TreeWAS – Variant ID: rs7599488

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.799	0.201	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.789	0.211	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.772	0.228	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.765	0.235	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.751	0.249	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.735	0.265	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.728	0.272	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.708	0.292	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.705	0.295	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.689	0.311	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.677	0.323	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.672	0.328	0.000
T43.2 Other and unspecified antidepressants	0.665	0.335	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.657	0.343	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.657	0.343	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.650	0.350	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.644	0.355	0.000
T39.1 4-Aminophenol derivatives	0.637	0.363	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.624	0.376	0.000
T38.1 Thyroid hormones and substitutes	0.622	0.378	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.621	0.379	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.613	0.387	0.000
T36 Poisoning by systemic antibiotics	0.610	0.390	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.603	0.397	0.000
T39.0 Salicylates	0.602	0.398	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.596	0.404	0.000
T43.9 Psychotropic drug, unspecified	0.594	0.406	0.000
T42.4 Benzodiazepines	0.593	0.407	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.584	0.416	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.573	0.427	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.573	0.427	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.570	0.430	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.568	0.432	0.000
T47.2 Stimulant laxatives	0.566	0.434	0.000
T39.4 Antirheumatics, not elsewhere classified	0.566	0.434	0.000
T39.2 Pyrazolone derivatives	0.566	0.434	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.553	0.447	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.544	0.456	0.000
T38.9 Other and unspecified hormone antagonists	0.538	0.462	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.538	0.462	0.000
T38.7 Androgens and anabolic congeners	0.538	0.462	0.000
T38.5 Other oestrogens and progestogens	0.538	0.462	0.000
T38.4 Oral contraceptives	0.538	0.462	0.000
T38.2 Antithyroid drugs	0.538	0.462	0.000
T38.0 Glucocorticoids and synthetic analogues	0.538	0.462	0.000
T47.0 Histamine H(2)-receptor antagonists	0.536	0.464	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.533	0.466	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.533	0.467	0.000
T43.6 Psychostimulants with abuse potential	0.528	0.472	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.527	0.473	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.527	0.473	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.527	0.473	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.527	0.473	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.527	0.473	0.000
T44.0 Anticholinesterase agents	0.527	0.473	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.526	0.474	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.524	0.476	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.522	0.478	0.000
T46.7 Peripheral vasodilators	0.522	0.478	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.522	0.478	0.000
T47.4 Other laxatives	0.515	0.485	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.513	0.487	0.000
T50.4 Drugs affecting uric acid metabolism	0.511	0.489	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.509	0.491	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.502	0.498	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.501	0.499	0.000
T50.1 Loop [high-ceiling] diuretics	0.497	0.503	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.494	0.506	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.494	0.506	0.000
T47.7 Emetics	0.494	0.506	0.000
T47.6 Antidiarrhoeal drugs	0.494	0.506	0.000
T47.5 Digestants	0.494	0.506	0.000
T47.3 Saline and osmotic laxatives	0.494	0.506	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.492	0.508	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.483	0.517	0.000
T36.0 Penicillins	0.475	0.525	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.474	0.526	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.471	0.529	0.000
T42.3 Barbiturates	0.471	0.529	0.000
T42.2 Succinimides and oxazolidinediones	0.471	0.529	0.000
T50.7 Analeptics and opioid receptor antagonists	0.466	0.534	0.000
T50.5 Appetite depressants	0.466	0.534	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.466	0.534	0.000
T50.0 Mineralocorticoids and their antagonists	0.466	0.534	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.463	0.537	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.462	0.538	0.000
T48.5 Anti-common-cold drugs	0.462	0.538	0.000
T48.4 Expectorants	0.462	0.538	0.000
T48.3 Antitussives	0.462	0.538	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.462	0.538	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.462	0.538	0.000
T48.0 Oxytocic drugs	0.462	0.538	0.000
T46.1 Calcium-channel blockers	0.448	0.551	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.445	0.555	0.000
T37.5 Antiviral drugs	0.445	0.555	0.000
T37.4 Anthelminthics	0.445	0.555	0.000
T37.3 Other antiprotozoal drugs	0.445	0.555	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.445	0.555	0.000
T37.1 Antimycobacterial drugs	0.445	0.555	0.000
T37.0 Sulphonamides	0.445	0.555	0.000
T36.3 Macrolides	0.438	0.562	0.000
T36.9 Systemic antibiotic, unspecified	0.437	0.562	0.000
T36.8 Other systemic antibiotics	0.437	0.562	0.000
T36.7 Antifungal antibiotics, systemically used	0.437	0.562	0.000
T36.6 Rifamycins	0.437	0.562	0.000
T36.5 Aminoglycosides	0.437	0.562	0.000
T36.2 Chloramphenicol group	0.437	0.562	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.437	0.562	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.436	0.564	0.000
T36.4 Tetracyclines	0.436	0.564	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.430	0.569	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.428	0.572	0.000
S64.4 Injury of digital nerve of other finger	0.426	0.574	0.000
T41.5 Therapeutic gases	0.411	0.589	0.000
T41.4 Anaesthetic, unspecified	0.411	0.589	0.000
T41.3 Local anaesthetics	0.411	0.589	0.000
T41.2 Other and unspecified general anaesthetics	0.411	0.589	0.000
T41.1 Intravenous anaesthetics	0.411	0.589	0.000
T41.0 Inhaled anaesthetics	0.411	0.589	0.000
T49.9 Topical agent, unspecified	0.411	0.589	0.000
T49.8 Other topical agents	0.411	0.589	0.000
T49.7 Dental drugs, topically applied	0.411	0.589	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.411	0.589	0.000
T49.5 Ophthalmological drugs and preparations	0.411	0.589	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.411	0.589	0.000
T49.3 Emollients, demulcents and protectants	0.411	0.589	0.000
T49.2 Local astringents and local detergents	0.411	0.589	0.000
T49.1 Antipruritics	0.411	0.589	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.411	0.589	0.000
T42.0 Hydantoin derivatives	0.407	0.593	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.402	0.598	0.000
T50.8 Diagnostic agents	0.381	0.618	0.000
T45.5 Anticoagulants	0.371	0.629	0.000
T45.0 Antiallergic and antiemetic drugs	0.369	0.631	0.000
T45.4 Iron and its compounds	0.368	0.632	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.359	0.641	0.000
T45.8 Other primarily systemic and haematological agents	0.359	0.641	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.359	0.641	0.000
T45.6 Fibrinolysis-affecting drugs	0.359	0.641	0.000
T45.3 Enzymes, not elsewhere classified	0.359	0.641	0.000
T42.1 Iminostilbenes	0.345	0.655	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.311	0.688	0.000
T45.2 Vitamins, not elsewhere classified	0.301	0.698	0.000
I21.4 Acute subendocardial myocardial infarction	0.251	0.749	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.243	0.757	0.000
I21 Acute myocardial infarction	0.241	0.759	0.000
I21.9 Acute myocardial infarction, unspecified	0.235	0.765	0.000
S64 Injury of nerves at wrist and hand level	0.224	0.776	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.220	0.780	0.000
I20-I25 Ischaemic heart diseases	0.218	0.782	0.000
I22 Subsequent myocardial infarction	0.210	0.790	0.000
I24 Other acute ischaemic heart diseases	0.199	0.801	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.197	0.803	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.190	0.810	0.000
S64.1 Injury of median nerve at wrist and hand level	0.190	0.810	0.000
I25 Chronic ischaemic heart disease	0.189	0.811	0.000
I25.2 Old myocardial infarction	0.183	0.817	0.000
T40.1 Heroin	0.181	0.819	0.000
I24.8 Other forms of acute ischaemic heart disease	0.179	0.821	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.174	0.825	0.000
T40.8 Lysergide [LSD]	0.174	0.825	0.000
T40.7 Cannabis (derivatives)	0.174	0.825	0.000
T40.0 Opium	0.174	0.825	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.173	0.826	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.173	0.827	0.000
T40.3 Methadone	0.173	0.827	0.000
T40.5 Cocaine	0.169	0.831	0.000
I25.3 Aneurysm of heart	0.167	0.833	0.000
S60-S69 Injuries to the wrist and hand	0.163	0.837	0.000
S61.0 Open wound of finger(s) without damage to nail	0.162	0.838	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.160	0.839	0.000
S64.8 Injury of other nerves at wrist and hand level	0.160	0.839	0.000
I22.8 Subsequent myocardial infarction of other sites	0.160	0.840	0.000
S64.3 Injury of digital nerve of thumb	0.156	0.844	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.154	0.846	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.153	0.847	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.153	0.847	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.151	0.849	0.000
I23 Certain current complications following acute myocardial infarction	0.151	0.849	0.000
S61 Open wound of wrist and hand	0.150	0.850	0.000
I25.1 Atherosclerotic heart disease	0.149	0.851	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.148	0.852	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.148	0.852	0.000
I25.6 Silent myocardial ischaemia	0.147	0.853	0.000
T40.4 Other synthetic narcotics	0.142	0.857	0.000
I25.4 Coronary artery aneurysm	0.137	0.863	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.130	0.870	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.126	0.874	0.000
S63.2 Multiple dislocations of fingers	0.126	0.874	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.126	0.874	0.000
S65 Injury of blood vessels at wrist and hand level	0.121	0.879	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.120	0.880	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.120	0.880	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.120	0.880	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.119	0.881	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.119	0.881	0.000
I24.1 Dressler's syndrome	0.116	0.884	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.116	0.884	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.112	0.888	0.000
T40.6 Other and unspecified narcotics	0.111	0.888	0.000
S63.1 Dislocation finger	0.110	0.890	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.110	0.890	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.108	0.891	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.108	0.891	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.108	0.891	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.108	0.891	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.108	0.891	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.108	0.891	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.108	0.891	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.108	0.891	0.000
S63.5 Sprain and strain of wrist	0.103	0.896	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.103	0.897	0.000
I23.8 Other current complications following acute myocardial infarction	0.103	0.897	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.102	0.897	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.102	0.898	0.000
T40.2 Other opioids	0.101	0.899	0.000
S60 Superficial injury of wrist and hand	0.100	0.900	0.000
S63.6 Sprain and strain of finger(s)	0.092	0.908	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.091	0.909	0.000
S61.7 Multiple open wounds of wrist and hand	0.091	0.909	0.000
S65.1 Injury of radial artery at wrist and hand level	0.089	0.910	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.087	0.913	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.087	0.913	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.087	0.913	0.000
S65.3 Injury of deep palmar arch	0.087	0.913	0.000
S65.2 Injury of superficial palmar arch	0.087	0.913	0.000
S65.4 Injury of blood vessel(s) of thumb	0.086	0.913	0.000
S65.5 Injury of blood vessel(s) of other finger	0.085	0.915	0.000
S63.0 Dislocation of wrist	0.083	0.917	0.000
S68 Traumatic amputation of wrist and hand	0.081	0.919	0.000
S60.8 Other superficial injuries of wrist and hand	0.081	0.919	0.000
S69 Other and unspecified injuries of wrist and hand	0.080	0.920	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.079	0.921	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.078	0.922	0.000
S67 Crushing injury of wrist and hand	0.074	0.925	0.001
S60.9 Superficial injury of wrist and hand, unspecified	0.074	0.926	0.000
S60.1 Contusion of finger(s) with damage to nail	0.073	0.927	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.067	0.933	0.001
S61.8 Open wound of other parts of wrist and hand	0.066	0.934	0.000
S60.2 Contusion of other parts of wrist and hand	0.064	0.936	0.000
S60.0 Contusion of finger(s) without damage to nail	0.063	0.937	0.000
S69.8 Other specified injuries of wrist and hand	0.061	0.939	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.058	0.941	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.058	0.941	0.000
S68.4 Traumatic amputation of hand at wrist level	0.058	0.941	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.058	0.941	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.056	0.944	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.053	0.946	0.001
S62 Fracture at wrist and hand level	0.054	0.946	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.053	0.947	0.000
S61.1 Open wound of finger(s) with damage to nail	0.051	0.949	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.051	0.949	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.050	0.950	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.049	0.951	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.045	0.955	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.043	0.957	0.000
S62.6 Fracture of other finger	0.041	0.959	0.000
S69.7 Multiple injuries of wrist and hand	0.040	0.960	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.039	0.961	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.039	0.961	0.000
S62.7 Multiple fractures of fingers	0.039	0.961	0.000
S69.9 Unspecified injury of wrist and hand	0.038	0.961	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.038	0.962	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.038	0.962	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.038	0.962	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.038	0.962	0.000
S62.61 Fracture of other finger (open)	0.038	0.962	0.000
S62.1 Fracture of other carpal bone(s)	0.037	0.963	0.000
S62.4 Multiple fractures of metacarpal bones	0.035	0.965	0.000
I25.5 Ischaemic cardiomyopathy	0.034	0.965	0.001
E04.9 Non-toxic goitre, unspecified	0.000	0.965	0.035
I24.9 Acute ischaemic heart disease, unspecified	0.033	0.967	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.032	0.968	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.031	0.969	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.031	0.969	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.031	0.969	0.000
S62.2 Fracture of first metacarpal bone	0.030	0.970	0.000
S62.70 Multiple fractures of fingers (closed)	0.030	0.970	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.030	0.970	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.972	0.028
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.027	0.973	0.000
S62.3 Fracture of other metacarpal bone	0.027	0.973	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.027	0.973	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.026	0.974	0.000
I20 Angina pectoris	0.026	0.974	0.000
T83.2 Mechanical complication of graft of urinary organ	0.026	0.974	0.000
S62.71 Multiple fractures of fingers (open)	0.025	0.974	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.025	0.974	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.025	0.975	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.025	0.975	0.000
S62.21 Fracture of first metacarpal bone (open)	0.022	0.978	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.022	0.978	0.000
S62.31 Fracture of other metacarpal bone (open)	0.020	0.980	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.020	0.980	0.000
S62.5 Fracture of thumb	0.019	0.981	0.000
I20.9 Angina pectoris, unspecified	0.017	0.983	0.000
T51.0 Ethanol	0.015	0.985	0.000
S52.1 Fracture of upper end of radius	0.000	0.985	0.014
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.014	0.986	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.013	0.986	0.000
T51 Toxic effect of alcohol	0.014	0.986	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.014	0.986	0.000
N81.8 Other female genital prolapse	0.000	0.987	0.013
S67.0 Crushing injury of thumb and other finger(s)	0.010	0.987	0.003
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.013	0.987	0.000
I45.1 Other and unspecified right bundle-branch block	0.013	0.987	0.000
I20.0 Unstable angina	0.012	0.988	0.000
S52.11 Fracture of upper end of radius (open)	0.000	0.988	0.011
S62.60 Fracture of other finger (closed)	0.011	0.989	0.000
T14 Injury of unspecified body region	0.011	0.989	0.000
T65 Toxic effect of other and unspecified substances	0.011	0.989	0.000
T33-T35 Frostbite	0.010	0.989	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.010	0.989	0.000
T63 Toxic effect of contact with venomous animals	0.010	0.990	0.000
T00-T07 Injuries involving multiple body regions	0.010	0.990	0.000
T13 Other injuries of lower limb, level unspecified	0.010	0.990	0.000
T62 Toxic effect of other noxious substances eaten as food	0.010	0.990	0.000
T14.1 Open wound of unspecified body region	0.010	0.990	0.000
T51.8 Other alcohols	0.010	0.990	0.000
T51.3 Fusel oil	0.010	0.990	0.000
T51.2 2-Propanol	0.010	0.990	0.000
T51.1 Methanol	0.010	0.990	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.010	0.990	0.000
T60 Toxic effect of pesticides	0.010	0.990	0.000
T57 Toxic effect of other inorganic substances	0.010	0.990	0.000
T56 Toxic effect of metals	0.010	0.990	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.010	0.990	0.000
T52 Toxic effect of organic solvents	0.010	0.990	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.010	0.990	0.000
T55 Toxic effect of soaps and detergents	0.010	0.990	0.000
T08 Fracture of spine, level unspecified	0.010	0.990	0.000
T11 Other injuries of upper limb, level unspecified	0.010	0.990	0.000
I45 Other conduction disorders	0.010	0.990	0.000
T14.0 Superficial injury of unspecified body region	0.010	0.990	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.009	0.991	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.009	0.991	0.000
T12 Fracture of lower limb, level unspecified	0.009	0.991	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.009	0.991	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.009	0.991	0.000
T10 Fracture of upper limb, level unspecified	0.009	0.991	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.009	0.991	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.009	0.991	0.000
T09 Other injuries of spine and trunk, level unspecified	0.009	0.991	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.009	0.991	0.000
T58 Toxic effect of carbon monoxide	0.009	0.991	0.000
T54 Toxic effect of corrosive substances	0.009	0.991	0.000
I45.6 Preexcitation syndrome	0.009	0.991	0.000
T79-T79 Certain early complications of trauma	0.009	0.991	0.000
I45.5 Other specified heart block	0.009	0.991	0.000
E78.0 Pure hypercholesterolaemia	0.009	0.991	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.009	0.991	0.000
S62.51 Fracture of thumb (open)	0.008	0.991	0.000
T65.9 Toxic effect of unspecified substance	0.009	0.991	0.000
T59 Toxic effect of other gases, fumes and vapours	0.008	0.991	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.008	0.991	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.008	0.991	0.001
C77.0 Lymph nodes of head, face and neck	0.008	0.992	0.000
T02 Fractures involving multiple body regions	0.008	0.992	0.000
T01 Open wounds involving multiple body regions	0.008	0.992	0.000
D33.3 Cranial nerves	0.008	0.992	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.008	0.992	0.000
T14.2 Fracture of unspecified body region	0.008	0.992	0.000
T14.8 Other injuries of unspecified body region	0.008	0.992	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.008	0.992	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.008	0.992	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.008	0.992	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.008	0.992	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.008	0.992	0.000
T65.8 Toxic effect of other specified substances	0.008	0.992	0.000
T65.6 Paints and dyes, not elsewhere classified	0.008	0.992	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.008	0.992	0.000
T65.4 Carbon disulphide	0.008	0.992	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.008	0.992	0.000
T65.2 Tobacco and nicotine	0.008	0.992	0.000
T65.1 Strychnine and its salts	0.008	0.992	0.000
T65.0 Cyanides	0.008	0.992	0.000
T28 Burn and corrosion of other internal organs	0.008	0.992	0.000
T27 Burn and corrosion of respiratory tract	0.008	0.992	0.000
T26 Burn and corrosion confined to eye and adnexa	0.008	0.992	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.008	0.992	0.000
T34 Frostbite with tissue necrosis	0.008	0.992	0.000
T33 Superficial frostbite	0.008	0.992	0.000
I45.3 Trifascicular block	0.008	0.992	0.000
T63.8 Toxic effect of contact with other venomous animals	0.008	0.992	0.000
T63.6 Toxic effect of contact with other marine animals	0.008	0.992	0.000
T63.5 Toxic effect of contact with fish	0.008	0.992	0.000
T63.3 Venom of spider	0.008	0.992	0.000
T63.2 Venom of scorpion	0.008	0.992	0.000
T63.1 Venom of other reptiles	0.008	0.992	0.000
T63.0 Snake venom	0.008	0.992	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.008	0.992	0.000
T05 Traumatic amputations involving multiple body regions	0.008	0.992	0.000
T04 Crushing injuries involving multiple body regions	0.008	0.992	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.008	0.992	0.000
T07 Unspecified multiple injuries	0.008	0.992	0.000
T62.9 Noxious substance eaten as food, unspecified	0.008	0.992	0.000
T17 Foreign body in respiratory tract	0.008	0.992	0.000
S02 Fracture of skull and facial bones	0.008	0.992	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.007	0.992	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.007	0.992	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.007	0.992	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.007	0.992	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.007	0.992	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.007	0.992	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.007	0.992	0.000
T62.8 Other specified noxious substances eaten as food	0.007	0.992	0.000
T62.2 Other ingested (parts of) plant(s)	0.007	0.992	0.000
T62.1 Ingested berries	0.007	0.992	0.000
T62.0 Ingested mushrooms	0.007	0.992	0.000
T11.1 Open wound of upper limb, level unspecified	0.007	0.992	0.000
T29 Burns and corrosions of multiple body regions	0.007	0.993	0.000
T09.3 Injury of spinal cord, level unspecified	0.007	0.993	0.000
T52.9 Organic solvent, unspecified	0.007	0.993	0.000
T52.8 Other organic solvents	0.007	0.993	0.000
T52.4 Ketones	0.007	0.993	0.000
T52.3 Glycols	0.007	0.993	0.000
T52.2 Homologues of benzene	0.007	0.993	0.000
T52.1 Benzene	0.007	0.993	0.000
T52.0 Petroleum products	0.007	0.993	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.007	0.993	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.007	0.993	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.007	0.993	0.000
T53.5 Chlorofluorocarbons	0.007	0.993	0.000
T53.4 Dichloromethane	0.007	0.993	0.000
T53.3 Tetrachloroethylene	0.007	0.993	0.000
T53.2 Trichloroethylene	0.007	0.993	0.000
T53.1 Chloroform	0.007	0.993	0.000
T53.0 Carbon tetrachloride	0.007	0.993	0.000
T56.9 Metal, unspecified	0.007	0.993	0.000
T56.7 Beryllium and its compounds	0.007	0.993	0.000
T56.6 Tin and its compounds	0.007	0.993	0.000
T56.5 Zinc and its compounds	0.007	0.993	0.000
T56.4 Copper and its compounds	0.007	0.993	0.000
T56.3 Cadmium and its compounds	0.007	0.993	0.000
T56.2 Chromium and its compounds	0.007	0.993	0.000
T56.1 Mercury and its compounds	0.007	0.993	0.000
T56.0 Lead and its compounds	0.007	0.993	0.000
T57.9 Inorganic substance, unspecified	0.007	0.993	0.000
T57.8 Other specified inorganic substances	0.007	0.993	0.000
T57.3 Hydrogen cyanide	0.007	0.993	0.000
T57.2 Manganese and its compounds	0.007	0.993	0.000
T57.1 Phosphorus and its compounds	0.007	0.993	0.000
T57.0 Arsenic and its compounds	0.007	0.993	0.000
T60.9 Pesticide, unspecified	0.007	0.993	0.000
T60.8 Other pesticides	0.007	0.993	0.000
T60.4 Rodenticides	0.007	0.993	0.000
T60.3 Herbicides and fungicides	0.007	0.993	0.000
T60.2 Other insecticides	0.007	0.993	0.000
T60.1 Halogenated insecticides	0.007	0.993	0.000
T60.0 Organophosphate and carbamate insecticides	0.007	0.993	0.000
T61.9 Toxic effect of unspecified seafood	0.007	0.993	0.000
T61.8 Toxic effect of other seafoods	0.007	0.993	0.000
T61.2 Other fish and shellfish poisoning	0.007	0.993	0.000
T61.1 Scombroid fish poisoning	0.007	0.993	0.000
T61.0 Ciguatera fish poisoning	0.007	0.993	0.000
T56.8 Other metals	0.007	0.993	0.000
T63.4 Venom of other arthropods	0.007	0.993	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.007	0.993	0.000
S02.8 Fractures of other skull and facial bones	0.007	0.993	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.007	0.993	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.007	0.993	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.007	0.993	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.007	0.993	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.007	0.993	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.007	0.993	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.007	0.993	0.000
T32 Corrosions classified according to extent of body surface involved	0.007	0.993	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.007	0.993	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.007	0.993	0.000
I45.0 Right fascicular block	0.007	0.993	0.000
T51.9 Alcohol, unspecified	0.007	0.993	0.000
G40.9 Epilepsy, unspecified	0.007	0.993	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.007	0.993	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.007	0.993	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.007	0.993	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.007	0.993	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.007	0.993	0.000
T09.1 Open wound of trunk, level unspecified	0.007	0.993	0.000
T30 Burn and corrosion, body region unspecified	0.007	0.993	0.000
S02.5 Fracture of tooth	0.007	0.993	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.007	0.993	0.000
T54.2 Corrosive acids and acid-like substances	0.007	0.993	0.000
T54.1 Other corrosive organic compounds	0.007	0.993	0.000
T54.0 Phenol and phenol homologues	0.007	0.993	0.000
T02.5 Fractures involving multiple regions of both lower limbs	0.007	0.993	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.007	0.993	0.000
T13.1 Open wound of lower limb, level unspecified	0.007	0.993	0.000
S02.2 Fracture of nasal bones	0.007	0.993	0.000
T09.0 Superficial injury of trunk, level unspecified	0.007	0.993	0.000
S02.50 Fracture of tooth (closed)	0.007	0.993	0.000
T01.3 Open wounds involving multiple regions of lower limb(s)	0.006	0.993	0.000
S00-S09 Injuries to the head	0.007	0.993	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.006	0.993	0.000
I45.2 Bifascicular block	0.006	0.993	0.000
S02.7 Multiple fractures involving skull and facial bones	0.006	0.993	0.000
T59.9 Gases, fumes and vapours, unspecified	0.006	0.993	0.000
T00 Superficial injuries involving multiple body regions	0.006	0.993	0.000
T14.9 Injury, unspecified	0.006	0.993	0.000
S10-S19 Injuries to the neck	0.006	0.994	0.000
I45.9 Conduction disorder, unspecified	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations