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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72730448
log Bayes Factor = 14.5786
Chromosome 1   position 93,533,524  (GRCh37) Explore rs72730448 on Ensembl!
Variant rs72730448 is part of Cluster X0089

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.998 0.002 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
N20-N23 Urolithiasis
0.990 0.010 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.990 0.010 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.987 0.013 0.000
Z86 Personal history of certain other diseases
0.986 0.014 0.000
N20 Calculus of kidney and ureter
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
F10.1 Harmful use
0.981 0.019 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.979 0.021 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.974 0.026 0.000
Z86.7 Personal history of diseases of the circulatory system
0.973 0.027 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.969 0.031 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.965 0.035 0.000
I30-I52 Other forms of heart disease
0.964 0.036 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.963 0.037 0.000
S60-S69 Injuries to the wrist and hand
0.963 0.037 0.000
I26 Pulmonary embolism
0.956 0.044 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.954 0.046 0.000
Z33 Pregnant state, incidental
0.953 0.047 0.000
N20.0 Calculus of kidney
0.951 0.049 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.950 0.050 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.950 0.050 0.000
N30-N39 Other diseases of urinary system
0.945 0.055 0.000
N20.1 Calculus of ureter
0.945 0.055 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.939 0.061 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.932 0.068 0.000
Z98 Other postsurgical states
0.932 0.068 0.000
E65-E68 Obesity and other hyperalimentation
0.932 0.068 0.000
I50 Heart failure
0.930 0.070 0.000
Y40 Systemic antibiotics
0.922 0.078 0.000
Z60 Problems related to social environment
0.920 0.080 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.919 0.081 0.000
F10.0 Acute intoxication
0.916 0.084 0.000
E66 Obesity
0.915 0.085 0.000
N73 Other female pelvic inflammatory diseases
0.913 0.087 0.000
F10.3 Withdrawal state
0.909 0.091 0.000
Z92 Personal history of medical treatment
0.906 0.094 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.901 0.099 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.899 0.101 0.000
Z34 Supervision of normal pregnancy
0.898 0.102 0.000
B95-B98 Bacterial, viral and other infectious agents
0.898 0.102 0.000
Chapter VII Diseases of the eye and adnexa
0.898 0.102 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.897 0.103 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.896 0.104 0.000
I50.0 Congestive heart failure
0.895 0.105 0.000
Chapter II Neoplasms
0.895 0.105 0.000
E66.9 Obesity, unspecified
0.889 0.111 0.000
Z35 Supervision of high-risk pregnancy
0.888 0.112 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.888 0.112 0.000
N73.6 Female pelvic peritoneal adhesions
0.886 0.114 0.000
I05-I09 Chronic rheumatic heart diseases
0.885 0.115 0.000
Z60.2 Living alone
0.885 0.115 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.885 0.115 0.000
A30-A49 Other bacterial diseases
0.882 0.118 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.878 0.122 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.877 0.123 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.876 0.124 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.876 0.124 0.000
D00-D09 In situ neoplasms
0.875 0.125 0.000
Z98.1 Arthrodesis status
0.875 0.125 0.000
N30 Cystitis
0.870 0.130 0.000
F43 Reaction to severe stress, and adjustment disorders
0.866 0.134 0.000
Z31 Procreative management
0.866 0.134 0.000
F10.2 Dependence syndrome
0.866 0.134 0.000
O60-O75 Complications of labour and delivery
0.866 0.134 0.000
Z36 Antenatal screening
0.857 0.143 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.854 0.146 0.000
F45 Somatoform disorders
0.853 0.147 0.000
N39 Other disorders of urinary system
0.849 0.151 0.000
Z80 Family history of malignant neoplasm
0.849 0.151 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.845 0.155 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.845 0.155 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.844 0.156 0.000
T39.1 4-Aminophenol derivatives
0.842 0.158 0.000
S50-S59 Injuries to the elbow and forearm
0.841 0.159 0.000
Z91.5 Personal history of self-harm
0.837 0.163 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
N39.3 Stress incontinence
0.835 0.165 0.000
Chapter XI Diseases of the digestive system
0.834 0.166 0.000
E10-E14 Diabetes mellitus
0.833 0.167 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.832 0.168 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.831 0.168 0.000
I51 Complications and ill-defined descriptions of heart disease
0.831 0.169 0.000
I49 Other cardiac arrhythmias
0.827 0.173 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.827 0.173 0.000
Y40.8 Other systemic antibiotics
0.826 0.174 0.000
S10-S19 Injuries to the neck
0.825 0.175 0.000
E40-E46 Malnutrition
0.824 0.176 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.822 0.178 0.000
A00-A09 Intestinal infectious diseases
0.821 0.179 0.000
X60-X84 Intentional self-harm
0.821 0.179 0.000
N00-N08 Glomerular diseases
0.819 0.181 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.818 0.182 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.817 0.183 0.000
D60-D64 Aplastic and other anaemias
0.816 0.183 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.815 0.185 0.000
Z97 Presence of other devices
0.814 0.186 0.000
N76 Other inflammation of vagina and vulva
0.811 0.189 0.000
K70-K77 Diseases of liver
0.810 0.190 0.000
S20-S29 Injuries to the thorax
0.808 0.192 0.000
O20 Haemorrhage in early pregnancy
0.808 0.192 0.000
T40.4 Other synthetic narcotics
0.807 0.193 0.000
I31 Other diseases of pericardium
0.807 0.193 0.000
H53-H54 Visual disturbances and blindness
0.805 0.195 0.000
E66.8 Other obesity
0.801 0.199 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.800 0.200 0.000
T40.2 Other opioids
0.799 0.201 0.000
N20.2 Calculus of kidney with calculus of ureter
0.798 0.202 0.000
I60-I69 Cerebrovascular diseases
0.796 0.204 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.796 0.204 0.000
T79-T79 Certain early complications of trauma
0.796 0.204 0.000
Z34.8 Supervision of other normal pregnancy
0.796 0.204 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
N75 Diseases of Bartholin's gland
0.793 0.207 0.000
I05 Rheumatic mitral valve diseases
0.793 0.207 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
S90-S99 Injuries to the ankle and foot
0.792 0.208 0.000
F60-F69 Disorders of adult personality and behaviour
0.791 0.209 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.790 0.209 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.789 0.211 0.000
D05 Carcinoma in situ of breast
0.788 0.212 0.000
S64 Injury of nerves at wrist and hand level
0.788 0.212 0.000
Y40.0 Penicillins
0.787 0.213 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.786 0.214 0.000
K70 Alcoholic liver disease
0.786 0.214 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.786 0.214 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.786 0.214 0.000
Z57 Occupational exposure to risk-factors
0.784 0.216 0.000
D06 Carcinoma in situ of cervix uteri
0.783 0.217 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.783 0.217 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.783 0.217 0.000
Z63 Other problems related to primary support group, including family circumstances
0.783 0.217 0.000
Z92.3 Personal history of irradiation
0.783 0.217 0.000
F40 Phobic anxiety disorders
0.782 0.218 0.000
Z32 Pregnancy examination and test
0.782 0.218 0.000
W50-W64 Exposure to animate mechanical forces
0.781 0.219 0.000
N30.2 Other chronic cystitis
0.781 0.219 0.000
Z86.0 Personal history of other neoplasms
0.778 0.222 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.778 0.222 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.777 0.223 0.000
S61 Open wound of wrist and hand
0.776 0.224 0.000
T93 Sequelae of injuries of lower limb
0.775 0.225 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.775 0.225 0.000
A41 Other septicaemia
0.775 0.225 0.000
I33 Acute and subacute endocarditis
0.772 0.228 0.000
I30 Acute pericarditis
0.771 0.228 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.771 0.229 0.000
I50.9 Heart failure, unspecified
0.771 0.229 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.771 0.229 0.000
D64 Other anaemias
0.770 0.230 0.000
K86 Other diseases of pancreas
0.769 0.231 0.000
K81 Cholecystitis
0.767 0.233 0.000
N36 Other disorders of urethra
0.767 0.233 0.000
N99-N99 Other disorders of the genitourinary system
0.763 0.237 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.762 0.238 0.000
O24 Diabetes mellitus in pregnancy
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.758 0.242 0.000
Z98.8 Other specified postsurgical states
0.757 0.243 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.757 0.243 0.000
B65-B83 Helminthiases
0.757 0.243 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.757 0.243 0.000
F43.0 Acute stress reaction
0.756 0.243 0.000
D09 Carcinoma in situ of other and unspecified sites
0.756 0.244 0.000
O72 Postpartum haemorrhage
0.755 0.245 0.000
Y52 Agents primarily affecting the cardiovascular system
0.754 0.246 0.000
T43.2 Other and unspecified antidepressants
0.754 0.246 0.000
I38 Endocarditis, valve unspecified
0.752 0.248 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.751 0.249 0.000
S40-S49 Injuries to the shoulder and upper arm
0.750 0.250 0.000
O47 False labour
0.748 0.252 0.000
F20 Schizophrenia
0.748 0.252 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.748 0.252 0.000
V40-V49 Car occupant injured in transport accident
0.747 0.253 0.000
F29 Unspecified nonorganic psychosis
0.747 0.253 0.000
D05.1 Intraductal carcinoma in situ
0.746 0.254 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.745 0.255 0.000
F45.8 Other somatoform disorders
0.743 0.256 0.000
N72 Inflammatory disease of cervix uteri
0.741 0.259 0.000
C50-C50 Malignant neoplasm of breast
0.740 0.260 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.740 0.260 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.738 0.262 0.000
V80-V89 Other land transport accidents
0.737 0.263 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.736 0.264 0.000
K82 Other diseases of gallbladder
0.735 0.265 0.000
E50-E64 Other nutritional deficiencies
0.734 0.266 0.000
V10-V19 Pedal cyclist injured in transport accident
0.733 0.267 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.732 0.268 0.000
K65-K67 Diseases of peritoneum
0.732 0.268 0.000
Y42.7 Androgens and anabolic congeners
0.731 0.269 0.000
T90 Sequelae of injuries of head
0.731 0.269 0.000
S50 Superficial injury of forearm
0.730 0.270 0.000
Z36.8 Other antenatal screening
0.730 0.270 0.000
E46 Unspecified protein-energy malnutrition
0.730 0.270 0.000
S69 Other and unspecified injuries of wrist and hand
0.728 0.272 0.000
E10 Insulin-dependent diabetes mellitus
0.728 0.272 0.000
S60 Superficial injury of wrist and hand
0.727 0.273 0.000
D68 Other coagulation defects
0.727 0.273 0.000
N30.9 Cystitis, unspecified
0.726 0.274 0.000
O16 Unspecified maternal hypertension
0.726 0.274 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.725 0.275 0.000
I36 Nonrheumatic tricuspid valve disorders
0.724 0.276 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.723 0.276 0.000
I34 Nonrheumatic mitral valve disorders
0.723 0.277 0.000
T51 Toxic effect of alcohol
0.723 0.277 0.000
A49 Bacterial infection of unspecified site
0.722 0.278 0.000
I51.9 Heart disease, unspecified
0.722 0.278 0.000
Y85 Sequelae of transport accidents
0.721 0.279 0.000
H55-H59 Other disorders of eye and adnexa
0.720 0.280 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.720 0.280 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.720 0.280 0.000
B35-B49 Mycoses
0.720 0.280 0.000
C83.3 Large cell (diffuse)
0.720 0.280 0.000
D06.9 Cervix, unspecified
0.718 0.282 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
K81.1 Chronic cholecystitis
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
I07 Rheumatic tricuspid valve diseases
0.716 0.284 0.000
F10.9 Unspecified mental and behavioural disorder
0.715 0.284 0.000
F10.8 Other mental and behavioural disorders
0.715 0.284 0.000
F10.7 Residual and late-onset psychotic disorder
0.715 0.284 0.000
F10.6 Amnesic syndrome
0.715 0.284 0.000
F10.5 Psychotic disorder
0.715 0.284 0.000
F10.4 Withdrawal state with delirium
0.715 0.284 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
Z38 Liveborn infants according to place of birth
0.714 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
Y00-Y09 Assault
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X50-X57 Overexertion, travel and privation
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.714 0.286 0.000
F25 Schizoaffective disorders
0.714 0.286 0.000
D64.9 Anaemia, unspecified
0.712 0.288 0.000
S80-S89 Injuries to the knee and lower leg
0.712 0.288 0.000
T31 Burns classified according to extent of body surface involved
0.711 0.289 0.000
T23 Burn and corrosion of wrist and hand
0.711 0.289 0.000
N20.9 Urinary calculus, unspecified
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.290 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.710 0.290 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.710 0.290 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.290 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.710 0.290 0.000
O85-O92 Complications predominantly related to the puerperium
0.710 0.290 0.000
O80-O84 Delivery
0.709 0.291 0.000
Z84 Family history of other conditions
0.707 0.292 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.706 0.294 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.706 0.294 0.000
Y57 Other and unspecified drugs and medicaments
0.706 0.294 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
I49.3 Ventricular premature depolarisation
0.704 0.296 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.704 0.296 0.000
H53 Visual disturbances
0.703 0.296 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.703 0.297 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.703 0.297 0.000
C64-C68 Malignant neoplasms of urinary tract
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.297 0.000
Y58 Bacterial vaccines
0.702 0.297 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.702 0.297 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.297 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.702 0.297 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.297 0.000
Y48 Anaesthetics and therapeutic gases
0.702 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.297 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.297 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.702 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.702 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
B50-B64 Protozoal diseases
0.702 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
Y40.9 Systemic antibiotic, unspecified
0.702 0.298 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.700 0.299 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.700 0.300 0.000
N21 Calculus of lower urinary tract
0.700 0.300 0.000
S62 Fracture at wrist and hand level
0.699 0.300 0.000
Z94 Transplanted organ and tissue status
0.699 0.301 0.000
F45.3 Somatoform autonomic dysfunction
0.699 0.301 0.000
F43.2 Adjustment disorders
0.698 0.302 0.000
T39.0 Salicylates
0.697 0.303 0.000
Z89 Acquired absence of limb
0.696 0.304 0.000
Z91.6 Personal history of other physical trauma
0.695 0.305 0.000
N34 Urethritis and urethral syndrome
0.695 0.305 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.695 0.305 0.000
Z65 Problems related to other psychosocial circumstances
0.694 0.305 0.000
Z64 Problems related to certain psychosocial circumstances
0.694 0.305 0.000
Z62 Other problems related to upbringing
0.694 0.305 0.000
Z61 Problems related to negative life events in childhood
0.694 0.305 0.000
Z59 Problems related to housing and economic circumstances
0.694 0.305 0.000
Z58 Problems related to physical environment
0.694 0.305 0.000
Z56 Problems related to employment and unemployment
0.694 0.305 0.000
Z55 Problems related to education and literacy
0.694 0.305 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
Z31.4 Procreative investigation and testing
0.693 0.307 0.000
N25-N29 Other disorders of kidney and ureter
0.693 0.307 0.000
N30.3 Trigonitis
0.692 0.307 0.000
I69 Sequelae of cerebrovascular disease
0.692 0.308 0.000
I28 Other diseases of pulmonary vessels
0.692 0.308 0.000
O23 Infections of genito-urinary tract in pregnancy
0.691 0.309 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
O66 Other obstructed labour
0.691 0.309 0.000
K82.4 Cholesterolosis of gallbladder
0.691 0.309 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.690 0.310 0.000
S67 Crushing injury of wrist and hand
0.690 0.310 0.000
S65 Injury of blood vessels at wrist and hand level
0.690 0.310 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.690 0.310 0.000
Z74 Problems related to care-provider dependency
0.689 0.310 0.000
K86.1 Other chronic pancreatitis
0.688 0.312 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.688 0.312 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.687 0.313 0.000
F42 Obsessive-compulsive disorder
0.687 0.313 0.000
O20.8 Other haemorrhage in early pregnancy
0.687 0.313 0.000
I05.9 Mitral valve disease, unspecified
0.686 0.314 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.686 0.314 0.000
I44 Atrioventricular and left bundle-branch block
0.685 0.315 0.000
K70.9 Alcoholic liver disease, unspecified
0.684 0.316 0.000
Z31.2 In vitro fertilisation
0.684 0.316 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.683 0.317 0.000
K81.9 Cholecystitis, unspecified
0.683 0.317 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.682 0.318 0.000
K85 Acute pancreatitis
0.682 0.318 0.000
S51 Open wound of forearm
0.682 0.318 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
H43-H45 Disorders of vitreous body and globe
0.681 0.318 0.000
K76 Other diseases of liver
0.681 0.319 0.000
F48 Other neurotic disorders
0.681 0.319 0.000
F44 Dissociative [conversion] disorders
0.681 0.319 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.681 0.319 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.680 0.320 0.000
B25-B34 Other viral diseases
0.679 0.320 0.000
H20 Iridocyclitis
0.679 0.321 0.000
A80-A89 Viral infections of the central nervous system
0.679 0.321 0.000
H25-H28 Disorders of lens
0.678 0.322 0.000
Z36.9 Antenatal screening, unspecified
0.678 0.322 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.678 0.322 0.000
N37 Urethral disorders in diseases classified elsewhere
0.678 0.322 0.000
N33 Bladder disorders in diseases classified elsewhere
0.678 0.322 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.678 0.322 0.000
S70-S79 Injuries to the hip and thigh
0.676 0.324 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.674 0.326 0.000
F17.1 Harmful use
0.674 0.326 0.000
E10.3 With ophthalmic complications
0.674 0.326 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.673 0.326 0.000
Z91.7 Personal history of female genital mutilation
0.673 0.326 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.673 0.326 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.673 0.326 0.000
Z91.2 Personal history of poor personal hygiene
0.673 0.326 0.000
F43.1 Posttraumatic stress disorder
0.672 0.328 0.000
O20.0 Threatened abortion
0.672 0.328 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.672 0.328 0.000
Z34.0 Supervision of normal first pregnancy
0.672 0.328 0.000
D09.0 Bladder
0.672 0.328 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.671 0.329 0.000
O72.1 Other immediate postpartum haemorrhage
0.670 0.330 0.000
Y54.5 Other diuretics
0.669 0.331 0.000
K65 Peritonitis
0.669 0.331 0.000
O29 Complications of anaesthesia during pregnancy
0.668 0.331 0.000
O28 Abnormal findings on antenatal screening of mother
0.668 0.331 0.000
O22 Venous complications in pregnancy
0.668 0.331 0.000
O21 Excessive vomiting in pregnancy
0.668 0.331 0.000
O25 Malnutrition in pregnancy
0.668 0.331 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.668 0.332 0.000
W00-W19 Falls
0.668 0.332 0.000
E67 Other hyperalimentation
0.668 0.332 0.000
E68 Sequelae of hyperalimentation
0.668 0.332 0.000
E65 Localised adiposity
0.668 0.332 0.000
O40 Polyhydramnios
0.668 0.332 0.000
I51.4 Myocarditis, unspecified
0.668 0.332 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.667 0.333 0.000
A04 Other bacterial intestinal infections
0.667 0.333 0.000
I49.9 Cardiac arrhythmia, unspecified
0.666 0.334 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.666 0.334 0.000
K70.1 Alcoholic hepatitis
0.665 0.335 0.000
Z92.8 Personal history of other medical treatment
0.665 0.335 0.000
O71 Other obstetric trauma
0.665 0.335 0.000
N76.8 Other specified inflammation of vagina and vulva
0.663 0.337 0.000
N17-N19 Renal failure
0.663 0.337 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.662 0.338 0.000
S64.4 Injury of digital nerve of other finger
0.662 0.338 0.000
F40.2 Specific (isolated) phobias
0.662 0.338 0.000
N76.0 Acute vaginitis
0.662 0.338 0.000
Y40.7 Antifungal antibiotics, systemically used
0.661 0.339 0.000
Y40.6 Rifamycins
0.661 0.339 0.000
Y40.5 Aminoglycosides
0.661 0.339 0.000
Y40.4 Tetracyclines
0.661 0.339 0.000
Y40.3 Macrolides
0.661 0.339 0.000
Y40.2 Chloramphenicol group
0.661 0.339 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.661 0.339 0.000
O30 Multiple gestation
0.660 0.340 0.000
I31.9 Disease of pericardium, unspecified
0.660 0.340 0.000
Z60.9 Problem related to social environment, unspecified
0.659 0.340 0.000
Z60.8 Other problems related to social environment
0.659 0.340 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.659 0.340 0.000
Z60.4 Social exclusion and rejection
0.659 0.340 0.000
Z60.3 Acculturation difficulty
0.659 0.340 0.000
Z60.1 Atypical parenting situation
0.659 0.340 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.659 0.340 0.000
Z35.5 Supervision of elderly primigravida
0.659 0.341 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.659 0.341 0.000
T40.8 Lysergide [LSD]
0.659 0.341 0.000
T40.7 Cannabis (derivatives)
0.659 0.341 0.000
T40.6 Other and unspecified narcotics
0.659 0.341 0.000
T40.5 Cocaine
0.659 0.341 0.000
T40.3 Methadone
0.659 0.341 0.000
T40.1 Heroin
0.659 0.341 0.000
T40.0 Opium
0.659 0.341 0.000
S12 Fracture of neck
0.658 0.342 0.000
K75 Other inflammatory liver diseases
0.657 0.343 0.000
O42 Premature rupture of membranes
0.657 0.343 0.000
H54 Blindness and low vision
0.657 0.343 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.656 0.344 0.000
E66.1 Drug-induced obesity
0.656 0.344 0.000
E66.0 Obesity due to excess calories
0.656 0.344 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.656 0.344 0.000
O63 Long labour
0.656 0.344 0.000
E11 Non-insulin-dependent diabetes mellitus
0.656 0.344 0.000
K70.3 Alcoholic cirrhosis of liver
0.655 0.345 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.655 0.345 0.000
N73.5 Female pelvic peritonitis, unspecified
0.655 0.345 0.000
N73.4 Female chronic pelvic peritonitis
0.655 0.345 0.000
N73.3 Female acute pelvic peritonitis
0.655 0.345 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.655 0.345 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.655 0.345 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.655 0.345 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.654 0.345 0.000
N03 Chronic nephritic syndrome
0.654 0.346 0.000
Chapter XXII Codes for special purposes
0.654 0.346 0.000
I05.1 Rheumatic mitral insufficiency
0.653 0.347 0.000
K70.4 Alcoholic hepatic failure
0.653 0.347 0.000
A08 Viral and other specified intestinal infections
0.652 0.348 0.000
I62 Other nontraumatic intracranial haemorrhage
0.652 0.348 0.000
T93.1 Sequelae of fracture of femur
0.651 0.349 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.651 0.349 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.650 0.350 0.000
Z92.9 Personal history of medical treatment, unspecified
0.650 0.350 0.000
Z92.5 Personal history of rehabilitation measures
0.650 0.350 0.000
Z92.0 Personal history of contraception
0.650 0.350 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.650 0.350 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.649 0.351 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.649 0.351 0.000
S61.8 Open wound of other parts of wrist and hand
0.648 0.352 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.648 0.352 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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