TreeWAS – Variant ID: rs7407664

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.999	0.001
Chapter IX Diseases of the circulatory system	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
I60-I69 Cerebrovascular diseases	0.995	0.005
Chapter VI Diseases of the nervous system	0.993	0.007
O60-O75 Complications of labour and delivery	0.988	0.012
I30-I52 Other forms of heart disease	0.985	0.015
S00-S09 Injuries to the head	0.983	0.017
G40-G47 Episodic and paroxysmal disorders	0.981	0.019
E00-E07 Disorders of thyroid gland	0.978	0.022
G47 Sleep disorders	0.975	0.025
G47.3 Sleep apnoea	0.971	0.029
E65-E68 Obesity and other hyperalimentation	0.964	0.036
O70 Perineal laceration during delivery	0.963	0.037
E03 Other hypothyroidism	0.956	0.044
I51 Complications and ill-defined descriptions of heart disease	0.955	0.045
S00 Superficial injury of head	0.955	0.045
I61 Intracerebral haemorrhage	0.953	0.047
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.948	0.052
O70.1 Second degree perineal laceration during delivery	0.945	0.055
E66 Obesity	0.941	0.059
E03.9 Hypothyroidism, unspecified	0.939	0.061
E66.8 Other obesity	0.935	0.065
S80-S89 Injuries to the knee and lower leg	0.931	0.069
I42 Cardiomyopathy	0.930	0.070
E20-E35 Disorders of other endocrine glands	0.930	0.070
I51.8 Other ill-defined heart diseases	0.926	0.074
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.926	0.074
O68 Labour and delivery complicated by foetal stress [distress]	0.918	0.082
G90-G99 Other disorders of the nervous system	0.907	0.093
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.892	0.108
M20-M25 Other joint disorders	0.891	0.109
S20-S29 Injuries to the thorax	0.890	0.110
S50-S59 Injuries to the elbow and forearm	0.889	0.111
E04 Other non-toxic goitre	0.886	0.114
O48 Prolonged pregnancy	0.884	0.116
I63 Cerebral infarction	0.880	0.120
I61.9 Intracerebral haemorrhage, unspecified	0.877	0.123
I60 Subarachnoid haemorrhage	0.875	0.125
S02 Fracture of skull and facial bones	0.871	0.129
O72 Postpartum haemorrhage	0.870	0.130
S00.0 Superficial injury of scalp	0.866	0.134
G44 Other headache syndromes	0.864	0.136
S00.8 Superficial injury of other parts of head	0.859	0.141
O20-O29 Other maternal disorders predominantly related to pregnancy	0.857	0.143
I67 Other cerebrovascular diseases	0.855	0.145
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.853	0.147
E04.9 Non-toxic goitre, unspecified	0.848	0.152
S09 Other and unspecified injuries of head	0.843	0.157
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.843	0.157
I42.9 Cardiomyopathy, unspecified	0.839	0.161
G35-G37 Demyelinating diseases of the central nervous system	0.837	0.163
I35 Nonrheumatic aortic valve disorders	0.837	0.163
I49 Other cardiac arrhythmias	0.835	0.165
Chapter VIII Diseases of the ear and mastoid process	0.826	0.174
I20-I25 Ischaemic heart diseases	0.825	0.175
I63.9 Cerebral infarction, unspecified	0.821	0.179
M25 Other joint disorders, not elsewhere classified	0.821	0.179
I67.1 Cerebral aneurysm, nonruptured	0.820	0.180
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.817	0.183
I38 Endocarditis, valve unspecified	0.816	0.184
S81 Open wound of lower leg	0.811	0.189
Chapter XXII Codes for special purposes	0.810	0.190
E27 Other disorders of adrenal gland	0.808	0.192
I61.8 Other intracerebral haemorrhage	0.807	0.193
M05-M14 Inflammatory polyarthropathies	0.802	0.198
S90-S99 Injuries to the ankle and foot	0.799	0.201
I70-I79 Diseases of arteries, arterioles and capillaries	0.797	0.203
S80 Superficial injury of lower leg	0.795	0.205
I51.7 Cardiomegaly	0.792	0.208
E40-E46 Malnutrition	0.792	0.208
M23 Internal derangement of knee	0.790	0.210
S02.6 Fracture of mandible	0.789	0.211
I64 Stroke, not specified as haemorrhage or infarction	0.788	0.212
I95-I99 Other and unspecified disorders of the circulatory system	0.786	0.214
O70.2 Third degree perineal laceration during delivery	0.785	0.215
O70.9 Perineal laceration during delivery, unspecified	0.785	0.215
E29 Testicular dysfunction	0.782	0.218
O72.2 Delayed and secondary postpartum haemorrhage	0.774	0.225
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.774	0.226
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.772	0.228
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.771	0.229
I42.0 Dilated cardiomyopathy	0.764	0.236
O62 Abnormalities of forces of labour	0.764	0.236
I24 Other acute ischaemic heart diseases	0.764	0.236
G90 Disorders of autonomic nervous system	0.762	0.238
S10-S19 Injuries to the neck	0.760	0.240
G93 Other disorders of brain	0.760	0.240
M06 Other rheumatoid arthritis	0.760	0.240
I60.9 Subarachnoid haemorrhage, unspecified	0.760	0.240
G41 Status epilepticus	0.759	0.241
O46 Antepartum haemorrhage, not elsewhere classified	0.757	0.243
O35 Maternal care for known or suspected foetal abnormality and damage	0.757	0.243
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.756	0.244
E22 Hyperfunction of pituitary gland	0.756	0.244
S00.3 Superficial injury of nose	0.756	0.244
S20 Superficial injury of thorax	0.756	0.244
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.754	0.246
G70-G73 Diseases of myoneural junction and muscle	0.751	0.249
G20-G26 Extrapyramidal and movement disorders	0.751	0.249
O85-O92 Complications predominantly related to the puerperium	0.750	0.250
G47.1 Disorders of excessive somnolence [hypersomnias]	0.750	0.250
S89 Other and unspecified injuries of lower leg	0.749	0.251
I49.0 Ventricular fibrillation and flutter	0.748	0.252
T15-T19 Effects of foreign body entering through natural orifice	0.747	0.253
I62 Other nontraumatic intracranial haemorrhage	0.746	0.254
O30 Multiple gestation	0.746	0.254
I42.1 Obstructive hypertrophic cardiomyopathy	0.745	0.254
O75 Other complications of labour and delivery, not elsewhere classified	0.744	0.256
S00.1 Contusion of eyelid and periocular area	0.742	0.258
O47 False labour	0.741	0.258
M06.9 Rheumatoid arthritis, unspecified	0.741	0.259
S52 Fracture of forearm	0.736	0.264
I33 Acute and subacute endocarditis	0.735	0.265
G40 Epilepsy	0.734	0.266
I27 Other pulmonary heart diseases	0.733	0.267
S27 Injury of other and unspecified intrathoracic organs	0.733	0.267
O40 Polyhydramnios	0.732	0.267
M40-M43 Deforming dorsopathies	0.732	0.268
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.731	0.269
S02.60 Fracture of mandible (closed)	0.730	0.270
S50 Superficial injury of forearm	0.728	0.272
S09.9 Unspecified injury of head	0.728	0.272
M25.7 Osteophyte	0.728	0.272
H80-H83 Diseases of inner ear	0.727	0.273
G47.8 Other sleep disorders	0.726	0.274
S05 Injury of eye and orbit	0.726	0.274
S32 Fracture of lumbar spine and pelvis	0.726	0.274
M60-M63 Disorders of muscles	0.724	0.275
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.722	0.278
O21 Excessive vomiting in pregnancy	0.721	0.279
M86-M90 Other osteopathies	0.720	0.280
G00-G09 Inflammatory diseases of the central nervous system	0.720	0.280
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.284
I60.8 Other subarachnoid haemorrhage	0.716	0.284
G80-G83 Cerebral palsy and other paralytic syndromes	0.716	0.284
I25 Chronic ischaemic heart disease	0.716	0.284
E06 Thyroiditis	0.715	0.285
S30 Superficial injury of abdomen, lower back and pelvis	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
G44.2 Tension-type headache	0.714	0.285
I72 Other aneurysm	0.714	0.286
O44 Placenta praevia	0.714	0.286
Q20-Q28 Congenital malformations of the circulatory system	0.714	0.286
I68 Cerebrovascular disorders in diseases classified elsewhere	0.713	0.287
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.713	0.287
M23.4 Loose body in knee	0.713	0.287
I05-I09 Chronic rheumatic heart diseases	0.713	0.287
O94-O99 Other obstetric conditions, not elsewhere classified	0.712	0.288
O74 Complications of anaesthesia during labour and delivery	0.708	0.291
O71 Other obstetric trauma	0.708	0.291
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.708	0.291
O65 Obstructed labour due to maternal pelvic abnormality	0.708	0.291
O61 Failed induction of labour	0.708	0.291
O60 Preterm delivery	0.708	0.291
M35 Other systemic involvement of connective tissue	0.707	0.293
T79-T79 Certain early complications of trauma	0.707	0.293
I52 Other heart disorders in diseases classified elsewhere	0.706	0.294
I48 Atrial fibrillation and flutter	0.706	0.294
I43 Cardiomyopathy in diseases classified elsewhere	0.706	0.294
I41 Myocarditis in diseases classified elsewhere	0.706	0.294
I40 Acute myocarditis	0.706	0.294
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.706	0.294
I37 Pulmonary valve disorders	0.706	0.294
I36 Nonrheumatic tricuspid valve disorders	0.706	0.294
I32 Pericarditis in diseases classified elsewhere	0.706	0.294
S08 Traumatic amputation of part of head	0.705	0.295
S07 Crushing injury of head	0.705	0.295
S04 Injury of cranial nerves	0.705	0.295
S03 Dislocation, sprain and strain of joints and ligaments of head	0.705	0.295
O36 Maternal care for other known or suspected foetal problems	0.705	0.295
G46 Vascular syndromes of brain in cerebrovascular diseases	0.704	0.296
M34 Systemic sclerosis	0.702	0.298
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.701	0.298
E00 Congenital iodine-deficiency syndrome	0.701	0.298
E02 Subclinical iodine-deficiency hypothyroidism	0.701	0.298
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.701	0.299
G37 Other demyelinating diseases of central nervous system	0.699	0.301
G47.4 Narcolepsy and cataplexy	0.699	0.301
G47.2 Disorders of the sleep-wake schedule	0.699	0.301
I49.5 Sick sinus syndrome	0.699	0.301
M45-M49 Spondylopathies	0.698	0.302
E50-E64 Other nutritional deficiencies	0.697	0.303
O64 Obstructed labour due to malposition and malpresentation of foetus	0.697	0.303
O72.0 Third-stage haemorrhage	0.696	0.303
S31 Open wound of abdomen, lower back and pelvis	0.696	0.304
S00.2 Other superficial injuries of eyelid and periocular area	0.696	0.304
I35.0 Aortic (valve) stenosis	0.695	0.305
E27.1 Primary adrenocortical insufficiency	0.694	0.306
G96 Other disorders of central nervous system	0.694	0.306
M23.8 Other internal derangements of knee	0.693	0.306
S82 Fracture of lower leg, including ankle	0.692	0.308
I61.5 Intracerebral haemorrhage, intraventricular	0.692	0.308
S51 Open wound of forearm	0.691	0.309
E67 Other hyperalimentation	0.691	0.309
E68 Sequelae of hyperalimentation	0.691	0.309
E65 Localised adiposity	0.691	0.309
O70.3 Fourth degree perineal laceration during delivery	0.690	0.309
G44.4 Drug-induced headache, not elsewhere classified	0.690	0.310
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.686	0.314
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.686	0.314
E03.8 Other specified hypothyroidism	0.685	0.315
E03.5 Myxoedema coma	0.685	0.315
E03.4 Atrophy of thyroid (acquired)	0.685	0.315
E03.3 Postinfectious hypothyroidism	0.685	0.315
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.685	0.315
E03.1 Congenital hypothyroidism without goitre	0.685	0.315
E03.0 Congenital hypothyroidism with diffuse goitre	0.685	0.315
I51.6 Cardiovascular disease, unspecified	0.685	0.315
I51.5 Myocardial degeneration	0.685	0.315
I51.4 Myocarditis, unspecified	0.685	0.315
I51.3 Intracardiac thrombosis, not elsewhere classified	0.685	0.315
I51.2 Rupture of papillary muscle, not elsewhere classified	0.685	0.315
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.685	0.315
I51.0 Cardiac septal defect, acquired	0.685	0.315
S00.7 Multiple superficial injuries of head	0.684	0.315
S00.5 Superficial injury of lip and oral cavity	0.684	0.315
S00.4 Superficial injury of ear	0.684	0.315
G91 Hydrocephalus	0.684	0.316
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.684	0.316
I61.6 Intracerebral haemorrhage, multiple localised	0.684	0.316
I61.4 Intracerebral haemorrhage in cerebellum	0.684	0.316
I61.3 Intracerebral haemorrhage in brain stem	0.684	0.316
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.684	0.316
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.684	0.316
I42.8 Other cardiomyopathies	0.684	0.316
S81.0 Open wound of knee	0.682	0.318
M24 Other specific joint derangements	0.682	0.318
O43 Placental disorders	0.682	0.318
M21 Other acquired deformities of limbs	0.681	0.318
O28 Abnormal findings on antenatal screening of mother	0.681	0.319
O73 Retained placenta and membranes, without haemorrhage	0.681	0.319
O45 Premature separation of placenta [abruptio placentae]	0.680	0.320
O33 Maternal care for known or suspected disproportion	0.680	0.320
O31 Complications specific to multiple gestation	0.680	0.320
G44.8 Other specified headache syndromes	0.680	0.320
I47 Paroxysmal tachycardia	0.679	0.321
S02.3 Fracture of orbital floor	0.679	0.321
I49.3 Ventricular premature depolarisation	0.677	0.323
S29 Other and unspecified injuries of thorax	0.677	0.323
E29.1 Testicular hypofunction	0.676	0.324
I63.8 Other cerebral infarction	0.675	0.324
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.675	0.325
E66.2 Extreme obesity with alveolar hypoventilation	0.675	0.325
E66.1 Drug-induced obesity	0.675	0.325
E66.0 Obesity due to excess calories	0.675	0.325
E04.0 Non-toxic diffuse goitre	0.674	0.325
S02.8 Fractures of other skull and facial bones	0.672	0.328
O20 Haemorrhage in early pregnancy	0.671	0.329
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.671	0.329
M80-M85 Disorders of bone density and structure	0.670	0.330
I71 Aortic aneurysm and dissection	0.668	0.332
S88 Traumatic amputation of lower leg	0.667	0.333
S87 Crushing injury of lower leg	0.667	0.333
S86 Injury of muscle and tendon at lower leg level	0.667	0.333
S85 Injury of blood vessels at lower leg level	0.667	0.333
S84 Injury of nerves at lower leg level	0.667	0.333
I42.7 Cardiomyopathy due to drugs and other external agents	0.667	0.333
I42.6 Alcoholic cardiomyopathy	0.667	0.333
I42.5 Other restrictive cardiomyopathy	0.667	0.333
I42.4 Endocardial fibroelastosis	0.667	0.333
I42.3 Endomyocardial (eosinophilic) disease	0.667	0.333
E35 Disorders of endocrine glands in diseases classified elsewhere	0.667	0.333
E34 Other endocrine disorders	0.667	0.333
E32 Diseases of thymus	0.667	0.333
E31 Polyglandular dysfunction	0.667	0.333
E30 Disorders of puberty, not elsewhere classified	0.667	0.333
E26 Hyperaldosteronism	0.667	0.333
E25 Adrenogenital disorders	0.667	0.333
E24 Cushing's syndrome	0.667	0.333
E20 Hypoparathyroidism	0.667	0.333
I69 Sequelae of cerebrovascular disease	0.666	0.334
M25.6 Stiffness of joint, not elsewhere classified	0.665	0.335
I46 Cardiac arrest	0.665	0.335
I25.9 Chronic ischaemic heart disease, unspecified	0.665	0.335
O34 Maternal care for known or suspected abnormality of pelvic organs	0.664	0.336
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.663	0.337
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.663	0.337
I42.2 Other hypertrophic cardiomyopathy	0.662	0.338
S81.8 Open wound of other parts of lower leg	0.662	0.338
S80.1 Contusion of other and unspecified parts of lower leg	0.661	0.339
G95 Other diseases of spinal cord	0.660	0.340
M23.49 Loose body in knee-Unspec lig/men	0.658	0.342
S20.8 Superficial injuries of other and unspecified parts of thorax	0.658	0.342
I30 Acute pericarditis	0.658	0.342
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.658	0.342
I35.2 Aortic (valve) stenosis with insufficiency	0.658	0.342
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.658	0.342
S52.0 Fracture of upper end of ulna	0.657	0.343
S40-S49 Injuries to the shoulder and upper arm	0.656	0.343
H81 Disorders of vestibular function	0.656	0.344
I35.9 Aortic valve disorder, unspecified	0.655	0.345
O00-O08 Pregnancy with abortive outcome	0.655	0.345
O66 Other obstructed labour	0.652	0.348
S70-S79 Injuries to the hip and thigh	0.652	0.348
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.652	0.348
I24.8 Other forms of acute ischaemic heart disease	0.652	0.348
G61 Inflammatory polyneuropathy	0.651	0.348
Q50-Q56 Congenital malformations of genital organs	0.650	0.349
G94 Other disorders of brain in diseases classified elsewhere	0.650	0.350
G98 Other disorders of nervous system, not elsewhere classified	0.650	0.350
G92 Toxic encephalopathy	0.650	0.350
M00-M03 Infectious arthropathies	0.649	0.351
E21.3 Hyperparathyroidism, unspecified	0.648	0.352
I95 Hypotension	0.647	0.353
E46 Unspecified protein-energy malnutrition	0.646	0.354
H65-H75 Diseases of middle ear and mastoid	0.646	0.354
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.646	0.354
I74 Arterial embolism and thrombosis	0.646	0.354
G35 Multiple sclerosis	0.644	0.356
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.644	0.356
I24.9 Acute ischaemic heart disease, unspecified	0.644	0.356
S80.8 Other superficial injuries of lower leg	0.644	0.356
S52.7 Multiple fractures of forearm	0.642	0.358
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.642	0.358
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.641	0.359
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.640	0.360
S37 Injury of urinary and pelvic organs	0.640	0.360
S36 Injury of intra-abdominal organs	0.640	0.360
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.640	0.360
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.640	0.360
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.640	0.360
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.639	0.361
M33 Dermatopolymyositis	0.639	0.361
M32 Systemic lupus erythematosus	0.639	0.361
M30 Polyarteritis nodosa and related conditions	0.639	0.361
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.639	0.361
M25.9 Joint disorder, unspecified	0.639	0.361
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.638	0.361
S26 Injury of heart	0.638	0.361
S25 Injury of blood vessels of thorax	0.638	0.361
S24 Injury of nerves and spinal cord at thorax level	0.638	0.361
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.638	0.361
S21 Open wound of thorax	0.638	0.361
M23.6 Other spontaneous disruption of ligament(s) of knee	0.638	0.362
S59 Other and unspecified injuries of forearm	0.637	0.362
S58 Traumatic amputation of forearm	0.637	0.362
S57 Crushing injury of forearm	0.637	0.362
S56 Injury of muscle and tendon at forearm level	0.637	0.362
S55 Injury of blood vessels at forearm level	0.637	0.362
S54 Injury of nerves at forearm level	0.637	0.362
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.637	0.362
S00.9 Superficial injury of head, part unspecified	0.637	0.363
G90.2 Horner's syndrome	0.637	0.363
I27.8 Other specified pulmonary heart diseases	0.636	0.364
E04.8 Other specified non-toxic goitre	0.635	0.365
S09.8 Other specified injuries of head	0.635	0.365
M31 Other necrotising vasculopathies	0.634	0.366
M25.78 Osteophyte (Other)	0.633	0.367
M25.8 Other specified joint disorders	0.631	0.369
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.631	0.369
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.631	0.369
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.631	0.369
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.631	0.369
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.631	0.369
S32.5 Fracture of pubis	0.630	0.370
G93.8 Other specified disorders of brain	0.629	0.371
I31 Other diseases of pericardium	0.629	0.371
M50-M54 Other dorsopathies	0.628	0.372
E27.8 Other specified disorders of adrenal gland	0.628	0.372
G99 Other disorders of nervous system in diseases classified elsewhere	0.628	0.372
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.627	0.372
E07 Other disorders of thyroid	0.627	0.373
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.627	0.373
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.627	0.373
I60.5 Subarachnoid haemorrhage from vertebral artery	0.627	0.373
I60.4 Subarachnoid haemorrhage from basilar artery	0.627	0.373
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.627	0.373
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.627	0.373
S06 Intracranial injury	0.626	0.374
O47.1 False labour at or after 37 completed weeks of gestation	0.625	0.375
Q38-Q45 Other congenital malformations of the digestive system	0.625	0.375
S02.9 Fracture of skull and facial bones, part unspecified	0.625	0.375
S02.7 Multiple fractures involving skull and facial bones	0.625	0.375
S02.0 Fracture of vault of skull	0.624	0.375
O41 Other disorders of amniotic fluid and membranes	0.624	0.376
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.624	0.376
O72.3 Postpartum coagulation defects	0.624	0.376
O21.0 Mild hyperemesis gravidarum	0.624	0.376
I51.9 Heart disease, unspecified	0.624	0.376
M43 Other deforming dorsopathies	0.623	0.377
M25.5 Pain in joint	0.622	0.377
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.622	0.378
G93.4 Encephalopathy, unspecified	0.621	0.379
S22 Fracture of rib(s), sternum and thoracic spine	0.621	0.379
S27.0 Traumatic pneumothorax	0.621	0.379
O46.9 Antepartum haemorrhage, unspecified	0.620	0.380
I35.8 Other aortic valve disorders	0.620	0.380
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.620	0.380
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.619	0.381
G44.3 Chronic posttraumatic headache	0.619	0.381
G44.1 Vascular headache, not elsewhere classified	0.619	0.381
I67.2 Cerebral atherosclerosis	0.619	0.381
O36.6 Maternal care for excessive foetal growth	0.615	0.384
E05 Thyrotoxicosis [hyperthyroidism]	0.615	0.385
O29 Complications of anaesthesia during pregnancy	0.615	0.385
O23 Infections of genito-urinary tract in pregnancy	0.615	0.385
O22 Venous complications in pregnancy	0.615	0.385
O25 Malnutrition in pregnancy	0.615	0.385
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.614	0.386
S02.5 Fracture of tooth	0.614	0.386
I67.7 Cerebral arteritis, not elsewhere classified	0.613	0.387
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.613	0.387
I67.5 Moyamoya disease	0.613	0.387
I67.4 Hypertensive encephalopathy	0.613	0.387
I67.3 Progressive vascular leukoencephalopathy	0.613	0.387
I67.0 Dissection of cerebral arteries, nonruptured	0.613	0.387
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.612	0.387
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.612	0.388
Q35-Q37 Cleft lip and cleft palate	0.612	0.388
Q30-Q34 Congenital malformations of the respiratory system	0.612	0.388
E04.1 Non-toxic single thyroid nodule	0.611	0.389
M25.55 Pain in joint (Pelvic region and thigh)	0.611	0.389
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.610	0.390
I72.4 Aneurysm of artery of lower extremity	0.609	0.391
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.609	0.391
O69 Labour and delivery complicated by umbilical cord complications	0.609	0.391
M91-M94 Chondropathies	0.608	0.391
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.608	0.392
S92 Fracture of foot, except ankle	0.608	0.392
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.607	0.393
G44.0 Cluster headache syndrome	0.607	0.393
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.606	0.394
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.605	0.395
S09.7 Multiple injuries of head	0.604	0.395
S09.2 Traumatic rupture of ear drum	0.604	0.395
S09.1 Injury of muscle and tendon of head	0.604	0.395
S09.0 Injury of blood vessels of head, not elsewhere classified	0.604	0.395
S02.1 Fracture of base of skull	0.604	0.396
O24 Diabetes mellitus in pregnancy	0.603	0.396
G93.9 Disorder of brain, unspecified	0.602	0.398
S91 Open wound of ankle and foot	0.601	0.398
S52.00 Fracture of upper end of ulna (closed)	0.601	0.398
E23 Hypofunction and other disorders of pituitary gland	0.601	0.399
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.601	0.399
O30.0 Twin pregnancy	0.601	0.399
G72 Other myopathies	0.600	0.399
G36 Other acute disseminated demyelination	0.600	0.400
G41.9 Status epilepticus, unspecified	0.599	0.401
O32 Maternal care for known or suspected malpresentation of foetus	0.599	0.401
I49.2 Junctional premature depolarisation	0.598	0.401
Q80-Q89 Other congenital malformations	0.597	0.403
S10 Superficial injury of neck	0.597	0.403
O16 Unspecified maternal hypertension	0.595	0.405
T66-T78 Other and unspecified effects of external causes	0.594	0.406
M25.3 Other instability of joint	0.594	0.406
M23.9 Internal derangement of knee, unspecified	0.594	0.406
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.593	0.407
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.593	0.407
I23 Certain current complications following acute myocardial infarction	0.592	0.408
I44 Atrioventricular and left bundle-branch block	0.591	0.409
I67.8 Other specified cerebrovascular diseases	0.591	0.409
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.591	0.409
I49.4 Other and unspecified premature depolarisation	0.590	0.410
I95.1 Orthostatic hypotension	0.590	0.410
H81.1 Benign paroxysmal vertigo	0.590	0.410
Q60-Q64 Congenital malformations of the urinary system	0.589	0.411
M25.2 Flail joint	0.588	0.411
M25.1 Fistula of joint	0.588	0.411
M25.0 Haemarthrosis	0.588	0.411
T91 Sequelae of injuries of neck and trunk	0.588	0.412
S89.8 Other specified injuries of lower leg	0.588	0.412
S01 Open wound of head	0.587	0.413
I28 Other diseases of pulmonary vessels	0.586	0.414
S02.4 Fracture of malar and maxillary bones	0.585	0.414
H90-H95 Other disorders of ear	0.585	0.415
S02.2 Fracture of nasal bones	0.584	0.415
M25.74 Osteophyte (Hand)	0.584	0.416
E27.4 Other and unspecified adrenocortical insufficiency	0.584	0.416
S50.9 Superficial injury of forearm, unspecified	0.583	0.417
I22 Subsequent myocardial infarction	0.583	0.417
I70 Atherosclerosis	0.582	0.418
G90.9 Disorder of autonomic nervous system, unspecified	0.582	0.418
O62.2 Other uterine inertia	0.581	0.419
S81.7 Multiple open wounds of lower leg	0.581	0.419
M35.7 Hypermobility syndrome	0.581	0.419
M62 Other disorders of muscle	0.580	0.420
G20 Parkinson's disease	0.580	0.420
E21.0 Primary hyperparathyroidism	0.580	0.420
E27.9 Disorder of adrenal gland, unspecified	0.579	0.421
E27.5 Adrenomedullary hyperfunction	0.579	0.421
E27.3 Drug-induced adrenocortical insufficiency	0.579	0.421
E27.2 Addisonian crisis	0.579	0.421
E27.0 Other adrenocortical overactivity	0.579	0.421
S89.9 Unspecified injury of lower leg	0.578	0.422
E22.1 Hyperprolactinaemia	0.578	0.422
I27.2 Other secondary pulmonary hypertension	0.577	0.423
S82.0 Fracture of patella	0.577	0.423
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.577	0.423
M14 Arthropathies in other diseases classified elsewhere	0.575	0.425
M12 Other specific arthropathies	0.575	0.425
M09 Juvenile arthritis in diseases classified elsewhere	0.575	0.425
M08 Juvenile arthritis	0.575	0.425

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations