TreeWAS – Variant ID: rs76925404

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter V Mental and behavioural disorders	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
F30-F39 Mood [affective] disorders	0.997	0.003	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005	0.000
Chapter XX External causes of morbidity and mortality	0.994	0.006	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.983	0.017	0.000
S10-S19 Injuries to the neck	0.978	0.022	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.976	0.024	0.000
F31 Bipolar affective disorder	0.967	0.033	0.000
M20-M25 Other joint disorders	0.964	0.036	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.962	0.038	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.961	0.039	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.960	0.040	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.959	0.041	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.956	0.044	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.954	0.046	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.953	0.047	0.000
M70-M79 Other soft tissue disorders	0.942	0.058	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.939	0.061	0.000
M40-M43 Deforming dorsopathies	0.929	0.071	0.000
M25 Other joint disorders, not elsewhere classified	0.927	0.073	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.925	0.075	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.925	0.075	0.000
S20-S29 Injuries to the thorax	0.924	0.076	0.000
M34 Systemic sclerosis	0.921	0.079	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.920	0.080	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.918	0.082	0.000
T40.2 Other opioids	0.917	0.083	0.000
R45 Symptoms and signs involving emotional state	0.914	0.086	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.914	0.086	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.913	0.087	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.911	0.089	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.907	0.093	0.000
T39.0 Salicylates	0.907	0.093	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.906	0.094	0.000
M79.7 Fibromyalgia	0.900	0.100	0.000
F33 Recurrent depressive disorder	0.896	0.104	0.000
F60-F69 Disorders of adult personality and behaviour	0.894	0.106	0.000
W00-W19 Falls	0.893	0.107	0.000
Q60-Q64 Congenital malformations of the urinary system	0.891	0.109	0.000
F99-F99 Unspecified mental disorder	0.886	0.114	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.886	0.114	0.000
M79.79 Fibromyalgia (Site unspecified)	0.883	0.117	0.000
M80-M85 Disorders of bone density and structure	0.881	0.119	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.876	0.124	0.000
F30 Manic episode	0.876	0.124	0.000
F10.3 Withdrawal state	0.874	0.126	0.000
S19 Other and unspecified injuries of neck	0.871	0.129	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.870	0.130	0.000
Chapter XXII Codes for special purposes	0.869	0.131	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.869	0.131	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.868	0.132	0.000
R63.0 Anorexia	0.868	0.132	0.000
R63 Symptoms and signs concerning food and fluid intake	0.867	0.133	0.000
R50-R69 General symptoms and signs	0.866	0.134	0.000
M25.3 Other instability of joint	0.866	0.134	0.000
X60-X84 Intentional self-harm	0.865	0.135	0.000
Q61 Cystic kidney disease	0.865	0.135	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.865	0.135	0.000
D68 Other coagulation defects	0.864	0.136	0.000
R45.8 Other symptoms and signs involving emotional state	0.862	0.138	0.000
M86-M90 Other osteopathies	0.861	0.139	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.861	0.139	0.000
S90-S99 Injuries to the ankle and foot	0.861	0.139	0.000
D80-D89 Certain disorders involving the immune mechanism	0.854	0.146	0.000
M25.5 Pain in joint	0.852	0.148	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.852	0.148	0.000
M71 Other bursopathies	0.851	0.149	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.851	0.149	0.000
T93 Sequelae of injuries of lower limb	0.850	0.150	0.000
M43 Other deforming dorsopathies	0.844	0.156	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.844	0.156	0.000
M40 Kyphosis and lordosis	0.842	0.158	0.000
M34.9 Systemic sclerosis, unspecified	0.841	0.159	0.000
M33 Dermatopolymyositis	0.836	0.163	0.000
R41.0 Disorientation, unspecified	0.835	0.165	0.000
T23 Burn and corrosion of wrist and hand	0.833	0.167	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.833	0.167	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.832	0.168	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.831	0.169	0.000
M79.0 Rheumatism, unspecified	0.830	0.170	0.000
F10.4 Withdrawal state with delirium	0.828	0.172	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.827	0.173	0.000
Q61.3 Polycystic kidney, unspecified	0.825	0.175	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.824	0.176	0.000
S12 Fracture of neck	0.820	0.180	0.000
M25.56 Pain in joint (Lower leg)	0.818	0.182	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.818	0.182	0.000
M60-M63 Disorders of muscles	0.816	0.183	0.000
V80-V89 Other land transport accidents	0.816	0.184	0.000
W20-W49 Exposure to inanimate mechanical forces	0.816	0.184	0.000
F32 Depressive episode	0.815	0.185	0.000
M21 Other acquired deformities of limbs	0.815	0.185	0.000
T20 Burn and corrosion of head and neck	0.815	0.185	0.000
M34.1 CR(E)ST syndrome	0.815	0.185	0.000
F44 Dissociative [conversion] disorders	0.814	0.186	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.814	0.186	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.813	0.187	0.000
F11 Mental and behavioural disorders due to use of opioids	0.811	0.189	0.000
M79.5 Residual foreign body in soft tissue	0.810	0.190	0.000
F39 Unspecified mood [affective] disorder	0.806	0.194	0.000
M24 Other specific joint derangements	0.806	0.194	0.000
F99 Mental disorder, not otherwise specified	0.804	0.196	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.803	0.197	0.000
M25.31 Other instability of joint (Shoulder region)	0.800	0.200	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.800	0.200	0.000
R41.2 Retrograde amnesia	0.799	0.201	0.000
T42.4 Benzodiazepines	0.799	0.201	0.000
F31.9 Bipolar affective disorder, unspecified	0.798	0.202	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.798	0.202	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.796	0.204	0.000
S21 Open wound of thorax	0.793	0.206	0.000
S92 Fracture of foot, except ankle	0.791	0.209	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.791	0.209	0.000
R46 Symptoms and signs involving appearance and behaviour	0.790	0.210	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.790	0.210	0.000
R35 Polyuria	0.790	0.210	0.000
M84 Disorders of continuity of bone	0.790	0.210	0.000
R30-R39 Symptoms and signs involving the urinary system	0.788	0.212	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.787	0.213	0.000
T79-T79 Certain early complications of trauma	0.787	0.213	0.000
F30.9 Manic episode, unspecified	0.786	0.213	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.785	0.215	0.000
F60 Specific personality disorders	0.784	0.216	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.783	0.217	0.000
M91-M94 Chondropathies	0.782	0.218	0.000
W50-W64 Exposure to animate mechanical forces	0.780	0.220	0.000
M85 Other disorders of bone density and structure	0.780	0.220	0.000
T90 Sequelae of injuries of head	0.779	0.221	0.000
R52 Pain, not elsewhere classified	0.779	0.221	0.000
Y00-Y09 Assault	0.778	0.221	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.778	0.222	0.000
W06 Fall involving bed	0.776	0.223	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.775	0.225	0.000
V40-V49 Car occupant injured in transport accident	0.773	0.227	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.772	0.228	0.000
D68.5 Primary Thrombophilia	0.768	0.232	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.765	0.235	0.000
M79.70 Fibromyalgia (Multiple sites)	0.765	0.235	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.764	0.236	0.000
V01-V09 Pedestrian injured in transport accident	0.763	0.237	0.000
T40.6 Other and unspecified narcotics	0.762	0.238	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.762	0.238	0.000
W07 Fall involving chair	0.760	0.240	0.000
M43.0 Spondylolysis	0.758	0.242	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.757	0.243	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.757	0.243	0.000
M86 Osteomyelitis	0.757	0.243	0.000
Q80-Q89 Other congenital malformations	0.756	0.244	0.000
T93.0 Sequelae of open wound of lower limb	0.756	0.244	0.000
D68.2 Hereditary deficiency of other clotting factors	0.755	0.245	0.000
F80-F89 Disorders of psychological development	0.753	0.247	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.752	0.248	0.000
D60-D64 Aplastic and other anaemias	0.752	0.248	0.000
R43 Disturbances of smell and taste	0.752	0.248	0.000
X50-X57 Overexertion, travel and privation	0.750	0.250	0.000
R56 Convulsions, not elsewhere classified	0.749	0.251	0.000
R40 Somnolence, stupor and coma	0.749	0.251	0.000
W75-W84 Other accidental threats to breathing	0.749	0.251	0.000
T25 Burn and corrosion of ankle and foot	0.747	0.253	0.000
R45.1 Restlessness and agitation	0.746	0.254	0.000
Q61.2 Polycystic kidney, adult type	0.746	0.254	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.744	0.256	0.000
S10 Superficial injury of neck	0.744	0.256	0.000
T42.0 Hydantoin derivatives	0.744	0.256	0.000
Y40 Systemic antibiotics	0.743	0.257	0.000
D69 Purpura and other haemorrhagic conditions	0.741	0.259	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.741	0.259	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.740	0.260	0.000
S13.1 Dislocation of cervical vertebra	0.740	0.260	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.738	0.262	0.000
M33.1 Other dermatomyositis	0.736	0.264	0.000
S19.8 Other specified injuries of neck	0.735	0.265	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.735	0.265	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.733	0.267	0.000
R58 Haemorrhage, not elsewhere classified	0.733	0.267	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.733	0.267	0.000
S19.9 Unspecified injury of neck	0.733	0.267	0.000
M00-M03 Infectious arthropathies	0.732	0.268	0.000
T00-T07 Injuries involving multiple body regions	0.732	0.268	0.000
S14 Injury of nerves and spinal cord at neck level	0.727	0.273	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.727	0.273	0.000
M40.2 Other and unspecified kyphosis	0.726	0.274	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.725	0.274	0.000
T36 Poisoning by systemic antibiotics	0.724	0.276	0.000
D55-D59 Haemolytic anaemias	0.724	0.276	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.723	0.276	0.000
F10.2 Dependence syndrome	0.723	0.277	0.000
V20-V29 Motorcycle rider injured in transport accident	0.721	0.279	0.000
F33.9 Recurrent depressive disorder, unspecified	0.720	0.280	0.000
M25.7 Osteophyte	0.720	0.280	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.720	0.280	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.719	0.281	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.718	0.282	0.000
M45-M49 Spondylopathies	0.718	0.282	0.000
F50 Eating disorders	0.718	0.282	0.000
F42 Obsessive-compulsive disorder	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
S20 Superficial injury of thorax	0.717	0.283	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.716	0.284	0.000
X10-X19 Contact with heat and hot substances	0.716	0.284	0.000
T40.4 Other synthetic narcotics	0.716	0.284	0.000
M40.5 Lordosis, unspecified	0.715	0.285	0.000
S27 Injury of other and unspecified intrathoracic organs	0.715	0.285	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.715	0.285	0.000
F38 Other mood [affective] disorders	0.715	0.285	0.000
Y48 Anaesthetics and therapeutic gases	0.714	0.286	0.000
Y35-Y36 Legal intervention and operations of war	0.713	0.287	0.000
Y10-Y34 Event of undetermined intent	0.713	0.287	0.000
X85-X99 Assault	0.713	0.287	0.000
X30-X39 Exposure to forces of nature	0.713	0.287	0.000
X00-X09 Exposure to smoke, fire and flames	0.713	0.287	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.713	0.287	0.000
W65-W74 Accidental drowning and submersion	0.713	0.287	0.000
V98-V99 Other and unspecified transport accidents	0.713	0.287	0.000
V95-V97 Air and space transport accidents	0.713	0.287	0.000
V90-V94 Water transport accidents	0.713	0.287	0.000
V70-V79 Bus occupant injured in transport accident	0.713	0.287	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.713	0.287	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.713	0.287	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.713	0.287	0.000
R45.0 Nervousness	0.712	0.287	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.711	0.289	0.000
F32.1 Moderate depressive episode	0.710	0.290	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.710	0.290	0.000
M76 Enthesopathies of lower limb, excluding foot	0.709	0.290	0.000
W14 Fall from tree	0.709	0.291	0.000
F70-F79 Mental retardation	0.709	0.291	0.000
V10-V19 Pedal cyclist injured in transport accident	0.708	0.292	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.707	0.293	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.706	0.294	0.000
D68.6 Other Thrombophilia	0.706	0.294	0.000
M25.52 Pain in joint (Upper arm)	0.706	0.294	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.705	0.295	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.705	0.295	0.000
T42.3 Barbiturates	0.705	0.295	0.000
T42.2 Succinimides and oxazolidinediones	0.705	0.295	0.000
M24.5 Contracture of joint	0.704	0.296	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.703	0.297	0.000
R57 Shock, not elsewhere classified	0.703	0.297	0.000
U88 Agent resistant to multiple antibiotics	0.702	0.298	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.702	0.298	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.701	0.298	0.000
S17 Crushing injury of neck	0.701	0.299	0.000
S15 Injury of blood vessels at neck level	0.701	0.299	0.000
S18 Traumatic amputation at neck level	0.701	0.299	0.000
S16 Injury of muscle and tendon at neck level	0.701	0.299	0.000
S11 Open wound of neck	0.701	0.299	0.000
M25.34 Other instability of joint (Hand)	0.701	0.299	0.000
M25.33 Other instability of joint (Forearm)	0.700	0.300	0.000
T39.4 Antirheumatics, not elsewhere classified	0.700	0.300	0.000
T39.2 Pyrazolone derivatives	0.700	0.300	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.700	0.300	0.000
Y45.0 Opioids and related analgesics	0.698	0.302	0.000
T42.1 Iminostilbenes	0.697	0.302	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.696	0.303	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.696	0.304	0.000
M72 Fibroblastic disorders	0.696	0.304	0.000
R36 Urethral discharge	0.696	0.304	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.695	0.305	0.000
F44.4 Dissociative motor disorders	0.694	0.306	0.000
M21.8 Other specified acquired deformities of limbs	0.694	0.306	0.000
S70-S79 Injuries to the hip and thigh	0.694	0.306	0.000
F31.8 Other bipolar affective disorders	0.693	0.306	0.000
F31.7 Bipolar affective disorder, currently in remission	0.693	0.306	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.693	0.307	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.693	0.307	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.692	0.308	0.000
F69 Unspecified disorder of adult personality and behaviour	0.691	0.309	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.691	0.309	0.000
F43 Reaction to severe stress, and adjustment disorders	0.691	0.309	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.690	0.309	0.000
S29 Other and unspecified injuries of thorax	0.690	0.310	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.690	0.310	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.690	0.310	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.689	0.310	0.000
T90.5 Sequelae of intracranial injury	0.689	0.311	0.000
M48 Other spondylopathies	0.689	0.311	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.689	0.311	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.689	0.311	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.688	0.311	0.000
T40.8 Lysergide [LSD]	0.688	0.311	0.000
T40.7 Cannabis (derivatives)	0.688	0.311	0.000
T40.5 Cocaine	0.688	0.311	0.000
T40.3 Methadone	0.688	0.311	0.000
T40.1 Heroin	0.688	0.311	0.000
T40.0 Opium	0.688	0.311	0.000
S12.2 Fracture of other specified cervical vertebra	0.688	0.312	0.000
T21 Burn and corrosion of trunk	0.688	0.312	0.000
F12.1 Harmful use	0.688	0.312	0.000
X62.9 Unspecified place	0.688	0.312	0.000
F60.9 Personality disorder, unspecified	0.687	0.313	0.000
F10.5 Psychotic disorder	0.687	0.313	0.000
M86.9 Osteomyelitis, unspecified	0.687	0.313	0.000
R52.1 Chronic intractable pain	0.686	0.314	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.686	0.314	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.686	0.314	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.686	0.314	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.686	0.314	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.686	0.314	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.684	0.316	0.000
M24.2 Disorder of ligament	0.682	0.318	0.000
M43.06 Spondylolysis (Lumbar region)	0.682	0.318	0.000
W20 Struck by thrown, projected or falling object	0.680	0.320	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.679	0.321	0.000
M34.8 Other forms of systemic sclerosis	0.679	0.321	0.000
T20.0 Burn of unspecified degree of head and neck	0.678	0.322	0.000
F11.1 Harmful use	0.676	0.324	0.000
Y57 Other and unspecified drugs and medicaments	0.676	0.324	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.675	0.325	0.000
F23 Acute and transient psychotic disorders	0.675	0.325	0.000
W06.0 Home	0.675	0.325	0.000
M84.0 Malunion of fracture	0.674	0.326	0.000
M88 Paget's disease of bone [osteitis deformans]	0.674	0.326	0.000
R40.0 Somnolence	0.674	0.326	0.000
Q35-Q37 Cleft lip and cleft palate	0.673	0.327	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.673	0.327	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.673	0.327	0.000
F64 Gender identity disorders	0.673	0.327	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.672	0.328	0.000
M43.6 Torticollis	0.671	0.328	0.000
D62 Acute posthaemorrhagic anaemia	0.671	0.329	0.000
R63.1 Polydipsia	0.671	0.329	0.000
D80 Immunodeficiency with predominantly antibody defects	0.670	0.330	0.000
R52.2 Other chronic pain	0.670	0.330	0.000
M80 Osteoporosis with pathological fracture	0.669	0.331	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.668	0.331	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.667	0.333	0.000
M32 Systemic lupus erythematosus	0.666	0.334	0.000
M42 Spinal osteochondrosis	0.666	0.334	0.000
R56.8 Other and unspecified convulsions	0.666	0.334	0.000
T20.1 Burn of first degree of head and neck	0.666	0.334	0.000
M62 Other disorders of muscle	0.665	0.335	0.000
S92.5 Fracture of other toe	0.665	0.335	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.665	0.335	0.000
M25.2 Flail joint	0.665	0.335	0.000
M25.1 Fistula of joint	0.665	0.335	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.664	0.335	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.664	0.336	0.000
Y52 Agents primarily affecting the cardiovascular system	0.664	0.336	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.663	0.337	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.663	0.337	0.000
S26 Injury of heart	0.663	0.337	0.000
S25 Injury of blood vessels of thorax	0.663	0.337	0.000
S24 Injury of nerves and spinal cord at thorax level	0.663	0.337	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.663	0.337	0.000
M48.0 Spinal stenosis	0.662	0.338	0.000
F10.6 Amnesic syndrome	0.662	0.338	0.000
S50-S59 Injuries to the elbow and forearm	0.662	0.338	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.661	0.339	0.000
F34 Persistent mood [affective] disorders	0.661	0.339	0.000
M25.51 Pain in joint (Shoulder region)	0.661	0.339	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.660	0.339	0.000
M34.0 Progressive systemic sclerosis	0.660	0.339	0.000
M35 Other systemic involvement of connective tissue	0.660	0.340	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.660	0.340	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.660	0.340	0.000
T46.7 Peripheral vasodilators	0.660	0.340	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.660	0.340	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.660	0.340	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.660	0.340	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.660	0.340	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.660	0.340	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.659	0.341	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.659	0.341	0.000
W11 Fall on and from ladder	0.659	0.341	0.000
X45 Accidental poisoning by and exposure to alcohol	0.659	0.341	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.659	0.341	0.000
Y59 Other and unspecified vaccines and biological substances	0.658	0.342	0.000
Y58 Bacterial vaccines	0.658	0.342	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.658	0.342	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.658	0.342	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.658	0.342	0.000
S92.0 Fracture of calcaneus	0.657	0.343	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.656	0.344	0.000
R45.7 State of emotional shock and stress, unspecified	0.655	0.345	0.000
R45.6 Physical violence	0.655	0.345	0.000
R45.5 Hostility	0.655	0.345	0.000
R45.4 Irritability and anger	0.655	0.345	0.000
R45.3 Demoralisation and apathy	0.655	0.345	0.000
T92 Sequelae of injuries of upper limb	0.655	0.345	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.655	0.345	0.000
F10.8 Other mental and behavioural disorders	0.655	0.345	0.000
F10.7 Residual and late-onset psychotic disorder	0.655	0.345	0.000
M79.3 Panniculitis, unspecified	0.654	0.345	0.000
W17 Other fall from one level to another	0.654	0.346	0.000
Q00-Q07 Congenital malformations of the nervous system	0.654	0.346	0.000
M79.8 Other specified soft tissue disorders	0.654	0.346	0.000
M85.6 Other cyst of bone	0.654	0.346	0.000
D67 Hereditary factor IX deficiency	0.653	0.347	0.000
D66 Hereditary factor VIII deficiency	0.653	0.347	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.653	0.347	0.000
D83 Common variable immunodeficiency	0.653	0.347	0.000
M22 Disorders of patella	0.651	0.348	0.001
T94 Sequelae of injuries involving multiple and unspecified body regions	0.651	0.349	0.000
D69.5 Secondary thrombocytopenia	0.651	0.349	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.650	0.350	0.000
R41.1 Anterograde amnesia	0.650	0.350	0.000
T95 Sequelae of burns, corrosions and frostbite	0.650	0.350	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.650	0.350	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.650	0.350	0.000
W07.0 Home	0.650	0.350	0.000
T66-T78 Other and unspecified effects of external causes	0.650	0.350	0.000
W19 Unspecified fall	0.648	0.352	0.000
R47-R49 Symptoms and signs involving speech and voice	0.647	0.353	0.000
U89 Agent resistant to other and unspecified antibiotics	0.647	0.353	0.000
F44.5 Dissociative convulsions	0.646	0.354	0.000
M79.78 Fibromyalgia (Other)	0.646	0.354	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.646	0.354	0.000
M79.76 Fibromyalgia (Lower leg)	0.646	0.354	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.646	0.354	0.000
M79.74 Fibromyalgia (Hand)	0.646	0.354	0.000
M79.73 Fibromyalgia (Forearm)	0.646	0.354	0.000
M79.72 Fibromyalgia (Upper arm)	0.646	0.354	0.000
M79.71 Fibromyalgia (Shoulder region)	0.646	0.354	0.000
M25.9 Joint disorder, unspecified	0.645	0.354	0.000
M21.1 Varus deformity, not elsewhere classified	0.645	0.355	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.645	0.355	0.000
M21.6 Other acquired deformities of ankle and foot	0.645	0.355	0.000
F33.8 Other recurrent depressive disorders	0.642	0.358	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.642	0.358	0.000
R45.2 Unhappiness	0.642	0.358	0.000
D68.0 Von Willebrand's disease	0.642	0.358	0.000
F68 Other disorders of adult personality and behaviour	0.641	0.359	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.641	0.359	0.000
F65 Disorders of sexual preference	0.641	0.359	0.000
F63 Habit and impulse disorders	0.641	0.359	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.641	0.359	0.000
F61 Mixed and other personality disorders	0.641	0.359	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.640	0.360	0.000
W12 Fall on and from scaffolding	0.640	0.360	0.000
W09 Fall involving playground equipment	0.640	0.360	0.000
W04 Fall while being carried or supported by other persons	0.640	0.360	0.000
W00 Fall on same level involving ice and snow	0.640	0.360	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.639	0.361	0.000
S21.1 Open wound of front wall of thorax	0.639	0.361	0.000
Q64 Other congenital malformations of urinary system	0.638	0.361	0.000
M30 Polyarteritis nodosa and related conditions	0.638	0.362	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.638	0.362	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.638	0.362	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.638	0.362	0.000
X20-X29 Contact with venomous animals and plants	0.637	0.362	0.000
F30.0 Hypomania	0.637	0.363	0.000
W15 Fall from cliff	0.637	0.363	0.000
W05 Fall involving wheelchair	0.636	0.364	0.000
T93.2 Sequelae of other fractures of lower limb	0.636	0.364	0.000
Y00 Assault by blunt object	0.635	0.365	0.000
S13.5 Sprain and strain of thyroid region	0.635	0.365	0.000
S13.3 Multiple dislocations of neck	0.635	0.365	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.635	0.365	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.635	0.365	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.635	0.365	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.634	0.366	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.634	0.366	0.000
Q61.0 Congenital single renal cyst	0.634	0.366	0.000
Y45.1 Salicylates	0.634	0.366	0.000
F11.2 Dependence syndrome	0.633	0.366	0.000
S12.7 Multiple fractures of cervical spine	0.633	0.367	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.633	0.367	0.000
D68.9 Coagulation defect, unspecified	0.633	0.367	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.632	0.367	0.000
M83 Adult osteomalacia	0.632	0.368	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.631	0.369	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.631	0.369	0.000
F80 Specific developmental disorders of speech and language	0.631	0.369	0.000
S21.9 Open wound of thorax, part unspecified	0.631	0.369	0.000
Q82 Other congenital malformations of skin	0.630	0.370	0.000
R55 Syncope and collapse	0.630	0.370	0.000
Q50-Q56 Congenital malformations of genital organs	0.630	0.370	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.629	0.371	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.629	0.371	0.000
M89 Other disorders of bone	0.628	0.371	0.000
R54 Senility	0.628	0.371	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.628	0.372	0.000
R46.2 Strange and inexplicable behaviour	0.628	0.372	0.000
F30.8 Other manic episodes	0.628	0.372	0.000
F30.2 Mania with psychotic symptoms	0.628	0.372	0.000
F30.1 Mania without psychotic symptoms	0.628	0.372	0.000
M21.4 Flat foot [pes planus] (acquired)	0.628	0.372	0.000
S13.4 Sprain and strain of cervical spine	0.627	0.373	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.626	0.374	0.000
M85.0 Fibrous dysplasia (monostotic)	0.626	0.374	0.000
S19.7 Multiple injuries of neck	0.625	0.375	0.000
M40.56 Lordosis, unspecified (Lumbar region)	0.624	0.376	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.624	0.376	0.000
M84.4 Pathological fracture, not elsewhere classified	0.624	0.376	0.000
X48 Accidental poisoning by and exposure to pesticides	0.623	0.376	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.623	0.376	0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.623	0.376	0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.623	0.376	0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system	0.623	0.376	0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.623	0.376	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations