TreeWAS – Variant ID: rs75222804

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.997	0.003
M20-M25 Other joint disorders	0.995	0.005
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.994	0.006
M20 Acquired deformities of fingers and toes	0.987	0.013
T93 Sequelae of injuries of lower limb	0.985	0.015
M20.1 Hallux valgus (acquired)	0.980	0.020
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.980	0.020
S80-S89 Injuries to the knee and lower leg	0.977	0.023
Chapter VIII Diseases of the ear and mastoid process	0.972	0.028
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.969	0.031
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.967	0.033
T93.8 Sequelae of other specified injuries of lower limb	0.961	0.039
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.959	0.041
S00-S09 Injuries to the head	0.955	0.045
D50-D53 Nutritional anaemias	0.953	0.047
M65-M68 Disorders of synovium and tendon	0.950	0.050
M24 Other specific joint derangements	0.947	0.053
H65-H75 Diseases of middle ear and mastoid	0.938	0.062
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.937	0.063
D50 Iron deficiency anaemia	0.936	0.064
M05-M14 Inflammatory polyarthropathies	0.930	0.070
Chapter X Diseases of the respiratory system	0.928	0.072
T93.2 Sequelae of other fractures of lower limb	0.927	0.073
S50-S59 Injuries to the elbow and forearm	0.925	0.075
X60-X84 Intentional self-harm	0.923	0.076
D50.9 Iron deficiency anaemia, unspecified	0.918	0.082
H71 Cholesteatoma of middle ear	0.916	0.084
M20.2 Hallux rigidus	0.909	0.091
S82 Fracture of lower leg, including ankle	0.899	0.101
M06 Other rheumatoid arthritis	0.891	0.109
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.888	0.112
J30-J39 Other diseases of upper respiratory tract	0.886	0.114
J40-J47 Chronic lower respiratory diseases	0.883	0.117
Q80-Q89 Other congenital malformations	0.878	0.122
M20.5 Other deformities of toe(s) (acquired)	0.875	0.125
S10-S19 Injuries to the neck	0.873	0.127
J33 Nasal polyp	0.870	0.130
S40-S49 Injuries to the shoulder and upper arm	0.866	0.134
T36-T50 Poisoning by drugs, medicaments and biological substances	0.865	0.135
S81 Open wound of lower leg	0.859	0.141
S09 Other and unspecified injuries of head	0.858	0.142
J33.0 Polyp of nasal cavity	0.856	0.144
M67 Other disorders of synovium and tendon	0.856	0.144
T98 Sequelae of other and unspecified effects of external causes	0.855	0.145
S60-S69 Injuries to the wrist and hand	0.853	0.147
M06.9 Rheumatoid arthritis, unspecified	0.852	0.148
M65 Synovitis and tenosynovitis	0.850	0.150
M24.1 Other articular cartilage disorders	0.850	0.150
T92 Sequelae of injuries of upper limb	0.849	0.151
S80 Superficial injury of lower leg	0.847	0.153
M80-M85 Disorders of bone density and structure	0.847	0.153
M60-M63 Disorders of muscles	0.846	0.154
H90-H95 Other disorders of ear	0.841	0.159
Chapter XXII Codes for special purposes	0.840	0.160
Y40 Systemic antibiotics	0.837	0.163
S00 Superficial injury of head	0.836	0.164
S82.6 Fracture of lateral malleolus	0.832	0.168
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.831	0.169
M13 Other arthritis	0.829	0.171
S90-S99 Injuries to the ankle and foot	0.829	0.171
J00-J06 Acute upper respiratory infections	0.828	0.172
V20-V29 Motorcycle rider injured in transport accident	0.825	0.175
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.823	0.177
J47 Bronchiectasis	0.822	0.178
Q20-Q28 Congenital malformations of the circulatory system	0.821	0.179
M45-M49 Spondylopathies	0.819	0.181
M22 Disorders of patella	0.814	0.186
J36 Peritonsillar abscess	0.810	0.190
H73 Other disorders of tympanic membrane	0.810	0.190
D51 Vitamin B12 deficiency anaemia	0.809	0.191
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.808	0.192
J42 Unspecified chronic bronchitis	0.807	0.193
Y53 Agents primarily affecting the gastro-intestinal system	0.804	0.196
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.802	0.198
D55-D59 Haemolytic anaemias	0.802	0.198
Q50-Q56 Congenital malformations of genital organs	0.801	0.199
S00.1 Contusion of eyelid and periocular area	0.800	0.200
M96.8 Other postprocedural musculoskeletal disorders	0.799	0.201
D50.8 Other iron deficiency anaemias	0.798	0.202
M24.16 Other articular cartilage disorders (Lower leg)	0.798	0.202
M96.0 Pseudarthrosis after fusion or arthrodesis	0.797	0.203
S54 Injury of nerves at forearm level	0.796	0.203
S82.4 Fracture of fibula alone	0.795	0.205
M95.0 Acquired deformity of nose	0.794	0.206
Y47 Sedatives, hypnotics and antianxiety drugs	0.789	0.210
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.788	0.212
V80-V89 Other land transport accidents	0.786	0.214
S82.60 Fracture of lateral malleolus (closed)	0.784	0.216
W00-W19 Falls	0.783	0.217
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.782	0.218
W20-W49 Exposure to inanimate mechanical forces	0.778	0.222
J00 Acute nasopharyngitis [common cold]	0.778	0.222
W50-W64 Exposure to animate mechanical forces	0.777	0.223
V10-V19 Pedal cyclist injured in transport accident	0.773	0.227
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.773	0.227
M67.2 Synovial hypertrophy, not elsewhere classified	0.773	0.227
Y48 Anaesthetics and therapeutic gases	0.771	0.229
M13.9 Arthritis, unspecified	0.770	0.230
J33.8 Other polyp of sinus	0.770	0.230
M91-M94 Chondropathies	0.770	0.230
Q38-Q45 Other congenital malformations of the digestive system	0.767	0.233
M24.2 Disorder of ligament	0.765	0.235
S80.9 Superficial injury of lower leg, unspecified	0.765	0.235
T93.9 Sequelae of unspecified injury of lower limb	0.764	0.236
W75-W84 Other accidental threats to breathing	0.764	0.236
J35 Chronic diseases of tonsils and adenoids	0.761	0.239
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.760	0.240
S05 Injury of eye and orbit	0.759	0.241
Q00-Q07 Congenital malformations of the nervous system	0.758	0.242
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.758	0.242
S06 Intracranial injury	0.757	0.243
Q21 Congenital malformations of cardiac septa	0.755	0.245
S52 Fracture of forearm	0.754	0.246
M21 Other acquired deformities of limbs	0.754	0.246
S02 Fracture of skull and facial bones	0.753	0.247
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.752	0.248
Y00-Y09 Assault	0.751	0.249
H80-H83 Diseases of inner ear	0.750	0.250
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.749	0.250
T20-T25 Burns and corrosions of external body surface, specified by site	0.747	0.253
S46 Injury of muscle and tendon at shoulder and upper arm level	0.746	0.254
H90 Conductive and sensorineural hearing loss	0.745	0.255
S09.8 Other specified injuries of head	0.745	0.255
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.744	0.256
H66 Suppurative and unspecified otitis media	0.743	0.257
V40-V49 Car occupant injured in transport accident	0.742	0.257
S56 Injury of muscle and tendon at forearm level	0.741	0.259
S62 Fracture at wrist and hand level	0.740	0.260
W19 Unspecified fall	0.739	0.261
M24.8 Other specific joint derangements, not elsewhere classified	0.739	0.261
Y57 Other and unspecified drugs and medicaments	0.734	0.266
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.734	0.266
M13.94 Arthritis, unspecified (Hand)	0.734	0.266
X50-X57 Overexertion, travel and privation	0.733	0.267
M13.90 Arthritis, unspecified (Multiple sites)	0.733	0.267
Y44 Agents primarily affecting blood constituents	0.733	0.267
M06.0 Seronegative rheumatoid arthritis	0.731	0.269
M30 Polyarteritis nodosa and related conditions	0.730	0.270
M34 Systemic sclerosis	0.730	0.270
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.730	0.270
S10 Superficial injury of neck	0.729	0.271
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.729	0.271
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.729	0.271
Q85 Phakomatoses, not elsewhere classified	0.727	0.273
M24.5 Contracture of joint	0.726	0.274
T93.0 Sequelae of open wound of lower limb	0.725	0.275
M00-M03 Infectious arthropathies	0.724	0.276
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.723	0.277
M24.4 Recurrent dislocation and subluxation of joint	0.722	0.278
S82.2 Fracture of shaft of tibia	0.722	0.278
S64 Injury of nerves at wrist and hand level	0.722	0.278
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.721	0.279
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.721	0.279
S82.40 Fracture of fibula alone (closed)	0.720	0.280
Y51 Drugs primarily affecting the autonomic nervous system	0.719	0.281
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.717	0.283
S14 Injury of nerves and spinal cord at neck level	0.717	0.283
X20-X29 Contact with venomous animals and plants	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.715	0.285
Y10-Y34 Event of undetermined intent	0.715	0.285
X85-X99 Assault	0.715	0.285
X30-X39 Exposure to forces of nature	0.715	0.285
X10-X19 Contact with heat and hot substances	0.715	0.285
X00-X09 Exposure to smoke, fire and flames	0.715	0.285
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285
W65-W74 Accidental drowning and submersion	0.715	0.285
V98-V99 Other and unspecified transport accidents	0.715	0.285
V95-V97 Air and space transport accidents	0.715	0.285
V90-V94 Water transport accidents	0.715	0.285
V70-V79 Bus occupant injured in transport accident	0.715	0.285
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285
V01-V09 Pedestrian injured in transport accident	0.715	0.285
S89 Other and unspecified injuries of lower leg	0.714	0.286
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.713	0.286
M33 Dermatopolymyositis	0.713	0.286
M32 Systemic lupus erythematosus	0.713	0.286
T95 Sequelae of burns, corrosions and frostbite	0.713	0.287
T94 Sequelae of injuries involving multiple and unspecified body regions	0.713	0.287
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.713	0.287
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.713	0.287
W19.9 Unspecified place	0.712	0.288
T15-T19 Effects of foreign body entering through natural orifice	0.712	0.288
S80.8 Other superficial injuries of lower leg	0.711	0.289
M95.4 Acquired deformity of chest and rib	0.710	0.289
S42 Fracture of shoulder and upper arm	0.708	0.292
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.708	0.292
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.706	0.294
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.706	0.294
T93.4 Sequelae of injury of nerve of lower limb	0.706	0.294
Y40.9 Systemic antibiotic, unspecified	0.706	0.294
M65.8 Other synovitis and tenosynovitis	0.706	0.294
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.706	0.294
X58-X59 Accidental exposure to other and unspecified factors	0.705	0.294
Chapter V Mental and behavioural disorders	0.705	0.295
S61 Open wound of wrist and hand	0.705	0.295
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.704	0.296
M65.9 Synovitis and tenosynovitis, unspecified	0.704	0.296
M99 Biomechanical lesions, not elsewhere classified	0.702	0.297
M15-M19 Arthrosis	0.702	0.298
T79-T79 Certain early complications of trauma	0.702	0.298
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.701	0.298
Q82 Other congenital malformations of skin	0.701	0.299
H83 Other diseases of inner ear	0.701	0.299
S91 Open wound of ankle and foot	0.700	0.300
S88 Traumatic amputation of lower leg	0.700	0.300
S87 Crushing injury of lower leg	0.700	0.300
S85 Injury of blood vessels at lower leg level	0.700	0.300
S84 Injury of nerves at lower leg level	0.700	0.300
S00.0 Superficial injury of scalp	0.699	0.301
Y40.3 Macrolides	0.697	0.303
S81.0 Open wound of knee	0.697	0.303
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.697	0.303
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.695	0.305
Q35-Q37 Cleft lip and cleft palate	0.695	0.305
Q30-Q34 Congenital malformations of the respiratory system	0.695	0.305
J39 Other diseases of upper respiratory tract	0.695	0.305
T92.9 Sequelae of unspecified injury of upper limb	0.694	0.306
H93 Other disorders of ear, not elsewhere classified	0.694	0.306
S51 Open wound of forearm	0.693	0.307
Y53.1 Other antacids and anti-gastric-secretion drugs	0.692	0.308
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.692	0.308
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.691	0.309
X40-X49 Accidental poisoning by and exposure to noxious substances	0.690	0.309
X62.9 Unspecified place	0.690	0.310
M24.0 Loose body in joint	0.689	0.310
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.689	0.311
Y59 Other and unspecified vaccines and biological substances	0.688	0.312
Y58 Bacterial vaccines	0.688	0.312
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.688	0.312
Y50 Central nervous system stimulants, not elsewhere classified	0.688	0.312
Y49 Psychotropic drugs, not elsewhere classified	0.688	0.312
Y46 Antiepileptics and anti-Parkinsonism drugs	0.688	0.312
W29 Contact with other powered hand tools and household machinery	0.686	0.314
Y60-Y69 Misadventures to patients during surgical and medical care	0.686	0.314
S81.7 Multiple open wounds of lower leg	0.685	0.315
M60 Myositis	0.685	0.315
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.685	0.315
S08 Traumatic amputation of part of head	0.684	0.315
S07 Crushing injury of head	0.684	0.315
S04 Injury of cranial nerves	0.684	0.315
S03 Dislocation, sprain and strain of joints and ligaments of head	0.684	0.315
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.684	0.316
D53 Other nutritional anaemias	0.684	0.316
M22.8 Other disorders of patella	0.684	0.316
M62 Other disorders of muscle	0.682	0.317
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.681	0.319
T92.1 Sequelae of fracture of arm	0.680	0.320
M67.0 Short Achilles tendon (acquired)	0.680	0.320
M24.9 Joint derangement, unspecified	0.679	0.321
M24.7 Protrusio acetabuli	0.679	0.321
M24.6 Ankylosis of joint	0.679	0.321
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.679	0.321
M66 Spontaneous rupture of synovium and tendon	0.679	0.321
S09.0 Injury of blood vessels of head, not elsewhere classified	0.678	0.322
S81.8 Open wound of other parts of lower leg	0.678	0.322
S86 Injury of muscle and tendon at lower leg level	0.677	0.322
S30 Superficial injury of abdomen, lower back and pelvis	0.677	0.323
D60-D64 Aplastic and other anaemias	0.677	0.323
H73.9 Disorder of tympanic membrane, unspecified	0.677	0.323
J46 Status asthmaticus	0.675	0.324
M40-M43 Deforming dorsopathies	0.675	0.325
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.675	0.325
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.674	0.326
M84 Disorders of continuity of bone	0.674	0.326
M80 Osteoporosis with pathological fracture	0.674	0.326
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.673	0.327
H68 Eustachian salpingitis and obstruction	0.673	0.327
H67 Otitis media in diseases classified elsewhere	0.673	0.327
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.671	0.328
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.671	0.328
M96.5 Postradiation scoliosis	0.671	0.328
M96.4 Postsurgical lordosis	0.671	0.328
M96.3 Postlaminectomy kyphosis	0.671	0.328
M96.2 Postradiation kyphosis	0.671	0.328
D50.1 Sideropenic dysphagia	0.671	0.329
S19 Other and unspecified injuries of neck	0.670	0.330
Y41 Other systemic anti-infectives and antiparasitics	0.670	0.330
D80-D89 Certain disorders involving the immune mechanism	0.670	0.330
J35.8 Other chronic diseases of tonsils and adenoids	0.669	0.331
H70 Mastoiditis and related conditions	0.669	0.331
Y47.1 Benzodiazepines	0.668	0.332
M11 Other crystal arthropathies	0.668	0.332
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.668	0.332
M85 Other disorders of bone density and structure	0.668	0.332
S54.0 Injury of ulnar nerve at forearm level	0.667	0.333
S02.2 Fracture of nasal bones	0.667	0.333
M14 Arthropathies in other diseases classified elsewhere	0.667	0.333
M12 Other specific arthropathies	0.667	0.333
M09 Juvenile arthritis in diseases classified elsewhere	0.667	0.333
M08 Juvenile arthritis	0.667	0.333
D52 Folate deficiency anaemia	0.666	0.333
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.666	0.334
H83.0 Labyrinthitis	0.666	0.334
T92.0 Sequelae of open wound of upper limb	0.666	0.334
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.665	0.335
S96 Injury of muscle and tendon at ankle and foot level	0.665	0.335
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.665	0.335
T93.1 Sequelae of fracture of femur	0.664	0.336
S59 Other and unspecified injuries of forearm	0.663	0.337
S58 Traumatic amputation of forearm	0.663	0.337
S57 Crushing injury of forearm	0.663	0.337
S55 Injury of blood vessels at forearm level	0.663	0.337
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.663	0.337
Q54 Hypospadias	0.663	0.337
M20.3 Other deformity of hallux (acquired)	0.662	0.337
T98.1 Sequelae of other and unspecified effects of external causes	0.662	0.338
X84 Intentional self-harm by unspecified means	0.662	0.338
X83 Intentional self-harm by other specified means	0.662	0.338
X82 Intentional self-harm by crashing of motor vehicle	0.662	0.338
X81 Intentional self-harm by jumping or lying before moving object	0.662	0.338
X80 Intentional self-harm by jumping from a high place	0.662	0.338
X79 Intentional self-harm by blunt object	0.662	0.338
X77 Intentional self-harm by steam, hot vapours and hot objects	0.662	0.338
X76 Intentional self-harm by smoke, fire and flames	0.662	0.338
X75 Intentional self-harm by explosive material	0.662	0.338
X74 Intentional self-harm by other and unspecified firearm discharge	0.662	0.338
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.662	0.338
X72 Intentional self-harm by handgun discharge	0.662	0.338
X71 Intentional self-harm by drowning and submersion	0.662	0.338
X70 Intentional self-harm by hanging, strangulation and suffocation	0.662	0.338
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.662	0.338
X68 Intentional self-poisoning by and exposure to pesticides	0.662	0.338
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.662	0.338
X65 Intentional self-poisoning by and exposure to alcohol	0.662	0.338
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.662	0.338
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.662	0.338
Q21.0 Ventricular septal defect	0.662	0.338
S52.5 Fracture of lower end of radius	0.659	0.341
M82 Osteoporosis in diseases classified elsewhere	0.657	0.342
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.657	0.343
S50 Superficial injury of forearm	0.656	0.344
S09.9 Unspecified injury of head	0.656	0.344
H90.5 Sensorineural hearing loss, unspecified	0.656	0.344
M22.2 Patellofemoral disorders	0.654	0.346
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.654	0.346
S31 Open wound of abdomen, lower back and pelvis	0.654	0.346
S00.4 Superficial injury of ear	0.653	0.347
S70-S79 Injuries to the hip and thigh	0.653	0.347
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.652	0.348
H73.8 Other specified disorders of tympanic membrane	0.651	0.349
M67.8 Other specified disorders of synovium and tendon	0.651	0.349
M24.13 Other articular cartilage disorders (Forearm)	0.650	0.350
Q21.1 Atrial septal defect	0.648	0.352
M31 Other necrotising vasculopathies	0.647	0.353
S00.7 Multiple superficial injuries of head	0.646	0.354
S62.6 Fracture of other finger	0.646	0.354
S62.3 Fracture of other metacarpal bone	0.645	0.355
M45 Ankylosing spondylitis	0.645	0.355
S82.9 Fracture of lower leg, part unspecified	0.645	0.355
S82.7 Multiple fractures of lower leg	0.645	0.355
V11 Pedal cyclist injured in collision with other pedal cycle	0.642	0.358
D58 Other hereditary haemolytic anaemias	0.642	0.358
H65 Nonsuppurative otitis media	0.642	0.358
M65.4 Radial styloid tenosynovitis [de Quervain]	0.641	0.359
M13.96 Arthritis, unspecified (Lower leg)	0.641	0.359
X67.9 Unspecified place	0.640	0.360
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.639	0.361
F40-F48 Neurotic, stress-related and somatoform disorders	0.639	0.361
M06.8 Other specified rheumatoid arthritis	0.639	0.361
M06.3 Rheumatoid nodule	0.639	0.361
M06.2 Rheumatoid bursitis	0.639	0.361
M06.1 Adult-onset Still's disease	0.639	0.361
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.638	0.362
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.636	0.364
M95.8 Other specified acquired deformities of musculoskeletal system	0.636	0.364
M95.5 Acquired deformity of pelvis	0.636	0.364
M95.3 Acquired deformity of neck	0.636	0.364
M95.2 Other acquired deformity of head	0.636	0.364
M95.1 Cauliflower ear	0.636	0.364
T90 Sequelae of injuries of head	0.636	0.364
Y48.3 Local anaesthetics	0.636	0.364
S54.1 Injury of median nerve at forearm level	0.636	0.364
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.635	0.364
J37 Chronic laryngitis and laryngotracheitis	0.634	0.365
D59 Acquired haemolytic anaemia	0.633	0.367
J41 Simple and mucopurulent chronic bronchitis	0.633	0.367
Q28 Other congenital malformations of circulatory system	0.633	0.367
M47 Spondylosis	0.632	0.368
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.629	0.370
Q84 Other congenital malformations of integument	0.629	0.370
Q83 Congenital malformations of breast	0.629	0.370
Q81 Epidermolysis bullosa	0.629	0.370
Q80 Congenital ichthyosis	0.629	0.370
Y57.8 Other drugs and medicaments	0.629	0.371
S41 Open wound of shoulder and upper arm	0.628	0.372
D62 Acute posthaemorrhagic anaemia	0.627	0.373
S17 Crushing injury of neck	0.626	0.374
S15 Injury of blood vessels at neck level	0.626	0.374
S11 Open wound of neck	0.626	0.374
S18 Traumatic amputation at neck level	0.626	0.374
S16 Injury of muscle and tendon at neck level	0.626	0.374
S10.9 Superficial injury of neck, part unspecified	0.626	0.374
J09-J18 Influenza and pneumonia	0.626	0.374
S91.1 Open wound of toe(s) without damage to nail	0.626	0.374
Q89 Other congenital malformations, not elsewhere classified	0.624	0.376
S00.9 Superficial injury of head, part unspecified	0.624	0.376
J33.1 Polypoid sinus degeneration	0.624	0.376
S69 Other and unspecified injuries of wrist and hand	0.624	0.376
M65.3 Trigger finger	0.624	0.376
M86-M90 Other osteopathies	0.623	0.376
M46 Other inflammatory spondylopathies	0.623	0.377
M20.0 Deformity of finger(s)	0.622	0.378
Q87.4 Marfan's syndrome	0.622	0.378
J04 Acute laryngitis and tracheitis	0.622	0.378
S82.5 Fracture of medial malleolus	0.622	0.378
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.621	0.378
H66.3 Other chronic suppurative otitis media	0.621	0.379
S81.9 Open wound of lower leg, part unspecified	0.621	0.379
S46.0 Injury of tendon of the rotator cuff of shoulder	0.621	0.379
S82.21 Fracture of shaft of tibia (open)	0.621	0.379
S48 Traumatic amputation of shoulder and upper arm	0.621	0.379
S45 Injury of blood vessels at shoulder and upper arm level	0.621	0.379
S44 Injury of nerves at shoulder and upper arm level	0.621	0.379
S47 Crushing injury of shoulder and upper arm	0.621	0.379
W29.9 Unspecified place	0.621	0.379
X78 Intentional self-harm by sharp object	0.620	0.379
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.620	0.380
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.620	0.380
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.620	0.380
T41 Poisoning by anaesthetics and therapeutic gases	0.620	0.380
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.620	0.380
T36 Poisoning by systemic antibiotics	0.620	0.380
Q85.0 Neurofibromatosis (nonmalignant)	0.619	0.381
S82.3 Fracture of lower end of tibia	0.619	0.381
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.618	0.382
S02.8 Fractures of other skull and facial bones	0.618	0.382
J45 Asthma	0.617	0.383
M92 Other juvenile osteochondrosis	0.617	0.383
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.617	0.383
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.615	0.385
S09.7 Multiple injuries of head	0.615	0.385
S09.2 Traumatic rupture of ear drum	0.615	0.385
S09.1 Injury of muscle and tendon of head	0.615	0.385
X60.2 School, other institution and public administrative area	0.615	0.385
J43 Emphysema	0.614	0.386
S46.3 Injury of muscle and tendon of triceps	0.614	0.386
M67.9 Disorder of synovium and tendon, unspecified	0.614	0.386
M67.4 Ganglion	0.614	0.386
M67.3 Transient synovitis	0.614	0.386
V23.4 Driver injured in traffic accident	0.613	0.387
T98.2 Sequelae of certain early complications of trauma	0.613	0.387
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.613	0.387
U88 Agent resistant to multiple antibiotics	0.613	0.387
Q51 Congenital malformations of uterus and cervix	0.612	0.388
S65 Injury of blood vessels at wrist and hand level	0.612	0.388
Y45.5 4-Aminophenol derivatives	0.612	0.388
J06 Acute upper respiratory infections of multiple and unspecified sites	0.612	0.388
M06.98 Rheumatoid arthritis, unspecified (Other)	0.611	0.389
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.611	0.389
M06.4 Inflammatory polyarthropathy	0.610	0.390
M65.2 Calcific tendinitis	0.610	0.390
M65.1 Other infective (teno)synovitis	0.610	0.390
M65.0 Abscess of tendon sheath	0.610	0.390
M24.19 Other articular cartilage disorders (Site unspecified)	0.609	0.391
M24.18 Other articular cartilage disorders (Other)	0.609	0.391
M24.17 Other articular cartilage disorders (Ankle and foot)	0.609	0.391
M24.14 Other articular cartilage disorders (Hand)	0.609	0.391
M24.12 Other articular cartilage disorders (Upper arm)	0.609	0.391
M24.10 Other articular cartilage disorders (Multiple sites)	0.609	0.391
T92.8 Sequelae of other specified injuries of upper limb	0.609	0.391
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.609	0.391
T92.4 Sequelae of injury of nerve of upper limb	0.609	0.391
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.609	0.391
M18 Arthrosis of first carpometacarpal joint	0.609	0.391
T91 Sequelae of injuries of neck and trunk	0.608	0.392
S80.7 Multiple superficial injuries of lower leg	0.607	0.392
M83 Adult osteomalacia	0.607	0.393
Y43 Primarily systemic agents	0.607	0.393
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.607	0.393
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.607	0.393
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.607	0.393
M63 Disorders of muscle in diseases classified elsewhere	0.607	0.393
M61 Calcification and ossification of muscle	0.607	0.393
S61.8 Open wound of other parts of wrist and hand	0.607	0.393
S82.1 Fracture of upper end of tibia	0.607	0.393
S02.20 Fracture of nasal bones (closed)	0.606	0.394
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.605	0.394
S64.4 Injury of digital nerve of other finger	0.605	0.395
Y88 Sequelae of surgical and medical care as external cause	0.605	0.395
S14.3 Injury of brachial plexus	0.604	0.396
J60-J70 Lung diseases due to external agents	0.603	0.397
H94 Other disorders of ear in diseases classified elsewhere	0.603	0.397
S40 Superficial injury of shoulder and upper arm	0.601	0.398
T46 Poisoning by agents primarily affecting the cardiovascular system	0.600	0.399
M24.26 Disorder of ligament (Lower leg)	0.600	0.399
H72 Perforation of tympanic membrane	0.600	0.400
Y40.7 Antifungal antibiotics, systemically used	0.600	0.400
Y40.6 Rifamycins	0.600	0.400
Y40.5 Aminoglycosides	0.600	0.400
Y40.4 Tetracyclines	0.600	0.400
Y40.2 Chloramphenicol group	0.600	0.400

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations