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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73435406
log Bayes Factor = 5.06374
Chromosome 18   position 46,440,764  (GRCh37) Explore rs73435406 on Ensembl!
Variant rs73435406 is part of Cluster X0061

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
G20-G26 Extrapyramidal and movement disorders
0.991 0.009 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.990 0.010 0.000
G40-G47 Episodic and paroxysmal disorders
0.987 0.013 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.987 0.013 0.000
Chapter VIII Diseases of the ear and mastoid process
0.986 0.014 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.985 0.015 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.983 0.017 0.000
T66-T78 Other and unspecified effects of external causes
0.982 0.018 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.982 0.018 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.980 0.020 0.000
G40 Epilepsy
0.979 0.021 0.000
G20 Parkinson's disease
0.977 0.023 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.976 0.024 0.000
T39.1 4-Aminophenol derivatives
0.971 0.029 0.000
T90 Sequelae of injuries of head
0.969 0.031 0.000
Y42.5 Other oestrogens and progestogens
0.961 0.039 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.955 0.045 0.000
B07 Viral warts
0.954 0.046 0.000
T78 Adverse effects, not elsewhere classified
0.953 0.047 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.951 0.049 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.945 0.055 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.942 0.058 0.000
T92 Sequelae of injuries of upper limb
0.936 0.064 0.000
F41 Other anxiety disorders
0.935 0.065 0.000
H65-H75 Diseases of middle ear and mastoid
0.932 0.068 0.000
F41.9 Anxiety disorder, unspecified
0.931 0.069 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.923 0.077 0.000
T78.4 Allergy, unspecified
0.923 0.077 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.914 0.086 0.000
G41 Status epilepticus
0.911 0.089 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.908 0.092 0.000
Y44 Agents primarily affecting blood constituents
0.903 0.097 0.000
G35 Multiple sclerosis
0.902 0.098 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.901 0.099 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.893 0.107 0.000
B02 Zoster [herpes zoster]
0.892 0.108 0.000
S70-S79 Injuries to the hip and thigh
0.891 0.109 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.889 0.111 0.000
H66 Suppurative and unspecified otitis media
0.886 0.114 0.000
F00 Dementia in Alzheimer's disease
0.883 0.117 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.878 0.122 0.000
B15-B19 Viral hepatitis
0.875 0.125 0.000
S40-S49 Injuries to the shoulder and upper arm
0.864 0.136 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.863 0.137 0.000
F43 Reaction to severe stress, and adjustment disorders
0.863 0.137 0.000
H60-H62 Diseases of external ear
0.862 0.138 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.862 0.138 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.855 0.145 0.000
B50-B64 Protozoal diseases
0.853 0.147 0.000
F30-F39 Mood [affective] disorders
0.853 0.147 0.000
B91 Sequelae of poliomyelitis
0.848 0.152 0.000
T00-T07 Injuries involving multiple body regions
0.848 0.152 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.843 0.157 0.000
G30-G32 Other degenerative diseases of the nervous system
0.842 0.158 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.840 0.160 0.000
F30 Manic episode
0.840 0.160 0.000
T39.0 Salicylates
0.839 0.161 0.000
G25 Other extrapyramidal and movement disorders
0.837 0.163 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.833 0.167 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.829 0.171 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.828 0.172 0.000
T71 Asphyxiation
0.827 0.173 0.000
G41.9 Status epilepticus, unspecified
0.826 0.174 0.000
V80-V89 Other land transport accidents
0.825 0.175 0.000
F30.9 Manic episode, unspecified
0.823 0.177 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.823 0.177 0.000
F02 Dementia in other diseases classified elsewhere
0.822 0.178 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.820 0.180 0.000
F44 Dissociative [conversion] disorders
0.820 0.180 0.000
H90-H95 Other disorders of ear
0.820 0.180 0.000
X10-X19 Contact with heat and hot substances
0.819 0.181 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.814 0.186 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.814 0.186 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.810 0.190 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.809 0.191 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.808 0.192 0.000
F60-F69 Disorders of adult personality and behaviour
0.806 0.194 0.000
F42 Obsessive-compulsive disorder
0.800 0.200 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.799 0.201 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.798 0.202 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.798 0.202 0.000
W50-W64 Exposure to animate mechanical forces
0.797 0.203 0.000
H80-H83 Diseases of inner ear
0.795 0.205 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.795 0.205 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.795 0.205 0.000
T90.1 Sequelae of open wound of head
0.794 0.206 0.000
T79-T79 Certain early complications of trauma
0.793 0.207 0.000
H74 Other disorders of middle ear and mastoid
0.791 0.209 0.000
T70 Effects of air pressure and water pressure
0.791 0.209 0.000
B35-B49 Mycoses
0.787 0.213 0.000
H71 Cholesteatoma of middle ear
0.785 0.215 0.000
T90.9 Sequelae of unspecified injury of head
0.784 0.216 0.000
G21 Secondary Parkinsonism
0.783 0.217 0.000
V10-V19 Pedal cyclist injured in transport accident
0.782 0.218 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.782 0.218 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.781 0.219 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.781 0.219 0.000
A63.0 Anogenital (venereal) warts
0.781 0.219 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.780 0.220 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.779 0.221 0.000
H60 Otitis externa
0.778 0.222 0.000
B02.9 Zoster without complication
0.774 0.226 0.000
Y44.2 Anticoagulants
0.774 0.226 0.000
S72 Fracture of femur
0.773 0.227 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.771 0.229 0.000
T95 Sequelae of burns, corrosions and frostbite
0.769 0.231 0.000
G40.5 Special epileptic syndromes
0.766 0.233 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.766 0.233 0.000
F03 Unspecified dementia
0.763 0.237 0.000
F99-F99 Unspecified mental disorder
0.763 0.237 0.000
B17 Other acute viral hepatitis
0.763 0.237 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.762 0.238 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.762 0.238 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.759 0.241 0.000
H70 Mastoiditis and related conditions
0.758 0.242 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.758 0.242 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.757 0.243 0.000
Y42.1 Thyroid hormones and substitutes
0.757 0.243 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.756 0.244 0.000
V01-V09 Pedestrian injured in transport accident
0.755 0.245 0.000
T92.0 Sequelae of open wound of upper limb
0.754 0.246 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.754 0.246 0.000
T66 Unspecified effects of radiation
0.753 0.246 0.000
S32 Fracture of lumbar spine and pelvis
0.752 0.248 0.000
F43.2 Adjustment disorders
0.751 0.249 0.000
G00 Bacterial meningitis, not elsewhere classified
0.751 0.249 0.000
G30 Alzheimer's disease
0.750 0.249 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.750 0.250 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.748 0.252 0.000
V95-V97 Air and space transport accidents
0.748 0.252 0.000
B18 Chronic viral hepatitis
0.747 0.253 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.747 0.253 0.000
V40-V49 Car occupant injured in transport accident
0.745 0.255 0.000
A80-A89 Viral infections of the central nervous system
0.744 0.255 0.000
H81 Disorders of vestibular function
0.744 0.256 0.000
G41.0 Grand mal status epilepticus
0.743 0.257 0.000
T14 Injury of unspecified body region
0.743 0.257 0.000
H66.3 Other chronic suppurative otitis media
0.743 0.257 0.000
S71 Open wound of hip and thigh
0.743 0.257 0.000
B02.2 Zoster with other nervous system involvement
0.742 0.258 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.742 0.258 0.000
S00-S09 Injuries to the head
0.741 0.259 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.740 0.259 0.000
W20-W49 Exposure to inanimate mechanical forces
0.740 0.260 0.000
G40.9 Epilepsy, unspecified
0.738 0.262 0.000
Y42.7 Androgens and anabolic congeners
0.737 0.263 0.000
T01 Open wounds involving multiple body regions
0.736 0.264 0.000
H66.9 Otitis media, unspecified
0.736 0.264 0.000
B35 Dermatophytosis
0.736 0.264 0.000
B99-B99 Other infectious diseases
0.735 0.265 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.735 0.265 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.734 0.266 0.000
Y59 Other and unspecified vaccines and biological substances
0.732 0.268 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.731 0.269 0.000
F48 Other neurotic disorders
0.731 0.269 0.000
F01 Vascular dementia
0.731 0.269 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.729 0.271 0.000
G46.7 Other lacunar syndromes
0.728 0.272 0.000
H66.0 Acute suppurative otitis media
0.726 0.274 0.000
S20-S29 Injuries to the thorax
0.725 0.275 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.719 0.281 0.000
A65-A69 Other spirochaetal diseases
0.718 0.282 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
T25 Burn and corrosion of ankle and foot
0.715 0.285 0.000
T75 Effects of other external causes
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
Y57 Other and unspecified drugs and medicaments
0.713 0.287 0.000
T43.2 Other and unspecified antidepressants
0.712 0.288 0.000
S50-S59 Injuries to the elbow and forearm
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.711 0.289 0.000
G23 Other degenerative diseases of basal ganglia
0.711 0.289 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.711 0.289 0.000
G22 Parkinsonism in diseases classified elsewhere
0.711 0.289 0.000
F43.1 Posttraumatic stress disorder
0.711 0.289 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.710 0.290 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.710 0.290 0.000
T39.4 Antirheumatics, not elsewhere classified
0.710 0.290 0.000
T39.2 Pyrazolone derivatives
0.710 0.290 0.000
B59 Pneumocystosis
0.709 0.291 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.709 0.291 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.707 0.293 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
Y58 Bacterial vaccines
0.706 0.294 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.706 0.294 0.000
T21 Burn and corrosion of trunk
0.706 0.294 0.000
T78.3 Angioneurotic oedema
0.705 0.295 0.000
Y42.9 Other and unspecified hormone antagonists
0.705 0.295 0.000
Y42.4 Oral contraceptives
0.705 0.295 0.000
Y42.2 Antithyroid drugs
0.705 0.295 0.000
G24 Dystonia
0.705 0.295 0.000
T74 Maltreatment syndromes
0.704 0.296 0.000
T73 Effects of other deprivation
0.704 0.296 0.000
T69 Other effects of reduced temperature
0.704 0.296 0.000
T67 Effects of heat and light
0.704 0.296 0.000
Y44.5 Thrombolytic drugs
0.703 0.297 0.000
B06 Rubella [German measles]
0.702 0.298 0.000
B05 Measles
0.702 0.298 0.000
B01 Varicella [chickenpox]
0.702 0.298 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.702 0.298 0.000
B04 Monkeypox
0.702 0.298 0.000
B03 Smallpox
0.702 0.298 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.702 0.298 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.702 0.298 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.702 0.298 0.000
H93 Other disorders of ear, not elsewhere classified
0.702 0.298 0.000
F41.8 Other specified anxiety disorders
0.701 0.299 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
T90.4 Sequelae of injury of eye and orbit
0.701 0.299 0.000
H81.0 Meniere's disease
0.700 0.300 0.000
F09 Unspecified organic or symptomatic mental disorder
0.700 0.300 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.700 0.300 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.700 0.300 0.000
G46.4 Cerebellar stroke syndrome
0.699 0.300 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.699 0.301 0.000
S40 Superficial injury of shoulder and upper arm
0.699 0.301 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.698 0.302 0.000
T98 Sequelae of other and unspecified effects of external causes
0.697 0.303 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.697 0.303 0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases
0.696 0.304 0.000
F02.3 Dementia in Parkinson's disease
0.696 0.304 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.695 0.305 0.000
B35.3 Tinea pedis
0.695 0.305 0.000
T90.3 Sequelae of injury of cranial nerves
0.695 0.305 0.000
T90.0 Sequelae of superficial injury of head
0.695 0.305 0.000
H65 Nonsuppurative otitis media
0.694 0.306 0.000
F41.1 Generalised anxiety disorder
0.694 0.306 0.000
S09 Other and unspecified injuries of head
0.693 0.307 0.000
F05.9 Delirium, unspecified
0.691 0.309 0.000
T43.6 Psychostimulants with abuse potential
0.691 0.309 0.000
Y48 Anaesthetics and therapeutic gases
0.689 0.311 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.688 0.312 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.688 0.312 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
B50 Plasmodium falciparum malaria
0.685 0.315 0.000
T78.9 Adverse effect, unspecified
0.683 0.317 0.000
T78.8 Other adverse effects, not elsewhere classified
0.683 0.317 0.000
B17.1 Acute hepatitis C
0.682 0.318 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.682 0.318 0.000
X58 Exposure to other specified factors
0.682 0.318 0.000
S32.4 Fracture of acetabulum
0.682 0.318 0.000
T14.0 Superficial injury of unspecified body region
0.681 0.319 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.681 0.319 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.679 0.321 0.000
F44.5 Dissociative convulsions
0.678 0.322 0.000
T43.9 Psychotropic drug, unspecified
0.678 0.322 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.678 0.322 0.000
F64 Gender identity disorders
0.677 0.323 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.675 0.324 0.000
G36 Other acute disseminated demyelination
0.675 0.325 0.000
X50-X57 Overexertion, travel and privation
0.674 0.326 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.674 0.326 0.000
H66.4 Suppurative otitis media, unspecified
0.674 0.326 0.000
B65-B83 Helminthiases
0.673 0.327 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.672 0.327 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.671 0.329 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.671 0.329 0.000
F41.3 Other mixed anxiety disorders
0.670 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.670 0.330 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.669 0.331 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.668 0.331 0.000
H68 Eustachian salpingitis and obstruction
0.668 0.331 0.000
H67 Otitis media in diseases classified elsewhere
0.668 0.331 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.668 0.332 0.000
F30.0 Hypomania
0.668 0.332 0.000
S36 Injury of intra-abdominal organs
0.668 0.332 0.000
S70 Superficial injury of hip and thigh
0.668 0.332 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.666 0.333 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.666 0.333 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.666 0.334 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.666 0.334 0.000
Y55.4 Expectorants
0.665 0.335 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.665 0.335 0.000
G44 Other headache syndromes
0.665 0.335 0.000
B02.3 Zoster ocular disease
0.664 0.336 0.000
G37 Other demyelinating diseases of central nervous system
0.662 0.338 0.000
Y88 Sequelae of surgical and medical care as external cause
0.661 0.339 0.000
H60.9 Otitis externa, unspecified
0.661 0.339 0.000
F45 Somatoform disorders
0.660 0.340 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.660 0.340 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.659 0.341 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.658 0.342 0.000
S09.9 Unspecified injury of head
0.658 0.342 0.000
T01.2 Open wounds involving multiple regions of upper limb(s)
0.656 0.344 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.656 0.344 0.000
T20 Burn and corrosion of head and neck
0.656 0.344 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.656 0.344 0.000
B90 Sequelae of tuberculosis
0.656 0.344 0.000
B92 Sequelae of leprosy
0.656 0.344 0.000
T23 Burn and corrosion of wrist and hand
0.656 0.344 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.654 0.346 0.000
F30.2 Mania with psychotic symptoms
0.654 0.346 0.000
T70.3 Caisson disease [decompression sickness]
0.654 0.346 0.000
G41.8 Other status epilepticus
0.653 0.347 0.000
G41.2 Complex partial status epilepticus
0.653 0.347 0.000
G41.1 Petit mal status epilepticus
0.653 0.347 0.000
H90 Conductive and sensorineural hearing loss
0.652 0.348 0.000
G30.9 Alzheimer's disease, unspecified
0.652 0.348 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.652 0.348 0.000
H60.0 Abscess of external ear
0.651 0.349 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.649 0.351 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.649 0.351 0.000
Y00-Y09 Assault
0.648 0.352 0.000
G00.9 Bacterial meningitis, unspecified
0.648 0.352 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.647 0.353 0.000
Y44.7 Plasma substitutes
0.647 0.353 0.000
Y44.6 Natural blood and blood products
0.647 0.353 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.647 0.353 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.647 0.353 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.647 0.353 0.000
H69 Other disorders of Eustachian tube
0.647 0.353 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.646 0.354 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.646 0.354 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.646 0.354 0.000
F39 Unspecified mood [affective] disorder
0.645 0.355 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.644 0.356 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.644 0.356 0.000
F43.9 Reaction to severe stress, unspecified
0.644 0.356 0.000
H60.5 Acute otitis externa, non-infective
0.643 0.357 0.000
B19 Unspecified viral hepatitis
0.642 0.358 0.000
H81.1 Benign paroxysmal vertigo
0.641 0.359 0.000
A59 Trichomoniasis
0.641 0.359 0.000
A56 Other sexually transmitted chlamydial diseases
0.641 0.359 0.000
A54 Gonococcal infection
0.641 0.359 0.000
A53 Other and unspecified syphilis
0.641 0.359 0.000
A52 Late syphilis
0.641 0.359 0.000
A51 Early syphilis
0.641 0.359 0.000
A50 Congenital syphilis
0.641 0.359 0.000
A64 Unspecified sexually transmitted disease
0.641 0.359 0.000
A58 Granuloma inguinale
0.641 0.359 0.000
A57 Chancroid
0.641 0.359 0.000
A55 Chlamydial lymphogranuloma (venereum)
0.641 0.359 0.000
B02.8 Zoster with other complications
0.639 0.361 0.000
B02.7 Disseminated zoster
0.639 0.361 0.000
B02.1 Zoster meningitis
0.639 0.361 0.000
B02.0 Zoster encephalitis
0.639 0.361 0.000
S78 Traumatic amputation of hip and thigh
0.638 0.361 0.000
S77 Crushing injury of hip and thigh
0.638 0.361 0.000
S75 Injury of blood vessels at hip and thigh level
0.638 0.361 0.000
S74 Injury of nerves at hip and thigh level
0.638 0.361 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.638 0.362 0.000
E20-E35 Disorders of other endocrine glands
0.638 0.362 0.000
S71.1 Open wound of thigh
0.637 0.363 0.000
S31 Open wound of abdomen, lower back and pelvis
0.636 0.364 0.000
B18.2 Chronic viral hepatitis C
0.636 0.364 0.000
Y79.2 Prosthetic and other implants, materials and accessory devices
0.636 0.364 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.636 0.364 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.635 0.365 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.634 0.366 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.633 0.367 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.633 0.367 0.000
X12 Contact with other hot fluids
0.633 0.367 0.000
H70.8 Other mastoiditis and related conditions
0.633 0.367 0.000
S32.40 Fracture of acetabulum (closed)
0.632 0.368 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.630 0.370 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.630 0.370 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.630 0.370 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.630 0.370 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.630 0.370 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.630 0.370 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.630 0.370 0.000
T44.0 Anticholinesterase agents
0.630 0.370 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.629 0.371 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.629 0.371 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.627 0.372 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.627 0.373 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.626 0.373 0.000
T00 Superficial injuries involving multiple body regions
0.626 0.373 0.000
S37 Injury of urinary and pelvic organs
0.625 0.375 0.000
W51 Striking against or bumped into by another person
0.624 0.376 0.000
G30.8 Other Alzheimer's disease
0.624 0.376 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.624 0.376 0.000
T45.5 Anticoagulants
0.624 0.376 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.623 0.377 0.000
H92 Otalgia and effusion of ear
0.622 0.378 0.000
B08.1 Molluscum contagiosum
0.621 0.379 0.000
S48 Traumatic amputation of shoulder and upper arm
0.620 0.380 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.620 0.380 0.000
S44 Injury of nerves at shoulder and upper arm level
0.620 0.380 0.000
S47 Crushing injury of shoulder and upper arm
0.620 0.380 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.620 0.380 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.619 0.380 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.619 0.381 0.000
Y80 Physical medicine devices associated with adverse incidents
0.619 0.381 0.000
Y78 Radiological devices associated with adverse incidents
0.619 0.381 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.619 0.381 0.000
Y75 Neurological devices associated with adverse incidents
0.619 0.381 0.000
Y74 General hospital and personal-use devices associated with adverse incidents
0.619 0.381 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.619 0.381 0.000
Y72 Otorhinolaryngological devices associated with adverse incidents
0.619 0.381 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.619 0.381 0.000
F43.8 Other reactions to severe stress
0.619 0.381 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.618 0.382 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.618 0.382 0.000
G46.6 Pure sensory lacunar syndrome
0.618 0.382 0.000
G46.5 Pure motor lacunar syndrome
0.618 0.382 0.000
G46.3 Brain stem stroke syndrome
0.618 0.382 0.000
G46.2 Posterior cerebral artery syndrome
0.618 0.382 0.000
G46.1 Anterior cerebral artery syndrome
0.618 0.382 0.000
G46.0 Middle cerebral artery syndrome
0.618 0.382 0.000
S00 Superficial injury of head
0.617 0.383 0.000
F34 Persistent mood [affective] disorders
0.616 0.384 0.000
T90.5 Sequelae of intracranial injury
0.616 0.384 0.000
G25.3 Myoclonus
0.615 0.385 0.000
H60.3 Other infective otitis externa
0.614 0.386 0.000
W55 Bitten or struck by other mammals
0.613 0.387 0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb
0.613 0.387 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.612 0.388 0.000
Y46.2 Hydantoin derivatives
0.612 0.388 0.000
B60 Other protozoal diseases, not elsewhere classified
0.612 0.388 0.000
B58 Toxoplasmosis
0.612 0.388 0.000
B57 Chagas' disease
0.612 0.388 0.000
B56 African trypanosomiasis
0.612 0.388 0.000
B55 Leishmaniasis
0.612 0.388 0.000
B53 Other parasitologically confirmed malaria
0.612 0.388 0.000
B52 Plasmodium malariae malaria
0.612 0.388 0.000
B51 Plasmodium vivax malaria
0.612 0.388 0.000
B64 Unspecified protozoal disease
0.612 0.388 0.000
B54 Unspecified malaria
0.612 0.388 0.000
F38 Other mood [affective] disorders
0.611 0.388 0.000
S00.0 Superficial injury of scalp
0.611 0.389 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.610 0.390 0.000
Chapter XXII Codes for special purposes
0.610 0.390 0.000
T92.1 Sequelae of fracture of arm
0.609 0.391 0.000
S72.3 Fracture of shaft of femur
0.608 0.391 0.000
F06.7 Mild cognitive disorder
0.608 0.392 0.000
T90.8 Sequelae of other specified injuries of head
0.608 0.392 0.000
T06 Other injuries involving multiple body regions, not elsewhere classified
0.608 0.392 0.000
T05 Traumatic amputations involving multiple body regions
0.608 0.392 0.000
T04 Crushing injuries involving multiple body regions
0.608 0.392 0.000
T03 Dislocations, sprains and strains involving multiple body regions
0.608 0.392 0.000
T07 Unspecified multiple injuries
0.608 0.392 0.000
A87 Viral meningitis
0.608 0.392 0.000
Y86 Sequelae of other accidents
0.607 0.393 0.000
H70.1 Chronic mastoiditis
0.607 0.393 0.000
T78.2 Anaphylactic shock, unspecified
0.606 0.393 0.000
H61 Other disorders of external ear
0.605 0.395 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.604 0.396 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.604 0.396 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.604 0.396 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.604 0.396 0.000
S05 Injury of eye and orbit
0.604 0.396 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.604 0.396 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.604 0.396 0.000
B16 Acute hepatitis B
0.604 0.396 0.000
S72.0 Fracture of neck of femur
0.603 0.397 0.000
G70-G73 Diseases of myoneural junction and muscle
0.603 0.397 0.000
T09 Other injuries of spine and trunk, level unspecified
0.603 0.397 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.603 0.397 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.603 0.397 0.000
T12 Fracture of lower limb, level unspecified
0.603 0.397 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.603 0.397 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.603 0.397 0.000
T10 Fracture of upper limb, level unspecified
0.603 0.397 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.603 0.397 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.603 0.397 0.000
T08 Fracture of spine, level unspecified
0.603 0.397 0.000
F30.8 Other manic episodes
0.602 0.398 0.000
F30.1 Mania without psychotic symptoms
0.602 0.398 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.602 0.398 0.000
W87 Exposure to unspecified electric current
0.602 0.398 0.000
X58.9 Unspecified place
0.601 0.399 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.600 0.400 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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