TreeWAS – Variant ID: rs73628692

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	0.999	0.001
Chapter X Diseases of the respiratory system	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
I70-I79 Diseases of arteries, arterioles and capillaries	0.995	0.005
J40-J47 Chronic lower respiratory diseases	0.991	0.009
S50-S59 Injuries to the elbow and forearm	0.990	0.010
J47 Bronchiectasis	0.987	0.013
S52 Fracture of forearm	0.984	0.016
D60-D64 Aplastic and other anaemias	0.978	0.022
S60-S69 Injuries to the wrist and hand	0.967	0.033
D64 Other anaemias	0.962	0.038
S52.5 Fracture of lower end of radius	0.960	0.040
I42 Cardiomyopathy	0.959	0.041
I46 Cardiac arrest	0.953	0.047
D64.9 Anaemia, unspecified	0.951	0.049
I74 Arterial embolism and thrombosis	0.948	0.052
S52.50 Fracture of lower end of radius (closed)	0.944	0.056
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.936	0.064
S52.0 Fracture of upper end of ulna	0.934	0.066
Chapter IV Endocrine, nutritional and metabolic diseases	0.932	0.068
Chapter VI Diseases of the nervous system	0.922	0.078
I51 Complications and ill-defined descriptions of heart disease	0.922	0.078
I05-I09 Chronic rheumatic heart diseases	0.911	0.089
J44 Other chronic obstructive pulmonary disease	0.911	0.089
I72 Other aneurysm	0.909	0.091
D50-D53 Nutritional anaemias	0.905	0.095
D68 Other coagulation defects	0.904	0.096
I95-I99 Other and unspecified disorders of the circulatory system	0.902	0.098
S90-S99 Injuries to the ankle and foot	0.901	0.099
S52.00 Fracture of upper end of ulna (closed)	0.895	0.105
I50 Heart failure	0.886	0.114
G90-G99 Other disorders of the nervous system	0.882	0.118
J00-J06 Acute upper respiratory infections	0.879	0.121
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.877	0.123
I77 Other disorders of arteries and arterioles	0.872	0.128
J95-J99 Other diseases of the respiratory system	0.870	0.130
I46.0 Cardiac arrest with successful resuscitation	0.864	0.136
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.855	0.145
I46.9 Cardiac arrest, unspecified	0.852	0.148
I78 Diseases of capillaries	0.852	0.148
J09-J18 Influenza and pneumonia	0.848	0.152
I42.0 Dilated cardiomyopathy	0.847	0.153
E50-E64 Other nutritional deficiencies	0.843	0.157
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.842	0.158
E10-E14 Diabetes mellitus	0.842	0.158
I42.9 Cardiomyopathy, unspecified	0.840	0.160
I42.8 Other cardiomyopathies	0.839	0.161
G20-G26 Extrapyramidal and movement disorders	0.838	0.162
I37 Pulmonary valve disorders	0.838	0.162
I50.9 Heart failure, unspecified	0.836	0.164
J30-J39 Other diseases of upper respiratory tract	0.832	0.168
I08 Multiple valve diseases	0.832	0.168
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.827	0.173
S66 Injury of muscle and tendon at wrist and hand level	0.825	0.175
D51 Vitamin B12 deficiency anaemia	0.825	0.175
Chapter XX External causes of morbidity and mortality	0.825	0.175
I51.8 Other ill-defined heart diseases	0.823	0.177
T20-T25 Burns and corrosions of external body surface, specified by site	0.821	0.179
S60 Superficial injury of wrist and hand	0.820	0.179
J80-J84 Other respiratory diseases principally affecting the interstitium	0.820	0.180
I51.7 Cardiomegaly	0.818	0.182
Chapter XXII Codes for special purposes	0.815	0.185
I70 Atherosclerosis	0.815	0.185
D62 Acute posthaemorrhagic anaemia	0.812	0.188
J44.8 Other specified chronic obstructive pulmonary disease	0.811	0.189
I60-I69 Cerebrovascular diseases	0.809	0.191
S62 Fracture at wrist and hand level	0.808	0.192
I72.4 Aneurysm of artery of lower extremity	0.807	0.193
J98 Other respiratory disorders	0.803	0.197
T15-T19 Effects of foreign body entering through natural orifice	0.799	0.201
I35 Nonrheumatic aortic valve disorders	0.794	0.206
Chapter I Certain infectious and parasitic diseases	0.792	0.208
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.789	0.211
S52.7 Multiple fractures of forearm	0.788	0.211
I71 Aortic aneurysm and dissection	0.787	0.213
D68.9 Coagulation defect, unspecified	0.785	0.215
I74.5 Embolism and thrombosis of iliac artery	0.785	0.215
I36 Nonrheumatic tricuspid valve disorders	0.783	0.216
I77.0 Arteriovenous fistula, acquired	0.780	0.220
G99 Other disorders of nervous system in diseases classified elsewhere	0.780	0.220
E53 Deficiency of other B group vitamins	0.779	0.221
S50 Superficial injury of forearm	0.777	0.223
S52.2 Fracture of shaft of ulna	0.771	0.229
S68 Traumatic amputation of wrist and hand	0.770	0.230
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.769	0.231
J42 Unspecified chronic bronchitis	0.766	0.234
I95 Hypotension	0.766	0.234
I38 Endocarditis, valve unspecified	0.762	0.238
G50-G59 Nerve, nerve root and plexus disorders	0.762	0.238
S10-S19 Injuries to the neck	0.762	0.238
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.762	0.238
I08.0 Disorders of both mitral and aortic valves	0.761	0.238
J04 Acute laryngitis and tracheitis	0.758	0.242
G90 Disorders of autonomic nervous system	0.758	0.242
E00-E07 Disorders of thyroid gland	0.757	0.243
J39 Other diseases of upper respiratory tract	0.755	0.245
I27 Other pulmonary heart diseases	0.755	0.245
S20-S29 Injuries to the thorax	0.751	0.249
D50 Iron deficiency anaemia	0.751	0.249
S91 Open wound of ankle and foot	0.750	0.250
E14 Unspecified diabetes mellitus	0.749	0.251
S60.9 Superficial injury of wrist and hand, unspecified	0.747	0.253
S65 Injury of blood vessels at wrist and hand level	0.745	0.255
I62 Other nontraumatic intracranial haemorrhage	0.743	0.257
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.743	0.257
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.741	0.259
J17 Pneumonia in diseases classified elsewhere	0.741	0.259
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.739	0.261
J46 Status asthmaticus	0.739	0.261
B35-B49 Mycoses	0.738	0.262
I69 Sequelae of cerebrovascular disease	0.737	0.263
I34 Nonrheumatic mitral valve disorders	0.736	0.263
S64 Injury of nerves at wrist and hand level	0.736	0.264
I72.3 Aneurysm of iliac artery	0.735	0.264
S67 Crushing injury of wrist and hand	0.735	0.265
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.734	0.266
E53.8 Deficiency of other specified B group vitamins	0.734	0.266
Chapter VIII Diseases of the ear and mastoid process	0.733	0.267
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.729	0.270
J01 Acute sinusitis	0.728	0.272
I98 Other disorders of circulatory system in diseases classified elsewhere	0.727	0.273
S96 Injury of muscle and tendon at ankle and foot level	0.727	0.273
S99 Other and unspecified injuries of ankle and foot	0.725	0.274
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.723	0.277
I37.1 Pulmonary valve insufficiency	0.722	0.278
D61 Other aplastic anaemias	0.720	0.280
I31 Other diseases of pericardium	0.720	0.280
G93 Other disorders of brain	0.720	0.280
G24 Dystonia	0.719	0.281
J80 Adult respiratory distress syndrome	0.717	0.283
S61 Open wound of wrist and hand	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284
I48 Atrial fibrillation and flutter	0.716	0.284
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.284
I41 Myocarditis in diseases classified elsewhere	0.716	0.284
I40 Acute myocarditis	0.716	0.284
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284
I32 Pericarditis in diseases classified elsewhere	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
J35 Chronic diseases of tonsils and adenoids	0.716	0.284
G20 Parkinson's disease	0.715	0.285
D68.2 Hereditary deficiency of other clotting factors	0.714	0.286
I77.6 Arteritis, unspecified	0.714	0.286
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.713	0.287
G57 Mononeuropathies of lower limb	0.713	0.287
I42.6 Alcoholic cardiomyopathy	0.713	0.287
I95.9 Hypotension, unspecified	0.711	0.289
J41 Simple and mucopurulent chronic bronchitis	0.710	0.290
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.710	0.290
S59 Other and unspecified injuries of forearm	0.709	0.290
S58 Traumatic amputation of forearm	0.709	0.290
S57 Crushing injury of forearm	0.709	0.290
S56 Injury of muscle and tendon at forearm level	0.709	0.290
S55 Injury of blood vessels at forearm level	0.709	0.290
S54 Injury of nerves at forearm level	0.709	0.290
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.709	0.290
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.709	0.291
I45 Other conduction disorders	0.708	0.292
I09 Other rheumatic heart diseases	0.706	0.294
S52.9 Fracture of forearm, part unspecified	0.705	0.295
S52.4 Fracture of shafts of both ulna and radius	0.705	0.295
S52.3 Fracture of shaft of radius	0.705	0.295
I78.1 Naevus, nonneoplastic	0.703	0.297
I05 Rheumatic mitral valve diseases	0.701	0.299
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.701	0.299
Y60-Y69 Misadventures to patients during surgical and medical care	0.701	0.299
S52.8 Fracture of other parts of forearm	0.700	0.300
W50-W64 Exposure to animate mechanical forces	0.699	0.301
B37 Candidiasis	0.699	0.301
E04 Other non-toxic goitre	0.699	0.301
I51.0 Cardiac septal defect, acquired	0.696	0.304
E10 Insulin-dependent diabetes mellitus	0.696	0.304
T23 Burn and corrosion of wrist and hand	0.694	0.306
D55-D59 Haemolytic anaemias	0.694	0.306
I33 Acute and subacute endocarditis	0.694	0.306
G99.2 Myelopathy in diseases classified elsewhere	0.692	0.308
S90 Superficial injury of ankle and foot	0.692	0.308
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.692	0.308
D64.8 Other specified anaemias	0.690	0.310
D64.4 Congenital dyserythropoietic anaemia	0.690	0.310
D64.3 Other sideroblastic anaemias	0.690	0.310
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.690	0.310
D64.1 Secondary sideroblastic anaemia due to disease	0.690	0.310
D64.0 Hereditary sideroblastic anaemia	0.690	0.310
G94 Other disorders of brain in diseases classified elsewhere	0.690	0.310
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.689	0.311
J13 Pneumonia due to Streptococcus pneumoniae	0.689	0.311
S52.51 Fracture of lower end of radius (open)	0.688	0.311
S52.01 Fracture of upper end of ulna (open)	0.688	0.312
G35-G37 Demyelinating diseases of the central nervous system	0.688	0.312
I42.7 Cardiomyopathy due to drugs and other external agents	0.687	0.313
I42.5 Other restrictive cardiomyopathy	0.687	0.313
I42.4 Endocardial fibroelastosis	0.687	0.313
I42.3 Endomyocardial (eosinophilic) disease	0.687	0.313
I35.1 Aortic (valve) insufficiency	0.687	0.313
I70.2 Atherosclerosis of arteries of the extremities	0.686	0.314
I42.2 Other hypertrophic cardiomyopathy	0.684	0.316
I50.0 Congestive heart failure	0.684	0.316
S69 Other and unspecified injuries of wrist and hand	0.684	0.316
I46.1 Sudden cardiac death, so described	0.683	0.317
S40-S49 Injuries to the shoulder and upper arm	0.682	0.318
I51.4 Myocarditis, unspecified	0.682	0.318
I74.9 Embolism and thrombosis of unspecified artery	0.680	0.320
I74.8 Embolism and thrombosis of other arteries	0.680	0.320
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.680	0.320
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.680	0.320
I74.0 Embolism and thrombosis of abdominal aorta	0.680	0.320
J20-J22 Other acute lower respiratory infections	0.679	0.321
J39.2 Other diseases of pharynx	0.679	0.321
I35.9 Aortic valve disorder, unspecified	0.678	0.322
I72.8 Aneurysm of other specified arteries	0.677	0.323
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.677	0.323
I08.1 Disorders of both mitral and tricuspid valves	0.676	0.324
T79-T79 Certain early complications of trauma	0.676	0.324
T36-T50 Poisoning by drugs, medicaments and biological substances	0.674	0.326
G56 Mononeuropathies of upper limb	0.672	0.328
I30 Acute pericarditis	0.672	0.328
I78.8 Other diseases of capillaries	0.671	0.329
D67 Hereditary factor IX deficiency	0.671	0.329
D66 Hereditary factor VIII deficiency	0.671	0.329
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.671	0.329
J15 Bacterial pneumonia, not elsewhere classified	0.669	0.331
G90.9 Disorder of autonomic nervous system, unspecified	0.669	0.331
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.668	0.331
J06 Acute upper respiratory infections of multiple and unspecified sites	0.668	0.332
G70-G73 Diseases of myoneural junction and muscle	0.668	0.332
G95 Other diseases of spinal cord	0.666	0.334
J34 Other disorders of nose and nasal sinuses	0.665	0.335
E04.9 Non-toxic goitre, unspecified	0.664	0.336
J02 Acute pharyngitis	0.663	0.337
I44 Atrioventricular and left bundle-branch block	0.662	0.338
I77.9 Disorder of arteries and arterioles, unspecified	0.662	0.338
W20-W49 Exposure to inanimate mechanical forces	0.662	0.338
I51.6 Cardiovascular disease, unspecified	0.661	0.339
I51.5 Myocardial degeneration	0.661	0.339
I51.3 Intracardiac thrombosis, not elsewhere classified	0.661	0.339
I51.2 Rupture of papillary muscle, not elsewhere classified	0.661	0.339
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.661	0.339
S62.5 Fracture of thumb	0.661	0.339
I08.2 Disorders of both aortic and tricuspid valves	0.660	0.340
G93.3 Postviral fatigue syndrome	0.660	0.340
D68.8 Other specified coagulation defects	0.660	0.340
D50.9 Iron deficiency anaemia, unspecified	0.659	0.341
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.657	0.343
X60-X84 Intentional self-harm	0.656	0.344
E06 Thyroiditis	0.655	0.345
G57.6 Lesion of plantar nerve	0.655	0.345
J98.8 Other specified respiratory disorders	0.654	0.346
B20-B24 Human immunodeficiency virus [HIV] disease	0.654	0.346
I06 Rheumatic aortic valve diseases	0.653	0.346
I72.9 Aneurysm of unspecified site	0.652	0.348
I72.6 Aneurysm and dissection of vertebral artery	0.652	0.348
I72.5 Aneurysm and dissection of other precerebral arteries	0.652	0.348
I72.2 Aneurysm of renal artery	0.652	0.348
I72.1 Aneurysm of artery of upper extremity	0.652	0.348
I72.0 Aneurysm of carotid artery	0.652	0.348
B37.0 Candidal stomatitis	0.650	0.350
E55 Vitamin D deficiency	0.650	0.350
G96 Other disorders of central nervous system	0.649	0.351
E40-E46 Malnutrition	0.649	0.351
D53 Other nutritional anaemias	0.648	0.351
S52.70 Multiple fractures of forearm (closed)	0.649	0.351
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.648	0.352
D68.6 Other Thrombophilia	0.648	0.352
D68.5 Primary Thrombophilia	0.648	0.352
D68.4 Acquired coagulation factor deficiency	0.648	0.352
D68.1 Hereditary factor XI deficiency	0.648	0.352
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.648	0.352
S61.1 Open wound of finger(s) with damage to nail	0.646	0.354
J99 Respiratory disorders in diseases classified elsewhere	0.646	0.354
S98 Traumatic amputation of ankle and foot	0.646	0.354
S97 Crushing injury of ankle and foot	0.646	0.354
S95 Injury of blood vessels at ankle and foot level	0.646	0.354
S94 Injury of nerves at ankle and foot level	0.646	0.354
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.646	0.354
E14.3 With ophthalmic complications	0.645	0.355
D80-D89 Certain disorders involving the immune mechanism	0.643	0.357
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.642	0.358
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.641	0.359
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.641	0.359
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.641	0.359
I27.0 Primary pulmonary hypertension	0.639	0.361
B15-B19 Viral hepatitis	0.639	0.361
J98.9 Respiratory disorder, unspecified	0.637	0.363
I69.3 Sequelae of cerebral infarction	0.637	0.363
J04.1 Acute tracheitis	0.637	0.363
J98.4 Other disorders of lung	0.636	0.364
J98.6 Disorders of diaphragm	0.636	0.364
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.636	0.364
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.635	0.365
J98.5 Diseases of mediastinum, not elsewhere classified	0.634	0.365
T18 Foreign body in alimentary tract	0.634	0.366
G24.9 Dystonia, unspecified	0.634	0.366
T66-T78 Other and unspecified effects of external causes	0.633	0.367
G98 Other disorders of nervous system, not elsewhere classified	0.632	0.368
G92 Toxic encephalopathy	0.632	0.368
I99 Other and unspecified disorders of circulatory system	0.632	0.368
I78.0 Hereditary haemorrhagic telangiectasia	0.631	0.369
Q20-Q28 Congenital malformations of the circulatory system	0.631	0.369
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.630	0.370
S80-S89 Injuries to the knee and lower leg	0.630	0.370
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.629	0.371
I27.8 Other specified pulmonary heart diseases	0.628	0.372
S62.7 Multiple fractures of fingers	0.627	0.372
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.626	0.374
I77.5 Necrosis of artery	0.625	0.374
I77.4 Coeliac artery compression syndrome	0.625	0.374
I77.3 Arterial fibromuscular dysplasia	0.625	0.374
I77.2 Rupture of artery	0.625	0.374
I69.0 Sequelae of subarachnoid haemorrhage	0.625	0.375
T85 Complications of other internal prosthetic devices, implants and grafts	0.625	0.375
S50.9 Superficial injury of forearm, unspecified	0.625	0.375
J96 Respiratory failure, not elsewhere classified	0.623	0.376
G56.0 Carpal tunnel syndrome	0.623	0.377
Y52 Agents primarily affecting the cardiovascular system	0.622	0.378
S52.20 Fracture of shaft of ulna (closed)	0.618	0.382
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.617	0.383
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.616	0.384
E14.9 Without complications	0.614	0.386
A50-A64 Infections with a predominantly sexual mode of transmission	0.614	0.386
S52.1 Fracture of upper end of radius	0.614	0.386
H60-H62 Diseases of external ear	0.612	0.388
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.612	0.388
D68.0 Von Willebrand's disease	0.612	0.388
G52 Disorders of other cranial nerves	0.612	0.388
I78.9 Disease of capillaries, unspecified	0.611	0.389
E65-E68 Obesity and other hyperalimentation	0.611	0.389
I60 Subarachnoid haemorrhage	0.611	0.389
S62.0 Fracture of navicular [scaphoid] bone of hand	0.609	0.390
S52.6 Fracture of lower end of both ulna and radius	0.609	0.391
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.608	0.392
J12 Viral pneumonia, not elsewhere classified	0.608	0.392
J09 Influenza due to certain identified influenza virus	0.608	0.392
B50-B64 Protozoal diseases	0.607	0.393
S91.0 Open wound of ankle	0.607	0.393
J01.0 Acute maxillary sinusitis	0.606	0.394
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.605	0.395
J04.0 Acute laryngitis	0.605	0.395
S68.0 Traumatic amputation of thumb (complete)(partial)	0.605	0.395
E64 Sequelae of malnutrition and other nutritional deficiencies	0.604	0.396
E63 Other nutritional deficiencies	0.604	0.396
E56 Other vitamin deficiencies	0.604	0.396
E51 Thiamine deficiency	0.604	0.396
E50 Vitamin A deficiency	0.604	0.396
E60 Dietary zinc deficiency	0.604	0.396
E59 Dietary selenium deficiency	0.604	0.396
E58 Dietary calcium deficiency	0.604	0.396
E54 Ascorbic acid deficiency	0.604	0.396
E52 Niacin deficiency [pellagra]	0.604	0.396
T14 Injury of unspecified body region	0.604	0.396
E16 Other disorders of pancreatic internal secretion	0.604	0.396
G80-G83 Cerebral palsy and other paralytic syndromes	0.604	0.396
E70-E90 Metabolic disorders	0.604	0.396
G25 Other extrapyramidal and movement disorders	0.604	0.396
E12 Malnutrition-related diabetes mellitus	0.603	0.396
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.602	0.398
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.602	0.398
J00 Acute nasopharyngitis [common cold]	0.602	0.398
J39.8 Other specified diseases of upper respiratory tract	0.602	0.398
T17 Foreign body in respiratory tract	0.602	0.398
E11 Non-insulin-dependent diabetes mellitus	0.602	0.398
T59 Toxic effect of other gases, fumes and vapours	0.601	0.399
G30-G32 Other degenerative diseases of the nervous system	0.601	0.399
I98.2 Oesophageal varices in diseases classified elsewhere	0.601	0.399
G23 Other degenerative diseases of basal ganglia	0.601	0.399
G21 Secondary Parkinsonism	0.601	0.399
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.601	0.399
G22 Parkinsonism in diseases classified elsewhere	0.601	0.399
I37.9 Pulmonary valve disorder, unspecified	0.600	0.399
I37.8 Other pulmonary valve disorders	0.600	0.399
I37.2 Pulmonary valve stenosis with insufficiency	0.600	0.399
I37.0 Pulmonary valve stenosis	0.600	0.399
S99.9 Unspecified injury of ankle and foot	0.600	0.400
S22 Fracture of rib(s), sternum and thoracic spine	0.599	0.401
G57.8 Other mononeuropathies of lower limb	0.597	0.403
G00-G09 Inflammatory diseases of the central nervous system	0.597	0.403
Q50-Q56 Congenital malformations of genital organs	0.597	0.403
B65-B83 Helminthiases	0.597	0.403
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.597	0.403
I08.9 Multiple valve disease, unspecified	0.596	0.404
I08.8 Other multiple valve diseases	0.596	0.404
S62.2 Fracture of first metacarpal bone	0.595	0.405
J84 Other interstitial pulmonary diseases	0.595	0.405
I71.0 Dissection of aorta [any part]	0.595	0.405
I07 Rheumatic tricuspid valve diseases	0.595	0.405
X20-X29 Contact with venomous animals and plants	0.595	0.405
S92 Fracture of foot, except ankle	0.594	0.406
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.593	0.407
Q38-Q45 Other congenital malformations of the digestive system	0.593	0.407
I28 Other diseases of pulmonary vessels	0.593	0.407
S12 Fracture of neck	0.593	0.407
S27 Injury of other and unspecified intrathoracic organs	0.593	0.407
S62.4 Multiple fractures of metacarpal bones	0.592	0.408
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.592	0.408
S51 Open wound of forearm	0.592	0.408
S66.8 Injury of other muscles and tendons at wrist and hand level	0.592	0.408
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.592	0.408
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.592	0.408
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.592	0.408
D51.8 Other vitamin B12 deficiency anaemias	0.592	0.408
D51.3 Other dietary vitamin B12 deficiency anaemia	0.592	0.408
D51.2 Transcobalamin II deficiency	0.592	0.408
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.592	0.408
Y35-Y36 Legal intervention and operations of war	0.592	0.408
Y10-Y34 Event of undetermined intent	0.592	0.408
Y00-Y09 Assault	0.592	0.408
X85-X99 Assault	0.592	0.408
X58-X59 Accidental exposure to other and unspecified factors	0.592	0.408
X50-X57 Overexertion, travel and privation	0.592	0.408
X30-X39 Exposure to forces of nature	0.592	0.408
X10-X19 Contact with heat and hot substances	0.592	0.408
X00-X09 Exposure to smoke, fire and flames	0.592	0.408
W75-W84 Other accidental threats to breathing	0.592	0.408
W65-W74 Accidental drowning and submersion	0.592	0.408
V98-V99 Other and unspecified transport accidents	0.592	0.408
V95-V97 Air and space transport accidents	0.592	0.408
V90-V94 Water transport accidents	0.592	0.408
V70-V79 Bus occupant injured in transport accident	0.592	0.408
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.592	0.408
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.592	0.408
V40-V49 Car occupant injured in transport accident	0.592	0.408
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.592	0.408
V01-V09 Pedestrian injured in transport accident	0.592	0.408
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.590	0.410
J98.0 Diseases of bronchus, not elsewhere classified	0.590	0.410
S91.3 Open wound of other parts of foot	0.589	0.411
T25 Burn and corrosion of ankle and foot	0.589	0.411
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.589	0.411
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.589	0.411
T21 Burn and corrosion of trunk	0.589	0.411
T20 Burn and corrosion of head and neck	0.589	0.411
S60.7 Multiple superficial injuries of wrist and hand	0.588	0.412
S60.2 Contusion of other parts of wrist and hand	0.588	0.412
S60.1 Contusion of finger(s) with damage to nail	0.588	0.412
S60.0 Contusion of finger(s) without damage to nail	0.588	0.412
J14 Pneumonia due to Haemophilus influenzae	0.588	0.412
J17.3 Pneumonia in parasitic diseases	0.588	0.412
J82 Pulmonary eosinophilia, not elsewhere classified	0.588	0.412
S65.5 Injury of blood vessel(s) of other finger	0.586	0.414
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.586	0.414
I70.9 Generalised and unspecified atherosclerosis	0.584	0.416
I70.8 Atherosclerosis of other arteries	0.584	0.416
I70.1 Atherosclerosis of renal artery	0.584	0.416
I70.0 Atherosclerosis of aorta	0.584	0.416
S62.6 Fracture of other finger	0.584	0.416
J37 Chronic laryngitis and laryngotracheitis	0.584	0.416
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.584	0.416
T23.0 Burn of unspecified degree of wrist and hand	0.584	0.416
J10 Influenza due to identified influenza virus	0.583	0.417
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.583	0.417
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.582	0.418
B37.3 Candidiasis of vulva and vagina	0.582	0.418
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.582	0.418
I64 Stroke, not specified as haemorrhage or infarction	0.581	0.419
V80-V89 Other land transport accidents	0.581	0.419
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.580	0.420
I68 Cerebrovascular disorders in diseases classified elsewhere	0.580	0.420
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.580	0.420
D69 Purpura and other haemorrhagic conditions	0.579	0.421
S62.1 Fracture of other carpal bone(s)	0.579	0.421
J11 Influenza, virus not identified	0.577	0.423
I61 Intracerebral haemorrhage	0.577	0.423
H65-H75 Diseases of middle ear and mastoid	0.576	0.423
J35.8 Other chronic diseases of tonsils and adenoids	0.576	0.424
J98.3 Compensatory emphysema	0.576	0.424
J98.2 Interstitial emphysema	0.576	0.424
Y44 Agents primarily affecting blood constituents	0.574	0.426
I95.8 Other hypotension	0.573	0.426
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.573	0.426
I27.9 Pulmonary heart disease, unspecified	0.573	0.427
T19 Foreign body in genito-urinary tract	0.573	0.427
T15 Foreign body on external eye	0.573	0.427
T16 Foreign body in ear	0.573	0.427
X40-X49 Accidental poisoning by and exposure to noxious substances	0.572	0.428
S64.0 Injury of ulnar nerve at wrist and hand level	0.572	0.428
I77.8 Other specified disorders of arteries and arterioles	0.572	0.428
E13 Other specified diabetes mellitus	0.570	0.430
I44.7 Left bundle-branch block, unspecified	0.570	0.430
Q80-Q89 Other congenital malformations	0.569	0.430
I97.1 Other functional disturbances following cardiac surgery	0.569	0.431
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.569	0.431
I27.2 Other secondary pulmonary hypertension	0.569	0.431
S67.0 Crushing injury of thumb and other finger(s)	0.569	0.431
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.568	0.431
B85-B89 Pediculosis, acariasis and other infestations	0.568	0.432
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.568	0.432
A75-A79 Rickettsioses	0.568	0.432
A70-A74 Other diseases caused by chlamydiae	0.568	0.432
A65-A69 Other spirochaetal diseases	0.568	0.432
A20-A28 Certain zoonotic bacterial diseases	0.568	0.432
A15-A19 Tuberculosis	0.568	0.432
Q35-Q37 Cleft lip and cleft palate	0.566	0.434
Q30-Q34 Congenital malformations of the respiratory system	0.566	0.434

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations