TreeWAS – Variant ID: rs74851542

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.998	0.002	0.000
K29 Gastritis and duodenitis	0.992	0.008	0.000
Z53 Persons encountering health services for specifie procedures, not carried out	0.990	0.010	0.000
Chapter XIV Diseases of the genitourinary system	0.983	0.017	0.000
K29.7 Gastritis, unspecified	0.979	0.021	0.000
Z53.8 Procedure not carried out for other reasons	0.978	0.022	0.000
Chapter V Mental and behavioural disorders	0.974	0.026	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.974	0.026	0.000
R50-R69 General symptoms and signs	0.972	0.028	0.000
K55-K64 Other diseases of intestines	0.962	0.038	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.946	0.054	0.000
K90-K93 Other diseases of the digestive system	0.944	0.056	0.000
Chapter II Neoplasms	0.937	0.063	0.000
Chapter X Diseases of the respiratory system	0.935	0.065	0.000
R30-R39 Symptoms and signs involving the urinary system	0.934	0.066	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.926	0.074	0.000
R55 Syncope and collapse	0.925	0.075	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.921	0.079	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.910	0.090	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.903	0.097	0.000
N17-N19 Renal failure	0.903	0.097	0.000
K22 Other diseases of oesophagus	0.900	0.100	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.899	0.101	0.000
K92 Other diseases of digestive system	0.894	0.106	0.000
K59 Other functional intestinal disorders	0.891	0.109	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.888	0.112	0.000
Z50 Care involving use of rehabilitation procedures	0.884	0.116	0.000
Z86 Personal history of certain other diseases	0.882	0.118	0.000
Chapter IX Diseases of the circulatory system	0.879	0.121	0.000
Z92 Personal history of medical treatment	0.878	0.122	0.000
Chapter XX External causes of morbidity and mortality	0.862	0.138	0.000
K20 Oesophagitis	0.860	0.140	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.855	0.145	0.000
K62 Other diseases of anus and rectum	0.852	0.148	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.852	0.148	0.000
K31 Other diseases of stomach and duodenum	0.845	0.155	0.000
Z72 Problems related to lifestyle	0.845	0.155	0.000
J30-J39 Other diseases of upper respiratory tract	0.844	0.156	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.843	0.157	0.000
K59.0 Constipation	0.841	0.159	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.838	0.162	0.000
K21 Gastro-oesophageal reflux disease	0.834	0.166	0.000
R33 Retention of urine	0.834	0.166	0.000
K30 Dyspepsia	0.831	0.169	0.000
Chapter I Certain infectious and parasitic diseases	0.829	0.171	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.828	0.172	0.000
N18 Chronic renal failure	0.827	0.173	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.824	0.176	0.000
Z53.9 Procedure not carried out, unspecified reason	0.822	0.178	0.000
K29.8 Duodenitis	0.821	0.179	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.821	0.179	0.000
N30-N39 Other diseases of urinary system	0.819	0.181	0.000
K29.5 Chronic gastritis, unspecified	0.818	0.182	0.000
D60-D64 Aplastic and other anaemias	0.810	0.190	0.000
F30-F39 Mood [affective] disorders	0.810	0.190	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.809	0.191	0.000
E65-E68 Obesity and other hyperalimentation	0.801	0.199	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.800	0.200	0.000
D10-D36 Benign neoplasms	0.799	0.200	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.799	0.201	0.000
Z72.0 Tobacco use	0.798	0.202	0.000
Z86.4 Personal history of psychoactive substance abuse	0.795	0.205	0.000
K25 Gastric ulcer	0.795	0.205	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.794	0.206	0.000
Z51 Other medical care	0.793	0.207	0.000
R07 Pain in throat and chest	0.792	0.208	0.000
R69 Unknown and unspecified causes of morbidity	0.792	0.208	0.000
Z13 Special screening examination for other diseases and disorders	0.790	0.210	0.000
K22.1 Ulcer of oesophagus	0.789	0.211	0.000
Z43 Attention to artificial openings	0.788	0.211	0.000
Z46 Fitting and adjustment of other devices	0.788	0.212	0.000
Z80 Family history of malignant neoplasm	0.787	0.213	0.000
R56 Convulsions, not elsewhere classified	0.786	0.214	0.000
Z45 Adjustment and management of implanted device	0.784	0.216	0.000
E10-E14 Diabetes mellitus	0.783	0.217	0.000
J09-J18 Influenza and pneumonia	0.779	0.221	0.000
I30-I52 Other forms of heart disease	0.778	0.222	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.777	0.223	0.000
N40-N51 Diseases of male genital organs	0.776	0.224	0.000
K26 Duodenal ulcer	0.774	0.226	0.000
R32 Unspecified urinary incontinence	0.774	0.226	0.000
F41 Other anxiety disorders	0.769	0.231	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.766	0.234	0.000
K62.1 Rectal polyp	0.763	0.237	0.000
N20-N23 Urolithiasis	0.762	0.238	0.000
Z90.5 Acquired absence of kidney	0.762	0.238	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.761	0.239	0.000
Z87 Personal history of other diseases and conditions	0.761	0.239	0.000
Z53.0 Procedure not carried out because of contraindication	0.760	0.240	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.756	0.244	0.000
J32 Chronic sinusitis	0.756	0.244	0.000
Z93 Artificial opening status	0.755	0.245	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.748	0.252	0.000
K92.0 Haematemesis	0.746	0.254	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.745	0.255	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.744	0.256	0.000
E00-E07 Disorders of thyroid gland	0.742	0.258	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.742	0.258	0.000
R59 Enlarged lymph nodes	0.739	0.261	0.000
D50-D53 Nutritional anaemias	0.739	0.261	0.000
R35 Polyuria	0.737	0.263	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.737	0.263	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.735	0.265	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.734	0.266	0.000
K22.2 Oesophageal obstruction	0.733	0.267	0.000
R07.4 Chest pain, unspecified	0.732	0.268	0.000
K92.1 Melaena	0.731	0.269	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.731	0.269	0.000
N18.3 Chronic kidney disease, stage 3	0.730	0.270	0.000
Z86.0 Personal history of other neoplasms	0.730	0.270	0.000
D64 Other anaemias	0.730	0.270	0.000
K90 Intestinal malabsorption	0.730	0.270	0.000
Chapter VI Diseases of the nervous system	0.728	0.272	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.728	0.272	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.727	0.272	0.000
J20-J22 Other acute lower respiratory infections	0.726	0.274	0.000
F10.2 Dependence syndrome	0.726	0.274	0.000
C15-C26 Malignant neoplasms of digestive organs	0.725	0.274	0.000
C50-C50 Malignant neoplasm of breast	0.724	0.276	0.000
R63 Symptoms and signs concerning food and fluid intake	0.722	0.278	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.721	0.279	0.000
R53 Malaise and fatigue	0.720	0.280	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.719	0.281	0.000
R06 Abnormalities of breathing	0.719	0.281	0.000
C44 Other malignant neoplasms of skin	0.718	0.282	0.000
K70-K77 Diseases of liver	0.717	0.283	0.000
K35-K38 Diseases of appendix	0.717	0.283	0.000
Chapter XXII Codes for special purposes	0.717	0.283	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.717	0.283	0.000
Z86.7 Personal history of diseases of the circulatory system	0.717	0.283	0.000
K28 Gastrojejunal ulcer	0.717	0.283	0.000
K27 Peptic ulcer, site unspecified	0.717	0.283	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.717	0.283	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.716	0.284	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.716	0.284	0.000
R47-R49 Symptoms and signs involving speech and voice	0.716	0.284	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.716	0.284	0.000
Z54 Convalescence	0.716	0.284	0.000
Z52 Donors of organs and tissues	0.716	0.284	0.000
Z49 Care involving dialysis	0.716	0.284	0.000
Z48 Other surgical follow-up care	0.716	0.284	0.000
Z44 Fitting and adjustment of external prosthetic device	0.716	0.284	0.000
Z42 Follow-up care involving plastic surgery	0.716	0.284	0.000
Z41 Procedures for purposes other than remedying health state	0.716	0.284	0.000
Z40 Prophylactic surgery	0.716	0.284	0.000
Chapter VIII Diseases of the ear and mastoid process	0.716	0.284	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.714	0.286	0.000
E66 Obesity	0.712	0.288	0.000
K29.9 Gastroduodenitis, unspecified	0.711	0.289	0.000
K29.4 Chronic atrophic gastritis	0.711	0.289	0.000
K29.3 Chronic superficial gastritis	0.711	0.289	0.000
K29.2 Alcoholic gastritis	0.711	0.289	0.000
K29.1 Other acute gastritis	0.711	0.289	0.000
K29.0 Acute haemorrhagic gastritis	0.711	0.289	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.710	0.290	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.710	0.290	0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.710	0.290	0.000
N17 Acute renal failure	0.708	0.292	0.000
K50-K52 Noninfective enteritis and colitis	0.706	0.294	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.706	0.294	0.000
Z50.1 Other physical therapy	0.705	0.295	0.000
N99-N99 Other disorders of the genitourinary system	0.705	0.295	0.000
N60-N64 Disorders of breast	0.705	0.295	0.000
N25-N29 Other disorders of kidney and ureter	0.705	0.295	0.000
N10-N16 Renal tubulo-interstitial diseases	0.705	0.295	0.000
N00-N08 Glomerular diseases	0.705	0.295	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.705	0.295	0.000
R50 Fever of unknown origin	0.704	0.296	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.702	0.298	0.000
N92 Excessive, frequent and irregular menstruation	0.700	0.300	0.000
F99-F99 Unspecified mental disorder	0.698	0.301	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.698	0.301	0.000
F80-F89 Disorders of psychological development	0.698	0.301	0.000
F70-F79 Mental retardation	0.698	0.301	0.000
F60-F69 Disorders of adult personality and behaviour	0.698	0.301	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.698	0.301	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.698	0.301	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.698	0.301	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.698	0.301	0.000
Z98 Other postsurgical states	0.698	0.301	0.000
Z97 Presence of other devices	0.698	0.301	0.000
Z94 Transplanted organ and tissue status	0.698	0.301	0.000
Z89 Acquired absence of limb	0.698	0.301	0.000
Z84 Family history of other conditions	0.698	0.301	0.000
Z83 Family history of other specific disorders	0.698	0.301	0.000
Z81 Family history of mental and behavioural disorders	0.698	0.301	0.000
N18.9 Chronic renal failure, unspecified	0.698	0.302	0.000
R68 Other general symptoms and signs	0.697	0.303	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.697	0.303	0.000
R62 Lack of expected normal physiological development	0.697	0.303	0.000
R61 Hyperhidrosis	0.697	0.303	0.000
R60 Oedema, not elsewhere classified	0.697	0.303	0.000
R57 Shock, not elsewhere classified	0.697	0.303	0.000
R52 Pain, not elsewhere classified	0.697	0.303	0.000
R64 Cachexia	0.697	0.303	0.000
R58 Haemorrhage, not elsewhere classified	0.697	0.303	0.000
R54 Senility	0.697	0.303	0.000
K57 Diverticular disease of intestine	0.694	0.306	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.694	0.306	0.000
Chapter VII Diseases of the eye and adnexa	0.694	0.306	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.693	0.307	0.000
J32.9 Chronic sinusitis, unspecified	0.693	0.307	0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.692	0.308	0.000
R39 Other symptoms and signs involving the urinary system	0.692	0.308	0.000
F32 Depressive episode	0.692	0.308	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.690	0.310	0.000
K61 Abscess of anal and rectal regions	0.690	0.310	0.000
K60 Fissure and fistula of anal and rectal regions	0.690	0.310	0.000
K55 Vascular disorders of intestine	0.690	0.310	0.000
K31.7 Polyp of stomach and duodenum	0.687	0.313	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.686	0.314	0.000
K62.8 Other specified diseases of anus and rectum	0.686	0.314	0.000
K65-K67 Diseases of peritoneum	0.685	0.315	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.683	0.317	0.000
R00 Abnormalities of heart beat	0.682	0.318	0.000
Z12 Special screening examination for neoplasms	0.682	0.318	0.000
N32 Other disorders of bladder	0.680	0.320	0.000
R18 Ascites	0.679	0.321	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.678	0.321	0.000
Z10 Routine general health check-up of defined subpopulation	0.678	0.321	0.000
Z04 Examination and observation for other reasons	0.678	0.321	0.000
Z02 Examination and encounter for administrative purposes	0.678	0.321	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.678	0.321	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.678	0.321	0.000
K31.8 Other specified diseases of stomach and duodenum	0.678	0.322	0.000
F10.1 Harmful use	0.677	0.323	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.677	0.323	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.677	0.323	0.000
F41.9 Anxiety disorder, unspecified	0.677	0.323	0.000
Z90.1 Acquired absence of breast(s)	0.673	0.327	0.000
D64.9 Anaemia, unspecified	0.672	0.327	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.672	0.328	0.000
D00-D09 In situ neoplasms	0.672	0.328	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.672	0.328	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.672	0.328	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.672	0.328	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.672	0.328	0.000
C64-C68 Malignant neoplasms of urinary tract	0.672	0.328	0.000
C51-C58 Malignant neoplasms of female genital organs	0.672	0.328	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.672	0.328	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.672	0.328	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.672	0.328	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.672	0.328	0.000
K29.6 Other gastritis	0.670	0.330	0.000
J95-J99 Other diseases of the respiratory system	0.670	0.330	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.670	0.330	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.670	0.330	0.000
J60-J70 Lung diseases due to external agents	0.670	0.330	0.000
J00-J06 Acute upper respiratory infections	0.670	0.330	0.000
R30 Pain associated with micturition	0.670	0.330	0.000
R36 Urethral discharge	0.670	0.330	0.000
R34 Anuria and oliguria	0.670	0.330	0.000
N95 Menopausal and other perimenopausal disorders	0.670	0.330	0.000
J34 Other disorders of nose and nasal sinuses	0.667	0.333	0.000
J18 Pneumonia, organism unspecified	0.667	0.333	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.664	0.335	0.000
E50-E64 Other nutritional deficiencies	0.664	0.336	0.000
E40-E46 Malnutrition	0.664	0.336	0.000
E20-E35 Disorders of other endocrine glands	0.664	0.336	0.000
Z51.3 Blood transfusion without reported diagnosis	0.664	0.336	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.663	0.337	0.000
D80-D89 Certain disorders involving the immune mechanism	0.661	0.339	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.661	0.339	0.000
D55-D59 Haemolytic anaemias	0.661	0.339	0.000
N39 Other disorders of urinary system	0.660	0.340	0.000
K58 Irritable bowel syndrome	0.659	0.341	0.000
W00-W19 Falls	0.658	0.342	0.000
B35-B49 Mycoses	0.657	0.342	0.000
J40-J47 Chronic lower respiratory diseases	0.657	0.343	0.000
J90-J94 Other diseases of pleura	0.657	0.343	0.000
R26 Abnormalities of gait and mobility	0.656	0.344	0.000
R14 Flatulence and related conditions	0.655	0.345	0.000
K01 Embedded and impacted teeth	0.653	0.346	0.000
K63 Other diseases of intestine	0.653	0.347	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.653	0.347	0.000
R56.8 Other and unspecified convulsions	0.653	0.347	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.653	0.347	0.000
Z47 Other orthopaedic follow-up care	0.652	0.347	0.000
K22.7 Barrett's oesophagus	0.652	0.348	0.000
Z76 Persons encountering health services in other circumstances	0.652	0.348	0.000
Z75 Problems related to medical facilities and other health care	0.652	0.348	0.000
Z74 Problems related to care-provider dependency	0.652	0.348	0.000
Z73 Problems related to life-management difficulty	0.652	0.348	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.652	0.348	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.652	0.348	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.651	0.349	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.650	0.350	0.000
R04 Haemorrhage from respiratory passages	0.650	0.350	0.000
K02 Dental caries	0.649	0.351	0.000
Z13.9 Special screening examination, unspecified	0.648	0.352	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.648	0.352	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.648	0.352	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.647	0.353	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.647	0.353	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.647	0.353	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.647	0.353	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.647	0.353	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.647	0.353	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.647	0.353	0.000
F11 Mental and behavioural disorders due to use of opioids	0.647	0.353	0.000
N19 Unspecified renal failure	0.647	0.353	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.647	0.353	0.000
K22.9 Disease of oesophagus, unspecified	0.645	0.354	0.000
K22.8 Other specified diseases of oesophagus	0.645	0.354	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.645	0.354	0.000
K22.5 Diverticulum of oesophagus, acquired	0.645	0.354	0.000
K22.4 Dyskinesia of oesophagus	0.645	0.354	0.000
K22.3 Perforation of oesophagus	0.645	0.354	0.000
K22.0 Achalasia of cardia	0.645	0.354	0.000
Z51.2 Other chemotherapy	0.646	0.354	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.645	0.355	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.645	0.355	0.000
R01 Cardiac murmurs and other cardiac sounds	0.645	0.355	0.000
R02 Gangrene, not elsewhere classified	0.645	0.355	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.643	0.356	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.643	0.357	0.000
I60-I69 Cerebrovascular diseases	0.643	0.357	0.000
Z87.0 Personal history of diseases of the respiratory system	0.642	0.358	0.000
I31 Other diseases of pericardium	0.642	0.358	0.000
K92.9 Disease of digestive system, unspecified	0.641	0.359	0.000
K92.8 Other specified diseases of digestive system	0.641	0.359	0.000
K40-K46 Hernia	0.640	0.360	0.001
R31 Unspecified haematuria	0.640	0.360	0.000
K59.9 Functional intestinal disorder, unspecified	0.639	0.361	0.000
K59.8 Other specified functional intestinal disorders	0.639	0.361	0.000
K59.4 Anal spasm	0.639	0.361	0.000
K59.3 Megacolon, not elsewhere classified	0.639	0.361	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.639	0.361	0.000
K59.1 Functional diarrhoea	0.639	0.361	0.000
Z43.2 Attention to ileostomy	0.638	0.362	0.000
I50 Heart failure	0.638	0.362	0.000
Z46.6 Fitting and adjustment of urinary device	0.638	0.362	0.000
Z90.8 Acquired absence of other organs	0.637	0.363	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.637	0.363	0.000
Z90.3 Acquired absence of part of stomach	0.637	0.363	0.000
Z90.2 Acquired absence of lung [part of]	0.637	0.363	0.000
Z90.0 Acquired absence of part of head and neck	0.637	0.363	0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.636	0.364	0.000
Z85 Personal history of malignant neoplasm	0.635	0.365	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.635	0.365	0.000
Z50.8 Care involving use of rehabilitation procedures	0.634	0.366	0.000
Z50.6 Orthoptic training	0.634	0.366	0.000
Z50.5 Speech therapy	0.634	0.366	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.634	0.366	0.000
Z50.3 Drug rehabilitation	0.634	0.366	0.000
Z50.2 Alcohol rehabilitation	0.634	0.366	0.000
Z50.0 Cardiac rehabilitation	0.634	0.366	0.000
E10 Insulin-dependent diabetes mellitus	0.633	0.367	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.632	0.367	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.632	0.367	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.632	0.367	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.631	0.369	0.000
I05-I09 Chronic rheumatic heart diseases	0.630	0.370	0.000
I00-I02 Acute rheumatic fever	0.630	0.370	0.000
L60-L75 Disorders of skin appendages	0.630	0.370	0.000
Z92.9 Personal history of medical treatment, unspecified	0.630	0.370	0.000
Z92.8 Personal history of other medical treatment	0.630	0.370	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.630	0.370	0.000
Z92.5 Personal history of rehabilitation measures	0.630	0.370	0.000
Z92.0 Personal history of contraception	0.630	0.370	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.628	0.371	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.628	0.372	0.000
N40 Hyperplasia of prostate	0.628	0.372	0.000
A00-A09 Intestinal infectious diseases	0.625	0.374	0.000
F41.2 Mixed anxiety and depressive disorder	0.625	0.375	0.000
I73 Other peripheral vascular diseases	0.625	0.375	0.000
B95-B98 Bacterial, viral and other infectious agents	0.624	0.376	0.000
E66.9 Obesity, unspecified	0.623	0.377	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.622	0.378	0.000
D17 Benign lipomatous neoplasm	0.619	0.381	0.000
E11 Non-insulin-dependent diabetes mellitus	0.619	0.381	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.619	0.381	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.618	0.382	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.618	0.382	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.618	0.382	0.000
Y35-Y36 Legal intervention and operations of war	0.618	0.382	0.000
Y10-Y34 Event of undetermined intent	0.618	0.382	0.000
Y00-Y09 Assault	0.618	0.382	0.000
X85-X99 Assault	0.618	0.382	0.000
X60-X84 Intentional self-harm	0.618	0.382	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.618	0.382	0.000
X50-X57 Overexertion, travel and privation	0.618	0.382	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.618	0.382	0.000
X30-X39 Exposure to forces of nature	0.618	0.382	0.000
X20-X29 Contact with venomous animals and plants	0.618	0.382	0.000
X10-X19 Contact with heat and hot substances	0.618	0.382	0.000
X00-X09 Exposure to smoke, fire and flames	0.618	0.382	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.618	0.382	0.000
W75-W84 Other accidental threats to breathing	0.618	0.382	0.000
W65-W74 Accidental drowning and submersion	0.618	0.382	0.000
W50-W64 Exposure to animate mechanical forces	0.618	0.382	0.000
W20-W49 Exposure to inanimate mechanical forces	0.618	0.382	0.000
V98-V99 Other and unspecified transport accidents	0.618	0.382	0.000
V95-V97 Air and space transport accidents	0.618	0.382	0.000
V90-V94 Water transport accidents	0.618	0.382	0.000
V80-V89 Other land transport accidents	0.618	0.382	0.000
V70-V79 Bus occupant injured in transport accident	0.618	0.382	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.618	0.382	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.618	0.382	0.000
V40-V49 Car occupant injured in transport accident	0.618	0.382	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.618	0.382	0.000
V20-V29 Motorcycle rider injured in transport accident	0.618	0.382	0.000
V10-V19 Pedal cyclist injured in transport accident	0.618	0.382	0.000
V01-V09 Pedestrian injured in transport accident	0.618	0.382	0.000
N80 Endometriosis	0.614	0.386	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.614	0.386	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.613	0.386	0.000
R05 Cough	0.613	0.387	0.000
F48 Other neurotic disorders	0.613	0.387	0.000
F45 Somatoform disorders	0.613	0.387	0.000
F44 Dissociative [conversion] disorders	0.613	0.387	0.000
F43 Reaction to severe stress, and adjustment disorders	0.613	0.387	0.000
F42 Obsessive-compulsive disorder	0.613	0.387	0.000
F40 Phobic anxiety disorders	0.613	0.387	0.000
K08 Other disorders of teeth and supporting structures	0.613	0.387	0.000
J18.9 Pneumonia, unspecified	0.613	0.387	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.612	0.388	0.000
K62.9 Disease of anus and rectum, unspecified	0.611	0.389	0.000
K62.7 Radiation proctitis	0.611	0.389	0.000
K62.6 Ulcer of anus and rectum	0.611	0.389	0.000
K62.4 Stenosis of anus and rectum	0.611	0.389	0.000
K62.3 Rectal prolapse	0.611	0.389	0.000
K62.2 Anal prolapse	0.611	0.389	0.000
K62.0 Anal polyp	0.611	0.389	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.611	0.389	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.611	0.389	0.000
Z09.4 Follow-up examination after treatment of fracture	0.611	0.389	0.000
Z09.3 Follow-up examination after psychotherapy	0.611	0.389	0.000
Z09.1 Follow-up examination after radiotherapy for other conditions	0.611	0.389	0.000
F17.2 Dependence syndrome	0.611	0.389	0.000
Z92.3 Personal history of irradiation	0.611	0.389	0.000
Z72.1 Alcohol use	0.610	0.390	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.610	0.390	0.000
E03 Other hypothyroidism	0.609	0.390	0.000
M70-M79 Other soft tissue disorders	0.609	0.391	0.000
K56.6 Other and unspecified intestinal obstruction	0.608	0.391	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.608	0.392	0.000
D50 Iron deficiency anaemia	0.608	0.392	0.000
R51 Headache	0.607	0.393	0.000
F32.9 Depressive episode, unspecified	0.607	0.393	0.000
A30-A49 Other bacterial diseases	0.607	0.393	0.000
Z90.7 Acquired absence of genital organ(s)	0.607	0.393	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.606	0.394	0.000
K31.6 Fistula of stomach and duodenum	0.606	0.394	0.000
K31.5 Obstruction of duodenum	0.606	0.394	0.000
K31.4 Gastric diverticulum	0.606	0.394	0.000
K31.3 Pylorospasm, not elsewhere classified	0.606	0.394	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.606	0.394	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.606	0.394	0.000
K31.0 Acute dilatation of stomach	0.606	0.394	0.000
Z72.9 Problem related to lifestyle, unspecified	0.606	0.394	0.000
Z72.8 Other problems related to lifestyle	0.606	0.394	0.000
Z72.6 Gambling and betting	0.606	0.394	0.000
Z72.5 High-risk sexual behaviour	0.606	0.394	0.000
Z72.4 Inappropriate diet and eating habits	0.606	0.394	0.000
Z72.3 Lack of physical exercise	0.606	0.394	0.000
Z72.2 Drug use	0.606	0.394	0.000
J39 Other diseases of upper respiratory tract	0.605	0.395	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.605	0.395	0.000
J37 Chronic laryngitis and laryngotracheitis	0.605	0.395	0.000
J35 Chronic diseases of tonsils and adenoids	0.605	0.395	0.000
J33 Nasal polyp	0.605	0.395	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.605	0.395	0.000
J30 Vasomotor and allergic rhinitis	0.605	0.395	0.000
J36 Peritonsillar abscess	0.605	0.395	0.000
N98 Complications associated with artificial fertilisation	0.604	0.396	0.000
N97 Female infertility	0.604	0.396	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.604	0.396	0.000
N93 Other abnormal uterine and vaginal bleeding	0.604	0.396	0.000
N91 Absent, scanty and rare menstruation	0.604	0.396	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.604	0.396	0.000
N89 Other noninflammatory disorders of vagina	0.604	0.396	0.000
N88 Other noninflammatory disorders of cervix uteri	0.604	0.396	0.000
N87 Dysplasia of cervix uteri	0.604	0.396	0.000
N82 Fistulae involving female genital tract	0.604	0.396	0.000
N96 Habitual aborter	0.604	0.396	0.000
N86 Erosion and ectropion of cervix uteri	0.604	0.396	0.000
N20 Calculus of kidney and ureter	0.604	0.396	0.000
N84 Polyp of female genital tract	0.602	0.398	0.000
L50-L54 Urticaria and erythema	0.601	0.399	0.000
L40-L45 Papulosquamous disorders	0.601	0.399	0.000
L20-L30 Dermatitis and eczema	0.601	0.399	0.000
L10-L14 Bullous disorders	0.601	0.399	0.000
Z96 Presence of other functional implants	0.600	0.400	0.000
C44.1 Skin of eyelid, including canthus	0.599	0.401	0.000
D70 Agranulocytosis	0.599	0.401	0.000
Z93.2 Ileostomy status	0.598	0.402	0.000
R12 Heartburn	0.597	0.403	0.000
B99-B99 Other infectious diseases	0.594	0.406	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.594	0.406	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.594	0.406	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations