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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74521173
log Bayes Factor = 5.66609
Chromosome 9   position 28,604,008  (GRCh37) Explore rs74521173 on Ensembl!
Variant rs74521173 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
G90-G99 Other disorders of the nervous system
0.995 0.005 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.989 0.011 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.987 0.013 0.000
I25 Chronic ischaemic heart disease
0.985 0.015 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.977 0.023 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.977 0.023 0.000
M20-M25 Other joint disorders
0.976 0.024 0.000
I30-I52 Other forms of heart disease
0.972 0.028 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.970 0.030 0.000
I71 Aortic aneurysm and dissection
0.968 0.032 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.968 0.032 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.964 0.036 0.000
I22 Subsequent myocardial infarction
0.962 0.038 0.000
M20 Acquired deformities of fingers and toes
0.960 0.040 0.000
M40-M43 Deforming dorsopathies
0.956 0.044 0.000
I50 Heart failure
0.953 0.047 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.952 0.048 0.000
M20.2 Hallux rigidus
0.949 0.051 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.949 0.051 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.937 0.063 0.000
M45-M49 Spondylopathies
0.937 0.063 0.000
G56 Mononeuropathies of upper limb
0.934 0.066 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.933 0.067 0.000
I50.0 Congestive heart failure
0.932 0.068 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.929 0.071 0.000
I51 Complications and ill-defined descriptions of heart disease
0.929 0.071 0.000
G95 Other diseases of spinal cord
0.925 0.075 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.919 0.081 0.000
M41 Scoliosis
0.917 0.083 0.000
M86-M90 Other osteopathies
0.910 0.090 0.000
D50-D53 Nutritional anaemias
0.909 0.091 0.000
M70-M79 Other soft tissue disorders
0.907 0.093 0.000
M24 Other specific joint derangements
0.906 0.094 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.901 0.099 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.896 0.104 0.000
I51.8 Other ill-defined heart diseases
0.889 0.111 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.877 0.123 0.000
M41.9 Scoliosis, unspecified
0.876 0.124 0.000
I74 Arterial embolism and thrombosis
0.870 0.130 0.000
D51 Vitamin B12 deficiency anaemia
0.868 0.132 0.000
I44 Atrioventricular and left bundle-branch block
0.868 0.132 0.000
G20-G26 Extrapyramidal and movement disorders
0.867 0.133 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.865 0.135 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.863 0.137 0.000
G51 Facial nerve disorders
0.859 0.141 0.000
M20.1 Hallux valgus (acquired)
0.857 0.143 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.852 0.148 0.000
I24 Other acute ischaemic heart diseases
0.849 0.151 0.000
S70-S79 Injuries to the hip and thigh
0.845 0.155 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.842 0.158 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.834 0.166 0.000
I25.4 Coronary artery aneurysm
0.834 0.166 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.833 0.167 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.833 0.167 0.000
Q80-Q89 Other congenital malformations
0.831 0.169 0.000
I72 Other aneurysm
0.830 0.170 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.829 0.171 0.000
M80-M85 Disorders of bone density and structure
0.825 0.175 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.825 0.175 0.000
M60-M63 Disorders of muscles
0.824 0.175 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.824 0.176 0.000
M24.0 Loose body in joint
0.822 0.178 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.821 0.178 0.000
M22 Disorders of patella
0.821 0.179 0.000
G95.2 Cord compression, unspecified
0.817 0.183 0.000
S20-S29 Injuries to the thorax
0.815 0.185 0.000
M77 Other enthesopathies
0.814 0.186 0.000
I50.1 Left ventricular failure
0.810 0.190 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.809 0.191 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.809 0.191 0.000
M47 Spondylosis
0.806 0.194 0.000
Q50-Q56 Congenital malformations of genital organs
0.806 0.194 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.803 0.197 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.803 0.197 0.000
M50-M54 Other dorsopathies
0.800 0.200 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.800 0.200 0.000
I44.0 Atrioventricular block, first degree
0.796 0.204 0.000
I35 Nonrheumatic aortic valve disorders
0.795 0.205 0.000
M20.4 Other hammer toe(s) (acquired)
0.793 0.207 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.792 0.208 0.000
G56.0 Carpal tunnel syndrome
0.791 0.209 0.000
I60-I69 Cerebrovascular diseases
0.789 0.211 0.000
G95.8 Other specified diseases of spinal cord
0.787 0.213 0.000
I78 Diseases of capillaries
0.783 0.217 0.000
I24.8 Other forms of acute ischaemic heart disease
0.783 0.217 0.000
D80-D89 Certain disorders involving the immune mechanism
0.781 0.219 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.779 0.221 0.000
I25.2 Old myocardial infarction
0.779 0.221 0.000
G70-G73 Diseases of myoneural junction and muscle
0.777 0.223 0.000
M48 Other spondylopathies
0.774 0.226 0.000
I30 Acute pericarditis
0.774 0.226 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.773 0.227 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.773 0.227 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.772 0.228 0.000
M79.6 Pain in limb
0.771 0.229 0.000
I33 Acute and subacute endocarditis
0.766 0.234 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.763 0.236 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.762 0.238 0.000
G51.0 Bell's palsy
0.762 0.238 0.000
S79 Other and unspecified injuries of hip and thigh
0.762 0.238 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.762 0.238 0.000
I71.0 Dissection of aorta [any part]
0.761 0.239 0.000
Chapter VII Diseases of the eye and adnexa
0.761 0.239 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.760 0.240 0.000
I51.9 Heart disease, unspecified
0.759 0.241 0.000
M00-M03 Infectious arthropathies
0.759 0.241 0.000
M89 Other disorders of bone
0.758 0.242 0.000
M24.2 Disorder of ligament
0.757 0.243 0.000
I74.5 Embolism and thrombosis of iliac artery
0.756 0.244 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.754 0.246 0.000
G90 Disorders of autonomic nervous system
0.754 0.246 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.754 0.246 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.748 0.252 0.000
T91 Sequelae of injuries of neck and trunk
0.747 0.253 0.000
M41.8 Other forms of scoliosis
0.745 0.255 0.000
M86 Osteomyelitis
0.745 0.255 0.000
M77.1 Lateral epicondylitis
0.742 0.257 0.000
I44.1 Atrioventricular block, second degree
0.741 0.259 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.740 0.260 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.737 0.263 0.000
M34 Systemic sclerosis
0.737 0.263 0.000
M51 Other intervertebral disk disorders
0.736 0.264 0.000
M45 Ankylosing spondylitis
0.736 0.264 0.000
G30-G32 Other degenerative diseases of the nervous system
0.735 0.265 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.735 0.265 0.000
G56.8 Other mononeuropathies of upper limb
0.734 0.266 0.000
M46 Other inflammatory spondylopathies
0.733 0.267 0.000
S40-S49 Injuries to the shoulder and upper arm
0.733 0.267 0.000
I67 Other cerebrovascular diseases
0.733 0.267 0.000
I36 Nonrheumatic tricuspid valve disorders
0.732 0.267 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.731 0.269 0.000
I25.3 Aneurysm of heart
0.731 0.269 0.000
M21 Other acquired deformities of limbs
0.731 0.269 0.000
G40-G47 Episodic and paroxysmal disorders
0.731 0.269 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.730 0.270 0.000
M40 Kyphosis and lordosis
0.730 0.270 0.000
S10-S19 Injuries to the neck
0.727 0.273 0.000
G20 Parkinson's disease
0.724 0.276 0.000
M90 Osteopathies in diseases classified elsewhere
0.723 0.277 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.721 0.279 0.000
T66-T78 Other and unspecified effects of external causes
0.719 0.280 0.000
M24.01 Loose body in joint (Shoulder region)
0.719 0.280 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.719 0.281 0.000
T92 Sequelae of injuries of upper limb
0.718 0.282 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.717 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.716 0.284 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.715 0.285 0.000
H43-H45 Disorders of vitreous body and globe
0.714 0.286 0.000
G50 Disorders of trigeminal nerve
0.714 0.286 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.713 0.287 0.000
G92 Toxic encephalopathy
0.713 0.287 0.000
G52 Disorders of other cranial nerves
0.713 0.287 0.000
I70 Atherosclerosis
0.711 0.289 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.711 0.289 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.291 0.000
D52 Folate deficiency anaemia
0.708 0.292 0.000
I49 Other cardiac arrhythmias
0.708 0.292 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.708 0.292 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.708 0.292 0.000
Q85 Phakomatoses, not elsewhere classified
0.707 0.293 0.000
I25.6 Silent myocardial ischaemia
0.706 0.294 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.706 0.294 0.000
M87 Osteonecrosis
0.705 0.295 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.703 0.296 0.000
S79.9 Unspecified injury of hip and thigh
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.702 0.298 0.000
M84 Disorders of continuity of bone
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
D60-D64 Aplastic and other anaemias
0.701 0.299 0.000
I05-I09 Chronic rheumatic heart diseases
0.701 0.299 0.000
I72.0 Aneurysm of carotid artery
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.700 0.300 0.000
M33 Dermatopolymyositis
0.700 0.300 0.000
M32 Systemic lupus erythematosus
0.700 0.300 0.000
M30 Polyarteritis nodosa and related conditions
0.700 0.300 0.000
Q24 Other congenital malformations of heart
0.700 0.300 0.000
G56.1 Other lesions of median nerve
0.700 0.300 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.700 0.300 0.000
M24.6 Ankylosis of joint
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
M22.8 Other disorders of patella
0.699 0.301 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.698 0.302 0.000
I21 Acute myocardial infarction
0.698 0.302 0.000
I52 Other heart disorders in diseases classified elsewhere
0.697 0.303 0.000
I48 Atrial fibrillation and flutter
0.697 0.303 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.697 0.303 0.000
I41 Myocarditis in diseases classified elsewhere
0.697 0.303 0.000
I40 Acute myocarditis
0.697 0.303 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.697 0.303 0.000
I32 Pericarditis in diseases classified elsewhere
0.697 0.303 0.000
M43 Other deforming dorsopathies
0.696 0.304 0.000
S30.0 Contusion of lower back and pelvis
0.696 0.304 0.000
M47.9 Spondylosis, unspecified
0.696 0.304 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
T33-T35 Frostbite
0.695 0.305 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.695 0.305 0.000
T00-T07 Injuries involving multiple body regions
0.695 0.305 0.000
I51.4 Myocarditis, unspecified
0.695 0.305 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.695 0.305 0.000
M60 Myositis
0.695 0.305 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.694 0.306 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.694 0.306 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.694 0.306 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.694 0.306 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.694 0.306 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.694 0.306 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
M24.5 Contracture of joint
0.693 0.307 0.000
D55-D59 Haemolytic anaemias
0.691 0.308 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.691 0.309 0.000
D75 Other diseases of blood and blood-forming organs
0.690 0.310 0.000
M20.3 Other deformity of hallux (acquired)
0.690 0.310 0.000
M31 Other necrotising vasculopathies
0.689 0.310 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.689 0.311 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.689 0.311 0.000
I72.3 Aneurysm of iliac artery
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.687 0.313 0.000
S36 Injury of intra-abdominal organs
0.687 0.313 0.000
M42 Spinal osteochondrosis
0.686 0.314 0.000
Chapter XX External causes of morbidity and mortality
0.685 0.315 0.000
M71 Other bursopathies
0.685 0.315 0.000
T21 Burn and corrosion of trunk
0.685 0.315 0.000
I67.9 Cerebrovascular disease, unspecified
0.684 0.316 0.000
Q00-Q07 Congenital malformations of the nervous system
0.684 0.316 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.683 0.317 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.683 0.317 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.683 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.683 0.317 0.000
G95.1 Vascular myelopathies
0.682 0.317 0.000
I73 Other peripheral vascular diseases
0.682 0.318 0.000
T98 Sequelae of other and unspecified effects of external causes
0.681 0.319 0.000
M99 Biomechanical lesions, not elsewhere classified
0.681 0.319 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.680 0.320 0.000
G95.9 Disease of spinal cord, unspecified
0.677 0.323 0.000
G53.0 Postzoster neuralgia
0.677 0.323 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.676 0.324 0.000
G25 Other extrapyramidal and movement disorders
0.673 0.327 0.000
Chapter I Certain infectious and parasitic diseases
0.673 0.327 0.000
G54 Nerve root and plexus disorders
0.673 0.327 0.000
H43 Disorders of vitreous body
0.673 0.327 0.000
G47 Sleep disorders
0.673 0.327 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.671 0.329 0.000
S50-S59 Injuries to the elbow and forearm
0.670 0.330 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.670 0.330 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.670 0.330 0.000
G56.4 Causalgia
0.669 0.330 0.000
G56.3 Lesion of radial nerve
0.669 0.330 0.000
M24.07 Loose body in joint (Ankle and foot)
0.669 0.331 0.000
H43.1 Vitreous haemorrhage
0.666 0.334 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.666 0.334 0.000
S37 Injury of urinary and pelvic organs
0.666 0.334 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.666 0.334 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.666 0.334 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.666 0.334 0.000
S31 Open wound of abdomen, lower back and pelvis
0.666 0.334 0.000
I51.5 Myocardial degeneration
0.666 0.334 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.666 0.334 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.666 0.334 0.000
G00 Bacterial meningitis, not elsewhere classified
0.664 0.336 0.000
M77.4 Metatarsalgia
0.664 0.336 0.000
S90-S99 Injuries to the ankle and foot
0.664 0.336 0.000
G95.0 Syringomyelia and syringobulbia
0.663 0.337 0.000
G96 Other disorders of central nervous system
0.662 0.338 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.659 0.341 0.000
G24 Dystonia
0.658 0.342 0.000
M41.5 Other secondary scoliosis
0.658 0.342 0.000
M41.4 Neuromuscular scoliosis
0.658 0.342 0.000
M41.3 Thoracogenic scoliosis
0.658 0.342 0.000
M41.2 Other idiopathic scoliosis
0.658 0.342 0.000
M41.1 Juvenile idiopathic scoliosis
0.658 0.342 0.000
M41.0 Infantile idiopathic scoliosis
0.658 0.342 0.000
G91 Hydrocephalus
0.656 0.344 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.656 0.344 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.655 0.345 0.000
G06.1 Intraspinal abscess and granuloma
0.655 0.345 0.000
I44.2 Atrioventricular block, complete
0.654 0.346 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.654 0.346 0.000
M20.0 Deformity of finger(s)
0.653 0.346 0.000
S29 Other and unspecified injuries of thorax
0.653 0.347 0.000
D53 Other nutritional anaemias
0.652 0.348 0.000
Q54 Hypospadias
0.651 0.349 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.650 0.350 0.000
S70 Superficial injury of hip and thigh
0.650 0.350 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.650 0.350 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.650 0.350 0.000
M24.9 Joint derangement, unspecified
0.649 0.350 0.000
M24.7 Protrusio acetabuli
0.649 0.350 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.649 0.350 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.647 0.353 0.000
I99 Other and unspecified disorders of circulatory system
0.646 0.354 0.000
G47.3 Sleep apnoea
0.646 0.354 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.646 0.354 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.646 0.354 0.000
M96.5 Postradiation scoliosis
0.646 0.354 0.000
M96.4 Postsurgical lordosis
0.646 0.354 0.000
M96.3 Postlaminectomy kyphosis
0.646 0.354 0.000
M96.2 Postradiation kyphosis
0.646 0.354 0.000
I44.6 Other and unspecified fascicular block
0.645 0.355 0.000
M79.5 Residual foreign body in soft tissue
0.643 0.357 0.000
M22.2 Patellofemoral disorders
0.643 0.357 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.642 0.357 0.000
S30.2 Contusion of external genital organs
0.642 0.357 0.000
Q52 Other congenital malformations of female genitalia
0.642 0.358 0.000
I49.3 Ventricular premature depolarisation
0.641 0.359 0.000
Q89 Other congenital malformations, not elsewhere classified
0.640 0.360 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.639 0.361 0.000
I78.8 Other diseases of capillaries
0.639 0.361 0.000
I51.0 Cardiac septal defect, acquired
0.638 0.361 0.000
I21.9 Acute myocardial infarction, unspecified
0.638 0.362 0.000
G80 Infantile cerebral palsy
0.637 0.363 0.000
Q82 Other congenital malformations of skin
0.637 0.363 0.000
I51.6 Cardiovascular disease, unspecified
0.636 0.364 0.000
S30.1 Contusion of abdominal wall
0.635 0.365 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.635 0.365 0.000
M89.8 Other specified disorders of bone
0.635 0.365 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.634 0.366 0.000
M79.7 Fibromyalgia
0.633 0.366 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.633 0.367 0.000
I25.5 Ischaemic cardiomyopathy
0.633 0.367 0.000
I97.1 Other functional disturbances following cardiac surgery
0.633 0.367 0.000
G72 Other myopathies
0.632 0.368 0.000
I35.0 Aortic (valve) stenosis
0.631 0.369 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.631 0.369 0.000
I42 Cardiomyopathy
0.630 0.370 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.630 0.370 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.629 0.371 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.629 0.371 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.629 0.371 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.629 0.371 0.000
T36 Poisoning by systemic antibiotics
0.629 0.371 0.000
G82 Paraplegia and tetraplegia
0.629 0.371 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.628 0.372 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.628 0.372 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.628 0.372 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.628 0.372 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.628 0.372 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.628 0.372 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.628 0.372 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.628 0.372 0.000
M76 Enthesopathies of lower limb, excluding foot
0.626 0.373 0.000
M86.9 Osteomyelitis, unspecified
0.627 0.373 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.624 0.376 0.000
I74.8 Embolism and thrombosis of other arteries
0.624 0.376 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.624 0.376 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.624 0.376 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.624 0.376 0.000
M72 Fibroblastic disorders
0.624 0.376 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.623 0.377 0.000
I30.9 Acute pericarditis, unspecified
0.623 0.377 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.622 0.378 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.622 0.378 0.000
D51.2 Transcobalamin II deficiency
0.622 0.378 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.622 0.378 0.000
I44.5 Left posterior fascicular block
0.622 0.378 0.000
I44.4 Left anterior fascicular block
0.622 0.378 0.000
T23 Burn and corrosion of wrist and hand
0.622 0.378 0.000
Q23 Congenital malformations of aortic and mitral valves
0.622 0.378 0.000
M65-M68 Disorders of synovium and tendon
0.621 0.378 0.000
G23 Other degenerative diseases of basal ganglia
0.621 0.378 0.000
G21 Secondary Parkinsonism
0.621 0.378 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.621 0.378 0.000
G22 Parkinsonism in diseases classified elsewhere
0.621 0.378 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.621 0.379 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.621 0.379 0.000
I22.8 Subsequent myocardial infarction of other sites
0.620 0.379 0.000
H16 Keratitis
0.621 0.379 0.000
T95 Sequelae of burns, corrosions and frostbite
0.620 0.380 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.620 0.380 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.620 0.380 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.620 0.380 0.000
I50.9 Heart failure, unspecified
0.619 0.381 0.000
I33.0 Acute and subacute infective endocarditis
0.619 0.381 0.000
M51.8 Other specified intervertebral disk disorders
0.618 0.382 0.000
H10-H13 Disorders of conjunctiva
0.618 0.382 0.000
D80 Immunodeficiency with predominantly antibody defects
0.618 0.382 0.000
M81 Osteoporosis without pathological fracture
0.618 0.382 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.618 0.382 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.617 0.383 0.000
G51.9 Disorder of facial nerve, unspecified
0.616 0.384 0.000
G51.8 Other disorders of facial nerve
0.616 0.384 0.000
G51.4 Facial myokymia
0.616 0.384 0.000
G51.3 Clonic hemifacial spasm
0.616 0.384 0.000
G51.2 Melkersson's syndrome
0.616 0.384 0.000
G51.1 Geniculate ganglionitis
0.616 0.384 0.000
M82 Osteoporosis in diseases classified elsewhere
0.616 0.384 0.000
T90 Sequelae of injuries of head
0.615 0.385 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.614 0.386 0.000
G56.2 Lesion of ulnar nerve
0.613 0.387 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.613 0.387 0.000
M89.5 Osteolysis
0.613 0.387 0.000
M88 Paget's disease of bone [osteitis deformans]
0.613 0.387 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.613 0.387 0.000
M24.02 Loose body in joint (Upper arm)
0.613 0.387 0.000
T14 Injury of unspecified body region
0.612 0.388 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.611 0.388 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.611 0.389 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.611 0.389 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.611 0.389 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.611 0.389 0.000
I24.1 Dressler's syndrome
0.609 0.391 0.000
D84 Other immunodeficiencies
0.609 0.391 0.000
M47.2 Other spondylosis with radiculopathy
0.608 0.392 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.608 0.392 0.000
S78 Traumatic amputation of hip and thigh
0.606 0.394 0.000
S77 Crushing injury of hip and thigh
0.606 0.394 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.606 0.394 0.000
S75 Injury of blood vessels at hip and thigh level
0.606 0.394 0.000
S74 Injury of nerves at hip and thigh level
0.606 0.394 0.000
H18 Other disorders of cornea
0.605 0.395 0.000
S32 Fracture of lumbar spine and pelvis
0.604 0.396 0.000
G57 Mononeuropathies of lower limb
0.604 0.396 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.604 0.396 0.000
M95.0 Acquired deformity of nose
0.604 0.396 0.000
M47.8 Other spondylosis
0.603 0.397 0.000
M60.0 Infective myositis
0.602 0.398 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.600 0.400 0.000
M62 Other disorders of muscle
0.599 0.401 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.598 0.402 0.000
G94.1 Hydrocephalus in neoplastic disease
0.597 0.402 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.597 0.403 0.000
T25 Burn and corrosion of ankle and foot
0.597 0.403 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.597 0.403 0.000
T20 Burn and corrosion of head and neck
0.597 0.403 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.596 0.404 0.000
Q84 Other congenital malformations of integument
0.596 0.404 0.000
Q83 Congenital malformations of breast
0.596 0.404 0.000
Q81 Epidermolysis bullosa
0.596 0.404 0.000
Q80 Congenital ichthyosis
0.596 0.404 0.000
B35-B49 Mycoses
0.596 0.404 0.000
I72.9 Aneurysm of unspecified site
0.595 0.405 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.595 0.405 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.595 0.405 0.000
I72.2 Aneurysm of renal artery
0.595 0.405 0.000
I72.1 Aneurysm of artery of upper extremity
0.595 0.405 0.000
M79.0 Rheumatism, unspecified
0.595 0.405 0.000
I95 Hypotension
0.595 0.405 0.000
Q28 Other congenital malformations of circulatory system
0.595 0.405 0.000
M79.9 Soft tissue disorder, unspecified
0.595 0.405 0.000
M79.3 Panniculitis, unspecified
0.595 0.405 0.000
I35.9 Aortic valve disorder, unspecified
0.594 0.406 0.000
I72.8 Aneurysm of other specified arteries
0.593 0.407 0.000
D50 Iron deficiency anaemia
0.593 0.407 0.000
M91-M94 Chondropathies
0.592 0.408 0.000
M79.64 Pain in limb (Hand)
0.592 0.408 0.000
M83 Adult osteomalacia
0.592 0.408 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.592 0.408 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.591 0.409 0.000
M61 Calcification and ossification of muscle
0.591 0.409 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.591 0.409 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.590 0.410 0.000
M24.09 Loose body in joint (Site unspecified)
0.589 0.411 0.000
M24.08 Loose body in joint (Other)
0.589 0.411 0.000
M24.06 Loose body in joint-Lower leg
0.589 0.411 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.589 0.411 0.000
M24.04 Loose body in joint (Hand)
0.589 0.411 0.000
M24.03 Loose body in joint (Forearm)
0.589 0.411 0.000
M24.00 Loose body in joint (Multiple sites)
0.589 0.411 0.000
M22.1 Recurrent subluxation of patella
0.589 0.411 0.000
M22.9 Disorder of patella, unspecified
0.589 0.411 0.000
M22.0 Recurrent dislocation of patella
0.589 0.411 0.000
S22.2 Fracture of sternum
0.589 0.411 0.000
G61 Inflammatory polyneuropathy
0.589 0.411 0.000
I61 Intracerebral haemorrhage
0.589 0.411 0.000
M90.7 Fracture of bone in neoplastic disease
0.589 0.411 0.000
G58 Other mononeuropathies
0.588 0.412 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.588 0.412 0.000
T68 Hypothermia
0.587 0.413 0.000
Chapter XXII Codes for special purposes
0.587 0.413 0.000
M00 Pyogenic arthritis
0.586 0.413 0.000
G71 Primary disorders of muscles
0.585 0.415 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.585 0.415 0.000
S26 Injury of heart
0.585 0.415 0.000
S25 Injury of blood vessels of thorax
0.585 0.415 0.000
S24 Injury of nerves and spinal cord at thorax level
0.585 0.415 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.585 0.415 0.000
S21 Open wound of thorax
0.585 0.415 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.585 0.415 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.584 0.416 0.000
M80 Osteoporosis with pathological fracture
0.584 0.416 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.584 0.416 0.000
M77.5 Other enthesopathy of foot
0.584 0.416 0.000
M77.3 Calcaneal spur
0.584 0.416 0.000
M77.2 Periarthritis of wrist
0.584 0.416 0.000
M70.6 Trochanteric bursitis
0.583 0.416 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.582 0.418 0.000
M70.2 Olecranon bursitis
0.581 0.418 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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