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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72677908
log Bayes Factor = 12.809
Chromosome 1   position 62,462,325  (GRCh37) Explore rs72677908 on Ensembl!
Variant rs72677908 is part of Cluster X0064

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
I50 Heart failure
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
I25.2 Old myocardial infarction
0.989 0.011 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.987 0.013 0.000
I44 Atrioventricular and left bundle-branch block
0.981 0.019 0.000
I25.1 Atherosclerotic heart disease
0.979 0.021 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.967 0.033 0.000
I50.1 Left ventricular failure
0.967 0.033 0.000
J40-J47 Chronic lower respiratory diseases
0.962 0.038 0.000
I49 Other cardiac arrhythmias
0.960 0.040 0.000
I34 Nonrheumatic mitral valve disorders
0.956 0.044 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
Y95 Nosocomial condition
0.950 0.050 0.000
J95-J99 Other diseases of the respiratory system
0.950 0.050 0.000
I05-I09 Chronic rheumatic heart diseases
0.938 0.062 0.000
I44.0 Atrioventricular block, first degree
0.937 0.063 0.000
I21 Acute myocardial infarction
0.933 0.067 0.000
J30-J39 Other diseases of upper respiratory tract
0.929 0.071 0.000
J45 Asthma
0.924 0.076 0.000
J98 Other respiratory disorders
0.923 0.077 0.000
Chapter V Mental and behavioural disorders
0.922 0.078 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.919 0.081 0.000
I34.0 Mitral (valve) insufficiency
0.919 0.081 0.000
I50.9 Heart failure, unspecified
0.909 0.091 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.895 0.105 0.000
J44 Other chronic obstructive pulmonary disease
0.891 0.109 0.000
J60-J70 Lung diseases due to external agents
0.888 0.112 0.000
I24 Other acute ischaemic heart diseases
0.887 0.113 0.000
J00-J06 Acute upper respiratory infections
0.875 0.124 0.000
Chapter VIII Diseases of the ear and mastoid process
0.875 0.125 0.000
I50.0 Congestive heart failure
0.871 0.129 0.000
J32 Chronic sinusitis
0.869 0.131 0.000
I21.4 Acute subendocardial myocardial infarction
0.867 0.133 0.000
I42 Cardiomyopathy
0.861 0.139 0.000
I51 Complications and ill-defined descriptions of heart disease
0.861 0.139 0.000
J45.0 Predominantly allergic asthma
0.861 0.139 0.000
I44.2 Atrioventricular block, complete
0.856 0.144 0.000
I60-I69 Cerebrovascular diseases
0.856 0.144 0.000
I27 Other pulmonary heart diseases
0.853 0.147 0.000
I49.5 Sick sinus syndrome
0.847 0.153 0.000
I25.5 Ischaemic cardiomyopathy
0.847 0.153 0.000
I08 Multiple valve diseases
0.843 0.157 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.840 0.160 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.837 0.163 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.834 0.166 0.000
J98.1 Pulmonary collapse
0.830 0.170 0.000
J90-J94 Other diseases of pleura
0.828 0.172 0.000
I49.3 Ventricular premature depolarisation
0.827 0.173 0.000
J98.4 Other disorders of lung
0.825 0.175 0.000
J69 Pneumonitis due to solids and liquids
0.822 0.178 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.821 0.179 0.000
I45 Other conduction disorders
0.818 0.182 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.817 0.183 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
I22 Subsequent myocardial infarction
0.815 0.185 0.000
I51.7 Cardiomegaly
0.811 0.189 0.000
J45.9 Asthma, unspecified
0.811 0.189 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.807 0.192 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.806 0.194 0.000
I46 Cardiac arrest
0.806 0.194 0.000
I49.9 Cardiac arrhythmia, unspecified
0.803 0.197 0.000
H65-H75 Diseases of middle ear and mastoid
0.800 0.200 0.000
W00-W19 Falls
0.797 0.203 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.795 0.205 0.000
J30 Vasomotor and allergic rhinitis
0.793 0.207 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.787 0.213 0.000
Y52 Agents primarily affecting the cardiovascular system
0.786 0.214 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.779 0.221 0.000
J98.8 Other specified respiratory disorders
0.778 0.222 0.000
F30-F39 Mood [affective] disorders
0.777 0.223 0.000
I44.6 Other and unspecified fascicular block
0.776 0.224 0.000
I42.0 Dilated cardiomyopathy
0.775 0.225 0.000
J69.0 Pneumonitis due to food and vomit
0.775 0.225 0.000
I44.3 Other and unspecified atrioventricular block
0.773 0.227 0.000
J32.0 Chronic maxillary sinusitis
0.772 0.228 0.000
Chapter I Certain infectious and parasitic diseases
0.769 0.231 0.000
Chapter VI Diseases of the nervous system
0.767 0.233 0.000
W50-W64 Exposure to animate mechanical forces
0.766 0.234 0.000
Y44 Agents primarily affecting blood constituents
0.764 0.236 0.000
I33 Acute and subacute endocarditis
0.764 0.236 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.764 0.236 0.000
V80-V89 Other land transport accidents
0.760 0.239 0.000
I67 Other cerebrovascular diseases
0.760 0.240 0.000
I05 Rheumatic mitral valve diseases
0.760 0.240 0.000
I25.3 Aneurysm of heart
0.756 0.244 0.000
J03 Acute tonsillitis
0.756 0.244 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
J09-J18 Influenza and pneumonia
0.755 0.245 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.753 0.247 0.000
I07 Rheumatic tricuspid valve diseases
0.753 0.247 0.000
J32.9 Chronic sinusitis, unspecified
0.743 0.257 0.000
J39 Other diseases of upper respiratory tract
0.738 0.262 0.000
I49.4 Other and unspecified premature depolarisation
0.738 0.262 0.000
I30 Acute pericarditis
0.736 0.264 0.000
Y43 Primarily systemic agents
0.735 0.265 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.735 0.265 0.000
J01 Acute sinusitis
0.731 0.269 0.000
L50-L54 Urticaria and erythema
0.730 0.270 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.729 0.271 0.000
I31 Other diseases of pericardium
0.728 0.272 0.000
I27.9 Pulmonary heart disease, unspecified
0.726 0.274 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.725 0.275 0.000
V10-V19 Pedal cyclist injured in transport accident
0.724 0.276 0.000
I44.7 Left bundle-branch block, unspecified
0.722 0.278 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.722 0.278 0.000
I61 Intracerebral haemorrhage
0.722 0.278 0.000
I34.1 Mitral (valve) prolapse
0.721 0.279 0.000
J37 Chronic laryngitis and laryngotracheitis
0.721 0.279 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.719 0.281 0.000
J98.9 Respiratory disorder, unspecified
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H65 Nonsuppurative otitis media
0.716 0.284 0.000
O00-O08 Pregnancy with abortive outcome
0.714 0.286 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
I27.0 Primary pulmonary hypertension
0.707 0.293 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.706 0.294 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.705 0.295 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.705 0.295 0.000
I27.2 Other secondary pulmonary hypertension
0.704 0.296 0.000
I24.8 Other forms of acute ischaemic heart disease
0.703 0.296 0.000
I44.5 Left posterior fascicular block
0.703 0.297 0.000
I44.4 Left anterior fascicular block
0.703 0.297 0.000
F60-F69 Disorders of adult personality and behaviour
0.702 0.298 0.000
F80-F89 Disorders of psychological development
0.701 0.299 0.000
J38.7 Other diseases of larynx
0.701 0.299 0.000
F99-F99 Unspecified mental disorder
0.700 0.300 0.000
J46 Status asthmaticus
0.699 0.301 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.697 0.303 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.696 0.304 0.000
H60-H62 Diseases of external ear
0.695 0.305 0.000
L81 Other disorders of pigmentation
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.694 0.306 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.694 0.306 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.694 0.306 0.000
Y98 Lifestyle-related condition
0.694 0.306 0.000
Y97 Environmental-pollution-related condition
0.694 0.306 0.000
Y96 Work-related condition
0.694 0.306 0.000
B95-B98 Bacterial, viral and other infectious agents
0.693 0.307 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.693 0.307 0.000
Y57 Other and unspecified drugs and medicaments
0.691 0.309 0.000
I95 Hypotension
0.690 0.310 0.000
I26 Pulmonary embolism
0.690 0.310 0.000
J41 Simple and mucopurulent chronic bronchitis
0.690 0.310 0.000
I49.2 Junctional premature depolarisation
0.688 0.311 0.000
I49.1 Atrial premature depolarisation
0.688 0.311 0.000
J43 Emphysema
0.687 0.313 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.685 0.315 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.685 0.315 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.685 0.315 0.000
I62 Other nontraumatic intracranial haemorrhage
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.683 0.317 0.000
J91 Pleural effusion in conditions classified elsewhere
0.683 0.317 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.683 0.317 0.000
I49.8 Other specified cardiac arrhythmias
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.682 0.317 0.000
Y58 Bacterial vaccines
0.682 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.682 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.682 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.682 0.317 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.682 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.682 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.682 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.317 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.681 0.319 0.000
J96 Respiratory failure, not elsewhere classified
0.681 0.319 0.000
I38 Endocarditis, valve unspecified
0.681 0.319 0.000
Y86 Sequelae of other accidents
0.681 0.319 0.000
I60 Subarachnoid haemorrhage
0.679 0.320 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
I67.9 Cerebrovascular disease, unspecified
0.678 0.322 0.000
J38.4 Oedema of larynx
0.676 0.324 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.675 0.325 0.000
I09 Other rheumatic heart diseases
0.672 0.327 0.000
I06 Rheumatic aortic valve diseases
0.672 0.327 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.672 0.328 0.000
I49.0 Ventricular fibrillation and flutter
0.671 0.329 0.000
J03.9 Acute tonsillitis, unspecified
0.671 0.329 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.670 0.330 0.000
I08.0 Disorders of both mitral and aortic valves
0.670 0.330 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.669 0.331 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.669 0.331 0.000
I45.5 Other specified heart block
0.669 0.331 0.000
J47 Bronchiectasis
0.669 0.331 0.000
J36 Peritonsillar abscess
0.667 0.333 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.663 0.337 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.663 0.337 0.000
J45.8 Mixed asthma
0.662 0.338 0.000
J45.1 Nonallergic asthma
0.662 0.338 0.000
J98.6 Disorders of diaphragm
0.662 0.338 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.662 0.338 0.000
J98.3 Compensatory emphysema
0.662 0.338 0.000
J98.2 Interstitial emphysema
0.662 0.338 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.661 0.339 0.000
F70-F79 Mental retardation
0.661 0.339 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.659 0.341 0.000
I28 Other diseases of pulmonary vessels
0.659 0.341 0.000
I35 Nonrheumatic aortic valve disorders
0.656 0.344 0.000
F10.0 Acute intoxication
0.656 0.344 0.000
J90 Pleural effusion, not elsewhere classified
0.656 0.344 0.000
I46.0 Cardiac arrest with successful resuscitation
0.655 0.345 0.000
J32.8 Other chronic sinusitis
0.655 0.345 0.000
J30.1 Allergic rhinitis due to pollen
0.652 0.347 0.000
J00 Acute nasopharyngitis [common cold]
0.652 0.348 0.000
I69 Sequelae of cerebrovascular disease
0.647 0.353 0.000
X60-X84 Intentional self-harm
0.646 0.353 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.645 0.355 0.000
J38.1 Polyp of vocal cord and larynx
0.645 0.355 0.000
L90 Atrophic disorders of skin
0.645 0.355 0.000
Q60-Q64 Congenital malformations of the urinary system
0.644 0.356 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.643 0.356 0.000
L84 Corns and callosities
0.643 0.357 0.000
H65.3 Chronic mucoid otitis media
0.643 0.357 0.000
F33 Recurrent depressive disorder
0.643 0.357 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.642 0.358 0.000
L10-L14 Bullous disorders
0.641 0.358 0.000
Y40 Systemic antibiotics
0.640 0.360 0.000
I45.9 Conduction disorder, unspecified
0.640 0.360 0.000
F10.2 Dependence syndrome
0.639 0.361 0.000
Y42.5 Other oestrogens and progestogens
0.637 0.363 0.000
J70 Respiratory conditions due to other external agents
0.637 0.363 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.637 0.363 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.637 0.363 0.000
J66 Airway disease due to specific organic dust
0.637 0.363 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.637 0.363 0.000
J62 Pneumoconiosis due to dust containing silica
0.637 0.363 0.000
J65 Pneumoconiosis associated with tuberculosis
0.637 0.363 0.000
J64 Unspecified pneumoconiosis
0.637 0.363 0.000
J60 Coalworker's pneumoconiosis
0.637 0.363 0.000
J30.4 Allergic rhinitis, unspecified
0.637 0.363 0.000
I24.1 Dressler's syndrome
0.636 0.364 0.000
Y42.7 Androgens and anabolic congeners
0.635 0.365 0.000
L91 Hypertrophic disorders of skin
0.634 0.366 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.633 0.367 0.000
I05.0 Mitral stenosis
0.632 0.367 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.631 0.369 0.000
H66 Suppurative and unspecified otitis media
0.630 0.370 0.000
Y44.2 Anticoagulants
0.630 0.370 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.629 0.371 0.000
J38.2 Nodules of vocal cords
0.628 0.372 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.628 0.372 0.000
J04 Acute laryngitis and tracheitis
0.628 0.372 0.000
J01.9 Acute sinusitis, unspecified
0.628 0.372 0.000
W08 Fall involving other furniture
0.627 0.373 0.000
O60-O75 Complications of labour and delivery
0.627 0.373 0.000
Q50-Q56 Congenital malformations of genital organs
0.625 0.374 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.624 0.376 0.000
H80-H83 Diseases of inner ear
0.624 0.376 0.000
I47 Paroxysmal tachycardia
0.624 0.376 0.000
J32.4 Chronic pansinusitis
0.623 0.377 0.000
J32.3 Chronic sphenoidal sinusitis
0.623 0.377 0.000
J32.2 Chronic ethmoidal sinusitis
0.623 0.377 0.000
J32.1 Chronic frontal sinusitis
0.623 0.377 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.622 0.378 0.000
I95.1 Orthostatic hypotension
0.622 0.378 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.620 0.379 0.000
I07.1 Tricuspid insufficiency
0.620 0.380 0.000
I42.8 Other cardiomyopathies
0.618 0.382 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.618 0.382 0.000
I42.6 Alcoholic cardiomyopathy
0.618 0.382 0.000
I42.5 Other restrictive cardiomyopathy
0.618 0.382 0.000
I42.4 Endocardial fibroelastosis
0.618 0.382 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.618 0.382 0.000
I42.2 Other hypertrophic cardiomyopathy
0.618 0.382 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.618 0.382 0.000
Q00-Q07 Congenital malformations of the nervous system
0.618 0.382 0.000
I51.6 Cardiovascular disease, unspecified
0.617 0.382 0.000
I51.5 Myocardial degeneration
0.617 0.382 0.000
I51.4 Myocarditis, unspecified
0.617 0.382 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.617 0.382 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.617 0.382 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.617 0.382 0.000
I51.0 Cardiac septal defect, acquired
0.617 0.382 0.000
I45.6 Preexcitation syndrome
0.617 0.383 0.000
W19 Unspecified fall
0.617 0.383 0.000
F31 Bipolar affective disorder
0.617 0.383 0.000
I67.2 Cerebral atherosclerosis
0.616 0.383 0.000
L85 Other epidermal thickening
0.614 0.386 0.000
I44.1 Atrioventricular block, second degree
0.614 0.386 0.000
J93 Pneumothorax
0.614 0.386 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.614 0.386 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.614 0.386 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.614 0.386 0.000
I27.8 Other specified pulmonary heart diseases
0.612 0.388 0.000
I27.1 Kyphoscoliotic heart disease
0.612 0.388 0.000
Y54.3 Benzothiadiazine derivatives
0.611 0.389 0.000
J33 Nasal polyp
0.611 0.389 0.000
L53 Other erythematous conditions
0.609 0.391 0.000
B15-B19 Viral hepatitis
0.608 0.392 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.608 0.392 0.000
L03 Cellulitis
0.608 0.392 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.605 0.395 0.000
I31.3 Pericardial effusion (noninflammatory)
0.605 0.395 0.000
W20-W49 Exposure to inanimate mechanical forces
0.605 0.395 0.000
W55 Bitten or struck by other mammals
0.605 0.395 0.000
Q80-Q89 Other congenital malformations
0.605 0.395 0.000
L93 Lupus erythematosus
0.605 0.395 0.000
I08.9 Multiple valve disease, unspecified
0.604 0.396 0.000
I08.8 Other multiple valve diseases
0.604 0.396 0.000
J38.3 Other diseases of vocal cords
0.603 0.397 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.603 0.397 0.000
D75 Other diseases of blood and blood-forming organs
0.603 0.397 0.000
O85-O92 Complications predominantly related to the puerperium
0.602 0.398 0.000
O03 Spontaneous abortion
0.602 0.398 0.000
B65-B83 Helminthiases
0.602 0.398 0.000
J39.2 Other diseases of pharynx
0.601 0.399 0.000
J38.6 Stenosis of larynx
0.600 0.399 0.000
J38.5 Laryngeal spasm
0.600 0.399 0.000
J38.0 Paralysis of vocal cords and larynx
0.600 0.399 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.600 0.400 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.599 0.401 0.000
H69 Other disorders of Eustachian tube
0.599 0.401 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.598 0.402 0.000
G50 Disorders of trigeminal nerve
0.596 0.404 0.000
I46.9 Cardiac arrest, unspecified
0.596 0.404 0.000
L20-L30 Dermatitis and eczema
0.595 0.405 0.000
H74 Other disorders of middle ear and mastoid
0.595 0.405 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.595 0.405 0.000
I33.0 Acute and subacute infective endocarditis
0.595 0.405 0.000
J94 Other pleural conditions
0.593 0.406 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.592 0.408 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.591 0.409 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.590 0.410 0.000
J69.8 Pneumonitis due to other solids and liquids
0.589 0.411 0.000
J69.1 Pneumonitis due to oils and essences
0.589 0.411 0.000
I99 Other and unspecified disorders of circulatory system
0.589 0.411 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.587 0.413 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.587 0.413 0.000
I45.8 Other specified conduction disorders
0.586 0.414 0.000
I45.4 Nonspecific intraventricular block
0.586 0.414 0.000
I45.3 Trifascicular block
0.586 0.414 0.000
I45.2 Bifascicular block
0.586 0.414 0.000
I45.0 Right fascicular block
0.586 0.414 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.586 0.414 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.586 0.414 0.000
L94 Other localised connective tissue disorders
0.586 0.414 0.000
L87 Transepidermal elimination disorders
0.586 0.414 0.000
L88 Pyoderma gangrenosum
0.586 0.414 0.000
L86 Keratoderma in diseases classified elsewhere
0.586 0.414 0.000
L83 Acanthosis nigricans
0.586 0.414 0.000
L80 Vitiligo
0.586 0.414 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.586 0.414 0.000
B99-B99 Other infectious diseases
0.586 0.414 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.585 0.415 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.585 0.415 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.585 0.415 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.585 0.415 0.000
Q35-Q37 Cleft lip and cleft palate
0.585 0.415 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.585 0.415 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.585 0.415 0.000
I22.8 Subsequent myocardial infarction of other sites
0.585 0.415 0.000
Y45.0 Opioids and related analgesics
0.584 0.416 0.000
W06 Fall involving bed
0.583 0.416 0.000
L81.4 Other melanin hyperpigmentation
0.582 0.418 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.582 0.418 0.000
H71 Cholesteatoma of middle ear
0.582 0.418 0.000
I42.9 Cardiomyopathy, unspecified
0.581 0.419 0.000
O04 Medical abortion
0.581 0.419 0.000
Y43.3 Other antineoplastic drugs
0.579 0.421 0.000
R55 Syncope and collapse
0.579 0.421 0.000
D55-D59 Haemolytic anaemias
0.578 0.422 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.578 0.422 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.578 0.422 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.578 0.422 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.578 0.422 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.578 0.422 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.578 0.422 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.578 0.422 0.000
F11 Mental and behavioural disorders due to use of opioids
0.578 0.422 0.000
I46.1 Sudden cardiac death, so described
0.578 0.422 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.577 0.423 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.575 0.424 0.000
I71 Aortic aneurysm and dissection
0.574 0.426 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.573 0.426 0.000
H70 Mastoiditis and related conditions
0.573 0.426 0.000
H68 Eustachian salpingitis and obstruction
0.573 0.426 0.000
H67 Otitis media in diseases classified elsewhere
0.573 0.426 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.573 0.427 0.000
W18 Other fall on same level
0.571 0.428 0.000
W17 Other fall from one level to another
0.571 0.428 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.571 0.428 0.000
W15 Fall from cliff
0.571 0.428 0.000
W14 Fall from tree
0.571 0.428 0.000
W12 Fall on and from scaffolding
0.571 0.428 0.000
W11 Fall on and from ladder
0.571 0.428 0.000
W10 Fall on and from stairs and steps
0.571 0.428 0.000
W09 Fall involving playground equipment
0.571 0.428 0.000
W05 Fall involving wheelchair
0.571 0.428 0.000
W04 Fall while being carried or supported by other persons
0.571 0.428 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.571 0.428 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.571 0.428 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.571 0.428 0.000
W00 Fall on same level involving ice and snow
0.571 0.428 0.000
J37.0 Chronic laryngitis
0.571 0.429 0.000
R50-R69 General symptoms and signs
0.571 0.429 0.000
Y42.9 Other and unspecified hormone antagonists
0.570 0.430 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.570 0.430 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.570 0.430 0.000
Y42.4 Oral contraceptives
0.570 0.430 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.570 0.430 0.000
Y42.2 Antithyroid drugs
0.570 0.430 0.000
Y42.1 Thyroid hormones and substitutes
0.570 0.430 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.570 0.430 0.000
J30.3 Other allergic rhinitis
0.568 0.431 0.000
J30.2 Other seasonal allergic rhinitis
0.568 0.431 0.000
J30.0 Vasomotor rhinitis
0.568 0.431 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.567 0.433 0.000
W07 Fall involving chair
0.565 0.435 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.565 0.435 0.000
L08 Other local infections of skin and subcutaneous tissue
0.565 0.435 0.000
Y89 Sequelae of other external causes
0.564 0.436 0.000
Y88 Sequelae of surgical and medical care as external cause
0.564 0.436 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.564 0.436 0.000
B25-B34 Other viral diseases
0.564 0.436 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.563 0.437 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.563 0.437 0.000
Y52.7 Peripheral vasodilators
0.563 0.437 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.563 0.437 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.563 0.437 0.000
Y52.1 Calcium-channel blockers
0.563 0.437 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.563 0.437 0.000
D80-D89 Certain disorders involving the immune mechanism
0.563 0.437 0.000
H73 Other disorders of tympanic membrane
0.562 0.437 0.000
G35 Multiple sclerosis
0.563 0.437 0.000
H72 Perforation of tympanic membrane
0.562 0.438 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.561 0.439 0.000
H65.2 Chronic serous otitis media
0.561 0.439 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.561 0.439 0.000
G58 Other mononeuropathies
0.559 0.441 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.559 0.441 0.000
W13 Fall from, out of or through building or structure
0.559 0.441 0.000
F38 Other mood [affective] disorders
0.557 0.443 0.000
F34 Persistent mood [affective] disorders
0.557 0.443 0.000
F30 Manic episode
0.557 0.443 0.000
F39 Unspecified mood [affective] disorder
0.557 0.443 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.557 0.443 0.000
J42 Unspecified chronic bronchitis
0.556 0.444 0.000
O00 Ectopic pregnancy
0.555 0.445 0.000
G37 Other demyelinating diseases of central nervous system
0.554 0.446 0.000
F50 Eating disorders
0.554 0.446 0.000
G70-G73 Diseases of myoneural junction and muscle
0.553 0.446 0.000
L90.0 Lichen sclerosus et atrophicus
0.553 0.447 0.000
L60-L75 Disorders of skin appendages
0.552 0.448 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.552 0.448 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.551 0.449 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.551 0.449 0.000
B50-B64 Protozoal diseases
0.551 0.449 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.551 0.449 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.551 0.449 0.000
A80-A89 Viral infections of the central nervous system
0.551 0.449 0.000
A75-A79 Rickettsioses
0.551 0.449 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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