TreeWAS – Variant ID: rs77149735

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter VI Diseases of the nervous system	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
S00-S09 Injuries to the head	0.998	0.002
G40-G47 Episodic and paroxysmal disorders	0.997	0.003
G47 Sleep disorders	0.997	0.003
G47.3 Sleep apnoea	0.996	0.004
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.990	0.010
M05-M14 Inflammatory polyarthropathies	0.988	0.012
G35-G37 Demyelinating diseases of the central nervous system	0.978	0.022
M06 Other rheumatoid arthritis	0.969	0.031
Chapter V Mental and behavioural disorders	0.968	0.032
S02 Fracture of skull and facial bones	0.968	0.032
G35 Multiple sclerosis	0.955	0.045
M10 Gout	0.955	0.045
M06.9 Rheumatoid arthritis, unspecified	0.952	0.048
Chapter XXII Codes for special purposes	0.935	0.065
M10.9 Gout, unspecified	0.931	0.069
S00 Superficial injury of head	0.931	0.069
S02.4 Fracture of malar and maxillary bones	0.931	0.069
F30-F39 Mood [affective] disorders	0.928	0.072
Chapter X Diseases of the respiratory system	0.928	0.072
S01 Open wound of head	0.924	0.076
J09-J18 Influenza and pneumonia	0.923	0.077
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.922	0.078
M80-M85 Disorders of bone density and structure	0.920	0.080
Chapter VII Diseases of the eye and adnexa	0.912	0.088
M10.99 Gout, unspecified (Site unspecified)	0.904	0.096
S02.40 Fracture of malar and maxillary bones (closed)	0.904	0.096
J18 Pneumonia, organism unspecified	0.902	0.098
F00-F09 Organic, including symptomatic, mental disorders	0.900	0.100
J18.1 Lobar pneumonia, unspecified	0.889	0.111
G47.9 Sleep disorder, unspecified	0.888	0.112
G00-G09 Inflammatory diseases of the central nervous system	0.884	0.116
G30-G32 Other degenerative diseases of the nervous system	0.884	0.116
T20-T25 Burns and corrosions of external body surface, specified by site	0.879	0.121
S00.8 Superficial injury of other parts of head	0.876	0.124
M65-M68 Disorders of synovium and tendon	0.868	0.132
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.865	0.135
S20-S29 Injuries to the thorax	0.863	0.137
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.860	0.140
S40-S49 Injuries to the shoulder and upper arm	0.853	0.147
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.851	0.149
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.849	0.150
Chapter VIII Diseases of the ear and mastoid process	0.847	0.153
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.847	0.153
F33 Recurrent depressive disorder	0.841	0.159
H65-H75 Diseases of middle ear and mastoid	0.828	0.172
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.821	0.179
H50 Other strabismus	0.815	0.185
S01.9 Open wound of head, part unspecified	0.811	0.189
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.808	0.192
H53-H54 Visual disturbances and blindness	0.807	0.193
T36-T50 Poisoning by drugs, medicaments and biological substances	0.806	0.194
T66-T78 Other and unspecified effects of external causes	0.805	0.194
S01.3 Open wound of ear	0.805	0.195
F60-F69 Disorders of adult personality and behaviour	0.803	0.197
J80-J84 Other respiratory diseases principally affecting the interstitium	0.802	0.198
G37 Other demyelinating diseases of central nervous system	0.796	0.204
S50-S59 Injuries to the elbow and forearm	0.794	0.206
U80 Agent resistant to penicillin and related antibiotics	0.794	0.206
F03 Unspecified dementia	0.789	0.211
F34 Persistent mood [affective] disorders	0.786	0.214
G90-G99 Other disorders of the nervous system	0.785	0.215
F31 Bipolar affective disorder	0.782	0.218
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.779	0.221
M10.97 Gout, unspecified (Ankle and foot)	0.776	0.224
G30 Alzheimer's disease	0.775	0.225
M80 Osteoporosis with pathological fracture	0.775	0.225
M65 Synovitis and tenosynovitis	0.774	0.226
M60-M63 Disorders of muscles	0.770	0.230
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.769	0.231
M05 Seropositive rheumatoid arthritis	0.766	0.234
S06 Intracranial injury	0.765	0.235
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.765	0.235
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.763	0.237
H50.1 Divergent concomitant strabismus	0.763	0.237
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.760	0.240
J10 Influenza due to identified influenza virus	0.760	0.240
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.758	0.242
H66 Suppurative and unspecified otitis media	0.757	0.243
S01.0 Open wound of scalp	0.753	0.247
G47.1 Disorders of excessive somnolence [hypersomnias]	0.753	0.247
S02.3 Fracture of orbital floor	0.752	0.248
T79-T79 Certain early complications of trauma	0.752	0.248
M06.0 Seronegative rheumatoid arthritis	0.752	0.248
M84 Disorders of continuity of bone	0.749	0.251
S90-S99 Injuries to the ankle and foot	0.748	0.252
M81 Osteoporosis without pathological fracture	0.748	0.252
S10-S19 Injuries to the neck	0.748	0.252
F01 Vascular dementia	0.747	0.253
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.744	0.256
H65 Nonsuppurative otitis media	0.744	0.256
S00.9 Superficial injury of head, part unspecified	0.743	0.257
H53 Visual disturbances	0.742	0.258
S09 Other and unspecified injuries of head	0.741	0.259
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.739	0.261
T31 Burns classified according to extent of body surface involved	0.738	0.262
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.737	0.263
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.737	0.263
H00 Hordeolum and chalazion	0.735	0.265
T15-T19 Effects of foreign body entering through natural orifice	0.735	0.265
J17 Pneumonia in diseases classified elsewhere	0.734	0.265
M07 Psoriatic and enteropathic arthropathies	0.733	0.267
M13 Other arthritis	0.732	0.268
J13 Pneumonia due to Streptococcus pneumoniae	0.731	0.269
G63 Polyneuropathy in diseases classified elsewhere	0.730	0.270
M91-M94 Chondropathies	0.730	0.270
J11 Influenza, virus not identified	0.729	0.270
F00 Dementia in Alzheimer's disease	0.729	0.271
F33.9 Recurrent depressive disorder, unspecified	0.727	0.273
G80-G83 Cerebral palsy and other paralytic syndromes	0.727	0.273
S02.0 Fracture of vault of skull	0.726	0.274
S05 Injury of eye and orbit	0.725	0.275
M00-M03 Infectious arthropathies	0.722	0.277
S02.5 Fracture of tooth	0.721	0.278
S02.2 Fracture of nasal bones	0.721	0.279
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.721	0.279
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.720	0.280
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S51 Open wound of forearm	0.716	0.284
S08 Traumatic amputation of part of head	0.715	0.284
S07 Crushing injury of head	0.715	0.284
S04 Injury of cranial nerves	0.715	0.284
S03 Dislocation, sprain and strain of joints and ligaments of head	0.715	0.284
G46 Vascular syndromes of brain in cerebrovascular diseases	0.715	0.285
G41 Status epilepticus	0.715	0.285
G47.8 Other sleep disorders	0.715	0.285
G47.4 Narcolepsy and cataplexy	0.715	0.285
G47.2 Disorders of the sleep-wake schedule	0.715	0.285
H43-H45 Disorders of vitreous body and globe	0.711	0.289
J15 Bacterial pneumonia, not elsewhere classified	0.711	0.289
U80.1 Methicillin resistant agent	0.709	0.291
J18.0 Bronchopneumonia, unspecified	0.709	0.291
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.709	0.291
M14 Arthropathies in other diseases classified elsewhere	0.708	0.292
M12 Other specific arthropathies	0.708	0.292
M09 Juvenile arthritis in diseases classified elsewhere	0.708	0.292
M08 Juvenile arthritis	0.708	0.292
S42 Fracture of shoulder and upper arm	0.707	0.293
S02.1 Fracture of base of skull	0.707	0.293
S29 Other and unspecified injuries of thorax	0.706	0.294
H49 Paralytic strabismus	0.705	0.294
S70-S79 Injuries to the hip and thigh	0.703	0.297
S01.1 Open wound of eyelid and periocular area	0.703	0.297
T21 Burn and corrosion of trunk	0.702	0.298
G36 Other acute disseminated demyelination	0.701	0.299
G00 Bacterial meningitis, not elsewhere classified	0.699	0.300
T94 Sequelae of injuries involving multiple and unspecified body regions	0.698	0.302
S02.8 Fractures of other skull and facial bones	0.698	0.302
M06.8 Other specified rheumatoid arthritis	0.695	0.305
M06.4 Inflammatory polyarthropathy	0.695	0.305
M06.3 Rheumatoid nodule	0.695	0.305
M06.2 Rheumatoid bursitis	0.695	0.305
M06.1 Adult-onset Still's disease	0.695	0.305
H01 Other inflammation of eyelid	0.695	0.305
M85 Other disorders of bone density and structure	0.694	0.305
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.694	0.306
F70-F79 Mental retardation	0.694	0.306
H00.1 Chalazion	0.694	0.306
S02.9 Fracture of skull and facial bones, part unspecified	0.694	0.306
S02.7 Multiple fractures involving skull and facial bones	0.694	0.306
S00.7 Multiple superficial injuries of head	0.694	0.306
Chapter I Certain infectious and parasitic diseases	0.693	0.307
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.693	0.307
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.692	0.308
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.691	0.309
U51 Admission status on psychiatric patients	0.689	0.311
F33.1 Recurrent depressive disorder, current episode moderate	0.688	0.312
F80-F89 Disorders of psychological development	0.687	0.312
T23 Burn and corrosion of wrist and hand	0.687	0.312
J14 Pneumonia due to Haemophilus influenzae	0.687	0.313
G70-G73 Diseases of myoneural junction and muscle	0.686	0.313
H46-H48 Disorders of optic nerve and visual pathways	0.685	0.315
F60 Specific personality disorders	0.685	0.315
F99-F99 Unspecified mental disorder	0.685	0.315
H10-H13 Disorders of conjunctiva	0.684	0.315
F34.1 Dysthymia	0.684	0.315
M10.4 Other secondary gout	0.684	0.316
M10.3 Gout due to impairment of renal function	0.684	0.316
M10.2 Drug-induced gout	0.684	0.316
M10.1 Lead-induced gout	0.684	0.316
M10.0 Idiopathic gout	0.684	0.316
S01.5 Open wound of lip and oral cavity	0.683	0.317
M06.98 Rheumatoid arthritis, unspecified (Other)	0.683	0.317
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.683	0.317
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.683	0.317
M82 Osteoporosis in diseases classified elsewhere	0.682	0.318
H74 Other disorders of middle ear and mastoid	0.682	0.318
H53.4 Visual field defects	0.680	0.320
M15-M19 Arthrosis	0.679	0.321
J84 Other interstitial pulmonary diseases	0.679	0.321
S00.1 Contusion of eyelid and periocular area	0.678	0.322
S02.6 Fracture of mandible	0.677	0.323
Q60-Q64 Congenital malformations of the urinary system	0.676	0.324
T91 Sequelae of injuries of neck and trunk	0.676	0.324
Q38-Q45 Other congenital malformations of the digestive system	0.675	0.325
M65.9 Synovitis and tenosynovitis, unspecified	0.672	0.328
G03 Meningitis due to other and unspecified causes	0.671	0.329
Q80-Q89 Other congenital malformations	0.671	0.329
S49 Other and unspecified injuries of shoulder and upper arm	0.668	0.331
S00.2 Other superficial injuries of eyelid and periocular area	0.668	0.332
M10.98 Gout, unspecified (Other)	0.667	0.332
M10.95 Gout, unspecified (Pelvic region and thigh)	0.667	0.332
M10.94 Gout, unspecified (Hand)	0.667	0.332
M10.93 Gout, unspecified (Forearm)	0.667	0.332
M10.92 Gout, unspecified (Upper arm)	0.667	0.332
M10.91 Gout, unspecified (Shoulder region)	0.667	0.332
M10.90 Gout, unspecified (Multiple sites)	0.667	0.332
J60-J70 Lung diseases due to external agents	0.667	0.333
S00.5 Superficial injury of lip and oral cavity	0.667	0.333
S00.4 Superficial injury of ear	0.667	0.333
S02.41 Fracture of malar and maxillary bones (open)	0.667	0.333
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.666	0.334
H66.9 Otitis media, unspecified	0.666	0.334
F38 Other mood [affective] disorders	0.665	0.334
F30 Manic episode	0.665	0.334
F39 Unspecified mood [affective] disorder	0.665	0.334
S20 Superficial injury of thorax	0.665	0.334
G37.9 Demyelinating disease of central nervous system, unspecified	0.665	0.334
G44 Other headache syndromes	0.663	0.337
M11 Other crystal arthropathies	0.663	0.337
S01.7 Multiple open wounds of head	0.662	0.338
S01.4 Open wound of cheek and temporomandibular area	0.662	0.338
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.662	0.338
J12 Viral pneumonia, not elsewhere classified	0.662	0.338
J09 Influenza due to certain identified influenza virus	0.662	0.338
G30.9 Alzheimer's disease, unspecified	0.662	0.338
M83 Adult osteomalacia	0.660	0.340
T31.0 Burns involving less than 10% of body surface	0.660	0.340
Q50-Q56 Congenital malformations of genital organs	0.657	0.343
Chapter IV Endocrine, nutritional and metabolic diseases	0.656	0.344
G61 Inflammatory polyneuropathy	0.654	0.346
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.653	0.347
S22 Fracture of rib(s), sternum and thoracic spine	0.651	0.349
G95 Other diseases of spinal cord	0.650	0.350
S27 Injury of other and unspecified intrathoracic organs	0.648	0.352
M10.96 Gout, unspecified (Lower leg)	0.648	0.352
M80.9 Unspecified osteoporosis with pathological fracture	0.648	0.352
H72 Perforation of tympanic membrane	0.648	0.352
J18.8 Other pneumonia, organism unspecified	0.647	0.353
J18.2 Hypostatic pneumonia, unspecified	0.647	0.353
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.645	0.354
F02 Dementia in other diseases classified elsewhere	0.645	0.354
F09 Unspecified organic or symptomatic mental disorder	0.645	0.354
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.645	0.354
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.645	0.355
G63.2 Diabetic polyneuropathy	0.644	0.356
J00-J06 Acute upper respiratory infections	0.644	0.356
S40 Superficial injury of shoulder and upper arm	0.644	0.356
T78 Adverse effects, not elsewhere classified	0.644	0.356
S41 Open wound of shoulder and upper arm	0.643	0.356
M67 Other disorders of synovium and tendon	0.643	0.357
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.642	0.357
S01.2 Open wound of nose	0.641	0.359
H50.2 Vertical strabismus	0.640	0.360
J81 Pulmonary oedema	0.640	0.360
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.639	0.361
H66.3 Other chronic suppurative otitis media	0.639	0.361
U89 Agent resistant to other and unspecified antibiotics	0.639	0.361
F32 Depressive episode	0.639	0.361
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.638	0.362
H50.9 Strabismus, unspecified	0.638	0.362
F01.9 Vascular dementia, unspecified	0.638	0.362
M86-M90 Other osteopathies	0.637	0.363
G93 Other disorders of brain	0.635	0.365
H70 Mastoiditis and related conditions	0.634	0.366
G06 Intracranial and intraspinal abscess and granuloma	0.634	0.366
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.634	0.366
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.634	0.366
G09 Sequelae of inflammatory diseases of central nervous system	0.634	0.366
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.634	0.366
G01 Meningitis in bacterial diseases classified elsewhere	0.634	0.366
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.633	0.366
G45 Transient cerebral ischaemic attacks and related syndromes	0.633	0.367
U80.8 Agent resistant to other penicillin-related antibiotic	0.632	0.368
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.631	0.369
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.630	0.370
T25 Burn and corrosion of ankle and foot	0.630	0.370
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.630	0.370
T20 Burn and corrosion of head and neck	0.630	0.370
S00.3 Superficial injury of nose	0.629	0.371
S42.0 Fracture of clavicle	0.629	0.371
M65.3 Trigger finger	0.628	0.372
G40 Epilepsy	0.628	0.372
G30.0 Alzheimer's disease with early onset	0.624	0.376
H65.3 Chronic mucoid otitis media	0.624	0.376
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.623	0.377
M66 Spontaneous rupture of synovium and tendon	0.623	0.377
H55-H59 Other disorders of eye and adnexa	0.620	0.380
U81 Agent resistant to vancomycin and related antibiotics	0.620	0.380
U50 Level of care administered to neonates	0.620	0.380
U07 Emergency use of U07	0.620	0.380
U06 Emergency use of U06	0.620	0.380
U04 Severe acute respiratory syndrome [SARS]	0.620	0.380
U52 First in a series of a regular day/night admissions	0.620	0.380
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.619	0.381
S26 Injury of heart	0.619	0.381
S25 Injury of blood vessels of thorax	0.619	0.381
S24 Injury of nerves and spinal cord at thorax level	0.619	0.381
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.619	0.381
S21 Open wound of thorax	0.619	0.381
J95-J99 Other diseases of the respiratory system	0.619	0.381
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.618	0.381
Q20-Q28 Congenital malformations of the circulatory system	0.618	0.382
H50.0 Convergent concomitant strabismus	0.618	0.382
H65.2 Chronic serous otitis media	0.618	0.382
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.617	0.383
Q35-Q37 Cleft lip and cleft palate	0.617	0.383
Q30-Q34 Congenital malformations of the respiratory system	0.617	0.383
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.617	0.383
J40-J47 Chronic lower respiratory diseases	0.616	0.384
S06.6 Traumatic subarachnoid haemorrhage	0.614	0.386
M81.9 Osteoporosis, unspecified	0.613	0.387
M62 Other disorders of muscle	0.612	0.388
S48 Traumatic amputation of shoulder and upper arm	0.611	0.388
S46 Injury of muscle and tendon at shoulder and upper arm level	0.611	0.388
S45 Injury of blood vessels at shoulder and upper arm level	0.611	0.388
S44 Injury of nerves at shoulder and upper arm level	0.611	0.388
S47 Crushing injury of shoulder and upper arm	0.611	0.388
S56 Injury of muscle and tendon at forearm level	0.611	0.389
T94.1 Sequelae of injuries, not specified by body region	0.610	0.390
H51 Other disorders of binocular movement	0.610	0.390
H69 Other disorders of Eustachian tube	0.609	0.390
T68 Hypothermia	0.609	0.391
G60 Hereditary and idiopathic neuropathy	0.609	0.391
G64 Other disorders of peripheral nervous system	0.609	0.391
H53.0 Amblyopia ex anopsia	0.608	0.392
S51.9 Open wound of forearm, part unspecified	0.608	0.392
T32 Corrosions classified according to extent of body surface involved	0.607	0.392
T30 Burn and corrosion, body region unspecified	0.607	0.392
T29 Burns and corrosions of multiple body regions	0.607	0.392
U80.0 Penicillin resistant agent	0.607	0.393
F00.9 Dementia in Alzheimer's disease, unspecified	0.607	0.393
M05.9 Seropositive rheumatoid arthritis, unspecified	0.607	0.393
H73 Other disorders of tympanic membrane	0.606	0.394
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.606	0.394
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.605	0.395
E50-E64 Other nutritional deficiencies	0.604	0.396
F33.8 Other recurrent depressive disorders	0.603	0.397
F33.4 Recurrent depressive disorder, currently in remission	0.603	0.397
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.603	0.397
F33.0 Recurrent depressive disorder, current episode mild	0.603	0.397
M84.1 Nonunion of fracture [pseudarthrosis]	0.603	0.397
F31.9 Bipolar affective disorder, unspecified	0.601	0.398
H49.2 Sixth [abducent] nerve palsy	0.601	0.399
A00-A09 Intestinal infectious diseases	0.601	0.399
S00.0 Superficial injury of scalp	0.601	0.399
H53.2 Diplopia	0.601	0.399
J17.2 Pneumonia in mycoses	0.599	0.400
S02.30 Fracture of orbital floor (closed)	0.598	0.402
G11 Hereditary ataxia	0.597	0.403
T14 Injury of unspecified body region	0.597	0.403
G04 Encephalitis, myelitis and encephalomyelitis	0.597	0.403
H43 Disorders of vitreous body	0.596	0.404
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.594	0.406
H68 Eustachian salpingitis and obstruction	0.594	0.406
H67 Otitis media in diseases classified elsewhere	0.594	0.406
S29.9 Unspecified injury of thorax	0.593	0.407
Q00-Q07 Congenital malformations of the nervous system	0.591	0.409
J11.1 Influenza with other respiratory manifestations, virus not identified	0.591	0.409
T98 Sequelae of other and unspecified effects of external causes	0.589	0.411
T95 Sequelae of burns, corrosions and frostbite	0.589	0.411
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.589	0.411
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.589	0.411
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.588	0.412
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.586	0.414
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.586	0.414
S51.8 Open wound of other parts of forearm	0.584	0.416
H50.8 Other specified strabismus	0.584	0.416
H50.6 Mechanical strabismus	0.584	0.416
H50.5 Heterophoria	0.584	0.416
H50.4 Other and unspecified heterotropia	0.584	0.416
H50.3 Intermittent heterotropia	0.584	0.416
M84.4 Pathological fracture, not elsewhere classified	0.584	0.416
M80.0 Postmenopausal osteoporosis with pathological fracture	0.584	0.416
G62 Other polyneuropathies	0.583	0.416
M40-M43 Deforming dorsopathies	0.582	0.417
S90 Superficial injury of ankle and foot	0.580	0.420
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.579	0.421
H05 Disorders of orbit	0.579	0.421
H03 Disorders of eyelid in diseases classified elsewhere	0.579	0.421
H04 Disorders of lachrymal system	0.579	0.421
S50 Superficial injury of forearm	0.578	0.421
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.578	0.422
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.578	0.422
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.578	0.422
T46 Poisoning by agents primarily affecting the cardiovascular system	0.578	0.422
T41 Poisoning by anaesthetics and therapeutic gases	0.578	0.422
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.578	0.422
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.578	0.422
T36 Poisoning by systemic antibiotics	0.578	0.422
S09.8 Other specified injuries of head	0.578	0.422
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.578	0.422
T75 Effects of other external causes	0.578	0.422
T74 Maltreatment syndromes	0.578	0.422
T73 Effects of other deprivation	0.578	0.422
T70 Effects of air pressure and water pressure	0.578	0.422
T69 Other effects of reduced temperature	0.578	0.422
T67 Effects of heat and light	0.578	0.422
T71 Asphyxiation	0.578	0.422
T66 Unspecified effects of radiation	0.578	0.422
M13.0 Polyarthritis, unspecified	0.577	0.423
F68 Other disorders of adult personality and behaviour	0.576	0.424
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.576	0.424
F65 Disorders of sexual preference	0.576	0.424
F64 Gender identity disorders	0.576	0.424
F63 Habit and impulse disorders	0.576	0.424
F62 Enduring personality changes, not attributable to brain damage and disease	0.576	0.424
F69 Unspecified disorder of adult personality and behaviour	0.576	0.424
F61 Mixed and other personality disorders	0.576	0.424
T51 Toxic effect of alcohol	0.576	0.424
T21.2 Burn of second degree of trunk	0.576	0.424
G91 Hydrocephalus	0.576	0.424
J82 Pulmonary eosinophilia, not elsewhere classified	0.575	0.425
T79 Certain early complications of trauma, not elsewhere classified	0.575	0.425
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.575	0.425
S10 Superficial injury of neck	0.575	0.425
T92 Sequelae of injuries of upper limb	0.574	0.426
M18 Arthrosis of first carpometacarpal joint	0.574	0.426
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.574	0.426
S42.00 Fracture of clavicle (closed)	0.573	0.426
H01.0 Blepharitis	0.572	0.428
F31.0 Bipolar affective disorder, current episode hypomanic	0.572	0.428
F52 Sexual dysfunction, not caused by organic disorder or disease	0.572	0.428
J80 Adult respiratory distress syndrome	0.571	0.429
T91.1 Sequelae of fracture of spine	0.571	0.429
G37.8 Other specified demyelinating diseases of central nervous system	0.571	0.429
G37.5 Concentric sclerosis [Balo]	0.571	0.429
G37.4 Subacute necrotising myelitis	0.571	0.429
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.571	0.429
G37.2 Central pontine myelinolysis	0.571	0.429
G37.1 Central demyelination of corpus callosum	0.571	0.429
G37.0 Diffuse sclerosis	0.571	0.429
T39.0 Salicylates	0.570	0.430
S59 Other and unspecified injuries of forearm	0.569	0.431
S58 Traumatic amputation of forearm	0.569	0.431
S57 Crushing injury of forearm	0.569	0.431
S55 Injury of blood vessels at forearm level	0.569	0.431
S54 Injury of nerves at forearm level	0.569	0.431
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.569	0.431
G82 Paraplegia and tetraplegia	0.569	0.431
T90 Sequelae of injuries of head	0.569	0.431
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.568	0.431
F60.3 Emotionally unstable personality disorder	0.568	0.432
G00.1 Pneumococcal meningitis	0.567	0.433
J84.1 Other interstitial pulmonary diseases with fibrosis	0.566	0.434
H01.8 Other specified inflammation of eyelid	0.565	0.435
F34.9 Persistent mood [affective] disorder, unspecified	0.564	0.436
F34.8 Other persistent mood [affective] disorders	0.564	0.436
F34.0 Cyclothymia	0.564	0.436
U51.0 Not Previously admitted to a psyciatric hospital	0.563	0.436
G31.9 Degenerative disease of nervous system, unspecified	0.563	0.436
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.563	0.437
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.563	0.437
G94 Other disorders of brain in diseases classified elsewhere	0.563	0.437
G90 Disorders of autonomic nervous system	0.563	0.437
G98 Other disorders of nervous system, not elsewhere classified	0.563	0.437
G92 Toxic encephalopathy	0.563	0.437
J47 Bronchiectasis	0.562	0.438
H53.8 Other visual disturbances	0.561	0.439
S06.2 Diffuse brain injury	0.561	0.439
F31.8 Other bipolar affective disorders	0.560	0.439
F31.7 Bipolar affective disorder, currently in remission	0.560	0.439
F31.6 Bipolar affective disorder, current episode mixed	0.560	0.439
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.560	0.439
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.560	0.439
G50-G59 Nerve, nerve root and plexus disorders	0.559	0.441
J15.1 Pneumonia due to Pseudomonas	0.558	0.442
F05 Delirium, not induced by alcohol and other psychoactive substances	0.558	0.442
B35-B49 Mycoses	0.557	0.443
G93.4 Encephalopathy, unspecified	0.556	0.444
G30.8 Other Alzheimer's disease	0.556	0.444
G30.1 Alzheimer's disease with late onset	0.556	0.444
M80.8 Other osteoporosis with pathological fracture	0.555	0.444
M80.5 Idiopathic osteoporosis with pathological fracture	0.555	0.444
M80.4 Drug-induced osteoporosis with pathological fracture	0.555	0.444
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.555	0.444
M80.2 Osteoporosis of disuse with pathological fracture	0.555	0.444
H65.4 Other chronic nonsuppurative otitis media	0.555	0.444
M65.8 Other synovitis and tenosynovitis	0.555	0.445
M65.2 Calcific tendinitis	0.555	0.445
M65.1 Other infective (teno)synovitis	0.555	0.445
M65.0 Abscess of tendon sheath	0.555	0.445
M81.4 Drug-induced osteoporosis	0.554	0.446
S70 Superficial injury of hip and thigh	0.554	0.446
M85.0 Fibrous dysplasia (monostotic)	0.554	0.446
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.554	0.446
S51.0 Open wound of elbow	0.554	0.446
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.554	0.446
T63 Toxic effect of contact with venomous animals	0.553	0.447
M19 Other arthrosis	0.553	0.447
M65.4 Radial styloid tenosynovitis [de Quervain]	0.553	0.447
G95.9 Disease of spinal cord, unspecified	0.553	0.447
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.553	0.447
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.553	0.447

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations