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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs734312
log Bayes Factor = 18.1797
Chromosome 4   position 6,303,354  (GRCh37) Explore rs734312 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.010 0.990
E14.9 Without complications
0.000 0.073 0.927
E10.8 With unspecified complications
0.000 0.078 0.922
E10.3 With ophthalmic complications
0.000 0.099 0.901
E11.1 With ketoacidosis
0.000 0.101 0.899
E11.5 With peripheral circulatory complications
0.000 0.167 0.833
E14.5 With peripheral circulatory complications
0.000 0.212 0.788
E14.6 With other specified complications
0.000 0.216 0.784
E10.5 With peripheral circulatory complications
0.000 0.218 0.782
E10.1 With ketoacidosis
0.000 0.220 0.780
E10.2 With renal complications
0.000 0.221 0.779
E10.0 With coma
0.000 0.222 0.778
E14.8 With unspecified complications
0.000 0.225 0.775
E13 Other specified diabetes mellitus
0.000 0.233 0.767
E10.6 With other specified complications
0.000 0.234 0.765
E14.4 With neurological complications
0.000 0.243 0.757
E11.6 With other specified complications
0.000 0.250 0.750
E10.7 With multiple complications
0.000 0.267 0.733
E14.1 With ketoacidosis
0.000 0.278 0.722
E11.2 With renal complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.284 0.716
E14.0 With coma
0.000 0.284 0.716
E14.2 Withrenal complications
0.000 0.314 0.686
E11.7 With multiple complications
0.000 0.338 0.662
E11.4 With neurological complications
0.000 0.359 0.641
E11.8 With unspecified complications
0.000 0.373 0.627
H36.0 Diabetic retinopathy
0.000 0.388 0.612
E13.9 Without complications
0.000 0.392 0.608
E13.8 With unspecified complications
0.000 0.450 0.550
E13.7 With multiple complications
0.000 0.450 0.550
E13.6 With other specified complications
0.000 0.450 0.550
E13.5 With peripheral circulatory complications
0.000 0.450 0.550
E13.4 With neurological complications
0.000 0.450 0.550
E13.2 With renal complications
0.000 0.450 0.550
E13.1 With ketoacidosis
0.000 0.450 0.550
E13.0 With coma
0.000 0.450 0.550
E11.0 With coma
0.000 0.452 0.548
E13.3 With ophthalmic complications
0.000 0.462 0.537
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E10.4 With neurological complications
0.000 0.503 0.497
H36 Retinal disorders in diseases classified elsewhere
0.000 0.706 0.294
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.789 0.211
Q61 Cystic kidney disease
0.121 0.879 0.000
Q61.2 Polycystic kidney, adult type
0.121 0.879 0.000
Q61.3 Polycystic kidney, unspecified
0.116 0.884 0.000
Q61.0 Congenital single renal cyst
0.105 0.895 0.000
Q60-Q64 Congenital malformations of the urinary system
0.101 0.899 0.000
Q63 Other congenital malformations of kidney
0.095 0.905 0.000
Q61.5 Medullary cystic kidney
0.092 0.908 0.000
Q61.9 Cystic kidney disease, unspecified
0.091 0.909 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.091 0.909 0.000
Q61.8 Other cystic kidney diseases
0.087 0.913 0.000
Q61.1 Polycystic kidney, infantile type
0.087 0.913 0.000
Q64 Other congenital malformations of urinary system
0.086 0.914 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.080 0.920 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.077 0.923 0.000
Q61.4 Renal dysplasia
0.074 0.926 0.000
Q63.0 Accessory kidney
0.069 0.931 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.068 0.932 0.000
Q63.8 Other specified congenital malformations of kidney
0.068 0.932 0.000
Q63.3 Hyperplastic and giant kidney
0.068 0.932 0.000
Q63.2 Ectopic kidney
0.068 0.932 0.000
H30-H36 Disorders of choroid and retina
0.000 0.934 0.066
H34 Retinal vascular occlusions
0.000 0.935 0.065
Q62.1 Atresia and stenosis of ureter
0.062 0.938 0.000
Q64.9 Congenital malformation of urinary system, unspecified
0.062 0.938 0.000
Q64.8 Other specified congenital malformations of urinary system
0.062 0.938 0.000
Q64.6 Congenital diverticulum of bladder
0.062 0.938 0.000
Q64.5 Congenital absence of bladder and urethra
0.062 0.938 0.000
Q64.4 Malformation of urachus
0.062 0.938 0.000
Q64.2 Congenital posterior urethral valves
0.062 0.938 0.000
Q64.1 Exstrophy of urinary bladder
0.062 0.938 0.000
Q64.0 Epispadias
0.062 0.938 0.000
Q64.7 Other congenital malformations of bladder and urethra
0.061 0.939 0.000
H34.8 Other retinal vascular occlusions
0.000 0.940 0.060
Q62.5 Duplication of ureter
0.060 0.940 0.000
H34.2 Other retinal artery occlusions
0.000 0.942 0.058
Q62.8 Other congenital malformations of ureter
0.057 0.943 0.000
Q62.7 Congenital vesico-uretero-renal reflux
0.057 0.943 0.000
Q62.6 Malposition of ureter
0.057 0.943 0.000
Q62.4 Agenesis of ureter
0.057 0.943 0.000
Q62.3 Other obstructive defects of renal pelvis and ureter
0.057 0.943 0.000
Q62.2 Congenital megaloureter
0.057 0.943 0.000
Q62.0 Congenital hydronephrosis
0.057 0.943 0.000
H34.1 Central retinal artery occlusion
0.000 0.949 0.051
Q60 Renal agenesis and other reduction defects of kidney
0.051 0.949 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.949 0.051
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.953 0.047
H34.0 Transient retinal artery occlusion
0.000 0.953 0.047
H30 Chorioretinal inflammation
0.000 0.957 0.043
Q60.6 Potter's syndrome
0.036 0.963 0.000
Q60.5 Renal hypoplasia, unspecified
0.036 0.963 0.000
Q60.4 Renal hypoplasia, bilateral
0.036 0.963 0.000
Q60.3 Renal hypoplasia, unilateral
0.036 0.963 0.000
Q60.1 Renal agenesis, bilateral
0.036 0.963 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.966 0.034
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.966 0.034
H31 Other disorders of choroid
0.000 0.966 0.034
Q60.2 Renal agenesis, unspecified
0.032 0.968 0.000
H30.8 Other chorioretinal inflammations
0.000 0.969 0.031
H30.2 Posterior cyclitis
0.000 0.969 0.031
H30.1 Disseminated chorioretinal inflammation
0.000 0.969 0.031
H30.0 Focal chorioretinal inflammation
0.000 0.969 0.031
H31.1 Choroidal degeneration
0.000 0.973 0.026
H30.9 Chorioretinal inflammation, unspecified
0.000 0.974 0.026
R94.5 Abnormal results of liver function studies
0.000 0.975 0.025
H31.8 Other specified disorders of choroid
0.000 0.975 0.025
H31.4 Choroidal detachment
0.000 0.975 0.024
H31.2 Hereditary choroidal dystrophy
0.000 0.975 0.024
H31.3 Choroidal haemorrhage and rupture
0.000 0.975 0.024
Q60.0 Renal agenesis, unilateral
0.023 0.977 0.000
H31.9 Disorder of choroid, unspecified
0.000 0.980 0.020
R94 Abnormal results of function studies
0.000 0.984 0.016
C01 Malignant neoplasm of base of tongue
0.015 0.985 0.000
H31.0 Chorioretinal scars
0.000 0.985 0.014
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.014 0.986 0.000
R94.2 Abnormal results of pulmonary function studies
0.000 0.986 0.014
C02 Malignant neoplasm of other and unspecified parts of tongue
0.014 0.986 0.000
C02.9 Tongue, unspecified
0.013 0.987 0.000
R94.6 Abnormal results of thyroid function studies
0.000 0.987 0.013
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.987 0.013
R94.4 Abnormal results of kidney function studies
0.000 0.987 0.013
C04 Malignant neoplasm of floor of mouth
0.012 0.987 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.013 0.987 0.000
R94.0 Abnormal results of function studies of central nervous system
0.000 0.988 0.012
R94.3 Abnormal results of cardiovascular function studies
0.000 0.988 0.012
C03 Malignant neoplasm of gum
0.012 0.988 0.000
C12 Malignant neoplasm of pyriform sinus
0.012 0.988 0.000
C09 Malignant neoplasm of tonsil
0.012 0.988 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.000 0.988 0.012
C04.9 Floor of mouth, unspecified
0.011 0.989 0.000
C00 Malignant neoplasm of lip
0.011 0.989 0.000
C02.8 Overlapping lesion of tongue
0.011 0.989 0.000
C11 Malignant neoplasm of nasopharynx
0.011 0.989 0.000
C02.2 Ventral surface of tongue
0.011 0.989 0.000
C13 Malignant neoplasm of hypopharynx
0.010 0.990 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.010 0.990 0.000
C03.1 Lower gum
0.010 0.990 0.000
C03.9 Gum, unspecified
0.010 0.990 0.000
C09.9 Tonsil, unspecified
0.010 0.990 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.010 0.990 0.000
C02.0 Dorsal surface of tongue
0.010 0.990 0.000
C10 Malignant neoplasm of oropharynx
0.010 0.990 0.000
R94.7 Abnormal results of other endocrine function studies
0.000 0.990 0.010
C08 Malignant neoplasm of other and unspecified major salivary glands
0.010 0.990 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.010 0.990 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.000 0.990 0.010
C00.0 External upper lip
0.010 0.990 0.000
C02.4 Lingual tonsil
0.009 0.990 0.000
C07 Malignant neoplasm of parotid gland
0.009 0.990 0.000
C04.0 Anterior floor of mouth
0.009 0.991 0.000
C00.9 Lip, unspecified
0.009 0.991 0.000
C04.8 Overlapping lesion of floor of mouth
0.009 0.991 0.000
C04.1 Lateral floor of mouth
0.009 0.991 0.000
C03.0 Upper gum
0.009 0.991 0.000
C09.8 Overlapping lesion of tonsil
0.009 0.991 0.000
C11.9 Nasopharynx, unspecified
0.009 0.991 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.009 0.991 0.000
C09.0 Tonsillar fossa
0.008 0.991 0.000
C02.1 Border of tongue
0.008 0.991 0.000
G61.8 Other inflammatory polyneuropathies
0.009 0.991 0.000
C00.8 Overlapping lesion of lip
0.008 0.992 0.000
C00.6 Commissure of lip
0.008 0.992 0.000
C00.5 Lip, unspecified, inner aspect
0.008 0.992 0.000
C00.4 Lower lip, inner aspect
0.008 0.992 0.000
C00.3 Upper lip, inner aspect
0.008 0.992 0.000
C00.2 External lip, unspecified
0.008 0.992 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.992 0.008
C05 Malignant neoplasm of palate
0.008 0.992 0.000
C11.8 Overlapping lesion of nasopharynx
0.008 0.992 0.000
C11.3 Anterior wall of nasopharynx
0.008 0.992 0.000
C11.2 Lateral wall of nasopharynx
0.008 0.992 0.000
C11.1 Posterior wall of nasopharynx
0.008 0.992 0.000
C11.0 Superior wall of nasopharynx
0.008 0.992 0.000
Q12 Congenital lens malformations
0.008 0.992 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.008 0.992 0.000
D86 Sarcoidosis
0.008 0.992 0.000
D86.8 Sarcoidosis of other and combined sites
0.008 0.992 0.000
C13.0 Postcricoid region
0.008 0.992 0.000
Q12.0 Congenital cataract
0.008 0.992 0.000
C13.8 Overlapping lesion of hypopharynx
0.008 0.992 0.000
C13.2 Posterior wall of hypopharynx
0.008 0.992 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.008 0.992 0.000
D86.1 Sarcoidosis of lymph nodes
0.008 0.992 0.000
Q18 Other congenital malformations of face and neck
0.008 0.992 0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.007 0.992 0.000
C14.2 Waldeyer's ring
0.007 0.992 0.000
C13.9 Hypopharynx, unspecified
0.007 0.992 0.000
C14.0 Pharynx, unspecified
0.008 0.992 0.000
K75.4 Autoimmune hepatitis
0.000 0.992 0.008
K72.9 Hepatic failure, unspecified
0.000 0.993 0.007
C10.8 Overlapping lesion of oropharynx
0.007 0.993 0.000
C10.4 Branchial cleft
0.007 0.993 0.000
C10.3 Posterior wall of oropharynx
0.007 0.993 0.000
C10.2 Lateral wall of oropharynx
0.007 0.993 0.000
C10.1 Anterior surface of epiglottis
0.007 0.993 0.000
C10.0 Vallecula
0.007 0.993 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.007 0.993 0.000
C08.8 Overlapping lesion of major salivary glands
0.007 0.993 0.000
C08.1 Sublingual gland
0.007 0.993 0.000
C00.1 External lower lip
0.007 0.993 0.000
C08.9 Major salivary gland, unspecified
0.007 0.993 0.000
Q17 Other congenital malformations of ear
0.007 0.993 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.007 0.993 0.000
Q14 Congenital malformations of posterior segment of eye
0.007 0.993 0.000
C10.9 Oropharynx, unspecified
0.007 0.993 0.000
C08.0 Submandibular gland
0.007 0.993 0.000
K35.8 Acute appendicitis, other and unspecified
0.000 0.993 0.007
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.993 0.007
C06 Malignant neoplasm of other and unspecified parts of mouth
0.006 0.993 0.000
D86.0 Sarcoidosis of lung
0.007 0.993 0.000
D86.3 Sarcoidosis of skin
0.007 0.993 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.007 0.993 0.000
G61 Inflammatory polyneuropathy
0.007 0.993 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.007 0.993 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.006 0.993 0.000
Q13 Congenital malformations of anterior segment of eye
0.006 0.993 0.000
Q00-Q07 Congenital malformations of the nervous system
0.006 0.994 0.000
H33 Retinal detachments and breaks
0.000 0.994 0.006
Q15 Other congenital malformations of eye
0.006 0.994 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.006 0.994 0.000
C05.8 Overlapping lesion of palate
0.006 0.994 0.000
C05.2 Uvula
0.006 0.994 0.000
Q12.9 Congenital lens malformation, unspecified
0.006 0.994 0.000
Q12.8 Other congenital lens malformations
0.006 0.994 0.000
Q12.4 Spherophakia
0.006 0.994 0.000
Q12.3 Congenital aphakia
0.006 0.994 0.000
Q12.2 Coloboma of lens
0.006 0.994 0.000
Q12.1 Congenital displaced lens
0.006 0.994 0.000
G61.0 Guillain-Barre syndrome
0.006 0.994 0.000
Q17.5 Prominent ear
0.006 0.994 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.994 0.006
Q10.0 Congenital ptosis
0.006 0.994 0.000
Q18.9 Congenital malformation of face and neck, unspecified
0.006 0.994 0.000
Q18.8 Other specified congenital malformations of face and neck
0.006 0.994 0.000
Q18.7 Microcheilia
0.006 0.994 0.000
Q18.6 Macrocheilia
0.006 0.994 0.000
Q18.5 Microstomia
0.006 0.994 0.000
Q18.4 Macrostomia
0.006 0.994 0.000
Q18.3 Webbing of neck
0.006 0.994 0.000
Q18.2 Other branchial cleft malformations
0.006 0.994 0.000
C05.1 Soft palate
0.006 0.994 0.000
Q35-Q37 Cleft lip and cleft palate
0.006 0.994 0.000
Q14.1 Congenital malformation of retina
0.006 0.994 0.000
H33.1 Retinoschisis and retinal cysts
0.000 0.994 0.006
C05.9 Palate, unspecified
0.005 0.994 0.000
K75 Other inflammatory liver diseases
0.000 0.994 0.006
D80-D89 Certain disorders involving the immune mechanism
0.006 0.994 0.000
E40-E46 Malnutrition
0.000 0.994 0.006
K72 Hepatic failure, not elsewhere classified
0.000 0.994 0.006
Q31 Congenital malformations of larynx
0.005 0.994 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.995 0.005
C05.0 Hard palate
0.005 0.995 0.000
Q18.1 Preauricular sinus and cyst
0.005 0.995 0.000
Q17.9 Congenital malformation of ear, unspecified
0.005 0.995 0.000
Q17.8 Other specified congenital malformations of ear
0.005 0.995 0.000
Q17.4 Misplaced ear
0.005 0.995 0.000
Q17.3 Other misshapen ear
0.005 0.995 0.000
Q17.2 Microtia
0.005 0.995 0.000
Q17.1 Macrotia
0.005 0.995 0.000
Q17.0 Accessory auricle
0.005 0.995 0.000
G60.0 Hereditary motor and sensory neuropathy
0.005 0.995 0.000
Q10.7 Congenital malformation of orbit
0.005 0.995 0.000
Q10.6 Other congenital malformations of lachrymal apparatus
0.005 0.995 0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct
0.005 0.995 0.000
Q10.4 Absence and agenesis of lachrymal apparatus
0.005 0.995 0.000
Q10.3 Other congenital malformations of eyelid
0.005 0.995 0.000
Q10.2 Congenital entropion
0.005 0.995 0.000
Q10.1 Congenital ectropion
0.005 0.995 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.005 0.995 0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified
0.005 0.995 0.000
Q14.8 Other congenital malformations of posterior segment of eye
0.005 0.995 0.000
Q14.3 Congenital malformation of choroid
0.005 0.995 0.000
Q14.2 Congenital malformation of optic disk
0.005 0.995 0.000
Q14.0 Congenital malformation of vitreous humour
0.005 0.995 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.995 0.005
Q30 Congenital malformations of nose
0.005 0.995 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.005 0.995 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.005 0.995 0.000
C06.1 Vestibule of mouth
0.005 0.995 0.000
D80 Immunodeficiency with predominantly antibody defects
0.005 0.995 0.000
E65 Localised adiposity
0.000 0.995 0.005
E16.1 Other hypoglycaemia
0.000 0.995 0.005
Q07 Other congenital malformations of nervous system
0.005 0.995 0.000
D82 Immunodeficiency associated with other major defects
0.005 0.995 0.000
Q34 Other congenital malformations of respiratory system
0.005 0.995 0.000
Q33 Congenital malformations of lung
0.005 0.995 0.000
Q32 Congenital malformations of trachea and bronchus
0.005 0.995 0.000
G61.1 Serum neuropathy
0.005 0.995 0.000
K75.9 Inflammatory liver disease, unspecified
0.000 0.995 0.005
Q06 Other congenital malformations of spinal cord
0.005 0.995 0.000
K75.0 Abscess of liver
0.000 0.995 0.005
K74.3 Primary biliary cirrhosis
0.000 0.995 0.005
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.000 0.995 0.005
Q13.9 Congenital malformation of anterior segment of eye, unspecified
0.005 0.995 0.000
Q13.8 Other congenital malformations of anterior segment of eye
0.005 0.995 0.000
Q13.5 Blue sclera
0.005 0.995 0.000
Q13.4 Other congenital corneal malformations
0.005 0.995 0.000
Q13.3 Congenital corneal opacity
0.005 0.995 0.000
Q13.2 Other congenital malformations of iris
0.005 0.995 0.000
Q13.1 Absence of iris
0.005 0.995 0.000
Q13.0 Coloboma of iris
0.005 0.995 0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified
0.005 0.995 0.000
Q16.5 Congenital malformation of inner ear
0.005 0.995 0.000
Q16.4 Other congenital malformations of middle ear
0.005 0.995 0.000
Q16.3 Congenital malformation of ear ossicles
0.005 0.995 0.000
Q16.2 Absence of eustachian tube
0.005 0.995 0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)
0.005 0.995 0.000
Q16.0 Congenital absence of (ear) auricle
0.005 0.995 0.000
C06.9 Mouth, unspecified
0.005 0.995 0.000
W13.9 Unspecified place
0.000 0.995 0.005
Q04 Other congenital malformations of brain
0.005 0.995 0.000
Q01 Encephalocele
0.005 0.995 0.000
Q00 Anencephaly and similar malformations
0.005 0.995 0.000
Q02 Microcephaly
0.005 0.995 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.995 0.005
Q03 Congenital hydrocephalus
0.005 0.995 0.000
D86.9 Sarcoidosis, unspecified
0.005 0.995 0.000
Q11.3 Macrophthalmos
0.005 0.995 0.000
Q11.2 Microphthalmos
0.005 0.995 0.000
Q11.0 Cystic eyeball
0.005 0.995 0.000
Q15.9 Congenital malformation of eye, unspecified
0.005 0.995 0.000
Q15.8 Other specified congenital malformations of eye
0.005 0.995 0.000
Q31.0 Web of larynx
0.005 0.995 0.000
Q05 Spina bifida
0.005 0.995 0.000
G31.8 Other specified degenerative diseases of nervous system
0.005 0.995 0.000
D82.1 Di George's syndrome
0.004 0.995 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.995 0.004
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.995 0.004
E16.4 Abnormal secretion of gastrin
0.000 0.995 0.004
E16.3 Increased secretion of glucagon
0.000 0.995 0.004
Q15.0 Congenital glaucoma
0.004 0.996 0.000
Q11.1 Other anophthalmos
0.004 0.996 0.000
A04.8 Other specified bacterial intestinal infections
0.000 0.996 0.004
K72.1 Chronic hepatic failure
0.000 0.996 0.004
Q36 Cleft lip
0.004 0.996 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.004 0.996 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.004 0.996 0.000
N81.5 Vaginal enterocele
0.004 0.996 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.996 0.004
Q37 Cleft palate with cleft lip
0.004 0.996 0.000
K70-K77 Diseases of liver
0.000 0.996 0.004
K75.2 Nonspecific reactive hepatitis
0.000 0.996 0.004
K75.1 Phlebitis of portal vein
0.000 0.996 0.004
D81 Combined immunodeficiencies
0.004 0.996 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.004 0.996 0.000
D84 Other immunodeficiencies
0.004 0.996 0.000
Q80-Q89 Other congenital malformations
0.004 0.996 0.000
D83 Common variable immunodeficiency
0.004 0.996 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.996 0.004
E45 Retarded development following protein-energy malnutrition
0.000 0.996 0.004
E43 Unspecified severe protein-energy malnutrition
0.000 0.996 0.004
E42 Marasmic kwashiorkor
0.000 0.996 0.004
E41 Nutritional marasmus
0.000 0.996 0.004
E40 Kwashiorkor
0.000 0.996 0.004
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.004 0.996 0.000
Q07.8 Other specified congenital malformations of nervous system
0.004 0.996 0.000
Q35 Cleft palate
0.004 0.996 0.000
Q31.9 Congenital malformation of larynx, unspecified
0.004 0.996 0.000
Q31.8 Other congenital malformations of larynx
0.004 0.996 0.000
Q31.5 Congenital laryngomalacia
0.004 0.996 0.000
Q31.4 Congenital laryngeal stridor
0.004 0.996 0.000
Q31.3 Laryngocele
0.004 0.996 0.000
Q31.2 Laryngeal hypoplasia
0.004 0.996 0.000
Q31.1 Congenital subglottic stenosis
0.004 0.996 0.000
G60 Hereditary and idiopathic neuropathy
0.004 0.996 0.000
Q30.3 Congenital perforated nasal septum
0.004 0.996 0.000
E67 Other hyperalimentation
0.000 0.996 0.004
E68 Sequelae of hyperalimentation
0.000 0.996 0.004
K74.0 Hepatic fibrosis
0.000 0.996 0.004
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.004 0.996 0.000
Q90 Down's syndrome
0.004 0.996 0.000
C06.0 Cheek mucosa
0.004 0.996 0.001
F12.1 Harmful use
0.000 0.996 0.004
Q99 Other chromosome abnormalities, not elsewhere classified
0.004 0.996 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.004 0.996 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.004 0.996 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.004 0.996 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.004 0.996 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.004 0.996 0.000
C06.2 Retromolar area
0.003 0.996 0.001
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.004 0.996 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.996 0.004
Q06.8 Other specified congenital malformations of spinal cord
0.004 0.996 0.000
Q30.9 Congenital malformation of nose, unspecified
0.004 0.996 0.000
Q30.8 Other congenital malformations of nose
0.004 0.996 0.000
Q30.2 Fissured, notched and cleft nose
0.004 0.996 0.000
Q30.1 Agenesis and underdevelopment of nose
0.004 0.996 0.000
Q30.0 Choanal atresia
0.004 0.996 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.004 0.996 0.000
H35.9 Retinal disorder, unspecified
0.000 0.996 0.004
D80.8 Other immunodeficiencies with predominantly antibody defects
0.004 0.996 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.004 0.996 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.004 0.996 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.004 0.996 0.000
M24.01 Loose body in joint (Shoulder region)
0.000 0.996 0.004
C71.1 Frontal lobe
0.000 0.996 0.004
Q07.9 Congenital malformation of nervous system, unspecified
0.004 0.996 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.996 0.004
D82.9 Immunodeficiency associated with major defect, unspecified
0.004 0.996 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.004 0.996 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.004 0.996 0.000
D82.2 Immunodeficiency with short-limbed stature
0.004 0.996 0.000
D82.0 Wiskott-Aldrich syndrome
0.004 0.996 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.004 0.996 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.004 0.996 0.000
Q32.4 Other congenital malformations of bronchus
0.004 0.996 0.000
Q32.3 Congenital stenosis of bronchus
0.004 0.996 0.000
Q32.2 Congenital bronchomalacia
0.004 0.996 0.000
Q32.1 Other congenital malformations of trachea
0.004 0.996 0.000
Q32.0 Congenital tracheomalacia
0.004 0.996 0.000
Q33.9 Congenital malformation of lung, unspecified
0.004 0.996 0.000
Q33.8 Other congenital malformations of lung
0.004 0.996 0.000
Q33.6 Hypoplasia and dysplasia of lung
0.004 0.996 0.000
Q33.5 Ectopic tissue in lung
0.004 0.996 0.000
Q33.4 Congenital bronchiectasis
0.004 0.996 0.000
Q33.3 Agenesis of lung
0.004 0.996 0.000
Q33.2 Sequestration of lung
0.004 0.996 0.000
Q33.1 Accessory lobe of lung
0.004 0.996 0.000
Q33.0 Congenital cystic lung
0.004 0.996 0.000
Q34.9 Congenital malformation of respiratory system, unspecified
0.004 0.996 0.000
Q34.8 Other specified congenital malformations of respiratory system
0.004 0.996 0.000
Q34.1 Congenital cyst of mediastinum
0.004 0.996 0.000
Q34.0 Anomaly of pleura
0.004 0.996 0.000
Q05.4 Unspecified spina bifida with hydrocephalus
0.004 0.996 0.000
Q06.9 Congenital malformation of spinal cord, unspecified
0.004 0.996 0.000
Q06.4 Hydromyelia
0.004 0.996 0.000
Q06.3 Other congenital cauda equina malformations
0.004 0.996 0.000
Q06.2 Diastematomyelia
0.004 0.996 0.000
Q06.1 Hypoplasia and dysplasia of spinal cord
0.004 0.996 0.000
Q06.0 Amyelia
0.004 0.996 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.004 0.996 0.000
Q05.7 Lumbar spina bifida without hydrocephalus
0.004 0.996 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.004 0.996 0.000
Q04.6 Congenital cerebral cysts
0.004 0.996 0.000
K71 Toxic liver disease
0.000 0.996 0.004
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.004 0.996 0.000
K72.0 Acute and subacute hepatic failure
0.000 0.996 0.004
Q07.0 Arnold-Chiari syndrome
0.004 0.996 0.000
Q00.2 Iniencephaly
0.004 0.996 0.000
Q00.1 Craniorachischisis
0.004 0.996 0.000
Q00.0 Anencephaly
0.004 0.996 0.000
Q01.9 Encephalocele, unspecified
0.004 0.996 0.000
Q01.8 Encephalocele of other sites
0.004 0.996 0.000
Q01.2 Occipital encephalocele
0.004 0.996 0.000
Q01.1 Nasofrontal encephalocele
0.004 0.996 0.000
Q01.0 Frontal encephalocele
0.004 0.996 0.000
Q04.9 Congenital malformation of brain, unspecified
0.004 0.996 0.000
Q04.5 Megalencephaly
0.004 0.996 0.000
Q04.4 Septo-optic dysplasia
0.004 0.996 0.000
Q04.3 Other reduction deformities of brain
0.004 0.996 0.000
Q04.2 Holoprosencephaly
0.004 0.996 0.000
Q04.1 Arhinencephaly
0.004 0.996 0.000
Q04.0 Congenital malformations of corpus callosum
0.004 0.996 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.004 0.996 0.000
Q03.9 Congenital hydrocephalus, unspecified
0.003 0.996 0.000
Q03.8 Other congenital hydrocephalus
0.003 0.996 0.000
Q03.1 Atresia of foramina of Magendie and Luschka
0.003 0.996 0.000
D84.1 Defects in the complement system
0.004 0.996 0.000
Q05.8 Sacral spina bifida without hydrocephalus
0.003 0.996 0.000
Q05.6 Thoracic spina bifida without hydrocephalus
0.003 0.996 0.000
Q05.5 Cervical spina bifida without hydrocephalus
0.003 0.996 0.000
Q05.3 Sacral spina bifida with hydrocephalus
0.003 0.996 0.000
Q05.2 Lumbar spina bifida with hydrocephalus
0.003 0.996 0.000
Q05.1 Thoracic spina bifida with hydrocephalus
0.003 0.996 0.000
Q05.0 Cervical spina bifida with hydrocephalus
0.003 0.996 0.000
Q04.8 Other specified congenital malformations of brain
0.003 0.996 0.000
Q03.0 Malformations of aqueduct of Sylvius
0.003 0.996 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.996 0.004
Q96 Turner's syndrome
0.003 0.996 0.000
D84.8 Other specified immunodeficiencies
0.003 0.996 0.000
H33.0 Retinal detachment with retinal break
0.000 0.996 0.004
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.000 0.996 0.003
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.000 0.996 0.003
H35 Other retinal disorders
0.000 0.996 0.003
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.003 0.997 0.000
H33.4 Traction detachment of retina
0.000 0.997 0.003
Q36.9 Cleft lip, unilateral
0.003 0.997 0.000
Q36.1 Cleft lip, medial
0.003 0.997 0.000
Q36.0 Cleft lip, bilateral
0.003 0.997 0.000
W13 Fall from, out of or through building or structure
0.000 0.997 0.003
D89.0 Polyclonal hypergammaglobulinaemia
0.003 0.997 0.000
G31.0 Circumscribed brain atrophy
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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