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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76037241
log Bayes Factor = 15.2229
Chromosome 18   position 3,178,541  (GRCh37) Explore rs76037241 on Ensembl!
Variant rs76037241 is part of Cluster X0155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
Z87 Personal history of other diseases and conditions
0.993 0.007 0.000
I25 Chronic ischaemic heart disease
0.993 0.007 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.987 0.013 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
N73 Other female pelvic inflammatory diseases
0.984 0.016 0.000
Z85 Personal history of malignant neoplasm
0.983 0.017 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.982 0.018 0.000
B95-B98 Bacterial, viral and other infectious agents
0.981 0.019 0.000
N73.6 Female pelvic peritoneal adhesions
0.980 0.020 0.000
I30-I52 Other forms of heart disease
0.978 0.022 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.975 0.025 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.975 0.025 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.968 0.032 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.966 0.034 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.966 0.034 0.000
Z87.8 Personal history of other specified conditions
0.957 0.043 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.955 0.045 0.000
Z50 Care involving use of rehabilitation procedures
0.950 0.050 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.945 0.055 0.000
N40-N51 Diseases of male genital organs
0.944 0.056 0.000
I50 Heart failure
0.936 0.064 0.000
Z46 Fitting and adjustment of other devices
0.935 0.065 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.933 0.067 0.000
N30-N39 Other diseases of urinary system
0.929 0.071 0.000
O00-O08 Pregnancy with abortive outcome
0.926 0.074 0.000
I73 Other peripheral vascular diseases
0.924 0.076 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.923 0.077 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.918 0.082 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.918 0.082 0.000
K13 Other diseases of lip and oral mucosa
0.912 0.088 0.000
I60-I69 Cerebrovascular diseases
0.909 0.091 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.908 0.092 0.000
I21 Acute myocardial infarction
0.907 0.093 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.906 0.094 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.905 0.095 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.903 0.097 0.000
Z95.0 Presence of cardiac pacemaker
0.901 0.099 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.900 0.100 0.000
Z46.6 Fitting and adjustment of urinary device
0.898 0.102 0.000
Chapter VIII Diseases of the ear and mastoid process
0.897 0.103 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.895 0.105 0.000
N32 Other disorders of bladder
0.893 0.107 0.000
K90-K93 Other diseases of the digestive system
0.893 0.107 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.887 0.113 0.000
K55-K64 Other diseases of intestines
0.886 0.114 0.000
I73.9 Peripheral vascular disease, unspecified
0.884 0.116 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.878 0.122 0.000
N99-N99 Other disorders of the genitourinary system
0.877 0.123 0.000
Z85.6 Personal history of leukaemia
0.875 0.125 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.874 0.126 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.872 0.128 0.000
K08 Other disorders of teeth and supporting structures
0.870 0.130 0.000
Chapter XXII Codes for special purposes
0.870 0.130 0.000
N32.8 Other specified disorders of bladder
0.867 0.133 0.000
I51 Complications and ill-defined descriptions of heart disease
0.866 0.134 0.000
I77 Other disorders of arteries and arterioles
0.865 0.135 0.000
Chapter II Neoplasms
0.865 0.135 0.000
K02 Dental caries
0.864 0.136 0.000
O80-O84 Delivery
0.863 0.137 0.000
I50.0 Congestive heart failure
0.862 0.138 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.860 0.140 0.000
N41 Inflammatory diseases of prostate
0.859 0.141 0.000
K60 Fissure and fistula of anal and rectal regions
0.858 0.142 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.858 0.142 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.856 0.144 0.000
R94 Abnormal results of function studies
0.854 0.146 0.000
I05-I09 Chronic rheumatic heart diseases
0.854 0.146 0.000
Y86 Sequelae of other accidents
0.853 0.147 0.000
N42 Other disorders of prostate
0.852 0.148 0.000
O02 Other abnormal products of conception
0.850 0.150 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.849 0.151 0.000
S40-S49 Injuries to the shoulder and upper arm
0.848 0.152 0.000
I74 Arterial embolism and thrombosis
0.846 0.154 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.844 0.156 0.000
I49 Other cardiac arrhythmias
0.843 0.157 0.000
R07 Pain in throat and chest
0.842 0.158 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.842 0.158 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.838 0.162 0.000
Z50.5 Speech therapy
0.835 0.165 0.000
S20-S29 Injuries to the thorax
0.833 0.167 0.000
K82 Other diseases of gallbladder
0.832 0.168 0.000
I21.4 Acute subendocardial myocardial infarction
0.830 0.170 0.000
I67 Other cerebrovascular diseases
0.830 0.170 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.829 0.171 0.000
N10-N16 Renal tubulo-interstitial diseases
0.828 0.172 0.000
R00 Abnormalities of heart beat
0.827 0.173 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.824 0.176 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.822 0.178 0.000
N35 Urethral stricture
0.820 0.179 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.820 0.180 0.000
K60.3 Anal fistula
0.818 0.182 0.000
K81 Cholecystitis
0.814 0.186 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.812 0.187 0.000
K08.3 Retained dental root
0.812 0.188 0.000
K83 Other diseases of biliary tract
0.809 0.191 0.000
Z94 Transplanted organ and tissue status
0.808 0.192 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.806 0.194 0.000
I70 Atherosclerosis
0.805 0.195 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.803 0.197 0.000
Z95.1 Presence of aortocoronary bypass graft
0.801 0.199 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.799 0.201 0.000
O02.1 Missed abortion
0.796 0.204 0.000
I50.1 Left ventricular failure
0.794 0.206 0.000
Z40 Prophylactic surgery
0.794 0.206 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.790 0.210 0.000
K61 Abscess of anal and rectal regions
0.790 0.210 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
I45 Other conduction disorders
0.787 0.212 0.000
N70 Salpingitis and oophoritis
0.787 0.213 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
K92 Other diseases of digestive system
0.787 0.213 0.000
N45 Orchitis and epididymitis
0.786 0.214 0.000
K02.9 Dental caries, unspecified
0.786 0.214 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.785 0.215 0.000
O80 Single spontaneous delivery
0.783 0.217 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.782 0.218 0.000
I34 Nonrheumatic mitral valve disorders
0.782 0.218 0.000
Z52 Donors of organs and tissues
0.782 0.218 0.000
R30-R39 Symptoms and signs involving the urinary system
0.780 0.220 0.000
Z49 Care involving dialysis
0.780 0.220 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.779 0.221 0.000
Z50.2 Alcohol rehabilitation
0.777 0.223 0.000
I51.9 Heart disease, unspecified
0.775 0.225 0.000
I67.9 Cerebrovascular disease, unspecified
0.775 0.225 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.775 0.225 0.000
I35 Nonrheumatic aortic valve disorders
0.775 0.225 0.000
R07.4 Chest pain, unspecified
0.772 0.228 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.771 0.229 0.000
R79 Other abnormal findings of blood chemistry
0.769 0.231 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.767 0.233 0.000
I61 Intracerebral haemorrhage
0.765 0.235 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.765 0.235 0.000
D00-D09 In situ neoplasms
0.763 0.237 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.763 0.237 0.000
Z97 Presence of other devices
0.762 0.238 0.000
N42.1 Congestion and haemorrhage of prostate
0.762 0.238 0.000
H65-H75 Diseases of middle ear and mastoid
0.761 0.239 0.000
R00.2 Palpitations
0.761 0.239 0.000
O03 Spontaneous abortion
0.760 0.240 0.000
I25.2 Old myocardial infarction
0.759 0.241 0.000
I77.6 Arteritis, unspecified
0.759 0.241 0.000
A30-A49 Other bacterial diseases
0.758 0.242 0.000
Z91.6 Personal history of other physical trauma
0.755 0.245 0.000
D60-D64 Aplastic and other anaemias
0.754 0.246 0.000
Y43 Primarily systemic agents
0.753 0.247 0.000
Z22 Carrier of infectious disease
0.753 0.247 0.000
R07.2 Precordial pain
0.752 0.248 0.000
S60-S69 Injuries to the wrist and hand
0.752 0.248 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.751 0.248 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.750 0.250 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.750 0.250 0.000
K82.8 Other specified diseases of gallbladder
0.748 0.252 0.000
L60-L75 Disorders of skin appendages
0.747 0.253 0.000
I62 Other nontraumatic intracranial haemorrhage
0.747 0.253 0.000
H90-H95 Other disorders of ear
0.746 0.254 0.000
K92.0 Haematemesis
0.746 0.254 0.000
I49.9 Cardiac arrhythmia, unspecified
0.745 0.255 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.744 0.256 0.000
N35.9 Urethral stricture, unspecified
0.743 0.257 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.742 0.258 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
K90 Intestinal malabsorption
0.742 0.258 0.000
C44 Other malignant neoplasms of skin
0.741 0.259 0.000
Z83 Family history of other specific disorders
0.741 0.259 0.000
Y95 Nosocomial condition
0.741 0.259 0.000
I50.9 Heart failure, unspecified
0.740 0.260 0.000
N40 Hyperplasia of prostate
0.740 0.260 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.738 0.262 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.737 0.263 0.000
A80-A89 Viral infections of the central nervous system
0.737 0.263 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.736 0.264 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.736 0.264 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.735 0.265 0.000
Z48 Other surgical follow-up care
0.734 0.266 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.734 0.266 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.734 0.266 0.000
C43 Malignant melanoma of skin
0.732 0.267 0.000
R94.5 Abnormal results of liver function studies
0.732 0.268 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.732 0.268 0.000
N41.1 Chronic prostatitis
0.731 0.269 0.000
N32.0 Bladder-neck obstruction
0.731 0.269 0.000
Z42 Follow-up care involving plastic surgery
0.730 0.270 0.000
I33 Acute and subacute endocarditis
0.729 0.270 0.000
Chapter V Mental and behavioural disorders
0.729 0.271 0.000
N17-N19 Renal failure
0.729 0.271 0.000
I08 Multiple valve diseases
0.726 0.274 0.000
Y88 Sequelae of surgical and medical care as external cause
0.725 0.275 0.000
K10 Other diseases of jaws
0.724 0.276 0.000
S50-S59 Injuries to the elbow and forearm
0.724 0.276 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.724 0.276 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.722 0.278 0.000
K61.0 Anal abscess
0.721 0.279 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.720 0.279 0.000
N32.1 Vesicointestinal fistula
0.720 0.280 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.720 0.280 0.000
K60.2 Anal fissure, unspecified
0.719 0.281 0.000
Z87.0 Personal history of diseases of the respiratory system
0.719 0.281 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.719 0.281 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.718 0.282 0.000
Z50.0 Cardiac rehabilitation
0.718 0.282 0.000
S42 Fracture of shoulder and upper arm
0.717 0.283 0.000
I78 Diseases of capillaries
0.717 0.283 0.000
K07 Dentofacial anomalies [including malocclusion]
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.717 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
K12 Stomatitis and related lesions
0.713 0.287 0.000
Z50.1 Other physical therapy
0.713 0.287 0.000
I51.7 Cardiomegaly
0.713 0.287 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.712 0.288 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.712 0.288 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.712 0.288 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.712 0.288 0.000
I25.6 Silent myocardial ischaemia
0.712 0.288 0.000
I25.5 Ischaemic cardiomyopathy
0.712 0.288 0.000
I25.4 Coronary artery aneurysm
0.712 0.288 0.000
I25.3 Aneurysm of heart
0.712 0.288 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.712 0.288 0.000
O04 Medical abortion
0.712 0.288 0.000
O80.0 Spontaneous vertex delivery
0.711 0.289 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.710 0.289 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.710 0.290 0.000
N76 Other inflammation of vagina and vulva
0.710 0.290 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.710 0.290 0.000
N71 Inflammatory disease of uterus, except cervix
0.710 0.290 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
Z54 Convalescence
0.708 0.292 0.000
Z44 Fitting and adjustment of external prosthetic device
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.708 0.292 0.000
I72 Other aneurysm
0.708 0.292 0.000
S70-S79 Injuries to the hip and thigh
0.707 0.292 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
B15-B19 Viral hepatitis
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
N60-N64 Disorders of breast
0.707 0.293 0.000
T66-T78 Other and unspecified effects of external causes
0.707 0.293 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.705 0.294 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.705 0.294 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.705 0.294 0.000
N73.5 Female pelvic peritonitis, unspecified
0.705 0.294 0.000
N73.4 Female chronic pelvic peritonitis
0.705 0.294 0.000
N73.3 Female acute pelvic peritonitis
0.705 0.294 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.705 0.294 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.705 0.294 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.705 0.294 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.705 0.295 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.705 0.295 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.705 0.295 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.296 0.000
S90-S99 Injuries to the ankle and foot
0.704 0.296 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.704 0.296 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.703 0.297 0.000
W20-W49 Exposure to inanimate mechanical forces
0.703 0.297 0.000
I24 Other acute ischaemic heart diseases
0.703 0.297 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.701 0.299 0.000
I48 Atrial fibrillation and flutter
0.701 0.299 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.701 0.299 0.000
I41 Myocarditis in diseases classified elsewhere
0.701 0.299 0.000
I40 Acute myocarditis
0.701 0.299 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.701 0.299 0.000
I37 Pulmonary valve disorders
0.701 0.299 0.000
I36 Nonrheumatic tricuspid valve disorders
0.701 0.299 0.000
I32 Pericarditis in diseases classified elsewhere
0.701 0.299 0.000
I30 Acute pericarditis
0.701 0.299 0.000
I38 Endocarditis, valve unspecified
0.701 0.299 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
Y83.8 Other surgical procedures
0.701 0.299 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.700 0.300 0.000
O85-O92 Complications predominantly related to the puerperium
0.699 0.301 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.699 0.301 0.000
K09 Cysts of oral region, not elsewhere classified
0.699 0.301 0.000
K03 Other diseases of hard tissues of teeth
0.699 0.301 0.000
K00 Disorders of tooth development and eruption
0.699 0.301 0.000
N30 Cystitis
0.698 0.302 0.000
K83.8 Other specified diseases of biliary tract
0.697 0.303 0.000
R94.3 Abnormal results of cardiovascular function studies
0.696 0.304 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.694 0.306 0.000
T79-T79 Certain early complications of trauma
0.694 0.306 0.000
T33-T35 Frostbite
0.694 0.306 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.694 0.306 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.694 0.306 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
T00-T07 Injuries involving multiple body regions
0.694 0.306 0.000
S10-S19 Injuries to the neck
0.694 0.306 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.694 0.306 0.000
K86 Other diseases of pancreas
0.693 0.307 0.000
K05 Gingivitis and periodontal diseases
0.693 0.307 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.693 0.307 0.000
U80 Agent resistant to penicillin and related antibiotics
0.692 0.307 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.692 0.308 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.692 0.308 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.692 0.308 0.000
Z45 Adjustment and management of implanted device
0.691 0.308 0.000
O00 Ectopic pregnancy
0.691 0.309 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.690 0.310 0.000
R01 Cardiac murmurs and other cardiac sounds
0.687 0.312 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.686 0.314 0.000
Z41 Procedures for purposes other than remedying health state
0.686 0.314 0.000
R45 Symptoms and signs involving emotional state
0.686 0.314 0.000
I71 Aortic aneurysm and dissection
0.685 0.314 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.684 0.315 0.000
Z95.3 Presence of xenogenic heart valve
0.684 0.315 0.000
Z22.3 Carrier of other specified bacterial diseases
0.684 0.316 0.000
I49.8 Other specified cardiac arrhythmias
0.684 0.316 0.000
B35-B49 Mycoses
0.683 0.317 0.000
R02 Gangrene, not elsewhere classified
0.683 0.317 0.000
K04 Diseases of pulp and periapical tissues
0.683 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.318 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.681 0.318 0.000
Z50.6 Orthoptic training
0.681 0.319 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.681 0.319 0.000
Z50.3 Drug rehabilitation
0.681 0.319 0.000
N41.0 Acute prostatitis
0.681 0.319 0.000
K14 Diseases of tongue
0.681 0.319 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
I22 Subsequent myocardial infarction
0.680 0.320 0.000
I34.0 Mitral (valve) insufficiency
0.679 0.321 0.000
T18 Foreign body in alimentary tract
0.678 0.321 0.000
Z91.5 Personal history of self-harm
0.678 0.322 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.677 0.323 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.677 0.323 0.000
N46 Male infertility
0.677 0.323 0.000
N44 Torsion of testis
0.677 0.323 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.676 0.324 0.000
K81.0 Acute cholecystitis
0.676 0.324 0.000
C64-C68 Malignant neoplasms of urinary tract
0.676 0.324 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.675 0.325 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.675 0.325 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.325 0.000
D03 Melanoma in situ
0.674 0.326 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.674 0.326 0.000
C60-C63 Malignant neoplasms of male genital organs
0.672 0.328 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.671 0.328 0.000
V10-V19 Pedal cyclist injured in transport accident
0.670 0.329 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.670 0.330 0.000
Z46.8 Fitting and adjustment of other specified devices
0.670 0.330 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.670 0.330 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.670 0.330 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.670 0.330 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.670 0.330 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.670 0.330 0.000
Z46.1 Fitting and adjustment of hearing aid
0.670 0.330 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.670 0.330 0.000
K56.6 Other and unspecified intestinal obstruction
0.668 0.331 0.000
R33 Retention of urine
0.668 0.332 0.000
Z36 Antenatal screening
0.668 0.332 0.000
Y44 Agents primarily affecting blood constituents
0.668 0.332 0.000
I42.0 Dilated cardiomyopathy
0.667 0.333 0.000
N37 Urethral disorders in diseases classified elsewhere
0.666 0.334 0.000
N34 Urethritis and urethral syndrome
0.666 0.334 0.000
N33 Bladder disorders in diseases classified elsewhere
0.666 0.334 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.666 0.334 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
K82.9 Disease of gallbladder, unspecified
0.665 0.335 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.664 0.336 0.000
O07 Failed attempted abortion
0.664 0.336 0.000
O06 Unspecified abortion
0.664 0.336 0.000
O05 Other abortion
0.664 0.336 0.000
O01 Hydatidiform mole
0.664 0.336 0.000
I77.1 Stricture of artery
0.663 0.337 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.663 0.337 0.000
I73.8 Other specified peripheral vascular diseases
0.663 0.337 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.663 0.337 0.000
R35 Polyuria
0.662 0.338 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.661 0.339 0.000
N75 Diseases of Bartholin's gland
0.660 0.340 0.000
K11 Diseases of salivary glands
0.660 0.340 0.000
H80-H83 Diseases of inner ear
0.659 0.341 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.658 0.342 0.000
Y89 Sequelae of other external causes
0.658 0.342 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.658 0.342 0.000
N42.9 Disorder of prostate, unspecified
0.658 0.342 0.000
Z88.2 Personal history of allergy to sulphonamides
0.656 0.344 0.000
I45.5 Other specified heart block
0.656 0.344 0.000
I07 Rheumatic tricuspid valve diseases
0.655 0.345 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.655 0.345 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.655 0.345 0.000
K65-K67 Diseases of peritoneum
0.654 0.346 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.654 0.346 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.654 0.346 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.654 0.346 0.000
K13.5 Oral submucous fibrosis
0.654 0.346 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.654 0.346 0.000
K13.3 Hairy leukoplakia
0.654 0.346 0.000
K13.1 Cheek and lip biting
0.654 0.346 0.000
N36 Other disorders of urethra
0.654 0.346 0.000
L50-L54 Urticaria and erythema
0.652 0.348 0.000
C44.2 Skin of ear and external auricular canal
0.652 0.348 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.652 0.348 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.651 0.348 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.651 0.349 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.651 0.349 0.000
I35.0 Aortic (valve) stenosis
0.651 0.349 0.000
L40-L45 Papulosquamous disorders
0.650 0.350 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.650 0.350 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.650 0.350 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.650 0.350 0.000
K85 Acute pancreatitis
0.650 0.350 0.000
Z53.9 Procedure not carried out, unspecified reason
0.649 0.351 0.000
Z94.7 Corneal transplant status
0.649 0.351 0.000
I70.0 Atherosclerosis of aorta
0.649 0.351 0.000
K60.1 Chronic anal fissure
0.649 0.351 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.648 0.351 0.000
Y43.3 Other antineoplastic drugs
0.648 0.352 0.000
N72 Inflammatory disease of cervix uteri
0.647 0.352 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.647 0.353 0.000
D80-D89 Certain disorders involving the immune mechanism
0.647 0.353 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.647 0.353 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.646 0.353 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.646 0.354 0.000
K80 Cholelithiasis
0.646 0.354 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.646 0.354 0.000
H60-H62 Diseases of external ear
0.645 0.355 0.000
Y59 Other and unspecified vaccines and biological substances
0.645 0.355 0.000
Y58 Bacterial vaccines
0.645 0.355 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.645 0.355 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.645 0.355 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.645 0.355 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.645 0.355 0.000
Y52 Agents primarily affecting the cardiovascular system
0.645 0.355 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.645 0.355 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.645 0.355 0.000
Y48 Anaesthetics and therapeutic gases
0.645 0.355 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.645 0.355 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.645 0.355 0.000
Y40 Systemic antibiotics
0.645 0.355 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.644 0.356 0.000
Z57 Occupational exposure to risk-factors
0.644 0.356 0.000
Y85 Sequelae of transport accidents
0.644 0.356 0.000
R00.0 Tachycardia, unspecified
0.644 0.356 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.643 0.357 0.000
N32.4 Rupture of bladder, nontraumatic
0.640 0.360 0.000
N32.2 Vesical fistula, not elsewhere classified
0.640 0.360 0.000
K58 Irritable bowel syndrome
0.640 0.360 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.640 0.360 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.640 0.360 0.000
I61.8 Other intracerebral haemorrhage
0.640 0.360 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.639 0.361 0.000
K81.1 Chronic cholecystitis
0.639 0.361 0.000
K01 Embedded and impacted teeth
0.638 0.361 0.000
N20-N23 Urolithiasis
0.638 0.362 0.000
D61 Other aplastic anaemias
0.638 0.362 0.000
D64 Other anaemias
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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