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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72921303
log Bayes Factor = 15.2522
Chromosome 18   position 44,560,038  (GRCh37) Explore rs72921303 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I25.2 Old myocardial infarction
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.992 0.008 0.000
S50-S59 Injuries to the elbow and forearm
0.989 0.011 0.000
M25 Other joint disorders, not elsewhere classified
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
Chapter I Certain infectious and parasitic diseases
0.981 0.019 0.000
S52 Fracture of forearm
0.976 0.024 0.000
S52.5 Fracture of lower end of radius
0.971 0.029 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.967 0.033 0.000
S52.50 Fracture of lower end of radius (closed)
0.967 0.033 0.000
M25.5 Pain in joint
0.967 0.033 0.000
Chapter XIV Diseases of the genitourinary system
0.964 0.036 0.000
I24 Other acute ischaemic heart diseases
0.962 0.038 0.000
M51 Other intervertebral disk disorders
0.955 0.045 0.000
S80-S89 Injuries to the knee and lower leg
0.954 0.046 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.952 0.048 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.952 0.048 0.000
B95-B98 Bacterial, viral and other infectious agents
0.950 0.050 0.000
Chapter XI Diseases of the digestive system
0.949 0.051 0.000
I25.1 Atherosclerotic heart disease
0.949 0.051 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.948 0.052 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.940 0.060 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.937 0.063 0.000
E70-E90 Metabolic disorders
0.937 0.063 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.936 0.064 0.000
M20 Acquired deformities of fingers and toes
0.935 0.065 0.000
M45-M49 Spondylopathies
0.933 0.067 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.932 0.068 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.930 0.070 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.928 0.072 0.000
R50-R69 General symptoms and signs
0.917 0.083 0.000
Chapter VII Diseases of the eye and adnexa
0.913 0.087 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.911 0.089 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.910 0.090 0.000
N00-N08 Glomerular diseases
0.909 0.091 0.000
M54 Dorsalgia
0.907 0.093 0.000
N99-N99 Other disorders of the genitourinary system
0.902 0.098 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.900 0.100 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.899 0.101 0.000
A00-A09 Intestinal infectious diseases
0.898 0.102 0.000
I21 Acute myocardial infarction
0.892 0.108 0.000
R51 Headache
0.892 0.108 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.889 0.111 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.888 0.112 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.885 0.115 0.000
M23 Internal derangement of knee
0.884 0.116 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.882 0.118 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.881 0.119 0.000
I24.8 Other forms of acute ischaemic heart disease
0.881 0.119 0.000
S80 Superficial injury of lower leg
0.880 0.119 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.869 0.131 0.000
K13 Other diseases of lip and oral mucosa
0.869 0.131 0.000
Chapter VIII Diseases of the ear and mastoid process
0.867 0.133 0.000
M51.2 Other specified intervertebral disk displacement
0.866 0.134 0.000
M47 Spondylosis
0.865 0.135 0.000
M25.8 Other specified joint disorders
0.863 0.137 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.857 0.143 0.000
M50 Cervical disk disorders
0.857 0.143 0.000
M24 Other specific joint derangements
0.853 0.146 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.852 0.148 0.000
I20 Angina pectoris
0.851 0.149 0.000
E87.6 Hypokalaemia
0.849 0.151 0.000
T39.1 4-Aminophenol derivatives
0.845 0.155 0.000
R60 Oedema, not elsewhere classified
0.841 0.159 0.000
D60-D64 Aplastic and other anaemias
0.837 0.163 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.836 0.163 0.000
R21 Rash and other nonspecific skin eruption
0.836 0.164 0.000
M20.2 Hallux rigidus
0.835 0.165 0.000
R41.3 Other amnesia
0.835 0.165 0.000
M21 Other acquired deformities of limbs
0.831 0.169 0.000
Chapter VI Diseases of the nervous system
0.828 0.172 0.000
S80.9 Superficial injury of lower leg, unspecified
0.828 0.172 0.000
Chapter XX External causes of morbidity and mortality
0.827 0.173 0.000
E87.0 Hyperosmolality and hypernatraemia
0.826 0.174 0.000
M51.8 Other specified intervertebral disk disorders
0.826 0.174 0.000
E65-E68 Obesity and other hyperalimentation
0.825 0.175 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.824 0.176 0.000
E87.2 Acidosis
0.824 0.176 0.000
S50 Superficial injury of forearm
0.824 0.176 0.000
N86 Erosion and ectropion of cervix uteri
0.824 0.176 0.000
S70-S79 Injuries to the hip and thigh
0.822 0.178 0.000
K65-K67 Diseases of peritoneum
0.822 0.178 0.000
S90-S99 Injuries to the ankle and foot
0.821 0.178 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.821 0.179 0.000
O36 Maternal care for other known or suspected foetal problems
0.821 0.179 0.000
R40 Somnolence, stupor and coma
0.817 0.183 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.815 0.185 0.000
R45 Symptoms and signs involving emotional state
0.815 0.185 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.814 0.186 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.813 0.187 0.000
K13.0 Diseases of lips
0.813 0.187 0.000
H55-H59 Other disorders of eye and adnexa
0.813 0.187 0.000
D80-D89 Certain disorders involving the immune mechanism
0.813 0.187 0.000
N75 Diseases of Bartholin's gland
0.813 0.187 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.812 0.188 0.000
K02 Dental caries
0.812 0.188 0.000
O60-O75 Complications of labour and delivery
0.811 0.189 0.000
A04 Other bacterial intestinal infections
0.809 0.191 0.000
M20.3 Other deformity of hallux (acquired)
0.809 0.191 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.808 0.192 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.808 0.192 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.808 0.192 0.000
H43-H45 Disorders of vitreous body and globe
0.807 0.193 0.000
M35 Other systemic involvement of connective tissue
0.806 0.194 0.000
S81 Open wound of lower leg
0.806 0.194 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.805 0.195 0.000
N94.1 Dyspareunia
0.805 0.195 0.000
N92 Excessive, frequent and irregular menstruation
0.803 0.197 0.000
N72 Inflammatory disease of cervix uteri
0.803 0.197 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.796 0.204 0.000
E87.5 Hyperkalaemia
0.793 0.207 0.000
M80-M85 Disorders of bone density and structure
0.793 0.207 0.000
M91-M94 Chondropathies
0.793 0.207 0.000
F17.1 Harmful use
0.792 0.208 0.000
K04 Diseases of pulp and periapical tissues
0.789 0.211 0.000
N89 Other noninflammatory disorders of vagina
0.788 0.212 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.788 0.212 0.000
D64 Other anaemias
0.787 0.213 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.787 0.213 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.786 0.214 0.000
H65-H75 Diseases of middle ear and mastoid
0.784 0.216 0.000
K70-K77 Diseases of liver
0.784 0.216 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.783 0.217 0.000
M25.57 Pain in joint (Ankle and foot)
0.783 0.217 0.000
Chapter XXII Codes for special purposes
0.782 0.218 0.000
R52 Pain, not elsewhere classified
0.782 0.218 0.000
R20 Disturbances of skin sensation
0.781 0.219 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.778 0.222 0.000
E88 Other metabolic disorders
0.778 0.222 0.000
A04.8 Other specified bacterial intestinal infections
0.777 0.223 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.774 0.226 0.000
K65 Peritonitis
0.772 0.228 0.000
S40-S49 Injuries to the shoulder and upper arm
0.771 0.228 0.000
M25.52 Pain in joint (Upper arm)
0.771 0.229 0.000
M25.59 Pain in joint (Site unspecified)
0.771 0.229 0.000
M54.9 Dorsalgia, unspecified
0.769 0.231 0.000
N05 Unspecified nephritic syndrome
0.769 0.231 0.000
M25.53 Pain in joint (Forearm)
0.767 0.233 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.767 0.233 0.000
T79-T79 Certain early complications of trauma
0.767 0.233 0.000
H30-H36 Disorders of choroid and retina
0.767 0.233 0.000
A08 Viral and other specified intestinal infections
0.767 0.233 0.000
M23.3 Other meniscus derangements
0.764 0.236 0.000
F41 Other anxiety disorders
0.763 0.237 0.000
N03 Chronic nephritic syndrome
0.763 0.237 0.000
M65-M68 Disorders of synovium and tendon
0.763 0.237 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.763 0.237 0.000
K08 Other disorders of teeth and supporting structures
0.762 0.238 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.761 0.239 0.000
N75.1 Abscess of Bartholin's gland
0.760 0.240 0.000
O42 Premature rupture of membranes
0.760 0.240 0.000
M25.54 Pain in joint (Hand)
0.759 0.241 0.000
B65-B83 Helminthiases
0.757 0.242 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.756 0.244 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.755 0.245 0.000
M45 Ankylosing spondylitis
0.754 0.246 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.753 0.247 0.000
K10 Other diseases of jaws
0.753 0.247 0.000
I20.0 Unstable angina
0.752 0.248 0.000
D64.9 Anaemia, unspecified
0.752 0.248 0.000
M25.50 Pain in joint (Multiple sites)
0.751 0.249 0.000
I25.3 Aneurysm of heart
0.749 0.251 0.000
F99-F99 Unspecified mental disorder
0.749 0.251 0.000
B15-B19 Viral hepatitis
0.749 0.251 0.000
M54.1 Radiculopathy
0.747 0.253 0.000
K50-K52 Noninfective enteritis and colitis
0.747 0.253 0.000
O36.8 Maternal care for other specified foetal problems
0.747 0.253 0.000
F03 Unspecified dementia
0.747 0.253 0.000
M50.0 Cervical disk disorder with myelopathy
0.745 0.255 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
N04 Nephrotic syndrome
0.744 0.256 0.000
D50-D53 Nutritional anaemias
0.744 0.256 0.000
K80 Cholelithiasis
0.744 0.256 0.000
N93 Other abnormal uterine and vaginal bleeding
0.743 0.257 0.000
R59 Enlarged lymph nodes
0.742 0.258 0.000
E85 Amyloidosis
0.742 0.258 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.742 0.258 0.000
H53-H54 Visual disturbances and blindness
0.740 0.260 0.000
N82 Fistulae involving female genital tract
0.739 0.261 0.000
I20.8 Other forms of angina pectoris
0.738 0.262 0.000
O48 Prolonged pregnancy
0.738 0.262 0.000
E87.7 Fluid overload
0.738 0.262 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.737 0.263 0.000
T92 Sequelae of injuries of upper limb
0.735 0.265 0.000
E66 Obesity
0.735 0.265 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.731 0.269 0.000
K75 Other inflammatory liver diseases
0.730 0.270 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.729 0.271 0.000
N87 Dysplasia of cervix uteri
0.729 0.271 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.728 0.271 0.000
M40-M43 Deforming dorsopathies
0.727 0.272 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.727 0.273 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.727 0.273 0.000
F40 Phobic anxiety disorders
0.727 0.273 0.000
M31 Other necrotising vasculopathies
0.726 0.274 0.000
M25.86 Other specified joint disorders (Lower leg)
0.726 0.274 0.000
R23 Other skin changes
0.725 0.275 0.000
K01 Embedded and impacted teeth
0.722 0.278 0.000
R68 Other general symptoms and signs
0.721 0.279 0.000
M20.1 Hallux valgus (acquired)
0.721 0.279 0.000
M47.2 Other spondylosis with radiculopathy
0.720 0.280 0.000
M50.1 Cervical disk disorder with radiculopathy
0.720 0.280 0.000
H66 Suppurative and unspecified otitis media
0.719 0.281 0.000
M24.1 Other articular cartilage disorders
0.719 0.281 0.000
R56 Convulsions, not elsewhere classified
0.718 0.282 0.000
R60.1 Generalised oedema
0.717 0.283 0.000
S82 Fracture of lower leg, including ankle
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.283 0.000
I25.4 Coronary artery aneurysm
0.716 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.283 0.000
S51 Open wound of forearm
0.716 0.284 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
R45.8 Other symptoms and signs involving emotional state
0.713 0.287 0.000
R47-R49 Symptoms and signs involving speech and voice
0.712 0.288 0.000
M53 Other dorsopathies, not elsewhere classified
0.711 0.288 0.000
M47.9 Spondylosis, unspecified
0.711 0.289 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.710 0.290 0.000
S59 Other and unspecified injuries of forearm
0.709 0.291 0.000
S58 Traumatic amputation of forearm
0.709 0.291 0.000
S57 Crushing injury of forearm
0.709 0.291 0.000
S56 Injury of muscle and tendon at forearm level
0.709 0.291 0.000
S55 Injury of blood vessels at forearm level
0.709 0.291 0.000
S54 Injury of nerves at forearm level
0.709 0.291 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.709 0.291 0.000
M25.9 Joint disorder, unspecified
0.709 0.291 0.000
M25.3 Other instability of joint
0.709 0.291 0.000
M25.2 Flail joint
0.709 0.291 0.000
M25.1 Fistula of joint
0.709 0.291 0.000
M25.0 Haemarthrosis
0.709 0.291 0.000
I22 Subsequent myocardial infarction
0.709 0.291 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.707 0.293 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.707 0.293 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.706 0.294 0.000
M47.8 Other spondylosis
0.706 0.294 0.000
I25.5 Ischaemic cardiomyopathy
0.706 0.294 0.000
S50.9 Superficial injury of forearm, unspecified
0.706 0.294 0.000
M20.0 Deformity of finger(s)
0.705 0.295 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.295 0.000
F80-F89 Disorders of psychological development
0.704 0.295 0.000
F70-F79 Mental retardation
0.704 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.295 0.000
M86-M90 Other osteopathies
0.704 0.296 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.704 0.296 0.000
B99-B99 Other infectious diseases
0.704 0.296 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.704 0.296 0.000
B50-B64 Protozoal diseases
0.704 0.296 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A65-A69 Other spirochaetal diseases
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
A15-A19 Tuberculosis
0.704 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
M48 Other spondylopathies
0.702 0.297 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.702 0.298 0.000
K83 Other diseases of biliary tract
0.701 0.298 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.701 0.299 0.000
T93 Sequelae of injuries of lower limb
0.701 0.299 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.701 0.299 0.000
O36.5 Maternal care for poor foetal growth
0.700 0.300 0.000
S52.9 Fracture of forearm, part unspecified
0.700 0.300 0.000
S52.8 Fracture of other parts of forearm
0.700 0.300 0.000
S52.7 Multiple fractures of forearm
0.700 0.300 0.000
S52.4 Fracture of shafts of both ulna and radius
0.700 0.300 0.000
S52.3 Fracture of shaft of radius
0.700 0.300 0.000
S52.2 Fracture of shaft of ulna
0.700 0.300 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.699 0.301 0.000
G30-G32 Other degenerative diseases of the nervous system
0.698 0.302 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.697 0.303 0.000
S52.51 Fracture of lower end of radius (open)
0.696 0.304 0.000
S52.1 Fracture of upper end of radius
0.695 0.304 0.000
K12 Stomatitis and related lesions
0.694 0.306 0.000
R60.0 Localised oedema
0.694 0.306 0.000
F01 Vascular dementia
0.694 0.306 0.000
K51 Ulcerative colitis
0.693 0.307 0.000
M25.58 Pain in joint (Other)
0.693 0.307 0.000
M25.51 Pain in joint (Shoulder region)
0.692 0.307 0.000
H60-H62 Diseases of external ear
0.692 0.308 0.000
N73 Other female pelvic inflammatory diseases
0.692 0.308 0.000
N93.0 Postcoital and contact bleeding
0.691 0.309 0.000
I24.1 Dressler's syndrome
0.690 0.310 0.000
H55 Nystagmus and other irregular eye movements
0.690 0.310 0.000
F41.2 Mixed anxiety and depressive disorder
0.690 0.310 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.690 0.310 0.000
R87 Abnormal findings in specimens from female genital organs
0.688 0.312 0.000
M54.4 Lumbago with sciatica
0.688 0.312 0.000
H43 Disorders of vitreous body
0.687 0.313 0.000
T39.0 Salicylates
0.687 0.313 0.000
D86 Sarcoidosis
0.687 0.313 0.000
M35.7 Hypermobility syndrome
0.686 0.314 0.000
M54.6 Pain in thoracic spine
0.686 0.314 0.000
S20-S29 Injuries to the thorax
0.685 0.315 0.000
M51.3 Other specified intervertebral disk degeneration
0.685 0.315 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.685 0.315 0.000
M51.9 Intervertebral disk disorder, unspecified
0.685 0.315 0.000
M51.4 Schmorl's nodes
0.685 0.315 0.000
M20.5 Other deformities of toe(s) (acquired)
0.684 0.315 0.000
F30-F39 Mood [affective] disorders
0.684 0.316 0.000
T90 Sequelae of injuries of head
0.684 0.316 0.000
S88 Traumatic amputation of lower leg
0.684 0.316 0.000
S87 Crushing injury of lower leg
0.684 0.316 0.000
S86 Injury of muscle and tendon at lower leg level
0.684 0.316 0.000
S85 Injury of blood vessels at lower leg level
0.684 0.316 0.000
S84 Injury of nerves at lower leg level
0.684 0.316 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.684 0.316 0.000
N02 Recurrent and persistent haematuria
0.684 0.316 0.000
K65.9 Peritonitis, unspecified
0.683 0.316 0.000
N99.0 Postprocedural renal failure
0.683 0.317 0.000
E20-E35 Disorders of other endocrine glands
0.683 0.317 0.000
K02.9 Dental caries, unspecified
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.683 0.317 0.000
R07 Pain in throat and chest
0.683 0.317 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.683 0.317 0.000
M54.3 Sciatica
0.682 0.318 0.000
R46 Symptoms and signs involving appearance and behaviour
0.682 0.318 0.000
R43 Disturbances of smell and taste
0.682 0.318 0.000
E40-E46 Malnutrition
0.682 0.318 0.000
O80-O84 Delivery
0.682 0.318 0.000
O43 Placental disorders
0.682 0.318 0.000
M25.4 Effusion of joint
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.681 0.319 0.000
N90.7 Vulvar cyst
0.680 0.320 0.000
O85-O92 Complications predominantly related to the puerperium
0.679 0.320 0.000
F43 Reaction to severe stress, and adjustment disorders
0.679 0.320 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.679 0.321 0.000
K05 Gingivitis and periodontal diseases
0.678 0.322 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.678 0.322 0.000
S81.8 Open wound of other parts of lower leg
0.678 0.322 0.000
O62 Abnormalities of forces of labour
0.677 0.323 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.676 0.324 0.000
R40.2 Coma, unspecified
0.675 0.325 0.000
M05-M14 Inflammatory polyarthropathies
0.675 0.325 0.000
A30-A49 Other bacterial diseases
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
H10-H13 Disorders of conjunctiva
0.675 0.325 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.674 0.326 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.674 0.326 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.674 0.326 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.674 0.326 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.674 0.326 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.674 0.326 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.674 0.326 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.674 0.326 0.000
T36 Poisoning by systemic antibiotics
0.674 0.326 0.000
I21.4 Acute subendocardial myocardial infarction
0.673 0.326 0.000
O44 Placenta praevia
0.673 0.327 0.000
N92.4 Excessive bleeding in the premenopausal period
0.673 0.327 0.000
R41.0 Disorientation, unspecified
0.673 0.327 0.000
R60.9 Oedema, unspecified
0.673 0.327 0.000
K09 Cysts of oral region, not elsewhere classified
0.672 0.328 0.000
K03 Other diseases of hard tissues of teeth
0.672 0.328 0.000
K00 Disorders of tooth development and eruption
0.672 0.328 0.000
E84 Cystic fibrosis
0.671 0.328 0.000
E79 Disorders of purine and pyrimidine metabolism
0.671 0.328 0.000
E77 Disorders of glycoprotein metabolism
0.671 0.328 0.000
E76 Disorders of glycosaminoglycan metabolism
0.671 0.328 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.671 0.328 0.000
E74 Other disorders of carbohydrate metabolism
0.671 0.328 0.000
E73 Lactose intolerance
0.671 0.328 0.000
E72 Other disorders of amino-acid metabolism
0.671 0.328 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.671 0.328 0.000
E70 Disorders of aromatic amino-acid metabolism
0.671 0.328 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.671 0.328 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.671 0.329 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
S92 Fracture of foot, except ankle
0.670 0.329 0.000
T51 Toxic effect of alcohol
0.671 0.329 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.670 0.330 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.670 0.330 0.000
K14 Diseases of tongue
0.670 0.330 0.000
S70 Superficial injury of hip and thigh
0.669 0.331 0.000
M49 Spondylopathies in diseases classified elsewhere
0.669 0.331 0.000
N05.9 Unspecified
0.669 0.331 0.000
M23.8 Other internal derangements of knee
0.668 0.331 0.000
H35 Other retinal disorders
0.668 0.332 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.668 0.332 0.000
H66.9 Otitis media, unspecified
0.668 0.332 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.667 0.333 0.000
E87.4 Mixed disorder of acid-base balance
0.667 0.333 0.000
E87.3 Alkalosis
0.667 0.333 0.000
R06 Abnormalities of breathing
0.667 0.333 0.000
O41 Other disorders of amniotic fluid and membranes
0.666 0.334 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.666 0.334 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.666 0.334 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.666 0.334 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.665 0.335 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.665 0.335 0.000
M47.1 Other spondylosis with myelopathy
0.664 0.336 0.000
K07 Dentofacial anomalies [including malocclusion]
0.664 0.336 0.000
B25-B34 Other viral diseases
0.663 0.337 0.000
K04.8 Radicular cyst
0.663 0.337 0.000
F00 Dementia in Alzheimer's disease
0.663 0.337 0.000
H44 Disorders of globe
0.663 0.337 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.663 0.337 0.000
H34 Retinal vascular occlusions
0.662 0.338 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.662 0.338 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
R40.0 Somnolence
0.660 0.340 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.660 0.340 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.660 0.340 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.659 0.340 0.000
X50-X57 Overexertion, travel and privation
0.659 0.341 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.659 0.341 0.000
N03.9 Unspecified
0.658 0.342 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.658 0.342 0.000
N25-N29 Other disorders of kidney and ureter
0.657 0.343 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.657 0.343 0.000
R62 Lack of expected normal physiological development
0.657 0.343 0.000
R57 Shock, not elsewhere classified
0.657 0.343 0.000
R64 Cachexia
0.657 0.343 0.000
R58 Haemorrhage, not elsewhere classified
0.657 0.343 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.657 0.343 0.000
R26 Abnormalities of gait and mobility
0.657 0.343 0.000
M23.5 Chronic instability of knee
0.656 0.344 0.000
A08.4 Viral intestinal infection, unspecified
0.655 0.345 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.655 0.345 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.654 0.346 0.000
S89 Other and unspecified injuries of lower leg
0.654 0.346 0.000
M35.0 Sicca syndrome [Sjogren]
0.654 0.346 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.653 0.347 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.653 0.347 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.653 0.347 0.000
N71 Inflammatory disease of uterus, except cervix
0.653 0.347 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.653 0.347 0.000
N98 Complications associated with artificial fertilisation
0.653 0.347 0.000
N91 Absent, scanty and rare menstruation
0.653 0.347 0.000
N96 Habitual aborter
0.653 0.347 0.000
N90.4 Leukoplakia of vulva
0.653 0.347 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.652 0.348 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.652 0.348 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.652 0.348 0.000
N06 Isolated proteinuria with specified morphological lesion
0.652 0.348 0.000
N01 Rapidly progressive nephritic syndrome
0.652 0.348 0.000
N00 Acute nephritic syndrome
0.652 0.348 0.000
K02.8 Other dental caries
0.651 0.348 0.000
W00-W19 Falls
0.651 0.349 0.000
M54.8 Other dorsalgia
0.651 0.349 0.000
M54.0 Panniculitis affecting regions of neck and back
0.651 0.349 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.649 0.351 0.000
H90-H95 Other disorders of ear
0.649 0.351 0.000
E86 Volume depletion
0.649 0.351 0.000
N76 Other inflammation of vagina and vulva
0.649 0.351 0.000
M54.2 Cervicalgia
0.647 0.352 0.000
K65.0 Acute peritonitis
0.647 0.352 0.000
G93 Other disorders of brain
0.647 0.353 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.645 0.355 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.645 0.355 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.645 0.355 0.000
T39.4 Antirheumatics, not elsewhere classified
0.645 0.355 0.000
T39.2 Pyrazolone derivatives
0.645 0.355 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.645 0.355 0.000
R41.2 Retrograde amnesia
0.644 0.356 0.000
R41.1 Anterograde amnesia
0.644 0.356 0.000
A07 Other protozoal intestinal diseases
0.644 0.356 0.000
A06 Amoebiasis
0.644 0.356 0.000
A05 Other bacterial foodborne intoxications
0.644 0.356 0.000
A03 Shigellosis
0.644 0.356 0.000
A02 Other Salmonella infections
0.644 0.356 0.000
A01 Typhoid and paratyphoid fevers
0.644 0.356 0.000
A00 Cholera
0.644 0.356 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.644 0.356 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.643 0.357 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.643 0.357 0.000
O66 Other obstructed labour
0.642 0.358 0.000
H71 Cholesteatoma of middle ear
0.642 0.358 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.641 0.359 0.000
K55-K64 Other diseases of intestines
0.641 0.359 0.000
M25.56 Pain in joint (Lower leg)
0.640 0.360 0.000
F17.2 Dependence syndrome
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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