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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7536740
log Bayes Factor = 11.7453
Chromosome 1   position 168,472,921  (GRCh37) Explore rs7536740 on Ensembl!
Variant rs7536740 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
M45-M49 Spondylopathies
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
S90-S99 Injuries to the ankle and foot
0.988 0.012 0.000
S60-S69 Injuries to the wrist and hand
0.983 0.017 0.000
S70-S79 Injuries to the hip and thigh
0.983 0.017 0.000
M05-M14 Inflammatory polyarthropathies
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.977 0.023 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.974 0.026 0.000
Chapter V Mental and behavioural disorders
0.973 0.027 0.000
M47 Spondylosis
0.973 0.027 0.000
Chapter VI Diseases of the nervous system
0.970 0.030 0.000
M06 Other rheumatoid arthritis
0.968 0.032 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.967 0.033 0.000
B95-B98 Bacterial, viral and other infectious agents
0.967 0.033 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.966 0.034 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.964 0.036 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.964 0.036 0.000
S72 Fracture of femur
0.963 0.037 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.962 0.038 0.000
S62 Fracture at wrist and hand level
0.955 0.045 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.954 0.046 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.953 0.047 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.951 0.049 0.000
M06.9 Rheumatoid arthritis, unspecified
0.949 0.051 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.945 0.055 0.000
A30-A49 Other bacterial diseases
0.943 0.057 0.000
M48 Other spondylopathies
0.942 0.058 0.000
M86-M90 Other osteopathies
0.942 0.058 0.000
M50-M54 Other dorsopathies
0.940 0.060 0.000
S72.0 Fracture of neck of femur
0.938 0.062 0.000
L50-L54 Urticaria and erythema
0.932 0.068 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.930 0.070 0.000
Chapter X Diseases of the respiratory system
0.929 0.071 0.000
T86 Failure and rejection of transplanted organs and tissues
0.927 0.073 0.000
Q50-Q56 Congenital malformations of genital organs
0.925 0.075 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.923 0.077 0.000
S72.00 Fracture of neck of femur (closed)
0.921 0.079 0.000
M47.8 Other spondylosis
0.918 0.082 0.000
A41 Other septicaemia
0.916 0.084 0.000
G30-G32 Other degenerative diseases of the nervous system
0.914 0.086 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.913 0.087 0.000
J90-J94 Other diseases of pleura
0.913 0.087 0.000
O16 Unspecified maternal hypertension
0.908 0.092 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.900 0.100 0.000
G90-G99 Other disorders of the nervous system
0.900 0.100 0.000
S91 Open wound of ankle and foot
0.900 0.100 0.000
O23 Infections of genito-urinary tract in pregnancy
0.898 0.102 0.000
Y40 Systemic antibiotics
0.896 0.104 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.894 0.106 0.000
S92 Fracture of foot, except ankle
0.893 0.107 0.000
L53 Other erythematous conditions
0.888 0.112 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.886 0.114 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.885 0.115 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.881 0.119 0.000
S10-S19 Injuries to the neck
0.877 0.123 0.000
M87 Osteonecrosis
0.876 0.124 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.876 0.124 0.000
M07 Psoriatic and enteropathic arthropathies
0.875 0.125 0.000
F20 Schizophrenia
0.874 0.125 0.000
S64 Injury of nerves at wrist and hand level
0.873 0.127 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.873 0.127 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.872 0.128 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.871 0.129 0.000
J92 Pleural plaque
0.868 0.132 0.000
L40-L45 Papulosquamous disorders
0.867 0.133 0.000
S20-S29 Injuries to the thorax
0.866 0.134 0.000
M54 Dorsalgia
0.864 0.136 0.000
S32 Fracture of lumbar spine and pelvis
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
S62.6 Fracture of other finger
0.863 0.137 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.863 0.137 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.860 0.140 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.857 0.143 0.000
L53.9 Erythematous condition, unspecified
0.857 0.143 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.856 0.144 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.851 0.149 0.000
G30 Alzheimer's disease
0.851 0.149 0.000
W00-W19 Falls
0.849 0.151 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.849 0.151 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.848 0.152 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.848 0.152 0.000
M47.1 Other spondylosis with myelopathy
0.847 0.153 0.000
Y40.0 Penicillins
0.846 0.154 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.845 0.155 0.000
J93 Pneumothorax
0.844 0.156 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.842 0.158 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.839 0.161 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.839 0.161 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.837 0.163 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.837 0.163 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.836 0.164 0.000
M47.2 Other spondylosis with radiculopathy
0.835 0.165 0.000
Y42.5 Other oestrogens and progestogens
0.835 0.165 0.000
M47.82 Other spondylosis (Cervical region)
0.833 0.167 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.831 0.169 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.829 0.171 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.829 0.171 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.825 0.175 0.000
F23 Acute and transient psychotic disorders
0.824 0.176 0.000
L40 Psoriasis
0.824 0.176 0.000
S62.60 Fracture of other finger (closed)
0.822 0.178 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.821 0.179 0.000
M48.0 Spinal stenosis
0.820 0.180 0.000
O41 Other disorders of amniotic fluid and membranes
0.819 0.181 0.000
M87.2 Osteonecrosis due to previous trauma
0.817 0.183 0.000
O85-O92 Complications predominantly related to the puerperium
0.814 0.186 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.812 0.187 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.812 0.188 0.000
F20.9 Schizophrenia, unspecified
0.811 0.189 0.000
L40.5 Arthropathic psoriasis
0.810 0.190 0.000
Y84.2 Radiological procedure and radiotherapy
0.809 0.191 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.809 0.191 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.809 0.191 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.804 0.196 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.804 0.196 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.804 0.196 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.803 0.197 0.000
F80-F89 Disorders of psychological development
0.801 0.199 0.000
M07.3 Other psoriatic arthropathies
0.799 0.200 0.000
T86.1 Kidney transplant failure and rejection
0.799 0.201 0.000
J92.0 Pleural plaque with presence of asbestos
0.799 0.201 0.000
S91.1 Open wound of toe(s) without damage to nail
0.799 0.201 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.799 0.201 0.000
G30.9 Alzheimer's disease, unspecified
0.798 0.202 0.000
J93.9 Pneumothorax, unspecified
0.797 0.203 0.000
Y00-Y09 Assault
0.797 0.203 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.796 0.204 0.000
X20-X29 Contact with venomous animals and plants
0.795 0.205 0.000
O21 Excessive vomiting in pregnancy
0.794 0.206 0.000
O48 Prolonged pregnancy
0.794 0.206 0.000
W50-W64 Exposure to animate mechanical forces
0.794 0.206 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.794 0.206 0.000
M54.9 Dorsalgia, unspecified
0.792 0.208 0.000
M06.0 Seronegative rheumatoid arthritis
0.791 0.209 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.789 0.211 0.000
S99 Other and unspecified injuries of ankle and foot
0.789 0.211 0.000
M54.2 Cervicalgia
0.786 0.214 0.000
L50 Urticaria
0.784 0.216 0.000
T88.4 Failed or difficult intubation
0.784 0.216 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.784 0.216 0.000
S72.1 Pertrochanteric fracture
0.783 0.216 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.782 0.217 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.782 0.218 0.000
S40-S49 Injuries to the shoulder and upper arm
0.781 0.219 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.781 0.219 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.781 0.219 0.000
F60-F69 Disorders of adult personality and behaviour
0.780 0.220 0.000
A80-A89 Viral infections of the central nervous system
0.779 0.221 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.779 0.221 0.000
Chapter VIII Diseases of the ear and mastoid process
0.778 0.222 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.777 0.223 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.777 0.223 0.000
M00-M03 Infectious arthropathies
0.776 0.224 0.000
O30 Multiple gestation
0.775 0.225 0.000
S12 Fracture of neck
0.775 0.225 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.775 0.225 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.774 0.226 0.000
V80-V89 Other land transport accidents
0.774 0.226 0.000
S92.3 Fracture of metatarsal bone
0.772 0.228 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.771 0.229 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.769 0.231 0.000
Q53 Undescended testicle
0.768 0.232 0.000
W20-W49 Exposure to inanimate mechanical forces
0.767 0.232 0.000
M53 Other dorsopathies, not elsewhere classified
0.767 0.233 0.000
M05 Seropositive rheumatoid arthritis
0.766 0.234 0.000
M06.3 Rheumatoid nodule
0.765 0.235 0.000
S65 Injury of blood vessels at wrist and hand level
0.764 0.236 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.764 0.236 0.000
B02 Zoster [herpes zoster]
0.763 0.237 0.000
J00-J06 Acute upper respiratory infections
0.760 0.240 0.000
S70 Superficial injury of hip and thigh
0.760 0.240 0.000
A31 Infection due to other mycobacteria
0.759 0.241 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.758 0.242 0.000
J86 Pyothorax
0.758 0.242 0.000
Q60-Q64 Congenital malformations of the urinary system
0.758 0.242 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.757 0.243 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.756 0.244 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.756 0.244 0.000
S72.4 Fracture of lower end of femur
0.756 0.244 0.000
S32.5 Fracture of pubis
0.756 0.244 0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)
0.755 0.245 0.000
O46.9 Antepartum haemorrhage, unspecified
0.755 0.245 0.000
J92.9 Pleural plaque without asbestos
0.752 0.248 0.000
T79-T79 Certain early complications of trauma
0.752 0.248 0.000
L05 Pilonidal cyst
0.750 0.250 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.749 0.251 0.000
L20-L30 Dermatitis and eczema
0.748 0.252 0.000
G95 Other diseases of spinal cord
0.748 0.252 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.747 0.253 0.000
G70-G73 Diseases of myoneural junction and muscle
0.747 0.253 0.000
S71 Open wound of hip and thigh
0.746 0.254 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.745 0.255 0.000
Y48 Anaesthetics and therapeutic gases
0.745 0.255 0.000
M86 Osteomyelitis
0.744 0.256 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.743 0.257 0.000
O80-O84 Delivery
0.743 0.257 0.000
T87 Complications peculiar to reattachment and amputation
0.742 0.258 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.742 0.258 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.741 0.259 0.000
Y42.7 Androgens and anabolic congeners
0.741 0.259 0.000
F70-F79 Mental retardation
0.741 0.259 0.000
S91.3 Open wound of other parts of foot
0.740 0.260 0.000
M91-M94 Chondropathies
0.736 0.263 0.000
S21 Open wound of thorax
0.736 0.264 0.000
M45 Ankylosing spondylitis
0.735 0.265 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.734 0.266 0.000
M80-M85 Disorders of bone density and structure
0.733 0.267 0.000
J90 Pleural effusion, not elsewhere classified
0.732 0.268 0.000
S20 Superficial injury of thorax
0.731 0.269 0.000
O20 Haemorrhage in early pregnancy
0.731 0.269 0.000
S90 Superficial injury of ankle and foot
0.731 0.269 0.000
S79 Other and unspecified injuries of hip and thigh
0.730 0.270 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.730 0.270 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.730 0.270 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.730 0.270 0.000
O42 Premature rupture of membranes
0.729 0.271 0.000
G83 Other paralytic syndromes
0.728 0.272 0.000
M89 Other disorders of bone
0.728 0.272 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.727 0.273 0.000
S62.7 Multiple fractures of fingers
0.726 0.274 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.725 0.275 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.725 0.275 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
V20-V29 Motorcycle rider injured in transport accident
0.724 0.276 0.000
Y43 Primarily systemic agents
0.723 0.277 0.000
M60-M63 Disorders of muscles
0.722 0.278 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.720 0.280 0.000
L10-L14 Bullous disorders
0.719 0.280 0.000
O43 Placental disorders
0.719 0.281 0.000
F20.0 Paranoid schizophrenia
0.719 0.281 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.719 0.281 0.000
X10-X19 Contact with heat and hot substances
0.718 0.282 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.717 0.283 0.000
T86.0 Bone-marrow transplant rejection
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.714 0.286 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.714 0.286 0.000
T92 Sequelae of injuries of upper limb
0.714 0.286 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.713 0.287 0.000
S62.4 Multiple fractures of metacarpal bones
0.713 0.287 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.713 0.287 0.000
M49 Spondylopathies in diseases classified elsewhere
0.712 0.287 0.000
H65-H75 Diseases of middle ear and mastoid
0.712 0.288 0.000
M51 Other intervertebral disk disorders
0.712 0.288 0.000
S60 Superficial injury of wrist and hand
0.711 0.289 0.000
M90 Osteopathies in diseases classified elsewhere
0.711 0.289 0.000
T88.5 Other complications of anaesthesia
0.710 0.290 0.000
J60-J70 Lung diseases due to external agents
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
S98 Traumatic amputation of ankle and foot
0.709 0.291 0.000
S97 Crushing injury of ankle and foot
0.709 0.291 0.000
S95 Injury of blood vessels at ankle and foot level
0.709 0.291 0.000
S94 Injury of nerves at ankle and foot level
0.709 0.291 0.000
Y45.1 Salicylates
0.708 0.292 0.000
S92.7 Multiple fractures of foot
0.708 0.292 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.707 0.293 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.707 0.293 0.000
B25-B34 Other viral diseases
0.706 0.294 0.000
S31 Open wound of abdomen, lower back and pelvis
0.705 0.295 0.000
S78 Traumatic amputation of hip and thigh
0.705 0.295 0.000
S77 Crushing injury of hip and thigh
0.705 0.295 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.705 0.295 0.000
S75 Injury of blood vessels at hip and thigh level
0.705 0.295 0.000
S74 Injury of nerves at hip and thigh level
0.705 0.295 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.705 0.295 0.000
S62.2 Fracture of first metacarpal bone
0.704 0.295 0.000
S32.4 Fracture of acetabulum
0.704 0.296 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.701 0.299 0.000
M54.8 Other dorsalgia
0.701 0.299 0.000
O32.0 Maternal care for unstable lie
0.701 0.299 0.000
S64.4 Injury of digital nerve of other finger
0.700 0.300 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.699 0.301 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.699 0.301 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.699 0.301 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.698 0.302 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.697 0.303 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.696 0.304 0.000
S92.2 Fracture of other tarsal bone(s)
0.695 0.305 0.000
M48.09 Spinal stenosis (Site unspecified)
0.694 0.306 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.694 0.306 0.000
M06.8 Other specified rheumatoid arthritis
0.694 0.306 0.000
M06.4 Inflammatory polyarthropathy
0.694 0.306 0.000
M06.2 Rheumatoid bursitis
0.694 0.306 0.000
M06.1 Adult-onset Still's disease
0.694 0.306 0.000
O15 Eclampsia
0.694 0.306 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.694 0.306 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.694 0.306 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.693 0.307 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.692 0.308 0.000
F30-F39 Mood [affective] disorders
0.692 0.308 0.000
W18 Other fall on same level
0.692 0.308 0.000
G58 Other mononeuropathies
0.692 0.308 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.692 0.308 0.000
S62.5 Fracture of thumb
0.691 0.308 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.691 0.308 0.000
Q35-Q37 Cleft lip and cleft palate
0.691 0.308 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.308 0.000
O26.9 Pregnancy-related condition, unspecified
0.692 0.308 0.000
S72.9 Fracture of femur, part unspecified
0.690 0.310 0.000
S72.8 Fractures of other parts of femur
0.690 0.310 0.000
S72.7 Multiple fractures of femur
0.690 0.310 0.000
O29 Complications of anaesthesia during pregnancy
0.690 0.310 0.000
O28 Abnormal findings on antenatal screening of mother
0.690 0.310 0.000
O22 Venous complications in pregnancy
0.690 0.310 0.000
O25 Malnutrition in pregnancy
0.690 0.310 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.690 0.310 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.310 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.688 0.312 0.000
B02.9 Zoster without complication
0.688 0.312 0.000
M54.22 Cervicalgia (Cervical region)
0.687 0.313 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.686 0.314 0.000
G82 Paraplegia and tetraplegia
0.686 0.314 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.686 0.314 0.000
O32.2 Maternal care for transverse and oblique lie
0.685 0.315 0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level
0.685 0.315 0.000
S62.1 Fracture of other carpal bone(s)
0.685 0.315 0.000
S92.30 Fracture of metatarsal bone (closed)
0.685 0.315 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
W10 Fall on and from stairs and steps
0.684 0.316 0.000
O14.9 Preeclampsia, unspecified
0.684 0.316 0.000
O45 Premature separation of placenta [abruptio placentae]
0.683 0.316 0.000
O33 Maternal care for known or suspected disproportion
0.683 0.316 0.000
O31 Complications specific to multiple gestation
0.683 0.316 0.000
O32.3 Maternal care for face, brow and chin presentation
0.683 0.317 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.682 0.318 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.682 0.318 0.000
T83.2 Mechanical complication of graft of urinary organ
0.682 0.318 0.000
A41.8 Other specified septicaemia
0.682 0.318 0.000
M87.9 Osteonecrosis, unspecified
0.681 0.319 0.000
A46 Erysipelas
0.681 0.319 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.680 0.320 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.680 0.320 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.680 0.320 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.680 0.320 0.000
S11 Open wound of neck
0.680 0.320 0.000
O41.0 Oligohydramnios
0.680 0.320 0.000
F99-F99 Unspecified mental disorder
0.680 0.320 0.000
B65-B83 Helminthiases
0.679 0.320 0.000
S32.50 Fracture of pubis (closed)
0.679 0.321 0.000
J91 Pleural effusion in conditions classified elsewhere
0.679 0.321 0.000
S69 Other and unspecified injuries of wrist and hand
0.678 0.321 0.000
S72.2 Subtrochanteric fracture
0.678 0.321 0.000
F25 Schizoaffective disorders
0.678 0.321 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.678 0.322 0.000
G90 Disorders of autonomic nervous system
0.678 0.322 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.678 0.322 0.000
S37 Injury of urinary and pelvic organs
0.678 0.322 0.000
S36 Injury of intra-abdominal organs
0.678 0.322 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.678 0.322 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.678 0.322 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.678 0.322 0.000
J00 Acute nasopharyngitis [common cold]
0.677 0.323 0.000
G31.8 Other specified degenerative diseases of nervous system
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.677 0.323 0.000
J86.9 Pyothorax without fistula
0.677 0.323 0.000
M47.86 Other spondylosis (Lumbar region)
0.677 0.323 0.000
J95-J99 Other diseases of the respiratory system
0.677 0.323 0.000
A48 Other bacterial diseases, not elsewhere classified
0.676 0.324 0.000
A44 Bartonellosis
0.676 0.324 0.000
A43 Nocardiosis
0.676 0.324 0.000
A42 Actinomycosis
0.676 0.324 0.000
A39 Meningococcal infection
0.676 0.324 0.000
A37 Whooping cough
0.676 0.324 0.000
A36 Diphtheria
0.676 0.324 0.000
A32 Listeriosis
0.676 0.324 0.000
A30 Leprosy [Hansen's disease]
0.676 0.324 0.000
A38 Scarlet fever
0.676 0.324 0.000
A35 Other tetanus
0.676 0.324 0.000
A34 Obstetrical tetanus
0.676 0.324 0.000
A33 Tetanus neonatorum
0.676 0.324 0.000
M48.9 Spondylopathy, unspecified
0.676 0.324 0.000
M48.8 Other specified spondylopathies
0.676 0.324 0.000
M48.4 Fatigue fracture of vertebra
0.676 0.324 0.000
M48.3 Traumatic spondylopathy
0.676 0.324 0.000
M48.2 Kissing spine
0.676 0.324 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.676 0.324 0.000
Q61 Cystic kidney disease
0.675 0.324 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.675 0.325 0.000
S93.0 Dislocation of ankle joint
0.673 0.327 0.000
S72.01 Fracture of neck of femur (open)
0.673 0.327 0.000
F00 Dementia in Alzheimer's disease
0.673 0.327 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.673 0.327 0.000
M50 Cervical disk disorders
0.672 0.328 0.000
S10 Superficial injury of neck
0.672 0.328 0.000
T66-T78 Other and unspecified effects of external causes
0.672 0.328 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.672 0.328 0.000
Q54 Hypospadias
0.671 0.329 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
L54 Erythema in diseases classified elsewhere
0.668 0.332 0.000
L51 Erythema multiforme
0.668 0.332 0.000
L52 Erythema nodosum
0.668 0.332 0.000
O42.9 Premature rupture of membranes, unspecified
0.668 0.332 0.000
F28 Other nonorganic psychotic disorders
0.667 0.333 0.000
F24 Induced delusional disorder
0.667 0.333 0.000
F21 Schizotypal disorder
0.667 0.333 0.000
Y40.8 Other systemic antibiotics
0.667 0.333 0.000
L50.8 Other urticaria
0.667 0.333 0.000
M65-M68 Disorders of synovium and tendon
0.667 0.333 0.000
O44 Placenta praevia
0.665 0.335 0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.665 0.335 0.000
T86.4 Liver transplant failure and rejection
0.665 0.335 0.000
T86.3 Heart-lung transplant failure and rejection
0.665 0.335 0.000
T86.2 Heart transplant failure and rejection
0.665 0.335 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.664 0.335 0.000
B01 Varicella [chickenpox]
0.664 0.336 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.663 0.337 0.000
Q55 Other congenital malformations of male genital organs
0.663 0.337 0.000
Q52 Other congenital malformations of female genitalia
0.663 0.337 0.000
Y00 Assault by blunt object
0.663 0.337 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.663 0.337 0.000
Y42.9 Other and unspecified hormone antagonists
0.662 0.338 0.000
Y42.4 Oral contraceptives
0.662 0.338 0.000
Y42.2 Antithyroid drugs
0.662 0.338 0.000
Y42.1 Thyroid hormones and substitutes
0.662 0.338 0.000
S67 Crushing injury of wrist and hand
0.662 0.338 0.000
B07 Viral warts
0.660 0.340 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.660 0.340 0.000
T23 Burn and corrosion of wrist and hand
0.660 0.340 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.659 0.341 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.659 0.341 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.659 0.341 0.000
M54.29 Cervicalgia-Site unspe
0.659 0.341 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.658 0.342 0.000
M47.84 Other spondylosis (Thoracic region)
0.658 0.342 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.658 0.342 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.658 0.342 0.000
U80 Agent resistant to penicillin and related antibiotics
0.657 0.343 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.657 0.343 0.000
S72.3 Fracture of shaft of femur
0.657 0.343 0.000
A41.4 Septicaemia due to anaerobes
0.656 0.343 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.656 0.343 0.000
O21.0 Mild hyperemesis gravidarum
0.656 0.344 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.656 0.344 0.000
J93.0 Spontaneous tension pneumothorax
0.656 0.344 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.656 0.344 0.000
Q53.1 Undescended testicle, unilateral
0.655 0.345 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.655 0.345 0.000
S72.10 Pertrochanteric fracture (closed)
0.655 0.345 0.000
G91 Hydrocephalus
0.655 0.345 0.000
S92.4 Fracture of great toe
0.654 0.346 0.000
W15 Fall from cliff
0.654 0.346 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.653 0.347 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.653 0.347 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.653 0.347 0.000
M46 Other inflammatory spondylopathies
0.652 0.347 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.652 0.347 0.000
S32.0 Fracture of lumbar vertebra
0.652 0.348 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.652 0.348 0.000
Q23 Congenital malformations of aortic and mitral valves
0.652 0.348 0.000
X60-X84 Intentional self-harm
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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