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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76226443
log Bayes Factor = 8.8867
Chromosome 7   position 32,518,614  (GRCh37) Explore rs76226443 on Ensembl!
Variant rs76226443 is part of Cluster X0018

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.992 0.008 0.000
I26 Pulmonary embolism
0.992 0.008 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.992 0.008 0.000
J20-J22 Other acute lower respiratory infections
0.992 0.008 0.000
J22 Unspecified acute lower respiratory infection
0.991 0.009 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.983 0.017 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.980 0.020 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.975 0.025 0.000
S60-S69 Injuries to the wrist and hand
0.971 0.029 0.000
S80-S89 Injuries to the knee and lower leg
0.966 0.034 0.000
S00-S09 Injuries to the head
0.961 0.039 0.000
S61 Open wound of wrist and hand
0.960 0.040 0.000
Chapter I Certain infectious and parasitic diseases
0.959 0.041 0.000
Q21 Congenital malformations of cardiac septa
0.957 0.043 0.000
H90-H95 Other disorders of ear
0.956 0.044 0.000
E10-E14 Diabetes mellitus
0.950 0.050 0.000
Q21.1 Atrial septal defect
0.945 0.055 0.000
S82 Fracture of lower leg, including ankle
0.931 0.069 0.000
E10 Insulin-dependent diabetes mellitus
0.929 0.071 0.000
I67 Other cerebrovascular diseases
0.928 0.072 0.000
E00-E07 Disorders of thyroid gland
0.928 0.072 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.927 0.073 0.000
S61.1 Open wound of finger(s) with damage to nail
0.920 0.080 0.000
H90 Conductive and sensorineural hearing loss
0.918 0.082 0.000
Chapter VI Diseases of the nervous system
0.913 0.087 0.000
H65-H75 Diseases of middle ear and mastoid
0.911 0.089 0.000
S82.1 Fracture of upper end of tibia
0.909 0.091 0.000
S09 Other and unspecified injuries of head
0.906 0.094 0.000
T93 Sequelae of injuries of lower limb
0.898 0.102 0.000
E04 Other non-toxic goitre
0.896 0.104 0.000
S82.10 Fracture of upper end of tibia (closed)
0.894 0.106 0.000
T92 Sequelae of injuries of upper limb
0.887 0.113 0.000
G40-G47 Episodic and paroxysmal disorders
0.882 0.118 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.881 0.119 0.000
S70-S79 Injuries to the hip and thigh
0.876 0.124 0.000
J60-J70 Lung diseases due to external agents
0.875 0.125 0.000
S09.9 Unspecified injury of head
0.867 0.133 0.000
S02 Fracture of skull and facial bones
0.860 0.140 0.000
H65 Nonsuppurative otitis media
0.857 0.143 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.854 0.146 0.000
E20-E35 Disorders of other endocrine glands
0.845 0.155 0.000
G40 Epilepsy
0.844 0.156 0.000
S80 Superficial injury of lower leg
0.837 0.163 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.836 0.164 0.000
I60 Subarachnoid haemorrhage
0.832 0.168 0.000
Q50-Q56 Congenital malformations of genital organs
0.830 0.170 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.828 0.172 0.000
H90.5 Sensorineural hearing loss, unspecified
0.824 0.176 0.000
A00-A09 Intestinal infectious diseases
0.822 0.178 0.000
S40-S49 Injuries to the shoulder and upper arm
0.822 0.178 0.000
E10.4 With neurological complications
0.819 0.181 0.000
S61.8 Open wound of other parts of wrist and hand
0.818 0.182 0.000
H91 Other hearing loss
0.817 0.183 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.817 0.183 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.815 0.185 0.000
Q80-Q89 Other congenital malformations
0.815 0.185 0.000
T43.2 Other and unspecified antidepressants
0.814 0.185 0.000
H74 Other disorders of middle ear and mastoid
0.814 0.186 0.000
E10.9 Without complications
0.814 0.186 0.000
Chapter XI Diseases of the digestive system
0.814 0.186 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.811 0.189 0.000
T90 Sequelae of injuries of head
0.811 0.189 0.000
J00-J06 Acute upper respiratory infections
0.808 0.192 0.000
A30-A49 Other bacterial diseases
0.804 0.196 0.000
I67.9 Cerebrovascular disease, unspecified
0.797 0.203 0.000
I67.8 Other specified cerebrovascular diseases
0.797 0.203 0.000
Chapter XX External causes of morbidity and mortality
0.797 0.203 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
I05-I09 Chronic rheumatic heart diseases
0.794 0.206 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.794 0.206 0.000
S06 Intracranial injury
0.794 0.206 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.791 0.209 0.000
E04.9 Non-toxic goitre, unspecified
0.791 0.209 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.789 0.211 0.000
I69 Sequelae of cerebrovascular disease
0.789 0.211 0.000
S64 Injury of nerves at wrist and hand level
0.788 0.212 0.000
I67.1 Cerebral aneurysm, nonruptured
0.788 0.212 0.000
S62 Fracture at wrist and hand level
0.785 0.215 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
E04.1 Non-toxic single thyroid nodule
0.784 0.216 0.000
I62 Other nontraumatic intracranial haemorrhage
0.782 0.218 0.000
I61 Intracerebral haemorrhage
0.781 0.219 0.000
K90-K93 Other diseases of the digestive system
0.781 0.219 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.779 0.221 0.000
A04 Other bacterial intestinal infections
0.777 0.223 0.000
S72 Fracture of femur
0.777 0.223 0.000
T42.4 Benzodiazepines
0.774 0.226 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.772 0.228 0.000
Q23 Congenital malformations of aortic and mitral valves
0.772 0.228 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.771 0.229 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.768 0.232 0.000
J95-J99 Other diseases of the respiratory system
0.768 0.232 0.000
E40-E46 Malnutrition
0.767 0.233 0.000
S82.6 Fracture of lateral malleolus
0.765 0.235 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.765 0.235 0.000
G40.9 Epilepsy, unspecified
0.762 0.238 0.000
B25-B34 Other viral diseases
0.761 0.239 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.757 0.243 0.000
B50-B64 Protozoal diseases
0.755 0.245 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
H71 Cholesteatoma of middle ear
0.752 0.248 0.000
S80.9 Superficial injury of lower leg, unspecified
0.752 0.248 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.751 0.249 0.000
S02.0 Fracture of vault of skull
0.750 0.250 0.000
E10.5 With peripheral circulatory complications
0.750 0.250 0.000
H65.3 Chronic mucoid otitis media
0.750 0.250 0.000
E10.3 With ophthalmic complications
0.749 0.251 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.748 0.252 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.746 0.254 0.000
K01 Embedded and impacted teeth
0.745 0.255 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.744 0.256 0.000
K11 Diseases of salivary glands
0.743 0.257 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.742 0.258 0.000
H90.2 Conductive hearing loss, unspecified
0.740 0.260 0.000
T91 Sequelae of injuries of neck and trunk
0.738 0.262 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.738 0.262 0.000
A49 Bacterial infection of unspecified site
0.738 0.262 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.735 0.265 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.731 0.269 0.000
E10.8 With unspecified complications
0.729 0.271 0.000
T93.2 Sequelae of other fractures of lower limb
0.729 0.271 0.000
E10.2 With renal complications
0.728 0.272 0.000
S05 Injury of eye and orbit
0.727 0.273 0.000
E04.2 Non-toxic multinodular goitre
0.727 0.273 0.000
H93 Other disorders of ear, not elsewhere classified
0.727 0.273 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.724 0.276 0.000
Q24 Other congenital malformations of heart
0.724 0.276 0.000
S71 Open wound of hip and thigh
0.722 0.278 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.721 0.279 0.000
Chapter XXII Codes for special purposes
0.720 0.279 0.000
A80-A89 Viral infections of the central nervous system
0.720 0.280 0.000
H65.0 Acute serous otitis media
0.720 0.280 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.719 0.281 0.000
E20 Hypoparathyroidism
0.719 0.281 0.000
H91.9 Hearing loss, unspecified
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Q27 Other congenital malformations of peripheral vascular system
0.716 0.284 0.000
S82.4 Fracture of fibula alone
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
E04.0 Non-toxic diffuse goitre
0.715 0.285 0.000
T17 Foreign body in respiratory tract
0.713 0.286 0.000
I28 Other diseases of pulmonary vessels
0.713 0.287 0.000
T51 Toxic effect of alcohol
0.713 0.287 0.000
K01.1 Impacted teeth
0.713 0.287 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.288 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.711 0.289 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.711 0.289 0.000
Q35-Q37 Cleft lip and cleft palate
0.711 0.289 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.711 0.289 0.000
J21 Acute bronchiolitis
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.710 0.290 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.709 0.291 0.000
H65.2 Chronic serous otitis media
0.709 0.291 0.000
E06 Thyroiditis
0.709 0.291 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.708 0.292 0.000
I77 Other disorders of arteries and arterioles
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
J69 Pneumonitis due to solids and liquids
0.706 0.294 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.706 0.294 0.000
S00 Superficial injury of head
0.705 0.295 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.704 0.296 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.704 0.296 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
E13 Other specified diabetes mellitus
0.703 0.297 0.000
T98 Sequelae of other and unspecified effects of external causes
0.702 0.297 0.000
T95 Sequelae of burns, corrosions and frostbite
0.702 0.297 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.702 0.297 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.702 0.297 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.702 0.297 0.000
S10-S19 Injuries to the neck
0.702 0.298 0.000
K05 Gingivitis and periodontal diseases
0.701 0.299 0.000
B65-B83 Helminthiases
0.700 0.299 0.000
S81 Open wound of lower leg
0.700 0.300 0.000
Q26 Congenital malformations of great veins
0.699 0.301 0.000
Q25 Congenital malformations of great arteries
0.699 0.301 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.699 0.301 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.699 0.301 0.000
I72 Other aneurysm
0.698 0.302 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.698 0.302 0.000
E07 Other disorders of thyroid
0.697 0.303 0.000
S65 Injury of blood vessels at wrist and hand level
0.696 0.304 0.000
G41 Status epilepticus
0.696 0.304 0.000
T39.1 4-Aminophenol derivatives
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
E16 Other disorders of pancreatic internal secretion
0.694 0.306 0.000
A04.5 Campylobacter enteritis
0.694 0.306 0.000
T92.0 Sequelae of open wound of upper limb
0.693 0.307 0.000
S88 Traumatic amputation of lower leg
0.692 0.308 0.000
S87 Crushing injury of lower leg
0.692 0.308 0.000
S85 Injury of blood vessels at lower leg level
0.692 0.308 0.000
S84 Injury of nerves at lower leg level
0.692 0.308 0.000
J03 Acute tonsillitis
0.692 0.308 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.691 0.309 0.000
T90.4 Sequelae of injury of eye and orbit
0.691 0.309 0.000
Q21.0 Ventricular septal defect
0.690 0.310 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.689 0.311 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.689 0.311 0.000
S08 Traumatic amputation of part of head
0.689 0.311 0.000
S07 Crushing injury of head
0.689 0.311 0.000
S04 Injury of cranial nerves
0.689 0.311 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.689 0.311 0.000
B15-B19 Viral hepatitis
0.688 0.312 0.000
B99-B99 Other infectious diseases
0.687 0.312 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.312 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.312 0.000
A75-A79 Rickettsioses
0.687 0.312 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.312 0.000
A65-A69 Other spirochaetal diseases
0.687 0.312 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.312 0.000
A15-A19 Tuberculosis
0.687 0.312 0.000
S72.4 Fracture of lower end of femur
0.687 0.313 0.000
S02.7 Multiple fractures involving skull and facial bones
0.687 0.313 0.000
S89 Other and unspecified injuries of lower leg
0.686 0.313 0.000
G40.8 Other epilepsy
0.686 0.313 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.686 0.314 0.000
Q21.8 Other congenital malformations of cardiac septa
0.686 0.314 0.000
Q21.4 Aortopulmonary septal defect
0.686 0.314 0.000
Q21.3 Tetralogy of Fallot
0.686 0.314 0.000
Q21.2 Atrioventricular septal defect
0.686 0.314 0.000
G45.4 Transient global amnesia
0.686 0.314 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.685 0.315 0.000
H70 Mastoiditis and related conditions
0.685 0.315 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.685 0.315 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.685 0.315 0.000
K91.3 Postoperative intestinal obstruction
0.685 0.315 0.000
S86 Injury of muscle and tendon at lower leg level
0.684 0.316 0.000
I60.8 Other subarachnoid haemorrhage
0.684 0.316 0.000
K09 Cysts of oral region, not elsewhere classified
0.683 0.317 0.000
T93.0 Sequelae of open wound of lower limb
0.682 0.317 0.000
E12 Malnutrition-related diabetes mellitus
0.681 0.318 0.000
E23 Hypofunction and other disorders of pituitary gland
0.681 0.319 0.000
S02.1 Fracture of base of skull
0.681 0.319 0.000
S82.2 Fracture of shaft of tibia
0.681 0.319 0.000
Q54 Hypospadias
0.681 0.319 0.000
Q60-Q64 Congenital malformations of the urinary system
0.681 0.319 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.679 0.321 0.000
S61.7 Multiple open wounds of wrist and hand
0.677 0.323 0.000
I08 Multiple valve diseases
0.677 0.323 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.677 0.323 0.000
J90-J94 Other diseases of pleura
0.676 0.324 0.000
J04 Acute laryngitis and tracheitis
0.676 0.324 0.000
E50-E64 Other nutritional deficiencies
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.673 0.327 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.672 0.328 0.000
S02.00 Fracture of vault of skull (closed)
0.671 0.329 0.000
Q51 Congenital malformations of uterus and cervix
0.670 0.330 0.000
S40 Superficial injury of shoulder and upper arm
0.670 0.330 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.670 0.330 0.000
S41 Open wound of shoulder and upper arm
0.669 0.331 0.000
S82.9 Fracture of lower leg, part unspecified
0.668 0.332 0.000
S82.7 Multiple fractures of lower leg
0.668 0.332 0.000
G81 Hemiplegia
0.668 0.332 0.000
S69 Other and unspecified injuries of wrist and hand
0.667 0.333 0.000
Q82 Other congenital malformations of skin
0.666 0.334 0.000
E10.7 With multiple complications
0.666 0.334 0.000
E10.6 With other specified complications
0.666 0.334 0.000
E10.0 With coma
0.666 0.334 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.666 0.334 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.665 0.334 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.665 0.334 0.000
I67.5 Moyamoya disease
0.665 0.334 0.000
I67.4 Hypertensive encephalopathy
0.665 0.334 0.000
I67.3 Progressive vascular leukoencephalopathy
0.665 0.334 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.665 0.334 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.665 0.335 0.000
E00 Congenital iodine-deficiency syndrome
0.665 0.335 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.335 0.000
T66-T78 Other and unspecified effects of external causes
0.665 0.335 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.664 0.336 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.663 0.337 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.663 0.337 0.000
Q28 Other congenital malformations of circulatory system
0.662 0.338 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.662 0.338 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.661 0.339 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.661 0.339 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.661 0.339 0.000
E27 Other disorders of adrenal gland
0.660 0.340 0.000
A04.8 Other specified bacterial intestinal infections
0.659 0.341 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.658 0.342 0.000
H90.0 Conductive hearing loss, bilateral
0.658 0.342 0.000
T79-T79 Certain early complications of trauma
0.656 0.344 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.656 0.344 0.000
K50-K52 Noninfective enteritis and colitis
0.655 0.345 0.000
J20 Acute bronchitis
0.654 0.346 0.000
S82.3 Fracture of lower end of tibia
0.654 0.346 0.000
S62.6 Fracture of other finger
0.653 0.347 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.653 0.347 0.000
H68 Eustachian salpingitis and obstruction
0.653 0.347 0.000
H67 Otitis media in diseases classified elsewhere
0.653 0.347 0.000
S06.5 Traumatic subdural haemorrhage
0.653 0.347 0.000
S60 Superficial injury of wrist and hand
0.652 0.348 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.652 0.348 0.000
S82.11 Fracture of upper end of tibia (open)
0.652 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
S09.8 Other specified injuries of head
0.650 0.350 0.000
S09.7 Multiple injuries of head
0.650 0.350 0.000
S09.2 Traumatic rupture of ear drum
0.650 0.350 0.000
S09.1 Injury of muscle and tendon of head
0.650 0.350 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.650 0.350 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.649 0.351 0.000
G43 Migraine
0.648 0.352 0.000
S64.1 Injury of median nerve at wrist and hand level
0.648 0.352 0.000
K92 Other diseases of digestive system
0.648 0.352 0.000
E26 Hyperaldosteronism
0.647 0.353 0.000
Y85 Sequelae of transport accidents
0.647 0.353 0.000
S82.60 Fracture of lateral malleolus (closed)
0.646 0.354 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.646 0.354 0.000
A40 Streptococcal septicaemia
0.646 0.354 0.000
I30-I52 Other forms of heart disease
0.645 0.355 0.000
E14 Unspecified diabetes mellitus
0.645 0.355 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.644 0.355 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.644 0.356 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.644 0.356 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.644 0.356 0.000
T93.1 Sequelae of fracture of femur
0.644 0.356 0.000
E04.8 Other specified non-toxic goitre
0.643 0.357 0.000
H80-H83 Diseases of inner ear
0.641 0.359 0.000
T21 Burn and corrosion of trunk
0.641 0.359 0.000
T17.2 Foreign body in pharynx
0.641 0.359 0.000
S50-S59 Injuries to the elbow and forearm
0.639 0.361 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.638 0.361 0.000
G40.5 Special epileptic syndromes
0.637 0.363 0.000
T92.1 Sequelae of fracture of arm
0.637 0.363 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.636 0.364 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.636 0.364 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.635 0.365 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.634 0.366 0.000
V80-V89 Other land transport accidents
0.634 0.366 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.633 0.367 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.632 0.368 0.000
T43.9 Psychotropic drug, unspecified
0.632 0.368 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
T43.6 Psychostimulants with abuse potential
0.632 0.368 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.632 0.368 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.632 0.368 0.000
B00 Herpesviral [herpes simplex] infections
0.632 0.368 0.000
H92 Otalgia and effusion of ear
0.631 0.369 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.631 0.369 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.631 0.369 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.630 0.370 0.000
G82 Paraplegia and tetraplegia
0.630 0.370 0.000
S02.3 Fracture of orbital floor
0.629 0.370 0.000
B95-B98 Bacterial, viral and other infectious agents
0.630 0.370 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.629 0.370 0.000
X60-X84 Intentional self-harm
0.629 0.371 0.000
S06.4 Epidural haemorrhage
0.629 0.371 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.629 0.371 0.000
S78 Traumatic amputation of hip and thigh
0.628 0.372 0.000
S77 Crushing injury of hip and thigh
0.628 0.372 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.628 0.372 0.000
S75 Injury of blood vessels at hip and thigh level
0.628 0.372 0.000
S74 Injury of nerves at hip and thigh level
0.628 0.372 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.628 0.372 0.000
E20.9 Hypoparathyroidism, unspecified
0.628 0.372 0.000
B02 Zoster [herpes zoster]
0.628 0.372 0.000
Q89 Other congenital malformations, not elsewhere classified
0.628 0.372 0.000
S82.0 Fracture of patella
0.628 0.372 0.000
J70 Respiratory conditions due to other external agents
0.627 0.373 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.627 0.373 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.627 0.373 0.000
J66 Airway disease due to specific organic dust
0.627 0.373 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.627 0.373 0.000
J62 Pneumoconiosis due to dust containing silica
0.627 0.373 0.000
J65 Pneumoconiosis associated with tuberculosis
0.627 0.373 0.000
J64 Unspecified pneumoconiosis
0.627 0.373 0.000
J60 Coalworker's pneumoconiosis
0.627 0.373 0.000
X50-X57 Overexertion, travel and privation
0.627 0.373 0.000
J95.8 Other postprocedural respiratory disorders
0.627 0.373 0.000
I42 Cardiomyopathy
0.627 0.373 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.627 0.373 0.000
H93.9 Disorder of ear, unspecified
0.627 0.373 0.000
Q23.1 Congenital insufficiency of aortic valve
0.626 0.373 0.000
K51 Ulcerative colitis
0.626 0.374 0.000
K11.8 Other diseases of salivary glands
0.626 0.374 0.000
S67 Crushing injury of wrist and hand
0.625 0.374 0.000
K05.3 Chronic periodontitis
0.625 0.375 0.000
E11 Non-insulin-dependent diabetes mellitus
0.625 0.375 0.000
S90 Superficial injury of ankle and foot
0.625 0.375 0.000
W50-W64 Exposure to animate mechanical forces
0.625 0.375 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.624 0.376 0.000
S72.40 Fracture of lower end of femur (closed)
0.623 0.377 0.000
T90.5 Sequelae of intracranial injury
0.622 0.378 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.622 0.378 0.000
K91.4 Colostomy and enterostomy malfunction
0.622 0.378 0.000
E10.1 With ketoacidosis
0.621 0.379 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.620 0.380 0.000
I74 Arterial embolism and thrombosis
0.620 0.380 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.620 0.380 0.000
K04 Diseases of pulp and periapical tissues
0.620 0.380 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.620 0.380 0.000
B34 Viral infection of unspecified site
0.619 0.381 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.617 0.383 0.000
H74.4 Polyp of middle ear
0.616 0.384 0.000
I09 Other rheumatic heart diseases
0.616 0.384 0.000
I77.1 Stricture of artery
0.615 0.385 0.000
S70 Superficial injury of hip and thigh
0.615 0.385 0.000
H65.1 Other acute nonsuppurative otitis media
0.614 0.385 0.000
G44 Other headache syndromes
0.615 0.385 0.000
S72.1 Pertrochanteric fracture
0.614 0.386 0.000
H73 Other disorders of tympanic membrane
0.614 0.386 0.000
S02.2 Fracture of nasal bones
0.614 0.386 0.000
T63 Toxic effect of contact with venomous animals
0.613 0.387 0.000
K83 Other diseases of biliary tract
0.613 0.387 0.000
S82.5 Fracture of medial malleolus
0.613 0.387 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.612 0.387 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.612 0.387 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.612 0.387 0.000
T42.3 Barbiturates
0.612 0.387 0.000
T42.2 Succinimides and oxazolidinediones
0.612 0.387 0.000
T42.1 Iminostilbenes
0.612 0.387 0.000
T42.0 Hydantoin derivatives
0.612 0.387 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.612 0.388 0.000
S02.4 Fracture of malar and maxillary bones
0.612 0.388 0.000
S71.1 Open wound of thigh
0.611 0.389 0.000
Y00-Y09 Assault
0.610 0.390 0.000
B59 Pneumocystosis
0.609 0.390 0.000
A49.0 Staphylococcal infection, unspecified
0.609 0.391 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.609 0.391 0.000
E46 Unspecified protein-energy malnutrition
0.608 0.392 0.000
J03.9 Acute tonsillitis, unspecified
0.608 0.392 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.607 0.392 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.607 0.393 0.000
E16.2 Hypoglycaemia, unspecified
0.606 0.394 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.606 0.394 0.000
E34 Other endocrine disorders
0.606 0.394 0.000
E32 Diseases of thymus
0.606 0.394 0.000
E31 Polyglandular dysfunction
0.606 0.394 0.000
E30 Disorders of puberty, not elsewhere classified
0.606 0.394 0.000
E25 Adrenogenital disorders
0.606 0.394 0.000
E24 Cushing's syndrome
0.606 0.394 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.605 0.395 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.605 0.395 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.605 0.395 0.000
J09-J18 Influenza and pneumonia
0.605 0.395 0.000
S72.2 Subtrochanteric fracture
0.604 0.396 0.000
G30-G32 Other degenerative diseases of the nervous system
0.604 0.396 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.604 0.396 0.000
A49.9 Bacterial infection, unspecified
0.603 0.397 0.000
A49.1 Streptococcal infection, unspecified
0.602 0.398 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.601 0.398 0.000
S80.7 Multiple superficial injuries of lower leg
0.600 0.400 0.000
X20-X29 Contact with venomous animals and plants
0.600 0.400 0.000
S62.5 Fracture of thumb
0.600 0.400 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.599 0.401 0.000
T65 Toxic effect of other and unspecified substances
0.599 0.401 0.000
T62 Toxic effect of other noxious substances eaten as food
0.599 0.401 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.599 0.401 0.000
T60 Toxic effect of pesticides
0.599 0.401 0.000
T57 Toxic effect of other inorganic substances
0.599 0.401 0.000
T56 Toxic effect of metals
0.599 0.401 0.000
T54 Toxic effect of corrosive substances
0.599 0.401 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.599 0.401 0.000
T52 Toxic effect of organic solvents
0.599 0.401 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.599 0.401 0.000
T58 Toxic effect of carbon monoxide
0.599 0.401 0.000
T55 Toxic effect of soaps and detergents
0.599 0.401 0.000
I42.2 Other hypertrophic cardiomyopathy
0.599 0.401 0.000
K11.2 Sialoadenitis
0.599 0.401 0.000
Y85.0 Sequelae of motor-vehicle accident
0.598 0.402 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.598 0.402 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.597 0.403 0.000
T11 Other injuries of upper limb, level unspecified
0.597 0.403 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.597 0.403 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.597 0.403 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.597 0.403 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.597 0.403 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.597 0.403 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.596 0.404 0.000
T59 Toxic effect of other gases, fumes and vapours
0.596 0.404 0.000
I70 Atherosclerosis
0.595 0.405 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.595 0.405 0.000
Q55 Other congenital malformations of male genital organs
0.595 0.405 0.000
Q53 Undescended testicle
0.595 0.405 0.000
Q52 Other congenital malformations of female genitalia
0.595 0.405 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.594 0.405 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.594 0.406 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.594 0.406 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.594 0.406 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.594 0.406 0.000
T39.4 Antirheumatics, not elsewhere classified
0.594 0.406 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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