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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73313995
log Bayes Factor = 22.0276
Chromosome 12   position 33,622,807  (GRCh37) Explore rs73313995 on Ensembl!
Variant rs73313995 is part of Cluster X0177

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
J45 Asthma
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
J45.9 Asthma, unspecified
0.997 0.003 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.997 0.003 0.000
N30 Cystitis
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
R30-R39 Symptoms and signs involving the urinary system
0.995 0.005 0.000
J44 Other chronic obstructive pulmonary disease
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
R42 Dizziness and giddiness
0.993 0.007 0.000
E70-E90 Metabolic disorders
0.989 0.011 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.983 0.017 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
H25-H28 Disorders of lens
0.979 0.021 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.977 0.023 0.000
Chapter II Neoplasms
0.976 0.024 0.000
B35-B49 Mycoses
0.975 0.025 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.974 0.026 0.000
N30.2 Other chronic cystitis
0.974 0.026 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.969 0.031 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.961 0.039 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.961 0.039 0.000
B37 Candidiasis
0.958 0.042 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.957 0.043 0.000
H00 Hordeolum and chalazion
0.956 0.044 0.000
H30-H36 Disorders of choroid and retina
0.954 0.046 0.000
I60-I69 Cerebrovascular diseases
0.952 0.048 0.000
H25 Senile cataract
0.950 0.050 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.945 0.055 0.000
C15-C26 Malignant neoplasms of digestive organs
0.944 0.056 0.000
R33 Retention of urine
0.941 0.059 0.000
H00.1 Chalazion
0.940 0.060 0.000
N30.9 Cystitis, unspecified
0.936 0.064 0.000
E87.5 Hyperkalaemia
0.935 0.065 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.931 0.069 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.930 0.070 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.927 0.073 0.000
I73 Other peripheral vascular diseases
0.926 0.074 0.000
H25.1 Senile nuclear cataract
0.926 0.074 0.000
R32 Unspecified urinary incontinence
0.925 0.075 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.923 0.077 0.000
R00 Abnormalities of heart beat
0.922 0.078 0.000
B37.8 Candidiasis of other sites
0.920 0.080 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.912 0.088 0.000
S20-S29 Injuries to the thorax
0.911 0.089 0.000
E20-E35 Disorders of other endocrine glands
0.908 0.092 0.000
R04 Haemorrhage from respiratory passages
0.906 0.094 0.000
S50-S59 Injuries to the elbow and forearm
0.898 0.102 0.000
I73.0 Raynaud's syndrome
0.898 0.102 0.000
Chapter XX External causes of morbidity and mortality
0.897 0.103 0.000
J00-J06 Acute upper respiratory infections
0.897 0.103 0.000
N32 Other disorders of bladder
0.896 0.104 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.895 0.105 0.000
I67 Other cerebrovascular diseases
0.892 0.108 0.000
R00.0 Tachycardia, unspecified
0.890 0.110 0.000
N00-N08 Glomerular diseases
0.881 0.119 0.000
I30-I52 Other forms of heart disease
0.880 0.120 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.879 0.121 0.000
G35 Multiple sclerosis
0.879 0.121 0.000
Chapter V Mental and behavioural disorders
0.876 0.124 0.000
J47 Bronchiectasis
0.876 0.124 0.000
C18 Malignant neoplasm of colon
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.874 0.126 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.874 0.126 0.000
H40-H42 Glaucoma
0.874 0.126 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.873 0.127 0.000
N35 Urethral stricture
0.872 0.128 0.000
D00-D09 In situ neoplasms
0.872 0.128 0.000
H33 Retinal detachments and breaks
0.867 0.133 0.000
H25.9 Senile cataract, unspecified
0.863 0.137 0.000
H55-H59 Other disorders of eye and adnexa
0.861 0.139 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.860 0.140 0.000
R35 Polyuria
0.860 0.140 0.000
N25-N29 Other disorders of kidney and ureter
0.859 0.141 0.000
N32.8 Other specified disorders of bladder
0.857 0.143 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.856 0.144 0.000
E00-E07 Disorders of thyroid gland
0.855 0.145 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.850 0.149 0.000
R00.2 Palpitations
0.850 0.150 0.000
R39 Other symptoms and signs involving the urinary system
0.848 0.152 0.000
J90-J94 Other diseases of pleura
0.846 0.154 0.000
B37.0 Candidal stomatitis
0.846 0.154 0.000
C60-C63 Malignant neoplasms of male genital organs
0.842 0.158 0.000
B95-B98 Bacterial, viral and other infectious agents
0.841 0.159 0.000
E78.5 Hyperlipidaemia, unspecified
0.836 0.164 0.000
W00-W19 Falls
0.834 0.166 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.832 0.168 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.830 0.170 0.000
G30-G32 Other degenerative diseases of the nervous system
0.827 0.173 0.000
N30.8 Other cystitis
0.827 0.173 0.000
N60-N64 Disorders of breast
0.824 0.176 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.823 0.177 0.000
H33.2 Serous retinal detachment
0.823 0.177 0.000
R94 Abnormal results of function studies
0.822 0.178 0.000
J46 Status asthmaticus
0.822 0.178 0.000
H53-H54 Visual disturbances and blindness
0.819 0.181 0.000
S90-S99 Injuries to the ankle and foot
0.817 0.183 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.815 0.185 0.000
R04.2 Haemoptysis
0.815 0.185 0.000
G90-G99 Other disorders of the nervous system
0.815 0.185 0.000
J30-J39 Other diseases of upper respiratory tract
0.814 0.186 0.000
I05-I09 Chronic rheumatic heart diseases
0.811 0.189 0.000
S80-S89 Injuries to the knee and lower leg
0.809 0.191 0.000
H36 Retinal disorders in diseases classified elsewhere
0.809 0.191 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.808 0.192 0.000
G20-G26 Extrapyramidal and movement disorders
0.808 0.192 0.000
N10-N16 Renal tubulo-interstitial diseases
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.807 0.193 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
D04 Carcinoma in situ of skin
0.806 0.194 0.000
T66-T78 Other and unspecified effects of external causes
0.805 0.195 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.804 0.196 0.000
R45 Symptoms and signs involving emotional state
0.804 0.196 0.000
I47 Paroxysmal tachycardia
0.802 0.198 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.802 0.198 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.801 0.199 0.000
C18.7 Sigmoid colon
0.801 0.199 0.000
N30.1 Interstitial cystitis (chronic)
0.799 0.200 0.000
R04.0 Epistaxis
0.795 0.205 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.794 0.206 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.794 0.206 0.000
I77 Other disorders of arteries and arterioles
0.794 0.206 0.000
J95-J99 Other diseases of the respiratory system
0.792 0.208 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.790 0.210 0.000
H26 Other cataract
0.789 0.211 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.788 0.212 0.000
I67.9 Cerebrovascular disease, unspecified
0.788 0.212 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.784 0.216 0.000
H35 Other retinal disorders
0.784 0.216 0.000
H40 Glaucoma
0.783 0.217 0.000
S70-S79 Injuries to the hip and thigh
0.783 0.217 0.000
N35.9 Urethral stricture, unspecified
0.782 0.218 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.779 0.221 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.779 0.221 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.779 0.221 0.000
B37.9 Candidiasis, unspecified
0.779 0.221 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.778 0.222 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.778 0.222 0.000
H27 Other disorders of lens
0.777 0.223 0.000
E78.0 Pure hypercholesterolaemia
0.776 0.224 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.775 0.225 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.775 0.225 0.000
R01 Cardiac murmurs and other cardiac sounds
0.775 0.225 0.000
B25-B34 Other viral diseases
0.775 0.225 0.000
N03 Chronic nephritic syndrome
0.773 0.227 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.771 0.229 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.770 0.230 0.000
S51 Open wound of forearm
0.770 0.230 0.000
E89.0 Postprocedural hypothyroidism
0.768 0.232 0.000
N39 Other disorders of urinary system
0.768 0.232 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.765 0.235 0.000
B35 Dermatophytosis
0.765 0.235 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.764 0.236 0.000
I67.8 Other specified cerebrovascular diseases
0.763 0.237 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.763 0.237 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.763 0.237 0.000
E86 Volume depletion
0.762 0.238 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.761 0.239 0.000
E05.9 Thyrotoxicosis, unspecified
0.760 0.240 0.000
J92 Pleural plaque
0.760 0.240 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.759 0.241 0.000
N20-N23 Urolithiasis
0.758 0.242 0.000
C64-C68 Malignant neoplasms of urinary tract
0.757 0.243 0.000
E50-E64 Other nutritional deficiencies
0.757 0.243 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.756 0.244 0.000
Q60-Q64 Congenital malformations of the urinary system
0.754 0.246 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.753 0.247 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.752 0.248 0.000
R39.1 Other difficulties with micturition
0.752 0.248 0.000
E87.0 Hyperosmolality and hypernatraemia
0.751 0.249 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.751 0.249 0.000
C17 Malignant neoplasm of small intestine
0.750 0.250 0.000
I71 Aortic aneurysm and dissection
0.750 0.250 0.000
W19 Unspecified fall
0.749 0.251 0.000
I10-I15 Hypertensive diseases
0.749 0.251 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
R02 Gangrene, not elsewhere classified
0.748 0.252 0.000
J43 Emphysema
0.748 0.252 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.747 0.253 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.746 0.253 0.000
I47.1 Supraventricular tachycardia
0.744 0.256 0.000
G70-G73 Diseases of myoneural junction and muscle
0.742 0.258 0.000
A30-A49 Other bacterial diseases
0.741 0.259 0.000
J00 Acute nasopharyngitis [common cold]
0.740 0.260 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.738 0.262 0.000
S27 Injury of other and unspecified intrathoracic organs
0.737 0.262 0.000
F30-F39 Mood [affective] disorders
0.737 0.263 0.000
I31 Other diseases of pericardium
0.737 0.263 0.000
C21 Malignant neoplasm of anus and anal canal
0.737 0.263 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.736 0.264 0.000
I70 Atherosclerosis
0.734 0.266 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.734 0.266 0.000
H10-H13 Disorders of conjunctiva
0.732 0.268 0.000
S50 Superficial injury of forearm
0.731 0.269 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.730 0.270 0.000
C61 Malignant neoplasm of prostate
0.730 0.270 0.000
I49 Other cardiac arrhythmias
0.729 0.271 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.728 0.271 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.728 0.271 0.000
I74 Arterial embolism and thrombosis
0.728 0.272 0.000
T43.2 Other and unspecified antidepressants
0.728 0.272 0.000
J93 Pneumothorax
0.728 0.272 0.000
J36 Peritonsillar abscess
0.727 0.273 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.726 0.274 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.726 0.274 0.000
C16 Malignant neoplasm of stomach
0.724 0.275 0.000
A80-A89 Viral infections of the central nervous system
0.724 0.276 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.722 0.278 0.000
N99-N99 Other disorders of the genitourinary system
0.722 0.278 0.000
N30.3 Trigonitis
0.721 0.279 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.719 0.281 0.000
H57 Other disorders of eye and adnexa
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
N39.3 Stress incontinence
0.716 0.284 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
J45.8 Mixed asthma
0.716 0.284 0.000
J45.1 Nonallergic asthma
0.716 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
R46 Symptoms and signs involving appearance and behaviour
0.715 0.285 0.000
R43 Disturbances of smell and taste
0.715 0.285 0.000
C15 Malignant neoplasm of oesophagus
0.715 0.285 0.000
N30.4 Irradiation cystitis
0.714 0.286 0.000
N30.0 Acute cystitis
0.714 0.286 0.000
N32.9 Bladder disorder, unspecified
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
R36 Urethral discharge
0.713 0.286 0.000
R34 Anuria and oliguria
0.713 0.286 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
E78.8 Other disorders of lipoprotein metabolism
0.712 0.288 0.000
I78 Diseases of capillaries
0.711 0.289 0.000
R31 Unspecified haematuria
0.711 0.289 0.000
J45.0 Predominantly allergic asthma
0.711 0.289 0.000
N36 Other disorders of urethra
0.710 0.290 0.000
E21.0 Primary hyperparathyroidism
0.710 0.290 0.000
C20 Malignant neoplasm of rectum
0.709 0.291 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
R30 Pain associated with micturition
0.709 0.291 0.000
S20 Superficial injury of thorax
0.709 0.291 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.708 0.292 0.000
I60 Subarachnoid haemorrhage
0.707 0.292 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.707 0.293 0.000
E65-E68 Obesity and other hyperalimentation
0.707 0.293 0.000
E29 Testicular dysfunction
0.707 0.293 0.000
H36.0 Diabetic retinopathy
0.705 0.295 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.704 0.295 0.000
T87 Complications peculiar to reattachment and amputation
0.704 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.704 0.296 0.000
J04 Acute laryngitis and tracheitis
0.703 0.297 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.702 0.298 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.700 0.300 0.000
I33 Acute and subacute endocarditis
0.700 0.300 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.700 0.300 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.700 0.300 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.700 0.300 0.000
H43-H45 Disorders of vitreous body and globe
0.700 0.300 0.000
B48 Other mycoses, not elsewhere classified
0.699 0.301 0.000
B47 Mycetoma
0.699 0.301 0.000
B46 Zygomycosis
0.699 0.301 0.000
B45 Cryptococcosis
0.699 0.301 0.000
B44 Aspergillosis
0.699 0.301 0.000
B43 Chromomycosis and phaeomycotic abscess
0.699 0.301 0.000
B42 Sporotrichosis
0.699 0.301 0.000
B41 Paracoccidioidomycosis
0.699 0.301 0.000
B40 Blastomycosis
0.699 0.301 0.000
B39 Histoplasmosis
0.699 0.301 0.000
B38 Coccidioidomycosis
0.699 0.301 0.000
B36 Other superficial mycoses
0.699 0.301 0.000
B49 Unspecified mycosis
0.699 0.301 0.000
E28 Ovarian dysfunction
0.699 0.301 0.000
I72 Other aneurysm
0.699 0.301 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.698 0.302 0.000
J60-J70 Lung diseases due to external agents
0.697 0.303 0.000
J40 Bronchitis, not specified as acute or chronic
0.696 0.304 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.696 0.304 0.000
N03.9 Unspecified
0.696 0.304 0.000
H05 Disorders of orbit
0.695 0.305 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.695 0.305 0.000
J92.9 Pleural plaque without asbestos
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.306 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.692 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.692 0.308 0.000
H40.1 Primary open-angle glaucoma
0.692 0.308 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.691 0.309 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.689 0.311 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.689 0.311 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.689 0.311 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.688 0.312 0.000
H35.0 Background retinopathy and retinal vascular changes
0.687 0.313 0.000
B37.7 Candidal septicaemia
0.687 0.313 0.000
B37.6 Candidal endocarditis
0.687 0.313 0.000
B37.5 Candidal meningitis
0.687 0.313 0.000
B37.4 Candidiasis of other urogenital sites
0.687 0.313 0.000
B37.2 Candidiasis of skin and nail
0.687 0.313 0.000
B37.1 Pulmonary candidiasis
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.686 0.314 0.000
E87.4 Mixed disorder of acid-base balance
0.686 0.314 0.000
E87.3 Alkalosis
0.686 0.314 0.000
J35 Chronic diseases of tonsils and adenoids
0.686 0.314 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.684 0.315 0.000
I42 Cardiomyopathy
0.684 0.316 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.684 0.316 0.000
H31 Other disorders of choroid
0.684 0.316 0.000
H30 Chorioretinal inflammation
0.684 0.316 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.684 0.316 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.684 0.316 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.684 0.316 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.683 0.317 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.683 0.317 0.000
E22 Hyperfunction of pituitary gland
0.683 0.317 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.683 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.683 0.317 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.682 0.317 0.000
S22.3 Fracture of rib
0.682 0.318 0.000
H25.2 Senile cataract, morgagnian type
0.681 0.319 0.000
E06 Thyroiditis
0.681 0.319 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.679 0.321 0.000
R09.1 Pleurisy
0.679 0.321 0.000
S52 Fracture of forearm
0.678 0.322 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.678 0.322 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
N05 Unspecified nephritic syndrome
0.677 0.323 0.000
D04.5 Skin of trunk
0.677 0.323 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.677 0.323 0.000
C18.5 Splenic flexure
0.677 0.323 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.677 0.323 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.677 0.323 0.000
C23 Malignant neoplasm of gallbladder
0.677 0.323 0.000
R41.0 Disorientation, unspecified
0.677 0.323 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.676 0.323 0.000
C18.3 Hepatic flexure
0.676 0.324 0.000
H35.8 Other specified retinal disorders
0.676 0.324 0.000
R94.5 Abnormal results of liver function studies
0.676 0.324 0.000
H01 Other inflammation of eyelid
0.675 0.325 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.675 0.325 0.000
C67 Malignant neoplasm of bladder
0.675 0.325 0.000
C18.2 Ascending colon
0.674 0.326 0.000
N17-N19 Renal failure
0.674 0.326 0.000
D04.2 Skin of ear and external auricular canal
0.673 0.327 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.673 0.327 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.672 0.328 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.671 0.329 0.000
A00-A09 Intestinal infectious diseases
0.671 0.329 0.000
H46 Optic neuritis
0.671 0.329 0.000
I67.2 Cerebral atherosclerosis
0.670 0.330 0.000
G20 Parkinson's disease
0.670 0.330 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.670 0.330 0.000
C51-C58 Malignant neoplasms of female genital organs
0.669 0.331 0.000
J42 Unspecified chronic bronchitis
0.669 0.331 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.669 0.331 0.000
E78.6 Lipoprotein deficiency
0.667 0.333 0.000
E78.4 Other hyperlipidaemia
0.667 0.333 0.000
E78.3 Hyperchylomicronaemia
0.667 0.333 0.000
E78.2 Mixed hyperlipidaemia
0.667 0.333 0.000
E78.1 Pure hyperglyceridaemia
0.667 0.333 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.667 0.333 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.667 0.333 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.666 0.334 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.666 0.334 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.666 0.334 0.000
T78 Adverse effects, not elsewhere classified
0.665 0.335 0.000
F41 Other anxiety disorders
0.664 0.335 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.664 0.336 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.664 0.336 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.664 0.336 0.000
T83.2 Mechanical complication of graft of urinary organ
0.664 0.336 0.000
I73.8 Other specified peripheral vascular diseases
0.664 0.336 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.664 0.336 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.664 0.336 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.664 0.336 0.000
J03 Acute tonsillitis
0.664 0.336 0.000
I67.1 Cerebral aneurysm, nonruptured
0.662 0.338 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.662 0.338 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.662 0.338 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.662 0.338 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.662 0.338 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.662 0.338 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
T36 Poisoning by systemic antibiotics
0.662 0.338 0.000
D09 Carcinoma in situ of other and unspecified sites
0.662 0.338 0.000
W13 Fall from, out of or through building or structure
0.661 0.339 0.000
E88 Other metabolic disorders
0.661 0.339 0.000
H40.9 Glaucoma, unspecified
0.661 0.339 0.000
J37 Chronic laryngitis and laryngotracheitis
0.661 0.339 0.000
H53 Visual disturbances
0.660 0.340 0.000
G37 Other demyelinating diseases of central nervous system
0.660 0.340 0.000
R45.2 Unhappiness
0.659 0.341 0.000
H34 Retinal vascular occlusions
0.658 0.341 0.000
C77.2 Intra-abdominal lymph nodes
0.657 0.343 0.000
N62 Hypertrophy of breast
0.657 0.343 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.657 0.343 0.000
R47-R49 Symptoms and signs involving speech and voice
0.656 0.344 0.000
D06 Carcinoma in situ of cervix uteri
0.656 0.344 0.000
D03 Melanoma in situ
0.656 0.344 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.655 0.345 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.654 0.346 0.000
G36 Other acute disseminated demyelination
0.654 0.346 0.000
E10-E14 Diabetes mellitus
0.654 0.346 0.000
I05 Rheumatic mitral valve diseases
0.653 0.346 0.000
S29 Other and unspecified injuries of thorax
0.653 0.347 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.653 0.347 0.000
S26 Injury of heart
0.653 0.347 0.000
S25 Injury of blood vessels of thorax
0.653 0.347 0.000
S24 Injury of nerves and spinal cord at thorax level
0.653 0.347 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.653 0.347 0.000
S21 Open wound of thorax
0.653 0.347 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.652 0.348 0.000
C18.0 Caecum
0.652 0.348 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.651 0.348 0.000
Chapter VIII Diseases of the ear and mastoid process
0.651 0.349 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.651 0.349 0.000
E34 Other endocrine disorders
0.651 0.349 0.000
E32 Diseases of thymus
0.651 0.349 0.000
E31 Polyglandular dysfunction
0.651 0.349 0.000
E30 Disorders of puberty, not elsewhere classified
0.651 0.349 0.000
E26 Hyperaldosteronism
0.651 0.349 0.000
E25 Adrenogenital disorders
0.651 0.349 0.000
E24 Cushing's syndrome
0.651 0.349 0.000
E23 Hypofunction and other disorders of pituitary gland
0.651 0.349 0.000
E20 Hypoparathyroidism
0.651 0.349 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.650 0.350 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.650 0.350 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.650 0.350 0.000
R04.1 Haemorrhage from throat
0.650 0.350 0.000
H26.4 After-cataract
0.650 0.350 0.000
C80 Malignant neoplasm without specification of site
0.647 0.353 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.647 0.353 0.000
C79 Secondary malignant neoplasm of other sites
0.647 0.353 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.646 0.354 0.000
R09.2 Respiratory arrest
0.646 0.354 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.646 0.354 0.000
I12 Hypertensive renal disease
0.646 0.354 0.000
S80 Superficial injury of lower leg
0.646 0.354 0.000
E27 Other disorders of adrenal gland
0.645 0.354 0.000
S89 Other and unspecified injuries of lower leg
0.645 0.355 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.645 0.355 0.000
T90 Sequelae of injuries of head
0.645 0.355 0.000
I77.6 Arteritis, unspecified
0.645 0.355 0.000
I45 Other conduction disorders
0.645 0.355 0.000
I30 Acute pericarditis
0.644 0.356 0.000
F32 Depressive episode
0.644 0.356 0.000
W20-W49 Exposure to inanimate mechanical forces
0.644 0.356 0.000
S59 Other and unspecified injuries of forearm
0.644 0.356 0.000
S58 Traumatic amputation of forearm
0.644 0.356 0.000
S57 Crushing injury of forearm
0.644 0.356 0.000
S56 Injury of muscle and tendon at forearm level
0.644 0.356 0.000
S55 Injury of blood vessels at forearm level
0.644 0.356 0.000
S54 Injury of nerves at forearm level
0.644 0.356 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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