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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74399042
log Bayes Factor = 17.8814
Chromosome 1   position 16,581,325  (GRCh37) Explore rs74399042 on Ensembl!
Variant rs74399042 is part of Cluster X0015

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
R30-R39 Symptoms and signs involving the urinary system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
M25 Other joint disorders, not elsewhere classified
0.997 0.003 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
K70-K77 Diseases of liver
0.993 0.007 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.989 0.011 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.983 0.017 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.974 0.026 0.000
R50-R69 General symptoms and signs
0.972 0.028 0.000
R39 Other symptoms and signs involving the urinary system
0.972 0.028 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.970 0.030 0.000
K22 Other diseases of oesophagus
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.965 0.035 0.000
R55 Syncope and collapse
0.965 0.035 0.000
K50-K52 Noninfective enteritis and colitis
0.962 0.038 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.962 0.038 0.000
M25.5 Pain in joint
0.960 0.040 0.000
M25.7 Osteophyte
0.958 0.042 0.000
R31 Unspecified haematuria
0.957 0.043 0.000
I69 Sequelae of cerebrovascular disease
0.955 0.045 0.000
K70 Alcoholic liver disease
0.949 0.051 0.000
R39.1 Other difficulties with micturition
0.942 0.058 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.942 0.058 0.000
K50 Crohn's disease [regional enteritis]
0.941 0.059 0.000
Chapter XXI Factors influencing health status and contact with health services
0.940 0.060 0.000
D50-D53 Nutritional anaemias
0.939 0.061 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.936 0.064 0.000
S80-S89 Injuries to the knee and lower leg
0.933 0.067 0.000
I67 Other cerebrovascular diseases
0.927 0.073 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.926 0.074 0.000
F10.1 Harmful use
0.921 0.079 0.000
K31 Other diseases of stomach and duodenum
0.919 0.081 0.000
F17.1 Harmful use
0.912 0.088 0.000
G90-G99 Other disorders of the nervous system
0.912 0.088 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.912 0.088 0.000
D50 Iron deficiency anaemia
0.911 0.089 0.000
K50.9 Crohn's disease, unspecified
0.909 0.091 0.000
K75 Other inflammatory liver diseases
0.904 0.096 0.000
R35 Polyuria
0.904 0.096 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.903 0.097 0.000
R30 Pain associated with micturition
0.903 0.097 0.000
Chapter XIV Diseases of the genitourinary system
0.901 0.099 0.000
F10.0 Acute intoxication
0.900 0.100 0.000
D50.9 Iron deficiency anaemia, unspecified
0.895 0.105 0.000
K22.8 Other specified diseases of oesophagus
0.893 0.107 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.888 0.112 0.000
R47-R49 Symptoms and signs involving speech and voice
0.885 0.115 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.884 0.116 0.000
T66-T78 Other and unspecified effects of external causes
0.881 0.118 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.881 0.119 0.000
I63 Cerebral infarction
0.880 0.120 0.000
D60-D64 Aplastic and other anaemias
0.876 0.124 0.000
F17.2 Dependence syndrome
0.876 0.124 0.000
R54 Senility
0.872 0.128 0.000
K22.1 Ulcer of oesophagus
0.871 0.129 0.000
R32 Unspecified urinary incontinence
0.870 0.130 0.000
M23 Internal derangement of knee
0.865 0.135 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.865 0.135 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.863 0.137 0.000
M20 Acquired deformities of fingers and toes
0.863 0.137 0.000
I62 Other nontraumatic intracranial haemorrhage
0.863 0.137 0.000
G81 Hemiplegia
0.863 0.137 0.000
Chapter VIII Diseases of the ear and mastoid process
0.861 0.139 0.000
M25.76 Osteophyte (Lower leg)
0.860 0.140 0.000
R18 Ascites
0.858 0.142 0.000
R52 Pain, not elsewhere classified
0.857 0.143 0.000
N87 Dysplasia of cervix uteri
0.856 0.144 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.853 0.147 0.000
K31.7 Polyp of stomach and duodenum
0.853 0.147 0.000
Z50 Care involving use of rehabilitation procedures
0.846 0.154 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.846 0.154 0.000
K76 Other diseases of liver
0.845 0.155 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.843 0.157 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.842 0.158 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.841 0.159 0.000
K27 Peptic ulcer, site unspecified
0.840 0.160 0.000
N80 Endometriosis
0.839 0.161 0.000
K70.9 Alcoholic liver disease, unspecified
0.838 0.162 0.000
M25.8 Other specified joint disorders
0.838 0.162 0.000
G81.9 Hemiplegia, unspecified
0.834 0.166 0.000
R13 Dysphagia
0.833 0.167 0.000
K30 Dyspepsia
0.833 0.167 0.000
I60 Subarachnoid haemorrhage
0.832 0.168 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.832 0.168 0.000
N83.2 Other and unspecified ovarian cysts
0.829 0.171 0.000
I30-I52 Other forms of heart disease
0.829 0.171 0.000
D64 Other anaemias
0.829 0.171 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.828 0.172 0.000
F41 Other anxiety disorders
0.827 0.173 0.000
N80.0 Endometriosis of uterus
0.821 0.179 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.820 0.180 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.819 0.181 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.817 0.183 0.000
H90-H95 Other disorders of ear
0.816 0.184 0.000
K09 Cysts of oral region, not elsewhere classified
0.814 0.186 0.000
S80 Superficial injury of lower leg
0.814 0.186 0.000
M86-M90 Other osteopathies
0.814 0.186 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.814 0.186 0.000
S82 Fracture of lower leg, including ankle
0.812 0.188 0.000
R30.0 Dysuria
0.811 0.189 0.000
K12 Stomatitis and related lesions
0.808 0.192 0.000
M50-M54 Other dorsopathies
0.808 0.192 0.000
M25.9 Joint disorder, unspecified
0.807 0.193 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.807 0.193 0.000
K22.9 Disease of oesophagus, unspecified
0.806 0.194 0.000
M25.53 Pain in joint (Forearm)
0.804 0.196 0.000
N25-N29 Other disorders of kidney and ureter
0.804 0.196 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.802 0.198 0.000
N83.0 Follicular cyst of ovary
0.801 0.199 0.000
K74 Fibrosis and cirrhosis of liver
0.801 0.199 0.000
S89 Other and unspecified injuries of lower leg
0.800 0.200 0.000
M35 Other systemic involvement of connective tissue
0.799 0.201 0.000
M15-M19 Arthrosis
0.799 0.201 0.000
T78 Adverse effects, not elsewhere classified
0.798 0.202 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.796 0.204 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.796 0.204 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.796 0.204 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.795 0.205 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.795 0.205 0.000
D64.9 Anaemia, unspecified
0.795 0.205 0.000
K75.4 Autoimmune hepatitis
0.794 0.206 0.000
N30-N39 Other diseases of urinary system
0.794 0.206 0.000
M80-M85 Disorders of bone density and structure
0.793 0.207 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.791 0.209 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.791 0.209 0.000
M31 Other necrotising vasculopathies
0.789 0.211 0.000
M45-M49 Spondylopathies
0.787 0.213 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.786 0.214 0.000
M20.1 Hallux valgus (acquired)
0.786 0.214 0.000
K70.3 Alcoholic cirrhosis of liver
0.786 0.214 0.000
R63 Symptoms and signs concerning food and fluid intake
0.785 0.215 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.785 0.215 0.000
K02 Dental caries
0.784 0.216 0.000
K50.1 Crohn's disease of large intestine
0.784 0.216 0.000
F10.4 Withdrawal state with delirium
0.783 0.217 0.000
F30-F39 Mood [affective] disorders
0.781 0.219 0.000
I67.1 Cerebral aneurysm, nonruptured
0.781 0.219 0.000
K70.1 Alcoholic hepatitis
0.778 0.222 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.778 0.222 0.000
F10.2 Dependence syndrome
0.778 0.222 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.777 0.223 0.000
N87.0 Mild cervical dysplasia
0.774 0.225 0.000
M22 Disorders of patella
0.774 0.226 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.773 0.227 0.000
R47 Speech disturbances, not elsewhere classified
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.771 0.229 0.000
S60-S69 Injuries to the wrist and hand
0.768 0.232 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.768 0.232 0.000
K22.4 Dyskinesia of oesophagus
0.768 0.232 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.767 0.233 0.000
S10-S19 Injuries to the neck
0.766 0.234 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.766 0.234 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.766 0.234 0.000
K75.0 Abscess of liver
0.764 0.236 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.763 0.237 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.763 0.237 0.000
R27 Other lack of coordination
0.763 0.237 0.000
K07 Dentofacial anomalies [including malocclusion]
0.760 0.239 0.000
M21 Other acquired deformities of limbs
0.760 0.240 0.000
M34 Systemic sclerosis
0.758 0.242 0.000
I67.2 Cerebral atherosclerosis
0.756 0.244 0.000
I67.9 Cerebrovascular disease, unspecified
0.755 0.245 0.000
K70.4 Alcoholic hepatic failure
0.755 0.245 0.000
S50-S59 Injuries to the elbow and forearm
0.754 0.245 0.000
K22.5 Diverticulum of oesophagus, acquired
0.754 0.246 0.000
I69.3 Sequelae of cerebral infarction
0.754 0.246 0.000
M25.77 Osteophyte (Ankle and foot)
0.753 0.247 0.000
M25.56 Pain in joint (Lower leg)
0.753 0.247 0.000
Z50.5 Speech therapy
0.752 0.248 0.000
Z53.0 Procedure not carried out because of contraindication
0.751 0.249 0.000
Z50.0 Cardiac rehabilitation
0.751 0.249 0.000
M25.4 Effusion of joint
0.749 0.251 0.000
K31.4 Gastric diverticulum
0.749 0.251 0.000
R25 Abnormal involuntary movements
0.749 0.251 0.000
T79-T79 Certain early complications of trauma
0.749 0.251 0.000
H90 Conductive and sensorineural hearing loss
0.748 0.252 0.000
N88 Other noninflammatory disorders of cervix uteri
0.747 0.253 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.745 0.255 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.743 0.257 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.742 0.258 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.740 0.260 0.000
N83.1 Corpus luteum cyst
0.740 0.260 0.000
K22.7 Barrett's oesophagus
0.740 0.260 0.000
G93 Other disorders of brain
0.740 0.260 0.000
T82.1 Mechanical complication of cardiac electronic device
0.740 0.260 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.738 0.262 0.000
K26 Duodenal ulcer
0.737 0.263 0.000
L05 Pilonidal cyst
0.736 0.264 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.735 0.265 0.000
I44 Atrioventricular and left bundle-branch block
0.735 0.265 0.000
R61 Hyperhidrosis
0.735 0.265 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.735 0.265 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.734 0.266 0.000
D55-D59 Haemolytic anaemias
0.734 0.266 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.734 0.266 0.000
S00-S09 Injuries to the head
0.733 0.267 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.732 0.268 0.000
G20-G26 Extrapyramidal and movement disorders
0.732 0.268 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.731 0.269 0.000
K76.6 Portal hypertension
0.730 0.270 0.000
F43 Reaction to severe stress, and adjustment disorders
0.728 0.272 0.000
K04 Diseases of pulp and periapical tissues
0.728 0.272 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.726 0.274 0.000
M35.0 Sicca syndrome [Sjogren]
0.725 0.275 0.000
K31.5 Obstruction of duodenum
0.724 0.275 0.000
M20.0 Deformity of finger(s)
0.724 0.276 0.000
M40-M43 Deforming dorsopathies
0.724 0.276 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.724 0.276 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.724 0.276 0.000
Chapter VII Diseases of the eye and adnexa
0.723 0.277 0.000
Z74 Problems related to care-provider dependency
0.722 0.278 0.000
S82.8 Fractures of other parts of lower leg
0.721 0.279 0.000
G91 Hydrocephalus
0.721 0.279 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.721 0.279 0.000
K01 Embedded and impacted teeth
0.719 0.281 0.000
K14 Diseases of tongue
0.718 0.282 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
K50.0 Crohn's disease of small intestine
0.717 0.283 0.000
K12.1 Other forms of stomatitis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
R36 Urethral discharge
0.716 0.283 0.000
R34 Anuria and oliguria
0.716 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
H91 Other hearing loss
0.716 0.284 0.000
I05-I09 Chronic rheumatic heart diseases
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
Z53.9 Procedure not carried out, unspecified reason
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.715 0.285 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.715 0.285 0.000
M25.3 Other instability of joint
0.715 0.285 0.000
M25.2 Flail joint
0.715 0.285 0.000
M25.1 Fistula of joint
0.715 0.285 0.000
M25.0 Haemarthrosis
0.715 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.285 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.715 0.285 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.714 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.713 0.286 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.713 0.287 0.000
K77 Liver disorders in diseases classified elsewhere
0.712 0.288 0.000
K73 Chronic hepatitis, not elsewhere classified
0.712 0.288 0.000
K72 Hepatic failure, not elsewhere classified
0.712 0.288 0.000
K71 Toxic liver disease
0.712 0.288 0.000
I67.8 Other specified cerebrovascular diseases
0.711 0.289 0.000
L03 Cellulitis
0.711 0.289 0.000
L20-L30 Dermatitis and eczema
0.711 0.289 0.000
M16 Coxarthrosis [arthrosis of hip]
0.711 0.289 0.000
R30.9 Painful micturition, unspecified
0.710 0.290 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.709 0.291 0.000
K28 Gastrojejunal ulcer
0.709 0.291 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.709 0.291 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.709 0.291 0.000
Z46 Fitting and adjustment of other devices
0.709 0.291 0.000
F99-F99 Unspecified mental disorder
0.707 0.292 0.000
D51 Vitamin B12 deficiency anaemia
0.707 0.293 0.000
Z50.1 Other physical therapy
0.705 0.295 0.000
F10.9 Unspecified mental and behavioural disorder
0.704 0.295 0.000
F10.8 Other mental and behavioural disorders
0.704 0.295 0.000
F10.7 Residual and late-onset psychotic disorder
0.704 0.295 0.000
F10.6 Amnesic syndrome
0.704 0.295 0.000
F10.5 Psychotic disorder
0.704 0.295 0.000
M25.78 Osteophyte (Other)
0.704 0.296 0.000
S89.9 Unspecified injury of lower leg
0.704 0.296 0.000
R49 Voice disturbances
0.704 0.296 0.000
K76.8 Other specified diseases of liver
0.703 0.297 0.000
R50 Fever of unknown origin
0.701 0.299 0.000
N35 Urethral stricture
0.700 0.300 0.000
K86 Other diseases of pancreas
0.700 0.300 0.000
Chapter I Certain infectious and parasitic diseases
0.699 0.301 0.000
I61 Intracerebral haemorrhage
0.698 0.302 0.000
F41.2 Mixed anxiety and depressive disorder
0.698 0.302 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.697 0.303 0.000
R62 Lack of expected normal physiological development
0.697 0.303 0.000
R57 Shock, not elsewhere classified
0.697 0.303 0.000
R64 Cachexia
0.697 0.303 0.000
R58 Haemorrhage, not elsewhere classified
0.697 0.303 0.000
R39.2 Extrarenal uraemia
0.697 0.303 0.000
R39.0 Extravasation of urine
0.697 0.303 0.000
R68 Other general symptoms and signs
0.697 0.303 0.000
R17 Unspecified jaundice
0.697 0.303 0.000
M20.3 Other deformity of hallux (acquired)
0.696 0.304 0.000
F17.9 Unspecified mental and behavioural disorder
0.695 0.305 0.000
F17.8 Other mental and behavioural disorders
0.695 0.305 0.000
F17.7 Residual and late-onset psychotic disorder
0.695 0.305 0.000
F17.6 Amnesic syndrome
0.695 0.305 0.000
F17.5 Psychotic disorder
0.695 0.305 0.000
F17.4 Withdrawal state with delirium
0.695 0.305 0.000
F17.3 Withdrawal state
0.695 0.305 0.000
F17.0 Acute intoxication
0.695 0.305 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.695 0.305 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.695 0.305 0.000
K22.3 Perforation of oesophagus
0.694 0.306 0.000
K22.0 Achalasia of cardia
0.694 0.306 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.694 0.306 0.000
R52.2 Other chronic pain
0.694 0.306 0.000
K52 Other non-infective gastro-enteritis and colitis
0.694 0.306 0.000
K74.6 Other and unspecified cirrhosis of liver
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.692 0.308 0.000
I78 Diseases of capillaries
0.690 0.310 0.000
T78.4 Allergy, unspecified
0.690 0.310 0.000
M25.86 Other specified joint disorders (Lower leg)
0.690 0.310 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.689 0.311 0.000
T86 Failure and rejection of transplanted organs and tissues
0.689 0.311 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.689 0.311 0.000
I44.2 Atrioventricular block, complete
0.689 0.311 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.689 0.311 0.000
M25.59 Pain in joint (Site unspecified)
0.688 0.312 0.000
M25.58 Pain in joint (Other)
0.688 0.312 0.000
M25.52 Pain in joint (Upper arm)
0.688 0.312 0.000
M25.71 Osteophyte (Shoulder region)
0.688 0.312 0.000
R26 Abnormalities of gait and mobility
0.688 0.312 0.000
I42 Cardiomyopathy
0.687 0.313 0.000
M25.79 Osteophyte (Site unspecified)
0.687 0.313 0.000
M25.74 Osteophyte (Hand)
0.687 0.313 0.000
M25.73 Osteophyte (Forearm)
0.687 0.313 0.000
M25.72 Osteophyte (Upper arm)
0.687 0.313 0.000
M25.70 Osteophyte (Multiple sites)
0.687 0.313 0.000
R52.9 Pain, unspecified
0.686 0.314 0.000
F10.3 Withdrawal state
0.685 0.315 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.685 0.315 0.000
K25 Gastric ulcer
0.685 0.315 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.684 0.316 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.684 0.316 0.000
Z52 Donors of organs and tissues
0.684 0.316 0.000
N28.1 Cyst of kidney, acquired
0.683 0.317 0.000
R52.1 Chronic intractable pain
0.683 0.317 0.000
I33 Acute and subacute endocarditis
0.682 0.318 0.000
T51 Toxic effect of alcohol
0.681 0.318 0.000
K50.8 Other Crohn's disease
0.681 0.319 0.000
R63.4 Abnormal weight loss
0.681 0.319 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.681 0.319 0.000
K70.0 Alcoholic fatty liver
0.681 0.319 0.000
M16.9 Coxarthrosis, unspecified
0.679 0.321 0.000
K76.9 Liver disease, unspecified
0.679 0.321 0.000
K65-K67 Diseases of peritoneum
0.678 0.322 0.000
S80.9 Superficial injury of lower leg, unspecified
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.322 0.000
R94 Abnormal results of function studies
0.677 0.323 0.000
D52 Folate deficiency anaemia
0.676 0.324 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.675 0.325 0.000
K02.9 Dental caries, unspecified
0.675 0.325 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.675 0.325 0.000
R71 Abnormality of red blood cells
0.674 0.326 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.673 0.327 0.000
D53 Other nutritional anaemias
0.673 0.327 0.000
L40-L45 Papulosquamous disorders
0.673 0.327 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.672 0.327 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.672 0.328 0.000
S82.2 Fracture of shaft of tibia
0.672 0.328 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.672 0.328 0.000
K10 Other diseases of jaws
0.671 0.329 0.000
K03 Other diseases of hard tissues of teeth
0.671 0.329 0.000
K00 Disorders of tooth development and eruption
0.671 0.329 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.671 0.329 0.000
G30-G32 Other degenerative diseases of the nervous system
0.671 0.329 0.000
F40 Phobic anxiety disorders
0.670 0.330 0.000
S88 Traumatic amputation of lower leg
0.669 0.331 0.000
S87 Crushing injury of lower leg
0.669 0.331 0.000
S86 Injury of muscle and tendon at lower leg level
0.669 0.331 0.000
S85 Injury of blood vessels at lower leg level
0.669 0.331 0.000
S84 Injury of nerves at lower leg level
0.669 0.331 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.669 0.331 0.000
M23.3 Other meniscus derangements
0.667 0.333 0.000
I51 Complications and ill-defined descriptions of heart disease
0.666 0.334 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.664 0.336 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.664 0.336 0.000
I67.5 Moyamoya disease
0.664 0.336 0.000
I67.4 Hypertensive encephalopathy
0.664 0.336 0.000
I67.3 Progressive vascular leukoencephalopathy
0.664 0.336 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.664 0.336 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.664 0.336 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.664 0.336 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.664 0.336 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.664 0.336 0.000
T82.3 Mechanical complication of other vascular grafts
0.664 0.336 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.664 0.336 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.664 0.336 0.000
I99 Other and unspecified disorders of circulatory system
0.664 0.336 0.000
H40-H42 Glaucoma
0.663 0.337 0.000
M05-M14 Inflammatory polyarthropathies
0.663 0.337 0.000
M25.54 Pain in joint (Hand)
0.662 0.338 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.662 0.338 0.000
I85 Oesophageal varices
0.661 0.339 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.660 0.340 0.000
K31.6 Fistula of stomach and duodenum
0.659 0.341 0.000
K31.3 Pylorospasm, not elsewhere classified
0.659 0.341 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.659 0.341 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.659 0.341 0.000
K31.0 Acute dilatation of stomach
0.659 0.341 0.000
K09.2 Other cysts of jaw
0.659 0.341 0.000
I38 Endocarditis, valve unspecified
0.659 0.341 0.000
D80-D89 Certain disorders involving the immune mechanism
0.658 0.342 0.000
L03.3 Cellulitis of trunk
0.657 0.343 0.000
I80 Phlebitis and thrombophlebitis
0.657 0.343 0.000
R79 Other abnormal findings of blood chemistry
0.656 0.344 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.656 0.344 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.654 0.346 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.654 0.346 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.654 0.346 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.654 0.346 0.000
G90 Disorders of autonomic nervous system
0.654 0.346 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.654 0.346 0.000
G92 Toxic encephalopathy
0.654 0.346 0.000
I35 Nonrheumatic aortic valve disorders
0.654 0.346 0.000
F48 Other neurotic disorders
0.654 0.346 0.000
F44 Dissociative [conversion] disorders
0.654 0.346 0.000
F42 Obsessive-compulsive disorder
0.654 0.346 0.000
D50.1 Sideropenic dysphagia
0.653 0.347 0.000
M23.4 Loose body in knee
0.652 0.347 0.000
F32 Depressive episode
0.652 0.348 0.000
D61 Other aplastic anaemias
0.651 0.349 0.000
Z57 Occupational exposure to risk-factors
0.651 0.349 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.651 0.349 0.000
I30 Acute pericarditis
0.650 0.349 0.000
I65.2 Occlusion and stenosis of carotid artery
0.650 0.350 0.000
I63.9 Cerebral infarction, unspecified
0.650 0.350 0.000
Chapter XX External causes of morbidity and mortality
0.650 0.350 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.649 0.351 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.649 0.351 0.000
K75.8 Other specified inflammatory liver diseases
0.648 0.352 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.648 0.352 0.000
K75.2 Nonspecific reactive hepatitis
0.648 0.352 0.000
K75.1 Phlebitis of portal vein
0.648 0.352 0.000
G80 Infantile cerebral palsy
0.647 0.352 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.647 0.353 0.000
R20 Disturbances of skin sensation
0.647 0.353 0.000
M25.51 Pain in joint (Shoulder region)
0.647 0.353 0.000
M86 Osteomyelitis
0.647 0.353 0.000
R47.8 Other and unspecified speech disturbances
0.647 0.353 0.000
R30.1 Vesical tenesmus
0.647 0.353 0.000
M90 Osteopathies in diseases classified elsewhere
0.645 0.354 0.000
Z03.8 Observation for other suspected diseases and conditions
0.645 0.355 0.000
R10 Abdominal and pelvic pain
0.645 0.355 0.000
Z71.8 Other specified counselling
0.645 0.355 0.000
F41.1 Generalised anxiety disorder
0.645 0.355 0.000
H91.9 Hearing loss, unspecified
0.645 0.355 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.645 0.355 0.000
T17 Foreign body in respiratory tract
0.644 0.356 0.000
L05.0 Pilonidal cyst with abscess
0.643 0.356 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.643 0.357 0.000
N20-N23 Urolithiasis
0.643 0.357 0.000
M18 Arthrosis of first carpometacarpal joint
0.642 0.358 0.000
S60 Superficial injury of wrist and hand
0.641 0.359 0.000
M46 Other inflammatory spondylopathies
0.641 0.359 0.000
M47 Spondylosis
0.641 0.359 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.640 0.360 0.000
L05.9 Pilonidal cyst without abscess
0.640 0.360 0.000
G82 Paraplegia and tetraplegia
0.639 0.361 0.000
G95 Other diseases of spinal cord
0.638 0.361 0.000
S81 Open wound of lower leg
0.638 0.362 0.000
M31.6 Other giant cell arteritis
0.638 0.362 0.000
N98 Complications associated with artificial fertilisation
0.636 0.363 0.000
N91 Absent, scanty and rare menstruation
0.636 0.363 0.000
N82 Fistulae involving female genital tract
0.636 0.363 0.000
N96 Habitual aborter
0.636 0.363 0.000
R27.0 Ataxia, unspecified
0.636 0.363 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.636 0.364 0.000
N80.8 Other endometriosis
0.635 0.365 0.000
T78.3 Angioneurotic oedema
0.635 0.365 0.000
S40-S49 Injuries to the shoulder and upper arm
0.635 0.365 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.635 0.365 0.000
M24 Other specific joint derangements
0.634 0.365 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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