TreeWAS – Variant ID: rs7341475

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.3 With ophthalmic complications	0.986	0.014	0.000
E11 Non-insulin-dependent diabetes mellitus	0.978	0.022	0.000
E11.9 Without complications	0.974	0.026	0.000
E11.8 With unspecified complications	0.760	0.239	0.000
E11.4 With neurological complications	0.752	0.248	0.000
E11.2 With renal complications	0.745	0.255	0.000
E11.7 With multiple complications	0.701	0.299	0.000
E10-E14 Diabetes mellitus	0.697	0.303	0.000
E11.6 With other specified complications	0.679	0.321	0.000
E11.1 With ketoacidosis	0.657	0.343	0.000
E10 Insulin-dependent diabetes mellitus	0.644	0.356	0.000
E10.8 With unspecified complications	0.609	0.391	0.000
E11.0 With coma	0.563	0.436	0.000
E10.0 With coma	0.553	0.447	0.000
E11.5 With peripheral circulatory complications	0.540	0.460	0.000
E10.3 With ophthalmic complications	0.534	0.466	0.000
E13 Other specified diabetes mellitus	0.525	0.475	0.000
E10.7 With multiple complications	0.520	0.480	0.000
E12 Malnutrition-related diabetes mellitus	0.500	0.500	0.000
E10.2 With renal complications	0.473	0.527	0.000
E10.1 With ketoacidosis	0.472	0.528	0.000
E14 Unspecified diabetes mellitus	0.449	0.551	0.000
E10.5 With peripheral circulatory complications	0.435	0.565	0.000
E13.3 With ophthalmic complications	0.405	0.595	0.000
E10.6 With other specified complications	0.397	0.603	0.000
E13.8 With unspecified complications	0.376	0.623	0.000
E13.7 With multiple complications	0.376	0.623	0.000
E13.6 With other specified complications	0.376	0.623	0.000
E13.5 With peripheral circulatory complications	0.376	0.623	0.000
E13.4 With neurological complications	0.376	0.623	0.000
E13.2 With renal complications	0.376	0.623	0.000
E13.1 With ketoacidosis	0.376	0.623	0.000
E13.0 With coma	0.376	0.623	0.000
E10.4 With neurological complications	0.375	0.625	0.000
E13.9 Without complications	0.373	0.627	0.000
E14.4 With neurological complications	0.362	0.638	0.000
E12.9 Without complications	0.358	0.641	0.000
E12.8 With unspecified complications	0.358	0.641	0.000
E12.7 With multiple complications	0.358	0.641	0.000
E12.6 With other specified complications	0.358	0.641	0.000
E12.5 With peripheral circulatory complications	0.358	0.641	0.000
E12.4 With neurological complications	0.358	0.641	0.000
E12.3 With ophthalmic complications	0.358	0.641	0.000
E12.2 With renal complications	0.358	0.641	0.000
E12.1 With ketoacidosis	0.358	0.641	0.000
E12.0 With coma	0.358	0.641	0.000
E14.1 With ketoacidosis	0.358	0.642	0.000
E14.8 With unspecified complications	0.330	0.670	0.000
E14.7 With multiple complications	0.322	0.678	0.000
E14.6 With other specified complications	0.322	0.678	0.000
E14.5 With peripheral circulatory complications	0.322	0.678	0.000
E14.2 Withrenal complications	0.322	0.678	0.000
E14.0 With coma	0.322	0.678	0.000
E14.3 With ophthalmic complications	0.300	0.700	0.000
E10.9 Without complications	0.185	0.815	0.000
E14.9 Without complications	0.118	0.882	0.000
H36.0 Diabetic retinopathy	0.063	0.937	0.000
H36 Retinal disorders in diseases classified elsewhere	0.030	0.970	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.977	0.023
H36.8 Other retinal disorders in diseases classified elsewhere	0.022	0.978	0.000
N60 Benign mammary dysplasia	0.000	0.982	0.018
E87.5 Hyperkalaemia	0.000	0.983	0.017
N60.3 Fibrosclerosis of breast	0.000	0.983	0.017
Chapter IV Endocrine, nutritional and metabolic diseases	0.016	0.984	0.000
N60.0 Solitary cyst of breast	0.000	0.984	0.016
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.015	0.985	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.014	0.986	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.986	0.014
N60.2 Fibroadenosis of breast	0.000	0.986	0.014
Q27 Other congenital malformations of peripheral vascular system	0.013	0.987	0.000
Q23 Congenital malformations of aortic and mitral valves	0.013	0.987	0.000
E65-E68 Obesity and other hyperalimentation	0.012	0.988	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.012	0.988	0.000
Q28 Other congenital malformations of circulatory system	0.012	0.988	0.000
Q21 Congenital malformations of cardiac septa	0.012	0.988	0.000
E20-E35 Disorders of other endocrine glands	0.012	0.988	0.000
Q23.1 Congenital insufficiency of aortic valve	0.012	0.988	0.000
Q25 Congenital malformations of great arteries	0.012	0.988	0.000
E27 Other disorders of adrenal gland	0.012	0.988	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.011	0.989	0.000
Q24 Other congenital malformations of heart	0.011	0.989	0.000
E34 Other endocrine disorders	0.011	0.989	0.000
Q21.1 Atrial septal defect	0.011	0.989	0.000
E50-E64 Other nutritional deficiencies	0.010	0.990	0.000
E26 Hyperaldosteronism	0.010	0.990	0.000
Q26 Congenital malformations of great veins	0.010	0.990	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.010	0.990	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.010	0.990	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.010	0.990	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.990	0.010
Q28.3 Other malformations of cerebral vessels	0.010	0.990	0.000
E34.9 Endocrine disorder, unspecified	0.010	0.990	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.010	0.990	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.010	0.990	0.000
N60.8 Other benign mammary dysplasias	0.000	0.990	0.010
Q25.1 Coarctation of aorta	0.010	0.990	0.000
E66 Obesity	0.010	0.990	0.000
Q21.0 Ventricular septal defect	0.010	0.990	0.000
Q23.0 Congenital stenosis of aortic valve	0.009	0.990	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.009	0.990	0.000
Q27.4 Congenital phlebectasia	0.009	0.990	0.000
Q27.2 Other congenital malformations of renal artery	0.009	0.990	0.000
Q27.1 Congenital renal artery stenosis	0.009	0.990	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.009	0.990	0.000
E40-E46 Malnutrition	0.009	0.991	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.009	0.991	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.009	0.991	0.000
Q23.4 Hypoplastic left heart syndrome	0.009	0.991	0.000
Q23.3 Congenital mitral insufficiency	0.009	0.991	0.000
Q23.2 Congenital mitral stenosis	0.009	0.991	0.000
E27.9 Disorder of adrenal gland, unspecified	0.009	0.991	0.000
Q27.3 Peripheral arteriovenous malformation	0.009	0.991	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.009	0.991	0.000
E27.8 Other specified disorders of adrenal gland	0.009	0.991	0.000
E24 Cushing's syndrome	0.009	0.991	0.000
E25 Adrenogenital disorders	0.009	0.991	0.000
E67 Other hyperalimentation	0.009	0.991	0.000
E68 Sequelae of hyperalimentation	0.009	0.991	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.009	0.991	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.009	0.991	0.000
Q28.1 Other malformations of precerebral vessels	0.009	0.991	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.009	0.991	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.009	0.991	0.000
Q21.8 Other congenital malformations of cardiac septa	0.009	0.991	0.000
Q21.4 Aortopulmonary septal defect	0.009	0.991	0.000
Q21.3 Tetralogy of Fallot	0.009	0.991	0.000
Q21.2 Atrioventricular septal defect	0.009	0.991	0.000
E61 Deficiency of other nutrient elements	0.009	0.991	0.000
Q25.6 Stenosis of pulmonary artery	0.009	0.991	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.009	0.991	0.000
E32 Diseases of thymus	0.009	0.991	0.000
E31 Polyglandular dysfunction	0.009	0.991	0.000
E30 Disorders of puberty, not elsewhere classified	0.009	0.991	0.000
E65 Localised adiposity	0.009	0.991	0.000
Q50-Q56 Congenital malformations of genital organs	0.009	0.991	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
Q00-Q07 Congenital malformations of the nervous system	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.008	0.991	0.000
Q25.8 Other congenital malformations of great arteries	0.008	0.991	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.008	0.991	0.000
Q25.5 Atresia of pulmonary artery	0.008	0.991	0.000
Q25.4 Other congenital malformations of aorta	0.008	0.991	0.000
Q25.3 Stenosis of aorta	0.008	0.991	0.000
Q25.2 Atresia of aorta	0.008	0.991	0.000
Q25.0 Patent ductus arteriosus	0.008	0.991	0.000
E27.5 Adrenomedullary hyperfunction	0.008	0.991	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.008	0.991	0.000
E27.0 Other adrenocortical overactivity	0.008	0.991	0.000
E26.0 Primary hyperaldosteronism	0.008	0.991	0.000
E27.2 Addisonian crisis	0.008	0.991	0.000
Q24.8 Other specified congenital malformations of heart	0.008	0.991	0.000
E26.9 Hyperaldosteronism, unspecified	0.008	0.991	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
Q24.6 Congenital heart block	0.008	0.992	0.000
Q24.4 Congenital subaortic stenosis	0.008	0.992	0.000
Q24.3 Pulmonary infundibular stenosis	0.008	0.992	0.000
Q24.2 Cor triatriatum	0.008	0.992	0.000
Q24.1 Levocardia	0.008	0.992	0.000
Q24.0 Dextrocardia	0.008	0.992	0.000
E51 Thiamine deficiency	0.008	0.992	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.008	0.992	0.000
E61.1 Iron deficiency	0.008	0.992	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.008	0.992	0.000
E20 Hypoparathyroidism	0.008	0.992	0.000
E34.5 Androgen resistance syndrome	0.008	0.992	0.000
E34.4 Constitutional tall stature	0.008	0.992	0.000
E34.3 Short stature, not elsewhere classified	0.008	0.992	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.008	0.992	0.000
E34.1 Other hypersecretion of intestinal hormones	0.008	0.992	0.000
Q39 Congenital malformations of oesophagus	0.008	0.992	0.000
E34.0 Carcinoid syndrome	0.008	0.992	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.008	0.992	0.000
E63 Other nutritional deficiencies	0.008	0.992	0.000
E56 Other vitamin deficiencies	0.008	0.992	0.000
E50 Vitamin A deficiency	0.008	0.992	0.000
E60 Dietary zinc deficiency	0.008	0.992	0.000
E59 Dietary selenium deficiency	0.008	0.992	0.000
E58 Dietary calcium deficiency	0.008	0.992	0.000
E54 Ascorbic acid deficiency	0.008	0.992	0.000
E52 Niacin deficiency [pellagra]	0.008	0.992	0.000
E26.8 Other hyperaldosteronism	0.008	0.992	0.000
E26.1 Secondary hyperaldosteronism	0.008	0.992	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.007	0.992	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.007	0.992	0.000
Q20.6 Isomerism of atrial appendages	0.007	0.992	0.000
Q20.5 Discordant atrioventricular connexion	0.007	0.992	0.000
Q20.4 Double inlet ventricle	0.007	0.992	0.000
Q20.3 Discordant ventriculoarterial connexion	0.007	0.992	0.000
Q20.2 Double outlet left ventricle	0.007	0.992	0.000
Q20.1 Double outlet right ventricle	0.007	0.992	0.000
Q20.0 Common arterial trunk	0.007	0.992	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.007	0.992	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.007	0.992	0.000
Q22.6 Hypoplastic right heart syndrome	0.007	0.992	0.000
Q22.5 Ebstein's anomaly	0.007	0.992	0.000
Q22.4 Congenital tricuspid stenosis	0.007	0.992	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.007	0.992	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.007	0.992	0.000
Q22.1 Congenital pulmonary valve stenosis	0.007	0.992	0.000
Q22.0 Pulmonary valve atresia	0.007	0.992	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.007	0.992	0.000
Q26.8 Other congenital malformations of great veins	0.007	0.992	0.000
Q26.6 Portal vein-hepatic artery fistula	0.007	0.992	0.000
Q26.5 Anomalous portal venous connexion	0.007	0.992	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.007	0.992	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.007	0.992	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.007	0.992	0.000
Q26.1 Persistent left superior vena cava	0.007	0.992	0.000
Q26.0 Congenital stenosis of vena cava	0.007	0.992	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.008	0.992	0.000
Q24.5 Malformation of coronary vessels	0.007	0.992	0.000
E27.1 Primary adrenocortical insufficiency	0.008	0.992	0.000
E23.6 Other disorders of pituitary gland	0.007	0.992	0.000
Q39.4 Oesophageal web	0.007	0.992	0.000
N63 Unspecified lump in breast	0.000	0.992	0.008
E34.8 Other specified endocrine disorders	0.007	0.993	0.000
Q54 Hypospadias	0.007	0.993	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.007	0.993	0.000
N60.4 Mammary duct ectasia	0.000	0.993	0.007
E15 Nondiabetic hypoglycaemic coma	0.007	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
Q35-Q37 Cleft lip and cleft palate	0.007	0.993	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.007	0.993	0.000
E66.1 Drug-induced obesity	0.007	0.993	0.000
E29 Testicular dysfunction	0.007	0.993	0.000
Q07 Other congenital malformations of nervous system	0.007	0.993	0.000
E66.8 Other obesity	0.007	0.993	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.007	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
Q05 Spina bifida	0.007	0.993	0.000
Q55 Other congenital malformations of male genital organs	0.007	0.993	0.000
Q52 Other congenital malformations of female genitalia	0.007	0.993	0.000
Q04 Other congenital malformations of brain	0.007	0.993	0.000
Q45 Other congenital malformations of digestive system	0.007	0.993	0.000
Q51 Congenital malformations of uterus and cervix	0.007	0.993	0.000
E24.8 Other Cushing's syndrome	0.007	0.993	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.007	0.993	0.000
E24.3 Ectopic ACTH syndrome	0.007	0.993	0.000
E24.2 Drug-induced Cushing's syndrome	0.007	0.993	0.000
E24.1 Nelson's syndrome	0.007	0.993	0.000
Q53 Undescended testicle	0.007	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.007	0.993	0.000
E25.8 Other adrenogenital disorders	0.007	0.993	0.000
E67.8 Other specified hyperalimentation	0.007	0.993	0.000
E67.3 Hypervitaminosis D	0.007	0.993	0.000
E67.2 Megavitamin-B6 syndrome	0.007	0.993	0.000
E67.1 Hypercarotenaemia	0.007	0.993	0.000
E67.0 Hypervitaminosis A	0.007	0.993	0.000
Q66 Congenital deformities of feet	0.007	0.993	0.000
Q76 Congenital malformations of spine and bony thorax	0.007	0.993	0.000
Q40 Other congenital malformations of upper alimentary tract	0.007	0.993	0.000
E66.0 Obesity due to excess calories	0.007	0.993	0.000
E61.9 Deficiency of nutrient element, unspecified	0.007	0.993	0.000
E61.8 Deficiency of other specified nutrient elements	0.007	0.993	0.000
E61.7 Deficiency of multiple nutrient elements	0.007	0.993	0.000
E61.6 Vanadium deficiency	0.007	0.993	0.000
E61.5 Molybdenum deficiency	0.007	0.993	0.000
E61.4 Chromium deficiency	0.007	0.993	0.000
E61.3 Manganese deficiency	0.007	0.993	0.000
E61.2 Magnesium deficiency	0.007	0.993	0.000
E61.0 Copper deficiency	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
Q80-Q89 Other congenital malformations	0.007	0.993	0.000
E30.9 Disorder of puberty, unspecified	0.006	0.993	0.000
E30.8 Other disorders of puberty	0.006	0.993	0.000
E30.1 Precocious puberty	0.006	0.993	0.000
E30.0 Delayed puberty	0.006	0.993	0.000
E31.9 Polyglandular dysfunction, unspecified	0.006	0.993	0.000
E31.8 Other polyglandular dysfunction	0.006	0.993	0.000
E31.1 Polyglandular hyperfunction	0.006	0.993	0.000
E31.0 Autoimmune polyglandular failure	0.006	0.993	0.000
E32.9 Disease of thymus, unspecified	0.006	0.993	0.000
E32.8 Other diseases of thymus	0.006	0.993	0.000
E32.1 Abscess of thymus	0.006	0.993	0.000
E32.0 Persistent hyperplasia of thymus	0.006	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.006	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.006	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.006	0.993	0.000
Q96 Turner's syndrome	0.007	0.993	0.000
R94.4 Abnormal results of kidney function studies	0.007	0.993	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.006	0.993	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.993	0.000
E22.8 Other hyperfunction of pituitary gland	0.006	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.006	0.993	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.993	0.000
M00.9 Pyogenic arthritis, unspecified	0.006	0.993	0.000
Q06 Other congenital malformations of spinal cord	0.006	0.993	0.000
Q03 Congenital hydrocephalus	0.006	0.993	0.000
Q01 Encephalocele	0.006	0.993	0.000
Q00 Anencephaly and similar malformations	0.006	0.993	0.000
Q02 Microcephaly	0.006	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.993	0.000
E51.2 Wernicke's encephalopathy	0.006	0.994	0.000
Q54.0 Hypospadias, balanic	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
E22.1 Hyperprolactinaemia	0.006	0.994	0.000
E23.2 Diabetes insipidus	0.006	0.994	0.000
Q43 Other congenital malformations of intestine	0.006	0.994	0.000
H30-H36 Disorders of choroid and retina	0.006	0.994	0.000
Q74 Other congenital malformations of limb(s)	0.006	0.994	0.000
N60-N64 Disorders of breast	0.000	0.994	0.006
Q39.6 Diverticulum of oesophagus	0.006	0.994	0.000
E51.9 Thiamine deficiency, unspecified	0.006	0.994	0.000
E51.8 Other manifestations of thiamine deficiency	0.006	0.994	0.000
E51.1 Beriberi	0.006	0.994	0.000
Q07.0 Arnold-Chiari syndrome	0.006	0.994	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.006	0.994	0.000
Q75 Other congenital malformations of skull and face bones	0.006	0.994	0.000
Q73 Reduction defects of unspecified limb	0.006	0.994	0.000
Q72 Reduction defects of lower limb	0.006	0.994	0.000
Q71 Reduction defects of upper limb	0.006	0.994	0.000
Q70 Syndactyly	0.006	0.994	0.000
Q69 Polydactyly	0.006	0.994	0.000
Q68 Other congenital musculoskeletal deformities	0.006	0.994	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.994	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.994	0.006
Q99 Other chromosome abnormalities, not elsewhere classified	0.006	0.994	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.006	0.994	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.006	0.994	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.006	0.994	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.006	0.994	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.006	0.994	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.006	0.994	0.000
Q90 Down's syndrome	0.006	0.994	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
Q78 Other osteochondrodysplasias	0.006	0.994	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.006	0.994	0.000
Q39.8 Other congenital malformations of oesophagus	0.006	0.994	0.000
Q39.5 Congenital dilatation of oesophagus	0.006	0.994	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.006	0.994	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.006	0.994	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.006	0.994	0.000
Q39.0 Atresia of oesophagus without fistula	0.006	0.994	0.000
E28 Ovarian dysfunction	0.005	0.994	0.000
Q05.9 Spina bifida, unspecified	0.006	0.994	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.006	0.994	0.000
Q45.8 Other specified congenital malformations of digestive system	0.006	0.994	0.000
E50.9 Vitamin A deficiency, unspecified	0.006	0.994	0.000
E50.8 Other manifestations of vitamin A deficiency	0.006	0.994	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.006	0.994	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.006	0.994	0.000
E50.5 Vitamin A deficiency with night blindness	0.006	0.994	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.006	0.994	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.006	0.994	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.006	0.994	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.006	0.994	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.006	0.994	0.000
E56.9 Vitamin deficiency, unspecified	0.006	0.994	0.000
E56.8 Deficiency of other vitamins	0.006	0.994	0.000
E56.1 Deficiency of vitamin K	0.006	0.994	0.000
E56.0 Deficiency of vitamin E	0.006	0.994	0.000
E63.9 Nutritional deficiency, unspecified	0.006	0.994	0.000
E63.8 Other specified nutritional deficiencies	0.006	0.994	0.000
E63.1 Imbalance of constituents of food intake	0.006	0.994	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.006	0.994	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.006	0.994	0.000
E64.8 Sequelae of other nutritional deficiencies	0.006	0.994	0.000
E64.3 Sequelae of rickets	0.006	0.994	0.000
E64.2 Sequelae of vitamin C deficiency	0.006	0.994	0.000
E64.1 Sequelae of vitamin A deficiency	0.006	0.994	0.000
E64.0 Sequelae of protein-energy malnutrition	0.006	0.994	0.000
Q66.8 Other congenital deformities of feet	0.006	0.994	0.000
Q65 Congenital deformities of hip	0.006	0.994	0.000
Q96.9 Turner's syndrome, unspecified	0.006	0.994	0.000
Q54.9 Hypospadias, unspecified	0.006	0.994	0.000
Q55.6 Other congenital malformations of penis	0.006	0.994	0.000
R25.2 Cramp and spasm	0.006	0.994	0.000
Q04.6 Congenital cerebral cysts	0.006	0.994	0.000
Q76.0 Spina bifida occulta	0.006	0.994	0.000
Q52.1 Doubling of vagina	0.005	0.994	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.006	0.994	0.000
Q51.3 Bicornate uterus	0.006	0.994	0.000
Q40.2 Other specified congenital malformations of stomach	0.005	0.994	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
Q54.8 Other hypospadias	0.005	0.994	0.000
Q54.4 Congenital chordee	0.005	0.994	0.000
Q54.3 Hypospadias, perineal	0.005	0.994	0.000
Q54.2 Hypospadias, penoscrotal	0.005	0.994	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.994	0.006
E55 Vitamin D deficiency	0.005	0.994	0.000
Q54.1 Hypospadias, penile	0.005	0.994	0.000
Q34 Other congenital malformations of respiratory system	0.005	0.994	0.000
Q33 Congenital malformations of lung	0.005	0.994	0.000
Q32 Congenital malformations of trachea and bronchus	0.005	0.994	0.000
Q31 Congenital malformations of larynx	0.005	0.994	0.000
Q30 Congenital malformations of nose	0.005	0.994	0.000
Q37 Cleft palate with cleft lip	0.005	0.994	0.000
Q36 Cleft lip	0.005	0.994	0.000
Q35 Cleft palate	0.005	0.994	0.000
E53 Deficiency of other B group vitamins	0.005	0.994	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.005	0.994	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.994	0.006
H35 Other retinal disorders	0.005	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.005	0.995	0.000
Q53.1 Undescended testicle, unilateral	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.005	0.995	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.005	0.995	0.000
Q07.8 Other specified congenital malformations of nervous system	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
H35.8 Other specified retinal disorders	0.005	0.995	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.005	0.995	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.005	0.995	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.005	0.995	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.005	0.995	0.000
Q55.5 Congenital absence and aplasia of penis	0.005	0.995	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.005	0.995	0.000
Q55.3 Atresia of vas deferens	0.005	0.995	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.005	0.995	0.000
Q55.1 Hypoplasia of testis and scrotum	0.005	0.995	0.000
Q55.0 Absence and aplasia of testis	0.005	0.995	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.005	0.995	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.005	0.995	0.000
Q52.7 Other congenital malformations of vulva	0.005	0.995	0.000
Q52.6 Congenital malformation of clitoris	0.005	0.995	0.000
Q52.5 Fusion of labia	0.005	0.995	0.000
Q52.4 Other congenital malformations of vagina	0.005	0.995	0.000
Q52.3 Imperforate hymen	0.005	0.995	0.000
Q52.2 Congenital rectovaginal fistula	0.005	0.995	0.000
Q52.0 Congenital absence of vagina	0.005	0.995	0.000
H35.6 Retinal haemorrhage	0.005	0.995	0.000
Q04.9 Congenital malformation of brain, unspecified	0.005	0.995	0.000
Q04.8 Other specified congenital malformations of brain	0.005	0.995	0.000
Q04.5 Megalencephaly	0.005	0.995	0.000
Q04.4 Septo-optic dysplasia	0.005	0.995	0.000
Q04.3 Other reduction deformities of brain	0.005	0.995	0.000
Q04.2 Holoprosencephaly	0.005	0.995	0.000
Q04.1 Arhinencephaly	0.005	0.995	0.000
Q04.0 Congenital malformations of corpus callosum	0.005	0.995	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.005	0.995	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.005	0.995	0.000
Q45.2 Congenital pancreatic cyst	0.005	0.995	0.000
Q45.1 Annular pancreas	0.005	0.995	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.005	0.995	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.005	0.995	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.005	0.995	0.000
Q51.6 Embryonic cyst of cervix	0.005	0.995	0.000
Q51.5 Agenesis and aplasia of cervix	0.005	0.995	0.000
Q51.4 Unicornate uterus	0.005	0.995	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.005	0.995	0.000
Q51.0 Agenesis and aplasia of uterus	0.005	0.995	0.000
Q53.9 Undescended testicle, unspecified	0.005	0.995	0.000
Q53.2 Undescended testicle, bilateral	0.005	0.995	0.000
Q53.0 Ectopic testis	0.005	0.995	0.000
Q89 Other congenital malformations, not elsewhere classified	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
Q66.0 Talipes equinovarus	0.005	0.995	0.000
Q83 Congenital malformations of breast	0.005	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.005	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.005	0.995	0.000
Q76.7 Congenital malformation of sternum	0.005	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.005	0.995	0.000
Q76.5 Cervical rib	0.005	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.005	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.005	0.995	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.005	0.995	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.005	0.995	0.000
Q40.1 Congenital hiatus hernia	0.005	0.995	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.005	0.995	0.000
E16 Other disorders of pancreatic internal secretion	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Q96.8 Other variants of Turner's syndrome	0.005	0.995	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.005	0.995	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.005	0.995	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.005	0.995	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.005	0.995	0.000
Q96.0 Karyotype 45,X	0.005	0.995	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations