TreeWAS – Variant ID: rs732998

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.002	0.998
I25.1 Atherosclerotic heart disease	0.000	0.003	0.997
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.005	0.995
I25.2 Old myocardial infarction	0.000	0.009	0.991
I24 Other acute ischaemic heart diseases	0.000	0.039	0.961
I21 Acute myocardial infarction	0.000	0.057	0.943
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.116	0.884
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.116	0.884
I21.4 Acute subendocardial myocardial infarction	0.000	0.145	0.855
I24.8 Other forms of acute ischaemic heart disease	0.000	0.155	0.845
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.162	0.838
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.187	0.813
I20.1 Angina pectoris with documented spasm	0.000	0.200	0.800
I22 Subsequent myocardial infarction	0.000	0.201	0.799
I25.4 Coronary artery aneurysm	0.000	0.238	0.762
I10-I15 Hypertensive diseases	0.000	0.265	0.735
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.000	0.293	0.707
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.301	0.699
I24.1 Dressler's syndrome	0.000	0.311	0.689
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.324	0.676
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.325	0.675
I25.5 Ischaemic cardiomyopathy	0.000	0.327	0.672
I23 Certain current complications following acute myocardial infarction	0.000	0.356	0.644
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.363	0.637
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.384	0.616
Chapter IX Diseases of the circulatory system	0.000	0.404	0.596
I22.8 Subsequent myocardial infarction of other sites	0.000	0.407	0.593
I15 Secondary hypertension	0.000	0.412	0.588
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.452	0.548
I13 Hypertensive heart and renal disease	0.000	0.473	0.527
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.477	0.523
I21.9 Acute myocardial infarction, unspecified	0.000	0.477	0.523
I15.1 Hypertension secondary to other renal disorders	0.000	0.517	0.483
I11 Hypertensive heart disease	0.000	0.525	0.475
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.538	0.462
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.462
I20.8 Other forms of angina pectoris	0.000	0.547	0.453
I00-I02 Acute rheumatic fever	0.000	0.573	0.427
I15.9 Seconday hypertension, unspecified	0.000	0.578	0.422
I15.8 Other secondary hypertension	0.000	0.578	0.422
I15.2 Hypertension secondary to endocrine disorders	0.000	0.578	0.422
I15.0 Renovascular hypertension	0.000	0.578	0.422
I12 Hypertensive renal disease	0.000	0.586	0.414
I23.8 Other current complications following acute myocardial infarction	0.000	0.611	0.388
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.622	0.378
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.622	0.378
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.622	0.378
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.622	0.378
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.670	0.330
I02 Rheumatic chorea	0.000	0.693	0.306
I01 Rheumatic fever with heart involvement	0.000	0.693	0.306
I00 Rheumatic fever without mention of heart involvement	0.000	0.693	0.306
I12.9 Hypertensive renal disease without renal failure	0.000	0.694	0.306
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.697	0.303
I60-I69 Cerebrovascular diseases	0.000	0.714	0.286
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.719	0.281
I99 Other and unspecified disorders of circulatory system	0.000	0.767	0.232
I62 Other nontraumatic intracranial haemorrhage	0.000	0.771	0.229
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.779	0.221
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.780	0.220
I01.8 Other acute rheumatic heart disease	0.000	0.780	0.220
I01.2 Acute rheumatic myocarditis	0.000	0.780	0.220
I01.1 Acute rheumatic endocarditis	0.000	0.780	0.220
I01.0 Acute rheumatic pericarditis	0.000	0.780	0.220
I02.9 Rheumatic chorea without heart involvement	0.000	0.780	0.220
I02.0 Rheumatic chorea with heart involvement	0.000	0.780	0.220
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.780	0.220
I69 Sequelae of cerebrovascular disease	0.000	0.783	0.217
I63 Cerebral infarction	0.000	0.788	0.212
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.795	0.205
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.796	0.204
I60 Subarachnoid haemorrhage	0.000	0.812	0.188
I65.2 Occlusion and stenosis of carotid artery	0.000	0.813	0.186
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.814	0.186
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.819	0.181
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.826	0.174
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.827	0.173
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.828	0.172
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.828	0.171
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.831	0.169
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.832	0.168
I62.1 Nontraumatic extradural haemorrhage	0.000	0.835	0.164
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.835	0.165
I69.3 Sequelae of cerebral infarction	0.000	0.835	0.164
I12.0 Hypertensive renal disease with renal failure	0.000	0.836	0.164
K30 Dyspepsia	0.000	0.838	0.162
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.838	0.161
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.841	0.159
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.841	0.159
I65.1 Occlusion and stenosis of basilar artery	0.000	0.841	0.159
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.841	0.159
I05-I09 Chronic rheumatic heart diseases	0.001	0.841	0.158
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.843	0.156
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.844	0.156
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.844	0.156
I63.8 Other cerebral infarction	0.000	0.844	0.156
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.847	0.153
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.848	0.152
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.848	0.152
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.848	0.152
I60.8 Other subarachnoid haemorrhage	0.000	0.848	0.152
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.852	0.147
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.852	0.147
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.852	0.147
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.852	0.147
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.852	0.147
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.852	0.147
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.852	0.147
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.853	0.147
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.853	0.146
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.853	0.146
I98.0 Cardiovascular syphilis	0.000	0.853	0.146
I67 Other cerebrovascular diseases	0.000	0.857	0.143
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.861	0.138
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.862	0.138
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.862	0.138
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.865	0.135
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.865	0.135
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.865	0.135
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.000	0.866	0.134
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.870	0.130
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.870	0.130
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.870	0.130
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.870	0.130
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.875	0.125
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.877	0.122
I67.1 Cerebral aneurysm, nonruptured	0.000	0.881	0.119
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.882	0.118
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.883	0.117
I06 Rheumatic aortic valve diseases	0.001	0.886	0.113
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.888	0.112
I97.0 Postcardiotomy syndrome	0.000	0.888	0.112
I67.2 Cerebral atherosclerosis	0.000	0.888	0.112
I09 Other rheumatic heart diseases	0.001	0.889	0.111
I68.0 Cerebral amyloid angiopathy	0.000	0.894	0.106
I28 Other diseases of pulmonary vessels	0.001	0.894	0.105
I07 Rheumatic tricuspid valve diseases	0.001	0.896	0.103
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.898	0.102
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.898	0.102
I67.5 Moyamoya disease	0.000	0.898	0.102
I67.4 Hypertensive encephalopathy	0.000	0.898	0.102
I67.3 Progressive vascular leukoencephalopathy	0.000	0.898	0.102
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.898	0.102
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.909	0.091
I97.1 Other functional disturbances following cardiac surgery	0.001	0.909	0.090
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.913	0.086
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.918	0.081
I06.8 Other rheumatic aortic valve diseases	0.001	0.918	0.081
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.918	0.081
I06.1 Rheumatic aortic insufficiency	0.001	0.918	0.081
I06.0 Rheumatic aortic stenosis	0.001	0.918	0.081
I09.8 Other specified rheumatic heart diseases	0.001	0.920	0.079
I09.2 Chronic rheumatic pericarditis	0.001	0.920	0.079
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.920	0.079
I09.0 Rheumatic myocarditis	0.001	0.920	0.079
I09.9 Rheumatic heart disease, unspecified	0.001	0.923	0.076
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.924	0.076
I28.1 Aneurysm of pulmonary artery	0.001	0.924	0.076
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.924	0.076
I07.9 Tricuspid valve disease, unspecified	0.001	0.925	0.074
I07.8 Other tricuspid valve diseases	0.001	0.925	0.074
I07.2 Tricuspid stenosis with insufficiency	0.001	0.925	0.074
I07.0 Tricuspid stenosis	0.001	0.925	0.074
I27 Other pulmonary heart diseases	0.001	0.927	0.073
I05 Rheumatic mitral valve diseases	0.001	0.927	0.072
I61 Intracerebral haemorrhage	0.002	0.931	0.067
I07.1 Tricuspid insufficiency	0.001	0.936	0.064
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.938	0.062
I26 Pulmonary embolism	0.001	0.939	0.061
I28.8 Other specified diseases of pulmonary vessels	0.001	0.941	0.058
I27.8 Other specified pulmonary heart diseases	0.001	0.947	0.053
I27.1 Kyphoscoliotic heart disease	0.001	0.947	0.052
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.948	0.051
I05.8 Other mitral valve diseases	0.001	0.948	0.051
I05.1 Rheumatic mitral insufficiency	0.001	0.948	0.051
I27.0 Primary pulmonary hypertension	0.000	0.949	0.051
I67.9 Cerebrovascular disease, unspecified	0.000	0.949	0.050
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.950	0.048
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.951	0.048
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.951	0.049
I05.9 Mitral valve disease, unspecified	0.001	0.951	0.048
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.952	0.046
I61.8 Other intracerebral haemorrhage	0.002	0.954	0.045
I27.9 Pulmonary heart disease, unspecified	0.001	0.954	0.046
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.954	0.044
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.955	0.044
M20.1 Hallux valgus (acquired)	0.045	0.955	0.000
K21 Gastro-oesophageal reflux disease	0.000	0.956	0.044
R07.4 Chest pain, unspecified	0.000	0.957	0.043
I05.2 Mitral stenosis with insufficiency	0.001	0.958	0.041
I77 Other disorders of arteries and arterioles	0.000	0.958	0.042
I67.8 Other specified cerebrovascular diseases	0.000	0.958	0.042
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.960	0.040
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.962	0.037
I05.0 Mitral stenosis	0.001	0.963	0.036
I95 Hypotension	0.001	0.963	0.036
I72 Other aneurysm	0.000	0.964	0.036
I71 Aortic aneurysm and dissection	0.000	0.964	0.036
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.965	0.035
I79.1 Aortitis in diseases classified elsewhere	0.000	0.965	0.035
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.965	0.035
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.965	0.033
I08 Multiple valve diseases	0.001	0.965	0.034
I70 Atherosclerosis	0.000	0.965	0.035
I77.1 Stricture of artery	0.000	0.966	0.034
I74 Arterial embolism and thrombosis	0.000	0.967	0.033
I78 Diseases of capillaries	0.000	0.967	0.033
I63.9 Cerebral infarction, unspecified	0.000	0.968	0.032
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.969	0.031
I77.5 Necrosis of artery	0.000	0.970	0.030
I77.4 Coeliac artery compression syndrome	0.000	0.970	0.030
I77.3 Arterial fibromuscular dysplasia	0.000	0.970	0.030
I77.2 Rupture of artery	0.000	0.970	0.030
I77.6 Arteritis, unspecified	0.000	0.971	0.029
I72.0 Aneurysm of carotid artery	0.000	0.971	0.029
I74.5 Embolism and thrombosis of iliac artery	0.000	0.972	0.028
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.972	0.028
I71.0 Dissection of aorta [any part]	0.000	0.973	0.027
I72.8 Aneurysm of other specified arteries	0.000	0.973	0.027
I95.8 Other hypotension	0.001	0.973	0.026
I95.0 Idiopathic hypotension	0.001	0.974	0.026
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.974	0.026
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.974	0.026
I72.2 Aneurysm of renal artery	0.000	0.974	0.026
I72.1 Aneurysm of artery of upper extremity	0.000	0.974	0.026
I77.8 Other specified disorders of arteries and arterioles	0.000	0.974	0.026
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.974	0.026
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.974	0.026
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.974	0.026
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.974	0.026
I77.0 Arteriovenous fistula, acquired	0.000	0.974	0.026
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.974	0.025
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.974	0.026
I08.9 Multiple valve disease, unspecified	0.001	0.974	0.025
I70.9 Generalised and unspecified atherosclerosis	0.000	0.975	0.025
I70.8 Atherosclerosis of other arteries	0.000	0.975	0.025
I70.1 Atherosclerosis of renal artery	0.000	0.975	0.024
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.976	0.024
I72.4 Aneurysm of artery of lower extremity	0.000	0.976	0.024
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.976	0.024
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.976	0.024
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.976	0.024
I78.9 Disease of capillaries, unspecified	0.000	0.976	0.024
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.976	0.024
I08.8 Other multiple valve diseases	0.001	0.976	0.023
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.976	0.023
I78.8 Other diseases of capillaries	0.000	0.976	0.023
I72.9 Aneurysm of unspecified site	0.000	0.977	0.023
I74.8 Embolism and thrombosis of other arteries	0.000	0.977	0.023
I70.0 Atherosclerosis of aorta	0.000	0.977	0.023
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.977	0.022
I27.2 Other secondary pulmonary hypertension	0.001	0.978	0.021
K27 Peptic ulcer, site unspecified	0.000	0.979	0.021
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.979	0.021
I08.1 Disorders of both mitral and tricuspid valves	0.001	0.979	0.021
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.980	0.020
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.981	0.019
I95.2 Hypotension due to drugs	0.001	0.981	0.019
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.981	0.018
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.981	0.019
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.981	0.018
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.981	0.018
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.981	0.018
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.981	0.018
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.982	0.018
K28 Gastrojejunal ulcer	0.000	0.982	0.018
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.982	0.018
I30-I52 Other forms of heart disease	0.000	0.982	0.018
I45 Other conduction disorders	0.000	0.983	0.017
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.983	0.017
I45.1 Other and unspecified right bundle-branch block	0.000	0.983	0.017
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.983	0.016
I72.3 Aneurysm of iliac artery	0.001	0.983	0.016
K62.0 Anal polyp	0.016	0.984	0.000
I78.1 Naevus, nonneoplastic	0.000	0.984	0.016
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.984	0.013
M25.46 Effusion of joint (Lower leg)	0.016	0.984	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.984	0.015
I44 Atrioventricular and left bundle-branch block	0.000	0.984	0.016
K27.7 Chronic without haemorrhage or perforation	0.000	0.984	0.015
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.984	0.015
K27.5 Chronic or unspecified with perforation	0.000	0.984	0.015
K27.4 Chronic or unspecified with haemorrhage	0.000	0.984	0.015
K27.3 Acute without haemorrhage or perforation	0.000	0.984	0.015
K27.2 Acute with both haemorrhage and perforation	0.000	0.984	0.015
K27.1 Acute with perforation	0.000	0.984	0.015
K27.0 Acute with haemorrhage	0.000	0.984	0.015
I44.1 Atrioventricular block, second degree	0.000	0.985	0.015
R07 Pain in throat and chest	0.000	0.985	0.015
I44.7 Left bundle-branch block, unspecified	0.000	0.985	0.015
K26 Duodenal ulcer	0.000	0.986	0.014
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.986	0.014
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.986	0.014
I73 Other peripheral vascular diseases	0.000	0.986	0.014
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.000	0.986	0.013
K23.1 Megaoesophagus in Chagas' disease	0.000	0.986	0.013
K23.0 Tuberculous oesophagitis	0.000	0.986	0.013
I37 Pulmonary valve disorders	0.000	0.986	0.013
I50 Heart failure	0.000	0.986	0.014
I45.6 Preexcitation syndrome	0.000	0.986	0.013
I50.1 Left ventricular failure	0.000	0.987	0.013
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.987	0.013
I45.3 Trifascicular block	0.000	0.987	0.013
K26.3 Acute without haemorrhage or perforation	0.000	0.987	0.013
K28.7 Chronic without haemorrhage or perforation	0.000	0.987	0.013
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.987	0.013
K28.5 Chronic or unspecified with perforation	0.000	0.987	0.013
K28.4 Chronic or unspecified with haemorrhage	0.000	0.987	0.013
K28.3 Acute without haemorrhage or perforation	0.000	0.987	0.013
K28.2 Acute with both haemorrhage and perforation	0.000	0.987	0.013
K28.1 Acute with perforation	0.000	0.987	0.013
K28.0 Acute with haemorrhage	0.000	0.987	0.013
I36 Nonrheumatic tricuspid valve disorders	0.000	0.987	0.013
I52 Other heart disorders in diseases classified elsewhere	0.000	0.987	0.013
I48 Atrial fibrillation and flutter	0.000	0.987	0.013
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.987	0.013
I41 Myocarditis in diseases classified elsewhere	0.000	0.987	0.013
I40 Acute myocarditis	0.000	0.987	0.013
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.987	0.013
I32 Pericarditis in diseases classified elsewhere	0.000	0.987	0.013
I45.9 Conduction disorder, unspecified	0.000	0.987	0.013
I45.8 Other specified conduction disorders	0.000	0.987	0.013
I45.2 Bifascicular block	0.000	0.987	0.013
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.987	0.012
I45.0 Right fascicular block	0.000	0.987	0.012
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.987	0.012
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.012	0.988	0.000
I45.4 Nonspecific intraventricular block	0.000	0.988	0.012
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.988	0.012
Z95.1 Presence of aortocoronary bypass graft	0.000	0.988	0.012
I46 Cardiac arrest	0.000	0.988	0.012
I44.5 Left posterior fascicular block	0.000	0.988	0.011
I49 Other cardiac arrhythmias	0.000	0.988	0.012
I44.6 Other and unspecified fascicular block	0.000	0.988	0.011
R07.0 Pain in throat	0.000	0.989	0.011
R07.3 Other chest pain	0.000	0.989	0.011
K26.5 Chronic or unspecified with perforation	0.000	0.989	0.011
I33 Acute and subacute endocarditis	0.000	0.989	0.011
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.011	0.989	0.000
I38 Endocarditis, valve unspecified	0.000	0.989	0.011
R07.2 Precordial pain	0.000	0.989	0.011
I44.3 Other and unspecified atrioventricular block	0.000	0.989	0.011
I45.5 Other specified heart block	0.000	0.989	0.011
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.011	0.989	0.000
M20 Acquired deformities of fingers and toes	0.011	0.989	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.989	0.010
K26.2 Acute with both haemorrhage and perforation	0.000	0.989	0.010
I37.1 Pulmonary valve insufficiency	0.000	0.989	0.010
I49.0 Ventricular fibrillation and flutter	0.000	0.989	0.010
K26.7 Chronic without haemorrhage or perforation	0.000	0.989	0.010
I30 Acute pericarditis	0.000	0.990	0.010
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.990	0.010
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.990	0.010
I37.9 Pulmonary valve disorder, unspecified	0.000	0.990	0.010
I37.8 Other pulmonary valve disorders	0.000	0.990	0.010
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.990	0.010
I37.0 Pulmonary valve stenosis	0.000	0.990	0.010
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.010	0.990	0.000
I44.2 Atrioventricular block, complete	0.000	0.990	0.010
Z95.3 Presence of xenogenic heart valve	0.000	0.990	0.010
K26.0 Acute with haemorrhage	0.000	0.990	0.010
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.990	0.010
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.990	0.009
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.990	0.009
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.990	0.009
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.990	0.009
I44.0 Atrioventricular block, first degree	0.000	0.990	0.010
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.990	0.009
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.990	0.009
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.990	0.009
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.990	0.009
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.990	0.009
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.990	0.009
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.990	0.009
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.990	0.009
I40.9 Acute myocarditis, unspecified	0.000	0.990	0.009
I40.8 Other acute myocarditis	0.000	0.990	0.009
I40.1 Isolated myocarditis	0.000	0.990	0.009
I40.0 Infective myocarditis	0.000	0.990	0.009
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.990	0.009
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.990	0.009
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.990	0.009
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.990	0.009
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.990	0.009
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.990	0.009
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.990	0.009
I48.4 Atypical atrial flutter	0.000	0.990	0.009
I48.3 Typical atrial flutter	0.000	0.990	0.009
I48.2 Chronic atrial fibrillation	0.000	0.990	0.009
I48.1 Persistent atrial fibrillation	0.000	0.990	0.009
I48.0 Paroxysmal atrial fibrillation	0.000	0.990	0.009
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.990	0.009
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.990	0.009
K26.1 Acute with perforation	0.000	0.990	0.009
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.009	0.991	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.009	0.991	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.991	0.009
M65.9 Synovitis and tenosynovitis, unspecified	0.009	0.991	0.000
I44.4 Left anterior fascicular block	0.000	0.991	0.009
I49.9 Cardiac arrhythmia, unspecified	0.000	0.991	0.009
I46.0 Cardiac arrest with successful resuscitation	0.000	0.991	0.009
I46.1 Sudden cardiac death, so described	0.000	0.991	0.009
M20.3 Other deformity of hallux (acquired)	0.009	0.991	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.991	0.009
I49.2 Junctional premature depolarisation	0.000	0.991	0.008
I35 Nonrheumatic aortic valve disorders	0.000	0.991	0.009
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.008	0.992	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.992	0.008
I33.9 Acute endocarditis, unspecified	0.000	0.992	0.008
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.008	0.992	0.000
I31 Other diseases of pericardium	0.000	0.992	0.008
Z95.2 Presence of prosthetic heart valve	0.000	0.992	0.008
I08.0 Disorders of both mitral and aortic valves	0.002	0.992	0.006
I49.8 Other specified cardiac arrhythmias	0.000	0.992	0.008
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.008	0.992	0.000
M25.4 Effusion of joint	0.008	0.992	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.992	0.008
I30.8 Other forms of acute pericarditis	0.000	0.992	0.007
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.992	0.007
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.008	0.992	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.008	0.992	0.000
I49.1 Atrial premature depolarisation	0.000	0.992	0.007
I95.1 Orthostatic hypotension	0.000	0.992	0.007
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.992	0.008
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.007	0.992	0.000
M20.4 Other hammer toe(s) (acquired)	0.007	0.993	0.000
I42 Cardiomyopathy	0.000	0.993	0.007
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.007	0.993	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.007	0.993	0.000
M65 Synovitis and tenosynovitis	0.007	0.993	0.000
I50.9 Heart failure, unspecified	0.000	0.993	0.007
M20.2 Hallux rigidus	0.007	0.993	0.000
I30.1 Infective pericarditis	0.000	0.993	0.007
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.007	0.993	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.007	0.993	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.007	0.993	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.007	0.993	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.007	0.993	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.993	0.007
R22.0 Localised swelling, mass and lump, head	0.007	0.993	0.000
R07.1 Chest pain on breathing	0.000	0.993	0.006
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.993	0.007
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.993	0.007
I46.9 Cardiac arrest, unspecified	0.000	0.993	0.007
R22.1 Localised swelling, mass and lump, neck	0.007	0.993	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.006	0.993	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.006	0.994	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.994	0.006
I49.3 Ventricular premature depolarisation	0.000	0.994	0.006
I35.0 Aortic (valve) stenosis	0.000	0.994	0.006
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.006	0.994	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.006	0.994	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.994	0.006
I31.8 Other specified diseases of pericardium	0.000	0.994	0.006
I31.2 Haemopericardium, not elsewhere classified	0.000	0.994	0.006
I31.1 Chronic constrictive pericarditis	0.000	0.994	0.006
I31.0 Chronic adhesive pericarditis	0.000	0.994	0.006
M25.40 Effusion of joint (Multiple sites)	0.006	0.994	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.994	0.006
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.006	0.994	0.000
M25.49 Effusion of joint (Site unspecified)	0.006	0.994	0.000
M25.48 Effusion of joint (Other)	0.006	0.994	0.000
M25.44 Effusion of joint (Hand)	0.006	0.994	0.000
M25.43 Effusion of joint (Forearm)	0.006	0.994	0.000
M25.42 Effusion of joint (Upper arm)	0.006	0.994	0.000
M25.41 Effusion of joint (Shoulder region)	0.006	0.994	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.994	0.006
Z95.0 Presence of cardiac pacemaker	0.000	0.994	0.006
M20.5 Other deformities of toe(s) (acquired)	0.006	0.994	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.006	0.994	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.006	0.994	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.006	0.994	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.006	0.994	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.006	0.994	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.006	0.994	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.006	0.994	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.006	0.994	0.000
I49.5 Sick sinus syndrome	0.000	0.994	0.006
I35.1 Aortic (valve) insufficiency	0.000	0.994	0.006
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.994	0.005
I42.6 Alcoholic cardiomyopathy	0.000	0.994	0.005
I42.5 Other restrictive cardiomyopathy	0.000	0.994	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations