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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75548506
log Bayes Factor = 21.2834
Chromosome 3   position 35,532,707  (GRCh37) Explore rs75548506 on Ensembl!
Variant rs75548506 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.997 0.003 0.000
E65-E68 Obesity and other hyperalimentation
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
N81 Female genital prolapse
0.997 0.003 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.997 0.003 0.000
E66 Obesity
0.996 0.004 0.000
I10-I15 Hypertensive diseases
0.994 0.006 0.000
E66.9 Obesity, unspecified
0.994 0.006 0.000
N81.6 Rectocele
0.991 0.009 0.000
J44 Other chronic obstructive pulmonary disease
0.991 0.009 0.000
I10 Essential (primary) hypertension
0.991 0.009 0.000
R00 Abnormalities of heart beat
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.986 0.014 0.000
R00.1 Bradycardia, unspecified
0.984 0.016 0.000
Chapter I Certain infectious and parasitic diseases
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.977 0.023 0.000
M70-M79 Other soft tissue disorders
0.971 0.029 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.970 0.030 0.000
F30-F39 Mood [affective] disorders
0.966 0.034 0.000
M20-M25 Other joint disorders
0.960 0.040 0.000
S00-S09 Injuries to the head
0.954 0.046 0.000
M05-M14 Inflammatory polyarthropathies
0.953 0.047 0.000
R42 Dizziness and giddiness
0.945 0.055 0.000
R07 Pain in throat and chest
0.940 0.060 0.000
M15-M19 Arthrosis
0.937 0.063 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.936 0.064 0.000
N81.1 Cystocele
0.935 0.065 0.000
N92 Excessive, frequent and irregular menstruation
0.929 0.071 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.926 0.074 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.925 0.075 0.000
I50 Heart failure
0.923 0.077 0.000
J47 Bronchiectasis
0.922 0.078 0.000
N89 Other noninflammatory disorders of vagina
0.918 0.082 0.000
R41.0 Disorientation, unspecified
0.918 0.082 0.000
E66.8 Other obesity
0.918 0.082 0.000
R05 Cough
0.914 0.086 0.000
M50-M54 Other dorsopathies
0.913 0.087 0.000
F32 Depressive episode
0.912 0.088 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.909 0.091 0.000
A00-A09 Intestinal infectious diseases
0.906 0.094 0.000
M75 Shoulder lesions
0.901 0.099 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.896 0.104 0.000
Z02 Examination and encounter for administrative purposes
0.895 0.105 0.000
M10 Gout
0.893 0.107 0.000
N81.4 Uterovaginal prolapse, unspecified
0.890 0.110 0.000
Z30 Contraceptive management
0.890 0.110 0.000
Chapter VIII Diseases of the ear and mastoid process
0.887 0.113 0.000
M18 Arthrosis of first carpometacarpal joint
0.886 0.114 0.000
I35 Nonrheumatic aortic valve disorders
0.885 0.115 0.000
J45 Asthma
0.885 0.115 0.000
S80-S89 Injuries to the knee and lower leg
0.881 0.119 0.000
I44 Atrioventricular and left bundle-branch block
0.879 0.121 0.000
M25 Other joint disorders, not elsewhere classified
0.877 0.123 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.876 0.124 0.000
M54 Dorsalgia
0.876 0.124 0.000
F31 Bipolar affective disorder
0.875 0.125 0.000
R07.2 Precordial pain
0.875 0.125 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.874 0.126 0.000
E00-E07 Disorders of thyroid gland
0.874 0.126 0.000
Z02.8 Other examinations for administrative purposes
0.874 0.126 0.000
A30-A49 Other bacterial diseases
0.872 0.128 0.000
B95-B98 Bacterial, viral and other infectious agents
0.871 0.129 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.862 0.138 0.000
J43 Emphysema
0.859 0.141 0.000
S02 Fracture of skull and facial bones
0.859 0.141 0.000
J60-J70 Lung diseases due to external agents
0.859 0.141 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.858 0.142 0.000
M19 Other arthrosis
0.858 0.142 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.857 0.143 0.000
I50.9 Heart failure, unspecified
0.854 0.146 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.852 0.148 0.000
N99-N99 Other disorders of the genitourinary system
0.850 0.150 0.000
M10.9 Gout, unspecified
0.849 0.150 0.000
N17-N19 Renal failure
0.849 0.151 0.000
M86-M90 Other osteopathies
0.845 0.155 0.000
Z12 Special screening examination for neoplasms
0.844 0.156 0.000
R00.0 Tachycardia, unspecified
0.843 0.157 0.000
R50-R69 General symptoms and signs
0.842 0.158 0.000
M75.1 Rotator cuff syndrome
0.838 0.162 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.837 0.163 0.000
J45.9 Asthma, unspecified
0.836 0.164 0.000
S01 Open wound of head
0.836 0.164 0.000
S40-S49 Injuries to the shoulder and upper arm
0.835 0.165 0.000
I51 Complications and ill-defined descriptions of heart disease
0.833 0.167 0.000
Chapter XX External causes of morbidity and mortality
0.832 0.168 0.000
M40-M43 Deforming dorsopathies
0.831 0.169 0.000
M80-M85 Disorders of bone density and structure
0.830 0.170 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.830 0.170 0.000
I45 Other conduction disorders
0.830 0.170 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.829 0.171 0.000
M22 Disorders of patella
0.828 0.172 0.000
E10-E14 Diabetes mellitus
0.826 0.174 0.000
N93 Other abnormal uterine and vaginal bleeding
0.826 0.174 0.000
T79-T79 Certain early complications of trauma
0.825 0.175 0.000
M65-M68 Disorders of synovium and tendon
0.820 0.180 0.000
H65-H75 Diseases of middle ear and mastoid
0.819 0.181 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.818 0.182 0.000
M54.9 Dorsalgia, unspecified
0.818 0.182 0.000
I20-I25 Ischaemic heart diseases
0.818 0.182 0.000
B25-B34 Other viral diseases
0.816 0.184 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.816 0.184 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.814 0.186 0.000
M45-M49 Spondylopathies
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.807 0.193 0.000
M10.99 Gout, unspecified (Site unspecified)
0.805 0.195 0.000
F32.0 Mild depressive episode
0.805 0.195 0.000
S20-S29 Injuries to the thorax
0.802 0.198 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.801 0.199 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.799 0.201 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.799 0.201 0.000
N81.3 Complete uterovaginal prolapse
0.798 0.202 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.797 0.203 0.000
M19.9 Arthrosis, unspecified
0.796 0.204 0.000
I35.1 Aortic (valve) insufficiency
0.795 0.205 0.000
F32.9 Depressive episode, unspecified
0.794 0.206 0.000
A41 Other septicaemia
0.793 0.207 0.000
S50-S59 Injuries to the elbow and forearm
0.792 0.208 0.000
M54.5 Low back pain
0.791 0.209 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.790 0.210 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.787 0.213 0.000
N81.2 Incomplete uterovaginal prolapse
0.786 0.214 0.000
Chapter VI Diseases of the nervous system
0.786 0.214 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.785 0.215 0.000
N10-N16 Renal tubulo-interstitial diseases
0.785 0.215 0.000
J30-J39 Other diseases of upper respiratory tract
0.785 0.215 0.000
S06 Intracranial injury
0.782 0.218 0.000
F43 Reaction to severe stress, and adjustment disorders
0.780 0.220 0.000
M11 Other crystal arthropathies
0.780 0.220 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.779 0.221 0.000
N25-N29 Other disorders of kidney and ureter
0.778 0.222 0.000
I44.0 Atrioventricular block, first degree
0.778 0.222 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.777 0.223 0.000
R51 Headache
0.777 0.223 0.000
M75.4 Impingement syndrome of shoulder
0.777 0.223 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.776 0.224 0.000
M35 Other systemic involvement of connective tissue
0.774 0.226 0.000
J95-J99 Other diseases of the respiratory system
0.772 0.228 0.000
E20-E35 Disorders of other endocrine glands
0.771 0.229 0.000
A08 Viral and other specified intestinal infections
0.770 0.230 0.000
M79.6 Pain in limb
0.769 0.231 0.000
R07.4 Chest pain, unspecified
0.768 0.232 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.767 0.233 0.000
M91-M94 Chondropathies
0.766 0.234 0.000
S02.4 Fracture of malar and maxillary bones
0.766 0.234 0.000
Chapter VII Diseases of the eye and adnexa
0.765 0.235 0.000
G40-G47 Episodic and paroxysmal disorders
0.765 0.235 0.000
J43.9 Emphysema, unspecified
0.759 0.241 0.000
J42 Unspecified chronic bronchitis
0.759 0.241 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.757 0.243 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.756 0.244 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.755 0.245 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.755 0.245 0.000
A04 Other bacterial intestinal infections
0.754 0.246 0.000
I51.7 Cardiomegaly
0.753 0.247 0.000
M79.0 Rheumatism, unspecified
0.752 0.247 0.000
T91 Sequelae of injuries of neck and trunk
0.751 0.249 0.000
F31.9 Bipolar affective disorder, unspecified
0.751 0.249 0.000
I42 Cardiomyopathy
0.750 0.250 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
N81.8 Other female genital prolapse
0.749 0.251 0.000
M25.9 Joint disorder, unspecified
0.746 0.254 0.000
F33 Recurrent depressive disorder
0.746 0.254 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.746 0.254 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.745 0.255 0.000
S60-S69 Injuries to the wrist and hand
0.745 0.255 0.000
I46 Cardiac arrest
0.744 0.256 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.744 0.256 0.000
R55 Syncope and collapse
0.744 0.256 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.743 0.256 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.743 0.257 0.000
R50 Fever of unknown origin
0.743 0.257 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.743 0.257 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.743 0.257 0.000
I33 Acute and subacute endocarditis
0.742 0.258 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.740 0.260 0.000
J90-J94 Other diseases of pleura
0.740 0.260 0.000
G40 Epilepsy
0.739 0.261 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.738 0.262 0.000
E11 Non-insulin-dependent diabetes mellitus
0.738 0.262 0.000
H65 Nonsuppurative otitis media
0.737 0.263 0.000
S82 Fracture of lower leg, including ankle
0.737 0.263 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.736 0.264 0.000
Z39 Postpartum care and examination
0.735 0.265 0.000
Chapter XI Diseases of the digestive system
0.733 0.267 0.000
N93.0 Postcoital and contact bleeding
0.733 0.267 0.000
E04 Other non-toxic goitre
0.733 0.267 0.000
J46 Status asthmaticus
0.732 0.268 0.000
N00-N08 Glomerular diseases
0.731 0.269 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.730 0.270 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.729 0.271 0.000
H60-H62 Diseases of external ear
0.729 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
T93 Sequelae of injuries of lower limb
0.726 0.274 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.726 0.274 0.000
Z04 Examination and observation for other reasons
0.726 0.274 0.000
M24 Other specific joint derangements
0.725 0.275 0.000
M21 Other acquired deformities of limbs
0.724 0.276 0.000
M54.59 Low back pain (Site unspecified)
0.722 0.278 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.722 0.278 0.000
M25.4 Effusion of joint
0.722 0.278 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.722 0.278 0.000
M31 Other necrotising vasculopathies
0.722 0.278 0.000
Z30.3 Menstrual extraction
0.720 0.280 0.000
L20-L30 Dermatitis and eczema
0.720 0.280 0.000
M05 Seropositive rheumatoid arthritis
0.719 0.281 0.000
T90 Sequelae of injuries of head
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
S80 Superficial injury of lower leg
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
N17 Acute renal failure
0.715 0.285 0.000
E67 Other hyperalimentation
0.715 0.285 0.000
E68 Sequelae of hyperalimentation
0.715 0.285 0.000
E65 Localised adiposity
0.715 0.285 0.000
N81.9 Female genital prolapse, unspecified
0.714 0.285 0.000
N81.0 Female urethrocele
0.714 0.285 0.000
N98 Complications associated with artificial fertilisation
0.714 0.285 0.000
N91 Absent, scanty and rare menstruation
0.714 0.285 0.000
N82 Fistulae involving female genital tract
0.714 0.285 0.000
N96 Habitual aborter
0.714 0.285 0.000
I45.1 Other and unspecified right bundle-branch block
0.715 0.285 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.714 0.286 0.000
E66.1 Drug-induced obesity
0.714 0.286 0.000
E66.0 Obesity due to excess calories
0.714 0.286 0.000
I15 Secondary hypertension
0.713 0.287 0.000
I13 Hypertensive heart and renal disease
0.713 0.287 0.000
I11 Hypertensive heart disease
0.713 0.287 0.000
F40 Phobic anxiety disorders
0.712 0.288 0.000
T92 Sequelae of injuries of upper limb
0.711 0.289 0.000
I50.1 Left ventricular failure
0.711 0.289 0.000
I52 Other heart disorders in diseases classified elsewhere
0.710 0.290 0.000
I48 Atrial fibrillation and flutter
0.710 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.710 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.710 0.290 0.000
I40 Acute myocarditis
0.710 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.710 0.290 0.000
I37 Pulmonary valve disorders
0.710 0.290 0.000
I36 Nonrheumatic tricuspid valve disorders
0.710 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.710 0.290 0.000
I30 Acute pericarditis
0.710 0.290 0.000
I60-I69 Cerebrovascular diseases
0.710 0.290 0.000
I34 Nonrheumatic mitral valve disorders
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.707 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.292 0.000
F80-F89 Disorders of psychological development
0.707 0.292 0.000
F70-F79 Mental retardation
0.707 0.292 0.000
F60-F69 Disorders of adult personality and behaviour
0.707 0.292 0.000
T66-T78 Other and unspecified effects of external causes
0.707 0.293 0.000
R46 Symptoms and signs involving appearance and behaviour
0.707 0.293 0.000
R45 Symptoms and signs involving emotional state
0.707 0.293 0.000
R43 Disturbances of smell and taste
0.707 0.293 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.706 0.294 0.000
M75.3 Calcific tendinitis of shoulder
0.706 0.294 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B65-B83 Helminthiases
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
B15-B19 Viral hepatitis
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
Z34 Supervision of normal pregnancy
0.704 0.296 0.000
D50-D53 Nutritional anaemias
0.703 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.703 0.297 0.000
I73 Other peripheral vascular diseases
0.703 0.297 0.000
N80 Endometriosis
0.702 0.298 0.000
M54.1 Radiculopathy
0.702 0.298 0.000
M25.5 Pain in joint
0.700 0.300 0.000
M88 Paget's disease of bone [osteitis deformans]
0.700 0.300 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.700 0.300 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.699 0.301 0.000
I20 Angina pectoris
0.699 0.301 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.698 0.302 0.000
B34 Viral infection of unspecified site
0.697 0.303 0.000
I50.0 Congestive heart failure
0.697 0.303 0.000
R07.3 Other chest pain
0.697 0.303 0.000
M76 Enthesopathies of lower limb, excluding foot
0.696 0.304 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.696 0.304 0.000
M71 Other bursopathies
0.696 0.304 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.696 0.304 0.000
M43 Other deforming dorsopathies
0.696 0.304 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.695 0.305 0.000
M13 Other arthritis
0.695 0.305 0.000
Chapter XXII Codes for special purposes
0.694 0.305 0.000
E05.9 Thyrotoxicosis, unspecified
0.694 0.306 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.694 0.306 0.000
I25 Chronic ischaemic heart disease
0.694 0.306 0.000
N92.3 Ovulation bleeding
0.693 0.307 0.000
S01.5 Open wound of lip and oral cavity
0.693 0.307 0.000
N13 Obstructive and reflux uropathy
0.693 0.307 0.000
F38 Other mood [affective] disorders
0.693 0.307 0.000
F34 Persistent mood [affective] disorders
0.693 0.307 0.000
F30 Manic episode
0.693 0.307 0.000
F39 Unspecified mood [affective] disorder
0.693 0.307 0.000
K40-K46 Hernia
0.693 0.307 0.000
Z01.8 Other specified special examinations
0.692 0.308 0.000
I44.7 Left bundle-branch block, unspecified
0.692 0.308 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.690 0.309 0.000
M79.8 Other specified soft tissue disorders
0.690 0.310 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.690 0.310 0.000
M81 Osteoporosis without pathological fracture
0.690 0.310 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.688 0.312 0.000
M34 Systemic sclerosis
0.688 0.312 0.000
M33 Dermatopolymyositis
0.688 0.312 0.000
M32 Systemic lupus erythematosus
0.688 0.312 0.000
M30 Polyarteritis nodosa and related conditions
0.688 0.312 0.000
M22.4 Chondromalacia patellae
0.688 0.312 0.000
M77 Other enthesopathies
0.687 0.312 0.000
J09-J18 Influenza and pneumonia
0.687 0.313 0.000
E11.9 Without complications
0.686 0.314 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.686 0.314 0.000
M06 Other rheumatoid arthritis
0.685 0.315 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.685 0.315 0.000
Z36 Antenatal screening
0.684 0.316 0.000
S08 Traumatic amputation of part of head
0.684 0.316 0.000
S07 Crushing injury of head
0.684 0.316 0.000
S05 Injury of eye and orbit
0.684 0.316 0.000
S04 Injury of cranial nerves
0.684 0.316 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.684 0.316 0.000
M14 Arthropathies in other diseases classified elsewhere
0.683 0.317 0.000
M12 Other specific arthropathies
0.683 0.317 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.683 0.317 0.000
M08 Juvenile arthritis
0.683 0.317 0.000
I44.1 Atrioventricular block, second degree
0.683 0.317 0.000
R74 Abnormal serum enzyme levels
0.683 0.317 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.682 0.318 0.000
R04 Haemorrhage from respiratory passages
0.682 0.318 0.000
N97 Female infertility
0.681 0.319 0.000
J40 Bronchitis, not specified as acute or chronic
0.681 0.319 0.000
I77 Other disorders of arteries and arterioles
0.680 0.319 0.000
I05-I09 Chronic rheumatic heart diseases
0.680 0.320 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.680 0.320 0.000
I74 Arterial embolism and thrombosis
0.680 0.320 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.679 0.321 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.679 0.321 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.678 0.322 0.000
S02.1 Fracture of base of skull
0.678 0.322 0.000
Z35 Supervision of high-risk pregnancy
0.678 0.322 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.678 0.322 0.000
J34 Other disorders of nose and nasal sinuses
0.677 0.323 0.000
N92.6 Irregular menstruation, unspecified
0.676 0.323 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.676 0.324 0.000
M72 Fibroblastic disorders
0.675 0.324 0.000
S09 Other and unspecified injuries of head
0.675 0.325 0.000
R07.1 Chest pain on breathing
0.674 0.326 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.674 0.326 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.673 0.327 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.673 0.327 0.000
R50.9 Fever, unspecified
0.672 0.328 0.000
I38 Endocarditis, valve unspecified
0.672 0.328 0.000
M15 Polyarthrosis
0.672 0.328 0.000
R41.2 Retrograde amnesia
0.671 0.329 0.000
R41.1 Anterograde amnesia
0.671 0.329 0.000
M07 Psoriatic and enteropathic arthropathies
0.671 0.329 0.000
M65 Synovitis and tenosynovitis
0.671 0.329 0.000
M22.8 Other disorders of patella
0.670 0.330 0.000
J69 Pneumonitis due to solids and liquids
0.670 0.330 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.668 0.332 0.000
R09.2 Respiratory arrest
0.667 0.333 0.000
M10.96 Gout, unspecified (Lower leg)
0.667 0.333 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.667 0.333 0.000
N92.5 Other specified irregular menstruation
0.666 0.334 0.000
N92.2 Excessive menstruation at puberty
0.666 0.334 0.000
I22 Subsequent myocardial infarction
0.666 0.334 0.000
M79.7 Fibromyalgia
0.665 0.335 0.000
B35-B49 Mycoses
0.665 0.335 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.664 0.336 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.664 0.336 0.000
Z10 Routine general health check-up of defined subpopulation
0.664 0.336 0.000
I70 Atherosclerosis
0.663 0.336 0.000
Z38 Liveborn infants according to place of birth
0.663 0.337 0.000
Z32 Pregnancy examination and test
0.663 0.337 0.000
Z31 Procreative management
0.663 0.337 0.000
I12 Hypertensive renal disease
0.663 0.337 0.000
M87 Osteonecrosis
0.661 0.338 0.000
N86 Erosion and ectropion of cervix uteri
0.661 0.339 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.660 0.340 0.000
F43.1 Posttraumatic stress disorder
0.660 0.340 0.000
N92.4 Excessive bleeding in the premenopausal period
0.660 0.340 0.000
H53-H54 Visual disturbances and blindness
0.659 0.341 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.658 0.342 0.000
N89.7 Haematocolpos
0.658 0.342 0.000
N89.6 Tight hymenal ring
0.658 0.342 0.000
N89.5 Stricture and atresia of vagina
0.658 0.342 0.000
N89.4 Leukoplakia of vagina
0.658 0.342 0.000
N89.3 Dysplasia of vagina, unspecified
0.658 0.342 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.658 0.342 0.000
N89.1 Moderate vaginal dysplasia
0.658 0.342 0.000
N89.0 Mild vaginal dysplasia
0.658 0.342 0.000
E06 Thyroiditis
0.658 0.342 0.000
Z33 Pregnant state, incidental
0.657 0.343 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.656 0.344 0.000
R02 Gangrene, not elsewhere classified
0.656 0.344 0.000
R07.0 Pain in throat
0.655 0.345 0.000
M11.2 Other chondrocalcinosis
0.655 0.345 0.000
S01.2 Open wound of nose
0.655 0.345 0.000
R09.1 Pleurisy
0.655 0.345 0.000
M53 Other dorsopathies, not elsewhere classified
0.654 0.346 0.000
F32.8 Other depressive episodes
0.654 0.346 0.000
F32.1 Moderate depressive episode
0.654 0.346 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.654 0.346 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.654 0.346 0.000
M23 Internal derangement of knee
0.654 0.346 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.653 0.347 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.653 0.347 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.652 0.347 0.000
F43.2 Adjustment disorders
0.652 0.348 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.652 0.348 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.348 0.000
T95 Sequelae of burns, corrosions and frostbite
0.652 0.348 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.652 0.348 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.652 0.348 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.652 0.348 0.000
R79 Other abnormal findings of blood chemistry
0.651 0.349 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.650 0.350 0.000
S40 Superficial injury of shoulder and upper arm
0.650 0.350 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.650 0.350 0.000
A07 Other protozoal intestinal diseases
0.649 0.350 0.000
A06 Amoebiasis
0.649 0.350 0.000
A05 Other bacterial foodborne intoxications
0.649 0.350 0.000
A03 Shigellosis
0.649 0.350 0.000
A02 Other Salmonella infections
0.649 0.350 0.000
A01 Typhoid and paratyphoid fevers
0.649 0.350 0.000
A00 Cholera
0.649 0.350 0.000
H73 Other disorders of tympanic membrane
0.649 0.351 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.648 0.352 0.000
H74 Other disorders of middle ear and mastoid
0.647 0.352 0.000
R52 Pain, not elsewhere classified
0.647 0.353 0.000
M75.8 Other shoulder lesions
0.646 0.354 0.000
M75.9 Shoulder lesion, unspecified
0.646 0.354 0.000
M75.2 Bicipital tendinitis
0.646 0.354 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.646 0.354 0.000
D60-D64 Aplastic and other anaemias
0.646 0.354 0.000
Z57 Occupational exposure to risk-factors
0.645 0.354 0.000
V10-V19 Pedal cyclist injured in transport accident
0.645 0.355 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.644 0.356 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.644 0.356 0.000
M79.69 Pain in limb (Site unspecified)
0.644 0.356 0.000
M79.9 Soft tissue disorder, unspecified
0.642 0.357 0.000
M79.5 Residual foreign body in soft tissue
0.642 0.357 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.642 0.357 0.000
M79.3 Panniculitis, unspecified
0.642 0.357 0.000
M79.2 Neuralgia and neuritis, unspecified
0.642 0.357 0.000
M79.1 Myalgia
0.642 0.357 0.000
Z02.9 Examination for administrative purposes, unspecified
0.642 0.358 0.000
Z02.7 Issue of medical certificate
0.642 0.358 0.000
Z02.6 Examination for insurance purposes
0.642 0.358 0.000
Z02.5 Examination for participation in sport
0.642 0.358 0.000
Z02.4 Examination for driving licence
0.642 0.358 0.000
Z02.3 Examination for recruitment to armed forces
0.642 0.358 0.000
Z02.2 Examination for admission to residential institution
0.642 0.358 0.000
Z02.1 Pre-employment examination
0.642 0.358 0.000
Z02.0 Examination for admission to educational institution
0.642 0.358 0.000
D51 Vitamin B12 deficiency anaemia
0.642 0.358 0.000
N13.3 Other and unspecified hydronephrosis
0.641 0.359 0.000
N18 Chronic renal failure
0.640 0.360 0.000
R76 Other abnormal immunological findings in serum
0.640 0.360 0.000
M10.4 Other secondary gout
0.640 0.360 0.000
M10.3 Gout due to impairment of renal function
0.640 0.360 0.000
M10.2 Drug-induced gout
0.640 0.360 0.000
M10.1 Lead-induced gout
0.640 0.360 0.000
M10.0 Idiopathic gout
0.640 0.360 0.000
H65.3 Chronic mucoid otitis media
0.640 0.360 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.639 0.361 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.639 0.361 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.639 0.361 0.000
N87 Dysplasia of cervix uteri
0.639 0.361 0.000
S42 Fracture of shoulder and upper arm
0.639 0.361 0.000
W20-W49 Exposure to inanimate mechanical forces
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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