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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74767006
log Bayes Factor = 9.9283
Chromosome 7   position 25,076,186  (GRCh37) Explore rs74767006 on Ensembl!
Variant rs74767006 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
A30-A49 Other bacterial diseases
0.982 0.018 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.981 0.019 0.000
R30-R39 Symptoms and signs involving the urinary system
0.975 0.025 0.000
M20.4 Other hammer toe(s) (acquired)
0.974 0.026 0.000
A41 Other septicaemia
0.973 0.027 0.000
M70-M79 Other soft tissue disorders
0.972 0.028 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.972 0.028 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.967 0.033 0.000
R33 Retention of urine
0.966 0.034 0.000
M20.1 Hallux valgus (acquired)
0.963 0.037 0.000
Chapter IX Diseases of the circulatory system
0.962 0.038 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.959 0.041 0.000
K50-K52 Noninfective enteritis and colitis
0.958 0.042 0.000
T79-T79 Certain early complications of trauma
0.957 0.043 0.000
Chapter XI Diseases of the digestive system
0.957 0.043 0.000
M40-M43 Deforming dorsopathies
0.955 0.045 0.000
K51 Ulcerative colitis
0.954 0.046 0.000
A41.9 Septicaemia, unspecified
0.953 0.047 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.946 0.054 0.000
K50 Crohn's disease [regional enteritis]
0.944 0.056 0.000
K51.9 Ulcerative colitis, unspecified
0.938 0.062 0.000
S50-S59 Injuries to the elbow and forearm
0.937 0.063 0.000
R32 Unspecified urinary incontinence
0.932 0.068 0.000
T91 Sequelae of injuries of neck and trunk
0.927 0.073 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.926 0.074 0.000
M24 Other specific joint derangements
0.925 0.075 0.000
M79.0 Rheumatism, unspecified
0.925 0.075 0.000
K50.9 Crohn's disease, unspecified
0.924 0.076 0.000
M20.2 Hallux rigidus
0.924 0.076 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.922 0.078 0.000
Chapter VIII Diseases of the ear and mastoid process
0.919 0.081 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.919 0.081 0.000
S60-S69 Injuries to the wrist and hand
0.916 0.084 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
M79.6 Pain in limb
0.908 0.092 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.902 0.098 0.000
S80-S89 Injuries to the knee and lower leg
0.896 0.104 0.000
M86-M90 Other osteopathies
0.895 0.105 0.000
I73 Other peripheral vascular diseases
0.895 0.105 0.000
K65-K67 Diseases of peritoneum
0.890 0.110 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.886 0.114 0.000
M41 Scoliosis
0.885 0.115 0.000
M22 Disorders of patella
0.884 0.116 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.884 0.116 0.000
H60-H62 Diseases of external ear
0.882 0.118 0.000
M65-M68 Disorders of synovium and tendon
0.876 0.124 0.000
F03 Unspecified dementia
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.873 0.127 0.000
I95 Hypotension
0.873 0.127 0.000
M80-M85 Disorders of bone density and structure
0.872 0.128 0.000
R50-R69 General symptoms and signs
0.870 0.130 0.000
R25 Abnormal involuntary movements
0.869 0.131 0.000
I30-I52 Other forms of heart disease
0.866 0.134 0.000
K65 Peritonitis
0.866 0.134 0.000
W20-W49 Exposure to inanimate mechanical forces
0.864 0.135 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.864 0.136 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.864 0.136 0.000
K51.8 Other ulcerative colitis
0.862 0.138 0.000
S82 Fracture of lower leg, including ankle
0.861 0.139 0.000
S10-S19 Injuries to the neck
0.860 0.140 0.000
T92 Sequelae of injuries of upper limb
0.859 0.141 0.000
M89 Other disorders of bone
0.858 0.142 0.000
S90-S99 Injuries to the ankle and foot
0.857 0.143 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.854 0.146 0.000
R80 Isolated proteinuria
0.847 0.153 0.000
B35-B49 Mycoses
0.844 0.156 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.844 0.156 0.000
R54 Senility
0.843 0.157 0.000
I73.0 Raynaud's syndrome
0.840 0.160 0.000
A15-A19 Tuberculosis
0.839 0.161 0.000
M41.9 Scoliosis, unspecified
0.835 0.165 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.835 0.165 0.000
V40-V49 Car occupant injured in transport accident
0.833 0.167 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.832 0.168 0.000
T91.3 Sequelae of injury of spinal cord
0.831 0.169 0.000
M43 Other deforming dorsopathies
0.828 0.172 0.000
H61 Other disorders of external ear
0.826 0.174 0.000
M79.2 Neuralgia and neuritis, unspecified
0.825 0.175 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.825 0.175 0.000
K90-K93 Other diseases of the digestive system
0.821 0.179 0.000
M89.9 Disorder of bone, unspecified
0.819 0.181 0.000
F99-F99 Unspecified mental disorder
0.819 0.181 0.000
M77 Other enthesopathies
0.819 0.181 0.000
M79.64 Pain in limb (Hand)
0.815 0.185 0.000
M24.1 Other articular cartilage disorders
0.814 0.186 0.000
K65.0 Acute peritonitis
0.813 0.187 0.000
I74 Arterial embolism and thrombosis
0.808 0.192 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.805 0.195 0.000
I73.9 Peripheral vascular disease, unspecified
0.804 0.196 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.801 0.199 0.000
W22 Striking against or struck by other objects
0.801 0.199 0.000
R25.1 Tremor, unspecified
0.801 0.199 0.000
T98 Sequelae of other and unspecified effects of external causes
0.801 0.199 0.000
M65 Synovitis and tenosynovitis
0.800 0.200 0.000
M79.69 Pain in limb (Site unspecified)
0.798 0.202 0.000
I95.2 Hypotension due to drugs
0.798 0.202 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.798 0.202 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.795 0.205 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.794 0.206 0.000
M21 Other acquired deformities of limbs
0.793 0.207 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.793 0.207 0.000
W00-W19 Falls
0.792 0.208 0.000
R27 Other lack of coordination
0.792 0.208 0.000
S65 Injury of blood vessels at wrist and hand level
0.792 0.208 0.000
Y00-Y09 Assault
0.792 0.208 0.000
T91.1 Sequelae of fracture of spine
0.792 0.208 0.000
S51 Open wound of forearm
0.792 0.208 0.000
R57 Shock, not elsewhere classified
0.789 0.211 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.786 0.214 0.000
M79.1 Myalgia
0.786 0.214 0.000
I50 Heart failure
0.786 0.214 0.000
S64 Injury of nerves at wrist and hand level
0.785 0.215 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.783 0.217 0.000
T00-T07 Injuries involving multiple body regions
0.781 0.219 0.000
M79.62 Pain in limb (Upper arm)
0.779 0.221 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.777 0.223 0.000
B15-B19 Viral hepatitis
0.775 0.225 0.000
M79.9 Soft tissue disorder, unspecified
0.775 0.225 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.773 0.227 0.000
M22.8 Other disorders of patella
0.772 0.228 0.000
S00-S09 Injuries to the head
0.771 0.229 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.769 0.231 0.000
H61.2 Impacted cerumen
0.768 0.232 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.768 0.232 0.000
M65.3 Trigger finger
0.768 0.232 0.000
F01 Vascular dementia
0.766 0.234 0.000
Y52 Agents primarily affecting the cardiovascular system
0.765 0.235 0.000
A49 Bacterial infection of unspecified site
0.764 0.236 0.000
K50.8 Other Crohn's disease
0.763 0.237 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.763 0.237 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.762 0.238 0.000
H60 Otitis externa
0.762 0.238 0.000
R61 Hyperhidrosis
0.761 0.239 0.000
I72 Other aneurysm
0.760 0.240 0.000
M30 Polyarteritis nodosa and related conditions
0.759 0.241 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
R60 Oedema, not elsewhere classified
0.758 0.242 0.000
V01-V09 Pedestrian injured in transport accident
0.756 0.244 0.000
R26 Abnormalities of gait and mobility
0.756 0.244 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.754 0.246 0.000
K50.1 Crohn's disease of large intestine
0.752 0.248 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.751 0.249 0.000
M84 Disorders of continuity of bone
0.750 0.250 0.000
R47-R49 Symptoms and signs involving speech and voice
0.750 0.250 0.000
F10.0 Acute intoxication
0.747 0.253 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.747 0.253 0.000
M85 Other disorders of bone density and structure
0.746 0.254 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.746 0.254 0.000
A46 Erysipelas
0.745 0.255 0.000
K91.4 Colostomy and enterostomy malfunction
0.745 0.255 0.000
M65.34 Trigger finger-Hand
0.745 0.255 0.000
Y44 Agents primarily affecting blood constituents
0.745 0.255 0.000
S50 Superficial injury of forearm
0.744 0.256 0.000
I44 Atrioventricular and left bundle-branch block
0.744 0.256 0.000
I50.1 Left ventricular failure
0.743 0.257 0.000
X20-X29 Contact with venomous animals and plants
0.742 0.258 0.000
T66-T78 Other and unspecified effects of external causes
0.742 0.258 0.000
I35 Nonrheumatic aortic valve disorders
0.742 0.258 0.000
Y43 Primarily systemic agents
0.740 0.260 0.000
W22.9 Unspecified place
0.740 0.260 0.000
S52 Fracture of forearm
0.740 0.260 0.000
S56 Injury of muscle and tendon at forearm level
0.739 0.261 0.000
K65.9 Peritonitis, unspecified
0.739 0.261 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.737 0.263 0.000
S82.3 Fracture of lower end of tibia
0.736 0.263 0.000
S59 Other and unspecified injuries of forearm
0.735 0.265 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.733 0.266 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.733 0.267 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.732 0.268 0.000
S82.5 Fracture of medial malleolus
0.732 0.268 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.731 0.269 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.730 0.270 0.000
Chapter XXII Codes for special purposes
0.729 0.271 0.000
M79.61 Pain in limb (Shoulder region)
0.729 0.271 0.000
B37 Candidiasis
0.728 0.272 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.724 0.276 0.000
F30-F39 Mood [affective] disorders
0.724 0.276 0.000
I49 Other cardiac arrhythmias
0.724 0.276 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.723 0.277 0.000
F80-F89 Disorders of psychological development
0.723 0.277 0.000
H61.9 Disorder of external ear, unspecified
0.723 0.277 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.723 0.277 0.000
T79.6 Traumatic ischaemia of muscle
0.722 0.278 0.000
M20.0 Deformity of finger(s)
0.722 0.278 0.000
A48 Other bacterial diseases, not elsewhere classified
0.721 0.278 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.721 0.279 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.720 0.280 0.000
R34 Anuria and oliguria
0.720 0.280 0.000
F02 Dementia in other diseases classified elsewhere
0.719 0.281 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.719 0.281 0.000
R57.2 Septic shock
0.718 0.282 0.000
F10.6 Amnesic syndrome
0.717 0.283 0.000
Y57 Other and unspecified drugs and medicaments
0.717 0.283 0.000
F10.4 Withdrawal state with delirium
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M22.4 Chondromalacia patellae
0.716 0.284 0.000
H90-H95 Other disorders of ear
0.716 0.284 0.000
M20.5 Other deformities of toe(s) (acquired)
0.713 0.287 0.000
T79.7 Traumatic subcutaneous emphysema
0.713 0.287 0.000
K65.8 Other peritonitis
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.710 0.290 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.710 0.290 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B65-B83 Helminthiases
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.709 0.290 0.000
E20-E35 Disorders of other endocrine glands
0.709 0.291 0.000
R68 Other general symptoms and signs
0.709 0.291 0.000
R25.3 Fasciculation
0.709 0.291 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.291 0.000
I95.8 Other hypotension
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
R27.0 Ataxia, unspecified
0.708 0.292 0.000
S82.6 Fracture of lateral malleolus
0.707 0.292 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.707 0.293 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.707 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.706 0.294 0.000
F05.8 Other delirium
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
I80 Phlebitis and thrombophlebitis
0.705 0.295 0.000
T92.1 Sequelae of fracture of arm
0.704 0.296 0.000
F20 Schizophrenia
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
A44 Bartonellosis
0.704 0.296 0.000
A43 Nocardiosis
0.704 0.296 0.000
A42 Actinomycosis
0.704 0.296 0.000
A39 Meningococcal infection
0.704 0.296 0.000
A37 Whooping cough
0.704 0.296 0.000
A36 Diphtheria
0.704 0.296 0.000
A32 Listeriosis
0.704 0.296 0.000
A31 Infection due to other mycobacteria
0.704 0.296 0.000
A30 Leprosy [Hansen's disease]
0.704 0.296 0.000
A38 Scarlet fever
0.704 0.296 0.000
A35 Other tetanus
0.704 0.296 0.000
A34 Obstetrical tetanus
0.704 0.296 0.000
A33 Tetanus neonatorum
0.704 0.296 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
S12 Fracture of neck
0.703 0.297 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.702 0.298 0.000
R39 Other symptoms and signs involving the urinary system
0.702 0.298 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.701 0.299 0.000
M76 Enthesopathies of lower limb, excluding foot
0.700 0.300 0.000
S10 Superficial injury of neck
0.699 0.301 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.699 0.301 0.000
R36 Urethral discharge
0.699 0.301 0.000
M71 Other bursopathies
0.699 0.301 0.000
K51.2 Ulcerative (chronic) proctitis
0.698 0.302 0.000
F99 Mental disorder, not otherwise specified
0.698 0.302 0.000
A41.4 Septicaemia due to anaerobes
0.698 0.302 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.698 0.302 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.697 0.303 0.000
T95 Sequelae of burns, corrosions and frostbite
0.697 0.303 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.697 0.303 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.697 0.303 0.000
T79.8 Other early complications of trauma
0.697 0.303 0.000
A40 Streptococcal septicaemia
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.696 0.303 0.000
F05.9 Delirium, unspecified
0.695 0.305 0.000
M79.66 Pain in limb (Lower leg)
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.694 0.306 0.000
H80-H83 Diseases of inner ear
0.693 0.307 0.000
B44 Aspergillosis
0.693 0.307 0.000
M66 Spontaneous rupture of synovium and tendon
0.693 0.307 0.000
M77.9 Enthesopathy, unspecified
0.693 0.307 0.000
M79.3 Panniculitis, unspecified
0.693 0.307 0.000
M89.8 Other specified disorders of bone
0.692 0.308 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.308 0.000
K51.4 Pseudopolyposis of colon
0.691 0.309 0.000
I33 Acute and subacute endocarditis
0.690 0.310 0.000
M79.5 Residual foreign body in soft tissue
0.689 0.310 0.000
I00-I02 Acute rheumatic fever
0.689 0.310 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.689 0.311 0.000
M80 Osteoporosis with pathological fracture
0.688 0.312 0.000
I44.7 Left bundle-branch block, unspecified
0.688 0.312 0.000
M43.0 Spondylolysis
0.688 0.312 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.687 0.313 0.000
F09 Unspecified organic or symptomatic mental disorder
0.687 0.313 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.687 0.313 0.000
F23 Acute and transient psychotic disorders
0.687 0.313 0.000
M24.2 Disorder of ligament
0.686 0.313 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.686 0.314 0.000
W50-W64 Exposure to animate mechanical forces
0.686 0.314 0.000
M22.3 Other derangements of patella
0.686 0.314 0.000
R25.2 Cramp and spasm
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.685 0.315 0.000
M42 Spinal osteochondrosis
0.684 0.316 0.000
M40 Kyphosis and lordosis
0.684 0.316 0.000
I44.0 Atrioventricular block, first degree
0.684 0.316 0.000
M24.0 Loose body in joint
0.684 0.316 0.000
F10.5 Psychotic disorder
0.684 0.316 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.684 0.316 0.000
S70-S79 Injuries to the hip and thigh
0.683 0.317 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.683 0.317 0.000
R61.9 Hyperhidrosis, unspecified
0.682 0.318 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.682 0.318 0.000
X50-X57 Overexertion, travel and privation
0.682 0.318 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.681 0.319 0.000
I05-I09 Chronic rheumatic heart diseases
0.680 0.320 0.000
S82.4 Fracture of fibula alone
0.680 0.320 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.679 0.321 0.000
R60.1 Generalised oedema
0.679 0.321 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.679 0.321 0.000
M43.1 Spondylolisthesis
0.677 0.323 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.677 0.323 0.000
F10.3 Withdrawal state
0.676 0.324 0.000
S99 Other and unspecified injuries of ankle and foot
0.675 0.325 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.675 0.325 0.000
M45-M49 Spondylopathies
0.675 0.325 0.000
K51.5 Mucosal proctocolitis
0.675 0.325 0.000
I95.0 Idiopathic hypotension
0.675 0.325 0.000
E70-E90 Metabolic disorders
0.674 0.326 0.000
S58 Traumatic amputation of forearm
0.672 0.328 0.000
S57 Crushing injury of forearm
0.672 0.328 0.000
S55 Injury of blood vessels at forearm level
0.672 0.328 0.000
S54 Injury of nerves at forearm level
0.672 0.328 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.672 0.328 0.000
S80 Superficial injury of lower leg
0.671 0.329 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.671 0.329 0.000
I38 Endocarditis, valve unspecified
0.670 0.330 0.000
M05-M14 Inflammatory polyarthropathies
0.670 0.330 0.000
S82.8 Fractures of other parts of lower leg
0.669 0.331 0.000
B25-B34 Other viral diseases
0.669 0.331 0.000
R53 Malaise and fatigue
0.669 0.331 0.000
F05.0 Delirium not superimposed on dementia, so described
0.668 0.332 0.000
S40-S49 Injuries to the shoulder and upper arm
0.668 0.332 0.000
Y95 Nosocomial condition
0.668 0.332 0.000
S86 Injury of muscle and tendon at lower leg level
0.668 0.332 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.667 0.333 0.000
S32 Fracture of lumbar spine and pelvis
0.667 0.333 0.000
M24.5 Contracture of joint
0.666 0.333 0.000
F60-F69 Disorders of adult personality and behaviour
0.666 0.334 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.666 0.334 0.000
M35 Other systemic involvement of connective tissue
0.666 0.334 0.000
K50.0 Crohn's disease of small intestine
0.665 0.335 0.000
S82.0 Fracture of patella
0.665 0.335 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.664 0.335 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.664 0.335 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.664 0.335 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.664 0.335 0.000
L89 Decubitus ulcer
0.664 0.336 0.000
T79.9 Unspecified early complication of trauma
0.664 0.336 0.000
T79.5 Traumatic anuria
0.664 0.336 0.000
T79.4 Traumatic shock
0.664 0.336 0.000
T79.2 Traumatic secondary and recurrent haemorrhage
0.664 0.336 0.000
T79.1 Fat embolism (traumatic)
0.664 0.336 0.000
T79.0 Air embolism (traumatic)
0.664 0.336 0.000
S60 Superficial injury of wrist and hand
0.664 0.336 0.000
M24.9 Joint derangement, unspecified
0.663 0.336 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.663 0.336 0.000
M24.7 Protrusio acetabuli
0.663 0.336 0.000
M24.6 Ankylosis of joint
0.663 0.336 0.000
M79.08 Rheumatism, unspecified (Other)
0.663 0.337 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.663 0.337 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.663 0.337 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.663 0.337 0.000
M79.04 Rheumatism, unspecified (Hand)
0.663 0.337 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.663 0.337 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.663 0.337 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.663 0.337 0.000
S90 Superficial injury of ankle and foot
0.663 0.337 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.663 0.337 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.662 0.338 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.661 0.339 0.000
I99 Other and unspecified disorders of circulatory system
0.661 0.339 0.000
I49.1 Atrial premature depolarisation
0.660 0.340 0.000
R46 Symptoms and signs involving appearance and behaviour
0.660 0.340 0.000
I46 Cardiac arrest
0.659 0.341 0.000
I95.9 Hypotension, unspecified
0.659 0.341 0.000
I37 Pulmonary valve disorders
0.659 0.341 0.000
S69 Other and unspecified injuries of wrist and hand
0.658 0.342 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.658 0.342 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.657 0.343 0.000
W07 Fall involving chair
0.657 0.343 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.657 0.343 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.657 0.343 0.000
Y59 Other and unspecified vaccines and biological substances
0.656 0.344 0.000
Y58 Bacterial vaccines
0.656 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.656 0.344 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.656 0.344 0.000
Y48 Anaesthetics and therapeutic gases
0.656 0.344 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.656 0.344 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.656 0.344 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.656 0.344 0.000
R56 Convulsions, not elsewhere classified
0.656 0.344 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.654 0.346 0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation
0.653 0.347 0.000
I49.9 Cardiac arrhythmia, unspecified
0.653 0.347 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.652 0.348 0.000
M79.68 Pain in limb (Other)
0.651 0.349 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.651 0.349 0.000
S65.5 Injury of blood vessel(s) of other finger
0.651 0.349 0.000
S67 Crushing injury of wrist and hand
0.650 0.350 0.000
M79.67 Pain in limb (Ankle and foot)
0.650 0.350 0.000
Q50-Q56 Congenital malformations of genital organs
0.649 0.350 0.000
S51.9 Open wound of forearm, part unspecified
0.649 0.351 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.649 0.351 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.648 0.352 0.000
M15-M19 Arthrosis
0.648 0.352 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.648 0.352 0.000
R81 Glycosuria
0.647 0.353 0.000
A49.0 Staphylococcal infection, unspecified
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.354 0.000
S00 Superficial injury of head
0.645 0.355 0.000
S82.30 Fracture of lower end of tibia (closed)
0.644 0.356 0.000
R45 Symptoms and signs involving emotional state
0.643 0.357 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.642 0.358 0.000
S88 Traumatic amputation of lower leg
0.642 0.358 0.000
S87 Crushing injury of lower leg
0.642 0.358 0.000
S85 Injury of blood vessels at lower leg level
0.642 0.358 0.000
S84 Injury of nerves at lower leg level
0.642 0.358 0.000
E27 Other disorders of adrenal gland
0.642 0.358 0.000
I73.8 Other specified peripheral vascular diseases
0.642 0.358 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.642 0.358 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.641 0.359 0.000
R82 Other abnormal findings in urine
0.641 0.359 0.000
V10-V19 Pedal cyclist injured in transport accident
0.640 0.360 0.000
B37.9 Candidiasis, unspecified
0.640 0.360 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.639 0.361 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.639 0.361 0.000
S82.50 Fracture of medial malleolus (closed)
0.639 0.361 0.000
S91 Open wound of ankle and foot
0.639 0.361 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.638 0.362 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.638 0.362 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.638 0.362 0.000
Y00 Assault by blunt object
0.637 0.363 0.000
F00 Dementia in Alzheimer's disease
0.637 0.363 0.000
Y43.1 Antineoplastic antimetabolites
0.636 0.364 0.000
M41.8 Other forms of scoliosis
0.634 0.365 0.000
M41.5 Other secondary scoliosis
0.634 0.365 0.000
M41.4 Neuromuscular scoliosis
0.634 0.365 0.000
M41.3 Thoracogenic scoliosis
0.634 0.365 0.000
M41.2 Other idiopathic scoliosis
0.634 0.365 0.000
M41.1 Juvenile idiopathic scoliosis
0.634 0.365 0.000
M41.0 Infantile idiopathic scoliosis
0.634 0.365 0.000
R29.6 Tendency to fall, not elsewhere classified
0.635 0.365 0.000
I95.1 Orthostatic hypotension
0.634 0.366 0.000
M22.1 Recurrent subluxation of patella
0.634 0.366 0.000
M22.9 Disorder of patella, unspecified
0.634 0.366 0.000
M22.0 Recurrent dislocation of patella
0.634 0.366 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.634 0.366 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.634 0.366 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.634 0.366 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.634 0.366 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.634 0.366 0.000
M79.7 Fibromyalgia
0.634 0.366 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.633 0.367 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.632 0.368 0.000
M20.3 Other deformity of hallux (acquired)
0.632 0.368 0.000
W22.2 School, other institution and public administrative area
0.632 0.368 0.000
H61.3 Acquired stenosis of external ear canal
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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