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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76123431
log Bayes Factor = 7.56428
Chromosome 1   position 46,357,802  (GRCh37) Explore rs76123431 on Ensembl!
Variant rs76123431 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
O60-O75 Complications of labour and delivery
0.994 0.006 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
D60-D64 Aplastic and other anaemias
0.972 0.028 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.969 0.031 0.000
D64 Other anaemias
0.966 0.034 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.965 0.035 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.963 0.037 0.000
D64.9 Anaemia, unspecified
0.961 0.039 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.961 0.039 0.000
E70-E90 Metabolic disorders
0.961 0.039 0.000
E87.6 Hypokalaemia
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.957 0.043 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.937 0.063 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.933 0.067 0.000
E87.5 Hyperkalaemia
0.923 0.077 0.000
O66 Other obstructed labour
0.923 0.077 0.000
O32.1 Maternal care for breech presentation
0.922 0.078 0.000
S40-S49 Injuries to the shoulder and upper arm
0.921 0.079 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
O73 Retained placenta and membranes, without haemorrhage
0.916 0.084 0.000
D50-D53 Nutritional anaemias
0.912 0.088 0.000
S10-S19 Injuries to the neck
0.908 0.091 0.000
O63 Long labour
0.900 0.100 0.000
M70-M79 Other soft tissue disorders
0.895 0.105 0.000
Chapter V Mental and behavioural disorders
0.894 0.106 0.000
Chapter X Diseases of the respiratory system
0.891 0.109 0.000
M05-M14 Inflammatory polyarthropathies
0.891 0.109 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.891 0.109 0.000
O41 Other disorders of amniotic fluid and membranes
0.889 0.111 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.887 0.113 0.000
D80-D89 Certain disorders involving the immune mechanism
0.884 0.116 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.883 0.117 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.882 0.118 0.000
J40-J47 Chronic lower respiratory diseases
0.880 0.120 0.000
J47 Bronchiectasis
0.872 0.128 0.000
T66-T78 Other and unspecified effects of external causes
0.871 0.129 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.870 0.130 0.000
M75 Shoulder lesions
0.865 0.135 0.000
E87.7 Fluid overload
0.865 0.135 0.000
O63.1 Prolonged second stage (of labour)
0.865 0.135 0.000
W00-W19 Falls
0.864 0.136 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.864 0.136 0.000
D51 Vitamin B12 deficiency anaemia
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
S50-S59 Injuries to the elbow and forearm
0.862 0.138 0.000
M06 Other rheumatoid arthritis
0.858 0.142 0.000
F30-F39 Mood [affective] disorders
0.858 0.142 0.000
M75.1 Rotator cuff syndrome
0.855 0.145 0.000
O40 Polyhydramnios
0.855 0.145 0.000
O36 Maternal care for other known or suspected foetal problems
0.855 0.145 0.000
M50-M54 Other dorsopathies
0.854 0.146 0.000
M20-M25 Other joint disorders
0.853 0.147 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.848 0.152 0.000
O72 Postpartum haemorrhage
0.848 0.152 0.000
M86-M90 Other osteopathies
0.846 0.154 0.000
S42 Fracture of shoulder and upper arm
0.842 0.158 0.000
M06.9 Rheumatoid arthritis, unspecified
0.840 0.160 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.830 0.170 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.826 0.174 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.825 0.175 0.000
O85-O92 Complications predominantly related to the puerperium
0.825 0.175 0.000
O73.0 Retained placenta, without haemorrhage
0.825 0.175 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.823 0.177 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.822 0.178 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.821 0.179 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.819 0.181 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.817 0.183 0.000
O44 Placenta praevia
0.817 0.183 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.816 0.184 0.000
E20-E35 Disorders of other endocrine glands
0.814 0.186 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.812 0.188 0.000
S42.2 Fracture of upper end of humerus
0.810 0.190 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.809 0.191 0.000
F32 Depressive episode
0.808 0.192 0.000
O20 Haemorrhage in early pregnancy
0.808 0.192 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.804 0.196 0.000
M80-M85 Disorders of bone density and structure
0.803 0.197 0.000
Q60-Q64 Congenital malformations of the urinary system
0.803 0.197 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.802 0.198 0.000
M15-M19 Arthrosis
0.800 0.200 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.799 0.201 0.000
J40 Bronchitis, not specified as acute or chronic
0.799 0.201 0.000
M40-M43 Deforming dorsopathies
0.799 0.201 0.000
O30 Multiple gestation
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.796 0.204 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.793 0.207 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.792 0.208 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.792 0.208 0.000
Y40 Systemic antibiotics
0.791 0.209 0.000
Chapter II Neoplasms
0.790 0.210 0.000
T00-T07 Injuries involving multiple body regions
0.788 0.212 0.000
S42.20 Fracture of upper end of humerus (closed)
0.788 0.212 0.000
M19 Other arthrosis
0.787 0.213 0.000
F31 Bipolar affective disorder
0.786 0.214 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.784 0.215 0.000
O61 Failed induction of labour
0.781 0.219 0.000
O32.8 Maternal care for other malpresentation of foetus
0.779 0.221 0.000
M34 Systemic sclerosis
0.778 0.222 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.777 0.223 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.777 0.223 0.000
W19 Unspecified fall
0.777 0.223 0.000
M00-M03 Infectious arthropathies
0.775 0.225 0.000
O48 Prolonged pregnancy
0.774 0.226 0.000
O34.3 Maternal care for cervical incompetence
0.773 0.227 0.000
M19.9 Arthrosis, unspecified
0.773 0.227 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.772 0.227 0.000
D52 Folate deficiency anaemia
0.772 0.228 0.000
V40-V49 Car occupant injured in transport accident
0.770 0.230 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.770 0.230 0.000
O36.9 Maternal care for foetal problem, unspecified
0.768 0.232 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.768 0.232 0.000
O75.0 Maternal distress during labour and delivery
0.767 0.233 0.000
Chapter VI Diseases of the nervous system
0.766 0.234 0.000
M50 Cervical disk disorders
0.766 0.234 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.763 0.237 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.762 0.238 0.000
C15-C26 Malignant neoplasms of digestive organs
0.761 0.239 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.761 0.239 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.761 0.239 0.000
S90-S99 Injuries to the ankle and foot
0.760 0.240 0.000
Chapter I Certain infectious and parasitic diseases
0.758 0.242 0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage
0.758 0.242 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.758 0.242 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.756 0.244 0.000
E10-E14 Diabetes mellitus
0.752 0.248 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.751 0.249 0.000
O20.0 Threatened abortion
0.749 0.250 0.000
J84 Other interstitial pulmonary diseases
0.749 0.251 0.000
O75.8 Other specified complications of labour and delivery
0.745 0.255 0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.742 0.258 0.000
T78 Adverse effects, not elsewhere classified
0.740 0.260 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.739 0.261 0.000
M24 Other specific joint derangements
0.739 0.261 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.738 0.262 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.737 0.263 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
E87.3 Alkalosis
0.733 0.266 0.000
O41.0 Oligohydramnios
0.733 0.267 0.000
X20-X29 Contact with venomous animals and plants
0.731 0.269 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.725 0.275 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.724 0.275 0.000
E40-E46 Malnutrition
0.724 0.276 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.723 0.277 0.000
S14 Injury of nerves and spinal cord at neck level
0.723 0.277 0.000
M05 Seropositive rheumatoid arthritis
0.722 0.278 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.721 0.279 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.720 0.280 0.000
O72.1 Other immediate postpartum haemorrhage
0.720 0.280 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.718 0.282 0.000
M19.94 Arthrosis, unspecified (Hand)
0.718 0.282 0.000
S50 Superficial injury of forearm
0.718 0.282 0.000
O24 Diabetes mellitus in pregnancy
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.717 0.283 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.716 0.284 0.000
O33 Maternal care for known or suspected disproportion
0.716 0.284 0.000
O31 Complications specific to multiple gestation
0.716 0.284 0.000
O43 Placental disorders
0.715 0.285 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.715 0.285 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.712 0.288 0.000
O71 Other obstetric trauma
0.712 0.288 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.712 0.288 0.000
O60 Preterm delivery
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
Y57 Other and unspecified drugs and medicaments
0.711 0.289 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
M84 Disorders of continuity of bone
0.710 0.290 0.000
E85 Amyloidosis
0.709 0.290 0.000
T86 Failure and rejection of transplanted organs and tissues
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
O36.6 Maternal care for excessive foetal growth
0.708 0.292 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.708 0.292 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.707 0.293 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.707 0.293 0.000
T68 Hypothermia
0.707 0.293 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.706 0.294 0.000
D61 Other aplastic anaemias
0.705 0.295 0.000
C16 Malignant neoplasm of stomach
0.705 0.295 0.000
S40 Superficial injury of shoulder and upper arm
0.705 0.295 0.000
Y40.8 Other systemic antibiotics
0.705 0.295 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.703 0.297 0.000
Q80-Q89 Other congenital malformations
0.703 0.297 0.000
W19.4 Street and highway
0.702 0.298 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.701 0.299 0.000
S51 Open wound of forearm
0.700 0.300 0.000
W18 Other fall on same level
0.700 0.300 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.699 0.301 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.699 0.301 0.000
E73 Lactose intolerance
0.698 0.302 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.697 0.303 0.000
O62 Abnormalities of forces of labour
0.696 0.304 0.000
E83 Disorders of mineral metabolism
0.696 0.304 0.000
O44.1 Placenta praevia with haemorrhage
0.696 0.304 0.000
Chapter VIII Diseases of the ear and mastoid process
0.695 0.304 0.000
M50.3 Other cervical disk degeneration
0.695 0.305 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.693 0.307 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.692 0.307 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.692 0.307 0.000
D64.8 Other specified anaemias
0.692 0.308 0.000
D64.4 Congenital dyserythropoietic anaemia
0.692 0.308 0.000
D64.3 Other sideroblastic anaemias
0.692 0.308 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.692 0.308 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.692 0.308 0.000
D64.0 Hereditary sideroblastic anaemia
0.692 0.308 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
E87.4 Mixed disorder of acid-base balance
0.691 0.309 0.000
O46.9 Antepartum haemorrhage, unspecified
0.691 0.309 0.000
D80 Immunodeficiency with predominantly antibody defects
0.690 0.310 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.690 0.310 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.690 0.310 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.689 0.311 0.000
O32.6 Maternal care for compound presentation
0.689 0.311 0.000
O32.4 Maternal care for high head at term
0.689 0.311 0.000
O32.3 Maternal care for face, brow and chin presentation
0.689 0.311 0.000
O32.2 Maternal care for transverse and oblique lie
0.689 0.311 0.000
E84 Cystic fibrosis
0.689 0.311 0.000
E79 Disorders of purine and pyrimidine metabolism
0.689 0.311 0.000
E77 Disorders of glycoprotein metabolism
0.689 0.311 0.000
E76 Disorders of glycosaminoglycan metabolism
0.689 0.311 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.689 0.311 0.000
E74 Other disorders of carbohydrate metabolism
0.689 0.311 0.000
E72 Other disorders of amino-acid metabolism
0.689 0.311 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.689 0.311 0.000
E70 Disorders of aromatic amino-acid metabolism
0.689 0.311 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.689 0.311 0.000
M34.9 Systemic sclerosis, unspecified
0.688 0.312 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
F99-F99 Unspecified mental disorder
0.687 0.313 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.686 0.314 0.000
M53 Other dorsopathies, not elsewhere classified
0.686 0.314 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.682 0.318 0.000
E28 Ovarian dysfunction
0.682 0.318 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.682 0.318 0.000
E11 Non-insulin-dependent diabetes mellitus
0.681 0.319 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.680 0.320 0.000
M25 Other joint disorders, not elsewhere classified
0.680 0.320 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.680 0.320 0.000
M21 Other acquired deformities of limbs
0.679 0.321 0.000
C25 Malignant neoplasm of pancreas
0.679 0.321 0.000
F20 Schizophrenia
0.678 0.322 0.000
C51-C58 Malignant neoplasms of female genital organs
0.678 0.322 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.677 0.323 0.000
S12 Fracture of neck
0.676 0.324 0.000
A30-A49 Other bacterial diseases
0.676 0.324 0.000
D55-D59 Haemolytic anaemias
0.676 0.324 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.673 0.327 0.000
O00-O08 Pregnancy with abortive outcome
0.673 0.327 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.672 0.328 0.000
M99 Biomechanical lesions, not elsewhere classified
0.672 0.328 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.672 0.328 0.000
D52.9 Folate deficiency anaemia, unspecified
0.672 0.328 0.000
T18 Foreign body in alimentary tract
0.671 0.329 0.000
J09-J18 Influenza and pneumonia
0.671 0.329 0.000
O86 Other puerperal infections
0.670 0.330 0.000
M89 Other disorders of bone
0.669 0.331 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.669 0.331 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.669 0.331 0.000
O34.6 Maternal care for abnormality of vagina
0.669 0.331 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.669 0.331 0.000
O34.4 Maternal care for other abnormalities of cervix
0.669 0.331 0.000
O34.0 Maternal care for congenital malformation of uterus
0.669 0.331 0.000
Q18 Other congenital malformations of face and neck
0.668 0.332 0.000
M07 Psoriatic and enteropathic arthropathies
0.668 0.332 0.000
M75.2 Bicipital tendinitis
0.668 0.332 0.000
Q61 Cystic kidney disease
0.667 0.333 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.666 0.334 0.000
M43 Other deforming dorsopathies
0.665 0.334 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
O32.0 Maternal care for unstable lie
0.664 0.335 0.000
J42 Unspecified chronic bronchitis
0.665 0.335 0.000
M19.1 Posttraumatic arthrosis of other joints
0.664 0.336 0.000
O23 Infections of genito-urinary tract in pregnancy
0.664 0.336 0.000
Q63 Other congenital malformations of kidney
0.663 0.337 0.000
O66.9 Obstructed labour, unspecified
0.662 0.338 0.000
O66.8 Other specified obstructed labour
0.662 0.338 0.000
O66.4 Failed trial of labour, unspecified
0.662 0.338 0.000
O66.3 Obstructed labour due to other abnormalities of foetus
0.662 0.338 0.000
O66.2 Obstructed labour due to unusually large foetus
0.662 0.338 0.000
O66.1 Obstructed labour due to locked twins
0.662 0.338 0.000
S48 Traumatic amputation of shoulder and upper arm
0.661 0.339 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.661 0.339 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.661 0.339 0.000
S44 Injury of nerves at shoulder and upper arm level
0.661 0.339 0.000
S41 Open wound of shoulder and upper arm
0.661 0.339 0.000
S47 Crushing injury of shoulder and upper arm
0.661 0.339 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.659 0.341 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.658 0.342 0.000
Q35-Q37 Cleft lip and cleft palate
0.658 0.342 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.658 0.342 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.658 0.342 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.657 0.343 0.000
M90 Osteopathies in diseases classified elsewhere
0.657 0.343 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.656 0.343 0.000
M14 Arthropathies in other diseases classified elsewhere
0.656 0.344 0.000
T09 Other injuries of spine and trunk, level unspecified
0.655 0.345 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
X41.9 Unspecified place
0.655 0.345 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.654 0.346 0.000
D53 Other nutritional anaemias
0.654 0.346 0.000
O30.0 Twin pregnancy
0.653 0.347 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.652 0.348 0.000
S10 Superficial injury of neck
0.652 0.348 0.000
S19 Other and unspecified injuries of neck
0.651 0.349 0.000
S17 Crushing injury of neck
0.651 0.349 0.000
S15 Injury of blood vessels at neck level
0.651 0.349 0.000
S11 Open wound of neck
0.651 0.349 0.000
S18 Traumatic amputation at neck level
0.651 0.349 0.000
S16 Injury of muscle and tendon at neck level
0.651 0.349 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.650 0.349 0.000
J80 Adult respiratory distress syndrome
0.650 0.350 0.000
M71 Other bursopathies
0.650 0.350 0.000
F80-F89 Disorders of psychological development
0.650 0.350 0.000
M88 Paget's disease of bone [osteitis deformans]
0.650 0.350 0.000
C15 Malignant neoplasm of oesophagus
0.650 0.350 0.000
O34.1 Maternal care for tumour of corpus uteri
0.649 0.351 0.000
C91 Lymphoid leukaemia
0.647 0.353 0.000
M34.8 Other forms of systemic sclerosis
0.646 0.354 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.646 0.354 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.645 0.354 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.645 0.354 0.000
E22 Hyperfunction of pituitary gland
0.645 0.355 0.000
W19.3 Sports and athletics area
0.645 0.355 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.645 0.355 0.000
E88 Other metabolic disorders
0.645 0.355 0.000
F23 Acute and transient psychotic disorders
0.645 0.355 0.000
E11.3 With ophthalmic complications
0.644 0.356 0.000
T14 Injury of unspecified body region
0.643 0.357 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.643 0.357 0.000
X60-X84 Intentional self-harm
0.643 0.357 0.000
W07 Fall involving chair
0.642 0.358 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.642 0.358 0.000
T00 Superficial injuries involving multiple body regions
0.641 0.358 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.641 0.359 0.000
F70-F79 Mental retardation
0.641 0.359 0.000
E23 Hypofunction and other disorders of pituitary gland
0.641 0.359 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.640 0.360 0.000
F31.7 Bipolar affective disorder, currently in remission
0.640 0.360 0.000
C56 Malignant neoplasm of ovary
0.639 0.361 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.639 0.361 0.000
M12 Other specific arthropathies
0.639 0.361 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.639 0.361 0.000
M08 Juvenile arthritis
0.639 0.361 0.000
O75.9 Complication of labour and delivery, unspecified
0.639 0.361 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.639 0.361 0.000
O75.4 Other complications of obstetric surgery and procedures
0.639 0.361 0.000
O75.3 Other infection during labour
0.639 0.361 0.000
O75.1 Shock during or following labour and delivery
0.639 0.361 0.000
M45-M49 Spondylopathies
0.638 0.362 0.000
C83.3 Large cell (diffuse)
0.638 0.362 0.000
T79-T79 Certain early complications of trauma
0.638 0.362 0.000
M76 Enthesopathies of lower limb, excluding foot
0.637 0.362 0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified
0.637 0.363 0.000
O41.1 Infection of amniotic sac and membranes
0.637 0.363 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.637 0.363 0.000
A41 Other septicaemia
0.637 0.363 0.000
W08 Fall involving other furniture
0.637 0.363 0.000
M95.0 Acquired deformity of nose
0.637 0.363 0.000
M70.4 Prepatellar bursitis
0.636 0.364 0.000
J43 Emphysema
0.636 0.364 0.000
Y59 Other and unspecified vaccines and biological substances
0.636 0.364 0.000
Y58 Bacterial vaccines
0.636 0.364 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.636 0.364 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.636 0.364 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.636 0.364 0.000
Y48 Anaesthetics and therapeutic gases
0.636 0.364 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.636 0.364 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.636 0.364 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.636 0.364 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.636 0.364 0.000
O90 Complications of the puerperium, not elsewhere classified
0.635 0.365 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.635 0.365 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.635 0.365 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.634 0.365 0.000
D84 Other immunodeficiencies
0.634 0.366 0.000
D83 Common variable immunodeficiency
0.634 0.366 0.000
D82 Immunodeficiency associated with other major defects
0.634 0.366 0.000
D81 Combined immunodeficiencies
0.634 0.366 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.633 0.367 0.000
O97 Death from sequelae of direct obstetric causes
0.633 0.367 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.633 0.367 0.000
O95 Obstetric death of unspecified cause
0.633 0.367 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.633 0.367 0.000
W20-W49 Exposure to inanimate mechanical forces
0.633 0.367 0.000
S72 Fracture of femur
0.632 0.368 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.632 0.368 0.000
O29 Complications of anaesthesia during pregnancy
0.632 0.368 0.000
O28 Abnormal findings on antenatal screening of mother
0.632 0.368 0.000
O22 Venous complications in pregnancy
0.632 0.368 0.000
O21 Excessive vomiting in pregnancy
0.632 0.368 0.000
O25 Malnutrition in pregnancy
0.632 0.368 0.000
U88 Agent resistant to multiple antibiotics
0.632 0.368 0.000
T13 Other injuries of lower limb, level unspecified
0.632 0.368 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.631 0.369 0.000
J41 Simple and mucopurulent chronic bronchitis
0.631 0.369 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.631 0.369 0.000
O36.5 Maternal care for poor foetal growth
0.630 0.370 0.000
O63.9 Long labour, unspecified
0.629 0.370 0.000
M75.4 Impingement syndrome of shoulder
0.629 0.371 0.000
O61.0 Failed medical induction of labour
0.629 0.371 0.000
C92 Myeloid leukaemia
0.628 0.372 0.000
M22 Disorders of patella
0.628 0.372 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.627 0.373 0.000
S52 Fracture of forearm
0.627 0.373 0.000
Q50-Q56 Congenital malformations of genital organs
0.626 0.374 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.625 0.375 0.000
T75 Effects of other external causes
0.624 0.376 0.000
T74 Maltreatment syndromes
0.624 0.376 0.000
T73 Effects of other deprivation
0.624 0.376 0.000
T70 Effects of air pressure and water pressure
0.624 0.376 0.000
T69 Other effects of reduced temperature
0.624 0.376 0.000
T67 Effects of heat and light
0.624 0.376 0.000
T71 Asphyxiation
0.624 0.376 0.000
T66 Unspecified effects of radiation
0.624 0.376 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.624 0.376 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.624 0.376 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.624 0.376 0.000
M96.5 Postradiation scoliosis
0.624 0.376 0.000
M96.4 Postsurgical lordosis
0.624 0.376 0.000
M96.3 Postlaminectomy kyphosis
0.624 0.376 0.000
M96.2 Postradiation kyphosis
0.624 0.376 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.623 0.376 0.000
T98 Sequelae of other and unspecified effects of external causes
0.623 0.377 0.000
E34 Other endocrine disorders
0.622 0.378 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.621 0.379 0.000
M50.2 Other cervical disk displacement
0.621 0.379 0.000
M75.8 Other shoulder lesions
0.620 0.379 0.000
W17 Other fall from one level to another
0.619 0.380 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.619 0.380 0.000
W15 Fall from cliff
0.619 0.380 0.000
W14 Fall from tree
0.619 0.380 0.000
W12 Fall on and from scaffolding
0.619 0.380 0.000
W11 Fall on and from ladder
0.619 0.380 0.000
W09 Fall involving playground equipment
0.619 0.380 0.000
W05 Fall involving wheelchair
0.619 0.380 0.000
W04 Fall while being carried or supported by other persons
0.619 0.380 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.619 0.380 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.619 0.380 0.000
W00 Fall on same level involving ice and snow
0.619 0.380 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.619 0.381 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.619 0.381 0.000
D51.2 Transcobalamin II deficiency
0.619 0.381 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.619 0.381 0.000
S59 Other and unspecified injuries of forearm
0.618 0.382 0.000
S58 Traumatic amputation of forearm
0.618 0.382 0.000
S57 Crushing injury of forearm
0.618 0.382 0.000
S56 Injury of muscle and tendon at forearm level
0.618 0.382 0.000
S55 Injury of blood vessels at forearm level
0.618 0.382 0.000
S54 Injury of nerves at forearm level
0.618 0.382 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.618 0.382 0.000
W10 Fall on and from stairs and steps
0.618 0.382 0.000
W51 Striking against or bumped into by another person
0.618 0.382 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.618 0.382 0.000
C16.0 Cardia
0.618 0.382 0.000
T91 Sequelae of injuries of neck and trunk
0.617 0.383 0.000
S51.0 Open wound of elbow
0.617 0.383 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.617 0.383 0.000
Q00-Q07 Congenital malformations of the nervous system
0.616 0.383 0.000
F30 Manic episode
0.616 0.384 0.000
M06.8 Other specified rheumatoid arthritis
0.615 0.385 0.000
M06.4 Inflammatory polyarthropathy
0.615 0.385 0.000
M06.3 Rheumatoid nodule
0.615 0.385 0.000
M06.2 Rheumatoid bursitis
0.615 0.385 0.000
M06.1 Adult-onset Still's disease
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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