.61 Injury of rectum (with open wound into cavity)	0.001	0.999	0.000
A05.9 Bacterial foodborne intoxication, unspecified	0.001	0.999	0.000
E12 Malnutrition-related diabetes mellitus	0.001	0.999	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.000	0.999	0.001
F05.1 Delirium superimposed on dementia	0.001	0.999	0.000
K10.2 Inflammatory conditions of jaws	0.000	0.999	0.001
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.999	0.000
M89.84 Other specified disorders of bone (Hand)	0.001	0.999	0.000
F07.0 Organic personality disorder	0.001	0.999	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.999	0.001
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.999	0.001
S31.4 Open wound of vagina and vulva	0.001	0.999	0.000
F02 Dementia in other diseases classified elsewhere	0.001	0.999	0.000
S27.8 Injury of other specified intrathoracic organs	0.001	0.999	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.001	0.999	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.001	0.999	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.001	0.999	0.000
H18.1 Bullous keratopathy	0.001	0.999	0.000
M89.8 Other specified disorders of bone	0.001	0.999	0.000
S27.9 Injury of unspecified intrathoracic organ	0.001	0.999	0.000
S27.7 Multiple injuries of intrathoracic organs	0.001	0.999	0.000
S27.6 Injury of pleura	0.001	0.999	0.000
S27.5 Injury of thoracic trachea	0.001	0.999	0.000
S27.4 Injury of bronchus	0.001	0.999	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.999	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.001	0.999	0.000
I74 Arterial embolism and thrombosis	0.000	0.999	0.001
M07.38 Other psoriatic arthropathies (Other)	0.001	0.999	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.999	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.999	0.001
M89.88 Other specified disorders of bone (Other)	0.001	0.999	0.000
M89.83 Other specified disorders of bone (Forearm)	0.001	0.999	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.1 Postencephalitic syndrome	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.001	0.999	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.001	0.999	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.001	0.999	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.001	0.999	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.001	0.999	0.000
S36.51 Injury of colon (with open wound into cavity)	0.001	0.999	0.000
S36.50 Injury of colon (without open wound into cavity)	0.001	0.999	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.001	0.999	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.001	0.999	0.000
K92.0 Haematemesis	0.000	0.999	0.001
O47.9 False labour, unspecified	0.000	0.999	0.001
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000
M54.50 Low back pain (Multiple sites in spine)	0.001	0.999	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.001	0.999	0.000
E12.9 Without complications	0.001	0.999	0.000
E12.8 With unspecified complications	0.001	0.999	0.000
E12.7 With multiple complications	0.001	0.999	0.000
E12.6 With other specified complications	0.001	0.999	0.000
E12.5 With peripheral circulatory complications	0.001	0.999	0.000
E12.4 With neurological complications	0.001	0.999	0.000
E12.3 With ophthalmic complications	0.001	0.999	0.000
E12.2 With renal complications	0.001	0.999	0.000
E12.1 With ketoacidosis	0.001	0.999	0.000
E12.0 With coma	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.001	0.999	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
M25.74 Osteophyte (Hand)	0.000	0.999	0.001
D04.7 Skin of lower limb, including hip	0.001	0.999	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.999	0.000
F02.2 Dementia in Huntington's disease	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations