TreeWAS – Variant ID: rs7644516

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O48 Prolonged pregnancy	0.165	0.835	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.155	0.845	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.150	0.850	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.145	0.855	0.000
O32.1 Maternal care for breech presentation	0.139	0.861	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.130	0.870	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.125	0.875	0.000
O32.4 Maternal care for high head at term	0.124	0.876	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.123	0.877	0.000
O47 False labour	0.120	0.880	0.000
O44 Placenta praevia	0.120	0.880	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.119	0.881	0.000
O32.0 Maternal care for unstable lie	0.119	0.881	0.000
O33 Maternal care for known or suspected disproportion	0.118	0.882	0.000
O46.9 Antepartum haemorrhage, unspecified	0.117	0.883	0.000
O32.2 Maternal care for transverse and oblique lie	0.115	0.885	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.112	0.888	0.000
O32.8 Maternal care for other malpresentation of foetus	0.110	0.890	0.000
O30 Multiple gestation	0.110	0.890	0.000
O42 Premature rupture of membranes	0.110	0.890	0.000
O32.6 Maternal care for compound presentation	0.108	0.892	0.000
O31 Complications specific to multiple gestation	0.106	0.894	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.105	0.895	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.105	0.895	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.104	0.896	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.104	0.896	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.104	0.896	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.104	0.896	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.104	0.896	0.000
O32.3 Maternal care for face, brow and chin presentation	0.103	0.897	0.000
O40 Polyhydramnios	0.101	0.899	0.000
O45 Premature separation of placenta [abruptio placentae]	0.100	0.900	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.100	0.900	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.099	0.901	0.000
O36 Maternal care for other known or suspected foetal problems	0.099	0.901	0.000
O43 Placental disorders	0.097	0.903	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.095	0.905	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.093	0.907	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.092	0.908	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.091	0.909	0.000
O33.9 Maternal care for disproportion, unspecified	0.090	0.910	0.000
O42.9 Premature rupture of membranes, unspecified	0.089	0.911	0.000
O44.1 Placenta praevia with haemorrhage	0.089	0.911	0.000
O47.9 False labour, unspecified	0.089	0.911	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.088	0.912	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.087	0.913	0.000
O41 Other disorders of amniotic fluid and membranes	0.086	0.914	0.000
O47.0 False labour before 37 completed weeks of gestation	0.085	0.915	0.000
O33.8 Maternal care for disproportion of other origin	0.085	0.915	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.085	0.915	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.085	0.915	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.085	0.915	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.085	0.915	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.085	0.915	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.085	0.915	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.085	0.915	0.000
O36.9 Maternal care for foetal problem, unspecified	0.085	0.915	0.000
O34.0 Maternal care for congenital malformation of uterus	0.083	0.917	0.000
O30.0 Twin pregnancy	0.082	0.918	0.000
O36.5 Maternal care for poor foetal growth	0.081	0.918	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.080	0.920	0.000
O30.9 Multiple gestation, unspecified	0.079	0.921	0.000
O30.8 Other multiple gestation	0.079	0.921	0.000
O30.2 Quadruplet pregnancy	0.079	0.921	0.000
O46.8 Other antepartum haemorrhage	0.078	0.921	0.000
O31.8 Other complications specific to multiple gestation	0.078	0.922	0.000
O34.3 Maternal care for cervical incompetence	0.078	0.922	0.000
O34.6 Maternal care for abnormality of vagina	0.077	0.922	0.000
O31.0 Papyraceous foetus	0.076	0.924	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.076	0.924	0.000
S01.0 Open wound of scalp	0.076	0.924	0.000
O30.1 Triplet pregnancy	0.075	0.924	0.000
O36.6 Maternal care for excessive foetal growth	0.075	0.925	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.074	0.926	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.074	0.926	0.000
S01 Open wound of head	0.072	0.928	0.000
O45.8 Other premature separation of placenta	0.072	0.928	0.000
O45.0 Premature separation of placenta with coagulation defect	0.072	0.928	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.072	0.928	0.000
O36.2 Maternal care for hydrops foetalis	0.071	0.929	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.071	0.929	0.000
O36.1 Maternal care for other isoimmunisation	0.071	0.929	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.070	0.930	0.000
O43.2 Morbidly adherent placenta	0.070	0.930	0.000
O43.1 Malformation of placenta	0.070	0.930	0.000
O36.4 Maternal care for intra-uterine death	0.070	0.930	0.000
O43.9 Placental disorder, unspecified	0.068	0.932	0.000
S01.5 Open wound of lip and oral cavity	0.068	0.932	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.067	0.933	0.000
O43.0 Placental transfusion syndromes	0.067	0.933	0.000
S00-S09 Injuries to the head	0.066	0.934	0.000
S01.1 Open wound of eyelid and periocular area	0.066	0.934	0.000
O34.4 Maternal care for other abnormalities of cervix	0.064	0.936	0.000
O43.8 Other placental disorders	0.061	0.939	0.000
O45.9 Premature separation of placenta, unspecified	0.061	0.939	0.000
O41.0 Oligohydramnios	0.061	0.939	0.000
O41.1 Infection of amniotic sac and membranes	0.060	0.939	0.000
S06 Intracranial injury	0.058	0.942	0.000
S00 Superficial injury of head	0.058	0.942	0.000
S01.2 Open wound of nose	0.057	0.943	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.057	0.943	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.056	0.943	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.056	0.943	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.055	0.945	0.000
S05 Injury of eye and orbit	0.052	0.947	0.000
S02 Fracture of skull and facial bones	0.052	0.948	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.051	0.949	0.000
S01.4 Open wound of cheek and temporomandibular area	0.049	0.951	0.000
S01.7 Multiple open wounds of head	0.049	0.951	0.000
S08 Traumatic amputation of part of head	0.049	0.951	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.048	0.951	0.000
S04 Injury of cranial nerves	0.048	0.952	0.000
S07 Crushing injury of head	0.048	0.952	0.000
S09 Other and unspecified injuries of head	0.048	0.952	0.000
S06.5 Traumatic subdural haemorrhage	0.048	0.952	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.047	0.953	0.000
S03.2 Dislocation of tooth	0.046	0.953	0.000
S01.8 Open wound of other parts of head	0.046	0.954	0.000
S00.9 Superficial injury of head, part unspecified	0.046	0.954	0.000
S02.0 Fracture of vault of skull	0.045	0.955	0.000
S06.2 Diffuse brain injury	0.045	0.955	0.000
S06.4 Epidural haemorrhage	0.045	0.955	0.000
S02.5 Fracture of tooth	0.044	0.956	0.000
S06.3 Focal brain injury	0.044	0.956	0.000
S09.8 Other specified injuries of head	0.044	0.956	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.044	0.956	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.044	0.956	0.000
S05.1 Contusion of eyeball and orbital tissues	0.044	0.956	0.000
S00.7 Multiple superficial injuries of head	0.043	0.957	0.000
S00.4 Superficial injury of ear	0.042	0.958	0.000
S00.0 Superficial injury of scalp	0.042	0.958	0.000
S06.1 Traumatic cerebral oedema	0.042	0.958	0.000
S00.5 Superficial injury of lip and oral cavity	0.042	0.958	0.000
S06.7 Intracranial injury with prolonged coma	0.042	0.958	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.958	0.042
S00.8 Superficial injury of other parts of head	0.042	0.958	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.041	0.959	0.000
S03.0 Dislocation of jaw	0.041	0.959	0.000
S02.00 Fracture of vault of skull (closed)	0.041	0.959	0.000
S06.8 Other intracranial injuries	0.041	0.959	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.040	0.960	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.040	0.960	0.000
S03.4 Sprain and strain of jaw	0.040	0.960	0.000
S03.3 Dislocation of other and unspecified parts of head	0.040	0.960	0.000
S03.1 Dislocation of septal cartilage of nose	0.040	0.960	0.000
S02.2 Fracture of nasal bones	0.040	0.960	0.000
S00.3 Superficial injury of nose	0.040	0.960	0.000
S02.1 Fracture of base of skull	0.039	0.961	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.039	0.961	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.039	0.961	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.039	0.961	0.000
S06.0 Concussion	0.039	0.961	0.000
S02.50 Fracture of tooth (closed)	0.038	0.962	0.000
S02.8 Fractures of other skull and facial bones	0.038	0.962	0.000
S06.9 Intracranial injury, unspecified	0.038	0.962	0.000
S05.7 Avulsion of eye	0.038	0.962	0.000
O36.8 Maternal care for other specified foetal problems	0.037	0.963	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.037	0.963	0.000
S09.2 Traumatic rupture of ear drum	0.036	0.964	0.000
O34.1 Maternal care for tumour of corpus uteri	0.036	0.964	0.001
S08.1 Traumatic amputation of ear	0.036	0.964	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.036	0.964	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.035	0.964	0.000
S02.7 Multiple fractures involving skull and facial bones	0.035	0.964	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.035	0.965	0.000
S04.5 Injury of facial nerve	0.035	0.965	0.000
S08.9 Traumatic amputation of unspecified part of head	0.035	0.965	0.000
S08.8 Traumatic amputation of other parts of head	0.035	0.965	0.000
S08.0 Avulsion of scalp	0.035	0.965	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.035	0.965	0.000
S04.9 Injury of unspecified cranial nerve	0.035	0.965	0.000
S04.8 Injury of other cranial nerves	0.035	0.965	0.000
S04.7 Injury of accessory nerve	0.035	0.965	0.000
S04.6 Injury of acoustic nerve	0.035	0.965	0.000
S04.4 Injury of abducent nerve	0.035	0.965	0.000
S04.3 Injury of trigeminal nerve	0.035	0.965	0.000
S04.2 Injury of trochlear nerve	0.035	0.965	0.000
S04.1 Injury of oculomotor nerve	0.035	0.965	0.000
S04.0 Injury of optic nerve and pathways	0.035	0.965	0.000
S07.9 Crushing injury of head, part unspecified	0.034	0.965	0.000
S07.8 Crushing injury of other parts of head	0.034	0.965	0.000
S07.1 Crushing injury of skull	0.034	0.965	0.000
S07.0 Crushing injury of face	0.034	0.965	0.000
S09.1 Injury of muscle and tendon of head	0.034	0.965	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.034	0.966	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.034	0.966	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.034	0.966	0.000
S01.3 Open wound of ear	0.033	0.967	0.000
S00.1 Contusion of eyelid and periocular area	0.033	0.967	0.000
S09.7 Multiple injuries of head	0.032	0.968	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.032	0.968	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.032	0.968	0.000
S02.3 Fracture of orbital floor	0.032	0.968	0.000
S02.51 Fracture of tooth (open)	0.032	0.968	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.032	0.968	0.000
S02.6 Fracture of mandible	0.032	0.968	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.031	0.968	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.031	0.969	0.000
S02.01 Fracture of vault of skull (open)	0.031	0.969	0.000
I12 Hypertensive renal disease	0.000	0.969	0.031
S02.20 Fracture of nasal bones (closed)	0.031	0.969	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.030	0.969	0.000
S05.8 Other injuries of eye and orbit	0.030	0.970	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.030	0.970	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.030	0.970	0.000
S02.4 Fracture of malar and maxillary bones	0.030	0.970	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.030	0.970	0.000
S02.10 Fracture of base of skull (closed)	0.029	0.971	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.029	0.971	0.000
S02.11 Fracture of base of skull (open)	0.029	0.971	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.029	0.971	0.000
S02.21 Fracture of nasal bones (open)	0.029	0.971	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.971	0.029
S05.9 Injury of eye and orbit, part unspecified	0.028	0.971	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.028	0.972	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.028	0.972	0.000
S06.01 Concussion (with open intracranial wound)	0.028	0.972	0.000
S02.81 Fractures of other skull and facial bones (open)	0.028	0.972	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.027	0.972	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.974	0.026
S02.71 Multiple fractures involving skull and facial bones (open)	0.026	0.974	0.000
S06.00 Concussion (without open intracranial wound)	0.025	0.975	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.023	0.976	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.023	0.977	0.000
S02.31 Fracture of orbital floor (open)	0.023	0.977	0.000
S02.61 Fracture of mandible (open)	0.023	0.977	0.000
S01.9 Open wound of head, part unspecified	0.021	0.979	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.021	0.979	0.000
S02.30 Fracture of orbital floor (closed)	0.017	0.982	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.983	0.017
S02.60 Fracture of mandible (closed)	0.017	0.983	0.000
Y84.1 Kidney dialysis	0.000	0.983	0.017
Y84.8 Other medical procedures	0.000	0.985	0.015
S02.40 Fracture of malar and maxillary bones (closed)	0.014	0.986	0.000
Y84.9 Medical procedure, unspecified	0.000	0.986	0.014
S09.9 Unspecified injury of head	0.013	0.987	0.000
Y84.5 Insertion of gastric or duodenal sound	0.000	0.987	0.013
Y84.3 Shock therapy	0.000	0.987	0.013
Y84.7 Blood-sampling	0.000	0.987	0.012
C44.6 Skin of upper limb, including shoulder	0.012	0.988	0.000
Y84.4 Aspiration of fluid	0.000	0.990	0.010
Y84.6 Urinary catheterisation	0.000	0.991	0.009
Y84.0 Cardiac catheterisation	0.000	0.991	0.009
Y44.2 Anticoagulants	0.000	0.993	0.007
N50.8 Other specified disorders of male genital organs	0.000	0.993	0.007
M50.2 Other cervical disk displacement	0.000	0.994	0.006
Q63.0 Accessory kidney	0.000	0.994	0.006
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.994	0.006
L40.5 Arthropathic psoriasis	0.000	0.994	0.006
M50.3 Other cervical disk degeneration	0.000	0.995	0.005
S27 Injury of other and unspecified intrathoracic organs	0.005	0.995	0.000
S20 Superficial injury of thorax	0.005	0.995	0.000
S20-S29 Injuries to the thorax	0.005	0.995	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.005	0.995	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.005	0.995	0.000
M50 Cervical disk disorders	0.000	0.995	0.005
S22.1 Multiple fractures of thoracic spine	0.005	0.995	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.005	0.995	0.000
S27.0 Traumatic pneumothorax	0.004	0.995	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.005	0.995	0.000
S20.2 Contusion of thorax	0.004	0.995	0.000
O85-O92 Complications predominantly related to the puerperium	0.004	0.995	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.3 Other injuries of lung	0.004	0.996	0.000
S27.2 Traumatic heamopneumothorax	0.004	0.996	0.000
S29 Other and unspecified injuries of thorax	0.004	0.996	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.004	0.996	0.000
S20.1 Other and unspecified superficial injuries of breast	0.004	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.004	0.996	0.000
S27.1 Traumatic haemothorax	0.004	0.996	0.000
M50.9 Cervical disk disorder, unspecified	0.000	0.996	0.004
S22.2 Fracture of sternum	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
S26 Injury of heart	0.004	0.996	0.000
M50.8 Other cervical disk disorders	0.000	0.996	0.004
O90 Complications of the puerperium, not elsewhere classified	0.004	0.996	0.000
S27.9 Injury of unspecified intrathoracic organ	0.004	0.996	0.000
S27.7 Multiple injuries of intrathoracic organs	0.004	0.996	0.000
S27.6 Injury of pleura	0.004	0.996	0.000
S27.5 Injury of thoracic trachea	0.004	0.996	0.000
S27.4 Injury of bronchus	0.004	0.996	0.000
S21 Open wound of thorax	0.004	0.996	0.000
S20.0 Contusion of breast	0.004	0.996	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.004	0.996	0.000
S25 Injury of blood vessels of thorax	0.004	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.996	0.004
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
S27.8 Injury of other specified intrathoracic organs	0.004	0.996	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.004	0.996	0.000
O89 Complications of anaesthesia during the puerperium	0.004	0.996	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.004	0.996	0.000
S20.3 Other superficial injuries of front wall of thorax	0.004	0.996	0.000
S29.9 Unspecified injury of thorax	0.004	0.996	0.000
O85 Puerperal sepsis	0.004	0.996	0.000
S24 Injury of nerves and spinal cord at thorax level	0.003	0.996	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.996	0.004
S22.11 Multiple fractures of thoracic spine (open)	0.003	0.996	0.000
S22.20 Fracture of sternum (closed)	0.004	0.996	0.000
O86 Other puerperal infections	0.004	0.996	0.000
H73.8 Other specified disorders of tympanic membrane	0.004	0.996	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.996	0.000
S20.4 Other superficial injuries of back wall of thorax	0.003	0.996	0.000
S23.4 Sprain and strain of ribs and sternum	0.003	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.003	0.996	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.996	0.000
S20.7 Multiple superficial injuries of thorax	0.003	0.996	0.000
O88 Obstetric embolism	0.003	0.996	0.000
S29.0 Injury of muscle and tendon at thorax level	0.003	0.997	0.000
O91 Infections of breast associated with childbirth	0.003	0.997	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.000	0.997	0.003
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.003	0.997	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
N18.0 End-stage renal disease	0.000	0.997	0.003
Z95.2 Presence of prosthetic heart valve	0.000	0.997	0.003
O90.0 Disruption of Caesarean section wound	0.003	0.997	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.003	0.997	0.000
S23.3 Sprain and strain of thoracic spine	0.003	0.997	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.003	0.997	0.000
S23.1 Dislocation of thoracic vertebra	0.003	0.997	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.003	0.997	0.000
S29.7 Multiple injuries of thorax	0.003	0.997	0.000
S22.50 Flail chest (closed)	0.003	0.997	0.000
O90.2 Haematoma of obstetric wound	0.003	0.997	0.000
S26.8 Other injuries of heart	0.003	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
D03 Melanoma in situ	0.003	0.997	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
O87 Venous complications in the puerperium	0.003	0.997	0.000
O80-O84 Delivery	0.003	0.997	0.000
K01.1 Impacted teeth	0.003	0.997	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.003	0.997	0.000
O90.1 Disruption of perineal obstetric wound	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.997	0.000
O92.6 Galactorrhoea	0.003	0.997	0.000
O92.5 Suppressed lactation	0.003	0.997	0.000
O92.4 Hypogalactia	0.003	0.997	0.000
O92.3 Agalactia	0.003	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
O90.5 Postpartum thyroiditis	0.003	0.997	0.000
O90.4 Postpartum acute renal failure	0.003	0.997	0.000
O90.3 Cardiomyopathy in the puerperium	0.003	0.997	0.000
S26.9 Injury of heart, unspecified	0.003	0.997	0.000
S26.0 Injury of heart with haemopericardium	0.003	0.997	0.000
O86.0 Infection of obstetric surgical wound	0.003	0.997	0.000
S21.9 Open wound of thorax, part unspecified	0.003	0.997	0.000
S21.0 Open wound of breast	0.003	0.997	0.000
O86.4 Pyrexia of unknown origin following delivery	0.003	0.997	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.003	0.997	0.000
S21.8 Open wound of other parts of thorax	0.003	0.997	0.000
S21.7 Multiple open wounds of thoracic wall	0.003	0.997	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.003	0.997	0.000
S25.8 Injury of other blood vessels of thorax	0.003	0.997	0.000
S25.7 Injury of multiple blood vessels of thorax	0.003	0.997	0.000
S25.5 Injury of intercostal blood vessels	0.003	0.997	0.000
S25.4 Injury of pulmonary blood vessels	0.003	0.997	0.000
S25.3 Injury of innominate or subclavian vein	0.003	0.997	0.000
S25.2 Injury of superior vena cava	0.003	0.997	0.000
S25.1 Injury of innominate or subclavian artery	0.003	0.997	0.000
S25.0 Injury of thoracic aorta	0.003	0.997	0.000
S28.1 Traumatic amputation of part of thorax	0.003	0.997	0.000
S28.0 Crushed chest	0.003	0.997	0.000
S21.1 Open wound of front wall of thorax	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.997	0.003
M24.16 Other articular cartilage disorders (Lower leg)	0.003	0.997	0.000
S21.2 Open wound of back wall of thorax	0.003	0.997	0.000
S22.51 Flail chest (open)	0.003	0.997	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
S22.3 Fracture of rib	0.003	0.997	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.003	0.997	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.6 Failed or difficult intubation during the puerperium	0.003	0.997	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.003	0.997	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.003	0.997	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.003	0.997	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.997	0.003
D03.7 Melanoma in situ of lower limb, including hip	0.003	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
S24.6 Injury of unspecified nerve of thorax	0.003	0.997	0.000
S24.5 Injury of other nerves of thorax	0.003	0.997	0.000
S24.4 Injury of thoracic sympathetic nerves	0.003	0.997	0.000
S24.3 Injury of peripheral nerves of thorax	0.003	0.997	0.000
S24.2 Injury of nerve root of thoracic spine	0.003	0.997	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.003	0.997	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.997	0.003
O86.8 Other specified puerperal infections	0.003	0.997	0.000
O86.3 Other genito-urinary tract infections following delivery	0.003	0.997	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
O90.9 Complication of the puerperium, unspecified	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.003	0.997	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.003	0.997	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.003	0.997	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.003	0.997	0.000
S29.8 Other specified injuries of thorax	0.003	0.997	0.000
O88.8 Other obstetric embolism	0.003	0.997	0.000
O88.3 Obstetric pyaemic and septic embolism	0.003	0.997	0.000
O88.2 Obstetric blood-clot embolism	0.003	0.997	0.000
O88.1 Amniotic fluid embolism	0.003	0.997	0.000
O88.0 Obstetric air embolism	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.003	0.997	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.003	0.997	0.000
O91.0 Infection of nipple associated with childbirth	0.003	0.997	0.000
Z45.2 Adjustment and management of vascular access device	0.000	0.997	0.003
Q63 Other congenital malformations of kidney	0.000	0.997	0.003
D03.0 Melanoma in situ of lip	0.003	0.997	0.000
D05.1 Intraductal carcinoma in situ	0.003	0.997	0.000
O86.2 Urinary tract infection following delivery	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
O91.1 Abscess of breast associated with childbirth	0.002	0.997	0.000
O81 Single delivery by forceps and vacuum extractor	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.003	0.997	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.002	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.003
O87.0 Superficial thrombophlebitis in the puerperium	0.002	0.997	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.002	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.003	0.997	0.000
O84 Multiple delivery	0.002	0.997	0.000
O83 Other assisted single delivery	0.002	0.997	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.002	0.997	0.000
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
L03.1 Cellulitis of other parts of limb	0.000	0.997	0.003
S22.0 Fracture of thoracic vertebra	0.002	0.997	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.997	0.000
O86.1 Other infection of genital tract following delivery	0.002	0.997	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.002	0.997	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.002	0.997	0.000
D03.4 Melanoma in situ of scalp and neck	0.002	0.997	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.997	0.003
I13 Hypertensive heart and renal disease	0.000	0.997	0.002
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.002	0.997	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.002	0.997	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.002	0.997	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.002	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
I15 Secondary hypertension	0.000	0.997	0.002
O81.3 Other and unspecified forceps delivery	0.002	0.997	0.000
O87.8 Other venous complications in the puerperium	0.002	0.997	0.000
Z37.2 Twins, both liveborn	0.002	0.997	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.998	0.002
I11 Hypertensive heart disease	0.000	0.998	0.002
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
D05 Carcinoma in situ of breast	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
O87.2 Haemorrhoids in the puerperium	0.002	0.998	0.000
O87.9 Venous complication in the puerperium, unspecified	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.998	0.002
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.002	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.002	0.998	0.000
O95 Obstetric death of unspecified cause	0.002	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.000	0.998	0.002
O82 Single delivery by Caesarean section	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
Q63.3 Hyperplastic and giant kidney	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.002	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.002	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
O84.2 Multiple delivery, all by Caesarean section	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
D04 Carcinoma in situ of skin	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
O83.1 Other assisted breech delivery	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations