TreeWAS – Variant ID: rs74969489

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
I25.1 Atherosclerotic heart disease	0.999	0.001
Chapter XXI Factors influencing health status and contact with health services	0.996	0.004
I25.2 Old myocardial infarction	0.995	0.005
R50-R69 General symptoms and signs	0.993	0.007
Chapter II Neoplasms	0.992	0.008
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.992	0.008
I25.9 Chronic ischaemic heart disease, unspecified	0.990	0.010
I20 Angina pectoris	0.988	0.012
I60-I69 Cerebrovascular diseases	0.986	0.014
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.984	0.016
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.983	0.017
I20.9 Angina pectoris, unspecified	0.981	0.019
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.980	0.020
R60 Oedema, not elsewhere classified	0.974	0.026
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.970	0.030
Chapter XII Diseases of the skin and subcutaneous tissue	0.966	0.034
Z70-Z76 Persons encountering health services in other circumstances	0.965	0.035
I25.8 Other forms of chronic ischaemic heart disease	0.965	0.035
R60.0 Localised oedema	0.957	0.043
I22 Subsequent myocardial infarction	0.954	0.046
Z72 Problems related to lifestyle	0.954	0.046
Z72.0 Tobacco use	0.951	0.049
I84 Haemorrhoids	0.950	0.050
M50-M54 Other dorsopathies	0.949	0.051
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.946	0.054
L00-L08 Infections of the skin and subcutaneous tissue	0.943	0.057
Z95 Presence of cardiac and vascular implants and grafts	0.941	0.059
I67 Other cerebrovascular diseases	0.941	0.059
I64 Stroke, not specified as haemorrhage or infarction	0.936	0.064
Z85 Personal history of malignant neoplasm	0.935	0.065
C78.0 Secondary malignant neoplasm of lung	0.934	0.066
Chapter XI Diseases of the digestive system	0.932	0.068
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.923	0.077
I22.9 Subsequent myocardial infarction of unspecified site	0.922	0.078
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.919	0.081
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.916	0.084
Chapter VI Diseases of the nervous system	0.915	0.085
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.915	0.085
Z85.3 Personal history of malignant neoplasm of breast	0.910	0.090
M54 Dorsalgia	0.910	0.090
I84.1 Internal haemorrhoids with other complications	0.901	0.099
R42 Dizziness and giddiness	0.894	0.106
R52 Pain, not elsewhere classified	0.892	0.108
I21 Acute myocardial infarction	0.892	0.108
M05-M14 Inflammatory polyarthropathies	0.886	0.114
R61 Hyperhidrosis	0.885	0.115
R47-R49 Symptoms and signs involving speech and voice	0.884	0.116
R55 Syncope and collapse	0.883	0.117
R91 Abnormal findings on diagnostic imaging of lung	0.872	0.128
R54 Senility	0.871	0.129
I67.8 Other specified cerebrovascular diseases	0.870	0.130
M20-M25 Other joint disorders	0.868	0.132
Z82.3 Family history of stroke	0.866	0.134
I84.9 Unspecified haemorrhoids without complication	0.865	0.135
R07 Pain in throat and chest	0.864	0.136
G40-G47 Episodic and paroxysmal disorders	0.864	0.136
R93 Abnormal findings on diagnostic imaging of other body structures	0.859	0.141
L03 Cellulitis	0.858	0.142
Z98 Other postsurgical states	0.857	0.143
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.856	0.144
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.850	0.150
D00-D09 In situ neoplasms	0.848	0.152
Z95.5 Presence of coronary angioplasty implant and graft	0.846	0.154
R07.4 Chest pain, unspecified	0.845	0.155
I30-I52 Other forms of heart disease	0.844	0.156
K01 Embedded and impacted teeth	0.842	0.158
Z95.1 Presence of aortocoronary bypass graft	0.839	0.161
I69 Sequelae of cerebrovascular disease	0.834	0.166
M54.3 Sciatica	0.830	0.170
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.827	0.172
G47 Sleep disorders	0.825	0.175
D10-D36 Benign neoplasms	0.821	0.179
M54.5 Low back pain	0.821	0.179
L02 Cutaneous abscess, furuncle and carbuncle	0.820	0.180
M25 Other joint disorders, not elsewhere classified	0.817	0.183
M86-M90 Other osteopathies	0.816	0.184
Z98.8 Other specified postsurgical states	0.816	0.184
Z95.4 Presence of other heart-valve replacement	0.810	0.189
L05 Pilonidal cyst	0.809	0.191
I81 Portal vein thrombosis	0.809	0.191
R61.9 Hyperhidrosis, unspecified	0.808	0.192
R06 Abnormalities of breathing	0.808	0.192
K50-K52 Noninfective enteritis and colitis	0.808	0.192
I24 Other acute ischaemic heart diseases	0.808	0.192
R57 Shock, not elsewhere classified	0.806	0.194
R47 Speech disturbances, not elsewhere classified	0.806	0.194
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.805	0.195
D22 Melanocytic naevi	0.805	0.195
C79 Secondary malignant neoplasm of other sites	0.804	0.196
Z89 Acquired absence of limb	0.801	0.199
R00 Abnormalities of heart beat	0.801	0.199
C50-C50 Malignant neoplasm of breast	0.801	0.199
I80 Phlebitis and thrombophlebitis	0.800	0.200
Chapter XXII Codes for special purposes	0.798	0.202
K14 Diseases of tongue	0.793	0.207
K01.1 Impacted teeth	0.790	0.210
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.789	0.211
G80-G83 Cerebral palsy and other paralytic syndromes	0.789	0.211
I20.8 Other forms of angina pectoris	0.789	0.211
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.789	0.211
R59 Enlarged lymph nodes	0.786	0.214
I87 Other disorders of veins	0.784	0.216
R52.1 Chronic intractable pain	0.784	0.216
I67.2 Cerebral atherosclerosis	0.782	0.218
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.780	0.220
C78.2 Secondary malignant neoplasm of pleura	0.777	0.223
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.777	0.223
M70-M79 Other soft tissue disorders	0.776	0.224
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.776	0.224
R00.1 Bradycardia, unspecified	0.774	0.226
Chapter XX External causes of morbidity and mortality	0.774	0.226
M65-M68 Disorders of synovium and tendon	0.771	0.229
K20-K31 Diseases of oesophagus, stomach and duodenum	0.770	0.230
L03.2 Cellulitis of face	0.769	0.231
Chapter IV Endocrine, nutritional and metabolic diseases	0.769	0.231
Z91 Personal history of risk-factors, not elsewhere classified	0.764	0.236
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.764	0.236
I51 Complications and ill-defined descriptions of heart disease	0.764	0.236
M54.39 Sciatica (Site unspecified)	0.764	0.236
Z85.9 Personal history of malignant neoplasm, unspecified	0.762	0.238
Z95.2 Presence of prosthetic heart valve	0.759	0.241
I21.0 Acute transmural myocardial infarction of anterior wall	0.758	0.242
Z40-Z54 Persons encountering health services for specific procedures and health care	0.756	0.244
R60.9 Oedema, unspecified	0.756	0.244
M05 Seropositive rheumatoid arthritis	0.756	0.244
M54.56 Low back pain (Lumbar region)	0.754	0.246
K02 Dental caries	0.753	0.247
Z86 Personal history of certain other diseases	0.753	0.247
C80 Malignant neoplasm without specification of site	0.750	0.250
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.750	0.250
I21.2 Acute transmural myocardial infarction of other sites	0.749	0.251
Z87 Personal history of other diseases and conditions	0.749	0.251
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.749	0.251
D22.3 Melanocytic naevi of other and unspecified parts of face	0.748	0.252
I49 Other cardiac arrhythmias	0.748	0.252
M50 Cervical disk disorders	0.747	0.253
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.747	0.253
C64-C68 Malignant neoplasms of urinary tract	0.746	0.254
M25.5 Pain in joint	0.743	0.257
K05 Gingivitis and periodontal diseases	0.743	0.257
M00-M03 Infectious arthropathies	0.743	0.257
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.740	0.259
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.740	0.260
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.739	0.261
D03 Melanoma in situ	0.738	0.262
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.738	0.262
I67.9 Cerebrovascular disease, unspecified	0.735	0.265
L50-L54 Urticaria and erythema	0.734	0.265
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.734	0.266
R47.8 Other and unspecified speech disturbances	0.731	0.269
C51-C58 Malignant neoplasms of female genital organs	0.731	0.269
G47.8 Other sleep disorders	0.729	0.271
Z83 Family history of other specific disorders	0.728	0.272
M54.9 Dorsalgia, unspecified	0.727	0.273
K51 Ulcerative colitis	0.727	0.273
L40-L45 Papulosquamous disorders	0.726	0.274
R52.2 Other chronic pain	0.726	0.274
G43 Migraine	0.725	0.275
K14.9 Disease of tongue, unspecified	0.725	0.275
M25.4 Effusion of joint	0.725	0.275
L80-L99 Other disorders of the skin and subcutaneous tissue	0.724	0.276
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.724	0.276
D22.4 Melanocytic naevi of scalp and neck	0.723	0.277
I84.5 External haemorrhoids without complication	0.721	0.279
I86 Varicose veins of other sites	0.721	0.279
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.721	0.279
I84.0 Internal thrombosed haemorrhoids	0.721	0.279
G30-G32 Other degenerative diseases of the nervous system	0.721	0.279
M13 Other arthritis	0.720	0.280
M80-M85 Disorders of bone density and structure	0.719	0.281
I25.5 Ischaemic cardiomyopathy	0.718	0.282
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.3 Aneurysm of heart	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
M53 Other dorsopathies, not elsewhere classified	0.716	0.284
L08 Other local infections of skin and subcutaneous tissue	0.716	0.284
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.714	0.286
Z95.8 Presence of other cardiac and vascular implants and grafts	0.714	0.286
I51.7 Cardiomegaly	0.713	0.287
I84.2 Internal haemorrhoids without complication	0.713	0.287
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.712	0.288
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.712	0.288
R62 Lack of expected normal physiological development	0.712	0.288
R64 Cachexia	0.712	0.288
R58 Haemorrhage, not elsewhere classified	0.712	0.288
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.712	0.288
G47.3 Sleep apnoea	0.711	0.289
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.711	0.289
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.289
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.711	0.289
M91-M94 Chondropathies	0.711	0.289
M60-M63 Disorders of muscles	0.711	0.289
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.710	0.290
I35 Nonrheumatic aortic valve disorders	0.709	0.291
I20.1 Angina pectoris with documented spasm	0.708	0.292
R52.0 Acute pain	0.708	0.292
I68 Cerebrovascular disorders in diseases classified elsewhere	0.707	0.293
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.707	0.293
L05.9 Pilonidal cyst without abscess	0.706	0.294
C76 Malignant neoplasm of other and ill-defined sites	0.705	0.294
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.705	0.295
K35-K38 Diseases of appendix	0.705	0.295
I88 Nonspecific lymphadenitis	0.705	0.295
I82 Other venous embolism and thrombosis	0.705	0.295
D36 Benign neoplasm of other and unspecified sites	0.704	0.296
K30 Dyspepsia	0.703	0.297
Z84 Family history of other conditions	0.703	0.297
Z81 Family history of mental and behavioural disorders	0.703	0.297
D05 Carcinoma in situ of breast	0.703	0.297
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.702	0.298
C83 Diffuse non-Hodgkin's lymphoma	0.702	0.298
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.701	0.298
K07 Dentofacial anomalies [including malocclusion]	0.700	0.300
I69.0 Sequelae of subarachnoid haemorrhage	0.700	0.300
I84.4 External haemorrhoids with other complications	0.699	0.301
R60.1 Generalised oedema	0.698	0.301
Z86.5 Personal history of other mental and behavioural disorders	0.698	0.302
M40-M43 Deforming dorsopathies	0.698	0.302
Z93 Artificial opening status	0.697	0.303
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.697	0.303
C78.4 Secondary malignant neoplasm of small intestine	0.695	0.304
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.695	0.304
C78.1 Secondary malignant neoplasm of mediastinum	0.695	0.304
I60 Subarachnoid haemorrhage	0.694	0.306
Q50-Q56 Congenital malformations of genital organs	0.694	0.306
K26 Duodenal ulcer	0.694	0.306
Z85.6 Personal history of leukaemia	0.694	0.306
L10-L14 Bullous disorders	0.692	0.307
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.692	0.308
Z76 Persons encountering health services in other circumstances	0.692	0.308
Z70 Counselling related to sexual attitude, behaviour and orientation	0.692	0.308
G81 Hemiplegia	0.691	0.309
I05-I09 Chronic rheumatic heart diseases	0.691	0.309
M10 Gout	0.690	0.310
K21 Gastro-oesophageal reflux disease	0.690	0.310
I84.7 Unspecified thrombosed haemorrhoids	0.688	0.312
I85 Oesophageal varices	0.688	0.312
K08 Other disorders of teeth and supporting structures	0.688	0.312
C78.7 Secondary malignant neoplasm of liver	0.687	0.313
L20-L30 Dermatitis and eczema	0.687	0.313
C60-C63 Malignant neoplasms of male genital organs	0.685	0.315
K09 Cysts of oral region, not elsewhere classified	0.685	0.315
I22.8 Subsequent myocardial infarction of other sites	0.684	0.316
I22.1 Subsequent myocardial infarction of inferior wall	0.684	0.316
I22.0 Subsequent myocardial infarction of anterior wall	0.684	0.316
I63 Cerebral infarction	0.684	0.316
Z72.9 Problem related to lifestyle, unspecified	0.684	0.316
Z72.8 Other problems related to lifestyle	0.684	0.316
Z72.6 Gambling and betting	0.684	0.316
Z72.5 High-risk sexual behaviour	0.684	0.316
Z72.4 Inappropriate diet and eating habits	0.684	0.316
Z72.3 Lack of physical exercise	0.684	0.316
Z72.2 Drug use	0.684	0.316
M20 Acquired deformities of fingers and toes	0.683	0.317
L03.3 Cellulitis of trunk	0.683	0.317
M31 Other necrotising vasculopathies	0.683	0.317
D22.7 Melanocytic naevi of lower limb, including hip	0.683	0.317
G70-G73 Diseases of myoneural junction and muscle	0.682	0.318
I84.3 External thrombosed haemorrhoids	0.681	0.319
R07.2 Precordial pain	0.681	0.319
I84.6 Residual haemorrhoidal skin tags	0.681	0.319
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.680	0.320
R90 Abnormal findings on diagnostic imaging of central nervous system	0.678	0.322
R92 Abnormal findings on diagnostic imaging of breast	0.678	0.322
R56 Convulsions, not elsewhere classified	0.677	0.323
I24.9 Acute ischaemic heart disease, unspecified	0.677	0.323
K50 Crohn's disease [regional enteritis]	0.676	0.324
L04 Acute lymphadenitis	0.676	0.324
L01 Impetigo	0.676	0.324
L00 Staphylococcal scalded skin syndrome	0.676	0.324
R06.4 Hyperventilation	0.675	0.325
I67.7 Cerebral arteritis, not elsewhere classified	0.674	0.326
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.674	0.326
I67.5 Moyamoya disease	0.674	0.326
I67.4 Hypertensive encephalopathy	0.674	0.326
I67.3 Progressive vascular leukoencephalopathy	0.674	0.326
I67.0 Dissection of cerebral arteries, nonruptured	0.674	0.326
R68 Other general symptoms and signs	0.674	0.326
Y43 Primarily systemic agents	0.674	0.326
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.674	0.326
Z89.4 Acquired absence of foot and ankle	0.673	0.327
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.673	0.327
I67.1 Cerebral aneurysm, nonruptured	0.673	0.327
R57.2 Septic shock	0.672	0.328
I21.1 Acute transmural myocardial infarction of inferior wall	0.671	0.329
R50 Fever of unknown origin	0.671	0.329
Z87.4 Personal history of diseases of the genito-urinary system	0.671	0.329
Z85.0 Personal history of malignant neoplasm of digestive organs	0.671	0.329
C97 Malignant neoplasms of independent (primary) multiple sites	0.671	0.329
I62 Other nontraumatic intracranial haemorrhage	0.670	0.330
Z97 Presence of other devices	0.669	0.331
Z92 Personal history of medical treatment	0.668	0.332
R45 Symptoms and signs involving emotional state	0.668	0.332
K12 Stomatitis and related lesions	0.668	0.332
D23 Other benign neoplasms of skin	0.668	0.332
Chapter V Mental and behavioural disorders	0.668	0.332
G47.1 Disorders of excessive somnolence [hypersomnias]	0.668	0.332
K10 Other diseases of jaws	0.667	0.333
L85 Other epidermal thickening	0.667	0.333
R47.0 Dysphasia and aphasia	0.666	0.334
K70-K77 Diseases of liver	0.665	0.335
C50 Malignant neoplasm of breast	0.664	0.336
M05.9 Seropositive rheumatoid arthritis, unspecified	0.663	0.337
C92 Myeloid leukaemia	0.662	0.338
R46 Symptoms and signs involving appearance and behaviour	0.662	0.338
R43 Disturbances of smell and taste	0.662	0.338
M11 Other crystal arthropathies	0.661	0.338
R59.9 Enlarged lymph nodes, unspecified	0.661	0.339
M90 Osteopathies in diseases classified elsewhere	0.661	0.339
I33 Acute and subacute endocarditis	0.661	0.339
C77.3 Axillary and upper limb lymph nodes	0.660	0.340
C79.9 Secondary malignant neoplasm, unspecified site	0.659	0.340
Z73 Problems related to life-management difficulty	0.659	0.341
Z43 Attention to artificial openings	0.659	0.341
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.657	0.343
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.657	0.343
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.657	0.343
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.657	0.343
Z82.2 Family history of deafness and hearing loss	0.657	0.343
Z82.1 Family history of blindness and visual loss	0.657	0.343
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.657	0.343
D16 Benign neoplasm of bone and articular cartilage	0.656	0.343
G00-G09 Inflammatory diseases of the central nervous system	0.656	0.344
K03 Other diseases of hard tissues of teeth	0.656	0.344
K00 Disorders of tooth development and eruption	0.656	0.344
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.655	0.345
M54.57 Low back pain (Lumbosacral region)	0.655	0.345
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.655	0.345
I61 Intracerebral haemorrhage	0.655	0.345
K25 Gastric ulcer	0.654	0.346
K06 Other disorders of gingiva and edentulous alveolar ridge	0.654	0.346
R05 Cough	0.653	0.347
M54.8 Other dorsalgia	0.652	0.348
M54.6 Pain in thoracic spine	0.652	0.348
M54.4 Lumbago with sciatica	0.652	0.348
M54.0 Panniculitis affecting regions of neck and back	0.652	0.348
Z54 Convalescence	0.652	0.348
M22 Disorders of patella	0.652	0.348
I49.0 Ventricular fibrillation and flutter	0.652	0.348
D04 Carcinoma in situ of skin	0.650	0.350
R44 Other symptoms and signs involving general sensations and perceptions	0.649	0.350
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.649	0.351
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.649	0.351
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.649	0.351
Chapter XV Pregnancy, childbirth and the puerperium	0.648	0.352
M07 Psoriatic and enteropathic arthropathies	0.648	0.352
C02 Malignant neoplasm of other and unspecified parts of tongue	0.647	0.353
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.647	0.353
R51 Headache	0.646	0.354
R40 Somnolence, stupor and coma	0.644	0.356
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.643	0.357
M34 Systemic sclerosis	0.643	0.357
I87.2 Venous insufficiency (chronic) (peripheral)	0.642	0.358
C79.8 Secondary malignant neoplasm of other specified sites	0.642	0.358
K13 Other diseases of lip and oral mucosa	0.641	0.359
R63 Symptoms and signs concerning food and fluid intake	0.641	0.359
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.641	0.359
D14 Benign neoplasm of middle ear and respiratory system	0.640	0.360
I21.9 Acute myocardial infarction, unspecified	0.640	0.360
E00-E07 Disorders of thyroid gland	0.640	0.360
I21.X Presumed acute myicardial infaction (unconfirmed)	0.639	0.361
I21.3 Acute transmural myocardial infarction of unspecified site	0.639	0.361
K02.9 Dental caries, unspecified	0.637	0.363
D22.1 Melanocytic naevi of eyelid, including canthus	0.637	0.363
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.637	0.363
M86 Osteomyelitis	0.636	0.364
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.636	0.364
M14 Arthropathies in other diseases classified elsewhere	0.635	0.364
M12 Other specific arthropathies	0.635	0.364
M09 Juvenile arthritis in diseases classified elsewhere	0.635	0.364
M08 Juvenile arthritis	0.635	0.364
R06.5 Mouth breathing	0.635	0.365
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.635	0.365
R61.1 Generalised hyperhidrosis	0.635	0.365
R61.0 Localised hyperhidrosis	0.635	0.365
G62 Other polyneuropathies	0.634	0.366
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.634	0.366
Z40 Prophylactic surgery	0.633	0.367
R04 Haemorrhage from respiratory passages	0.633	0.367
M25.46 Effusion of joint (Lower leg)	0.632	0.368
M54.96 Dorsalgia, unspecified (Lumbar region)	0.632	0.368
L03.0 Cellulitis of finger and toe	0.631	0.369
D03.5 Melanoma in situ of trunk	0.631	0.369
D13.1 Stomach	0.630	0.370
M25.9 Joint disorder, unspecified	0.628	0.372
Y40 Systemic antibiotics	0.627	0.373
M54.36 Sciatica (Lumbar region)	0.627	0.373
C85.1 B-cell lymphoma, unspecified	0.627	0.373
L03.9 Cellulitis, unspecified	0.626	0.374
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.625	0.375
L84 Corns and callosities	0.625	0.375
K51.4 Pseudopolyposis of colon	0.625	0.375
R06.8 Other and unspecified abnormalities of breathing	0.624	0.376
K11 Diseases of salivary glands	0.624	0.376
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.624	0.376
M50.2 Other cervical disk displacement	0.623	0.376
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.622	0.377
M33 Dermatopolymyositis	0.622	0.377
M32 Systemic lupus erythematosus	0.622	0.377
M30 Polyarteritis nodosa and related conditions	0.622	0.377
R10 Abdominal and pelvic pain	0.622	0.378
Y43.3 Other antineoplastic drugs	0.622	0.378
M21 Other acquired deformities of limbs	0.622	0.378
G81.9 Hemiplegia, unspecified	0.621	0.379
K05.3 Chronic periodontitis	0.620	0.380
M51 Other intervertebral disk disorders	0.620	0.380
R07.1 Chest pain on breathing	0.619	0.381
Z74 Problems related to care-provider dependency	0.619	0.381
G46 Vascular syndromes of brain in cerebrovascular diseases	0.619	0.381
G41 Status epilepticus	0.619	0.381
Z95.3 Presence of xenogenic heart valve	0.619	0.381
C67 Malignant neoplasm of bladder	0.619	0.381
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.619	0.381
R49 Voice disturbances	0.618	0.382
K51.8 Other ulcerative colitis	0.618	0.382
C81 Hodgkin's disease	0.617	0.383
G47.9 Sleep disorder, unspecified	0.617	0.383
R93.6 Abnormal findings on diagnostic imaging of limbs	0.616	0.384
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.616	0.384
Z94 Transplanted organ and tissue status	0.615	0.385
M25.6 Stiffness of joint, not elsewhere classified	0.615	0.385
M25.50 Pain in joint (Multiple sites)	0.614	0.386
M25.54 Pain in joint (Hand)	0.612	0.388
Q38-Q45 Other congenital malformations of the digestive system	0.612	0.388
Z98.2 Presence of cerebrospinal fluid drainage device	0.612	0.388
Z33 Pregnant state, incidental	0.611	0.388
K40-K46 Hernia	0.611	0.389
Z49 Care involving dialysis	0.611	0.389
I51.8 Other ill-defined heart diseases	0.611	0.389
L03.8 Cellulitis of other sites	0.610	0.390
I35.0 Aortic (valve) stenosis	0.610	0.390
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.610	0.390
C95 Leukaemia of unspecified cell type	0.610	0.390
C94 Other leukaemias of specified cell type	0.610	0.390
C93 Monocytic leukaemia	0.610	0.390
C88 Malignant immunoproliferative diseases	0.610	0.390
C86 Other specified types of T/NK-cell lymphoma	0.610	0.390
C84 Peripheral and cutaneous T-cell lymphomas	0.610	0.390
K04 Diseases of pulp and periapical tissues	0.609	0.391
R06.0 Dyspnoea	0.609	0.391
M25.8 Other specified joint disorders	0.608	0.391
C91 Lymphoid leukaemia	0.608	0.392
K35 Acute appendicitis	0.608	0.392
D02 Carcinoma in situ of middle ear and respiratory system	0.608	0.392
D01 Carcinoma in situ of other and unspecified digestive organs	0.608	0.392
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.608	0.392
M54.1 Radiculopathy	0.608	0.392
M76 Enthesopathies of lower limb, excluding foot	0.607	0.392
Z87.8 Personal history of other specified conditions	0.607	0.393
M72 Fibroblastic disorders	0.607	0.393
M25.57 Pain in joint (Ankle and foot)	0.607	0.393
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.606	0.393
Y52 Agents primarily affecting the cardiovascular system	0.606	0.394
G43.1 Migraine with aura [classical migraine]	0.606	0.394
C77.0 Lymph nodes of head, face and neck	0.605	0.395
I52 Other heart disorders in diseases classified elsewhere	0.605	0.395
I48 Atrial fibrillation and flutter	0.605	0.395
I43 Cardiomyopathy in diseases classified elsewhere	0.605	0.395
I41 Myocarditis in diseases classified elsewhere	0.605	0.395
I40 Acute myocarditis	0.605	0.395
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.605	0.395
I37 Pulmonary valve disorders	0.605	0.395
I36 Nonrheumatic tricuspid valve disorders	0.605	0.395
I32 Pericarditis in diseases classified elsewhere	0.605	0.395
I30 Acute pericarditis	0.605	0.395
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.605	0.395
X50-X57 Overexertion, travel and privation	0.605	0.395
M20.5 Other deformities of toe(s) (acquired)	0.605	0.395
R10.1 Pain localised to upper abdomen	0.604	0.396
M24 Other specific joint derangements	0.604	0.396
K01.0 Embedded teeth	0.604	0.396
Q00-Q07 Congenital malformations of the nervous system	0.603	0.397
I80.8 Phlebitis and thrombophlebitis of other sites	0.603	0.397
K14.0 Glossitis	0.603	0.397
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.603	0.397
E70-E90 Metabolic disorders	0.602	0.398
Z86.7 Personal history of diseases of the circulatory system	0.602	0.398
L03.1 Cellulitis of other parts of limb	0.602	0.398
C77.5 Intrapelvic lymph nodes	0.601	0.399
I34 Nonrheumatic mitral valve disorders	0.601	0.399
M79 Other soft tissue disorders, not elsewhere classified	0.600	0.400
R10.3 Pain localised to other parts of lower abdomen	0.599	0.401
L60-L75 Disorders of skin appendages	0.599	0.401
M54.2 Cervicalgia	0.598	0.402
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.598	0.402
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.598	0.402
I69.1 Sequelae of intracerebral haemorrhage	0.598	0.402
I44 Atrioventricular and left bundle-branch block	0.597	0.403
L05.0 Pilonidal cyst with abscess	0.596	0.404
M67 Other disorders of synovium and tendon	0.595	0.405

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations