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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74678038
log Bayes Factor = 16.2265
Chromosome 5   position 132,614,044  (GRCh37) Explore rs74678038 on Ensembl!
Variant rs74678038 is part of Cluster X0073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.992 0.008 0.000
Z92 Personal history of medical treatment
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
C15-C26 Malignant neoplasms of digestive organs
0.981 0.019 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.978 0.022 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.974 0.026 0.000
J09-J18 Influenza and pneumonia
0.974 0.026 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.970 0.030 0.000
E86 Volume depletion
0.967 0.033 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.965 0.035 0.000
Chapter I Certain infectious and parasitic diseases
0.962 0.038 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.961 0.039 0.000
J18 Pneumonia, organism unspecified
0.958 0.042 0.000
C18 Malignant neoplasm of colon
0.957 0.043 0.000
I60-I69 Cerebrovascular diseases
0.957 0.043 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.955 0.045 0.000
Chapter V Mental and behavioural disorders
0.946 0.054 0.000
J18.1 Lobar pneumonia, unspecified
0.945 0.055 0.000
I30-I52 Other forms of heart disease
0.940 0.060 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.940 0.060 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.938 0.062 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.930 0.070 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.930 0.070 0.000
Z92.3 Personal history of irradiation
0.924 0.076 0.000
Z93 Artificial opening status
0.923 0.077 0.000
C77.2 Intra-abdominal lymph nodes
0.919 0.081 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.918 0.082 0.000
R21 Rash and other nonspecific skin eruption
0.916 0.084 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.910 0.090 0.000
J20-J22 Other acute lower respiratory infections
0.907 0.093 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.903 0.097 0.000
J90-J94 Other diseases of pleura
0.900 0.100 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.898 0.102 0.000
I80 Phlebitis and thrombophlebitis
0.897 0.103 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.894 0.106 0.000
R47-R49 Symptoms and signs involving speech and voice
0.891 0.109 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.891 0.109 0.000
E87.6 Hypokalaemia
0.889 0.111 0.000
Z85 Personal history of malignant neoplasm
0.887 0.113 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.887 0.113 0.000
I50 Heart failure
0.885 0.115 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.875 0.125 0.000
R40 Somnolence, stupor and coma
0.874 0.126 0.000
R94 Abnormal results of function studies
0.873 0.127 0.000
C79 Secondary malignant neoplasm of other sites
0.870 0.130 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.867 0.133 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.866 0.134 0.000
C51-C58 Malignant neoplasms of female genital organs
0.866 0.134 0.000
C18.2 Ascending colon
0.865 0.135 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.863 0.137 0.000
L57.0 Actinic keratosis
0.861 0.139 0.000
Chapter VII Diseases of the eye and adnexa
0.859 0.141 0.000
I69 Sequelae of cerebrovascular disease
0.858 0.142 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.850 0.150 0.000
L89 Decubitus ulcer
0.849 0.151 0.000
C18.0 Caecum
0.847 0.153 0.000
L40-L45 Papulosquamous disorders
0.847 0.153 0.000
E83 Disorders of mineral metabolism
0.845 0.155 0.000
I05-I09 Chronic rheumatic heart diseases
0.845 0.155 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.843 0.157 0.000
J22 Unspecified acute lower respiratory infection
0.843 0.157 0.000
Chapter VIII Diseases of the ear and mastoid process
0.843 0.157 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.843 0.157 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.842 0.158 0.000
Chapter XXII Codes for special purposes
0.842 0.158 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.840 0.160 0.000
C80 Malignant neoplasm without specification of site
0.839 0.161 0.000
C77.1 Intrathoracic lymph nodes
0.839 0.161 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.839 0.161 0.000
C18.9 Colon, unspecified
0.838 0.162 0.000
Z86 Personal history of certain other diseases
0.838 0.162 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.835 0.165 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.835 0.165 0.000
A30-A49 Other bacterial diseases
0.833 0.167 0.000
Z93.2 Ileostomy status
0.832 0.168 0.000
E85 Amyloidosis
0.831 0.169 0.000
C50-C50 Malignant neoplasm of breast
0.831 0.169 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.829 0.171 0.000
I63 Cerebral infarction
0.829 0.171 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.828 0.172 0.000
Z86.7 Personal history of diseases of the circulatory system
0.826 0.174 0.000
C34 Malignant neoplasm of bronchus and lung
0.825 0.175 0.000
F30-F39 Mood [affective] disorders
0.824 0.176 0.000
J90 Pleural effusion, not elsewhere classified
0.823 0.177 0.000
B95-B98 Bacterial, viral and other infectious agents
0.822 0.178 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.819 0.181 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.819 0.181 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.816 0.184 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.815 0.185 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.814 0.186 0.000
D00-D09 In situ neoplasms
0.812 0.188 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.811 0.189 0.000
L20-L30 Dermatitis and eczema
0.810 0.190 0.000
A00-A09 Intestinal infectious diseases
0.810 0.190 0.000
R47 Speech disturbances, not elsewhere classified
0.809 0.191 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.809 0.191 0.000
R06 Abnormalities of breathing
0.806 0.194 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.805 0.195 0.000
J95-J99 Other diseases of the respiratory system
0.805 0.195 0.000
R94.5 Abnormal results of liver function studies
0.804 0.196 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.803 0.197 0.000
C77.0 Lymph nodes of head, face and neck
0.801 0.199 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.797 0.203 0.000
J30-J39 Other diseases of upper respiratory tract
0.797 0.203 0.000
R40.0 Somnolence
0.794 0.206 0.000
I50.9 Heart failure, unspecified
0.794 0.206 0.000
Z93.3 Colostomy status
0.794 0.206 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.794 0.206 0.000
I45 Other conduction disorders
0.793 0.207 0.000
L82 Seborrhoeic keratosis
0.791 0.209 0.000
I49 Other cardiac arrhythmias
0.789 0.211 0.000
C16 Malignant neoplasm of stomach
0.788 0.212 0.000
I67 Other cerebrovascular diseases
0.786 0.214 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.784 0.216 0.000
R41.0 Disorientation, unspecified
0.783 0.217 0.000
C78.2 Secondary malignant neoplasm of pleura
0.782 0.218 0.000
Z92.8 Personal history of other medical treatment
0.781 0.219 0.000
C15 Malignant neoplasm of oesophagus
0.778 0.222 0.000
R00 Abnormalities of heart beat
0.777 0.223 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.776 0.224 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.773 0.227 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.773 0.227 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.769 0.231 0.000
C34.3 Lower lobe, bronchus or lung
0.766 0.234 0.000
Z51 Other medical care
0.764 0.236 0.000
E87.5 Hyperkalaemia
0.763 0.237 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.762 0.238 0.000
R47.0 Dysphasia and aphasia
0.761 0.239 0.000
M70-M79 Other soft tissue disorders
0.760 0.240 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.760 0.240 0.000
R23 Other skin changes
0.757 0.243 0.000
C64-C68 Malignant neoplasms of urinary tract
0.756 0.244 0.000
L40 Psoriasis
0.756 0.244 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.754 0.246 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.754 0.246 0.000
I50.1 Left ventricular failure
0.752 0.248 0.000
C18.3 Hepatic flexure
0.752 0.248 0.000
C25 Malignant neoplasm of pancreas
0.748 0.252 0.000
C90.0 Multiple myeloma
0.747 0.253 0.000
C18.4 Transverse colon
0.747 0.253 0.000
F60-F69 Disorders of adult personality and behaviour
0.747 0.253 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.746 0.254 0.000
E20-E35 Disorders of other endocrine glands
0.745 0.255 0.000
Z60 Problems related to social environment
0.745 0.255 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.744 0.256 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.744 0.256 0.000
M45-M49 Spondylopathies
0.742 0.258 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.741 0.259 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.741 0.259 0.000
C77.4 Inguinal and lower limb lymph nodes
0.740 0.260 0.000
I20-I25 Ischaemic heart diseases
0.740 0.260 0.000
L50-L54 Urticaria and erythema
0.738 0.262 0.000
B35-B49 Mycoses
0.737 0.263 0.000
C77.5 Intrapelvic lymph nodes
0.735 0.265 0.000
S80-S89 Injuries to the knee and lower leg
0.735 0.265 0.000
Z51.1 Chemotherapy session for neoplasm
0.735 0.265 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.735 0.265 0.000
R40.2 Coma, unspecified
0.730 0.270 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.728 0.271 0.000
Z97 Presence of other devices
0.728 0.272 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.728 0.272 0.000
F99-F99 Unspecified mental disorder
0.726 0.274 0.000
I27 Other pulmonary heart diseases
0.726 0.274 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.726 0.274 0.000
L89.1 Stage II decubitus ulcer
0.725 0.275 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.725 0.275 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.725 0.275 0.000
C53 Malignant neoplasm of cervix uteri
0.724 0.276 0.000
E83.1 Disorders of iron metabolism
0.722 0.278 0.000
Chapter XX External causes of morbidity and mortality
0.720 0.280 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.719 0.281 0.000
C78.7 Secondary malignant neoplasm of liver
0.719 0.281 0.000
J93 Pneumothorax
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R04 Haemorrhage from respiratory passages
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
E40-E46 Malnutrition
0.715 0.284 0.000
I46 Cardiac arrest
0.715 0.285 0.000
I10-I15 Hypertensive diseases
0.715 0.285 0.000
E88 Other metabolic disorders
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
C54 Malignant neoplasm of corpus uteri
0.715 0.285 0.000
J18.9 Pneumonia, unspecified
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.714 0.286 0.000
I35 Nonrheumatic aortic valve disorders
0.713 0.287 0.000
F41 Other anxiety disorders
0.713 0.287 0.000
E78.5 Hyperlipidaemia, unspecified
0.713 0.287 0.000
F31 Bipolar affective disorder
0.712 0.288 0.000
Z57 Occupational exposure to risk-factors
0.712 0.288 0.000
Z93.5 Cystostomy status
0.712 0.288 0.000
E85.4 Organ-limited amyloidosis
0.712 0.288 0.000
Z89 Acquired absence of limb
0.711 0.289 0.000
Z84 Family history of other conditions
0.711 0.289 0.000
Z81 Family history of mental and behavioural disorders
0.711 0.289 0.000
C77.3 Axillary and upper limb lymph nodes
0.711 0.289 0.000
F80-F89 Disorders of psychological development
0.711 0.289 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.710 0.290 0.000
C50 Malignant neoplasm of breast
0.710 0.290 0.000
H53-H54 Visual disturbances and blindness
0.709 0.291 0.000
Z92.9 Personal history of medical treatment, unspecified
0.709 0.291 0.000
Z92.5 Personal history of rehabilitation measures
0.709 0.291 0.000
Z92.0 Personal history of contraception
0.709 0.291 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.707 0.292 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
J60-J70 Lung diseases due to external agents
0.706 0.294 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.705 0.295 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.704 0.296 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.704 0.296 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.704 0.296 0.000
C21 Malignant neoplasm of anus and anal canal
0.704 0.296 0.000
C17 Malignant neoplasm of small intestine
0.704 0.296 0.000
C23 Malignant neoplasm of gallbladder
0.704 0.296 0.000
R06.1 Stridor
0.703 0.297 0.000
I62 Other nontraumatic intracranial haemorrhage
0.703 0.297 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.702 0.298 0.000
L84 Corns and callosities
0.702 0.298 0.000
B15-B19 Viral hepatitis
0.702 0.298 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.702 0.298 0.000
C77.8 Lymph nodes of multiple regions
0.701 0.299 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.701 0.299 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.700 0.300 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.699 0.301 0.000
R20 Disturbances of skin sensation
0.699 0.301 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.699 0.301 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.698 0.302 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
C95 Leukaemia of unspecified cell type
0.698 0.302 0.000
C94 Other leukaemias of specified cell type
0.698 0.302 0.000
C93 Monocytic leukaemia
0.698 0.302 0.000
C92 Myeloid leukaemia
0.698 0.302 0.000
C91 Lymphoid leukaemia
0.698 0.302 0.000
C88 Malignant immunoproliferative diseases
0.698 0.302 0.000
C86 Other specified types of T/NK-cell lymphoma
0.698 0.302 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.698 0.302 0.000
C81 Hodgkin's disease
0.698 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.698 0.302 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.698 0.302 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.698 0.302 0.000
J12 Viral pneumonia, not elsewhere classified
0.698 0.302 0.000
J11 Influenza, virus not identified
0.698 0.302 0.000
J10 Influenza due to identified influenza virus
0.698 0.302 0.000
J14 Pneumonia due to Haemophilus influenzae
0.698 0.302 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.698 0.302 0.000
J09 Influenza due to certain identified influenza virus
0.698 0.302 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.697 0.303 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.697 0.303 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.696 0.304 0.000
Z95.1 Presence of aortocoronary bypass graft
0.695 0.305 0.000
L29 Pruritus
0.695 0.305 0.000
I83 Varicose veins of lower extremities
0.695 0.305 0.000
M65-M68 Disorders of synovium and tendon
0.695 0.305 0.000
Z51.5 Palliative care
0.695 0.305 0.000
I69.3 Sequelae of cerebral infarction
0.693 0.307 0.000
I67.8 Other specified cerebrovascular diseases
0.691 0.309 0.000
H65-H75 Diseases of middle ear and mastoid
0.690 0.310 0.000
C85.1 B-cell lymphoma, unspecified
0.690 0.310 0.000
B99-B99 Other infectious diseases
0.690 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.690 0.310 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.690 0.310 0.000
B65-B83 Helminthiases
0.690 0.310 0.000
B50-B64 Protozoal diseases
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.690 0.310 0.000
A80-A89 Viral infections of the central nervous system
0.690 0.310 0.000
A75-A79 Rickettsioses
0.690 0.310 0.000
A70-A74 Other diseases caused by chlamydiae
0.690 0.310 0.000
A65-A69 Other spirochaetal diseases
0.690 0.310 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.690 0.310 0.000
A20-A28 Certain zoonotic bacterial diseases
0.690 0.310 0.000
A15-A19 Tuberculosis
0.690 0.310 0.000
I42 Cardiomyopathy
0.689 0.310 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.689 0.310 0.000
E87.4 Mixed disorder of acid-base balance
0.689 0.311 0.000
E87.3 Alkalosis
0.689 0.311 0.000
E87.0 Hyperosmolality and hypernatraemia
0.689 0.311 0.000
H60-H62 Diseases of external ear
0.689 0.311 0.000
Z63 Other problems related to primary support group, including family circumstances
0.689 0.311 0.000
I45.1 Other and unspecified right bundle-branch block
0.688 0.312 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.688 0.312 0.000
I38 Endocarditis, valve unspecified
0.688 0.312 0.000
E50-E64 Other nutritional deficiencies
0.688 0.312 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.687 0.313 0.000
A41 Other septicaemia
0.687 0.313 0.000
S40-S49 Injuries to the shoulder and upper arm
0.687 0.313 0.000
J18.8 Other pneumonia, organism unspecified
0.686 0.313 0.000
J18.2 Hypostatic pneumonia, unspecified
0.686 0.313 0.000
J18.0 Bronchopneumonia, unspecified
0.686 0.313 0.000
C78.0 Secondary malignant neoplasm of lung
0.687 0.313 0.000
C18.8 Overlapping lesion of colon
0.686 0.314 0.000
C18.6 Descending colon
0.686 0.314 0.000
C18.5 Splenic flexure
0.686 0.314 0.000
C18.1 Appendix
0.686 0.314 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.686 0.314 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.686 0.314 0.000
I63.9 Cerebral infarction, unspecified
0.686 0.314 0.000
C77.9 Lymph node, unspecified
0.685 0.315 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.685 0.315 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.685 0.315 0.000
R00.0 Tachycardia, unspecified
0.684 0.316 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.684 0.316 0.000
A49 Bacterial infection of unspecified site
0.683 0.317 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.682 0.318 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.682 0.318 0.000
J00-J06 Acute upper respiratory infections
0.681 0.319 0.000
C80.9 Malignant neoplasm, unspecified
0.680 0.320 0.000
I50.0 Congestive heart failure
0.680 0.320 0.000
R06.0 Dyspnoea
0.680 0.320 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.680 0.320 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.679 0.321 0.000
R73 Elevated blood glucose level
0.678 0.322 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.678 0.322 0.000
F70-F79 Mental retardation
0.678 0.322 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.678 0.322 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.676 0.324 0.000
I08 Multiple valve diseases
0.675 0.325 0.000
C71 Malignant neoplasm of brain
0.675 0.325 0.000
M75 Shoulder lesions
0.674 0.326 0.000
T39.0 Salicylates
0.674 0.326 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.674 0.326 0.000
I52 Other heart disorders in diseases classified elsewhere
0.674 0.326 0.000
I48 Atrial fibrillation and flutter
0.674 0.326 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.674 0.326 0.000
I41 Myocarditis in diseases classified elsewhere
0.674 0.326 0.000
I40 Acute myocarditis
0.674 0.326 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.674 0.326 0.000
I37 Pulmonary valve disorders
0.674 0.326 0.000
I36 Nonrheumatic tricuspid valve disorders
0.674 0.326 0.000
I32 Pericarditis in diseases classified elsewhere
0.674 0.326 0.000
I30 Acute pericarditis
0.674 0.326 0.000
R46 Symptoms and signs involving appearance and behaviour
0.674 0.326 0.000
R45 Symptoms and signs involving emotional state
0.674 0.326 0.000
R43 Disturbances of smell and taste
0.674 0.326 0.000
E89.3 Postprocedural hypopituitarism
0.674 0.326 0.000
I61 Intracerebral haemorrhage
0.672 0.328 0.000
I05 Rheumatic mitral valve diseases
0.672 0.328 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.670 0.330 0.000
H10-H13 Disorders of conjunctiva
0.670 0.330 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.670 0.330 0.000
Z50 Care involving use of rehabilitation procedures
0.670 0.330 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.669 0.331 0.000
Z83 Family history of other specific disorders
0.669 0.331 0.000
I49.9 Cardiac arrhythmia, unspecified
0.668 0.332 0.000
B25-B34 Other viral diseases
0.668 0.332 0.000
J98 Other respiratory disorders
0.668 0.332 0.000
L81 Other disorders of pigmentation
0.668 0.332 0.000
J30 Vasomotor and allergic rhinitis
0.667 0.332 0.000
E16 Other disorders of pancreatic internal secretion
0.667 0.333 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.667 0.333 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.667 0.333 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.667 0.333 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.667 0.333 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.667 0.333 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.667 0.333 0.000
L58 Radiodermatitis
0.667 0.333 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.667 0.333 0.000
L55 Sunburn
0.667 0.333 0.000
Z95.0 Presence of cardiac pacemaker
0.666 0.334 0.000
E00-E07 Disorders of thyroid gland
0.666 0.334 0.000
C34.9 Bronchus or lung, unspecified
0.666 0.334 0.000
I86 Varicose veins of other sites
0.662 0.338 0.000
Z22 Carrier of infectious disease
0.662 0.338 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.662 0.338 0.000
Z93.9 Artificial opening status, unspecified
0.662 0.338 0.000
Z93.8 Other artificial opening status
0.662 0.338 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.662 0.338 0.000
Z93.0 Tracheostomy status
0.662 0.338 0.000
M47 Spondylosis
0.662 0.338 0.000
D10-D36 Benign neoplasms
0.661 0.339 0.000
H55-H59 Other disorders of eye and adnexa
0.661 0.339 0.000
R94.3 Abnormal results of cardiovascular function studies
0.660 0.339 0.000
L40.9 Psoriasis, unspecified
0.660 0.340 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.660 0.340 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.659 0.341 0.000
I88 Nonspecific lymphadenitis
0.658 0.342 0.000
I87 Other disorders of veins
0.658 0.342 0.000
I82 Other venous embolism and thrombosis
0.658 0.342 0.000
I81 Portal vein thrombosis
0.658 0.342 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.657 0.342 0.000
R49 Voice disturbances
0.657 0.343 0.000
I22 Subsequent myocardial infarction
0.656 0.344 0.000
Z98 Other postsurgical states
0.656 0.344 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.656 0.344 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.656 0.344 0.000
J38.3 Other diseases of vocal cords
0.655 0.345 0.000
D03 Melanoma in situ
0.654 0.345 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.654 0.346 0.000
R06.8 Other and unspecified abnormalities of breathing
0.654 0.346 0.000
C20 Malignant neoplasm of rectum
0.653 0.347 0.000
T79-T79 Certain early complications of trauma
0.653 0.347 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.653 0.347 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.653 0.347 0.000
L94 Other localised connective tissue disorders
0.653 0.347 0.000
L93 Lupus erythematosus
0.653 0.347 0.000
L87 Transepidermal elimination disorders
0.653 0.347 0.000
L88 Pyoderma gangrenosum
0.653 0.347 0.000
L86 Keratoderma in diseases classified elsewhere
0.653 0.347 0.000
L83 Acanthosis nigricans
0.653 0.347 0.000
L80 Vitiligo
0.653 0.347 0.000
E65-E68 Obesity and other hyperalimentation
0.651 0.349 0.000
R04.0 Epistaxis
0.651 0.349 0.000
J21 Acute bronchiolitis
0.650 0.349 0.000
J20 Acute bronchitis
0.650 0.349 0.000
C16.0 Cardia
0.650 0.350 0.000
Z94 Transplanted organ and tissue status
0.649 0.351 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.649 0.351 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.649 0.351 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.649 0.351 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.649 0.351 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.648 0.352 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.648 0.352 0.000
C85.0 Lymphosarcoma
0.648 0.352 0.000
U80 Agent resistant to penicillin and related antibiotics
0.647 0.353 0.000
Z95.3 Presence of xenogenic heart valve
0.646 0.354 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.646 0.354 0.000
J94 Other pleural conditions
0.645 0.355 0.000
J91 Pleural effusion in conditions classified elsewhere
0.645 0.355 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.645 0.355 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.645 0.355 0.000
F33 Recurrent depressive disorder
0.644 0.356 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.644 0.356 0.000
I60 Subarachnoid haemorrhage
0.644 0.356 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.644 0.356 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.644 0.356 0.000
C32 Malignant neoplasm of larynx
0.644 0.356 0.000
C31 Malignant neoplasm of accessory sinuses
0.644 0.356 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.644 0.356 0.000
C37 Malignant neoplasm of thymus
0.644 0.356 0.000
C33 Malignant neoplasm of trachea
0.644 0.356 0.000
Z60.2 Living alone
0.644 0.356 0.000
Z90.1 Acquired absence of breast(s)
0.644 0.356 0.000
E87.7 Fluid overload
0.643 0.356 0.000
I26 Pulmonary embolism
0.643 0.357 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.643 0.357 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.643 0.357 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
C22.0 Liver cell carcinoma
0.642 0.358 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.642 0.358 0.000
C15.9 Oesophagus, unspecified
0.642 0.358 0.000
T33-T35 Frostbite
0.641 0.359 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.641 0.359 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.641 0.359 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.641 0.359 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.641 0.359 0.000
T00-T07 Injuries involving multiple body regions
0.641 0.359 0.000
S90-S99 Injuries to the ankle and foot
0.641 0.359 0.000
S10-S19 Injuries to the neck
0.641 0.359 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.640 0.360 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.640 0.360 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.639 0.361 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.639 0.361 0.000
L57.5 Actinic granuloma
0.639 0.361 0.000
L57.4 Cutis laxa senilis
0.639 0.361 0.000
L57.3 Poikiloderma of Civatte
0.639 0.361 0.000
L57.2 Cutis rhomboidalis nuchae
0.639 0.361 0.000
L57.1 Actinic reticuloid
0.639 0.361 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.637 0.363 0.000
I34 Nonrheumatic mitral valve disorders
0.636 0.363 0.000
S81 Open wound of lower leg
0.636 0.364 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.636 0.364 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.636 0.364 0.000
Z85.6 Personal history of leukaemia
0.636 0.364 0.000
Z65 Problems related to other psychosocial circumstances
0.636 0.364 0.000
Z64 Problems related to certain psychosocial circumstances
0.636 0.364 0.000
Z62 Other problems related to upbringing
0.636 0.364 0.000
Z61 Problems related to negative life events in childhood
0.636 0.364 0.000
Z59 Problems related to housing and economic circumstances
0.636 0.364 0.000
Z58 Problems related to physical environment
0.636 0.364 0.000
Z56 Problems related to employment and unemployment
0.636 0.364 0.000
Z55 Problems related to education and literacy
0.636 0.364 0.000
D04 Carcinoma in situ of skin
0.635 0.365 0.000
L28 Lichen simplex chronicus and prurigo
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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