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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73166458
log Bayes Factor = 17.8415
Chromosome 13   position 29,751,732  (GRCh37) Explore rs73166458 on Ensembl!
Variant rs73166458 is part of Cluster X0157

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.991 0.009 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.988 0.012 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.983 0.017 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.981 0.019 0.000
G81 Hemiplegia
0.981 0.019 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.980 0.020 0.000
S61 Open wound of wrist and hand
0.977 0.023 0.000
G81.9 Hemiplegia, unspecified
0.975 0.025 0.000
I69 Sequelae of cerebrovascular disease
0.975 0.025 0.000
G40-G47 Episodic and paroxysmal disorders
0.973 0.027 0.000
Chapter VII Diseases of the eye and adnexa
0.972 0.028 0.000
I63 Cerebral infarction
0.971 0.029 0.000
H30-H36 Disorders of choroid and retina
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
H33 Retinal detachments and breaks
0.964 0.036 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.964 0.036 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.963 0.037 0.000
G40 Epilepsy
0.960 0.040 0.000
B95-B98 Bacterial, viral and other infectious agents
0.959 0.041 0.000
I67 Other cerebrovascular diseases
0.957 0.043 0.000
S61.0 Open wound of finger(s) without damage to nail
0.950 0.050 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.947 0.053 0.000
I26 Pulmonary embolism
0.946 0.054 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.946 0.054 0.000
I63.9 Cerebral infarction, unspecified
0.945 0.055 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.942 0.058 0.000
I67.9 Cerebrovascular disease, unspecified
0.941 0.059 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.940 0.060 0.000
G40.9 Epilepsy, unspecified
0.939 0.061 0.000
T81 Complications of procedures, not elsewhere classified
0.936 0.064 0.000
Chapter X Diseases of the respiratory system
0.931 0.069 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.931 0.069 0.000
H33.0 Retinal detachment with retinal break
0.930 0.070 0.000
E70-E90 Metabolic disorders
0.929 0.071 0.000
A00-A09 Intestinal infectious diseases
0.926 0.074 0.000
M05-M14 Inflammatory polyarthropathies
0.926 0.074 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.921 0.079 0.000
S64 Injury of nerves at wrist and hand level
0.920 0.080 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.920 0.080 0.000
H80-H83 Diseases of inner ear
0.914 0.086 0.000
H90-H95 Other disorders of ear
0.912 0.088 0.000
H33.2 Serous retinal detachment
0.910 0.090 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.909 0.091 0.000
B35-B49 Mycoses
0.906 0.094 0.000
E86 Volume depletion
0.904 0.096 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.903 0.097 0.000
J30-J39 Other diseases of upper respiratory tract
0.903 0.097 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.901 0.099 0.000
S70-S79 Injuries to the hip and thigh
0.900 0.100 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.896 0.104 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.895 0.105 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.894 0.106 0.000
I27 Other pulmonary heart diseases
0.893 0.107 0.000
I61 Intracerebral haemorrhage
0.890 0.110 0.000
J34 Other disorders of nose and nasal sinuses
0.889 0.111 0.000
M80-M85 Disorders of bone density and structure
0.881 0.119 0.000
S10-S19 Injuries to the neck
0.880 0.120 0.000
J09-J18 Influenza and pneumonia
0.878 0.122 0.000
M50-M54 Other dorsopathies
0.877 0.123 0.000
Y42.7 Androgens and anabolic congeners
0.877 0.123 0.000
Y43 Primarily systemic agents
0.877 0.123 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.876 0.124 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.875 0.125 0.000
H60-H62 Diseases of external ear
0.874 0.126 0.000
Chapter V Mental and behavioural disorders
0.872 0.128 0.000
J34.2 Deviated nasal septum
0.871 0.129 0.000
S80-S89 Injuries to the knee and lower leg
0.870 0.130 0.000
X60-X84 Intentional self-harm
0.867 0.133 0.000
M54 Dorsalgia
0.866 0.134 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.866 0.134 0.000
M13 Other arthritis
0.865 0.135 0.000
H81 Disorders of vestibular function
0.864 0.136 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.863 0.137 0.000
O00-O08 Pregnancy with abortive outcome
0.863 0.137 0.000
H92 Otalgia and effusion of ear
0.860 0.140 0.000
T87 Complications peculiar to reattachment and amputation
0.857 0.143 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.855 0.145 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.853 0.147 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.852 0.148 0.000
M86-M90 Other osteopathies
0.849 0.151 0.000
B37 Candidiasis
0.848 0.152 0.000
I30-I52 Other forms of heart disease
0.846 0.154 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.846 0.154 0.000
J39 Other diseases of upper respiratory tract
0.844 0.156 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.844 0.156 0.000
S68 Traumatic amputation of wrist and hand
0.841 0.159 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.839 0.161 0.000
H35 Other retinal disorders
0.838 0.162 0.000
M54.9 Dorsalgia, unspecified
0.835 0.165 0.000
H34 Retinal vascular occlusions
0.833 0.167 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.833 0.167 0.000
H33.3 Retinal breaks without detachment
0.832 0.168 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.830 0.170 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.829 0.171 0.000
H92.1 Otorrhoea
0.829 0.171 0.000
Y83.8 Other surgical procedures
0.826 0.174 0.000
G90-G99 Other disorders of the nervous system
0.825 0.175 0.000
H81.0 Meniere's disease
0.825 0.175 0.000
I05-I09 Chronic rheumatic heart diseases
0.825 0.175 0.000
M40-M43 Deforming dorsopathies
0.825 0.175 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.823 0.176 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.822 0.178 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.822 0.178 0.000
J18 Pneumonia, organism unspecified
0.816 0.184 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.815 0.185 0.000
Q24 Other congenital malformations of heart
0.815 0.185 0.000
S90-S99 Injuries to the ankle and foot
0.814 0.186 0.000
Y42.5 Other oestrogens and progestogens
0.812 0.188 0.000
I62 Other nontraumatic intracranial haemorrhage
0.810 0.190 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.806 0.194 0.000
S61.7 Multiple open wounds of wrist and hand
0.806 0.194 0.000
S64.3 Injury of digital nerve of thumb
0.804 0.196 0.000
H43-H45 Disorders of vitreous body and globe
0.803 0.197 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.801 0.199 0.000
I49 Other cardiac arrhythmias
0.799 0.201 0.000
J90-J94 Other diseases of pleura
0.798 0.202 0.000
Q27 Other congenital malformations of peripheral vascular system
0.797 0.203 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.796 0.204 0.000
F30-F39 Mood [affective] disorders
0.796 0.204 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.794 0.206 0.000
G30-G32 Other degenerative diseases of the nervous system
0.794 0.206 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.793 0.207 0.000
S81 Open wound of lower leg
0.792 0.208 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.792 0.208 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.792 0.208 0.000
M13.9 Arthritis, unspecified
0.791 0.209 0.000
H55-H59 Other disorders of eye and adnexa
0.789 0.211 0.000
V20-V29 Motorcycle rider injured in transport accident
0.788 0.212 0.000
M06 Other rheumatoid arthritis
0.786 0.214 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.786 0.214 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.784 0.216 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.784 0.216 0.000
I51 Complications and ill-defined descriptions of heart disease
0.783 0.217 0.000
S72 Fracture of femur
0.782 0.218 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.782 0.218 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.781 0.219 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.780 0.220 0.000
O04 Medical abortion
0.780 0.220 0.000
E40-E46 Malnutrition
0.776 0.223 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.776 0.224 0.000
J36 Peritonsillar abscess
0.775 0.225 0.000
Y43.3 Other antineoplastic drugs
0.773 0.227 0.000
B50-B64 Protozoal diseases
0.772 0.228 0.000
Y52 Agents primarily affecting the cardiovascular system
0.772 0.228 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.771 0.229 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.771 0.229 0.000
E10-E14 Diabetes mellitus
0.770 0.230 0.000
Q21 Congenital malformations of cardiac septa
0.769 0.231 0.000
A30-A49 Other bacterial diseases
0.769 0.231 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.768 0.232 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.768 0.232 0.000
J39.2 Other diseases of pharynx
0.767 0.233 0.000
B99-B99 Other infectious diseases
0.766 0.234 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.766 0.234 0.000
J90 Pleural effusion, not elsewhere classified
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.765 0.235 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.764 0.236 0.000
S20-S29 Injuries to the thorax
0.762 0.237 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.762 0.238 0.000
I27.9 Pulmonary heart disease, unspecified
0.762 0.238 0.000
Q80-Q89 Other congenital malformations
0.761 0.239 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.761 0.239 0.000
T66-T78 Other and unspecified effects of external causes
0.760 0.240 0.000
M43 Other deforming dorsopathies
0.759 0.241 0.000
S32 Fracture of lumbar spine and pelvis
0.758 0.242 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.758 0.242 0.000
G91 Hydrocephalus
0.757 0.243 0.000
B02 Zoster [herpes zoster]
0.757 0.243 0.000
Q28 Other congenital malformations of circulatory system
0.757 0.243 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.755 0.245 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.755 0.245 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.755 0.245 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.755 0.245 0.000
Q50-Q56 Congenital malformations of genital organs
0.755 0.245 0.000
S65 Injury of blood vessels at wrist and hand level
0.754 0.246 0.000
B15-B19 Viral hepatitis
0.754 0.246 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.753 0.247 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.753 0.247 0.000
M81 Osteoporosis without pathological fracture
0.752 0.248 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.248 0.000
Q23 Congenital malformations of aortic and mitral valves
0.752 0.248 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.752 0.248 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.751 0.248 0.000
A02 Other Salmonella infections
0.750 0.250 0.000
J18.1 Lobar pneumonia, unspecified
0.750 0.250 0.000
S69 Other and unspecified injuries of wrist and hand
0.750 0.250 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.750 0.250 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.748 0.252 0.000
E88 Other metabolic disorders
0.748 0.252 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.747 0.253 0.000
B37.0 Candidal stomatitis
0.747 0.253 0.000
I51.7 Cardiomegaly
0.747 0.253 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.746 0.253 0.000
S19 Other and unspecified injuries of neck
0.746 0.254 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.744 0.256 0.000
M89 Other disorders of bone
0.744 0.256 0.000
X20-X29 Contact with venomous animals and plants
0.743 0.257 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.743 0.257 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.742 0.258 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.742 0.258 0.000
G12 Spinal muscular atrophy and related syndromes
0.740 0.259 0.000
I27.0 Primary pulmonary hypertension
0.740 0.260 0.000
M00-M03 Infectious arthropathies
0.739 0.260 0.000
Y83.4 Other reconstructive surgery
0.738 0.262 0.000
Q00-Q07 Congenital malformations of the nervous system
0.738 0.262 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.738 0.262 0.000
M85 Other disorders of bone density and structure
0.737 0.263 0.000
I49.9 Cardiac arrhythmia, unspecified
0.737 0.263 0.000
G80 Infantile cerebral palsy
0.737 0.263 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.737 0.263 0.000
M91-M94 Chondropathies
0.736 0.264 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.735 0.265 0.000
H60 Otitis externa
0.735 0.265 0.000
T79-T79 Certain early complications of trauma
0.735 0.265 0.000
A80-A89 Viral infections of the central nervous system
0.735 0.265 0.000
Y44 Agents primarily affecting blood constituents
0.735 0.265 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.734 0.266 0.000
O80-O84 Delivery
0.733 0.267 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.732 0.268 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.732 0.268 0.000
S71 Open wound of hip and thigh
0.731 0.269 0.000
I05 Rheumatic mitral valve diseases
0.731 0.269 0.000
O26.8 Other specified pregnancy-related conditions
0.731 0.269 0.000
S72.0 Fracture of neck of femur
0.730 0.270 0.000
X78 Intentional self-harm by sharp object
0.730 0.270 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.730 0.270 0.000
V40-V49 Car occupant injured in transport accident
0.728 0.272 0.000
H61 Other disorders of external ear
0.727 0.272 0.000
T87.4 Infection of amputation stump
0.727 0.273 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.727 0.273 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.727 0.273 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.727 0.273 0.000
H81.2 Vestibular neuronitis
0.724 0.276 0.000
M54.3 Sciatica
0.724 0.276 0.000
G41 Status epilepticus
0.724 0.276 0.000
S31 Open wound of abdomen, lower back and pelvis
0.723 0.277 0.000
M60-M63 Disorders of muscles
0.723 0.277 0.000
H44 Disorders of globe
0.722 0.278 0.000
M13.0 Polyarthritis, unspecified
0.721 0.279 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.720 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
S64.4 Injury of digital nerve of other finger
0.719 0.281 0.000
I27.8 Other specified pulmonary heart diseases
0.719 0.281 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.718 0.282 0.000
E85 Amyloidosis
0.718 0.282 0.000
G82 Paraplegia and tetraplegia
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.717 0.283 0.000
Y45.2 Propionic acid derivatives
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
T90 Sequelae of injuries of head
0.716 0.284 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
J18.0 Bronchopneumonia, unspecified
0.714 0.286 0.000
G58 Other mononeuropathies
0.714 0.286 0.000
J39.8 Other specified diseases of upper respiratory tract
0.714 0.286 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.713 0.287 0.000
M90 Osteopathies in diseases classified elsewhere
0.712 0.288 0.000
M10 Gout
0.711 0.289 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.289 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.289 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.289 0.000
M05 Seropositive rheumatoid arthritis
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
B37.8 Candidiasis of other sites
0.708 0.292 0.000
Y83.0 Surgical operation with transplant of whole organ
0.708 0.292 0.000
M54.1 Radiculopathy
0.708 0.292 0.000
T81.9 Unspecified complication of procedure
0.708 0.292 0.000
Y83.3 Surgical operation with formation of external stoma
0.708 0.292 0.000
G20-G26 Extrapyramidal and movement disorders
0.707 0.293 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.706 0.293 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.706 0.294 0.000
O04.9 Complete or unspecified, without complication
0.705 0.295 0.000
I28 Other diseases of pulmonary vessels
0.705 0.295 0.000
J17 Pneumonia in diseases classified elsewhere
0.704 0.296 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.704 0.296 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.703 0.297 0.000
Q35-Q37 Cleft lip and cleft palate
0.703 0.297 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.703 0.297 0.000
G81.1 Spastic hemiplegia
0.703 0.297 0.000
G81.0 Flaccid hemiplegia
0.703 0.297 0.000
M54.5 Low back pain
0.703 0.297 0.000
H91 Other hearing loss
0.702 0.298 0.000
H34.2 Other retinal artery occlusions
0.701 0.299 0.000
I60 Subarachnoid haemorrhage
0.700 0.300 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.699 0.301 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.699 0.301 0.000
I78 Diseases of capillaries
0.699 0.301 0.000
E13 Other specified diabetes mellitus
0.698 0.302 0.000
M06.9 Rheumatoid arthritis, unspecified
0.698 0.302 0.000
M43.1 Spondylolisthesis
0.698 0.302 0.000
S81.9 Open wound of lower leg, part unspecified
0.698 0.302 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.697 0.303 0.000
G44 Other headache syndromes
0.697 0.303 0.000
Y57 Other and unspecified drugs and medicaments
0.696 0.304 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.696 0.304 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.696 0.304 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.696 0.304 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.696 0.304 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.696 0.304 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.696 0.304 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.696 0.304 0.000
H31 Other disorders of choroid
0.696 0.304 0.000
H30 Chorioretinal inflammation
0.696 0.304 0.000
O20 Haemorrhage in early pregnancy
0.695 0.305 0.000
H65-H75 Diseases of middle ear and mastoid
0.695 0.305 0.000
H35.9 Retinal disorder, unspecified
0.694 0.306 0.000
B25-B34 Other viral diseases
0.693 0.307 0.000
S72.00 Fracture of neck of femur (closed)
0.693 0.307 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.691 0.308 0.000
F33 Recurrent depressive disorder
0.691 0.309 0.000
H33.4 Traction detachment of retina
0.691 0.309 0.000
H33.1 Retinoschisis and retinal cysts
0.691 0.309 0.000
I77 Other disorders of arteries and arterioles
0.691 0.309 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.691 0.309 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.691 0.309 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.691 0.309 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.691 0.309 0.000
Y84.6 Urinary catheterisation
0.691 0.309 0.000
Y42.9 Other and unspecified hormone antagonists
0.690 0.310 0.000
Y42.4 Oral contraceptives
0.690 0.310 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.690 0.310 0.000
Y42.2 Antithyroid drugs
0.690 0.310 0.000
Y42.1 Thyroid hormones and substitutes
0.690 0.310 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
H35.2 Other proliferative retinopathy
0.689 0.311 0.000
B37.1 Pulmonary candidiasis
0.689 0.311 0.000
G40.8 Other epilepsy
0.688 0.311 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.688 0.311 0.000
G40.5 Special epileptic syndromes
0.688 0.311 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.688 0.311 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.688 0.311 0.000
A04 Other bacterial intestinal infections
0.688 0.312 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.688 0.312 0.000
O02 Other abnormal products of conception
0.688 0.312 0.000
F31 Bipolar affective disorder
0.688 0.312 0.000
I07 Rheumatic tricuspid valve diseases
0.687 0.312 0.000
Y84.1 Kidney dialysis
0.687 0.313 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.686 0.314 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.686 0.314 0.000
I67.5 Moyamoya disease
0.686 0.314 0.000
I67.4 Hypertensive encephalopathy
0.686 0.314 0.000
I67.3 Progressive vascular leukoencephalopathy
0.686 0.314 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.686 0.314 0.000
G43 Migraine
0.686 0.314 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.685 0.314 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.685 0.315 0.000
H34.1 Central retinal artery occlusion
0.685 0.315 0.000
Y84.2 Radiological procedure and radiotherapy
0.684 0.316 0.000
B37.3 Candidiasis of vulva and vagina
0.684 0.316 0.000
A49 Bacterial infection of unspecified site
0.684 0.316 0.000
H83 Other diseases of inner ear
0.684 0.316 0.000
S10 Superficial injury of neck
0.684 0.316 0.000
G54 Nerve root and plexus disorders
0.683 0.317 0.000
T87.6 Other and unspecified complications of amputation stump
0.683 0.317 0.000
F80-F89 Disorders of psychological development
0.683 0.317 0.000
I49.4 Other and unspecified premature depolarisation
0.682 0.318 0.000
Y43.4 Immunosuppressive agents
0.680 0.320 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.680 0.320 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.680 0.320 0.000
S91 Open wound of ankle and foot
0.679 0.321 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.679 0.321 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.678 0.322 0.000
Q26 Congenital malformations of great veins
0.678 0.322 0.000
Q25 Congenital malformations of great arteries
0.678 0.322 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.678 0.322 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.678 0.322 0.000
S50-S59 Injuries to the elbow and forearm
0.678 0.322 0.000
J95-J99 Other diseases of the respiratory system
0.678 0.322 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.677 0.323 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.677 0.323 0.000
O00 Ectopic pregnancy
0.677 0.323 0.000
M54.2 Cervicalgia
0.676 0.324 0.000
S67 Crushing injury of wrist and hand
0.676 0.324 0.000
V10-V19 Pedal cyclist injured in transport accident
0.676 0.324 0.000
H35.5 Hereditary retinal dystrophy
0.675 0.325 0.000
Q24.5 Malformation of coronary vessels
0.674 0.326 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.674 0.326 0.000
T86 Failure and rejection of transplanted organs and tissues
0.673 0.327 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.672 0.328 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.671 0.329 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.671 0.329 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.671 0.329 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.670 0.329 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.670 0.330 0.000
I49.5 Sick sinus syndrome
0.670 0.330 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.670 0.330 0.000
I74 Arterial embolism and thrombosis
0.669 0.331 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.668 0.332 0.000
S62 Fracture at wrist and hand level
0.668 0.332 0.000
I67.1 Cerebral aneurysm, nonruptured
0.668 0.332 0.000
G11 Hereditary ataxia
0.667 0.333 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.667 0.333 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.667 0.333 0.000
O28 Abnormal findings on antenatal screening of mother
0.667 0.333 0.000
O23 Infections of genito-urinary tract in pregnancy
0.666 0.333 0.000
G70-G73 Diseases of myoneural junction and muscle
0.666 0.334 0.000
E84 Cystic fibrosis
0.666 0.334 0.000
E79 Disorders of purine and pyrimidine metabolism
0.666 0.334 0.000
E77 Disorders of glycoprotein metabolism
0.666 0.334 0.000
E76 Disorders of glycosaminoglycan metabolism
0.666 0.334 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.666 0.334 0.000
E74 Other disorders of carbohydrate metabolism
0.666 0.334 0.000
E73 Lactose intolerance
0.666 0.334 0.000
E72 Other disorders of amino-acid metabolism
0.666 0.334 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.666 0.334 0.000
E70 Disorders of aromatic amino-acid metabolism
0.666 0.334 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.666 0.334 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.666 0.334 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.666 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
H44.2 Degenerative myopia
0.665 0.335 0.000
S40-S49 Injuries to the shoulder and upper arm
0.665 0.335 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.664 0.336 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.664 0.336 0.000
A07 Other protozoal intestinal diseases
0.664 0.336 0.000
A06 Amoebiasis
0.664 0.336 0.000
A05 Other bacterial foodborne intoxications
0.664 0.336 0.000
A03 Shigellosis
0.664 0.336 0.000
A01 Typhoid and paratyphoid fevers
0.664 0.336 0.000
A00 Cholera
0.664 0.336 0.000
M14 Arthropathies in other diseases classified elsewhere
0.664 0.336 0.000
M12 Other specific arthropathies
0.664 0.336 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.664 0.336 0.000
M08 Juvenile arthritis
0.664 0.336 0.000
S79 Other and unspecified injuries of hip and thigh
0.663 0.337 0.000
Q24.8 Other specified congenital malformations of heart
0.660 0.340 0.000
Y83.5 Amputation of limb(s)
0.660 0.340 0.000
O24 Diabetes mellitus in pregnancy
0.659 0.340 0.000
I71 Aortic aneurysm and dissection
0.659 0.341 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.659 0.341 0.000
S64.8 Injury of other nerves at wrist and hand level
0.659 0.341 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.659 0.341 0.000
S64.1 Injury of median nerve at wrist and hand level
0.659 0.341 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.659 0.341 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.659 0.341 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.659 0.341 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.658 0.342 0.000
E46 Unspecified protein-energy malnutrition
0.658 0.342 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.657 0.343 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.657 0.343 0.000
O21 Excessive vomiting in pregnancy
0.656 0.344 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.656 0.344 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.655 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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