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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74048198
log Bayes Factor = 5.94724
Chromosome 11   position 2,118,282  (GRCh37) Explore rs74048198 on Ensembl!
Variant rs74048198 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I60 Subarachnoid haemorrhage
0.995 0.005 0.000
# Top node
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
I10-I15 Hypertensive diseases
0.991 0.009 0.000
E20-E35 Disorders of other endocrine glands
0.991 0.009 0.000
I10 Essential (primary) hypertension
0.984 0.016 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.972 0.028 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.969 0.031 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.960 0.040 0.000
Chapter XX External causes of morbidity and mortality
0.954 0.046 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.953 0.047 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.948 0.052 0.000
O16 Unspecified maternal hypertension
0.942 0.058 0.000
I69 Sequelae of cerebrovascular disease
0.931 0.069 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.926 0.074 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.924 0.076 0.000
I51 Complications and ill-defined descriptions of heart disease
0.921 0.079 0.000
W00-W19 Falls
0.917 0.083 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.916 0.084 0.000
E28 Ovarian dysfunction
0.913 0.087 0.000
Chapter XXII Codes for special purposes
0.906 0.094 0.000
I34 Nonrheumatic mitral valve disorders
0.905 0.095 0.000
E22 Hyperfunction of pituitary gland
0.902 0.098 0.000
I46 Cardiac arrest
0.900 0.100 0.000
E70-E90 Metabolic disorders
0.896 0.104 0.000
I35 Nonrheumatic aortic valve disorders
0.889 0.111 0.000
I86 Varicose veins of other sites
0.888 0.112 0.000
I82 Other venous embolism and thrombosis
0.883 0.117 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.882 0.118 0.000
I83 Varicose veins of lower extremities
0.877 0.123 0.000
Chapter VI Diseases of the nervous system
0.875 0.125 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.874 0.126 0.000
I30 Acute pericarditis
0.874 0.126 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.873 0.127 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.873 0.127 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.868 0.132 0.000
D80-D89 Certain disorders involving the immune mechanism
0.868 0.132 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.862 0.138 0.000
E21.0 Primary hyperparathyroidism
0.858 0.142 0.000
I45 Other conduction disorders
0.858 0.142 0.000
W10 Fall on and from stairs and steps
0.852 0.148 0.000
M20-M25 Other joint disorders
0.850 0.150 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.850 0.150 0.000
E34 Other endocrine disorders
0.849 0.151 0.000
O85-O92 Complications predominantly related to the puerperium
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
M35 Other systemic involvement of connective tissue
0.844 0.156 0.000
I34.0 Mitral (valve) insufficiency
0.841 0.159 0.000
M35.3 Polymyalgia rheumatica
0.841 0.159 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.841 0.159 0.000
D50-D53 Nutritional anaemias
0.838 0.162 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.835 0.165 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.835 0.165 0.000
I49 Other cardiac arrhythmias
0.835 0.165 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.832 0.167 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.832 0.168 0.000
I05-I09 Chronic rheumatic heart diseases
0.827 0.173 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.823 0.177 0.000
M05-M14 Inflammatory polyarthropathies
0.818 0.182 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.813 0.187 0.000
I87 Other disorders of veins
0.812 0.188 0.000
W10.8 Other specified place
0.812 0.188 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.811 0.189 0.000
Chapter I Certain infectious and parasitic diseases
0.807 0.193 0.000
I86.8 Varicose veins of other specified sites
0.807 0.193 0.000
E28.2 Polycystic ovarian syndrome
0.800 0.200 0.000
I46.9 Cardiac arrest, unspecified
0.799 0.201 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.799 0.201 0.000
E23 Hypofunction and other disorders of pituitary gland
0.796 0.203 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.796 0.204 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.794 0.206 0.000
U80 Agent resistant to penicillin and related antibiotics
0.793 0.207 0.000
I45.6 Preexcitation syndrome
0.792 0.208 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.792 0.208 0.000
Chapter V Mental and behavioural disorders
0.792 0.208 0.000
W19 Unspecified fall
0.791 0.209 0.000
V20-V29 Motorcycle rider injured in transport accident
0.790 0.210 0.000
E24 Cushing's syndrome
0.790 0.210 0.000
M13 Other arthritis
0.789 0.211 0.000
I51.7 Cardiomegaly
0.788 0.212 0.000
E27 Other disorders of adrenal gland
0.788 0.212 0.000
I67 Other cerebrovascular diseases
0.786 0.214 0.000
E28.3 Primary ovarian failure
0.785 0.215 0.000
I60.8 Other subarachnoid haemorrhage
0.783 0.217 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.782 0.218 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.778 0.222 0.000
E87.2 Acidosis
0.777 0.223 0.000
D50 Iron deficiency anaemia
0.775 0.225 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.774 0.226 0.000
I82.8 Embolism and thrombosis of other specified veins
0.772 0.228 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.771 0.229 0.000
D70 Agranulocytosis
0.771 0.229 0.000
I47 Paroxysmal tachycardia
0.767 0.233 0.000
E88 Other metabolic disorders
0.767 0.233 0.000
D86 Sarcoidosis
0.758 0.242 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.757 0.243 0.000
E21.3 Hyperparathyroidism, unspecified
0.757 0.243 0.000
V40-V49 Car occupant injured in transport accident
0.756 0.244 0.000
I30.1 Infective pericarditis
0.755 0.245 0.000
U80.1 Methicillin resistant agent
0.754 0.246 0.000
I27 Other pulmonary heart diseases
0.754 0.246 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.754 0.246 0.000
I72 Other aneurysm
0.754 0.246 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.753 0.247 0.000
M13.9 Arthritis, unspecified
0.753 0.247 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.752 0.248 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.752 0.248 0.000
I12 Hypertensive renal disease
0.752 0.248 0.000
M10 Gout
0.748 0.252 0.000
I51.9 Heart disease, unspecified
0.748 0.252 0.000
Y83.6 Removal of other organ (partial) (total)
0.747 0.253 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.745 0.255 0.000
E87.0 Hyperosmolality and hypernatraemia
0.743 0.257 0.000
G70-G73 Diseases of myoneural junction and muscle
0.740 0.260 0.000
I35.0 Aortic (valve) stenosis
0.740 0.260 0.000
B35-B49 Mycoses
0.739 0.261 0.000
I74 Arterial embolism and thrombosis
0.739 0.261 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.734 0.266 0.000
G90-G99 Other disorders of the nervous system
0.733 0.267 0.000
W19.9 Unspecified place
0.733 0.267 0.000
Y43 Primarily systemic agents
0.731 0.269 0.000
D50.9 Iron deficiency anaemia, unspecified
0.731 0.269 0.000
E20 Hypoparathyroidism
0.731 0.269 0.000
I37 Pulmonary valve disorders
0.731 0.269 0.000
I11 Hypertensive heart disease
0.730 0.270 0.000
W06 Fall involving bed
0.729 0.271 0.000
I69.3 Sequelae of cerebral infarction
0.729 0.271 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.729 0.271 0.000
Y84.0 Cardiac catheterisation
0.728 0.272 0.000
I44 Atrioventricular and left bundle-branch block
0.727 0.273 0.000
E50-E64 Other nutritional deficiencies
0.727 0.273 0.000
X60-X84 Intentional self-harm
0.726 0.274 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.726 0.274 0.000
A00-A09 Intestinal infectious diseases
0.725 0.275 0.000
I81 Portal vein thrombosis
0.725 0.275 0.000
I46.0 Cardiac arrest with successful resuscitation
0.723 0.277 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.721 0.279 0.000
I80 Phlebitis and thrombophlebitis
0.719 0.281 0.000
I49.9 Cardiac arrhythmia, unspecified
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I05 Rheumatic mitral valve diseases
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.283 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.713 0.287 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.713 0.287 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.713 0.287 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.713 0.287 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
G30-G32 Other degenerative diseases of the nervous system
0.713 0.287 0.000
I20-I25 Ischaemic heart diseases
0.713 0.287 0.000
I82.2 Embolism and thrombosis of vena cava
0.712 0.288 0.000
I13 Hypertensive heart and renal disease
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.710 0.290 0.000
E32 Diseases of thymus
0.710 0.290 0.000
E31 Polyglandular dysfunction
0.710 0.290 0.000
E30 Disorders of puberty, not elsewhere classified
0.710 0.290 0.000
E25 Adrenogenital disorders
0.710 0.290 0.000
Y83.9 Surgical procedure, unspecified
0.709 0.291 0.000
I38 Endocarditis, valve unspecified
0.709 0.291 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.708 0.292 0.000
Y83.4 Other reconstructive surgery
0.706 0.294 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.704 0.296 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.702 0.298 0.000
E87.5 Hyperkalaemia
0.702 0.298 0.000
I85 Oesophageal varices
0.702 0.298 0.000
I61 Intracerebral haemorrhage
0.701 0.299 0.000
I72.4 Aneurysm of artery of lower extremity
0.701 0.299 0.000
I24 Other acute ischaemic heart diseases
0.700 0.300 0.000
E34.0 Carcinoid syndrome
0.700 0.300 0.000
D86.0 Sarcoidosis of lung
0.700 0.300 0.000
M10.9 Gout, unspecified
0.697 0.303 0.000
E65-E68 Obesity and other hyperalimentation
0.697 0.303 0.000
I45.5 Other specified heart block
0.697 0.303 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.697 0.303 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.696 0.304 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.695 0.305 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
I49.8 Other specified cardiac arrhythmias
0.691 0.309 0.000
I86.1 Scrotal varices
0.690 0.310 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.689 0.311 0.000
I30.9 Acute pericarditis, unspecified
0.688 0.312 0.000
O15 Eclampsia
0.688 0.312 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.688 0.312 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.688 0.312 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
Q80-Q89 Other congenital malformations
0.687 0.313 0.000
E26 Hyperaldosteronism
0.686 0.314 0.000
O90 Complications of the puerperium, not elsewhere classified
0.686 0.314 0.000
E34.9 Endocrine disorder, unspecified
0.684 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.684 0.316 0.000
Y10-Y34 Event of undetermined intent
0.684 0.316 0.000
Y00-Y09 Assault
0.684 0.316 0.000
X85-X99 Assault
0.684 0.316 0.000
X30-X39 Exposure to forces of nature
0.684 0.316 0.000
X10-X19 Contact with heat and hot substances
0.684 0.316 0.000
X00-X09 Exposure to smoke, fire and flames
0.684 0.316 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.684 0.316 0.000
W75-W84 Other accidental threats to breathing
0.684 0.316 0.000
W65-W74 Accidental drowning and submersion
0.684 0.316 0.000
V98-V99 Other and unspecified transport accidents
0.684 0.316 0.000
V95-V97 Air and space transport accidents
0.684 0.316 0.000
V90-V94 Water transport accidents
0.684 0.316 0.000
V70-V79 Bus occupant injured in transport accident
0.684 0.316 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.684 0.316 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.684 0.316 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.684 0.316 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.684 0.316 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.682 0.318 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.682 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.681 0.319 0.000
F99-F99 Unspecified mental disorder
0.679 0.321 0.000
M35.8 Other specified systemic involvement of connective tissue
0.678 0.322 0.000
E40-E46 Malnutrition
0.677 0.323 0.000
W08 Fall involving other furniture
0.677 0.323 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.677 0.323 0.000
W50-W64 Exposure to animate mechanical forces
0.676 0.323 0.000
M34 Systemic sclerosis
0.676 0.324 0.000
M25 Other joint disorders, not elsewhere classified
0.676 0.324 0.000
E10-E14 Diabetes mellitus
0.676 0.324 0.000
X20-X29 Contact with venomous animals and plants
0.675 0.325 0.000
I44.7 Left bundle-branch block, unspecified
0.675 0.325 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.674 0.326 0.000
O40 Polyhydramnios
0.673 0.327 0.000
M60-M63 Disorders of muscles
0.673 0.327 0.000
D80 Immunodeficiency with predominantly antibody defects
0.673 0.327 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.673 0.327 0.000
B44 Aspergillosis
0.673 0.327 0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.672 0.328 0.000
I15 Secondary hypertension
0.671 0.328 0.000
I67.1 Cerebral aneurysm, nonruptured
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.669 0.331 0.000
E22.0 Acromegaly and pituitary gigantism
0.669 0.331 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.669 0.331 0.000
I88 Nonspecific lymphadenitis
0.668 0.332 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.667 0.333 0.000
I45.9 Conduction disorder, unspecified
0.666 0.334 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.664 0.336 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.664 0.336 0.000
E21.4 Other specified disorders of parathyroid gland
0.664 0.336 0.000
E21.2 Other hyperparathyroidism
0.664 0.336 0.000
I86.4 Gastric varices
0.663 0.337 0.000
W18 Other fall on same level
0.663 0.337 0.000
Y58 Bacterial vaccines
0.662 0.338 0.000
Y52 Agents primarily affecting the cardiovascular system
0.661 0.339 0.000
I51.5 Myocardial degeneration
0.660 0.340 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.660 0.340 0.000
I09 Other rheumatic heart diseases
0.659 0.341 0.000
E89.0 Postprocedural hypothyroidism
0.659 0.341 0.000
I51.4 Myocarditis, unspecified
0.658 0.341 0.000
Y43.3 Other antineoplastic drugs
0.658 0.342 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.657 0.343 0.000
W15 Fall from cliff
0.657 0.343 0.000
W14 Fall from tree
0.657 0.343 0.000
W12 Fall on and from scaffolding
0.657 0.343 0.000
W11 Fall on and from ladder
0.657 0.343 0.000
W09 Fall involving playground equipment
0.657 0.343 0.000
W05 Fall involving wheelchair
0.657 0.343 0.000
W04 Fall while being carried or supported by other persons
0.657 0.343 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.657 0.343 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.657 0.343 0.000
W00 Fall on same level involving ice and snow
0.657 0.343 0.000
I49.1 Atrial premature depolarisation
0.657 0.343 0.000
O43 Placental disorders
0.656 0.344 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.655 0.345 0.000
G91 Hydrocephalus
0.655 0.345 0.000
E28.9 Ovarian dysfunction, unspecified
0.654 0.345 0.000
E28.8 Other ovarian dysfunction
0.654 0.345 0.000
E28.1 Androgen excess
0.654 0.345 0.000
E28.0 Oestrogen excess
0.654 0.345 0.000
I24.8 Other forms of acute ischaemic heart disease
0.652 0.348 0.000
B15-B19 Viral hepatitis
0.652 0.348 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.650 0.350 0.000
W17 Other fall from one level to another
0.650 0.350 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.650 0.350 0.000
E22.1 Hyperprolactinaemia
0.649 0.350 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.649 0.351 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.649 0.351 0.000
G83 Other paralytic syndromes
0.648 0.352 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.648 0.352 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.647 0.353 0.000
E22.8 Other hyperfunction of pituitary gland
0.647 0.353 0.000
O12.0 Gestational oedema
0.646 0.354 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.646 0.354 0.000
E24.9 Cushing's syndrome, unspecified
0.646 0.354 0.000
I46.1 Sudden cardiac death, so described
0.645 0.355 0.000
W19.6 Industrial and construction area
0.644 0.356 0.000
I62 Other nontraumatic intracranial haemorrhage
0.643 0.357 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.643 0.357 0.000
Q00-Q07 Congenital malformations of the nervous system
0.643 0.357 0.000
E84 Cystic fibrosis
0.643 0.357 0.000
E79 Disorders of purine and pyrimidine metabolism
0.643 0.357 0.000
E77 Disorders of glycoprotein metabolism
0.643 0.357 0.000
E76 Disorders of glycosaminoglycan metabolism
0.643 0.357 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.643 0.357 0.000
E74 Other disorders of carbohydrate metabolism
0.643 0.357 0.000
E72 Other disorders of amino-acid metabolism
0.643 0.357 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.643 0.357 0.000
E70 Disorders of aromatic amino-acid metabolism
0.643 0.357 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.643 0.357 0.000
M45-M49 Spondylopathies
0.643 0.357 0.000
M30 Polyarteritis nodosa and related conditions
0.640 0.360 0.000
D72 Other disorders of white blood cells
0.639 0.361 0.000
E29 Testicular dysfunction
0.639 0.361 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.638 0.362 0.000
M24 Other specific joint derangements
0.638 0.362 0.000
I86.3 Vulval varices
0.637 0.363 0.000
I86.2 Pelvic varices
0.637 0.363 0.000
I86.0 Sublingual varices
0.637 0.363 0.000
I51.0 Cardiac septal defect, acquired
0.636 0.364 0.000
Q60-Q64 Congenital malformations of the urinary system
0.636 0.364 0.000
D53 Other nutritional anaemias
0.636 0.364 0.000
I51.8 Other ill-defined heart diseases
0.636 0.364 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.635 0.365 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.635 0.365 0.000
F80-F89 Disorders of psychological development
0.635 0.365 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.634 0.366 0.000
I36 Nonrheumatic tricuspid valve disorders
0.633 0.366 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.633 0.366 0.000
I35.1 Aortic (valve) insufficiency
0.633 0.367 0.000
F30-F39 Mood [affective] disorders
0.633 0.367 0.000
I82.3 Embolism and thrombosis of renal vein
0.633 0.367 0.000
I82.1 Thrombophlebitis migrans
0.633 0.367 0.000
I82.0 Budd-Chiari syndrome
0.633 0.367 0.000
M13.8 Other specified arthritis
0.632 0.368 0.000
M25.4 Effusion of joint
0.632 0.368 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.632 0.368 0.000
I51.6 Cardiovascular disease, unspecified
0.630 0.370 0.000
I73 Other peripheral vascular diseases
0.629 0.371 0.000
E85 Amyloidosis
0.629 0.371 0.000
Y83.3 Surgical operation with formation of external stoma
0.629 0.371 0.000
M14 Arthropathies in other diseases classified elsewhere
0.629 0.371 0.000
D52 Folate deficiency anaemia
0.628 0.372 0.000
E23.2 Diabetes insipidus
0.628 0.372 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.628 0.372 0.000
I30.8 Other forms of acute pericarditis
0.626 0.374 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.626 0.374 0.000
M00-M03 Infectious arthropathies
0.626 0.374 0.000
I12.9 Hypertensive renal disease without renal failure
0.626 0.374 0.000
E87.4 Mixed disorder of acid-base balance
0.626 0.374 0.000
O86 Other puerperal infections
0.625 0.374 0.000
E23.6 Other disorders of pituitary gland
0.625 0.375 0.000
I87.8 Other specified disorders of veins
0.623 0.377 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.623 0.377 0.000
O97 Death from sequelae of direct obstetric causes
0.623 0.377 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.623 0.377 0.000
O95 Obstetric death of unspecified cause
0.623 0.377 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.623 0.377 0.000
D84 Other immunodeficiencies
0.622 0.377 0.000
D83 Common variable immunodeficiency
0.622 0.377 0.000
D82 Immunodeficiency associated with other major defects
0.622 0.377 0.000
D81 Combined immunodeficiencies
0.622 0.377 0.000
D55-D59 Haemolytic anaemias
0.622 0.378 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.622 0.378 0.000
B37 Candidiasis
0.622 0.378 0.000
I49.3 Ventricular premature depolarisation
0.622 0.378 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.621 0.378 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.621 0.379 0.000
A15-A19 Tuberculosis
0.619 0.380 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.619 0.381 0.000
B65-B83 Helminthiases
0.619 0.381 0.000
I22 Subsequent myocardial infarction
0.618 0.382 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.617 0.383 0.000
Y48 Anaesthetics and therapeutic gases
0.616 0.383 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.616 0.384 0.000
D73 Diseases of spleen
0.616 0.384 0.000
M33 Dermatopolymyositis
0.616 0.384 0.000
E78.5 Hyperlipidaemia, unspecified
0.616 0.384 0.000
I47.0 Reentry ventricular arrhythmia
0.615 0.385 0.000
G81 Hemiplegia
0.615 0.385 0.000
I45.4 Nonspecific intraventricular block
0.615 0.385 0.000
I45.0 Right fascicular block
0.615 0.385 0.000
I27.0 Primary pulmonary hypertension
0.615 0.385 0.000
V80-V89 Other land transport accidents
0.615 0.385 0.000
B50-B64 Protozoal diseases
0.615 0.385 0.000
F31 Bipolar affective disorder
0.615 0.385 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.615 0.385 0.000
M86-M90 Other osteopathies
0.614 0.386 0.000
I45.2 Bifascicular block
0.614 0.386 0.000
X78 Intentional self-harm by sharp object
0.613 0.386 0.000
E73 Lactose intolerance
0.613 0.387 0.000
G70 Myasthenia gravis and other myoneural disorders
0.612 0.388 0.000
M31 Other necrotising vasculopathies
0.612 0.388 0.000
I27.2 Other secondary pulmonary hypertension
0.612 0.388 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.611 0.389 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.611 0.389 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.610 0.389 0.000
W10.9 Unspecified place
0.610 0.389 0.000
W10.5 Trade and service area
0.610 0.389 0.000
W10.2 School, other institution and public administrative area
0.610 0.389 0.000
W10.0 Home
0.610 0.389 0.000
W10.7 Farm
0.610 0.389 0.000
W10.6 Industrial and construction area
0.610 0.389 0.000
W10.3 Sports and athletics area
0.610 0.389 0.000
W10.1 Residential institution
0.610 0.389 0.000
I70 Atherosclerosis
0.610 0.390 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.610 0.390 0.000
U51 Admission status on psychiatric patients
0.610 0.390 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.609 0.391 0.000
M32 Systemic lupus erythematosus
0.609 0.391 0.000
D74 Methaemoglobinaemia
0.609 0.391 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.609 0.391 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.609 0.391 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.609 0.391 0.000
E34.8 Other specified endocrine disorders
0.608 0.392 0.000
E34.5 Androgen resistance syndrome
0.608 0.392 0.000
E34.4 Constitutional tall stature
0.608 0.392 0.000
E34.3 Short stature, not elsewhere classified
0.608 0.392 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.608 0.392 0.000
E34.1 Other hypersecretion of intestinal hormones
0.608 0.392 0.000
B44.1 Other pulmonary aspergillosis
0.608 0.392 0.000
O92.2 Other and unspecified disorders of breast associated with childbirth
0.608 0.392 0.000
O91 Infections of breast associated with childbirth
0.607 0.392 0.000
O89 Complications of anaesthesia during the puerperium
0.607 0.392 0.000
O88 Obstetric embolism
0.607 0.392 0.000
O85 Puerperal sepsis
0.607 0.392 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.607 0.393 0.000
G80 Infantile cerebral palsy
0.607 0.393 0.000
O80-O84 Delivery
0.607 0.393 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.606 0.394 0.000
Q35-Q37 Cleft lip and cleft palate
0.606 0.394 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.606 0.394 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.605 0.395 0.000
E27.9 Disorder of adrenal gland, unspecified
0.605 0.395 0.000
I05.0 Mitral stenosis
0.605 0.395 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.605 0.395 0.000
M35.7 Hypermobility syndrome
0.605 0.395 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.605 0.395 0.000
M35.5 Multifocal fibrosclerosis
0.605 0.395 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.605 0.395 0.000
M35.2 Behcet's disease
0.605 0.395 0.000
M35.1 Other overlap syndromes
0.605 0.395 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.605 0.395 0.000
M10.99 Gout, unspecified (Site unspecified)
0.605 0.395 0.000
A80-A89 Viral infections of the central nervous system
0.604 0.396 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.604 0.396 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.603 0.397 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.603 0.397 0.000
U50 Level of care administered to neonates
0.603 0.397 0.000
U07 Emergency use of U07
0.603 0.397 0.000
U06 Emergency use of U06
0.603 0.397 0.000
U04 Severe acute respiratory syndrome [SARS]
0.603 0.397 0.000
U52 First in a series of a regular day/night admissions
0.603 0.397 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.603 0.397 0.000
V48 Car occupant injured in noncollision transport accident
0.602 0.398 0.000
E27.2 Addisonian crisis
0.601 0.399 0.000
O87 Venous complications in the puerperium
0.600 0.399 0.000
M13.0 Polyarthritis, unspecified
0.600 0.400 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.600 0.400 0.000
I34.1 Mitral (valve) prolapse
0.599 0.401 0.000
I28 Other diseases of pulmonary vessels
0.599 0.401 0.000
I49.2 Junctional premature depolarisation
0.599 0.401 0.000
I35.9 Aortic valve disorder, unspecified
0.598 0.401 0.000
I72.0 Aneurysm of carotid artery
0.598 0.402 0.000
G40-G47 Episodic and paroxysmal disorders
0.598 0.402 0.000
F99 Mental disorder, not otherwise specified
0.598 0.402 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.597 0.403 0.000
Y54.4 Loop [high-ceiling] diuretics
0.597 0.403 0.000
M25.46 Effusion of joint (Lower leg)
0.597 0.403 0.000
Y59 Other and unspecified vaccines and biological substances
0.596 0.403 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.596 0.403 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.596 0.403 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.596 0.403 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.596 0.403 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.596 0.403 0.000
E27.1 Primary adrenocortical insufficiency
0.596 0.404 0.000
M80-M85 Disorders of bone density and structure
0.596 0.404 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.595 0.405 0.000
W06.0 Home
0.594 0.406 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.594 0.406 0.000
I49.0 Ventricular fibrillation and flutter
0.593 0.407 0.000
I06 Rheumatic aortic valve diseases
0.593 0.407 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.593 0.407 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.592 0.408 0.000
G06.1 Intraspinal abscess and granuloma
0.589 0.411 0.000
V23.4 Driver injured in traffic accident
0.589 0.411 0.000
G90 Disorders of autonomic nervous system
0.588 0.412 0.000
O42 Premature rupture of membranes
0.587 0.413 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.587 0.413 0.000
W07 Fall involving chair
0.587 0.413 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.587 0.413 0.000
E11 Non-insulin-dependent diabetes mellitus
0.587 0.413 0.000
M12 Other specific arthropathies
0.587 0.413 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.587 0.413 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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