TreeWAS – Variant ID: rs74907094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
J45.9 Asthma, unspecified	0.995	0.005	0.000
J45 Asthma	0.995	0.005	0.000
J40-J47 Chronic lower respiratory diseases	0.995	0.005	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.994	0.006	0.000
Chapter VI Diseases of the nervous system	0.993	0.007	0.000
O60-O75 Complications of labour and delivery	0.992	0.008	0.000
M15-M19 Arthrosis	0.987	0.013	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.984	0.016	0.000
J30-J39 Other diseases of upper respiratory tract	0.984	0.016	0.000
M05-M14 Inflammatory polyarthropathies	0.982	0.018	0.000
Chapter XX External causes of morbidity and mortality	0.974	0.026	0.000
O63 Long labour	0.965	0.035	0.000
J34 Other disorders of nose and nasal sinuses	0.963	0.037	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.957	0.043	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.953	0.047	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.952	0.048	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.950	0.050	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.948	0.052	0.000
M80-M85 Disorders of bone density and structure	0.947	0.053	0.000
M20-M25 Other joint disorders	0.947	0.053	0.000
M19 Other arthrosis	0.945	0.055	0.000
M13 Other arthritis	0.942	0.058	0.000
O63.1 Prolonged second stage (of labour)	0.937	0.063	0.000
S40-S49 Injuries to the shoulder and upper arm	0.936	0.064	0.000
O20 Haemorrhage in early pregnancy	0.936	0.064	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.934	0.066	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.934	0.066	0.000
Chapter IX Diseases of the circulatory system	0.931	0.069	0.000
I73 Other peripheral vascular diseases	0.929	0.071	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.927	0.073	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.922	0.078	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.917	0.083	0.000
S60-S69 Injuries to the wrist and hand	0.915	0.085	0.000
G35 Multiple sclerosis	0.912	0.088	0.000
I73.0 Raynaud's syndrome	0.911	0.089	0.000
E10-E14 Diabetes mellitus	0.909	0.091	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.909	0.091	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.906	0.094	0.000
M16 Coxarthrosis [arthrosis of hip]	0.904	0.096	0.000
M22 Disorders of patella	0.902	0.098	0.000
I74 Arterial embolism and thrombosis	0.898	0.102	0.000
E11 Non-insulin-dependent diabetes mellitus	0.897	0.103	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.893	0.107	0.000
O36 Maternal care for other known or suspected foetal problems	0.892	0.108	0.000
Chapter I Certain infectious and parasitic diseases	0.892	0.108	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.891	0.109	0.000
M13.9 Arthritis, unspecified	0.889	0.111	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.885	0.115	0.000
G90-G99 Other disorders of the nervous system	0.883	0.117	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.880	0.120	0.000
M81 Osteoporosis without pathological fracture	0.877	0.123	0.000
O62 Abnormalities of forces of labour	0.877	0.123	0.000
M19.9 Arthrosis, unspecified	0.874	0.126	0.000
M25 Other joint disorders, not elsewhere classified	0.872	0.128	0.000
M10 Gout	0.872	0.128	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.872	0.128	0.000
O23 Infections of genito-urinary tract in pregnancy	0.871	0.129	0.000
O70 Perineal laceration during delivery	0.870	0.130	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.868	0.132	0.000
D70 Agranulocytosis	0.868	0.132	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.867	0.133	0.000
T87 Complications peculiar to reattachment and amputation	0.866	0.134	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.864	0.136	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.861	0.139	0.000
Y83.3 Surgical operation with formation of external stoma	0.861	0.139	0.000
S80-S89 Injuries to the knee and lower leg	0.857	0.143	0.000
G20-G26 Extrapyramidal and movement disorders	0.855	0.145	0.000
J30 Vasomotor and allergic rhinitis	0.850	0.150	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.850	0.150	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.847	0.153	0.000
I73.9 Peripheral vascular disease, unspecified	0.845	0.155	0.000
O80-O84 Delivery	0.845	0.155	0.000
M86-M90 Other osteopathies	0.843	0.157	0.000
Y00-Y09 Assault	0.842	0.158	0.000
M22.2 Patellofemoral disorders	0.842	0.158	0.000
M07 Psoriatic and enteropathic arthropathies	0.840	0.160	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.837	0.163	0.000
T86 Failure and rejection of transplanted organs and tissues	0.833	0.167	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.830	0.170	0.000
S43.0 Dislocation of shoulder joint	0.830	0.170	0.000
S10-S19 Injuries to the neck	0.830	0.170	0.000
O24 Diabetes mellitus in pregnancy	0.829	0.171	0.000
M81.9 Osteoporosis, unspecified	0.829	0.171	0.000
I74.5 Embolism and thrombosis of iliac artery	0.829	0.171	0.000
G62 Other polyneuropathies	0.828	0.172	0.000
E11.5 With peripheral circulatory complications	0.827	0.173	0.000
O63.0 Prolonged first stage (of labour)	0.826	0.174	0.000
G70-G73 Diseases of myoneural junction and muscle	0.825	0.175	0.000
M19.0 Primary arthrosis of other joints	0.823	0.177	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.817	0.183	0.000
M16.0 Primary coxarthrosis, bilateral	0.817	0.183	0.000
J81 Pulmonary oedema	0.815	0.185	0.000
M34 Systemic sclerosis	0.815	0.185	0.000
J34.2 Deviated nasal septum	0.814	0.186	0.000
J32 Chronic sinusitis	0.814	0.186	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.813	0.187	0.000
M91-M94 Chondropathies	0.810	0.190	0.000
O30 Multiple gestation	0.802	0.198	0.000
E70-E90 Metabolic disorders	0.801	0.199	0.000
J33 Nasal polyp	0.801	0.199	0.000
M13.0 Polyarthritis, unspecified	0.801	0.199	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.800	0.200	0.000
E14 Unspecified diabetes mellitus	0.798	0.202	0.000
O21 Excessive vomiting in pregnancy	0.797	0.203	0.000
O00-O08 Pregnancy with abortive outcome	0.795	0.205	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.794	0.206	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.794	0.206	0.000
I60-I69 Cerebrovascular diseases	0.794	0.206	0.000
M10.9 Gout, unspecified	0.793	0.207	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.793	0.207	0.000
O48 Prolonged pregnancy	0.792	0.208	0.000
O70.0 First degree perineal laceration during delivery	0.791	0.209	0.000
T42.4 Benzodiazepines	0.790	0.210	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.790	0.210	0.000
X60-X84 Intentional self-harm	0.790	0.210	0.000
D72 Other disorders of white blood cells	0.790	0.210	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.787	0.213	0.000
A00-A09 Intestinal infectious diseases	0.786	0.214	0.000
Y83.5 Amputation of limb(s)	0.785	0.215	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.784	0.216	0.000
O70.9 Perineal laceration during delivery, unspecified	0.782	0.218	0.000
O36.6 Maternal care for excessive foetal growth	0.782	0.218	0.000
M24 Other specific joint derangements	0.781	0.219	0.000
O36.5 Maternal care for poor foetal growth	0.780	0.220	0.000
T81 Complications of procedures, not elsewhere classified	0.780	0.220	0.000
M16.7 Other secondary coxarthrosis	0.778	0.222	0.000
M82 Osteoporosis in diseases classified elsewhere	0.776	0.224	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.775	0.225	0.000
M21 Other acquired deformities of limbs	0.774	0.226	0.000
J39 Other diseases of upper respiratory tract	0.774	0.226	0.000
E11.9 Without complications	0.774	0.226	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.774	0.226	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.773	0.227	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.772	0.227	0.000
J00-J06 Acute upper respiratory infections	0.772	0.228	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.771	0.229	0.000
J45.0 Predominantly allergic asthma	0.769	0.231	0.000
O85-O92 Complications predominantly related to the puerperium	0.768	0.232	0.000
G62.9 Polyneuropathy, unspecified	0.767	0.233	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.766	0.234	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.765	0.235	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.764	0.235	0.000
S61 Open wound of wrist and hand	0.764	0.236	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.763	0.237	0.000
O23.5 Infections of the genital tract in pregnancy	0.761	0.239	0.000
J95-J99 Other diseases of the respiratory system	0.761	0.239	0.000
J85 Abscess of lung and mediastinum	0.761	0.239	0.000
S70-S79 Injuries to the hip and thigh	0.760	0.240	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.758	0.242	0.000
I72 Other aneurysm	0.756	0.244	0.000
T00-T07 Injuries involving multiple body regions	0.756	0.244	0.000
J90-J94 Other diseases of pleura	0.755	0.245	0.000
E11.4 With neurological complications	0.755	0.245	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.754	0.246	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.752	0.248	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.751	0.249	0.000
M25.3 Other instability of joint	0.749	0.251	0.000
Y04 Assault by bodily force	0.748	0.252	0.000
Chapter V Mental and behavioural disorders	0.748	0.252	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.747	0.253	0.000
M40-M43 Deforming dorsopathies	0.747	0.253	0.000
M19.2 Other secondary arthrosis	0.747	0.253	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.746	0.254	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.745	0.255	0.000
M22.4 Chondromalacia patellae	0.744	0.256	0.000
M17 Gonarthrosis [arthrosis of knee]	0.743	0.257	0.000
M25.9 Joint disorder, unspecified	0.742	0.258	0.000
T92 Sequelae of injuries of upper limb	0.742	0.258	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.742	0.258	0.000
I74.8 Embolism and thrombosis of other arteries	0.741	0.259	0.000
O43 Placental disorders	0.741	0.259	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.739	0.261	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.739	0.261	0.000
M07.3 Other psoriatic arthropathies	0.739	0.261	0.000
J40 Bronchitis, not specified as acute or chronic	0.738	0.262	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.737	0.263	0.000
M18 Arthrosis of first carpometacarpal joint	0.737	0.263	0.000
G24 Dystonia	0.737	0.263	0.000
J93 Pneumothorax	0.736	0.264	0.000
M85 Other disorders of bone density and structure	0.736	0.264	0.000
D68 Other coagulation defects	0.735	0.265	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.735	0.265	0.000
J80 Adult respiratory distress syndrome	0.735	0.265	0.000
M80 Osteoporosis with pathological fracture	0.735	0.265	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.734	0.266	0.000
J20-J22 Other acute lower respiratory infections	0.733	0.267	0.000
E11.3 With ophthalmic complications	0.733	0.267	0.000
T87.6 Other and unspecified complications of amputation stump	0.732	0.268	0.000
S86 Injury of muscle and tendon at lower leg level	0.731	0.269	0.000
O20.0 Threatened abortion	0.731	0.269	0.000
D60-D64 Aplastic and other anaemias	0.731	0.269	0.000
I73.8 Other specified peripheral vascular diseases	0.730	0.270	0.000
M60-M63 Disorders of muscles	0.730	0.270	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.730	0.270	0.000
I77 Other disorders of arteries and arterioles	0.730	0.270	0.000
J32.9 Chronic sinusitis, unspecified	0.729	0.271	0.000
S64 Injury of nerves at wrist and hand level	0.729	0.271	0.000
S42 Fracture of shoulder and upper arm	0.727	0.273	0.000
G90 Disorders of autonomic nervous system	0.726	0.274	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.726	0.274	0.000
A30-A49 Other bacterial diseases	0.726	0.274	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.725	0.275	0.000
E11.2 With renal complications	0.722	0.278	0.000
J93.9 Pneumothorax, unspecified	0.721	0.279	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.720	0.280	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.720	0.280	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.719	0.281	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.719	0.281	0.000
J86 Pyothorax	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
M00-M03 Infectious arthropathies	0.717	0.283	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
Y83.4 Other reconstructive surgery	0.717	0.283	0.000
E87.5 Hyperkalaemia	0.717	0.283	0.000
G37 Other demyelinating diseases of central nervous system	0.716	0.283	0.000
T66-T78 Other and unspecified effects of external causes	0.716	0.284	0.000
S67 Crushing injury of wrist and hand	0.716	0.284	0.000
J46 Status asthmaticus	0.715	0.285	0.000
J30.1 Allergic rhinitis due to pollen	0.715	0.285	0.000
J45.8 Mixed asthma	0.713	0.286	0.000
J45.1 Nonallergic asthma	0.713	0.286	0.000
J41 Simple and mucopurulent chronic bronchitis	0.713	0.286	0.000
S90-S99 Injuries to the ankle and foot	0.713	0.287	0.000
V20-V29 Motorcycle rider injured in transport accident	0.713	0.287	0.000
T88.4 Failed or difficult intubation	0.712	0.288	0.000
M25.8 Other specified joint disorders	0.712	0.288	0.000
I70 Atherosclerosis	0.712	0.288	0.000
O74 Complications of anaesthesia during labour and delivery	0.711	0.288	0.000
O71 Other obstetric trauma	0.711	0.288	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.711	0.288	0.000
O61 Failed induction of labour	0.711	0.288	0.000
O60 Preterm delivery	0.711	0.288	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.711	0.289	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.710	0.290	0.000
O44 Placenta praevia	0.710	0.290	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.709	0.291	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.709	0.291	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.709	0.291	0.000
V40-V49 Car occupant injured in transport accident	0.709	0.291	0.000
M15 Polyarthrosis	0.707	0.293	0.000
M16.5 Other posttraumatic coxarthrosis	0.706	0.294	0.000
O29 Complications of anaesthesia during pregnancy	0.705	0.295	0.000
O28 Abnormal findings on antenatal screening of mother	0.705	0.295	0.000
O22 Venous complications in pregnancy	0.705	0.295	0.000
O25 Malnutrition in pregnancy	0.705	0.295	0.000
J37 Chronic laryngitis and laryngotracheitis	0.705	0.295	0.000
J42 Unspecified chronic bronchitis	0.705	0.295	0.000
J30.3 Other allergic rhinitis	0.704	0.296	0.000
M12 Other specific arthropathies	0.704	0.296	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.704	0.296	0.000
M08 Juvenile arthritis	0.704	0.296	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.704	0.296	0.000
O73 Retained placenta and membranes, without haemorrhage	0.703	0.296	0.000
G30-G32 Other degenerative diseases of the nervous system	0.703	0.297	0.000
F30-F39 Mood [affective] disorders	0.701	0.299	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.700	0.300	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.700	0.300	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.699	0.301	0.000
O75.8 Other specified complications of labour and delivery	0.699	0.301	0.000
Y35-Y36 Legal intervention and operations of war	0.698	0.301	0.000
Y10-Y34 Event of undetermined intent	0.698	0.301	0.000
X85-X99 Assault	0.698	0.301	0.000
X50-X57 Overexertion, travel and privation	0.698	0.301	0.000
X30-X39 Exposure to forces of nature	0.698	0.301	0.000
X10-X19 Contact with heat and hot substances	0.698	0.301	0.000
X00-X09 Exposure to smoke, fire and flames	0.698	0.301	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.698	0.301	0.000
W75-W84 Other accidental threats to breathing	0.698	0.301	0.000
W65-W74 Accidental drowning and submersion	0.698	0.301	0.000
V98-V99 Other and unspecified transport accidents	0.698	0.301	0.000
V95-V97 Air and space transport accidents	0.698	0.301	0.000
V90-V94 Water transport accidents	0.698	0.301	0.000
V70-V79 Bus occupant injured in transport accident	0.698	0.301	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.698	0.301	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.698	0.301	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.698	0.301	0.000
V01-V09 Pedestrian injured in transport accident	0.698	0.301	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.698	0.302	0.000
T87.4 Infection of amputation stump	0.698	0.302	0.000
Q00-Q07 Congenital malformations of the nervous system	0.698	0.302	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.698	0.302	0.000
W50-W64 Exposure to animate mechanical forces	0.697	0.303	0.000
M13.93 Arthritis, unspecified (Forearm)	0.697	0.303	0.000
D75 Other diseases of blood and blood-forming organs	0.696	0.304	0.000
X20-X29 Contact with venomous animals and plants	0.696	0.304	0.000
O41 Other disorders of amniotic fluid and membranes	0.696	0.304	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.695	0.305	0.000
D72.8 Other specified disorders of white blood cells	0.695	0.305	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.695	0.305	0.000
M90 Osteopathies in diseases classified elsewhere	0.694	0.306	0.000
O30.0 Twin pregnancy	0.694	0.306	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.693	0.307	0.000
O80 Single spontaneous delivery	0.693	0.307	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.692	0.308	0.000
D68.2 Hereditary deficiency of other clotting factors	0.692	0.308	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.692	0.308	0.000
E14.9 Without complications	0.691	0.309	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.691	0.309	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.691	0.309	0.000
S68 Traumatic amputation of wrist and hand	0.691	0.309	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.690	0.310	0.000
M16.3 Other dysplastic coxarthrosis	0.690	0.310	0.000
J33.9 Nasal polyp, unspecified	0.690	0.310	0.000
E20-E35 Disorders of other endocrine glands	0.689	0.311	0.000
G20 Parkinson's disease	0.689	0.311	0.000
T86.1 Kidney transplant failure and rejection	0.688	0.312	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.688	0.312	0.000
Y83.0 Surgical operation with transplant of whole organ	0.688	0.312	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.687	0.313	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.687	0.313	0.000
M06 Other rheumatoid arthritis	0.687	0.313	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.686	0.314	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.686	0.314	0.000
M10.99 Gout, unspecified (Site unspecified)	0.685	0.315	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.685	0.315	0.000
V80-V89 Other land transport accidents	0.684	0.315	0.000
O62.2 Other uterine inertia	0.684	0.316	0.000
T93 Sequelae of injuries of lower limb	0.684	0.316	0.000
M25.4 Effusion of joint	0.683	0.317	0.000
O45 Premature separation of placenta [abruptio placentae]	0.683	0.317	0.000
O33 Maternal care for known or suspected disproportion	0.683	0.317	0.000
O31 Complications specific to multiple gestation	0.683	0.317	0.000
O40 Polyhydramnios	0.683	0.317	0.000
S43.1 Dislocation of acromioclavicular joint	0.683	0.317	0.000
O62.0 Primary inadequate contractions	0.681	0.319	0.000
G95 Other diseases of spinal cord	0.681	0.319	0.000
I69 Sequelae of cerebrovascular disease	0.681	0.319	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.680	0.320	0.000
G36 Other acute disseminated demyelination	0.680	0.320	0.000
M13.94 Arthritis, unspecified (Hand)	0.680	0.320	0.000
M83 Adult osteomalacia	0.679	0.321	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.679	0.321	0.000
M33 Dermatopolymyositis	0.679	0.321	0.000
M32 Systemic lupus erythematosus	0.679	0.321	0.000
M30 Polyarteritis nodosa and related conditions	0.679	0.321	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.678	0.322	0.000
M19.8 Other specified arthrosis	0.678	0.322	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.677	0.323	0.000
G70 Myasthenia gravis and other myoneural disorders	0.677	0.323	0.000
V10-V19 Pedal cyclist injured in transport accident	0.676	0.323	0.000
D73 Diseases of spleen	0.676	0.324	0.000
M13.8 Other specified arthritis	0.676	0.324	0.000
M13.1 Monoarthritis, not elsewhere classified	0.676	0.324	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.675	0.325	0.000
M81.98 Osteoporosis, unspecified (Other)	0.675	0.325	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.674	0.326	0.000
S61.8 Open wound of other parts of wrist and hand	0.674	0.326	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.674	0.326	0.000
T79-T79 Certain early complications of trauma	0.673	0.327	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.673	0.327	0.000
G60 Hereditary and idiopathic neuropathy	0.673	0.327	0.000
J85.2 Abscess of lung without pneumonia	0.672	0.328	0.000
D55-D59 Haemolytic anaemias	0.672	0.328	0.000
E78.5 Hyperlipidaemia, unspecified	0.672	0.328	0.000
S48 Traumatic amputation of shoulder and upper arm	0.671	0.329	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.671	0.329	0.000
S44 Injury of nerves at shoulder and upper arm level	0.671	0.329	0.000
S41 Open wound of shoulder and upper arm	0.671	0.329	0.000
S47 Crushing injury of shoulder and upper arm	0.671	0.329	0.000
M22.8 Other disorders of patella	0.671	0.329	0.000
O20.8 Other haemorrhage in early pregnancy	0.671	0.329	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.671	0.329	0.000
O02 Other abnormal products of conception	0.670	0.330	0.000
E40-E46 Malnutrition	0.670	0.330	0.000
J33.8 Other polyp of sinus	0.669	0.331	0.000
M25.0 Haemarthrosis	0.668	0.331	0.000
A04 Other bacterial intestinal infections	0.668	0.332	0.000
W20-W49 Exposure to inanimate mechanical forces	0.668	0.332	0.000
I00-I02 Acute rheumatic fever	0.667	0.332	0.000
M65-M68 Disorders of synovium and tendon	0.667	0.333	0.001
M34.8 Other forms of systemic sclerosis	0.667	0.333	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.666	0.334	0.000
S12 Fracture of neck	0.665	0.335	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.665	0.335	0.000
I60 Subarachnoid haemorrhage	0.664	0.336	0.000
O46.8 Other antepartum haemorrhage	0.664	0.336	0.000
M94 Other disorders of cartilage	0.664	0.336	0.000
F32 Depressive episode	0.664	0.336	0.000
O21.0 Mild hyperemesis gravidarum	0.663	0.337	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.661	0.339	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.661	0.339	0.000
D74 Methaemoglobinaemia	0.661	0.339	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.661	0.339	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.661	0.339	0.000
T90 Sequelae of injuries of head	0.661	0.339	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.660	0.340	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.659	0.341	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.658	0.342	0.000
O36.9 Maternal care for foetal problem, unspecified	0.658	0.342	0.000
T86.0 Bone-marrow transplant rejection	0.658	0.342	0.000
O36.8 Maternal care for other specified foetal problems	0.658	0.342	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.657	0.343	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.657	0.343	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.657	0.343	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.657	0.343	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.657	0.343	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.657	0.343	0.000
T36 Poisoning by systemic antibiotics	0.657	0.343	0.000
S69 Other and unspecified injuries of wrist and hand	0.656	0.344	0.000
S65 Injury of blood vessels at wrist and hand level	0.656	0.344	0.000
S50-S59 Injuries to the elbow and forearm	0.656	0.344	0.000
S40 Superficial injury of shoulder and upper arm	0.656	0.344	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.656	0.344	0.000
J04 Acute laryngitis and tracheitis	0.655	0.345	0.000
O82 Single delivery by Caesarean section	0.654	0.346	0.000
M82.1 Osteoporosis in endocrine disorders	0.654	0.346	0.000
M22.3 Other derangements of patella	0.654	0.346	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.653	0.347	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.653	0.347	0.000
E50-E64 Other nutritional deficiencies	0.652	0.347	0.000
G24.9 Dystonia, unspecified	0.652	0.348	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.652	0.348	0.000
E12 Malnutrition-related diabetes mellitus	0.652	0.348	0.000
J43 Emphysema	0.652	0.348	0.000
O62.3 Precipitate labour	0.650	0.350	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.650	0.350	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.650	0.350	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.650	0.350	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.649	0.350	0.000
Chapter XXII Codes for special purposes	0.649	0.351	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.649	0.351	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.649	0.351	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.648	0.352	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.648	0.352	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.648	0.352	0.000
B99-B99 Other infectious diseases	0.648	0.352	0.000
G62.8 Other specified polyneuropathies	0.648	0.352	0.000
D61 Other aplastic anaemias	0.647	0.353	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.647	0.353	0.000
M22.1 Recurrent subluxation of patella	0.646	0.353	0.000
M22.9 Disorder of patella, unspecified	0.646	0.353	0.000
M22.0 Recurrent dislocation of patella	0.646	0.353	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.646	0.354	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.646	0.354	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.645	0.355	0.000
M11 Other crystal arthropathies	0.644	0.355	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.644	0.356	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.644	0.356	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.644	0.356	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.644	0.356	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.644	0.356	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.644	0.356	0.000
M45-M49 Spondylopathies	0.644	0.356	0.000
A80-A89 Viral infections of the central nervous system	0.644	0.356	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.644	0.356	0.000
D68.5 Primary Thrombophilia	0.643	0.357	0.000
M89 Other disorders of bone	0.643	0.357	0.000
E11.8 With unspecified complications	0.643	0.357	0.000
E11.7 With multiple complications	0.643	0.357	0.000
E11.1 With ketoacidosis	0.643	0.357	0.000
E11.0 With coma	0.643	0.357	0.000
Q80-Q89 Other congenital malformations	0.642	0.358	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.642	0.358	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.641	0.359	0.000
G64 Other disorders of peripheral nervous system	0.640	0.359	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.640	0.360	0.000
O36.4 Maternal care for intra-uterine death	0.640	0.360	0.000
O36.2 Maternal care for hydrops foetalis	0.640	0.360	0.000
O36.1 Maternal care for other isoimmunisation	0.640	0.360	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.639	0.361	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.639	0.361	0.000
B65-B83 Helminthiases	0.639	0.361	0.000
B50-B64 Protozoal diseases	0.639	0.361	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.639	0.361	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.639	0.361	0.000
A75-A79 Rickettsioses	0.639	0.361	0.000
A70-A74 Other diseases caused by chlamydiae	0.639	0.361	0.000
A65-A69 Other spirochaetal diseases	0.639	0.361	0.000
A20-A28 Certain zoonotic bacterial diseases	0.639	0.361	0.000
A15-A19 Tuberculosis	0.639	0.361	0.000
Y04.8 Other specified place	0.639	0.361	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.639	0.361	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.638	0.362	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.638	0.362	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.637	0.362	0.000
M34.9 Systemic sclerosis, unspecified	0.637	0.363	0.000
B35-B49 Mycoses	0.636	0.364	0.000
G72 Other myopathies	0.635	0.365	0.000
O66 Other obstructed labour	0.635	0.365	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.635	0.365	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.633	0.367	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.633	0.367	0.000
G92 Toxic encephalopathy	0.633	0.367	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.631	0.369	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.631	0.369	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.631	0.369	0.000
S43.4 Sprain and strain of shoulder joint	0.631	0.369	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.631	0.369	0.000
S43.2 Dislocation of sternoclavicular joint	0.631	0.369	0.000
M87 Osteonecrosis	0.631	0.369	0.000
E87.0 Hyperosmolality and hypernatraemia	0.631	0.369	0.000
S82 Fracture of lower leg, including ankle	0.630	0.370	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations