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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76679028
log Bayes Factor = 17.8851
Chromosome 6   position 73,795,052  (GRCh37) Explore rs76679028 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.994 0.006 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.991 0.009 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
F10.1 Harmful use
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
M06.9 Rheumatoid arthritis, unspecified
0.983 0.017 0.000
K70-K77 Diseases of liver
0.983 0.017 0.000
F10.0 Acute intoxication
0.982 0.018 0.000
R26 Abnormalities of gait and mobility
0.981 0.019 0.000
I20 Angina pectoris
0.981 0.019 0.000
S00 Superficial injury of head
0.977 0.023 0.000
I30-I52 Other forms of heart disease
0.976 0.024 0.000
I21 Acute myocardial infarction
0.974 0.026 0.000
R94 Abnormal results of function studies
0.971 0.029 0.000
F10.2 Dependence syndrome
0.968 0.032 0.000
F10.3 Withdrawal state
0.967 0.033 0.000
M20-M25 Other joint disorders
0.963 0.037 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.961 0.039 0.000
R94.5 Abnormal results of liver function studies
0.957 0.043 0.000
Chapter II Neoplasms
0.947 0.053 0.000
M25 Other joint disorders, not elsewhere classified
0.943 0.057 0.000
S00.8 Superficial injury of other parts of head
0.942 0.058 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.942 0.058 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.941 0.059 0.000
M50-M54 Other dorsopathies
0.940 0.060 0.000
S01 Open wound of head
0.935 0.065 0.000
K76 Other diseases of liver
0.933 0.067 0.000
E11 Non-insulin-dependent diabetes mellitus
0.931 0.069 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.930 0.070 0.000
M70-M79 Other soft tissue disorders
0.929 0.071 0.000
Chapter I Certain infectious and parasitic diseases
0.929 0.071 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.927 0.073 0.000
M25.5 Pain in joint
0.926 0.074 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
D22 Melanocytic naevi
0.922 0.078 0.000
D10-D36 Benign neoplasms
0.922 0.078 0.000
I44 Atrioventricular and left bundle-branch block
0.918 0.082 0.000
Chapter XX External causes of morbidity and mortality
0.917 0.083 0.000
S60-S69 Injuries to the wrist and hand
0.917 0.083 0.000
E70-E90 Metabolic disorders
0.915 0.085 0.000
I20.9 Angina pectoris, unspecified
0.913 0.087 0.000
K70 Alcoholic liver disease
0.911 0.089 0.000
E20-E35 Disorders of other endocrine glands
0.910 0.090 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.910 0.090 0.000
E10 Insulin-dependent diabetes mellitus
0.909 0.091 0.000
I35 Nonrheumatic aortic valve disorders
0.909 0.091 0.000
D00-D09 In situ neoplasms
0.904 0.096 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.903 0.097 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.897 0.103 0.000
R29.6 Tendency to fall, not elsewhere classified
0.896 0.104 0.000
W00-W19 Falls
0.896 0.104 0.000
M54 Dorsalgia
0.893 0.107 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.892 0.108 0.000
K83 Other diseases of biliary tract
0.891 0.109 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.891 0.109 0.000
M13 Other arthritis
0.890 0.110 0.000
B25-B34 Other viral diseases
0.889 0.111 0.000
M25.51 Pain in joint (Shoulder region)
0.887 0.113 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.884 0.116 0.000
M45-M49 Spondylopathies
0.878 0.122 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.877 0.123 0.000
E14 Unspecified diabetes mellitus
0.876 0.124 0.000
I20.0 Unstable angina
0.875 0.125 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.875 0.125 0.000
I50 Heart failure
0.874 0.126 0.000
W19 Unspecified fall
0.874 0.126 0.000
Chapter VI Diseases of the nervous system
0.872 0.128 0.000
M80-M85 Disorders of bone density and structure
0.870 0.130 0.000
T93 Sequelae of injuries of lower limb
0.870 0.130 0.000
E11.4 With neurological complications
0.869 0.131 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.868 0.132 0.000
K72 Hepatic failure, not elsewhere classified
0.866 0.134 0.000
K86 Other diseases of pancreas
0.861 0.139 0.000
B34 Viral infection of unspecified site
0.861 0.139 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.855 0.145 0.000
I20.8 Other forms of angina pectoris
0.852 0.148 0.000
C51-C58 Malignant neoplasms of female genital organs
0.852 0.148 0.000
E10.9 Without complications
0.851 0.149 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.850 0.150 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.850 0.150 0.000
M05 Seropositive rheumatoid arthritis
0.848 0.152 0.000
M79.8 Other specified soft tissue disorders
0.847 0.153 0.000
K13 Other diseases of lip and oral mucosa
0.845 0.155 0.000
B34.9 Viral infection, unspecified
0.841 0.159 0.000
B35-B49 Mycoses
0.840 0.160 0.000
D25 Leiomyoma of uterus
0.837 0.163 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.837 0.163 0.000
S00.1 Contusion of eyelid and periocular area
0.837 0.163 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.837 0.163 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.835 0.165 0.000
D22.5 Melanocytic naevi of trunk
0.833 0.167 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.832 0.168 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.832 0.168 0.000
D22.4 Melanocytic naevi of scalp and neck
0.830 0.170 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.827 0.173 0.000
S80-S89 Injuries to the knee and lower leg
0.824 0.176 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.823 0.177 0.000
S40-S49 Injuries to the shoulder and upper arm
0.819 0.180 0.000
M47 Spondylosis
0.819 0.181 0.000
M31 Other necrotising vasculopathies
0.819 0.181 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.819 0.181 0.000
E78.0 Pure hypercholesterolaemia
0.814 0.186 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.814 0.186 0.000
O60-O75 Complications of labour and delivery
0.812 0.188 0.000
S00.3 Superficial injury of nose
0.811 0.189 0.000
K40-K46 Hernia
0.811 0.189 0.000
I24 Other acute ischaemic heart diseases
0.810 0.190 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.809 0.190 0.000
I21.4 Acute subendocardial myocardial infarction
0.808 0.192 0.000
M54.1 Radiculopathy
0.806 0.194 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.806 0.194 0.000
S70-S79 Injuries to the hip and thigh
0.805 0.195 0.000
S01.0 Open wound of scalp
0.803 0.197 0.000
K83.0 Cholangitis
0.803 0.197 0.000
I46 Cardiac arrest
0.802 0.198 0.000
I44.7 Left bundle-branch block, unspecified
0.802 0.198 0.000
M25.54 Pain in joint (Hand)
0.802 0.198 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.801 0.199 0.000
D03 Melanoma in situ
0.801 0.199 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.799 0.201 0.000
F10.4 Withdrawal state with delirium
0.797 0.203 0.000
M10 Gout
0.796 0.204 0.000
K08 Other disorders of teeth and supporting structures
0.796 0.204 0.000
S01.8 Open wound of other parts of head
0.795 0.205 0.000
M13.9 Arthritis, unspecified
0.794 0.206 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.791 0.209 0.000
M21 Other acquired deformities of limbs
0.791 0.209 0.000
W19.9 Unspecified place
0.790 0.210 0.000
T93.2 Sequelae of other fractures of lower limb
0.790 0.210 0.000
E40-E46 Malnutrition
0.788 0.211 0.000
K83.8 Other specified diseases of biliary tract
0.788 0.212 0.000
M25.3 Other instability of joint
0.787 0.213 0.000
E16 Other disorders of pancreatic internal secretion
0.786 0.214 0.000
I31 Other diseases of pericardium
0.784 0.216 0.000
M06.3 Rheumatoid nodule
0.783 0.217 0.000
K72.9 Hepatic failure, unspecified
0.783 0.217 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.780 0.220 0.000
S64 Injury of nerves at wrist and hand level
0.780 0.220 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.779 0.221 0.000
W19.2 School, other institution and public administrative area
0.779 0.221 0.000
K70.3 Alcoholic cirrhosis of liver
0.778 0.222 0.000
I49 Other cardiac arrhythmias
0.778 0.222 0.000
K75 Other inflammatory liver diseases
0.777 0.223 0.000
B37 Candidiasis
0.777 0.223 0.000
M47.9 Spondylosis, unspecified
0.773 0.227 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.772 0.228 0.000
I35.1 Aortic (valve) insufficiency
0.771 0.229 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.771 0.229 0.000
E23 Hypofunction and other disorders of pituitary gland
0.770 0.230 0.000
I50.1 Left ventricular failure
0.770 0.230 0.000
M79.1 Myalgia
0.769 0.231 0.000
I21.9 Acute myocardial infarction, unspecified
0.769 0.231 0.000
E29 Testicular dysfunction
0.767 0.233 0.000
R27 Other lack of coordination
0.767 0.233 0.000
K11 Diseases of salivary glands
0.766 0.234 0.000
E11.9 Without complications
0.765 0.235 0.000
V20-V29 Motorcycle rider injured in transport accident
0.764 0.236 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.762 0.238 0.000
W20-W49 Exposure to inanimate mechanical forces
0.762 0.238 0.000
K43 Ventral hernia
0.761 0.239 0.000
M85 Other disorders of bone density and structure
0.760 0.240 0.000
M65-M68 Disorders of synovium and tendon
0.759 0.241 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.758 0.242 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.758 0.242 0.000
S20-S29 Injuries to the thorax
0.756 0.244 0.000
R26.3 Immobility
0.755 0.245 0.000
I44.0 Atrioventricular block, first degree
0.754 0.246 0.000
I35.9 Aortic valve disorder, unspecified
0.753 0.246 0.000
S67 Crushing injury of wrist and hand
0.752 0.248 0.000
T79-T79 Certain early complications of trauma
0.751 0.249 0.000
I22 Subsequent myocardial infarction
0.750 0.250 0.000
W19.4 Street and highway
0.748 0.252 0.000
C54 Malignant neoplasm of corpus uteri
0.748 0.252 0.000
E14.9 Without complications
0.748 0.252 0.000
S62 Fracture at wrist and hand level
0.747 0.253 0.000
M51 Other intervertebral disk disorders
0.747 0.253 0.000
I44.6 Other and unspecified fascicular block
0.746 0.254 0.000
M06.0 Seronegative rheumatoid arthritis
0.746 0.254 0.000
I33 Acute and subacute endocarditis
0.746 0.254 0.000
M91-M94 Chondropathies
0.745 0.255 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.744 0.256 0.000
R47-R49 Symptoms and signs involving speech and voice
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
M24 Other specific joint derangements
0.742 0.258 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.742 0.258 0.000
S50-S59 Injuries to the elbow and forearm
0.741 0.259 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.741 0.259 0.000
E11.3 With ophthalmic complications
0.739 0.261 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.738 0.262 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.738 0.262 0.000
I35.0 Aortic (valve) stenosis
0.736 0.264 0.000
S00.9 Superficial injury of head, part unspecified
0.736 0.264 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.735 0.265 0.000
S06 Intracranial injury
0.734 0.266 0.000
K70.9 Alcoholic liver disease, unspecified
0.733 0.267 0.000
K10 Other diseases of jaws
0.733 0.267 0.000
D25.2 Subserosal leiomyoma of uterus
0.733 0.267 0.000
K76.6 Portal hypertension
0.731 0.269 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.731 0.269 0.000
E50-E64 Other nutritional deficiencies
0.731 0.269 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.730 0.270 0.000
M25.53 Pain in joint (Forearm)
0.730 0.270 0.000
R40 Somnolence, stupor and coma
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.271 0.000
D35.2 Pituitary gland
0.728 0.271 0.000
M07 Psoriatic and enteropathic arthropathies
0.728 0.272 0.000
K70.1 Alcoholic hepatitis
0.728 0.272 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.727 0.272 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.272 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.727 0.273 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.726 0.274 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.726 0.274 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.726 0.274 0.000
M54.9 Dorsalgia, unspecified
0.726 0.274 0.000
I50.0 Congestive heart failure
0.725 0.275 0.000
T66-T78 Other and unspecified effects of external causes
0.724 0.276 0.000
S01.2 Open wound of nose
0.723 0.277 0.000
E16.2 Hypoglycaemia, unspecified
0.723 0.277 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.723 0.277 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.722 0.277 0.000
M25.52 Pain in joint (Upper arm)
0.722 0.278 0.000
M54.4 Lumbago with sciatica
0.722 0.278 0.000
Chapter XXI Factors influencing health status and contact with health services
0.721 0.279 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.720 0.280 0.000
M25.50 Pain in joint (Multiple sites)
0.720 0.280 0.000
O80-O84 Delivery
0.720 0.280 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.720 0.280 0.000
K86.9 Disease of pancreas, unspecified
0.718 0.282 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.718 0.282 0.000
E14.3 With ophthalmic complications
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F10.9 Unspecified mental and behavioural disorder
0.717 0.283 0.000
F10.8 Other mental and behavioural disorders
0.717 0.283 0.000
F10.7 Residual and late-onset psychotic disorder
0.717 0.283 0.000
F10.6 Amnesic syndrome
0.717 0.283 0.000
F10.5 Psychotic disorder
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.283 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.716 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.283 0.000
F99-F99 Unspecified mental disorder
0.716 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
F80-F89 Disorders of psychological development
0.716 0.283 0.000
F70-F79 Mental retardation
0.716 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M31.6 Other giant cell arteritis
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.715 0.285 0.000
D10 Benign neoplasm of mouth and pharynx
0.715 0.285 0.000
S09 Other and unspecified injuries of head
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.713 0.287 0.000
S07 Crushing injury of head
0.713 0.287 0.000
S05 Injury of eye and orbit
0.713 0.287 0.000
S04 Injury of cranial nerves
0.713 0.287 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.713 0.287 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.713 0.287 0.000
D04 Carcinoma in situ of skin
0.713 0.287 0.000
S02 Fracture of skull and facial bones
0.712 0.288 0.000
I44.2 Atrioventricular block, complete
0.712 0.288 0.000
S32 Fracture of lumbar spine and pelvis
0.711 0.289 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.711 0.289 0.000
R73 Elevated blood glucose level
0.711 0.289 0.000
I35.8 Other aortic valve disorders
0.711 0.289 0.000
M06.8 Other specified rheumatoid arthritis
0.710 0.289 0.000
M06.4 Inflammatory polyarthropathy
0.710 0.289 0.000
M06.2 Rheumatoid bursitis
0.710 0.289 0.000
M06.1 Adult-onset Still's disease
0.710 0.289 0.000
I20.1 Angina pectoris with documented spasm
0.710 0.290 0.000
M35 Other systemic involvement of connective tissue
0.710 0.290 0.000
M40-M43 Deforming dorsopathies
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.709 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.290 0.000
M25.4 Effusion of joint
0.709 0.290 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.709 0.291 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.708 0.292 0.000
O72 Postpartum haemorrhage
0.708 0.292 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.707 0.293 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
S42 Fracture of shoulder and upper arm
0.706 0.294 0.000
R41.3 Other amnesia
0.705 0.295 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.705 0.295 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.705 0.295 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.705 0.295 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.705 0.295 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.705 0.295 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.705 0.295 0.000
K77 Liver disorders in diseases classified elsewhere
0.705 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.705 0.295 0.000
K71 Toxic liver disease
0.705 0.295 0.000
K86.2 Cyst of pancreas
0.705 0.295 0.000
R26.1 Paralytic gait
0.704 0.296 0.000
R26.0 Ataxic gait
0.704 0.296 0.000
K70.4 Alcoholic hepatic failure
0.703 0.297 0.000
S01.5 Open wound of lip and oral cavity
0.702 0.298 0.000
S00.7 Multiple superficial injuries of head
0.700 0.300 0.000
S00.5 Superficial injury of lip and oral cavity
0.700 0.300 0.000
S00.4 Superficial injury of ear
0.700 0.300 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.700 0.300 0.000
L20-L30 Dermatitis and eczema
0.700 0.300 0.000
I52 Other heart disorders in diseases classified elsewhere
0.700 0.300 0.000
I48 Atrial fibrillation and flutter
0.700 0.300 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.700 0.300 0.000
I41 Myocarditis in diseases classified elsewhere
0.700 0.300 0.000
I40 Acute myocarditis
0.700 0.300 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.700 0.300 0.000
I37 Pulmonary valve disorders
0.700 0.300 0.000
I36 Nonrheumatic tricuspid valve disorders
0.700 0.300 0.000
I32 Pericarditis in diseases classified elsewhere
0.700 0.300 0.000
I30 Acute pericarditis
0.700 0.300 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.699 0.301 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.699 0.301 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.698 0.302 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.698 0.302 0.000
I45 Other conduction disorders
0.698 0.302 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.696 0.304 0.000
R94.7 Abnormal results of other endocrine function studies
0.696 0.304 0.000
R94.6 Abnormal results of thyroid function studies
0.696 0.304 0.000
R94.4 Abnormal results of kidney function studies
0.696 0.304 0.000
R94.2 Abnormal results of pulmonary function studies
0.696 0.304 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.696 0.304 0.000
R94.0 Abnormal results of function studies of central nervous system
0.696 0.304 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.696 0.304 0.000
R41.2 Retrograde amnesia
0.695 0.305 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.695 0.305 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.694 0.306 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.694 0.306 0.000
K07 Dentofacial anomalies [including malocclusion]
0.694 0.306 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.694 0.306 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.693 0.307 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.693 0.307 0.000
K14 Diseases of tongue
0.692 0.308 0.000
K05 Gingivitis and periodontal diseases
0.692 0.308 0.000
K65-K67 Diseases of peritoneum
0.692 0.308 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.692 0.308 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.692 0.308 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.691 0.309 0.000
K74 Fibrosis and cirrhosis of liver
0.691 0.309 0.000
K86.1 Other chronic pancreatitis
0.691 0.309 0.000
W10 Fall on and from stairs and steps
0.691 0.309 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M34 Systemic sclerosis
0.690 0.310 0.000
M33 Dermatopolymyositis
0.690 0.310 0.000
M32 Systemic lupus erythematosus
0.690 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.310 0.000
D05 Carcinoma in situ of breast
0.690 0.310 0.000
D07.5 Prostate
0.690 0.310 0.000
M54.16 Radiculopathy (Lumbar region)
0.690 0.310 0.000
S68 Traumatic amputation of wrist and hand
0.690 0.310 0.000
R25 Abnormal involuntary movements
0.688 0.312 0.000
B37.3 Candidiasis of vulva and vagina
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.688 0.312 0.000
R45 Symptoms and signs involving emotional state
0.687 0.313 0.000
M13.0 Polyarthritis, unspecified
0.687 0.313 0.000
E83 Disorders of mineral metabolism
0.687 0.313 0.000
D35.1 Parathyroid gland
0.686 0.314 0.000
W08 Fall involving other furniture
0.685 0.315 0.000
S01.1 Open wound of eyelid and periocular area
0.684 0.315 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.684 0.316 0.000
E89.0 Postprocedural hypothyroidism
0.683 0.317 0.000
M79.10 Myalgia (Multiple sites)
0.682 0.318 0.000
M85.8 Other specified disorders of bone density and structure
0.682 0.318 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.681 0.319 0.000
S01.3 Open wound of ear
0.680 0.320 0.000
E27 Other disorders of adrenal gland
0.679 0.320 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.679 0.321 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.679 0.321 0.000
S01.9 Open wound of head, part unspecified
0.679 0.321 0.000
M84 Disorders of continuity of bone
0.679 0.321 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.679 0.321 0.000
K76.9 Liver disease, unspecified
0.678 0.321 0.000
K82 Other diseases of gallbladder
0.678 0.322 0.000
S81 Open wound of lower leg
0.678 0.322 0.000
E88 Other metabolic disorders
0.678 0.322 0.000
R94.3 Abnormal results of cardiovascular function studies
0.676 0.323 0.000
M25.9 Joint disorder, unspecified
0.676 0.323 0.000
M25.8 Other specified joint disorders
0.676 0.323 0.000
M25.2 Flail joint
0.676 0.323 0.000
M25.1 Fistula of joint
0.676 0.323 0.000
M25.0 Haemarthrosis
0.676 0.323 0.000
D36 Benign neoplasm of other and unspecified sites
0.676 0.324 0.000
M22 Disorders of patella
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.324 0.000
M25.37 Other instability of joint (Ankle and foot)
0.675 0.324 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.675 0.325 0.000
D25.1 Intramural leiomyoma of uterus
0.675 0.325 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.675 0.325 0.000
M53 Other dorsopathies, not elsewhere classified
0.674 0.326 0.000
C54.1 Endometrium
0.673 0.327 0.000
M79.0 Rheumatism, unspecified
0.673 0.327 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.671 0.329 0.000
M72 Fibroblastic disorders
0.671 0.329 0.000
C56 Malignant neoplasm of ovary
0.670 0.329 0.000
S01.7 Multiple open wounds of head
0.670 0.330 0.000
S01.4 Open wound of cheek and temporomandibular area
0.670 0.330 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.670 0.330 0.000
E23.0 Hypopituitarism
0.670 0.330 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.669 0.331 0.000
D26 Other benign neoplasms of uterus
0.669 0.331 0.000
I31.9 Disease of pericardium, unspecified
0.669 0.331 0.000
K76.7 Hepatorenal syndrome
0.669 0.331 0.000
K76.5 Hepatic veno-occlusive disease
0.669 0.331 0.000
K76.4 Peliosis hepatis
0.669 0.331 0.000
K76.3 Infarction of liver
0.669 0.331 0.000
K76.2 Central haemorrhagic necrosis of liver
0.669 0.331 0.000
K76.1 Chronic passive congestion of liver
0.669 0.331 0.000
E11.8 With unspecified complications
0.668 0.332 0.000
E11.7 With multiple complications
0.668 0.332 0.000
E11.6 With other specified complications
0.668 0.332 0.000
E11.1 With ketoacidosis
0.668 0.332 0.000
E11.0 With coma
0.668 0.332 0.000
G61 Inflammatory polyneuropathy
0.667 0.333 0.000
K09 Cysts of oral region, not elsewhere classified
0.667 0.333 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.667 0.333 0.000
K03 Other diseases of hard tissues of teeth
0.667 0.333 0.000
K00 Disorders of tooth development and eruption
0.667 0.333 0.000
M76 Enthesopathies of lower limb, excluding foot
0.666 0.334 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.666 0.334 0.000
B99-B99 Other infectious diseases
0.666 0.334 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.666 0.334 0.000
B65-B83 Helminthiases
0.666 0.334 0.000
B50-B64 Protozoal diseases
0.666 0.334 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.666 0.334 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.666 0.334 0.000
A80-A89 Viral infections of the central nervous system
0.666 0.334 0.000
A75-A79 Rickettsioses
0.666 0.334 0.000
A70-A74 Other diseases caused by chlamydiae
0.666 0.334 0.000
A65-A69 Other spirochaetal diseases
0.666 0.334 0.000
A20-A28 Certain zoonotic bacterial diseases
0.666 0.334 0.000
A15-A19 Tuberculosis
0.666 0.334 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.666 0.334 0.000
K76.8 Other specified diseases of liver
0.665 0.334 0.000
E29.1 Testicular hypofunction
0.665 0.335 0.000
M11 Other crystal arthropathies
0.664 0.335 0.000
S82 Fracture of lower leg, including ankle
0.664 0.335 0.000
R29.4 Clicking hip
0.664 0.336 0.000
R29.3 Abnormal posture
0.664 0.336 0.000
R29.2 Abnormal reflex
0.664 0.336 0.000
R29.1 Meningismus
0.664 0.336 0.000
R29.0 Tetany
0.664 0.336 0.000
M25.59 Pain in joint (Site unspecified)
0.664 0.336 0.000
M25.58 Pain in joint (Other)
0.664 0.336 0.000
B15-B19 Viral hepatitis
0.663 0.337 0.000
M54.5 Low back pain
0.663 0.337 0.000
K41 Femoral hernia
0.663 0.337 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.663 0.337 0.000
T98 Sequelae of other and unspecified effects of external causes
0.662 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.662 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.662 0.337 0.000
T92 Sequelae of injuries of upper limb
0.662 0.337 0.000
T91 Sequelae of injuries of neck and trunk
0.662 0.337 0.000
T90 Sequelae of injuries of head
0.662 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.662 0.337 0.000
D22.9 Melanocytic naevi, unspecified
0.661 0.339 0.000
D22.0 Melanocytic naevi of lip
0.661 0.339 0.000
B37.0 Candidal stomatitis
0.661 0.339 0.000
D31 Benign neoplasm of eye and adnexa
0.661 0.339 0.000
D30 Benign neoplasm of urinary organs
0.661 0.339 0.000
D29 Benign neoplasm of male genital organs
0.661 0.339 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.661 0.339 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.661 0.339 0.000
D19 Benign neoplasm of mesothelial tissue
0.661 0.339 0.000
D16 Benign neoplasm of bone and articular cartilage
0.661 0.339 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.661 0.339 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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