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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74360883
log Bayes Factor = 1.78422
Chromosome 11   position 45,550,753  (GRCh37) Explore rs74360883 on Ensembl!
Variant rs74360883 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.021 0.979
I25 Chronic ischaemic heart disease
0.000 0.025 0.975
I20 Angina pectoris
0.000 0.031 0.969
Chapter IX Diseases of the circulatory system
0.000 0.033 0.967
I30-I52 Other forms of heart disease
0.000 0.038 0.962
I50 Heart failure
0.000 0.039 0.961
I50.1 Left ventricular failure
0.000 0.041 0.959
I20.0 Unstable angina
0.000 0.045 0.955
I25.1 Atherosclerotic heart disease
0.000 0.060 0.940
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.081 0.919
I10-I15 Hypertensive diseases
0.000 0.082 0.918
I10 Essential (primary) hypertension
0.000 0.117 0.883
I21 Acute myocardial infarction
0.000 0.157 0.843
I51 Complications and ill-defined descriptions of heart disease
0.000 0.164 0.836
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.187 0.813
I20.9 Angina pectoris, unspecified
0.000 0.195 0.805
I25.2 Old myocardial infarction
0.000 0.211 0.789
I50.0 Congestive heart failure
0.000 0.219 0.781
I60-I69 Cerebrovascular diseases
0.000 0.221 0.779
I22 Subsequent myocardial infarction
0.000 0.244 0.756
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.249 0.751
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.257 0.743
I51.8 Other ill-defined heart diseases
0.000 0.259 0.741
I20.8 Other forms of angina pectoris
0.000 0.265 0.735
I38 Endocarditis, valve unspecified
0.000 0.265 0.735
I35 Nonrheumatic aortic valve disorders
0.000 0.274 0.726
I34 Nonrheumatic mitral valve disorders
0.000 0.281 0.719
I23 Certain current complications following acute myocardial infarction
0.000 0.298 0.702
I42 Cardiomyopathy
0.000 0.299 0.700
I25.6 Silent myocardial ischaemia
0.000 0.301 0.699
I25.5 Ischaemic cardiomyopathy
0.000 0.301 0.699
I25.4 Coronary artery aneurysm
0.000 0.301 0.699
I25.3 Aneurysm of heart
0.000 0.301 0.699
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.301 0.699
I49 Other cardiac arrhythmias
0.000 0.304 0.696
I20.1 Angina pectoris with documented spasm
0.000 0.305 0.695
I00-I02 Acute rheumatic fever
0.000 0.307 0.693
I31 Other diseases of pericardium
0.000 0.307 0.693
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.309 0.691
I52 Other heart disorders in diseases classified elsewhere
0.000 0.310 0.690
I48 Atrial fibrillation and flutter
0.000 0.310 0.690
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.310 0.690
I41 Myocarditis in diseases classified elsewhere
0.000 0.310 0.690
I40 Acute myocarditis
0.000 0.310 0.690
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.310 0.690
I37 Pulmonary valve disorders
0.000 0.310 0.690
I36 Nonrheumatic tricuspid valve disorders
0.000 0.310 0.690
I33 Acute and subacute endocarditis
0.000 0.310 0.690
I32 Pericarditis in diseases classified elsewhere
0.000 0.310 0.690
I30 Acute pericarditis
0.000 0.310 0.690
I15 Secondary hypertension
0.000 0.342 0.658
I13 Hypertensive heart and renal disease
0.000 0.342 0.658
I11 Hypertensive heart disease
0.000 0.342 0.658
I12 Hypertensive renal disease
0.000 0.348 0.651
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.350 0.650
I21.9 Acute myocardial infarction, unspecified
0.000 0.353 0.647
I24 Other acute ischaemic heart diseases
0.000 0.356 0.644
I51.9 Heart disease, unspecified
0.000 0.356 0.644
I46 Cardiac arrest
0.000 0.363 0.637
I65.2 Occlusion and stenosis of carotid artery
0.000 0.371 0.629
I61 Intracerebral haemorrhage
0.000 0.375 0.625
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.396 0.604
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.396 0.604
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.396 0.604
I51.6 Cardiovascular disease, unspecified
0.000 0.401 0.599
I51.5 Myocardial degeneration
0.000 0.401 0.599
I51.4 Myocarditis, unspecified
0.000 0.401 0.599
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.401 0.599
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.401 0.599
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.401 0.599
I51.0 Cardiac septal defect, acquired
0.000 0.401 0.599
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.403 0.597
I71 Aortic aneurysm and dissection
0.000 0.406 0.594
I50.9 Heart failure, unspecified
0.000 0.414 0.585
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.423 0.577
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.428 0.572
I21.4 Acute subendocardial myocardial infarction
0.000 0.429 0.571
I05-I09 Chronic rheumatic heart diseases
0.000 0.432 0.567
I44 Atrioventricular and left bundle-branch block
0.000 0.434 0.566
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.435 0.565
I77 Other disorders of arteries and arterioles
0.000 0.436 0.564
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.442 0.558
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.442 0.558
I51.7 Cardiomegaly
0.000 0.443 0.557
I34.1 Mitral (valve) prolapse
0.000 0.445 0.555
I60 Subarachnoid haemorrhage
0.000 0.447 0.553
I31.9 Disease of pericardium, unspecified
0.000 0.451 0.549
I49.3 Ventricular premature depolarisation
0.000 0.453 0.547
I42.9 Cardiomyopathy, unspecified
0.000 0.454 0.546
I22.8 Subsequent myocardial infarction of other sites
0.000 0.458 0.542
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.458 0.542
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.458 0.542
I35.0 Aortic (valve) stenosis
0.000 0.458 0.542
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.459 0.541
I69 Sequelae of cerebrovascular disease
0.000 0.462 0.538
I45 Other conduction disorders
0.000 0.467 0.533
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.467 0.533
I72 Other aneurysm
0.000 0.467 0.533
I78 Diseases of capillaries
0.000 0.467 0.533
I62 Other nontraumatic intracranial haemorrhage
0.000 0.468 0.532
I70 Atherosclerosis
0.000 0.477 0.523
I35.9 Aortic valve disorder, unspecified
0.000 0.479 0.521
I35.8 Other aortic valve disorders
0.000 0.479 0.521
I35.1 Aortic (valve) insufficiency
0.000 0.483 0.517
I49.5 Sick sinus syndrome
0.000 0.483 0.517
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.484 0.516
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.484 0.515
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.484 0.515
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.484 0.515
I74 Arterial embolism and thrombosis
0.000 0.487 0.513
I47 Paroxysmal tachycardia
0.000 0.487 0.513
I27 Other pulmonary heart diseases
0.000 0.489 0.511
I73 Other peripheral vascular diseases
0.000 0.490 0.510
I49.8 Other specified cardiac arrhythmias
0.000 0.492 0.508
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.494 0.506
I23.8 Other current complications following acute myocardial infarction
0.000 0.497 0.503
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.497 0.503
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.497 0.503
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.497 0.503
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.497 0.503
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.497 0.503
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.497 0.503
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.497 0.503
I34.0 Mitral (valve) insufficiency
0.000 0.497 0.503
I42.8 Other cardiomyopathies
0.000 0.498 0.502
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.498 0.502
I42.6 Alcoholic cardiomyopathy
0.000 0.498 0.502
I42.5 Other restrictive cardiomyopathy
0.000 0.498 0.502
I42.4 Endocardial fibroelastosis
0.000 0.498 0.502
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.498 0.502
I42.2 Other hypertrophic cardiomyopathy
0.000 0.498 0.502
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.498 0.502
I49.2 Junctional premature depolarisation
0.000 0.501 0.499
I49.1 Atrial premature depolarisation
0.000 0.501 0.499
I02 Rheumatic chorea
0.000 0.503 0.497
I01 Rheumatic fever with heart involvement
0.000 0.503 0.497
I00 Rheumatic fever without mention of heart involvement
0.000 0.503 0.497
I31.8 Other specified diseases of pericardium
0.000 0.503 0.497
I31.2 Haemopericardium, not elsewhere classified
0.000 0.503 0.497
I31.1 Chronic constrictive pericarditis
0.000 0.503 0.497
I31.0 Chronic adhesive pericarditis
0.000 0.503 0.497
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.504 0.496
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.504 0.496
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.504 0.496
I65.1 Occlusion and stenosis of basilar artery
0.000 0.504 0.496
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.504 0.496
I63 Cerebral infarction
0.000 0.505 0.495
I30.9 Acute pericarditis, unspecified
0.000 0.505 0.495
I30.8 Other forms of acute pericarditis
0.000 0.505 0.495
I30.1 Infective pericarditis
0.000 0.505 0.495
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.505 0.495
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.505 0.495
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.505 0.495
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.505 0.495
I33.9 Acute endocarditis, unspecified
0.000 0.505 0.495
I33.0 Acute and subacute infective endocarditis
0.000 0.505 0.495
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.505 0.495
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.505 0.495
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.505 0.495
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.505 0.495
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.505 0.495
I37.9 Pulmonary valve disorder, unspecified
0.000 0.505 0.495
I37.8 Other pulmonary valve disorders
0.000 0.505 0.495
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.505 0.495
I37.1 Pulmonary valve insufficiency
0.000 0.505 0.495
I37.0 Pulmonary valve stenosis
0.000 0.505 0.495
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.505 0.495
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.505 0.495
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.505 0.495
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.505 0.495
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.505 0.495
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.505 0.495
I40.9 Acute myocarditis, unspecified
0.000 0.505 0.495
I40.8 Other acute myocarditis
0.000 0.505 0.495
I40.1 Isolated myocarditis
0.000 0.505 0.495
I40.0 Infective myocarditis
0.000 0.505 0.495
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.505 0.495
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.505 0.495
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.505 0.495
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.505 0.495
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.505 0.495
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.505 0.495
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.505 0.495
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.505 0.495
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.505 0.495
I48.4 Atypical atrial flutter
0.000 0.505 0.495
I48.3 Typical atrial flutter
0.000 0.505 0.495
I48.2 Chronic atrial fibrillation
0.000 0.505 0.495
I48.1 Persistent atrial fibrillation
0.000 0.505 0.495
I48.0 Paroxysmal atrial fibrillation
0.000 0.505 0.495
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.505 0.495
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.505 0.495
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.505 0.495
I49.4 Other and unspecified premature depolarisation
0.000 0.514 0.486
I49.0 Ventricular fibrillation and flutter
0.000 0.519 0.481
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.528 0.472
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.528 0.472
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.528 0.472
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.528 0.472
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.528 0.472
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.528 0.472
I15.9 Seconday hypertension, unspecified
0.000 0.528 0.472
I15.8 Other secondary hypertension
0.000 0.528 0.472
I15.2 Hypertension secondary to endocrine disorders
0.000 0.528 0.472
I15.1 Hypertension secondary to other renal disorders
0.000 0.528 0.472
I15.0 Renovascular hypertension
0.000 0.528 0.472
I12.9 Hypertensive renal disease without renal failure
0.000 0.533 0.467
I28 Other diseases of pulmonary vessels
0.000 0.534 0.466
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.535 0.465
I67 Other cerebrovascular diseases
0.000 0.535 0.465
I24.1 Dressler's syndrome
0.000 0.538 0.462
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.538 0.462
I12.0 Hypertensive renal disease with renal failure
0.000 0.539 0.461
I42.0 Dilated cardiomyopathy
0.000 0.540 0.460
I46.1 Sudden cardiac death, so described
0.000 0.543 0.457
I61.8 Other intracerebral haemorrhage
0.000 0.551 0.448
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.551 0.448
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.551 0.448
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.551 0.448
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.551 0.448
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.551 0.448
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.551 0.448
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.551 0.448
I49.9 Cardiac arrhythmia, unspecified
0.000 0.554 0.446
I46.0 Cardiac arrest with successful resuscitation
0.000 0.556 0.444
I77.1 Stricture of artery
0.000 0.560 0.440
I31.3 Pericardial effusion (noninflammatory)
0.000 0.571 0.429
I78.1 Naevus, nonneoplastic
0.000 0.573 0.427
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.574 0.426
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.574 0.426
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.574 0.426
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.574 0.426
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.574 0.426
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.574 0.426
I71.0 Dissection of aorta [any part]
0.000 0.574 0.426
I46.9 Cardiac arrest, unspecified
0.000 0.581 0.419
I27.0 Primary pulmonary hypertension
0.000 0.582 0.418
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.586 0.414
I99 Other and unspecified disorders of circulatory system
0.000 0.586 0.414
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.591 0.409
I44.1 Atrioventricular block, second degree
0.000 0.592 0.408
I09 Other rheumatic heart diseases
0.000 0.593 0.407
I06 Rheumatic aortic valve diseases
0.000 0.593 0.407
I44.6 Other and unspecified fascicular block
0.000 0.594 0.406
I44.5 Left posterior fascicular block
0.000 0.594 0.406
I44.4 Left anterior fascicular block
0.000 0.594 0.406
I44.3 Other and unspecified atrioventricular block
0.000 0.594 0.406
I07 Rheumatic tricuspid valve diseases
0.000 0.594 0.406
I73.0 Raynaud's syndrome
0.000 0.594 0.406
I77.8 Other specified disorders of arteries and arterioles
0.000 0.595 0.405
I77.6 Arteritis, unspecified
0.000 0.595 0.405
I77.5 Necrosis of artery
0.000 0.595 0.405
I77.4 Coeliac artery compression syndrome
0.000 0.595 0.405
I77.3 Arterial fibromuscular dysplasia
0.000 0.595 0.405
I77.2 Rupture of artery
0.000 0.595 0.405
I77.0 Arteriovenous fistula, acquired
0.000 0.595 0.405
I44.7 Left bundle-branch block, unspecified
0.000 0.597 0.403
I24.8 Other forms of acute ischaemic heart disease
0.000 0.599 0.401
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.599 0.400
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.599 0.400
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.599 0.400
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.599 0.400
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.599 0.400
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.599 0.400
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.599 0.400
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.599 0.400
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.599 0.400
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.599 0.400
I68.0 Cerebral amyloid angiopathy
0.000 0.599 0.400
I08 Multiple valve diseases
0.000 0.600 0.400
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.600 0.400
I69.3 Sequelae of cerebral infarction
0.000 0.603 0.397
I60.8 Other subarachnoid haemorrhage
0.000 0.603 0.396
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.603 0.396
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.603 0.396
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.603 0.396
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.603 0.396
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.603 0.396
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.603 0.396
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.603 0.396
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.603 0.396
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.609 0.391
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.609 0.391
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.614 0.386
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.614 0.386
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.614 0.386
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.614 0.386
I45.8 Other specified conduction disorders
0.000 0.617 0.382
I45.5 Other specified heart block
0.000 0.617 0.382
I45.4 Nonspecific intraventricular block
0.000 0.617 0.382
I45.3 Trifascicular block
0.000 0.617 0.382
I45.2 Bifascicular block
0.000 0.617 0.382
I45.0 Right fascicular block
0.000 0.617 0.382
I72.9 Aneurysm of unspecified site
0.000 0.618 0.382
I72.8 Aneurysm of other specified arteries
0.000 0.618 0.382
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.618 0.382
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.618 0.382
I72.4 Aneurysm of artery of lower extremity
0.000 0.618 0.382
I72.3 Aneurysm of iliac artery
0.000 0.618 0.382
I72.2 Aneurysm of renal artery
0.000 0.618 0.382
I72.1 Aneurysm of artery of upper extremity
0.000 0.618 0.382
I72.0 Aneurysm of carotid artery
0.000 0.618 0.382
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.618 0.382
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.618 0.382
I79.1 Aortitis in diseases classified elsewhere
0.000 0.618 0.382
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.618 0.382
I78.9 Disease of capillaries, unspecified
0.000 0.618 0.382
I78.8 Other diseases of capillaries
0.000 0.618 0.382
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.618 0.382
I62.1 Nontraumatic extradural haemorrhage
0.000 0.618 0.382
I70.9 Generalised and unspecified atherosclerosis
0.000 0.625 0.375
I70.8 Atherosclerosis of other arteries
0.000 0.625 0.375
I70.1 Atherosclerosis of renal artery
0.000 0.625 0.375
I70.0 Atherosclerosis of aorta
0.000 0.625 0.375
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.632 0.368
I74.8 Embolism and thrombosis of other arteries
0.000 0.632 0.368
I74.5 Embolism and thrombosis of iliac artery
0.000 0.632 0.368
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.632 0.368
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.632 0.368
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.632 0.368
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.632 0.368
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.632 0.368
I47.0 Reentry ventricular arrhythmia
0.000 0.632 0.368
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.632 0.368
I27.9 Pulmonary heart disease, unspecified
0.000 0.633 0.367
I27.8 Other specified pulmonary heart diseases
0.000 0.633 0.367
I27.1 Kyphoscoliotic heart disease
0.000 0.633 0.367
I73.8 Other specified peripheral vascular diseases
0.000 0.634 0.366
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.634 0.366
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.635 0.365
I95 Hypotension
0.000 0.635 0.364
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.638 0.362
I44.0 Atrioventricular block, first degree
0.000 0.639 0.361
I27.2 Other secondary pulmonary hypertension
0.000 0.643 0.357
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.643 0.356
I01.8 Other acute rheumatic heart disease
0.000 0.643 0.356
I01.2 Acute rheumatic myocarditis
0.000 0.643 0.356
I01.1 Acute rheumatic endocarditis
0.000 0.643 0.356
I01.0 Acute rheumatic pericarditis
0.000 0.643 0.356
I02.9 Rheumatic chorea without heart involvement
0.000 0.643 0.356
I02.0 Rheumatic chorea with heart involvement
0.000 0.643 0.356
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.644 0.355
I63.8 Other cerebral infarction
0.000 0.645 0.355
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.645 0.355
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.645 0.355
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.645 0.355
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.645 0.355
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.645 0.355
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.645 0.355
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.648 0.352
I45.9 Conduction disorder, unspecified
0.000 0.649 0.350
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.651 0.348
I26 Pulmonary embolism
0.000 0.652 0.348
I45.1 Other and unspecified right bundle-branch block
0.000 0.653 0.346
I44.2 Atrioventricular block, complete
0.000 0.654 0.346
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.666 0.334
I28.8 Other specified diseases of pulmonary vessels
0.000 0.666 0.334
I28.1 Aneurysm of pulmonary artery
0.000 0.666 0.334
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.666 0.334
I80 Phlebitis and thrombophlebitis
0.000 0.666 0.333
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.666 0.333
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.666 0.333
I67.5 Moyamoya disease
0.000 0.666 0.333
I67.4 Hypertensive encephalopathy
0.000 0.666 0.333
I67.3 Progressive vascular leukoencephalopathy
0.000 0.666 0.333
I67.2 Cerebral atherosclerosis
0.000 0.666 0.333
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.666 0.333
I45.6 Preexcitation syndrome
0.000 0.672 0.328
I47.2 Ventricular tachycardia
0.000 0.674 0.325
I67.1 Cerebral aneurysm, nonruptured
0.000 0.677 0.322
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.683 0.317
I08.0 Disorders of both mitral and aortic valves
0.000 0.689 0.311
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.695 0.305
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.696 0.303
I67.8 Other specified cerebrovascular diseases
0.000 0.697 0.303
I85 Oesophageal varices
0.000 0.700 0.300
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.703 0.297
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.703 0.297
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.703 0.297
I97.1 Other functional disturbances following cardiac surgery
0.000 0.703 0.297
I97.0 Postcardiotomy syndrome
0.000 0.703 0.297
I05 Rheumatic mitral valve diseases
0.001 0.704 0.295
I67.9 Cerebrovascular disease, unspecified
0.000 0.704 0.296
I88 Nonspecific lymphadenitis
0.000 0.706 0.293
I86 Varicose veins of other sites
0.000 0.706 0.293
I82 Other venous embolism and thrombosis
0.000 0.706 0.293
I81 Portal vein thrombosis
0.000 0.706 0.293
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.708 0.292
I06.8 Other rheumatic aortic valve diseases
0.000 0.708 0.292
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.708 0.292
I06.1 Rheumatic aortic insufficiency
0.000 0.708 0.292
I06.0 Rheumatic aortic stenosis
0.000 0.708 0.292
I09.9 Rheumatic heart disease, unspecified
0.000 0.708 0.292
I09.8 Other specified rheumatic heart diseases
0.000 0.708 0.292
I09.2 Chronic rheumatic pericarditis
0.000 0.708 0.292
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.708 0.292
I09.0 Rheumatic myocarditis
0.000 0.708 0.292
I07.9 Tricuspid valve disease, unspecified
0.000 0.709 0.291
I07.8 Other tricuspid valve diseases
0.000 0.709 0.291
I07.2 Tricuspid stenosis with insufficiency
0.000 0.709 0.291
I07.0 Tricuspid stenosis
0.000 0.709 0.291
I07.1 Tricuspid insufficiency
0.000 0.710 0.290
I08.9 Multiple valve disease, unspecified
0.000 0.713 0.287
I08.8 Other multiple valve diseases
0.000 0.713 0.287
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.713 0.287
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.713 0.287
I73.9 Peripheral vascular disease, unspecified
0.000 0.721 0.278
I95.9 Hypotension, unspecified
0.000 0.724 0.276
I63.9 Cerebral infarction, unspecified
0.000 0.728 0.272
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.731 0.269
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.731 0.269
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.731 0.269
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.731 0.269
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.731 0.269
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.731 0.269
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.731 0.269
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.731 0.269
I47.1 Supraventricular tachycardia
0.000 0.736 0.263
I87 Other disorders of veins
0.000 0.737 0.262
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.738 0.261
I95.8 Other hypotension
0.000 0.738 0.261
I95.2 Hypotension due to drugs
0.000 0.738 0.261
I95.0 Idiopathic hypotension
0.000 0.738 0.261
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.740 0.259
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.740 0.259
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.740 0.259
I98.0 Cardiovascular syphilis
0.000 0.740 0.259
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.748 0.251
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.750 0.250
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.753 0.246
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.757 0.243
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.761 0.239
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.767 0.233
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.772 0.228
I89.0 Lymphoedema, not elsewhere classified
0.000 0.772 0.228
I83 Varicose veins of lower extremities
0.000 0.774 0.226
I85.9 Oesophageal varices without bleeding
0.000 0.778 0.222
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.782 0.218
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.782 0.218
I89.1 Lymphangitis
0.000 0.782 0.218
I85.0 Oesophageal varices with bleeding
0.000 0.784 0.215
I05.8 Other mitral valve diseases
0.001 0.788 0.212
I05.2 Mitral stenosis with insufficiency
0.001 0.788 0.212
I05.1 Rheumatic mitral insufficiency
0.001 0.788 0.212
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.789 0.210
I82.8 Embolism and thrombosis of other specified veins
0.000 0.789 0.210
I82.3 Embolism and thrombosis of renal vein
0.000 0.789 0.210
I82.2 Embolism and thrombosis of vena cava
0.000 0.789 0.210
I82.1 Thrombophlebitis migrans
0.000 0.789 0.210
I82.0 Budd-Chiari syndrome
0.000 0.789 0.210
I86.8 Varicose veins of other specified sites
0.000 0.789 0.210
I86.4 Gastric varices
0.000 0.789 0.210
I86.3 Vulval varices
0.000 0.789 0.210
I86.2 Pelvic varices
0.000 0.789 0.210
I86.1 Scrotal varices
0.000 0.789 0.210
I86.0 Sublingual varices
0.000 0.789 0.210
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.789 0.210
I88.8 Other nonspecific lymphadenitis
0.000 0.789 0.210
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.789 0.210
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.789 0.210
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.792 0.207
I87.9 Disorder of vein, unspecified
0.000 0.811 0.188
I87.8 Other specified disorders of veins
0.000 0.811 0.188
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.811 0.188
I87.0 Postphlebitic syndrome
0.000 0.811 0.188
I95.1 Orthostatic hypotension
0.000 0.812 0.187
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.823 0.176
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.827 0.173
I05.0 Mitral stenosis
0.001 0.829 0.171
O60-O75 Complications of labour and delivery
0.166 0.834 0.000
I05.9 Mitral valve disease, unspecified
0.001 0.835 0.164
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.838 0.162
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.838 0.162
O68 Labour and delivery complicated by foetal stress [distress]
0.158 0.842 0.000
I87.1 Compression of vein
0.000 0.842 0.157
O72 Postpartum haemorrhage
0.153 0.846 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.143 0.857 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.142 0.858 0.000
O63 Long labour
0.141 0.859 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.141 0.859 0.000
O70 Perineal laceration during delivery
0.140 0.860 0.000
O72.1 Other immediate postpartum haemorrhage
0.135 0.865 0.000
O73 Retained placenta and membranes, without haemorrhage
0.134 0.866 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.132 0.867 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.868 0.132
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.131 0.869 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.130 0.870 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.130 0.870 0.000
O70.0 First degree perineal laceration during delivery
0.128 0.872 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.126 0.874 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.125 0.874 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.123 0.877 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.122 0.877 0.000
O63.1 Prolonged second stage (of labour)
0.119 0.880 0.000
O74 Complications of anaesthesia during labour and delivery
0.119 0.880 0.000
O71 Other obstetric trauma
0.119 0.880 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.119 0.880 0.000
O66 Other obstructed labour
0.119 0.880 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.119 0.880 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.119 0.880 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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