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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73207492
log Bayes Factor = 11.564
Chromosome 13   position 58,334,359  (GRCh37) Explore rs73207492 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.993 0.007 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
M45-M49 Spondylopathies
0.981 0.019 0.000
Chapter VIII Diseases of the ear and mastoid process
0.978 0.022 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.969 0.031 0.000
I60-I69 Cerebrovascular diseases
0.965 0.035 0.000
S60-S69 Injuries to the wrist and hand
0.961 0.039 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.958 0.042 0.000
M20-M25 Other joint disorders
0.954 0.046 0.000
M40-M43 Deforming dorsopathies
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.950 0.050 0.000
M47 Spondylosis
0.944 0.056 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.940 0.060 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.939 0.061 0.000
M25 Other joint disorders, not elsewhere classified
0.937 0.063 0.000
M80-M85 Disorders of bone density and structure
0.934 0.066 0.000
Chapter VI Diseases of the nervous system
0.931 0.069 0.000
T42.4 Benzodiazepines
0.930 0.070 0.000
M25.7 Osteophyte
0.926 0.074 0.000
M86-M90 Other osteopathies
0.925 0.075 0.000
S61 Open wound of wrist and hand
0.916 0.084 0.000
M47.8 Other spondylosis
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.906 0.094 0.000
I67 Other cerebrovascular diseases
0.905 0.095 0.000
I60 Subarachnoid haemorrhage
0.905 0.095 0.000
F60-F69 Disorders of adult personality and behaviour
0.901 0.099 0.000
I05-I09 Chronic rheumatic heart diseases
0.888 0.112 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.888 0.112 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.887 0.113 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.886 0.114 0.000
S10-S19 Injuries to the neck
0.881 0.119 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.878 0.121 0.000
W20-W49 Exposure to inanimate mechanical forces
0.876 0.124 0.000
M25.77 Osteophyte (Ankle and foot)
0.872 0.128 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.869 0.131 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.868 0.132 0.000
M46 Other inflammatory spondylopathies
0.863 0.137 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.862 0.138 0.000
M21 Other acquired deformities of limbs
0.862 0.138 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.861 0.139 0.000
I20-I25 Ischaemic heart diseases
0.861 0.139 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.860 0.140 0.000
M41 Scoliosis
0.860 0.140 0.000
M43 Other deforming dorsopathies
0.857 0.143 0.000
M25.74 Osteophyte (Hand)
0.854 0.146 0.000
W50-W64 Exposure to animate mechanical forces
0.853 0.147 0.000
H80-H83 Diseases of inner ear
0.853 0.147 0.000
H65-H75 Diseases of middle ear and mastoid
0.852 0.148 0.000
M06.0 Seronegative rheumatoid arthritis
0.852 0.148 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.851 0.149 0.000
M05 Seropositive rheumatoid arthritis
0.851 0.149 0.000
Y52 Agents primarily affecting the cardiovascular system
0.850 0.150 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.847 0.153 0.000
H90-H95 Other disorders of ear
0.846 0.154 0.000
M84 Disorders of continuity of bone
0.846 0.154 0.000
X60-X84 Intentional self-harm
0.845 0.154 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.844 0.156 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.842 0.158 0.000
S70-S79 Injuries to the hip and thigh
0.841 0.159 0.000
S40-S49 Injuries to the shoulder and upper arm
0.840 0.160 0.000
F60 Specific personality disorders
0.838 0.162 0.000
S61.0 Open wound of finger(s) without damage to nail
0.838 0.162 0.000
S90-S99 Injuries to the ankle and foot
0.837 0.163 0.000
S65 Injury of blood vessels at wrist and hand level
0.837 0.163 0.000
M81 Osteoporosis without pathological fracture
0.836 0.164 0.000
F17.1 Harmful use
0.836 0.164 0.000
I24 Other acute ischaemic heart diseases
0.834 0.166 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.833 0.167 0.000
M25.76 Osteophyte (Lower leg)
0.833 0.167 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.831 0.169 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.831 0.169 0.000
V40-V49 Car occupant injured in transport accident
0.831 0.169 0.000
O00-O08 Pregnancy with abortive outcome
0.831 0.169 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.829 0.171 0.000
S80-S89 Injuries to the knee and lower leg
0.829 0.171 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.828 0.172 0.000
I67.8 Other specified cerebrovascular diseases
0.823 0.177 0.000
X50-X57 Overexertion, travel and privation
0.823 0.177 0.000
M10 Gout
0.823 0.177 0.000
O26.8 Other specified pregnancy-related conditions
0.820 0.180 0.000
G90-G99 Other disorders of the nervous system
0.819 0.181 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.819 0.181 0.000
H60-H62 Diseases of external ear
0.815 0.185 0.000
M47.86 Other spondylosis (Lumbar region)
0.814 0.186 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.812 0.188 0.000
M48 Other spondylopathies
0.810 0.190 0.000
Y44 Agents primarily affecting blood constituents
0.810 0.190 0.000
M89 Other disorders of bone
0.809 0.191 0.000
M24 Other specific joint derangements
0.805 0.195 0.000
F20 Schizophrenia
0.803 0.197 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.803 0.197 0.000
I74 Arterial embolism and thrombosis
0.803 0.197 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.802 0.198 0.000
I30-I52 Other forms of heart disease
0.798 0.202 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.796 0.204 0.000
M65-M68 Disorders of synovium and tendon
0.795 0.205 0.000
M41.9 Scoliosis, unspecified
0.793 0.207 0.000
M60-M63 Disorders of muscles
0.788 0.212 0.000
G30-G32 Other degenerative diseases of the nervous system
0.785 0.215 0.000
H81 Disorders of vestibular function
0.785 0.215 0.000
I51 Complications and ill-defined descriptions of heart disease
0.784 0.216 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.783 0.217 0.000
S64 Injury of nerves at wrist and hand level
0.783 0.217 0.000
S61.7 Multiple open wounds of wrist and hand
0.782 0.218 0.000
S32 Fracture of lumbar spine and pelvis
0.781 0.219 0.000
M47.9 Spondylosis, unspecified
0.778 0.222 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.778 0.222 0.000
Chapter II Neoplasms
0.777 0.223 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.776 0.224 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.775 0.225 0.000
Y57 Other and unspecified drugs and medicaments
0.773 0.227 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.772 0.228 0.000
H90 Conductive and sensorineural hearing loss
0.772 0.228 0.000
I05 Rheumatic mitral valve diseases
0.772 0.228 0.000
C15-C26 Malignant neoplasms of digestive organs
0.772 0.228 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.771 0.229 0.000
F99-F99 Unspecified mental disorder
0.771 0.229 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.770 0.230 0.000
W00-W19 Falls
0.769 0.231 0.000
M25.8 Other specified joint disorders
0.767 0.233 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.765 0.235 0.000
M86 Osteomyelitis
0.765 0.235 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.763 0.237 0.000
S60 Superficial injury of wrist and hand
0.761 0.239 0.000
I67.1 Cerebral aneurysm, nonruptured
0.761 0.239 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.761 0.239 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.760 0.239 0.000
I77 Other disorders of arteries and arterioles
0.758 0.242 0.000
F20.0 Paranoid schizophrenia
0.756 0.244 0.000
S80 Superficial injury of lower leg
0.755 0.245 0.000
M31 Other necrotising vasculopathies
0.755 0.245 0.000
M13 Other arthritis
0.754 0.246 0.000
M06.3 Rheumatoid nodule
0.754 0.246 0.000
I24.8 Other forms of acute ischaemic heart disease
0.754 0.246 0.000
T91 Sequelae of injuries of neck and trunk
0.754 0.246 0.000
M21.0 Valgus deformity, not elsewhere classified
0.753 0.247 0.000
E20-E35 Disorders of other endocrine glands
0.752 0.248 0.000
I51.7 Cardiomegaly
0.751 0.249 0.000
W25 Contact with sharp glass
0.750 0.250 0.000
W55 Bitten or struck by other mammals
0.749 0.251 0.000
G70-G73 Diseases of myoneural junction and muscle
0.749 0.251 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.748 0.252 0.000
G82 Paraplegia and tetraplegia
0.747 0.253 0.000
M25.0 Haemarthrosis
0.746 0.254 0.000
I95 Hypotension
0.746 0.254 0.000
S12 Fracture of neck
0.745 0.255 0.000
T66-T78 Other and unspecified effects of external causes
0.744 0.255 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.744 0.256 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.744 0.256 0.000
M43.1 Spondylolisthesis
0.743 0.257 0.000
F60.9 Personality disorder, unspecified
0.742 0.257 0.000
T93 Sequelae of injuries of lower limb
0.742 0.258 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.741 0.259 0.000
I50 Heart failure
0.740 0.260 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.739 0.260 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.739 0.261 0.000
O21 Excessive vomiting in pregnancy
0.737 0.263 0.000
H74 Other disorders of middle ear and mastoid
0.737 0.263 0.000
G80 Infantile cerebral palsy
0.735 0.265 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.733 0.267 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.733 0.267 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.733 0.267 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.731 0.269 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.729 0.271 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
F60.3 Emotionally unstable personality disorder
0.728 0.272 0.000
H93 Other disorders of ear, not elsewhere classified
0.728 0.272 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.726 0.274 0.000
M84.0 Malunion of fracture
0.725 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.725 0.275 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.724 0.276 0.000
M34 Systemic sclerosis
0.722 0.278 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.721 0.279 0.000
Y40 Systemic antibiotics
0.720 0.279 0.000
M91-M94 Chondropathies
0.720 0.280 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.720 0.280 0.000
I08 Multiple valve diseases
0.720 0.280 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.719 0.281 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.719 0.281 0.000
S80.9 Superficial injury of lower leg, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
S68 Traumatic amputation of wrist and hand
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.716 0.283 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.716 0.283 0.000
I62 Other nontraumatic intracranial haemorrhage
0.716 0.284 0.000
M81.9 Osteoporosis, unspecified
0.716 0.284 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
M90 Osteopathies in diseases classified elsewhere
0.715 0.285 0.000
E50-E64 Other nutritional deficiencies
0.715 0.285 0.000
I61 Intracerebral haemorrhage
0.714 0.286 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
T36 Poisoning by systemic antibiotics
0.712 0.288 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.712 0.288 0.000
G93 Other disorders of brain
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.710 0.290 0.000
Y44.2 Anticoagulants
0.709 0.291 0.000
M43.0 Spondylolysis
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.708 0.292 0.000
F70-F79 Mental retardation
0.708 0.292 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.708 0.292 0.000
S65.5 Injury of blood vessel(s) of other finger
0.707 0.293 0.000
I25 Chronic ischaemic heart disease
0.707 0.293 0.000
C25 Malignant neoplasm of pancreas
0.707 0.293 0.000
S89 Other and unspecified injuries of lower leg
0.707 0.293 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.706 0.294 0.000
M87 Osteonecrosis
0.705 0.295 0.000
W44 Foreign body entering into or through eye or natural orifice
0.704 0.296 0.000
T92 Sequelae of injuries of upper limb
0.704 0.296 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.704 0.296 0.000
M89.9 Disorder of bone, unspecified
0.704 0.296 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.704 0.296 0.000
O20 Haemorrhage in early pregnancy
0.703 0.297 0.000
M49 Spondylopathies in diseases classified elsewhere
0.703 0.297 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.702 0.298 0.000
O03 Spontaneous abortion
0.702 0.298 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.701 0.299 0.000
E70-E90 Metabolic disorders
0.701 0.299 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
T43.6 Psychostimulants with abuse potential
0.699 0.301 0.000
M67 Other disorders of synovium and tendon
0.699 0.301 0.000
F17.2 Dependence syndrome
0.699 0.301 0.000
O26.9 Pregnancy-related condition, unspecified
0.699 0.301 0.000
O60-O75 Complications of labour and delivery
0.697 0.303 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.697 0.303 0.000
M10.9 Gout, unspecified
0.696 0.304 0.000
Q50-Q56 Congenital malformations of genital organs
0.695 0.305 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.695 0.305 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.695 0.305 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.695 0.305 0.000
T42.3 Barbiturates
0.695 0.305 0.000
T42.2 Succinimides and oxazolidinediones
0.695 0.305 0.000
T42.1 Iminostilbenes
0.695 0.305 0.000
T42.0 Hydantoin derivatives
0.695 0.305 0.000
M48.0 Spinal stenosis
0.693 0.307 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.308 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.308 0.000
G20-G26 Extrapyramidal and movement disorders
0.690 0.310 0.000
S99 Other and unspecified injuries of ankle and foot
0.690 0.310 0.000
H72 Perforation of tympanic membrane
0.690 0.310 0.000
I51.8 Other ill-defined heart diseases
0.690 0.310 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.690 0.310 0.000
S71 Open wound of hip and thigh
0.689 0.311 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.689 0.311 0.000
F10.2 Dependence syndrome
0.688 0.312 0.000
H61 Other disorders of external ear
0.687 0.313 0.000
I05.9 Mitral valve disease, unspecified
0.686 0.314 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.685 0.315 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
G95 Other diseases of spinal cord
0.684 0.316 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.684 0.316 0.000
M33 Dermatopolymyositis
0.684 0.316 0.000
M32 Systemic lupus erythematosus
0.684 0.316 0.000
M30 Polyarteritis nodosa and related conditions
0.684 0.316 0.000
H66 Suppurative and unspecified otitis media
0.684 0.316 0.000
M42 Spinal osteochondrosis
0.683 0.316 0.000
M40 Kyphosis and lordosis
0.683 0.316 0.000
O85-O92 Complications predominantly related to the puerperium
0.682 0.317 0.000
V80-V89 Other land transport accidents
0.681 0.319 0.000
Y59 Other and unspecified vaccines and biological substances
0.681 0.319 0.000
Y58 Bacterial vaccines
0.681 0.319 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.681 0.319 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.681 0.319 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.681 0.319 0.000
Y48 Anaesthetics and therapeutic gases
0.681 0.319 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.681 0.319 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.681 0.319 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.681 0.319 0.000
F50 Eating disorders
0.681 0.319 0.000
S72 Fracture of femur
0.680 0.320 0.000
I51.0 Cardiac septal defect, acquired
0.678 0.322 0.000
O26.2 Pregnancy care of habitual aborter
0.678 0.322 0.000
T51 Toxic effect of alcohol
0.678 0.322 0.000
H90.2 Conductive hearing loss, unspecified
0.678 0.322 0.000
C15 Malignant neoplasm of oesophagus
0.678 0.322 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.677 0.323 0.000
H81.2 Vestibular neuronitis
0.677 0.323 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.677 0.323 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.677 0.323 0.000
Q38.7 Pharyngeal pouch
0.677 0.323 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.677 0.323 0.000
F30-F39 Mood [affective] disorders
0.676 0.324 0.000
L08 Other local infections of skin and subcutaneous tissue
0.675 0.325 0.000
W55.0 Home
0.675 0.325 0.000
E40-E46 Malnutrition
0.675 0.325 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.673 0.327 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.673 0.327 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.673 0.327 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.673 0.327 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.673 0.327 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.673 0.327 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.673 0.327 0.000
F11 Mental and behavioural disorders due to use of opioids
0.673 0.327 0.000
V20-V29 Motorcycle rider injured in transport accident
0.673 0.327 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.673 0.327 0.000
S65.1 Injury of radial artery at wrist and hand level
0.673 0.327 0.000
I44 Atrioventricular and left bundle-branch block
0.673 0.327 0.000
M21.2 Flexion deformity
0.673 0.327 0.000
Q00-Q07 Congenital malformations of the nervous system
0.672 0.328 0.000
M25.2 Flail joint
0.671 0.328 0.000
M25.1 Fistula of joint
0.671 0.328 0.000
I95.2 Hypotension due to drugs
0.671 0.329 0.000
I50.1 Left ventricular failure
0.670 0.330 0.000
M83 Adult osteomalacia
0.670 0.330 0.000
M82 Osteoporosis in diseases classified elsewhere
0.670 0.330 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.670 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.670 0.330 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.669 0.331 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.669 0.331 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.668 0.332 0.000
I60.8 Other subarachnoid haemorrhage
0.668 0.332 0.000
F29 Unspecified nonorganic psychosis
0.667 0.333 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
X78 Intentional self-harm by sharp object
0.667 0.333 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.666 0.334 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.666 0.334 0.000
C16 Malignant neoplasm of stomach
0.665 0.335 0.000
M21.6 Other acquired deformities of ankle and foot
0.665 0.335 0.000
M47.1 Other spondylosis with myelopathy
0.665 0.335 0.000
I50.0 Congestive heart failure
0.665 0.335 0.000
E83 Disorders of mineral metabolism
0.664 0.336 0.000
M81.4 Drug-induced osteoporosis
0.664 0.336 0.000
M25.79 Osteophyte (Site unspecified)
0.664 0.336 0.000
M25.73 Osteophyte (Forearm)
0.664 0.336 0.000
M25.72 Osteophyte (Upper arm)
0.664 0.336 0.000
M25.70 Osteophyte (Multiple sites)
0.664 0.336 0.000
C21 Malignant neoplasm of anus and anal canal
0.664 0.336 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.662 0.338 0.000
C51-C58 Malignant neoplasms of female genital organs
0.662 0.338 0.000
X50 Overexertion and strenuous or repetitive movements
0.662 0.338 0.000
T91.3 Sequelae of injury of spinal cord
0.661 0.339 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.660 0.340 0.000
W25.9 Unspecified place
0.660 0.340 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.660 0.340 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.660 0.340 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.659 0.341 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.659 0.341 0.000
G12 Spinal muscular atrophy and related syndromes
0.658 0.342 0.000
S91 Open wound of ankle and foot
0.657 0.343 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.657 0.343 0.000
G80.9 Infantile cerebral palsy, unspecified
0.657 0.343 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.656 0.344 0.000
M11 Other crystal arthropathies
0.656 0.344 0.000
F80-F89 Disorders of psychological development
0.656 0.344 0.000
I10-I15 Hypertensive diseases
0.655 0.345 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.654 0.345 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.654 0.345 0.000
M47.84 Other spondylosis (Thoracic region)
0.654 0.345 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.654 0.345 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.654 0.345 0.000
V10-V19 Pedal cyclist injured in transport accident
0.654 0.346 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.654 0.346 0.000
S10 Superficial injury of neck
0.654 0.346 0.000
G93.9 Disorder of brain, unspecified
0.653 0.347 0.000
W29 Contact with other powered hand tools and household machinery
0.653 0.347 0.000
M25.3 Other instability of joint
0.653 0.347 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.652 0.348 0.000
H73 Other disorders of tympanic membrane
0.652 0.348 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.652 0.348 0.000
Y60.0 During surgical operation
0.652 0.348 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.651 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
Q80-Q89 Other congenital malformations
0.651 0.349 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.650 0.349 0.000
M86.9 Osteomyelitis, unspecified
0.650 0.350 0.000
S20-S29 Injuries to the thorax
0.650 0.350 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.650 0.350 0.000
Y57.9 Drug or medicament, unspecified
0.650 0.350 0.000
M25.9 Joint disorder, unspecified
0.649 0.351 0.000
O29 Complications of anaesthesia during pregnancy
0.649 0.351 0.000
O28 Abnormal findings on antenatal screening of mother
0.649 0.351 0.000
O22 Venous complications in pregnancy
0.649 0.351 0.000
O25 Malnutrition in pregnancy
0.649 0.351 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.649 0.351 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.649 0.351 0.000
I67.5 Moyamoya disease
0.649 0.351 0.000
I67.4 Hypertensive encephalopathy
0.649 0.351 0.000
I67.3 Progressive vascular leukoencephalopathy
0.649 0.351 0.000
H81.0 Meniere's disease
0.649 0.351 0.000
V48 Car occupant injured in noncollision transport accident
0.649 0.351 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.648 0.351 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.648 0.351 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.648 0.351 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.648 0.351 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.648 0.351 0.000
O00 Ectopic pregnancy
0.648 0.352 0.000
C25.0 Head of pancreas
0.648 0.352 0.000
G82.2 Paraplegia, unspecified
0.648 0.352 0.000
M21.1 Varus deformity, not elsewhere classified
0.647 0.353 0.000
I07 Rheumatic tricuspid valve diseases
0.647 0.353 0.000
H80 Otosclerosis
0.647 0.353 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.647 0.353 0.000
M24.0 Loose body in joint
0.647 0.353 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.646 0.354 0.000
T79-T79 Certain early complications of trauma
0.646 0.354 0.000
F68 Other disorders of adult personality and behaviour
0.646 0.354 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.646 0.354 0.000
F65 Disorders of sexual preference
0.646 0.354 0.000
F64 Gender identity disorders
0.646 0.354 0.000
F63 Habit and impulse disorders
0.646 0.354 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.646 0.354 0.000
F69 Unspecified disorder of adult personality and behaviour
0.646 0.354 0.000
F61 Mixed and other personality disorders
0.646 0.354 0.000
M81.2 Osteoporosis of disuse
0.645 0.355 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.645 0.355 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.645 0.355 0.000
O04 Medical abortion
0.644 0.356 0.000
I69 Sequelae of cerebrovascular disease
0.644 0.356 0.000
E83.1 Disorders of iron metabolism
0.643 0.357 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.643 0.357 0.000
S32.1 Fracture of sacrum
0.643 0.357 0.000
H93.1 Tinnitus
0.643 0.357 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.642 0.358 0.000
E55 Vitamin D deficiency
0.642 0.358 0.000
X51 Travel and motion
0.641 0.358 0.000
T59 Toxic effect of other gases, fumes and vapours
0.639 0.360 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.639 0.361 0.000
M25.71 Osteophyte (Shoulder region)
0.639 0.361 0.000
W13 Fall from, out of or through building or structure
0.638 0.362 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.638 0.362 0.000
I09 Other rheumatic heart diseases
0.637 0.363 0.000
I06 Rheumatic aortic valve diseases
0.637 0.363 0.000
T98 Sequelae of other and unspecified effects of external causes
0.636 0.364 0.000
T95 Sequelae of burns, corrosions and frostbite
0.636 0.364 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.636 0.364 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.636 0.364 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.636 0.364 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.636 0.364 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.636 0.364 0.000
F17.9 Unspecified mental and behavioural disorder
0.636 0.364 0.000
F17.8 Other mental and behavioural disorders
0.636 0.364 0.000
F17.7 Residual and late-onset psychotic disorder
0.636 0.364 0.000
F17.6 Amnesic syndrome
0.636 0.364 0.000
F17.5 Psychotic disorder
0.636 0.364 0.000
F17.4 Withdrawal state with delirium
0.636 0.364 0.000
F17.3 Withdrawal state
0.636 0.364 0.000
F17.0 Acute intoxication
0.636 0.364 0.000
I38 Endocarditis, valve unspecified
0.635 0.365 0.000
M62 Other disorders of muscle
0.635 0.365 0.000
M07 Psoriatic and enteropathic arthropathies
0.635 0.365 0.000
T40.4 Other synthetic narcotics
0.635 0.365 0.000
M25.86 Other specified joint disorders (Lower leg)
0.634 0.366 0.000
Y60.4 During endoscopic examination
0.633 0.367 0.000
S19 Other and unspecified injuries of neck
0.633 0.367 0.000
S50-S59 Injuries to the elbow and forearm
0.633 0.367 0.000
I77.1 Stricture of artery
0.633 0.367 0.000
S17 Crushing injury of neck
0.632 0.368 0.000
S15 Injury of blood vessels at neck level
0.632 0.368 0.000
S14 Injury of nerves and spinal cord at neck level
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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