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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72748988
log Bayes Factor = 19.0653
Chromosome 9   position 92,041,530  (GRCh37) Explore rs72748988 on Ensembl!
Variant rs72748988 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Z51 Other medical care
0.998 0.002 0.000
Z51.2 Other chemotherapy
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.995 0.005 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.994 0.006 0.000
M45-M49 Spondylopathies
0.994 0.006 0.000
M50-M54 Other dorsopathies
0.992 0.008 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.990 0.010 0.000
T81 Complications of procedures, not elsewhere classified
0.989 0.011 0.000
T39.1 4-Aminophenol derivatives
0.987 0.013 0.000
M54 Dorsalgia
0.987 0.013 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
M47 Spondylosis
0.977 0.023 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.976 0.024 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
D12.3 Transverse colon
0.972 0.028 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.971 0.029 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.962 0.038 0.000
M54.5 Low back pain
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.952 0.048 0.000
E00-E07 Disorders of thyroid gland
0.950 0.050 0.000
G90-G99 Other disorders of the nervous system
0.949 0.051 0.000
D00-D09 In situ neoplasms
0.948 0.052 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.947 0.053 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.942 0.058 0.000
E20-E35 Disorders of other endocrine glands
0.942 0.058 0.000
M54.56 Low back pain (Lumbar region)
0.935 0.065 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.933 0.067 0.000
D12.6 Colon, unspecified
0.931 0.069 0.000
A41 Other septicaemia
0.930 0.070 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.927 0.073 0.000
D12.5 Sigmoid colon
0.927 0.073 0.000
S50-S59 Injuries to the elbow and forearm
0.926 0.074 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.921 0.079 0.000
M47.8 Other spondylosis
0.920 0.080 0.000
D12.0 Caecum
0.919 0.081 0.000
T39.0 Salicylates
0.918 0.082 0.000
E04 Other non-toxic goitre
0.916 0.084 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.915 0.085 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.911 0.089 0.000
F60-F69 Disorders of adult personality and behaviour
0.910 0.090 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.908 0.092 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.908 0.092 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.907 0.093 0.000
Z41 Procedures for purposes other than remedying health state
0.905 0.095 0.000
Chapter VII Diseases of the eye and adnexa
0.902 0.098 0.000
F20 Schizophrenia
0.899 0.101 0.000
M48 Other spondylopathies
0.896 0.104 0.000
F43 Reaction to severe stress, and adjustment disorders
0.896 0.104 0.000
F30-F39 Mood [affective] disorders
0.893 0.107 0.000
T43.2 Other and unspecified antidepressants
0.892 0.108 0.000
H40-H42 Glaucoma
0.886 0.114 0.000
D32 Benign neoplasm of meninges
0.885 0.115 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.885 0.115 0.000
G51 Facial nerve disorders
0.879 0.121 0.000
Z48 Other surgical follow-up care
0.878 0.122 0.000
D27 Benign neoplasm of ovary
0.877 0.123 0.000
M54.1 Radiculopathy
0.876 0.124 0.000
H40 Glaucoma
0.875 0.125 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.874 0.126 0.000
E27 Other disorders of adrenal gland
0.870 0.130 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.869 0.131 0.000
Z96 Presence of other functional implants
0.867 0.133 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.866 0.134 0.000
D22 Melanocytic naevi
0.865 0.135 0.000
S80-S89 Injuries to the knee and lower leg
0.864 0.136 0.000
B25-B34 Other viral diseases
0.863 0.137 0.000
Z51.3 Blood transfusion without reported diagnosis
0.861 0.139 0.000
T81.9 Unspecified complication of procedure
0.860 0.140 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.859 0.141 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.854 0.146 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.852 0.148 0.000
M70-M79 Other soft tissue disorders
0.851 0.149 0.000
G91 Hydrocephalus
0.851 0.149 0.000
M47.2 Other spondylosis with radiculopathy
0.850 0.150 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.850 0.150 0.000
M54.4 Lumbago with sciatica
0.849 0.151 0.000
Z43 Attention to artificial openings
0.848 0.152 0.000
A41.9 Septicaemia, unspecified
0.848 0.152 0.000
F60 Specific personality disorders
0.847 0.153 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.847 0.153 0.000
D05 Carcinoma in situ of breast
0.847 0.153 0.000
Z91.5 Personal history of self-harm
0.845 0.155 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.843 0.157 0.000
D06 Carcinoma in situ of cervix uteri
0.843 0.157 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.842 0.158 0.000
S10-S19 Injuries to the neck
0.841 0.159 0.000
F20.9 Schizophrenia, unspecified
0.840 0.160 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.838 0.162 0.000
G30-G32 Other degenerative diseases of the nervous system
0.838 0.162 0.000
E04.2 Non-toxic multinodular goitre
0.838 0.162 0.000
H40.1 Primary open-angle glaucoma
0.837 0.163 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.837 0.163 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.834 0.165 0.000
S70-S79 Injuries to the hip and thigh
0.833 0.167 0.000
M47.9 Spondylosis, unspecified
0.832 0.168 0.000
T87 Complications peculiar to reattachment and amputation
0.829 0.171 0.000
Z87 Personal history of other diseases and conditions
0.829 0.171 0.000
H40.9 Glaucoma, unspecified
0.828 0.172 0.000
S52 Fracture of forearm
0.827 0.173 0.000
F29 Unspecified nonorganic psychosis
0.826 0.174 0.000
G54 Nerve root and plexus disorders
0.826 0.174 0.000
E04.1 Non-toxic single thyroid nodule
0.825 0.175 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.825 0.175 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.825 0.175 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.824 0.176 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.824 0.176 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.824 0.176 0.000
Z96.6 Presence of orthopaedic joint implants
0.824 0.176 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.823 0.177 0.000
M50 Cervical disk disorders
0.823 0.177 0.000
M40-M43 Deforming dorsopathies
0.821 0.179 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.817 0.183 0.000
Chapter XX External causes of morbidity and mortality
0.816 0.184 0.000
C64-C68 Malignant neoplasms of urinary tract
0.815 0.185 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.815 0.185 0.000
M47.82 Other spondylosis (Cervical region)
0.813 0.187 0.000
Z93 Artificial opening status
0.812 0.188 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
D11 Benign neoplasm of major salivary glands
0.809 0.191 0.000
Z94 Transplanted organ and tissue status
0.809 0.191 0.000
M48.0 Spinal stenosis
0.806 0.194 0.000
G95 Other diseases of spinal cord
0.806 0.194 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.805 0.195 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.804 0.196 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.803 0.197 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.802 0.198 0.000
C43 Malignant melanoma of skin
0.800 0.200 0.000
A00-A09 Intestinal infectious diseases
0.798 0.202 0.000
F43.0 Acute stress reaction
0.796 0.204 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.794 0.206 0.000
Z57 Occupational exposure to risk-factors
0.793 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.793 0.207 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.792 0.208 0.000
G40-G47 Episodic and paroxysmal disorders
0.790 0.210 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.788 0.212 0.000
Z51.8 Other specified medical care
0.785 0.215 0.000
M45 Ankylosing spondylitis
0.785 0.215 0.000
Z49 Care involving dialysis
0.784 0.216 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.783 0.217 0.000
D12.9 Anus and anal canal
0.782 0.218 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.782 0.218 0.000
E22 Hyperfunction of pituitary gland
0.781 0.219 0.000
S50 Superficial injury of forearm
0.780 0.219 0.000
Z63 Other problems related to primary support group, including family circumstances
0.780 0.220 0.000
G51.0 Bell's palsy
0.780 0.220 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.779 0.221 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.779 0.221 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.775 0.225 0.000
E23 Hypofunction and other disorders of pituitary gland
0.775 0.225 0.000
M47.86 Other spondylosis (Lumbar region)
0.774 0.226 0.000
M54.55 Low back pain (Thoracolumbar region)
0.774 0.226 0.000
G91.1 Obstructive hydrocephalus
0.774 0.226 0.000
Z52 Donors of organs and tissues
0.774 0.226 0.000
E05.9 Thyrotoxicosis, unspecified
0.774 0.226 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.774 0.226 0.000
F43.2 Adjustment disorders
0.773 0.227 0.000
T86 Failure and rejection of transplanted organs and tissues
0.773 0.227 0.000
T42.4 Benzodiazepines
0.773 0.227 0.000
M54.16 Radiculopathy (Lumbar region)
0.772 0.228 0.000
D03 Melanoma in situ
0.772 0.228 0.000
Z48.8 Other specified surgical follow-up care
0.771 0.229 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.771 0.229 0.000
D32.9 Meninges, unspecified
0.771 0.229 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.771 0.229 0.000
G58 Other mononeuropathies
0.770 0.230 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.769 0.231 0.000
D06.9 Cervix, unspecified
0.768 0.232 0.000
D31 Benign neoplasm of eye and adnexa
0.767 0.233 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.766 0.234 0.000
Z89 Acquired absence of limb
0.765 0.235 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.764 0.236 0.000
B34 Viral infection of unspecified site
0.762 0.237 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.762 0.238 0.000
F99-F99 Unspecified mental disorder
0.760 0.240 0.000
G93 Other disorders of brain
0.760 0.240 0.000
M77 Other enthesopathies
0.759 0.241 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.758 0.242 0.000
C15-C26 Malignant neoplasms of digestive organs
0.756 0.244 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.755 0.245 0.000
F43.1 Posttraumatic stress disorder
0.755 0.245 0.000
Z96.8 Presence of other specified functional implants
0.753 0.247 0.000
F60.9 Personality disorder, unspecified
0.753 0.247 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.753 0.247 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.753 0.247 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.752 0.248 0.000
E34 Other endocrine disorders
0.751 0.249 0.000
D12.7 Rectosigmoid junction
0.750 0.250 0.000
E65-E68 Obesity and other hyperalimentation
0.750 0.250 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.749 0.251 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.747 0.252 0.000
B99-B99 Other infectious diseases
0.746 0.254 0.000
Z60 Problems related to social environment
0.745 0.254 0.000
M46 Other inflammatory spondylopathies
0.745 0.255 0.000
B65-B83 Helminthiases
0.744 0.256 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.744 0.256 0.000
M54.9 Dorsalgia, unspecified
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.742 0.258 0.000
A41.8 Other specified septicaemia
0.742 0.258 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.742 0.258 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.741 0.259 0.000
Z98 Other postsurgical states
0.740 0.260 0.000
M54.2 Cervicalgia
0.738 0.262 0.000
M54.57 Low back pain (Lumbosacral region)
0.736 0.264 0.000
G35 Multiple sclerosis
0.735 0.265 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.735 0.265 0.000
D05.1 Intraductal carcinoma in situ
0.735 0.265 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.734 0.266 0.000
Chapter VIII Diseases of the ear and mastoid process
0.734 0.266 0.000
F32 Depressive episode
0.733 0.267 0.000
F60.3 Emotionally unstable personality disorder
0.732 0.268 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.732 0.268 0.000
M54.6 Pain in thoracic spine
0.731 0.269 0.000
F80-F89 Disorders of psychological development
0.731 0.269 0.000
H55-H59 Other disorders of eye and adnexa
0.731 0.269 0.000
F33 Recurrent depressive disorder
0.729 0.271 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.729 0.271 0.000
D34 Benign neoplasm of thyroid gland
0.727 0.273 0.000
S90-S99 Injuries to the ankle and foot
0.727 0.273 0.000
M54.3 Sciatica
0.723 0.276 0.000
S72 Fracture of femur
0.722 0.278 0.000
M47.1 Other spondylosis with myelopathy
0.721 0.279 0.000
Z94.8 Other transplanted organ and tissue status
0.721 0.279 0.000
C09 Malignant neoplasm of tonsil
0.721 0.279 0.000
M53 Other dorsopathies, not elsewhere classified
0.721 0.279 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.720 0.279 0.000
H40.5 Glaucoma secondary to other eye disorders
0.720 0.280 0.000
Z54 Convalescence
0.719 0.280 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.719 0.281 0.000
H40.8 Other glaucoma
0.719 0.281 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.719 0.281 0.000
E24 Cushing's syndrome
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.717 0.283 0.000
G53.0 Postzoster neuralgia
0.717 0.283 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.716 0.284 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.716 0.284 0.000
T39.4 Antirheumatics, not elsewhere classified
0.716 0.284 0.000
T39.2 Pyrazolone derivatives
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
G52 Disorders of other cranial nerves
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
Z51.9 Medical care, unspecified
0.716 0.284 0.000
Z51.6 Desensitisation to allergens
0.716 0.284 0.000
B35-B49 Mycoses
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.284 0.000
F70-F79 Mental retardation
0.715 0.284 0.000
F23 Acute and transient psychotic disorders
0.715 0.285 0.000
D30 Benign neoplasm of urinary organs
0.715 0.285 0.000
D32.0 Cerebral meninges
0.714 0.286 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.714 0.286 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.713 0.287 0.000
D29 Benign neoplasm of male genital organs
0.713 0.287 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.713 0.287 0.000
D19 Benign neoplasm of mesothelial tissue
0.713 0.287 0.000
D16 Benign neoplasm of bone and articular cartilage
0.713 0.287 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.713 0.287 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.713 0.287 0.000
D12.1 Appendix
0.713 0.287 0.000
M49 Spondylopathies in diseases classified elsewhere
0.713 0.287 0.000
F31 Bipolar affective disorder
0.712 0.288 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
G95.9 Disease of spinal cord, unspecified
0.709 0.291 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.709 0.291 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.709 0.291 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.709 0.291 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.709 0.291 0.000
A40 Streptococcal septicaemia
0.709 0.291 0.000
M41 Scoliosis
0.708 0.292 0.000
M54.8 Other dorsalgia
0.707 0.292 0.000
M54.0 Panniculitis affecting regions of neck and back
0.707 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.707 0.293 0.000
M48.02 Spinal stenosis (Cervical region)
0.706 0.294 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.706 0.294 0.000
G40 Epilepsy
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.705 0.295 0.000
F22 Persistent delusional disorders
0.705 0.295 0.000
F25 Schizoaffective disorders
0.704 0.296 0.000
A08 Viral and other specified intestinal infections
0.703 0.297 0.000
F20.0 Paranoid schizophrenia
0.702 0.297 0.000
S81 Open wound of lower leg
0.702 0.297 0.000
Z46 Fitting and adjustment of other devices
0.702 0.298 0.000
H53-H54 Visual disturbances and blindness
0.701 0.299 0.000
M86-M90 Other osteopathies
0.701 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.299 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.700 0.300 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.700 0.300 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.700 0.300 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.698 0.302 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.697 0.302 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.697 0.302 0.000
M75 Shoulder lesions
0.697 0.303 0.000
S52.1 Fracture of upper end of radius
0.697 0.303 0.000
T43.9 Psychotropic drug, unspecified
0.696 0.304 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
T43.6 Psychostimulants with abuse potential
0.696 0.304 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.696 0.304 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.696 0.304 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.305 0.000
T85.2 Mechanical complication of intraocular lens
0.694 0.306 0.000
Z48.0 Attention to surgical dressings and sutures
0.693 0.307 0.000
G90 Disorders of autonomic nervous system
0.693 0.307 0.000
T51 Toxic effect of alcohol
0.692 0.308 0.000
E27.9 Disorder of adrenal gland, unspecified
0.691 0.309 0.000
M65-M68 Disorders of synovium and tendon
0.691 0.309 0.000
B34.9 Viral infection, unspecified
0.691 0.309 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.690 0.310 0.000
F28 Other nonorganic psychotic disorders
0.690 0.310 0.000
F24 Induced delusional disorder
0.690 0.310 0.000
F21 Schizotypal disorder
0.690 0.310 0.000
M54.12 Radiculopathy (Cervical region)
0.689 0.311 0.000
D26 Other benign neoplasms of uterus
0.687 0.313 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.686 0.314 0.000
F41 Other anxiety disorders
0.686 0.314 0.000
Z63.0 Problems in relationship with spouse or partner
0.684 0.316 0.000
M54.54 Low back pain-Thoracic
0.684 0.316 0.000
M54.53 Low back pain-Cervicothoracic
0.684 0.316 0.000
M54.52 Low back pain-Cervical
0.684 0.316 0.000
M54.51 Low back pain-Occipit-atl-axl
0.684 0.316 0.000
Z57.2 Occupational exposure to dust
0.684 0.316 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.683 0.317 0.000
A48 Other bacterial diseases, not elsewhere classified
0.683 0.317 0.000
A44 Bartonellosis
0.683 0.317 0.000
A43 Nocardiosis
0.683 0.317 0.000
A42 Actinomycosis
0.683 0.317 0.000
A39 Meningococcal infection
0.683 0.317 0.000
A37 Whooping cough
0.683 0.317 0.000
A36 Diphtheria
0.683 0.317 0.000
A32 Listeriosis
0.683 0.317 0.000
A31 Infection due to other mycobacteria
0.683 0.317 0.000
A30 Leprosy [Hansen's disease]
0.683 0.317 0.000
A38 Scarlet fever
0.683 0.317 0.000
A35 Other tetanus
0.683 0.317 0.000
A34 Obstetrical tetanus
0.683 0.317 0.000
A33 Tetanus neonatorum
0.683 0.317 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.683 0.317 0.000
C91 Lymphoid leukaemia
0.683 0.317 0.000
Z96.2 Presence of otological and audiological implants
0.683 0.317 0.000
Z45 Adjustment and management of implanted device
0.683 0.317 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.683 0.317 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.682 0.317 0.000
M77.9 Enthesopathy, unspecified
0.682 0.318 0.000
Z42 Follow-up care involving plastic surgery
0.682 0.318 0.000
Z93.3 Colostomy status
0.682 0.318 0.000
Z43.5 Attention to cyctostomy
0.682 0.318 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.682 0.318 0.000
E04.9 Non-toxic goitre, unspecified
0.681 0.318 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.681 0.319 0.000
E00 Congenital iodine-deficiency syndrome
0.681 0.319 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.681 0.319 0.000
Z93.6 Other artificial openings of urinary tract status
0.680 0.320 0.000
G96 Other disorders of central nervous system
0.680 0.320 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.680 0.320 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.680 0.320 0.000
G92 Toxic encephalopathy
0.680 0.320 0.000
M50.1 Cervical disk disorder with radiculopathy
0.680 0.320 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.679 0.320 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.679 0.320 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.679 0.320 0.000
A80-A89 Viral infections of the central nervous system
0.678 0.322 0.000
H10-H13 Disorders of conjunctiva
0.678 0.322 0.000
E27.8 Other specified disorders of adrenal gland
0.678 0.322 0.000
M50.3 Other cervical disk degeneration
0.677 0.323 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.677 0.323 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.324 0.000
S50.9 Superficial injury of forearm, unspecified
0.676 0.324 0.000
D11.0 Parotid gland
0.676 0.324 0.000
M47.89 Other spondylosis (Site unspecified)
0.675 0.325 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.675 0.325 0.000
E32 Diseases of thymus
0.675 0.325 0.000
E31 Polyglandular dysfunction
0.675 0.325 0.000
E30 Disorders of puberty, not elsewhere classified
0.675 0.325 0.000
E29 Testicular dysfunction
0.675 0.325 0.000
E26 Hyperaldosteronism
0.675 0.325 0.000
E25 Adrenogenital disorders
0.675 0.325 0.000
E20 Hypoparathyroidism
0.675 0.325 0.000
B91 Sequelae of poliomyelitis
0.674 0.325 0.000
S51 Open wound of forearm
0.674 0.325 0.000
E07 Other disorders of thyroid
0.674 0.326 0.000
Z96.0 Presence of urogenital implants
0.674 0.326 0.000
C34 Malignant neoplasm of bronchus and lung
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.673 0.327 0.000
D05.0 Lobular carcinoma in situ
0.673 0.327 0.000
F42 Obsessive-compulsive disorder
0.673 0.327 0.000
Z93.0 Tracheostomy status
0.672 0.328 0.000
G20-G26 Extrapyramidal and movement disorders
0.672 0.328 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.671 0.329 0.000
E40-E46 Malnutrition
0.669 0.330 0.000
F48 Other neurotic disorders
0.669 0.331 0.000
F44 Dissociative [conversion] disorders
0.669 0.331 0.000
G70-G73 Diseases of myoneural junction and muscle
0.669 0.331 0.000
A46 Erysipelas
0.668 0.331 0.000
T87.4 Infection of amputation stump
0.668 0.332 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.668 0.332 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.668 0.332 0.000
C15 Malignant neoplasm of oesophagus
0.667 0.333 0.000
Z97 Presence of other devices
0.667 0.333 0.000
A41.4 Septicaemia due to anaerobes
0.667 0.333 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.667 0.333 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.667 0.333 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.667 0.333 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.666 0.334 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.666 0.334 0.000
S82 Fracture of lower leg, including ankle
0.665 0.335 0.000
M20-M25 Other joint disorders
0.665 0.335 0.000
M80-M85 Disorders of bone density and structure
0.665 0.335 0.000
W00-W19 Falls
0.665 0.335 0.000
Z65 Problems related to other psychosocial circumstances
0.665 0.335 0.000
Z64 Problems related to certain psychosocial circumstances
0.665 0.335 0.000
Z62 Other problems related to upbringing
0.665 0.335 0.000
Z61 Problems related to negative life events in childhood
0.665 0.335 0.000
Z59 Problems related to housing and economic circumstances
0.665 0.335 0.000
Z58 Problems related to physical environment
0.665 0.335 0.000
Z56 Problems related to employment and unemployment
0.665 0.335 0.000
Z55 Problems related to education and literacy
0.665 0.335 0.000
F50 Eating disorders
0.664 0.336 0.000
S59 Other and unspecified injuries of forearm
0.664 0.336 0.000
S58 Traumatic amputation of forearm
0.664 0.336 0.000
S57 Crushing injury of forearm
0.664 0.336 0.000
S56 Injury of muscle and tendon at forearm level
0.664 0.336 0.000
S55 Injury of blood vessels at forearm level
0.664 0.336 0.000
S54 Injury of nerves at forearm level
0.664 0.336 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.664 0.336 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.663 0.337 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.663 0.337 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.662 0.338 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.662 0.338 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.662 0.338 0.000
G51.9 Disorder of facial nerve, unspecified
0.661 0.339 0.000
M54.50 Low back pain (Multiple sites in spine)
0.659 0.340 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.659 0.340 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.659 0.340 0.000
M47.84 Other spondylosis (Thoracic region)
0.659 0.340 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.659 0.340 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.659 0.340 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.658 0.342 0.000
D12.4 Descending colon
0.658 0.342 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.658 0.342 0.000
E04.8 Other specified non-toxic goitre
0.656 0.343 0.000
E04.0 Non-toxic diffuse goitre
0.656 0.343 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.656 0.344 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.656 0.344 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.656 0.344 0.000
T42.3 Barbiturates
0.656 0.344 0.000
T42.2 Succinimides and oxazolidinediones
0.656 0.344 0.000
T42.1 Iminostilbenes
0.656 0.344 0.000
T42.0 Hydantoin derivatives
0.656 0.344 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.655 0.345 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.655 0.345 0.000
D03.5 Melanoma in situ of trunk
0.655 0.345 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.654 0.346 0.000
G56 Mononeuropathies of upper limb
0.653 0.347 0.000
F68 Other disorders of adult personality and behaviour
0.652 0.347 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.652 0.347 0.000
F65 Disorders of sexual preference
0.652 0.347 0.000
F64 Gender identity disorders
0.652 0.347 0.000
F63 Habit and impulse disorders
0.652 0.347 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.652 0.347 0.000
F69 Unspecified disorder of adult personality and behaviour
0.652 0.347 0.000
F61 Mixed and other personality disorders
0.652 0.347 0.000
T87.6 Other and unspecified complications of amputation stump
0.651 0.348 0.000
T50.8 Diagnostic agents
0.651 0.349 0.000
T50.7 Analeptics and opioid receptor antagonists
0.651 0.349 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.651 0.349 0.000
T50.5 Appetite depressants
0.651 0.349 0.000
T50.4 Drugs affecting uric acid metabolism
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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