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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74284780
log Bayes Factor = 9.43097
Chromosome 4   position 6,937,801  (GRCh37) Explore rs74284780 on Ensembl!
Variant rs74284780 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
D50-D53 Nutritional anaemias
0.997 0.003 0.000
C18 Malignant neoplasm of colon
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.997 0.003 0.000
D50 Iron deficiency anaemia
0.995 0.005 0.000
D50.8 Other iron deficiency anaemias
0.991 0.009 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.984 0.016 0.000
K22 Other diseases of oesophagus
0.984 0.016 0.000
C18.7 Sigmoid colon
0.983 0.017 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.982 0.018 0.000
K22.1 Ulcer of oesophagus
0.981 0.019 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
N17-N19 Renal failure
0.977 0.023 0.000
Chapter XI Diseases of the digestive system
0.976 0.024 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.976 0.024 0.000
K31 Other diseases of stomach and duodenum
0.973 0.027 0.000
N18 Chronic renal failure
0.971 0.029 0.000
S00 Superficial injury of head
0.970 0.030 0.000
Chapter V Mental and behavioural disorders
0.963 0.037 0.000
D60-D64 Aplastic and other anaemias
0.957 0.043 0.000
N18.9 Chronic renal failure, unspecified
0.955 0.045 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.953 0.047 0.000
C77.2 Intra-abdominal lymph nodes
0.952 0.048 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.949 0.051 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.949 0.051 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.947 0.053 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.946 0.054 0.000
K31.8 Other specified diseases of stomach and duodenum
0.944 0.056 0.000
K22.7 Barrett's oesophagus
0.943 0.057 0.000
S00.8 Superficial injury of other parts of head
0.939 0.061 0.000
C79 Secondary malignant neoplasm of other sites
0.934 0.066 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.923 0.077 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.921 0.079 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.920 0.080 0.000
C18.0 Caecum
0.920 0.080 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.916 0.084 0.000
C18.9 Colon, unspecified
0.911 0.089 0.000
Chapter XXII Codes for special purposes
0.907 0.093 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.901 0.099 0.000
K21 Gastro-oesophageal reflux disease
0.900 0.100 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.898 0.102 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.894 0.106 0.000
C77.8 Lymph nodes of multiple regions
0.893 0.107 0.000
D62 Acute posthaemorrhagic anaemia
0.893 0.107 0.000
C78.7 Secondary malignant neoplasm of liver
0.890 0.110 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.888 0.112 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.888 0.112 0.000
C15 Malignant neoplasm of oesophagus
0.886 0.114 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.885 0.115 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.882 0.118 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.881 0.119 0.000
D51 Vitamin B12 deficiency anaemia
0.881 0.119 0.000
N88 Other noninflammatory disorders of cervix uteri
0.868 0.132 0.000
A30-A49 Other bacterial diseases
0.868 0.132 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.867 0.133 0.000
N94.6 Dysmenorrhoea, unspecified
0.865 0.135 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.864 0.136 0.000
T81 Complications of procedures, not elsewhere classified
0.858 0.142 0.000
K50-K52 Noninfective enteritis and colitis
0.856 0.144 0.000
L20-L30 Dermatitis and eczema
0.855 0.145 0.000
N10-N16 Renal tubulo-interstitial diseases
0.851 0.149 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.846 0.154 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.846 0.154 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.845 0.155 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.845 0.155 0.000
F03 Unspecified dementia
0.839 0.161 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.833 0.167 0.000
K52 Other non-infective gastro-enteritis and colitis
0.832 0.168 0.000
S20-S29 Injuries to the thorax
0.830 0.170 0.000
F20 Schizophrenia
0.828 0.172 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.827 0.173 0.000
S00.0 Superficial injury of scalp
0.826 0.174 0.000
B99-B99 Other infectious diseases
0.825 0.175 0.000
N88.2 Stricture and stenosis of cervix uteri
0.824 0.176 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.824 0.176 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.823 0.177 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.820 0.180 0.000
B07 Viral warts
0.819 0.181 0.000
N19 Unspecified renal failure
0.817 0.183 0.000
N18.5 Chronic kidney disease, stage 5
0.815 0.185 0.000
N18.0 End-stage renal disease
0.814 0.186 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.812 0.188 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.812 0.188 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.812 0.188 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.810 0.190 0.000
N99-N99 Other disorders of the genitourinary system
0.806 0.194 0.000
S00.1 Contusion of eyelid and periocular area
0.804 0.196 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.803 0.197 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.801 0.199 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.799 0.201 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.799 0.201 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.798 0.202 0.000
M20-M25 Other joint disorders
0.794 0.206 0.000
C20 Malignant neoplasm of rectum
0.793 0.207 0.000
L89 Decubitus ulcer
0.786 0.214 0.000
A40 Streptococcal septicaemia
0.784 0.216 0.000
N20-N23 Urolithiasis
0.784 0.216 0.000
L30 Other dermatitis
0.784 0.216 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.784 0.216 0.000
K22.2 Oesophageal obstruction
0.782 0.218 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.781 0.219 0.000
T79-T79 Certain early complications of trauma
0.779 0.221 0.000
S02 Fracture of skull and facial bones
0.775 0.225 0.000
K22.9 Disease of oesophagus, unspecified
0.774 0.226 0.000
F25 Schizoaffective disorders
0.774 0.226 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.772 0.228 0.000
C15.9 Oesophagus, unspecified
0.772 0.228 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.769 0.231 0.000
C77.0 Lymph nodes of head, face and neck
0.769 0.231 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.769 0.231 0.000
S00.7 Multiple superficial injuries of head
0.768 0.232 0.000
D64 Other anaemias
0.767 0.233 0.000
D50.9 Iron deficiency anaemia, unspecified
0.767 0.233 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.766 0.234 0.000
F23 Acute and transient psychotic disorders
0.763 0.237 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.761 0.239 0.000
N94.3 Premenstrual tension syndrome
0.760 0.240 0.000
C18.4 Transverse colon
0.760 0.240 0.000
K22.8 Other specified diseases of oesophagus
0.759 0.240 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.759 0.241 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.758 0.242 0.000
F80-F89 Disorders of psychological development
0.756 0.244 0.000
M65-M68 Disorders of synovium and tendon
0.754 0.246 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.754 0.246 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.753 0.247 0.000
C80 Malignant neoplasm without specification of site
0.752 0.248 0.000
N18.3 Chronic kidney disease, stage 3
0.751 0.249 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.751 0.249 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.750 0.249 0.000
N13 Obstructive and reflux uropathy
0.750 0.250 0.000
L60-L75 Disorders of skin appendages
0.750 0.250 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.750 0.250 0.000
T43.2 Other and unspecified antidepressants
0.748 0.252 0.000
C18.3 Hepatic flexure
0.747 0.253 0.000
B15-B19 Viral hepatitis
0.746 0.253 0.000
C77.9 Lymph node, unspecified
0.746 0.254 0.000
S00.3 Superficial injury of nose
0.746 0.254 0.000
S05 Injury of eye and orbit
0.746 0.254 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.744 0.256 0.000
F20.9 Schizophrenia, unspecified
0.742 0.258 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.739 0.261 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.737 0.262 0.000
D55-D59 Haemolytic anaemias
0.736 0.264 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.735 0.265 0.000
S40-S49 Injuries to the shoulder and upper arm
0.735 0.265 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.735 0.265 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.735 0.265 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.734 0.266 0.000
L30.9 Dermatitis, unspecified
0.733 0.267 0.000
F60-F69 Disorders of adult personality and behaviour
0.733 0.267 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.733 0.267 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.732 0.268 0.000
S00.5 Superficial injury of lip and oral cavity
0.731 0.269 0.000
N94.4 Primary dysmenorrhoea
0.730 0.270 0.000
C18.2 Ascending colon
0.730 0.270 0.000
Q00-Q07 Congenital malformations of the nervous system
0.726 0.273 0.000
Chapter VIII Diseases of the ear and mastoid process
0.726 0.274 0.000
M24 Other specific joint derangements
0.725 0.274 0.000
U80 Agent resistant to penicillin and related antibiotics
0.723 0.277 0.000
C77.4 Inguinal and lower limb lymph nodes
0.722 0.278 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.721 0.279 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.721 0.279 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.721 0.279 0.000
C91 Lymphoid leukaemia
0.719 0.281 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.719 0.281 0.000
U51 Admission status on psychiatric patients
0.717 0.282 0.000
L27 Dermatitis due to substances taken internally
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
C17 Malignant neoplasm of small intestine
0.716 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.716 0.284 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.716 0.284 0.000
D53 Other nutritional anaemias
0.715 0.285 0.000
C18.8 Overlapping lesion of colon
0.715 0.285 0.000
C18.1 Appendix
0.715 0.285 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.715 0.285 0.000
D50.1 Sideropenic dysphagia
0.713 0.287 0.000
B25-B34 Other viral diseases
0.713 0.287 0.000
L89.1 Stage II decubitus ulcer
0.712 0.288 0.000
C78.0 Secondary malignant neoplasm of lung
0.709 0.291 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.709 0.291 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.708 0.292 0.000
C21 Malignant neoplasm of anus and anal canal
0.708 0.292 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.707 0.293 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.706 0.294 0.000
K22.3 Perforation of oesophagus
0.705 0.295 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.704 0.296 0.000
K28 Gastrojejunal ulcer
0.704 0.296 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.704 0.296 0.000
T31 Burns classified according to extent of body surface involved
0.704 0.296 0.000
C18.5 Splenic flexure
0.704 0.296 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.702 0.297 0.000
K22.4 Dyskinesia of oesophagus
0.701 0.298 0.000
K25 Gastric ulcer
0.701 0.299 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.701 0.299 0.000
S07 Crushing injury of head
0.701 0.299 0.000
S04 Injury of cranial nerves
0.701 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.299 0.000
A41 Other septicaemia
0.700 0.300 0.000
B99 Other and unspecified infectious diseases
0.700 0.300 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.700 0.300 0.000
C15.5 Lower third of oesophagus
0.698 0.302 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.698 0.302 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.698 0.302 0.000
K31.6 Fistula of stomach and duodenum
0.697 0.302 0.000
K31.3 Pylorospasm, not elsewhere classified
0.697 0.302 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.697 0.302 0.000
K31.0 Acute dilatation of stomach
0.697 0.302 0.000
K52.3 Indeterminate colitis
0.697 0.303 0.000
M86-M90 Other osteopathies
0.697 0.303 0.000
N18.8 Other chronic renal failure
0.696 0.304 0.000
N18.1 Chronic kidney disease, stage 1
0.696 0.304 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.696 0.304 0.000
K22.0 Achalasia of cardia
0.696 0.304 0.000
L85 Other epidermal thickening
0.696 0.304 0.000
S00.4 Superficial injury of ear
0.695 0.305 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.695 0.305 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.695 0.305 0.000
N18.2 Chronic kidney disease, stage 2
0.694 0.306 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.692 0.308 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.691 0.309 0.000
S60-S69 Injuries to the wrist and hand
0.691 0.309 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.691 0.309 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.690 0.310 0.000
F70-F79 Mental retardation
0.690 0.310 0.000
A40.8 Other streptococcal septicaemia
0.690 0.310 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.690 0.310 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.689 0.311 0.000
N18.4 Chronic kidney disease, stage 4
0.688 0.312 0.000
D80-D89 Certain disorders involving the immune mechanism
0.687 0.313 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.686 0.313 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.686 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.686 0.313 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.686 0.314 0.000
T81.9 Unspecified complication of procedure
0.686 0.314 0.000
K20 Oesophagitis
0.686 0.314 0.000
C22.1 Intrahepatic bile duct carcinoma
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
Q80-Q89 Other congenital malformations
0.684 0.316 0.000
L71 Rosacea
0.684 0.316 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.684 0.316 0.000
T87 Complications peculiar to reattachment and amputation
0.680 0.319 0.000
C77.1 Intrathoracic lymph nodes
0.680 0.319 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.680 0.320 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.680 0.320 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.680 0.320 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
T36 Poisoning by systemic antibiotics
0.680 0.320 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.680 0.320 0.000
F01 Vascular dementia
0.679 0.321 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.679 0.321 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.679 0.321 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.679 0.321 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.679 0.321 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.678 0.321 0.000
T40.2 Other opioids
0.678 0.322 0.000
S10-S19 Injuries to the neck
0.678 0.322 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.677 0.323 0.000
T85.2 Mechanical complication of intraocular lens
0.675 0.325 0.000
K27 Peptic ulcer, site unspecified
0.674 0.326 0.000
N00-N08 Glomerular diseases
0.671 0.329 0.000
F22 Persistent delusional disorders
0.670 0.330 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.670 0.330 0.000
S90-S99 Injuries to the ankle and foot
0.670 0.330 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.669 0.331 0.000
S29 Other and unspecified injuries of thorax
0.668 0.332 0.000
M22 Disorders of patella
0.668 0.332 0.000
N23 Unspecified renal colic
0.667 0.333 0.000
T82.3 Mechanical complication of other vascular grafts
0.666 0.334 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.666 0.334 0.000
A80-A89 Viral infections of the central nervous system
0.663 0.337 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.662 0.338 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.662 0.338 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.662 0.338 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.662 0.338 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.662 0.338 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.662 0.338 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.662 0.338 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.661 0.339 0.000
L10-L14 Bullous disorders
0.661 0.339 0.000
F28 Other nonorganic psychotic disorders
0.660 0.340 0.000
F24 Induced delusional disorder
0.660 0.340 0.000
F21 Schizotypal disorder
0.660 0.340 0.000
C78.2 Secondary malignant neoplasm of pleura
0.659 0.341 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.659 0.341 0.000
T51 Toxic effect of alcohol
0.659 0.341 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.659 0.341 0.000
L89.2 Stage III decubitus ulcer
0.658 0.342 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.658 0.342 0.000
M65 Synovitis and tenosynovitis
0.658 0.342 0.000
N25-N29 Other disorders of kidney and ureter
0.657 0.342 0.000
C81 Hodgkin's disease
0.657 0.343 0.000
C77.5 Intrapelvic lymph nodes
0.657 0.343 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.656 0.343 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.656 0.343 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.656 0.343 0.000
M91-M94 Chondropathies
0.656 0.344 0.000
F29 Unspecified nonorganic psychosis
0.654 0.345 0.000
F99-F99 Unspecified mental disorder
0.654 0.346 0.000
D61 Other aplastic anaemias
0.654 0.346 0.000
K31.5 Obstruction of duodenum
0.654 0.346 0.000
K90-K93 Other diseases of the digestive system
0.653 0.347 0.000
C91.1 Chronic lymphocytic leukaemia
0.653 0.347 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.653 0.347 0.000
M23 Internal derangement of knee
0.653 0.347 0.000
M21 Other acquired deformities of limbs
0.652 0.348 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.651 0.349 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.650 0.350 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.650 0.350 0.000
F20.0 Paranoid schizophrenia
0.650 0.350 0.000
C15.4 Middle third of oesophagus
0.648 0.352 0.000
B35-B49 Mycoses
0.647 0.353 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.647 0.353 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.646 0.354 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.646 0.354 0.000
T83.2 Mechanical complication of graft of urinary organ
0.646 0.354 0.000
N13.8 Other obstructive and reflux uropathy
0.646 0.354 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.646 0.354 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.644 0.356 0.000
C18.6 Descending colon
0.644 0.356 0.000
T40.4 Other synthetic narcotics
0.644 0.356 0.000
M00-M03 Infectious arthropathies
0.644 0.356 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.644 0.356 0.000
F02 Dementia in other diseases classified elsewhere
0.644 0.356 0.000
F09 Unspecified organic or symptomatic mental disorder
0.644 0.356 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.644 0.356 0.000
S02.6 Fracture of mandible
0.644 0.356 0.000
C77.3 Axillary and upper limb lymph nodes
0.643 0.357 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.643 0.357 0.000
N17 Acute renal failure
0.642 0.358 0.000
N83.1 Corpus luteum cyst
0.642 0.358 0.000
L84 Corns and callosities
0.641 0.358 0.000
L50-L54 Urticaria and erythema
0.641 0.358 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.641 0.359 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.641 0.359 0.000
B06 Rubella [German measles]
0.641 0.359 0.000
B05 Measles
0.641 0.359 0.000
B01 Varicella [chickenpox]
0.641 0.359 0.000
B00 Herpesviral [herpes simplex] infections
0.641 0.359 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.641 0.359 0.000
B04 Monkeypox
0.641 0.359 0.000
B03 Smallpox
0.641 0.359 0.000
T86 Failure and rejection of transplanted organs and tissues
0.640 0.360 0.000
B02 Zoster [herpes zoster]
0.639 0.361 0.000
K65-K67 Diseases of peritoneum
0.639 0.361 0.000
C60-C63 Malignant neoplasms of male genital organs
0.638 0.362 0.000
T43.9 Psychotropic drug, unspecified
0.637 0.363 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
T43.6 Psychostimulants with abuse potential
0.637 0.363 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.637 0.363 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.637 0.363 0.000
N98 Complications associated with artificial fertilisation
0.637 0.363 0.000
N91 Absent, scanty and rare menstruation
0.637 0.363 0.000
N96 Habitual aborter
0.637 0.363 0.000
N89 Other noninflammatory disorders of vagina
0.636 0.364 0.000
L82 Seborrhoeic keratosis
0.636 0.364 0.000
D00-D09 In situ neoplasms
0.635 0.365 0.000
C15.8 Overlapping lesion of oesophagus
0.635 0.365 0.000
C15.3 Upper third of oesophagus
0.635 0.365 0.000
C15.2 Abdominal part of oesophagus
0.635 0.365 0.000
C15.1 Thoracic part of oesophagus
0.635 0.365 0.000
C15.0 Cervical part of oesophagus
0.635 0.365 0.000
M35 Other systemic involvement of connective tissue
0.635 0.365 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.635 0.365 0.000
N92 Excessive, frequent and irregular menstruation
0.635 0.365 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.634 0.365 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.634 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.634 0.366 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.634 0.366 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.634 0.366 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.634 0.366 0.000
L91 Hypertrophic disorders of skin
0.633 0.367 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.633 0.367 0.000
S50-S59 Injuries to the elbow and forearm
0.633 0.367 0.000
C79.6 Secondary malignant neoplasm of ovary
0.633 0.367 0.000
N94.5 Secondary dysmenorrhoea
0.633 0.367 0.000
N94.2 Vaginismus
0.633 0.367 0.000
N94.0 Mittelschmerz
0.633 0.367 0.000
U80.1 Methicillin resistant agent
0.633 0.367 0.000
N11 Chronic tubulo-interstitial nephritis
0.633 0.367 0.000
L80 Vitiligo
0.632 0.367 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.632 0.368 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.632 0.368 0.000
D51.2 Transcobalamin II deficiency
0.632 0.368 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.632 0.368 0.000
C71 Malignant neoplasm of brain
0.632 0.368 0.000
C51-C58 Malignant neoplasms of female genital organs
0.631 0.369 0.000
D64.9 Anaemia, unspecified
0.630 0.370 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.629 0.370 0.000
S27 Injury of other and unspecified intrathoracic organs
0.629 0.371 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.627 0.373 0.000
F52.2 Failure of genital response
0.627 0.373 0.000
F25.1 Schizoaffective disorder, depressive type
0.626 0.374 0.000
L93 Lupus erythematosus
0.626 0.374 0.000
L71.9 Rosacea, unspecified
0.625 0.375 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.625 0.375 0.000
S62 Fracture at wrist and hand level
0.624 0.376 0.000
T16 Foreign body in ear
0.624 0.376 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.624 0.376 0.000
L83 Acanthosis nigricans
0.623 0.376 0.000
T40.6 Other and unspecified narcotics
0.623 0.377 0.000
D52 Folate deficiency anaemia
0.622 0.377 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.622 0.378 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.622 0.378 0.000
N88.3 Incompetence of cervix uteri
0.622 0.378 0.000
N88.1 Old laceration of cervix uteri
0.622 0.378 0.000
N88.0 Leukoplakia of cervix uteri
0.622 0.378 0.000
A48 Other bacterial diseases, not elsewhere classified
0.622 0.378 0.000
A44 Bartonellosis
0.622 0.378 0.000
A43 Nocardiosis
0.622 0.378 0.000
A42 Actinomycosis
0.622 0.378 0.000
A39 Meningococcal infection
0.622 0.378 0.000
A37 Whooping cough
0.622 0.378 0.000
A36 Diphtheria
0.622 0.378 0.000
A32 Listeriosis
0.622 0.378 0.000
A31 Infection due to other mycobacteria
0.622 0.378 0.000
A30 Leprosy [Hansen's disease]
0.622 0.378 0.000
A38 Scarlet fever
0.622 0.378 0.000
A35 Other tetanus
0.622 0.378 0.000
A34 Obstetrical tetanus
0.622 0.378 0.000
A33 Tetanus neonatorum
0.622 0.378 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.622 0.378 0.000
M22.8 Other disorders of patella
0.621 0.378 0.000
T59 Toxic effect of other gases, fumes and vapours
0.620 0.379 0.000
K31.4 Gastric diverticulum
0.620 0.380 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.620 0.380 0.000
S70-S79 Injuries to the hip and thigh
0.620 0.380 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.619 0.381 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.619 0.381 0.000
F25.9 Schizoaffective disorder, unspecified
0.618 0.382 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.617 0.382 0.000
C69 Malignant neoplasm of eye and adnexa
0.616 0.384 0.000
T31.0 Burns involving less than 10% of body surface
0.616 0.384 0.000
N82 Fistulae involving female genital tract
0.616 0.384 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.615 0.385 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.615 0.385 0.000
Chapter VI Diseases of the nervous system
0.614 0.386 0.000
L25 Unspecified contact dermatitis
0.613 0.387 0.000
L24 Irritant contact dermatitis
0.613 0.387 0.000
L23 Allergic contact dermatitis
0.613 0.387 0.000
L21 Seborrhoeic dermatitis
0.613 0.387 0.000
L20 Atopic dermatitis
0.613 0.387 0.000
L26 Exfoliative dermatitis
0.613 0.387 0.000
L22 Diaper [napkin] dermatitis
0.613 0.387 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.613 0.387 0.000
M70-M79 Other soft tissue disorders
0.613 0.387 0.000
S02.5 Fracture of tooth
0.612 0.388 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.611 0.389 0.000
N87 Dysplasia of cervix uteri
0.610 0.390 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.610 0.390 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.610 0.390 0.000
N15 Other renal tubulo-interstitial diseases
0.610 0.390 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.610 0.390 0.000
L29 Pruritus
0.610 0.390 0.000
L85.9 Epidermal thickening, unspecified
0.609 0.391 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.609 0.391 0.000
N97 Female infertility
0.609 0.391 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.608 0.392 0.000
N10 Acute tubulo-interstitial nephritis
0.607 0.393 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.607 0.393 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.607 0.393 0.000
L94 Other localised connective tissue disorders
0.607 0.393 0.000
L87 Transepidermal elimination disorders
0.607 0.393 0.000
L88 Pyoderma gangrenosum
0.607 0.393 0.000
L86 Keratoderma in diseases classified elsewhere
0.607 0.393 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.606 0.394 0.000
M60-M63 Disorders of muscles
0.606 0.394 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.606 0.394 0.000
H80-H83 Diseases of inner ear
0.605 0.395 0.000
C16 Malignant neoplasm of stomach
0.604 0.395 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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