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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72770140
log Bayes Factor = 7.00192
Chromosome 2   position 4,666,772  (GRCh37) Explore rs72770140 on Ensembl!
Variant rs72770140 is part of Cluster X0076

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
C15-C26 Malignant neoplasms of digestive organs
0.993 0.007 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.992 0.008 0.000
E20-E35 Disorders of other endocrine glands
0.991 0.009 0.000
G40-G47 Episodic and paroxysmal disorders
0.991 0.009 0.000
C78.7 Secondary malignant neoplasm of liver
0.990 0.010 0.000
O26.8 Other specified pregnancy-related conditions
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.980 0.020 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.976 0.024 0.000
G47 Sleep disorders
0.974 0.026 0.000
C18 Malignant neoplasm of colon
0.970 0.030 0.000
C78.0 Secondary malignant neoplasm of lung
0.954 0.046 0.000
E70-E90 Metabolic disorders
0.950 0.050 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.950 0.050 0.000
N17-N19 Renal failure
0.947 0.053 0.000
N17 Acute renal failure
0.941 0.059 0.000
N18 Chronic renal failure
0.939 0.061 0.000
Chapter V Mental and behavioural disorders
0.937 0.063 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
N17.9 Acute renal failure, unspecified
0.935 0.065 0.000
G47.3 Sleep apnoea
0.933 0.067 0.000
Chapter XIV Diseases of the genitourinary system
0.930 0.070 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.929 0.071 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.926 0.074 0.000
C18.0 Caecum
0.925 0.075 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.921 0.079 0.000
Q60-Q64 Congenital malformations of the urinary system
0.920 0.080 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.916 0.084 0.000
F41 Other anxiety disorders
0.916 0.084 0.000
G40 Epilepsy
0.915 0.085 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.914 0.086 0.000
F41.9 Anxiety disorder, unspecified
0.913 0.087 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.911 0.089 0.000
C25 Malignant neoplasm of pancreas
0.908 0.092 0.000
C78.2 Secondary malignant neoplasm of pleura
0.905 0.095 0.000
N18.5 Chronic kidney disease, stage 5
0.902 0.098 0.000
E23 Hypofunction and other disorders of pituitary gland
0.899 0.101 0.000
Z75 Problems related to medical facilities and other health care
0.895 0.105 0.000
D00-D09 In situ neoplasms
0.894 0.106 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.893 0.107 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.892 0.108 0.000
O20 Haemorrhage in early pregnancy
0.891 0.109 0.000
E86 Volume depletion
0.890 0.110 0.000
O16 Unspecified maternal hypertension
0.888 0.112 0.000
Z45 Adjustment and management of implanted device
0.887 0.113 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.879 0.121 0.000
Z45.2 Adjustment and management of vascular access device
0.879 0.121 0.000
A30-A49 Other bacterial diseases
0.877 0.123 0.000
E65-E68 Obesity and other hyperalimentation
0.875 0.124 0.000
E87.5 Hyperkalaemia
0.874 0.126 0.000
G40.9 Epilepsy, unspecified
0.872 0.128 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.871 0.129 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.871 0.129 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.866 0.134 0.000
N18.0 End-stage renal disease
0.864 0.136 0.000
Z73 Problems related to life-management difficulty
0.859 0.141 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.857 0.143 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.854 0.146 0.000
Q61 Cystic kidney disease
0.852 0.148 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.852 0.148 0.000
O26.9 Pregnancy-related condition, unspecified
0.847 0.153 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.846 0.154 0.000
B35-B49 Mycoses
0.842 0.158 0.000
Chapter VII Diseases of the eye and adnexa
0.841 0.159 0.000
E21.0 Primary hyperparathyroidism
0.840 0.160 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.838 0.162 0.000
E27 Other disorders of adrenal gland
0.838 0.162 0.000
C18.5 Splenic flexure
0.837 0.163 0.000
C25.9 Pancreas, unspecified
0.832 0.168 0.000
D05 Carcinoma in situ of breast
0.831 0.169 0.000
A41 Other septicaemia
0.830 0.170 0.000
C18.6 Descending colon
0.829 0.171 0.000
D03 Melanoma in situ
0.827 0.173 0.000
O24 Diabetes mellitus in pregnancy
0.827 0.173 0.000
Z60 Problems related to social environment
0.826 0.174 0.000
O21 Excessive vomiting in pregnancy
0.823 0.177 0.000
Z49 Care involving dialysis
0.822 0.178 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.820 0.180 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.820 0.180 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.818 0.182 0.000
G70-G73 Diseases of myoneural junction and muscle
0.816 0.184 0.000
Q50-Q56 Congenital malformations of genital organs
0.812 0.188 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.812 0.188 0.000
E23.0 Hypopituitarism
0.812 0.188 0.000
F30-F39 Mood [affective] disorders
0.809 0.191 0.000
D05.1 Intraductal carcinoma in situ
0.806 0.194 0.000
A41.9 Septicaemia, unspecified
0.806 0.194 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.805 0.195 0.000
E24 Cushing's syndrome
0.804 0.196 0.000
N18.2 Chronic kidney disease, stage 2
0.802 0.198 0.000
Z51 Other medical care
0.802 0.198 0.000
O00-O08 Pregnancy with abortive outcome
0.797 0.203 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.797 0.203 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.795 0.205 0.000
G47.8 Other sleep disorders
0.794 0.206 0.000
E66 Obesity
0.793 0.207 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.793 0.207 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.793 0.207 0.000
G47.9 Sleep disorder, unspecified
0.791 0.209 0.000
F45 Somatoform disorders
0.789 0.211 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.788 0.212 0.000
C34 Malignant neoplasm of bronchus and lung
0.788 0.212 0.000
C21 Malignant neoplasm of anus and anal canal
0.788 0.212 0.000
E22 Hyperfunction of pituitary gland
0.788 0.212 0.000
H30-H36 Disorders of choroid and retina
0.786 0.214 0.000
E89.3 Postprocedural hypopituitarism
0.786 0.214 0.000
C80 Malignant neoplasm without specification of site
0.786 0.214 0.000
Z58 Problems related to physical environment
0.785 0.215 0.000
Z30 Contraceptive management
0.783 0.217 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.782 0.218 0.000
N19 Unspecified renal failure
0.781 0.219 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.779 0.221 0.000
Z42 Follow-up care involving plastic surgery
0.778 0.222 0.000
F80-F89 Disorders of psychological development
0.777 0.223 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.777 0.223 0.000
C18.7 Sigmoid colon
0.776 0.224 0.000
O20.0 Threatened abortion
0.776 0.224 0.000
E34 Other endocrine disorders
0.774 0.226 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.771 0.229 0.000
Q63 Other congenital malformations of kidney
0.770 0.230 0.000
E66.8 Other obesity
0.769 0.231 0.000
G50 Disorders of trigeminal nerve
0.765 0.235 0.000
Z51.1 Chemotherapy session for neoplasm
0.764 0.236 0.000
C77.1 Intrathoracic lymph nodes
0.763 0.237 0.000
E73 Lactose intolerance
0.761 0.239 0.000
G45.4 Transient global amnesia
0.760 0.240 0.000
N17.0 Acute renal failure with tubular necrosis
0.759 0.241 0.000
Z30.2 Sterilisation
0.757 0.243 0.000
B25-B34 Other viral diseases
0.756 0.244 0.000
F41.1 Generalised anxiety disorder
0.754 0.246 0.000
B37 Candidiasis
0.753 0.247 0.000
Z56 Problems related to employment and unemployment
0.751 0.248 0.000
C34.3 Lower lobe, bronchus or lung
0.751 0.249 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.751 0.249 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.749 0.251 0.000
N18.9 Chronic renal failure, unspecified
0.749 0.251 0.000
Z76 Persons encountering health services in other circumstances
0.748 0.252 0.000
O36 Maternal care for other known or suspected foetal problems
0.748 0.252 0.000
O23 Infections of genito-urinary tract in pregnancy
0.744 0.256 0.000
E29 Testicular dysfunction
0.742 0.258 0.000
A46 Erysipelas
0.741 0.259 0.000
Q66 Congenital deformities of feet
0.738 0.262 0.000
E26 Hyperaldosteronism
0.737 0.262 0.000
E16 Other disorders of pancreatic internal secretion
0.737 0.263 0.000
A80-A89 Viral infections of the central nervous system
0.737 0.263 0.000
C18.3 Hepatic flexure
0.737 0.263 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.735 0.265 0.000
O80-O84 Delivery
0.735 0.265 0.000
N72 Inflammatory disease of cervix uteri
0.732 0.268 0.000
Q61.3 Polycystic kidney, unspecified
0.731 0.269 0.000
H43-H45 Disorders of vitreous body and globe
0.731 0.269 0.000
Z32 Pregnancy examination and test
0.731 0.269 0.000
O85-O92 Complications predominantly related to the puerperium
0.729 0.271 0.000
G44 Other headache syndromes
0.729 0.271 0.000
Q80-Q89 Other congenital malformations
0.728 0.272 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.728 0.272 0.000
Z73.8 Other problems related to life-management difficulty
0.726 0.274 0.000
G50.0 Trigeminal neuralgia
0.725 0.275 0.000
Z74 Problems related to care-provider dependency
0.725 0.275 0.000
E10-E14 Diabetes mellitus
0.725 0.275 0.000
Q61.2 Polycystic kidney, adult type
0.724 0.276 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.724 0.276 0.000
Z60.2 Living alone
0.724 0.276 0.000
C79 Secondary malignant neoplasm of other sites
0.723 0.277 0.000
E85 Amyloidosis
0.722 0.278 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.722 0.278 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.721 0.279 0.000
E87.2 Acidosis
0.719 0.281 0.000
Z51.5 Palliative care
0.719 0.281 0.000
C51-C58 Malignant neoplasms of female genital organs
0.719 0.281 0.000
E28 Ovarian dysfunction
0.717 0.283 0.000
E89.0 Postprocedural hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
O29 Complications of anaesthesia during pregnancy
0.716 0.284 0.000
O28 Abnormal findings on antenatal screening of mother
0.716 0.284 0.000
O22 Venous complications in pregnancy
0.716 0.284 0.000
O25 Malnutrition in pregnancy
0.716 0.284 0.000
Z75.8 Other problems related to medical facilities and other health care
0.716 0.284 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.715 0.285 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.714 0.286 0.000
C17 Malignant neoplasm of small intestine
0.713 0.287 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.711 0.289 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.711 0.289 0.000
O26.5 Maternal hypotension syndrome
0.711 0.289 0.000
O26.4 Herpes gestationis
0.711 0.289 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.711 0.289 0.000
O26.2 Pregnancy care of habitual aborter
0.711 0.289 0.000
O26.1 Low weight gain in pregnancy
0.711 0.289 0.000
O26.0 Excessive weight gain in pregnancy
0.711 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.711 0.289 0.000
E32 Diseases of thymus
0.711 0.289 0.000
E31 Polyglandular dysfunction
0.711 0.289 0.000
E30 Disorders of puberty, not elsewhere classified
0.711 0.289 0.000
E25 Adrenogenital disorders
0.711 0.289 0.000
E20 Hypoparathyroidism
0.711 0.289 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.711 0.289 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.711 0.289 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.710 0.290 0.000
C18.9 Colon, unspecified
0.709 0.291 0.000
E23.2 Diabetes insipidus
0.707 0.293 0.000
C23 Malignant neoplasm of gallbladder
0.707 0.293 0.000
Z59 Problems related to housing and economic circumstances
0.707 0.293 0.000
N25-N29 Other disorders of kidney and ureter
0.706 0.294 0.000
C77.5 Intrapelvic lymph nodes
0.705 0.295 0.000
F42 Obsessive-compulsive disorder
0.705 0.295 0.000
E27.8 Other specified disorders of adrenal gland
0.704 0.296 0.000
Z75.4 Unavailability and inaccessibility of other helping agencies
0.703 0.297 0.000
C22.9 Liver, unspecified
0.702 0.298 0.000
O20.8 Other haemorrhage in early pregnancy
0.702 0.298 0.000
Z49.0 Preparatory care for dialysis
0.701 0.299 0.000
C25.0 Head of pancreas
0.700 0.300 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.699 0.300 0.000
Q35-Q37 Cleft lip and cleft palate
0.699 0.300 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.699 0.300 0.000
Q00-Q07 Congenital malformations of the nervous system
0.698 0.302 0.000
G47.4 Narcolepsy and cataplexy
0.698 0.302 0.000
G47.2 Disorders of the sleep-wake schedule
0.698 0.302 0.000
N18.8 Other chronic renal failure
0.698 0.302 0.000
F33 Recurrent depressive disorder
0.698 0.302 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.697 0.303 0.000
O21.0 Mild hyperemesis gravidarum
0.697 0.303 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
C18.8 Overlapping lesion of colon
0.695 0.304 0.000
Z49.2 Other dialysis
0.694 0.306 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.694 0.306 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.694 0.306 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.694 0.306 0.000
Z38 Liveborn infants according to place of birth
0.692 0.307 0.000
F31 Bipolar affective disorder
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.692 0.308 0.000
Z58.1 Exposure to air pollution
0.692 0.308 0.000
F45.8 Other somatoform disorders
0.691 0.309 0.000
D69 Purpura and other haemorrhagic conditions
0.689 0.311 0.000
H36 Retinal disorders in diseases classified elsewhere
0.688 0.312 0.000
O48 Prolonged pregnancy
0.688 0.312 0.000
N18.4 Chronic kidney disease, stage 4
0.687 0.313 0.000
G41 Status epilepticus
0.686 0.314 0.000
H10-H13 Disorders of conjunctiva
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.684 0.316 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.683 0.317 0.000
Z41 Procedures for purposes other than remedying health state
0.681 0.319 0.000
E84 Cystic fibrosis
0.681 0.319 0.000
E79 Disorders of purine and pyrimidine metabolism
0.681 0.319 0.000
E77 Disorders of glycoprotein metabolism
0.681 0.319 0.000
E76 Disorders of glycosaminoglycan metabolism
0.681 0.319 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.681 0.319 0.000
E74 Other disorders of carbohydrate metabolism
0.681 0.319 0.000
E72 Other disorders of amino-acid metabolism
0.681 0.319 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.681 0.319 0.000
E70 Disorders of aromatic amino-acid metabolism
0.681 0.319 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.681 0.319 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.681 0.319 0.000
O45 Premature separation of placenta [abruptio placentae]
0.680 0.320 0.000
F30 Manic episode
0.680 0.320 0.000
G90-G99 Other disorders of the nervous system
0.678 0.322 0.000
Z60.8 Other problems related to social environment
0.678 0.322 0.000
Z31 Procreative management
0.677 0.323 0.000
N17.8 Other acute renal failure
0.675 0.325 0.000
N17.2 Acute renal failure with medullary necrosis
0.675 0.325 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.675 0.325 0.000
H43 Disorders of vitreous body
0.674 0.326 0.000
N18.1 Chronic kidney disease, stage 1
0.673 0.326 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.672 0.328 0.000
F70-F79 Mental retardation
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
B50-B64 Protozoal diseases
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.671 0.329 0.000
H34 Retinal vascular occlusions
0.671 0.329 0.000
E24.9 Cushing's syndrome, unspecified
0.670 0.330 0.000
G45.3 Amaurosis fugax
0.669 0.331 0.000
E40-E46 Malnutrition
0.668 0.332 0.000
Q63.0 Accessory kidney
0.668 0.332 0.000
Q61.0 Congenital single renal cyst
0.668 0.332 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.668 0.332 0.000
C34.0 Main bronchus
0.667 0.333 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.667 0.333 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.667 0.333 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.667 0.333 0.000
Z34 Supervision of normal pregnancy
0.667 0.333 0.000
G72 Other myopathies
0.667 0.333 0.000
O15 Eclampsia
0.666 0.334 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.666 0.334 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.666 0.334 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
O04 Medical abortion
0.665 0.335 0.000
F48 Other neurotic disorders
0.664 0.336 0.000
F44 Dissociative [conversion] disorders
0.664 0.336 0.000
C18.1 Appendix
0.660 0.340 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.660 0.340 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.660 0.340 0.000
G45.0 Vertebro-basilar artery syndrome
0.660 0.340 0.000
B49 Unspecified mycosis
0.660 0.340 0.000
Q64 Other congenital malformations of urinary system
0.660 0.340 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.660 0.340 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.660 0.340 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.660 0.340 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.659 0.340 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.658 0.341 0.000
D55-D59 Haemolytic anaemias
0.657 0.343 0.000
Z65 Problems related to other psychosocial circumstances
0.657 0.343 0.000
Z64 Problems related to certain psychosocial circumstances
0.657 0.343 0.000
Z62 Other problems related to upbringing
0.657 0.343 0.000
Z61 Problems related to negative life events in childhood
0.657 0.343 0.000
Z55 Problems related to education and literacy
0.657 0.343 0.000
F41.8 Other specified anxiety disorders
0.656 0.343 0.000
F41.3 Other mixed anxiety disorders
0.656 0.343 0.000
C77.2 Intra-abdominal lymph nodes
0.656 0.344 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.656 0.344 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.656 0.344 0.000
G40.5 Special epileptic syndromes
0.656 0.344 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.656 0.344 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.656 0.344 0.000
Z71.9 Counselling, unspecified
0.656 0.344 0.000
C25.2 Tail of pancreas
0.655 0.344 0.000
Q66.8 Other congenital deformities of feet
0.654 0.346 0.000
O02 Other abnormal products of conception
0.653 0.347 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.653 0.347 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.653 0.347 0.000
H16 Keratitis
0.653 0.347 0.000
H15 Disorders of sclera
0.652 0.348 0.000
Z75.2 Other waiting period for investigation and treatment
0.652 0.348 0.000
C25.8 Overlapping lesion of pancreas
0.651 0.349 0.000
C25.7 Other parts of pancreas
0.651 0.349 0.000
C25.4 Endocrine pancreas
0.651 0.349 0.000
C25.3 Pancreatic duct
0.651 0.349 0.000
C25.1 Body of pancreas
0.651 0.349 0.000
D05.0 Lobular carcinoma in situ
0.651 0.349 0.000
C15 Malignant neoplasm of oesophagus
0.649 0.351 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.649 0.351 0.000
C64-C68 Malignant neoplasms of urinary tract
0.647 0.353 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.645 0.354 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.645 0.355 0.000
Q76 Congenital malformations of spine and bony thorax
0.645 0.355 0.000
E23.7 Disorder of pituitary gland, unspecified
0.645 0.355 0.000
E23.6 Other disorders of pituitary gland
0.645 0.355 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.645 0.355 0.000
E23.1 Drug-induced hypopituitarism
0.645 0.355 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.644 0.356 0.000
O41 Other disorders of amniotic fluid and membranes
0.644 0.356 0.000
Z49.1 Extracorporeal dialysis
0.643 0.357 0.000
F80 Specific developmental disorders of speech and language
0.642 0.357 0.000
Z75.9 Unspecified problem related to medical facilities and other health care
0.642 0.358 0.000
Z75.5 Holiday relief care
0.642 0.358 0.000
Z75.0 Medical services not available in home
0.642 0.358 0.000
A48 Other bacterial diseases, not elsewhere classified
0.642 0.358 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.641 0.358 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.641 0.359 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.641 0.359 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.641 0.359 0.000
N75 Diseases of Bartholin's gland
0.640 0.359 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.640 0.360 0.000
E21.4 Other specified disorders of parathyroid gland
0.640 0.360 0.000
E21.2 Other hyperparathyroidism
0.640 0.360 0.000
O36.5 Maternal care for poor foetal growth
0.640 0.360 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.640 0.360 0.000
D03.5 Melanoma in situ of trunk
0.640 0.360 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.639 0.361 0.000
H18 Other disorders of cornea
0.637 0.363 0.000
E16.2 Hypoglycaemia, unspecified
0.637 0.363 0.000
Z51.8 Other specified medical care
0.636 0.364 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.636 0.364 0.000
Z45.3 Adjustment and management of implanted hearing device
0.636 0.364 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.635 0.365 0.000
H17 Corneal scars and opacities
0.633 0.367 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.633 0.367 0.000
G56 Mononeuropathies of upper limb
0.633 0.367 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.633 0.367 0.000
E27.1 Primary adrenocortical insufficiency
0.631 0.369 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.631 0.369 0.000
E27.9 Disorder of adrenal gland, unspecified
0.631 0.369 0.000
G70 Myasthenia gravis and other myoneural disorders
0.631 0.369 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.631 0.369 0.000
E87.4 Mixed disorder of acid-base balance
0.630 0.369 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.631 0.369 0.000
B37.0 Candidal stomatitis
0.631 0.369 0.000
A44 Bartonellosis
0.629 0.371 0.000
A43 Nocardiosis
0.629 0.371 0.000
A42 Actinomycosis
0.629 0.371 0.000
A39 Meningococcal infection
0.629 0.371 0.000
A37 Whooping cough
0.629 0.371 0.000
A36 Diphtheria
0.629 0.371 0.000
A32 Listeriosis
0.629 0.371 0.000
A31 Infection due to other mycobacteria
0.629 0.371 0.000
A30 Leprosy [Hansen's disease]
0.629 0.371 0.000
A38 Scarlet fever
0.629 0.371 0.000
A35 Other tetanus
0.629 0.371 0.000
A34 Obstetrical tetanus
0.629 0.371 0.000
A33 Tetanus neonatorum
0.629 0.371 0.000
A40 Streptococcal septicaemia
0.629 0.371 0.000
E67 Other hyperalimentation
0.628 0.372 0.000
E68 Sequelae of hyperalimentation
0.628 0.372 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.627 0.373 0.000
E73.9 Lactose intolerance, unspecified
0.626 0.374 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.624 0.376 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.624 0.376 0.000
C31 Malignant neoplasm of accessory sinuses
0.624 0.376 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.624 0.376 0.000
C37 Malignant neoplasm of thymus
0.624 0.376 0.000
C33 Malignant neoplasm of trachea
0.624 0.376 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.624 0.376 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.624 0.376 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.624 0.376 0.000
E89.5 Postprocedural testicular hypofunction
0.624 0.376 0.000
E89.4 Postprocedural ovarian failure
0.624 0.376 0.000
E89.1 Postprocedural hypoinsulinaemia
0.624 0.376 0.000
C24.0 Extrahepatic bile duct
0.624 0.376 0.000
D69.6 Thrombocytopenia, unspecified
0.624 0.376 0.000
C77.8 Lymph nodes of multiple regions
0.622 0.378 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.622 0.378 0.000
B37.3 Candidiasis of vulva and vagina
0.622 0.378 0.000
Z52 Donors of organs and tissues
0.622 0.378 0.000
G80 Infantile cerebral palsy
0.620 0.380 0.000
E34.8 Other specified endocrine disorders
0.618 0.382 0.000
H36.0 Diabetic retinopathy
0.618 0.382 0.000
B35 Dermatophytosis
0.618 0.382 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.617 0.383 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.617 0.383 0.000
G57 Mononeuropathies of lower limb
0.616 0.384 0.000
Z73.6 Limitation of activities due to disability
0.616 0.384 0.000
Z73.5 Social role conflict, not elsewhere classified
0.616 0.384 0.000
Z73.4 Inadequate social skills, not elsewhere classified
0.616 0.384 0.000
Z73.2 Lack of relaxation and leisure
0.616 0.384 0.000
Z73.1 Accentuation of personality traits
0.616 0.384 0.000
Z73.0 Burn-out
0.616 0.384 0.000
Z54 Convalescence
0.616 0.384 0.000
G81 Hemiplegia
0.616 0.384 0.000
B37.4 Candidiasis of other urogenital sites
0.615 0.385 0.000
Z32.1 Pregnancy confirmed
0.614 0.385 0.000
O33 Maternal care for known or suspected disproportion
0.614 0.385 0.000
O31 Complications specific to multiple gestation
0.614 0.385 0.000
O40 Polyhydramnios
0.614 0.385 0.000
H35 Other retinal disorders
0.614 0.386 0.000
H20 Iridocyclitis
0.613 0.387 0.000
Q78 Other osteochondrodysplasias
0.612 0.387 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.612 0.387 0.000
Q75 Other congenital malformations of skull and face bones
0.612 0.387 0.000
Q74 Other congenital malformations of limb(s)
0.612 0.387 0.000
Q73 Reduction defects of unspecified limb
0.612 0.387 0.000
Q72 Reduction defects of lower limb
0.612 0.387 0.000
Q71 Reduction defects of upper limb
0.612 0.387 0.000
Q70 Syndactyly
0.612 0.387 0.000
Q69 Polydactyly
0.612 0.387 0.000
Q68 Other congenital musculoskeletal deformities
0.612 0.387 0.000
Q65 Congenital deformities of hip
0.612 0.387 0.000
C22.1 Intrahepatic bile duct carcinoma
0.611 0.389 0.000
Q61.9 Cystic kidney disease, unspecified
0.611 0.389 0.000
Q61.8 Other cystic kidney diseases
0.611 0.389 0.000
Q61.5 Medullary cystic kidney
0.611 0.389 0.000
Q61.4 Renal dysplasia
0.611 0.389 0.000
Q61.1 Polycystic kidney, infantile type
0.611 0.389 0.000
E65 Localised adiposity
0.611 0.389 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.610 0.389 0.000
Z71.6 Tobacco abuse counselling
0.609 0.391 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.609 0.391 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.609 0.391 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.609 0.391 0.000
F84 Pervasive developmental disorders
0.609 0.391 0.000
Z45.1 Adjustment and management of infusion pump
0.609 0.391 0.000
G40.8 Other epilepsy
0.608 0.392 0.000
B34 Viral infection of unspecified site
0.607 0.393 0.000
E15 Nondiabetic hypoglycaemic coma
0.607 0.393 0.000
E89.2 Postprocedural hypoparathyroidism
0.607 0.393 0.000
F99-F99 Unspecified mental disorder
0.606 0.394 0.000
B65-B83 Helminthiases
0.605 0.395 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.605 0.395 0.000
C18.4 Transverse colon
0.605 0.395 0.000
D06 Carcinoma in situ of cervix uteri
0.605 0.395 0.000
B48 Other mycoses, not elsewhere classified
0.604 0.396 0.000
B47 Mycetoma
0.604 0.396 0.000
B46 Zygomycosis
0.604 0.396 0.000
B45 Cryptococcosis
0.604 0.396 0.000
B43 Chromomycosis and phaeomycotic abscess
0.604 0.396 0.000
B42 Sporotrichosis
0.604 0.396 0.000
B41 Paracoccidioidomycosis
0.604 0.396 0.000
B40 Blastomycosis
0.604 0.396 0.000
B39 Histoplasmosis
0.604 0.396 0.000
B38 Coccidioidomycosis
0.604 0.396 0.000
B36 Other superficial mycoses
0.604 0.396 0.000
E50-E64 Other nutritional deficiencies
0.601 0.399 0.000
E27.5 Adrenomedullary hyperfunction
0.601 0.399 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.601 0.399 0.000
E27.2 Addisonian crisis
0.601 0.399 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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