TreeWAS – Variant ID: rs72907046

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIV Diseases of the genitourinary system	1.000	0.000
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
I20-I25 Ischaemic heart diseases	0.999	0.001
N80-N98 Noninflammatory disorders of female genital tract	0.999	0.001
D50-D53 Nutritional anaemias	0.998	0.002
Chapter XI Diseases of the digestive system	0.997	0.003
D50 Iron deficiency anaemia	0.995	0.005
I20 Angina pectoris	0.995	0.005
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
N20-N23 Urolithiasis	0.994	0.006
N85 Other noninflammatory disorders of uterus, except cervix	0.993	0.007
N20 Calculus of kidney and ureter	0.990	0.010
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.990	0.010
I30-I52 Other forms of heart disease	0.989	0.011
D50.9 Iron deficiency anaemia, unspecified	0.988	0.012
D60-D64 Aplastic and other anaemias	0.985	0.015
N30-N39 Other diseases of urinary system	0.982	0.018
N85.8 Other specified noninflammatory disorders of uterus	0.980	0.020
R10 Abdominal and pelvic pain	0.979	0.021
R10.1 Pain localised to upper abdomen	0.973	0.027
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.973	0.027
I20.9 Angina pectoris, unspecified	0.969	0.031
D64 Other anaemias	0.968	0.032
Chapter IV Endocrine, nutritional and metabolic diseases	0.967	0.033
N20.0 Calculus of kidney	0.967	0.033
M70-M79 Other soft tissue disorders	0.966	0.034
K90-K93 Other diseases of the digestive system	0.963	0.037
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.963	0.037
I20.0 Unstable angina	0.963	0.037
D64.9 Anaemia, unspecified	0.956	0.044
N20.1 Calculus of ureter	0.951	0.049
Chapter VIII Diseases of the ear and mastoid process	0.949	0.051
Chapter I Certain infectious and parasitic diseases	0.948	0.052
N83.2 Other and unspecified ovarian cysts	0.948	0.052
N39 Other disorders of urinary system	0.947	0.053
I35 Nonrheumatic aortic valve disorders	0.940	0.060
M79 Other soft tissue disorders, not elsewhere classified	0.934	0.066
N39.3 Stress incontinence	0.926	0.074
Chapter XII Diseases of the skin and subcutaneous tissue	0.925	0.075
E00-E07 Disorders of thyroid gland	0.921	0.079
K70-K77 Diseases of liver	0.918	0.082
N87 Dysplasia of cervix uteri	0.918	0.082
K92 Other diseases of digestive system	0.916	0.084
I70-I79 Diseases of arteries, arterioles and capillaries	0.912	0.088
Chapter XXI Factors influencing health status and contact with health services	0.909	0.091
R18 Ascites	0.905	0.095
M79.6 Pain in limb	0.902	0.098
I44 Atrioventricular and left bundle-branch block	0.899	0.101
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.897	0.103
I05-I09 Chronic rheumatic heart diseases	0.895	0.105
H90-H95 Other disorders of ear	0.893	0.107
N70-N77 Inflammatory diseases of female pelvic organs	0.892	0.108
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.892	0.108
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.892	0.108
I25 Chronic ischaemic heart disease	0.891	0.109
Z00-Z13 Persons encountering health services for examination and investigation	0.883	0.117
M20-M25 Other joint disorders	0.879	0.121
N60-N64 Disorders of breast	0.879	0.121
K92.2 Gastro-intestinal haemorrhage, unspecified	0.877	0.123
S60-S69 Injuries to the wrist and hand	0.875	0.124
M45-M49 Spondylopathies	0.872	0.128
L00-L08 Infections of the skin and subcutaneous tissue	0.870	0.130
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.864	0.136
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.863	0.137
I35.0 Aortic (valve) stenosis	0.862	0.138
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.858	0.142
E03 Other hypothyroidism	0.855	0.145
B25-B34 Other viral diseases	0.853	0.147
I31 Other diseases of pericardium	0.851	0.149
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.850	0.150
I21 Acute myocardial infarction	0.849	0.151
N17-N19 Renal failure	0.848	0.152
Z12 Special screening examination for neoplasms	0.845	0.155
D51 Vitamin B12 deficiency anaemia	0.844	0.156
M23 Internal derangement of knee	0.842	0.158
N85.9 Noninflammatory disorder of uterus, unspecified	0.840	0.160
I25.1 Atherosclerotic heart disease	0.838	0.162
N85.4 Malposition of uterus	0.836	0.164
D80-D89 Certain disorders involving the immune mechanism	0.835	0.165
I51 Complications and ill-defined descriptions of heart disease	0.833	0.167
D63 Anaemia in chronic diseases classified elsewhere	0.832	0.168
K40-K46 Hernia	0.831	0.169
R10.4 Other and unspecified abdominal pain	0.830	0.170
T36-T50 Poisoning by drugs, medicaments and biological substances	0.828	0.172
M79.67 Pain in limb (Ankle and foot)	0.827	0.173
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.821	0.179
K55-K64 Other diseases of intestines	0.819	0.181
Z12.1 Special screening examination for neoplasm of intestinal tract	0.818	0.182
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.816	0.184
I21.9 Acute myocardial infarction, unspecified	0.816	0.184
K90 Intestinal malabsorption	0.815	0.185
E65-E68 Obesity and other hyperalimentation	0.814	0.186
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.812	0.188
I60-I69 Cerebrovascular diseases	0.809	0.191
S70-S79 Injuries to the hip and thigh	0.808	0.191
N72 Inflammatory disease of cervix uteri	0.808	0.192
E03.9 Hypothyroidism, unspecified	0.808	0.192
L20-L30 Dermatitis and eczema	0.808	0.192
T85 Complications of other internal prosthetic devices, implants and grafts	0.804	0.196
N39.8 Other specified disorders of urinary system	0.804	0.196
E20-E35 Disorders of other endocrine glands	0.804	0.196
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.804	0.196
H65-H75 Diseases of middle ear and mastoid	0.804	0.196
R12 Heartburn	0.803	0.197
T81 Complications of procedures, not elsewhere classified	0.802	0.198
I35.2 Aortic (valve) stenosis with insufficiency	0.798	0.202
R93 Abnormal findings on diagnostic imaging of other body structures	0.798	0.202
R47-R49 Symptoms and signs involving speech and voice	0.797	0.203
M79.60 Pain in limb (Multiple sites)	0.796	0.204
N87.9 Dysplasia of cervix uteri, unspecified	0.796	0.204
K35-K38 Diseases of appendix	0.795	0.205
H93 Other disorders of ear, not elsewhere classified	0.795	0.205
N32 Other disorders of bladder	0.794	0.206
B95-B98 Bacterial, viral and other infectious agents	0.793	0.207
E04 Other non-toxic goitre	0.791	0.209
S40-S49 Injuries to the shoulder and upper arm	0.790	0.210
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.789	0.211
M48 Other spondylopathies	0.789	0.211
M65-M68 Disorders of synovium and tendon	0.789	0.211
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.785	0.215
N21 Calculus of lower urinary tract	0.785	0.215
M50-M54 Other dorsopathies	0.784	0.216
S80-S89 Injuries to the knee and lower leg	0.783	0.217
I34 Nonrheumatic mitral valve disorders	0.783	0.217
D50.8 Other iron deficiency anaemias	0.782	0.218
K75 Other inflammatory liver diseases	0.780	0.220
R11 Nausea and vomiting	0.779	0.221
N85.1 Endometrial adenomatous hyperplasia	0.779	0.221
L08 Other local infections of skin and subcutaneous tissue	0.778	0.221
E50-E64 Other nutritional deficiencies	0.778	0.222
L03 Cellulitis	0.777	0.222
I38 Endocarditis, valve unspecified	0.777	0.223
K44 Diaphragmatic hernia	0.777	0.223
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.774	0.226
R05 Cough	0.768	0.232
M70 Soft tissue disorders related to use, overuse and pressure	0.768	0.232
N97 Female infertility	0.767	0.233
E10-E14 Diabetes mellitus	0.767	0.233
Z95 Presence of cardiac and vascular implants and grafts	0.767	0.233
I74 Arterial embolism and thrombosis	0.765	0.235
M75 Shoulder lesions	0.765	0.235
K70 Alcoholic liver disease	0.764	0.236
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.764	0.236
M80-M85 Disorders of bone density and structure	0.760	0.239
N87.1 Moderate cervical dysplasia	0.760	0.240
T86 Failure and rejection of transplanted organs and tissues	0.760	0.240
N89 Other noninflammatory disorders of vagina	0.758	0.241
K20-K31 Diseases of oesophagus, stomach and duodenum	0.758	0.242
S90-S99 Injuries to the ankle and foot	0.758	0.242
R30-R39 Symptoms and signs involving the urinary system	0.757	0.243
N90 Other noninflammatory disorders of vulva and perineum	0.756	0.243
N10-N16 Renal tubulo-interstitial diseases	0.756	0.244
N31.8 Other neuromuscular dysfunction of bladder	0.755	0.245
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.752	0.248
L03.1 Cellulitis of other parts of limb	0.752	0.248
N92 Excessive, frequent and irregular menstruation	0.751	0.249
B34 Viral infection of unspecified site	0.751	0.249
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.750	0.250
K80 Cholelithiasis	0.750	0.250
M40-M43 Deforming dorsopathies	0.749	0.251
N95 Menopausal and other perimenopausal disorders	0.749	0.251
I77 Other disorders of arteries and arterioles	0.747	0.252
I95-I99 Other and unspecified disorders of the circulatory system	0.747	0.253
I44.7 Left bundle-branch block, unspecified	0.747	0.253
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.746	0.253
R14 Flatulence and related conditions	0.746	0.254
I31.3 Pericardial effusion (noninflammatory)	0.745	0.255
N85.0 Endometrial glandular hyperplasia	0.743	0.257
I44.2 Atrioventricular block, complete	0.740	0.260
I08 Multiple valve diseases	0.740	0.260
M79.8 Other specified soft tissue disorders	0.740	0.260
M23.8 Other internal derangements of knee	0.739	0.261
N20.2 Calculus of kidney with calculus of ureter	0.738	0.262
Q20-Q28 Congenital malformations of the circulatory system	0.738	0.262
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.738	0.262
N60 Benign mammary dysplasia	0.736	0.263
K59 Other functional intestinal disorders	0.736	0.264
M86-M90 Other osteopathies	0.735	0.265
T66-T78 Other and unspecified effects of external causes	0.735	0.265
K25 Gastric ulcer	0.734	0.266
I20.8 Other forms of angina pectoris	0.734	0.266
N36 Other disorders of urethra	0.732	0.268
I33 Acute and subacute endocarditis	0.731	0.269
Z98 Other postsurgical states	0.730	0.270
R04 Haemorrhage from respiratory passages	0.730	0.270
M48.0 Spinal stenosis	0.730	0.270
M77 Other enthesopathies	0.729	0.270
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.729	0.271
N83.0 Follicular cyst of ovary	0.728	0.272
S66 Injury of muscle and tendon at wrist and hand level	0.728	0.272
K83 Other diseases of biliary tract	0.727	0.273
Z95.8 Presence of other cardiac and vascular implants and grafts	0.727	0.273
I44.0 Atrioventricular block, first degree	0.726	0.274
Z09.0 Follow-up examination after surgery for other conditions	0.726	0.274
K56 Paralytic ileus and intestinal obstruction without hernia	0.725	0.275
H93.1 Tinnitus	0.724	0.276
M35 Other systemic involvement of connective tissue	0.724	0.276
R91 Abnormal findings on diagnostic imaging of lung	0.724	0.276
I07 Rheumatic tricuspid valve diseases	0.723	0.276
D63.0 Anaemia in neoplastic disease	0.723	0.277
Z08 Follow-up examination after treatment for malignant neoplasm	0.722	0.278
M23.3 Other meniscus derangements	0.722	0.278
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.722	0.278
E06 Thyroiditis	0.722	0.278
R41 Other symptoms and signs involving cognitive functions and awareness	0.722	0.278
B15-B19 Viral hepatitis	0.722	0.278
Chapter XXII Codes for special purposes	0.721	0.279
T88 Other complications of surgical and medical care, not elsewhere classified	0.720	0.279
I78 Diseases of capillaries	0.720	0.280
N63 Unspecified lump in breast	0.719	0.281
I35.1 Aortic (valve) insufficiency	0.719	0.281
K76 Other diseases of liver	0.719	0.281
Chapter II Neoplasms	0.718	0.282
A00-A09 Intestinal infectious diseases	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
D55-D59 Haemolytic anaemias	0.717	0.283
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.717	0.283
M79.65 Pain in limb (Pelvic region and thigh)	0.717	0.283
H91 Other hearing loss	0.716	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
M79.0 Rheumatism, unspecified	0.716	0.284
I23 Certain current complications following acute myocardial infarction	0.716	0.284
N98 Complications associated with artificial fertilisation	0.716	0.284
N91 Absent, scanty and rare menstruation	0.716	0.284
N82 Fistulae involving female genital tract	0.716	0.284
N96 Habitual aborter	0.716	0.284
N30 Cystitis	0.716	0.284
D53 Other nutritional anaemias	0.715	0.284
D52 Folate deficiency anaemia	0.715	0.284
D86 Sarcoidosis	0.715	0.285
N87.0 Mild cervical dysplasia	0.714	0.286
D50.1 Sideropenic dysphagia	0.713	0.286
I20.1 Angina pectoris with documented spasm	0.713	0.287
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.713	0.287
M91-M94 Chondropathies	0.713	0.287
M60-M63 Disorders of muscles	0.713	0.287
M00-M03 Infectious arthropathies	0.713	0.287
N22 Calculus of urinary tract in diseases classified elsewhere	0.713	0.287
T79-T79 Certain early complications of trauma	0.713	0.287
T33-T35 Frostbite	0.713	0.287
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T15-T19 Effects of foreign body entering through natural orifice	0.713	0.287
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
N85.7 Haematometra	0.712	0.288
N85.6 Intra-uterine synechiae	0.712	0.288
N85.5 Inversion of uterus	0.712	0.288
N85.3 Subinvolution of uterus	0.712	0.288
I05 Rheumatic mitral valve diseases	0.711	0.289
S20-S29 Injuries to the thorax	0.711	0.289
N25-N29 Other disorders of kidney and ureter	0.710	0.290
N20.9 Urinary calculus, unspecified	0.710	0.290
R23 Other skin changes	0.710	0.290
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.709	0.291
I52 Other heart disorders in diseases classified elsewhere	0.709	0.291
I48 Atrial fibrillation and flutter	0.709	0.291
I43 Cardiomyopathy in diseases classified elsewhere	0.709	0.291
I41 Myocarditis in diseases classified elsewhere	0.709	0.291
I40 Acute myocarditis	0.709	0.291
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.709	0.291
I37 Pulmonary valve disorders	0.709	0.291
I36 Nonrheumatic tricuspid valve disorders	0.709	0.291
I32 Pericarditis in diseases classified elsewhere	0.709	0.291
I30 Acute pericarditis	0.709	0.291
I50 Heart failure	0.708	0.292
I25.2 Old myocardial infarction	0.708	0.292
S62 Fracture at wrist and hand level	0.707	0.293
D70-D77 Other diseases of blood and blood-forming organs	0.706	0.293
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.706	0.294
D62 Acute posthaemorrhagic anaemia	0.706	0.294
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.705	0.295
L30 Other dermatitis	0.705	0.295
N00-N08 Glomerular diseases	0.704	0.295
H90 Conductive and sensorineural hearing loss	0.704	0.296
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.704	0.296
N37 Urethral disorders in diseases classified elsewhere	0.704	0.296
N34 Urethritis and urethral syndrome	0.704	0.296
N33 Bladder disorders in diseases classified elsewhere	0.704	0.296
M23.2 Derangement of meniscus due to old tear or injury	0.704	0.296
E66 Obesity	0.704	0.296
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.704	0.296
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.704	0.296
N61 Inflammatory disorders of breast	0.702	0.298
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.701	0.299
B35-B49 Mycoses	0.701	0.299
H92 Otalgia and effusion of ear	0.700	0.300
R21 Rash and other nonspecific skin eruption	0.699	0.301
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.699	0.301
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.699	0.301
A50-A64 Infections with a predominantly sexual mode of transmission	0.698	0.302
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.697	0.302
N83.7 Haematoma of broad ligament	0.697	0.302
N83.6 Haematosalpinx	0.697	0.302
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.697	0.302
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.697	0.302
N83.3 Acquired atrophy of ovary and Fallopian tube	0.697	0.302
K92.1 Melaena	0.697	0.303
T81.3 Disruption of operation wound, not elsewhere classified	0.697	0.303
I64 Stroke, not specified as haemorrhage or infarction	0.696	0.303
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.695	0.304
N32.0 Bladder-neck obstruction	0.695	0.305
N18 Chronic renal failure	0.695	0.305
D64.8 Other specified anaemias	0.694	0.306
D64.4 Congenital dyserythropoietic anaemia	0.694	0.306
D64.3 Other sideroblastic anaemias	0.694	0.306
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.694	0.306
D64.1 Secondary sideroblastic anaemia due to disease	0.694	0.306
D64.0 Hereditary sideroblastic anaemia	0.694	0.306
E40-E46 Malnutrition	0.693	0.306
B25 Cytomegaloviral disease	0.693	0.307
M76 Enthesopathies of lower limb, excluding foot	0.693	0.307
M73 Soft tissue disorders in diseases classified elsewhere	0.693	0.307
M71 Other bursopathies	0.693	0.307
M54 Dorsalgia	0.692	0.308
K93 Disorders of other digestive organs in diseases classified elsewhere	0.691	0.309
M45 Ankylosing spondylitis	0.691	0.309
T87 Complications peculiar to reattachment and amputation	0.690	0.309
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.690	0.309
T80 Complications following infusion, transfusion and therapeutic injection	0.690	0.309
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.690	0.309
I51.4 Myocarditis, unspecified	0.690	0.310
I22 Subsequent myocardial infarction	0.689	0.311
T82.1 Mechanical complication of cardiac electronic device	0.688	0.312
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.688	0.312
K29 Gastritis and duodenitis	0.688	0.312
M48.06 Spinal stenosis (Lumbar region)	0.687	0.313
N99-N99 Other disorders of the genitourinary system	0.686	0.314
K80.2 Calculus of gallbladder without cholecystitis	0.685	0.315
H65 Nonsuppurative otitis media	0.684	0.316
K74 Fibrosis and cirrhosis of liver	0.684	0.316
E27 Other disorders of adrenal gland	0.683	0.317
Chapter XX External causes of morbidity and mortality	0.681	0.319
E11 Non-insulin-dependent diabetes mellitus	0.681	0.319
B99-B99 Other infectious diseases	0.680	0.320
B90-B94 Sequelae of infectious and parasitic diseases	0.680	0.320
B85-B89 Pediculosis, acariasis and other infestations	0.680	0.320
B65-B83 Helminthiases	0.680	0.320
B50-B64 Protozoal diseases	0.680	0.320
B20-B24 Human immunodeficiency virus [HIV] disease	0.680	0.320
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.680	0.320
A80-A89 Viral infections of the central nervous system	0.680	0.320
A75-A79 Rickettsioses	0.680	0.320
A70-A74 Other diseases caused by chlamydiae	0.680	0.320
A65-A69 Other spirochaetal diseases	0.680	0.320
A20-A28 Certain zoonotic bacterial diseases	0.680	0.320
A15-A19 Tuberculosis	0.680	0.320
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.680	0.320
N39.2 Orthostatic proteinuria, unspecified	0.679	0.321
N39.1 Persistent proteinuria, unspecified	0.679	0.321
I73 Other peripheral vascular diseases	0.679	0.321
K43 Ventral hernia	0.678	0.322
B34.9 Viral infection, unspecified	0.678	0.322
S50-S59 Injuries to the elbow and forearm	0.677	0.323
I24 Other acute ischaemic heart diseases	0.677	0.323
Chapter XV Pregnancy, childbirth and the puerperium	0.677	0.323
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.676	0.323
N92.0 Excessive and frequent menstruation with regular cycle	0.675	0.325
I35.9 Aortic valve disorder, unspecified	0.674	0.326
I35.8 Other aortic valve disorders	0.674	0.326
Z01.8 Other specified special examinations	0.674	0.326
I47 Paroxysmal tachycardia	0.672	0.328
K92.9 Disease of digestive system, unspecified	0.672	0.328
R15 Faecal incontinence	0.672	0.328
N95.8 Other specified menopausal and perimenopausal disorders	0.670	0.330
I70 Atherosclerosis	0.670	0.330
M79.9 Soft tissue disorder, unspecified	0.670	0.330
M79.5 Residual foreign body in soft tissue	0.670	0.330
M79.4 Hypertrophy of (infrapatellar) fat pad	0.670	0.330
M79.3 Panniculitis, unspecified	0.670	0.330
M79.2 Neuralgia and neuritis, unspecified	0.670	0.330
M79.1 Myalgia	0.670	0.330
E04.2 Non-toxic multinodular goitre	0.669	0.331
L60-L75 Disorders of skin appendages	0.668	0.331
T81.4 Infection following a procedure, not elsewhere classified	0.667	0.333
R10.0 Acute abdomen	0.667	0.333
M05-M14 Inflammatory polyarthropathies	0.667	0.333
L05 Pilonidal cyst	0.665	0.335
H80-H83 Diseases of inner ear	0.665	0.335
K90.9 Intestinal malabsorption, unspecified	0.664	0.336
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.664	0.336
I83 Varicose veins of lower extremities	0.664	0.336
M24 Other specific joint derangements	0.664	0.336
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.663	0.337
L10-L14 Bullous disorders	0.663	0.337
Z80 Family history of malignant neoplasm	0.663	0.337
M75.3 Calcific tendinitis of shoulder	0.662	0.338
K56.7 Ileus, unspecified	0.662	0.338
C15-C26 Malignant neoplasms of digestive organs	0.662	0.338
D61 Other aplastic anaemias	0.662	0.338
Z03 Medical observation and evaluation for suspected diseases and conditions	0.661	0.339
E66.9 Obesity, unspecified	0.661	0.339
E07 Other disorders of thyroid	0.660	0.339
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.660	0.339
E00 Congenital iodine-deficiency syndrome	0.660	0.339
E02 Subclinical iodine-deficiency hypothyroidism	0.660	0.339
I51.7 Cardiomegaly	0.660	0.340
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.660	0.340
M65 Synovitis and tenosynovitis	0.660	0.340
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.659	0.341
K77 Liver disorders in diseases classified elsewhere	0.658	0.342
K73 Chronic hepatitis, not elsewhere classified	0.658	0.342
K72 Hepatic failure, not elsewhere classified	0.658	0.342
K71 Toxic liver disease	0.658	0.342
N87.2 Severe cervical dysplasia, not elsewhere classified	0.658	0.342
I46 Cardiac arrest	0.658	0.342
R17 Unspecified jaundice	0.657	0.343
M22 Disorders of patella	0.656	0.343
K92.8 Other specified diseases of digestive system	0.656	0.343
I51.9 Heart disease, unspecified	0.655	0.345
R49 Voice disturbances	0.655	0.345
Z97 Presence of other devices	0.655	0.345
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.654	0.346
I72 Other aneurysm	0.654	0.346
M79.69 Pain in limb (Site unspecified)	0.654	0.346
K80.0 Calculus of gallbladder with acute cholecystitis	0.653	0.347
S61 Open wound of wrist and hand	0.653	0.347
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.653	0.347
K90.0 Coeliac disease	0.653	0.347
K57 Diverticular disease of intestine	0.652	0.348
Q00-Q07 Congenital malformations of the nervous system	0.652	0.348
Q21 Congenital malformations of cardiac septa	0.652	0.348
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.651	0.349
R41.3 Other amnesia	0.650	0.350
N75 Diseases of Bartholin's gland	0.649	0.351
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.649	0.351
S79 Other and unspecified injuries of hip and thigh	0.649	0.351
N73 Other female pelvic inflammatory diseases	0.649	0.351
N19 Unspecified renal failure	0.648	0.351
K29.1 Other acute gastritis	0.648	0.352
K37 Unspecified appendicitis	0.648	0.352
Z95.2 Presence of prosthetic heart valve	0.648	0.352
R20 Disturbances of skin sensation	0.647	0.353
M79.68 Pain in limb (Other)	0.646	0.353
M79.64 Pain in limb (Hand)	0.646	0.353
M79.63 Pain in limb (Forearm)	0.646	0.353
M79.62 Pain in limb (Upper arm)	0.646	0.353
M79.61 Pain in limb (Shoulder region)	0.646	0.353
K59.0 Constipation	0.646	0.354
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.645	0.355
I50.1 Left ventricular failure	0.645	0.355
K75.0 Abscess of liver	0.645	0.355
K41 Femoral hernia	0.645	0.355
I44.6 Other and unspecified fascicular block	0.644	0.355
I44.5 Left posterior fascicular block	0.644	0.355
I44.4 Left anterior fascicular block	0.644	0.355
I44.3 Other and unspecified atrioventricular block	0.644	0.355
I44.1 Atrioventricular block, second degree	0.644	0.355
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.644	0.355
Z95.0 Presence of cardiac pacemaker	0.644	0.356
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.642	0.357
M21 Other acquired deformities of limbs	0.642	0.358
M54.9 Dorsalgia, unspecified	0.642	0.358
S64 Injury of nerves at wrist and hand level	0.642	0.358
K55 Vascular disorders of intestine	0.642	0.358
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.642	0.358
I09 Other rheumatic heart diseases	0.641	0.359
I06 Rheumatic aortic valve diseases	0.641	0.359
Z11 Special screening examination for infectious and parasitic diseases	0.641	0.359
Z87 Personal history of other diseases and conditions	0.641	0.359
N17 Acute renal failure	0.641	0.359
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.641	0.359
H94 Other disorders of ear in diseases classified elsewhere	0.641	0.359
L50-L54 Urticaria and erythema	0.640	0.360
K85 Acute pancreatitis	0.640	0.360
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.639	0.360
N76 Other inflammation of vagina and vulva	0.639	0.360
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.639	0.360
N71 Inflammatory disease of uterus, except cervix	0.639	0.360
N70 Salpingitis and oophoritis	0.639	0.360
R90 Abnormal findings on diagnostic imaging of central nervous system	0.639	0.360
R92 Abnormal findings on diagnostic imaging of breast	0.639	0.360
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.639	0.361
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.639	0.361
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.639	0.361
T82.4 Mechanical complication of vascular dialysis catheter	0.639	0.361
T82.3 Mechanical complication of other vascular grafts	0.639	0.361
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.639	0.361
T82.0 Mechanical complication of heart valve prosthesis	0.639	0.361
I71 Aortic aneurysm and dissection	0.639	0.361
I25.6 Silent myocardial ischaemia	0.639	0.361
I25.5 Ischaemic cardiomyopathy	0.639	0.361
I25.4 Coronary artery aneurysm	0.639	0.361
I25.3 Aneurysm of heart	0.639	0.361
I25.0 Atherosclerotic cardiovascular disease, so described	0.639	0.361
S81 Open wound of lower leg	0.639	0.361
M23.4 Loose body in knee	0.637	0.363
K58 Irritable bowel syndrome	0.636	0.364
L80-L99 Other disorders of the skin and subcutaneous tissue	0.636	0.364
R74 Abnormal serum enzyme levels	0.635	0.365
H60-H62 Diseases of external ear	0.635	0.365
N21.0 Calculus in bladder	0.635	0.365
H73 Other disorders of tympanic membrane	0.635	0.365

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations