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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74908414
log Bayes Factor = 15.1657
Chromosome 6   position 159,622,266  (GRCh37) Explore rs74908414 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.995 0.005 0.000
H25-H28 Disorders of lens
0.994 0.006 0.000
I20 Angina pectoris
0.993 0.007 0.000
H25 Senile cataract
0.992 0.008 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.991 0.009 0.000
H25.8 Other senile cataract
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
I50 Heart failure
0.988 0.012 0.000
Chapter XI Diseases of the digestive system
0.983 0.017 0.000
I50.1 Left ventricular failure
0.980 0.020 0.000
I25.1 Atherosclerotic heart disease
0.975 0.025 0.000
I25.2 Old myocardial infarction
0.973 0.027 0.000
E83 Disorders of mineral metabolism
0.968 0.032 0.000
I10-I15 Hypertensive diseases
0.964 0.036 0.000
K90-K93 Other diseases of the digestive system
0.963 0.037 0.000
E10-E14 Diabetes mellitus
0.950 0.050 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.949 0.051 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.947 0.053 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.945 0.055 0.000
I20.8 Other forms of angina pectoris
0.945 0.055 0.000
I20.0 Unstable angina
0.945 0.055 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.944 0.056 0.000
I60-I69 Cerebrovascular diseases
0.941 0.059 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.939 0.061 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.920 0.080 0.000
E83.1 Disorders of iron metabolism
0.918 0.082 0.000
I42 Cardiomyopathy
0.916 0.084 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.913 0.087 0.000
I10 Essential (primary) hypertension
0.909 0.091 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.908 0.092 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.905 0.095 0.000
I21 Acute myocardial infarction
0.904 0.096 0.000
K65-K67 Diseases of peritoneum
0.902 0.098 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.901 0.099 0.000
W00-W19 Falls
0.892 0.108 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.892 0.108 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.891 0.109 0.000
K91.4 Colostomy and enterostomy malfunction
0.890 0.110 0.000
S90-S99 Injuries to the ankle and foot
0.889 0.111 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.885 0.115 0.000
L03 Cellulitis
0.879 0.121 0.000
I63 Cerebral infarction
0.871 0.129 0.000
K65 Peritonitis
0.870 0.130 0.000
K70-K77 Diseases of liver
0.866 0.134 0.000
E83.4 Disorders of magnesium metabolism
0.862 0.138 0.000
I50.9 Heart failure, unspecified
0.861 0.139 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.852 0.148 0.000
I42.0 Dilated cardiomyopathy
0.852 0.148 0.000
E16 Other disorders of pancreatic internal secretion
0.851 0.149 0.000
I25.5 Ischaemic cardiomyopathy
0.850 0.150 0.000
I24 Other acute ischaemic heart diseases
0.850 0.150 0.000
L03.1 Cellulitis of other parts of limb
0.846 0.154 0.000
E20-E35 Disorders of other endocrine glands
0.843 0.157 0.000
I63.9 Cerebral infarction, unspecified
0.841 0.159 0.000
E87.7 Fluid overload
0.841 0.159 0.000
H25.1 Senile nuclear cataract
0.838 0.162 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.836 0.164 0.000
I34 Nonrheumatic mitral valve disorders
0.836 0.164 0.000
S70-S79 Injuries to the hip and thigh
0.836 0.164 0.000
I20.9 Angina pectoris, unspecified
0.831 0.169 0.000
H43-H45 Disorders of vitreous body and globe
0.828 0.172 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.826 0.174 0.000
I05-I09 Chronic rheumatic heart diseases
0.821 0.179 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.820 0.180 0.000
E14 Unspecified diabetes mellitus
0.820 0.180 0.000
E65-E68 Obesity and other hyperalimentation
0.819 0.181 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.818 0.182 0.000
I45 Other conduction disorders
0.818 0.182 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.813 0.186 0.000
E87.5 Hyperkalaemia
0.810 0.190 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.809 0.191 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.809 0.191 0.000
K50-K52 Noninfective enteritis and colitis
0.808 0.192 0.000
E16.2 Hypoglycaemia, unspecified
0.807 0.193 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.807 0.193 0.000
H04 Disorders of lachrymal system
0.805 0.195 0.000
K65.0 Acute peritonitis
0.804 0.196 0.000
E11 Non-insulin-dependent diabetes mellitus
0.802 0.198 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.802 0.198 0.000
H55-H59 Other disorders of eye and adnexa
0.800 0.200 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.796 0.204 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.795 0.205 0.000
I12 Hypertensive renal disease
0.794 0.206 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.792 0.208 0.000
V20-V29 Motorcycle rider injured in transport accident
0.790 0.210 0.000
K65.9 Peritonitis, unspecified
0.787 0.213 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.785 0.215 0.000
K04 Diseases of pulp and periapical tissues
0.785 0.215 0.000
H53-H54 Visual disturbances and blindness
0.784 0.215 0.000
K55-K64 Other diseases of intestines
0.780 0.220 0.000
I30 Acute pericarditis
0.779 0.221 0.000
S92 Fracture of foot, except ankle
0.777 0.223 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.777 0.223 0.000
E50-E64 Other nutritional deficiencies
0.777 0.223 0.000
K14 Diseases of tongue
0.777 0.223 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.776 0.224 0.000
S91 Open wound of ankle and foot
0.775 0.225 0.000
E10 Insulin-dependent diabetes mellitus
0.773 0.227 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.769 0.231 0.000
I25.3 Aneurysm of heart
0.769 0.231 0.000
Y52 Agents primarily affecting the cardiovascular system
0.768 0.231 0.000
I49 Other cardiac arrhythmias
0.768 0.232 0.000
K90 Intestinal malabsorption
0.765 0.235 0.000
I15 Secondary hypertension
0.764 0.236 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.764 0.236 0.000
K13 Other diseases of lip and oral mucosa
0.764 0.236 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.763 0.237 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.759 0.241 0.000
H25.9 Senile cataract, unspecified
0.754 0.246 0.000
T86 Failure and rejection of transplanted organs and tissues
0.753 0.247 0.000
H04.1 Other disorders of lachrymal gland
0.748 0.252 0.000
S40-S49 Injuries to the shoulder and upper arm
0.747 0.253 0.000
E13 Other specified diabetes mellitus
0.747 0.253 0.000
Y57 Other and unspecified drugs and medicaments
0.745 0.254 0.000
K50 Crohn's disease [regional enteritis]
0.744 0.256 0.000
K70 Alcoholic liver disease
0.742 0.257 0.000
H10-H13 Disorders of conjunctiva
0.742 0.258 0.000
W50-W64 Exposure to animate mechanical forces
0.741 0.258 0.000
I33 Acute and subacute endocarditis
0.741 0.259 0.000
M05-M14 Inflammatory polyarthropathies
0.739 0.261 0.000
H27 Other disorders of lens
0.739 0.261 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.734 0.265 0.000
E88 Other metabolic disorders
0.734 0.266 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.732 0.268 0.000
Y43 Primarily systemic agents
0.731 0.269 0.000
S50-S59 Injuries to the elbow and forearm
0.730 0.270 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.729 0.270 0.000
I22 Subsequent myocardial infarction
0.728 0.272 0.000
K04.8 Radicular cyst
0.728 0.272 0.000
E87.2 Acidosis
0.726 0.274 0.000
S10-S19 Injuries to the neck
0.726 0.274 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.724 0.276 0.000
K74 Fibrosis and cirrhosis of liver
0.723 0.277 0.000
E14.9 Without complications
0.723 0.277 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.721 0.279 0.000
V10-V19 Pedal cyclist injured in transport accident
0.720 0.280 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.720 0.280 0.000
K61 Abscess of anal and rectal regions
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E73 Lactose intolerance
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
L85 Other epidermal thickening
0.714 0.286 0.000
L08 Other local infections of skin and subcutaneous tissue
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.286 0.000
I48 Atrial fibrillation and flutter
0.713 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.286 0.000
I40 Acute myocarditis
0.713 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.286 0.000
I37 Pulmonary valve disorders
0.713 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.286 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.712 0.287 0.000
W06 Fall involving bed
0.712 0.288 0.000
H25.2 Senile cataract, morgagnian type
0.711 0.289 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.711 0.289 0.000
K14.8 Other diseases of tongue
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.290 0.000
Y10-Y34 Event of undetermined intent
0.709 0.290 0.000
Y00-Y09 Assault
0.709 0.290 0.000
X85-X99 Assault
0.709 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.290 0.000
X50-X57 Overexertion, travel and privation
0.709 0.290 0.000
X30-X39 Exposure to forces of nature
0.709 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.290 0.000
X10-X19 Contact with heat and hot substances
0.709 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.290 0.000
W75-W84 Other accidental threats to breathing
0.709 0.290 0.000
W65-W74 Accidental drowning and submersion
0.709 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.290 0.000
V95-V97 Air and space transport accidents
0.709 0.290 0.000
V90-V94 Water transport accidents
0.709 0.290 0.000
V80-V89 Other land transport accidents
0.709 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.290 0.000
I12.0 Hypertensive renal disease with renal failure
0.708 0.292 0.000
M06 Other rheumatoid arthritis
0.705 0.295 0.000
K07 Dentofacial anomalies [including malocclusion]
0.704 0.296 0.000
W19 Unspecified fall
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
E83.5 Disorders of calcium metabolism
0.704 0.296 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.703 0.297 0.000
E40-E46 Malnutrition
0.703 0.297 0.000
L03.0 Cellulitis of finger and toe
0.702 0.298 0.000
Q18 Other congenital malformations of face and neck
0.702 0.298 0.000
I77 Other disorders of arteries and arterioles
0.702 0.298 0.000
L81 Other disorders of pigmentation
0.702 0.298 0.000
K11 Diseases of salivary glands
0.700 0.300 0.000
H01 Other inflammation of eyelid
0.698 0.302 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.696 0.304 0.000
I45.5 Other specified heart block
0.696 0.304 0.000
I21.9 Acute myocardial infarction, unspecified
0.696 0.304 0.000
I42.9 Cardiomyopathy, unspecified
0.695 0.305 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.694 0.306 0.000
E83.8 Other disorders of mineral metabolism
0.694 0.306 0.000
E83.2 Disorders of zinc metabolism
0.694 0.306 0.000
E83.0 Disorders of copper metabolism
0.694 0.306 0.000
H43 Disorders of vitreous body
0.694 0.306 0.000
E78.2 Mixed hyperlipidaemia
0.693 0.307 0.000
I20.1 Angina pectoris with documented spasm
0.692 0.308 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.692 0.308 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.692 0.308 0.000
I11 Hypertensive heart disease
0.692 0.308 0.000
I13 Hypertensive heart and renal disease
0.691 0.308 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.691 0.309 0.000
T87 Complications peculiar to reattachment and amputation
0.691 0.309 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.690 0.310 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.690 0.310 0.000
L03.8 Cellulitis of other sites
0.690 0.310 0.000
E11.2 With renal complications
0.690 0.310 0.000
I35 Nonrheumatic aortic valve disorders
0.688 0.312 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.688 0.312 0.000
Chapter I Certain infectious and parasitic diseases
0.688 0.312 0.000
W13 Fall from, out of or through building or structure
0.687 0.312 0.000
T66-T78 Other and unspecified effects of external causes
0.683 0.317 0.000
S72 Fracture of femur
0.683 0.317 0.000
I34.1 Mitral (valve) prolapse
0.683 0.317 0.000
E12 Malnutrition-related diabetes mellitus
0.681 0.319 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.680 0.320 0.000
K91.5 Postcholecystectomy syndrome
0.680 0.320 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.680 0.320 0.000
K91.1 Postgastric surgery syndromes
0.680 0.320 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.680 0.320 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.679 0.321 0.000
T33-T35 Frostbite
0.679 0.321 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.679 0.321 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.679 0.321 0.000
T00-T07 Injuries involving multiple body regions
0.679 0.321 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.322 0.000
Y58 Bacterial vaccines
0.677 0.322 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.322 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.322 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.677 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.677 0.322 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.322 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.677 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.322 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.322 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.322 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.677 0.322 0.000
L10-L14 Bullous disorders
0.677 0.323 0.000
I38 Endocarditis, valve unspecified
0.676 0.323 0.000
K72 Hepatic failure, not elsewhere classified
0.676 0.324 0.000
E11.5 With peripheral circulatory complications
0.676 0.324 0.000
Y42.7 Androgens and anabolic congeners
0.675 0.325 0.000
K58 Irritable bowel syndrome
0.675 0.325 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.675 0.325 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.675 0.325 0.000
I49.4 Other and unspecified premature depolarisation
0.675 0.325 0.000
X60-X84 Intentional self-harm
0.673 0.326 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.673 0.326 0.000
E87.4 Mixed disorder of acid-base balance
0.673 0.326 0.000
E87.3 Alkalosis
0.673 0.326 0.000
E22 Hyperfunction of pituitary gland
0.673 0.327 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.671 0.329 0.000
E83.3 Disorders of phosphorus metabolism
0.669 0.331 0.000
W10 Fall on and from stairs and steps
0.669 0.331 0.000
E65 Localised adiposity
0.669 0.331 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.669 0.331 0.000
K50.9 Crohn's disease, unspecified
0.668 0.332 0.000
S91.1 Open wound of toe(s) without damage to nail
0.667 0.333 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.667 0.333 0.000
E87.0 Hyperosmolality and hypernatraemia
0.667 0.333 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.666 0.333 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.665 0.335 0.000
K91.3 Postoperative intestinal obstruction
0.664 0.336 0.000
E10.4 With neurological complications
0.664 0.336 0.000
K62 Other diseases of anus and rectum
0.664 0.336 0.000
L85.8 Other specified epidermal thickening
0.664 0.336 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.662 0.338 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.660 0.340 0.000
L04 Acute lymphadenitis
0.659 0.340 0.000
L01 Impetigo
0.659 0.340 0.000
L00 Staphylococcal scalded skin syndrome
0.659 0.340 0.000
S20-S29 Injuries to the thorax
0.659 0.340 0.000
I34.0 Mitral (valve) insufficiency
0.659 0.341 0.000
W18 Other fall on same level
0.658 0.342 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.658 0.342 0.000
I24.8 Other forms of acute ischaemic heart disease
0.657 0.343 0.000
I08 Multiple valve diseases
0.657 0.343 0.000
I42.8 Other cardiomyopathies
0.657 0.343 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.657 0.343 0.000
I42.6 Alcoholic cardiomyopathy
0.657 0.343 0.000
I42.5 Other restrictive cardiomyopathy
0.657 0.343 0.000
I42.4 Endocardial fibroelastosis
0.657 0.343 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.657 0.343 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.657 0.343 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.656 0.344 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.655 0.345 0.000
E15 Nondiabetic hypoglycaemic coma
0.655 0.345 0.000
W20-W49 Exposure to inanimate mechanical forces
0.654 0.346 0.000
S90 Superficial injury of ankle and foot
0.652 0.348 0.000
T86.1 Kidney transplant failure and rejection
0.652 0.348 0.000
L94 Other localised connective tissue disorders
0.651 0.349 0.000
I07 Rheumatic tricuspid valve diseases
0.650 0.350 0.000
W07 Fall involving chair
0.650 0.350 0.000
K61.0 Anal abscess
0.649 0.351 0.000
Y84.1 Kidney dialysis
0.649 0.351 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.649 0.351 0.000
S92.2 Fracture of other tarsal bone(s)
0.649 0.351 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.648 0.352 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.648 0.352 0.000
L40-L45 Papulosquamous disorders
0.648 0.352 0.000
I42.2 Other hypertrophic cardiomyopathy
0.648 0.352 0.000
E78.5 Hyperlipidaemia, unspecified
0.648 0.352 0.000
H18 Other disorders of cornea
0.647 0.353 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.647 0.353 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.646 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.646 0.354 0.000
Q80-Q89 Other congenital malformations
0.646 0.354 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.646 0.354 0.000
Q50-Q56 Congenital malformations of genital organs
0.646 0.354 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.354 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.355 0.000
M80-M85 Disorders of bone density and structure
0.644 0.356 0.000
L89 Decubitus ulcer
0.643 0.357 0.000
I45.3 Trifascicular block
0.642 0.358 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.642 0.358 0.000
D60-D64 Aplastic and other anaemias
0.641 0.359 0.000
M06.9 Rheumatoid arthritis, unspecified
0.641 0.359 0.000
W17 Other fall from one level to another
0.640 0.360 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.640 0.360 0.000
W15 Fall from cliff
0.640 0.360 0.000
W14 Fall from tree
0.640 0.360 0.000
W12 Fall on and from scaffolding
0.640 0.360 0.000
W11 Fall on and from ladder
0.640 0.360 0.000
W09 Fall involving playground equipment
0.640 0.360 0.000
W08 Fall involving other furniture
0.640 0.360 0.000
W05 Fall involving wheelchair
0.640 0.360 0.000
W04 Fall while being carried or supported by other persons
0.640 0.360 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.640 0.360 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.640 0.360 0.000
W00 Fall on same level involving ice and snow
0.640 0.360 0.000
K03 Other diseases of hard tissues of teeth
0.640 0.360 0.000
K00 Disorders of tooth development and eruption
0.640 0.360 0.000
I69 Sequelae of cerebrovascular disease
0.639 0.361 0.000
E78.8 Other disorders of lipoprotein metabolism
0.639 0.361 0.000
E78.6 Lipoprotein deficiency
0.639 0.361 0.000
E78.4 Other hyperlipidaemia
0.639 0.361 0.000
E78.3 Hyperchylomicronaemia
0.639 0.361 0.000
E78.1 Pure hyperglyceridaemia
0.639 0.361 0.000
S73.0 Dislocation of hip
0.639 0.361 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.638 0.362 0.000
K02 Dental caries
0.638 0.362 0.000
S92.0 Fracture of calcaneus
0.638 0.362 0.000
S99 Other and unspecified injuries of ankle and foot
0.637 0.363 0.000
S98 Traumatic amputation of ankle and foot
0.637 0.363 0.000
S97 Crushing injury of ankle and foot
0.637 0.363 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.637 0.363 0.000
S95 Injury of blood vessels at ankle and foot level
0.637 0.363 0.000
S94 Injury of nerves at ankle and foot level
0.637 0.363 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.637 0.363 0.000
I49.9 Cardiac arrhythmia, unspecified
0.637 0.363 0.000
H16 Keratitis
0.637 0.363 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.637 0.363 0.000
Chapter XXI Factors influencing health status and contact with health services
0.635 0.365 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.635 0.365 0.000
H05 Disorders of orbit
0.634 0.366 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.634 0.366 0.000
E10.5 With peripheral circulatory complications
0.634 0.366 0.000
I70 Atherosclerosis
0.633 0.367 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.633 0.367 0.000
E10.1 With ketoacidosis
0.633 0.367 0.000
E28 Ovarian dysfunction
0.632 0.368 0.000
E87.6 Hypokalaemia
0.631 0.369 0.000
H53 Visual disturbances
0.631 0.369 0.000
L81.4 Other melanin hyperpigmentation
0.630 0.370 0.000
E86 Volume depletion
0.629 0.371 0.000
L82 Seborrhoeic keratosis
0.629 0.371 0.000
L83 Acanthosis nigricans
0.627 0.373 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.626 0.374 0.000
K75 Other inflammatory liver diseases
0.626 0.374 0.000
I74 Arterial embolism and thrombosis
0.625 0.375 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.625 0.375 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.625 0.375 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.625 0.375 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.625 0.375 0.000
Y44 Agents primarily affecting blood constituents
0.625 0.375 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.625 0.375 0.000
I30.9 Acute pericarditis, unspecified
0.624 0.375 0.000
D50-D53 Nutritional anaemias
0.624 0.376 0.000
K65.8 Other peritonitis
0.624 0.376 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.623 0.377 0.000
H57 Other disorders of eye and adnexa
0.622 0.378 0.000
H04.2 Epiphora
0.622 0.378 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.621 0.379 0.000
I15.1 Hypertension secondary to other renal disorders
0.621 0.379 0.000
K77 Liver disorders in diseases classified elsewhere
0.621 0.379 0.000
K73 Chronic hepatitis, not elsewhere classified
0.621 0.379 0.000
K71 Toxic liver disease
0.621 0.379 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.620 0.380 0.000
I72 Other aneurysm
0.620 0.380 0.000
Y84.2 Radiological procedure and radiotherapy
0.620 0.380 0.000
I60 Subarachnoid haemorrhage
0.620 0.380 0.000
K10 Other diseases of jaws
0.619 0.381 0.000
E89.3 Postprocedural hypopituitarism
0.619 0.381 0.000
I46 Cardiac arrest
0.619 0.381 0.000
E66 Obesity
0.618 0.382 0.000
H55 Nystagmus and other irregular eye movements
0.617 0.383 0.000
M45-M49 Spondylopathies
0.616 0.384 0.000
K04.6 Periapical abscess with sinus
0.616 0.384 0.000
L50-L54 Urticaria and erythema
0.615 0.385 0.000
K09 Cysts of oral region, not elsewhere classified
0.615 0.385 0.000
Q12 Congenital lens malformations
0.615 0.385 0.000
I67 Other cerebrovascular diseases
0.614 0.386 0.000
K05 Gingivitis and periodontal diseases
0.614 0.386 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.614 0.386 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.613 0.387 0.000
H44 Disorders of globe
0.613 0.387 0.000
E11.1 With ketoacidosis
0.613 0.387 0.000
L20-L30 Dermatitis and eczema
0.613 0.387 0.000
M06.0 Seronegative rheumatoid arthritis
0.612 0.388 0.000
K70.1 Alcoholic hepatitis
0.611 0.389 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.611 0.389 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.610 0.389 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.610 0.389 0.000
E16.4 Abnormal secretion of gastrin
0.610 0.389 0.000
E16.3 Increased secretion of glucagon
0.610 0.389 0.000
E16.1 Other hypoglycaemia
0.610 0.389 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.610 0.389 0.000
H00 Hordeolum and chalazion
0.610 0.389 0.000
I24.1 Dressler's syndrome
0.609 0.390 0.000
E11.6 With other specified complications
0.608 0.392 0.000
L03.2 Cellulitis of face
0.608 0.392 0.000
L05 Pilonidal cyst
0.607 0.393 0.000
S91.3 Open wound of other parts of foot
0.607 0.393 0.000
I47 Paroxysmal tachycardia
0.607 0.393 0.000
W19.4 Street and highway
0.607 0.393 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.606 0.394 0.000
K13.0 Diseases of lips
0.605 0.395 0.000
S70 Superficial injury of hip and thigh
0.605 0.395 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.605 0.395 0.000
E34 Other endocrine disorders
0.605 0.395 0.000
E32 Diseases of thymus
0.605 0.395 0.000
E31 Polyglandular dysfunction
0.605 0.395 0.000
E30 Disorders of puberty, not elsewhere classified
0.605 0.395 0.000
E27 Other disorders of adrenal gland
0.605 0.395 0.000
E26 Hyperaldosteronism
0.605 0.395 0.000
E25 Adrenogenital disorders
0.605 0.395 0.000
E24 Cushing's syndrome
0.605 0.395 0.000
E20 Hypoparathyroidism
0.605 0.395 0.000
M60-M63 Disorders of muscles
0.604 0.396 0.000
E55 Vitamin D deficiency
0.603 0.397 0.000
L03.9 Cellulitis, unspecified
0.603 0.397 0.000
E11.9 Without complications
0.603 0.397 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.603 0.397 0.000
Y57.9 Drug or medicament, unspecified
0.603 0.397 0.000
Chapter VI Diseases of the nervous system
0.602 0.398 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.601 0.399 0.000
E13.9 Without complications
0.601 0.399 0.000
I62 Other nontraumatic intracranial haemorrhage
0.600 0.400 0.000
K74.6 Other and unspecified cirrhosis of liver
0.600 0.400 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.599 0.400 0.000
T86.0 Bone-marrow transplant rejection
0.599 0.401 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.599 0.401 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.599 0.401 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.599 0.401 0.000
S78 Traumatic amputation of hip and thigh
0.599 0.401 0.000
S77 Crushing injury of hip and thigh
0.599 0.401 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.599 0.401 0.000
S75 Injury of blood vessels at hip and thigh level
0.599 0.401 0.000
S74 Injury of nerves at hip and thigh level
0.599 0.401 0.000
S71 Open wound of hip and thigh
0.599 0.401 0.000
M05 Seropositive rheumatoid arthritis
0.598 0.402 0.000
I49.8 Other specified cardiac arrhythmias
0.598 0.402 0.000
I51 Complications and ill-defined descriptions of heart disease
0.598 0.402 0.000
E14.3 With ophthalmic complications
0.597 0.403 0.000
M11 Other crystal arthropathies
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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