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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77345130
log Bayes Factor = 9.73262
Chromosome 3   position 163,126,687  (GRCh37) Explore rs77345130 on Ensembl!
Variant rs77345130 is part of Cluster X0080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M75 Shoulder lesions
0.996 0.004 0.000
G90-G99 Other disorders of the nervous system
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.992 0.008 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.990 0.010 0.000
O60-O75 Complications of labour and delivery
0.989 0.011 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.985 0.015 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.983 0.017 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.977 0.023 0.000
M75.0 Adhesive capsulitis of shoulder
0.975 0.025 0.000
G81 Hemiplegia
0.973 0.027 0.000
M50-M54 Other dorsopathies
0.967 0.033 0.000
G81.9 Hemiplegia, unspecified
0.966 0.034 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.964 0.036 0.000
S90-S99 Injuries to the ankle and foot
0.963 0.037 0.000
F41 Other anxiety disorders
0.958 0.042 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.956 0.044 0.000
M75.4 Impingement syndrome of shoulder
0.947 0.053 0.000
F30-F39 Mood [affective] disorders
0.941 0.059 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.941 0.059 0.000
M80-M85 Disorders of bone density and structure
0.939 0.061 0.000
S20-S29 Injuries to the thorax
0.938 0.062 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.937 0.063 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.934 0.066 0.000
M77 Other enthesopathies
0.925 0.075 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.922 0.078 0.000
F41.9 Anxiety disorder, unspecified
0.920 0.080 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.914 0.086 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.911 0.089 0.000
M06.4 Inflammatory polyarthropathy
0.909 0.091 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.909 0.091 0.000
M45-M49 Spondylopathies
0.902 0.098 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.896 0.104 0.000
S92 Fracture of foot, except ankle
0.894 0.106 0.000
T66-T78 Other and unspecified effects of external causes
0.893 0.107 0.000
S20 Superficial injury of thorax
0.892 0.108 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.889 0.111 0.000
M06.0 Seronegative rheumatoid arthritis
0.883 0.117 0.000
M54 Dorsalgia
0.881 0.119 0.000
O72 Postpartum haemorrhage
0.880 0.120 0.000
O63 Long labour
0.876 0.124 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.873 0.127 0.000
M77.9 Enthesopathy, unspecified
0.873 0.127 0.000
M11 Other crystal arthropathies
0.871 0.129 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.870 0.130 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.868 0.132 0.000
F33 Recurrent depressive disorder
0.866 0.134 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.863 0.137 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.860 0.140 0.000
M75.1 Rotator cuff syndrome
0.860 0.140 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.857 0.143 0.000
M84 Disorders of continuity of bone
0.854 0.146 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.843 0.157 0.000
F80-F89 Disorders of psychological development
0.840 0.160 0.000
M45 Ankylosing spondylitis
0.837 0.163 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.837 0.163 0.000
Chapter I Certain infectious and parasitic diseases
0.834 0.166 0.000
S90 Superficial injury of ankle and foot
0.831 0.169 0.000
M50 Cervical disk disorders
0.831 0.169 0.000
M05 Seropositive rheumatoid arthritis
0.831 0.169 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.831 0.169 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.823 0.177 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.822 0.178 0.000
S10-S19 Injuries to the neck
0.817 0.183 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.817 0.183 0.000
M51 Other intervertebral disk disorders
0.815 0.185 0.000
G95 Other diseases of spinal cord
0.813 0.187 0.000
O63.0 Prolonged first stage (of labour)
0.813 0.187 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.812 0.188 0.000
M75.9 Shoulder lesion, unspecified
0.812 0.188 0.000
F32 Depressive episode
0.812 0.188 0.000
S60-S69 Injuries to the wrist and hand
0.810 0.190 0.000
M40-M43 Deforming dorsopathies
0.808 0.192 0.000
M54.6 Pain in thoracic spine
0.805 0.194 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.802 0.198 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.802 0.198 0.000
Chapter XXII Codes for special purposes
0.800 0.200 0.000
S92.0 Fracture of calcaneus
0.799 0.201 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.795 0.205 0.000
M50.0 Cervical disk disorder with myelopathy
0.795 0.205 0.000
F40 Phobic anxiety disorders
0.794 0.206 0.000
T78 Adverse effects, not elsewhere classified
0.791 0.209 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.789 0.211 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.788 0.212 0.000
F45 Somatoform disorders
0.788 0.212 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.787 0.213 0.000
T85.2 Mechanical complication of intraocular lens
0.786 0.214 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.785 0.215 0.000
G70-G73 Diseases of myoneural junction and muscle
0.784 0.216 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.784 0.216 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.783 0.217 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.781 0.219 0.000
M11.2 Other chondrocalcinosis
0.779 0.221 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.778 0.222 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.778 0.222 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.775 0.225 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.774 0.226 0.000
M85 Other disorders of bone density and structure
0.773 0.227 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.772 0.228 0.000
S70-S79 Injuries to the hip and thigh
0.770 0.230 0.000
G96 Other disorders of central nervous system
0.768 0.232 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.768 0.232 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.767 0.233 0.000
F33.9 Recurrent depressive disorder, unspecified
0.765 0.235 0.000
F41.2 Mixed anxiety and depressive disorder
0.762 0.238 0.000
O71 Other obstetric trauma
0.761 0.239 0.000
S62 Fracture at wrist and hand level
0.760 0.240 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.760 0.240 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.759 0.241 0.000
T86 Failure and rejection of transplanted organs and tissues
0.759 0.241 0.000
T87 Complications peculiar to reattachment and amputation
0.755 0.245 0.000
M00-M03 Infectious arthropathies
0.754 0.246 0.000
O62 Abnormalities of forces of labour
0.754 0.246 0.000
F41.1 Generalised anxiety disorder
0.754 0.246 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.752 0.248 0.000
F34 Persistent mood [affective] disorders
0.750 0.250 0.000
M65-M68 Disorders of synovium and tendon
0.749 0.251 0.000
S32 Fracture of lumbar spine and pelvis
0.748 0.252 0.000
O85-O92 Complications predominantly related to the puerperium
0.748 0.252 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.747 0.253 0.000
O72.0 Third-stage haemorrhage
0.746 0.254 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.745 0.255 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.744 0.256 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.742 0.258 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.740 0.260 0.000
O24 Diabetes mellitus in pregnancy
0.739 0.261 0.000
O75.8 Other specified complications of labour and delivery
0.737 0.263 0.000
M54.5 Low back pain
0.737 0.263 0.000
M14 Arthropathies in other diseases classified elsewhere
0.736 0.264 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.736 0.264 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.734 0.266 0.000
M79.7 Fibromyalgia
0.734 0.266 0.000
S99 Other and unspecified injuries of ankle and foot
0.732 0.268 0.000
S92.00 Fracture of calcaneus (closed)
0.732 0.268 0.000
O23 Infections of genito-urinary tract in pregnancy
0.730 0.269 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.730 0.270 0.000
G80 Infantile cerebral palsy
0.729 0.271 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.271 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.729 0.271 0.000
T92 Sequelae of injuries of upper limb
0.728 0.272 0.000
B35-B49 Mycoses
0.727 0.273 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.726 0.274 0.000
M60-M63 Disorders of muscles
0.725 0.275 0.000
G30-G32 Other degenerative diseases of the nervous system
0.724 0.276 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.723 0.277 0.000
O72.1 Other immediate postpartum haemorrhage
0.722 0.278 0.000
G82 Paraplegia and tetraplegia
0.721 0.279 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.3 Rheumatoid nodule
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.716 0.283 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.716 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
S92.3 Fracture of metatarsal bone
0.715 0.285 0.000
M75.8 Other shoulder lesions
0.714 0.285 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.714 0.286 0.000
G90 Disorders of autonomic nervous system
0.714 0.286 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.714 0.286 0.000
G92 Toxic encephalopathy
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.287 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.713 0.287 0.000
G40-G47 Episodic and paroxysmal disorders
0.713 0.287 0.000
M72 Fibroblastic disorders
0.712 0.288 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.711 0.288 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.711 0.288 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.711 0.289 0.000
O61 Failed induction of labour
0.711 0.289 0.000
O74 Complications of anaesthesia during labour and delivery
0.709 0.291 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.709 0.291 0.000
O60 Preterm delivery
0.709 0.291 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.709 0.291 0.000
Q60-Q64 Congenital malformations of the urinary system
0.709 0.291 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.708 0.292 0.000
M71 Other bursopathies
0.706 0.294 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.706 0.294 0.000
S80-S89 Injuries to the knee and lower leg
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.705 0.295 0.000
G91 Hydrocephalus
0.704 0.296 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.704 0.296 0.000
T68 Hypothermia
0.704 0.296 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.703 0.297 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.702 0.298 0.000
D50-D53 Nutritional anaemias
0.702 0.298 0.000
F80 Specific developmental disorders of speech and language
0.702 0.298 0.000
S29 Other and unspecified injuries of thorax
0.702 0.298 0.000
F48 Other neurotic disorders
0.701 0.299 0.000
F44 Dissociative [conversion] disorders
0.701 0.299 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.700 0.300 0.000
M80 Osteoporosis with pathological fracture
0.700 0.300 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.700 0.300 0.000
A30-A49 Other bacterial diseases
0.699 0.301 0.000
M53 Other dorsopathies, not elsewhere classified
0.698 0.302 0.000
G81.1 Spastic hemiplegia
0.698 0.302 0.000
G81.0 Flaccid hemiplegia
0.698 0.302 0.000
S70 Superficial injury of hip and thigh
0.698 0.302 0.000
T93 Sequelae of injuries of lower limb
0.698 0.302 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.697 0.303 0.000
M75.3 Calcific tendinitis of shoulder
0.695 0.305 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.694 0.306 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.692 0.308 0.000
M81 Osteoporosis without pathological fracture
0.692 0.308 0.000
S98 Traumatic amputation of ankle and foot
0.691 0.309 0.000
S97 Crushing injury of ankle and foot
0.691 0.309 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.691 0.309 0.000
S95 Injury of blood vessels at ankle and foot level
0.691 0.309 0.000
S94 Injury of nerves at ankle and foot level
0.691 0.309 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.690 0.310 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.688 0.312 0.000
M75.2 Bicipital tendinitis
0.688 0.312 0.000
S27 Injury of other and unspecified intrathoracic organs
0.688 0.312 0.000
Q80-Q89 Other congenital malformations
0.687 0.312 0.000
F41.8 Other specified anxiety disorders
0.687 0.313 0.000
F41.3 Other mixed anxiety disorders
0.687 0.313 0.000
M07 Psoriatic and enteropathic arthropathies
0.686 0.314 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.686 0.314 0.000
Q50-Q56 Congenital malformations of genital organs
0.685 0.315 0.000
S62.6 Fracture of other finger
0.684 0.316 0.000
T78.3 Angioneurotic oedema
0.684 0.316 0.000
S92.2 Fracture of other tarsal bone(s)
0.682 0.317 0.000
G95.9 Disease of spinal cord, unspecified
0.681 0.319 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.680 0.320 0.000
O20 Haemorrhage in early pregnancy
0.680 0.320 0.000
O75.0 Maternal distress during labour and delivery
0.679 0.321 0.000
M91-M94 Chondropathies
0.678 0.322 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.676 0.324 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.676 0.324 0.000
S31 Open wound of abdomen, lower back and pelvis
0.676 0.324 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
M77.4 Metatarsalgia
0.675 0.325 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.675 0.325 0.000
O63.9 Long labour, unspecified
0.675 0.325 0.000
F38 Other mood [affective] disorders
0.675 0.325 0.000
F30 Manic episode
0.675 0.325 0.000
F39 Unspecified mood [affective] disorder
0.675 0.325 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.674 0.325 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.674 0.325 0.000
T83.2 Mechanical complication of graft of urinary organ
0.674 0.325 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.674 0.326 0.000
M83 Adult osteomalacia
0.673 0.327 0.000
M82 Osteoporosis in diseases classified elsewhere
0.673 0.327 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.673 0.327 0.000
S26 Injury of heart
0.673 0.327 0.000
S25 Injury of blood vessels of thorax
0.673 0.327 0.000
S24 Injury of nerves and spinal cord at thorax level
0.673 0.327 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.673 0.327 0.000
S21 Open wound of thorax
0.673 0.327 0.000
M54.3 Sciatica
0.673 0.327 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.672 0.328 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.672 0.328 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.672 0.328 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.672 0.328 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.672 0.328 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
T36 Poisoning by systemic antibiotics
0.672 0.328 0.000
T91 Sequelae of injuries of neck and trunk
0.671 0.329 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
O80-O84 Delivery
0.669 0.331 0.000
M48 Other spondylopathies
0.669 0.331 0.000
O73 Retained placenta and membranes, without haemorrhage
0.668 0.332 0.000
M85.8 Other specified disorders of bone density and structure
0.668 0.332 0.000
M79.1 Myalgia
0.667 0.333 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.666 0.333 0.000
S92.1 Fracture of talus
0.666 0.334 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.666 0.334 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.335 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.664 0.336 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.664 0.336 0.000
M77.0 Medial epicondylitis
0.664 0.336 0.000
T40.6 Other and unspecified narcotics
0.663 0.337 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.663 0.337 0.000
M77.5 Other enthesopathy of foot
0.663 0.337 0.000
M77.3 Calcaneal spur
0.663 0.337 0.000
M77.2 Periarthritis of wrist
0.663 0.337 0.000
F32.9 Depressive episode, unspecified
0.663 0.337 0.000
M79.79 Fibromyalgia (Site unspecified)
0.663 0.337 0.000
F40.2 Specific (isolated) phobias
0.663 0.337 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.661 0.339 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.661 0.339 0.000
M54.1 Radiculopathy
0.661 0.339 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.661 0.339 0.000
G93 Other disorders of brain
0.660 0.340 0.000
M84.0 Malunion of fracture
0.660 0.340 0.000
S62.5 Fracture of thumb
0.658 0.342 0.000
S91 Open wound of ankle and foot
0.656 0.344 0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)
0.655 0.345 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.653 0.346 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.653 0.347 0.000
S64 Injury of nerves at wrist and hand level
0.653 0.347 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.652 0.348 0.000
F99-F99 Unspecified mental disorder
0.652 0.348 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.652 0.348 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.652 0.348 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.652 0.348 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.652 0.348 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.652 0.348 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.652 0.348 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.652 0.348 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.652 0.348 0.000
F45.8 Other somatoform disorders
0.652 0.348 0.000
F81 Specific developmental disorders of scholastic skills
0.650 0.350 0.000
D51 Vitamin B12 deficiency anaemia
0.647 0.353 0.000
S20.2 Contusion of thorax
0.647 0.353 0.000
F42 Obsessive-compulsive disorder
0.647 0.353 0.000
O21 Excessive vomiting in pregnancy
0.646 0.354 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.646 0.354 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.646 0.354 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.646 0.354 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.645 0.354 0.000
T40.2 Other opioids
0.645 0.355 0.000
B99-B99 Other infectious diseases
0.644 0.356 0.000
G70 Myasthenia gravis and other myoneural disorders
0.644 0.356 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.643 0.357 0.000
O62.0 Primary inadequate contractions
0.643 0.357 0.000
O29 Complications of anaesthesia during pregnancy
0.642 0.357 0.000
O28 Abnormal findings on antenatal screening of mother
0.642 0.357 0.000
O22 Venous complications in pregnancy
0.642 0.357 0.000
O25 Malnutrition in pregnancy
0.642 0.357 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.642 0.358 0.000
F43 Reaction to severe stress, and adjustment disorders
0.642 0.358 0.000
B15-B19 Viral hepatitis
0.641 0.358 0.000
M77.1 Lateral epicondylitis
0.641 0.359 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.641 0.359 0.000
S92.9 Fracture of foot, unspecified
0.641 0.359 0.000
S92.7 Multiple fractures of foot
0.641 0.359 0.000
S92.5 Fracture of other toe
0.641 0.359 0.000
S92.4 Fracture of great toe
0.641 0.359 0.000
T75 Effects of other external causes
0.640 0.360 0.000
T74 Maltreatment syndromes
0.640 0.360 0.000
T73 Effects of other deprivation
0.640 0.360 0.000
T70 Effects of air pressure and water pressure
0.640 0.360 0.000
T69 Other effects of reduced temperature
0.640 0.360 0.000
T67 Effects of heat and light
0.640 0.360 0.000
T71 Asphyxiation
0.640 0.360 0.000
T66 Unspecified effects of radiation
0.640 0.360 0.000
S10 Superficial injury of neck
0.640 0.360 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.640 0.360 0.000
S20.7 Multiple superficial injuries of thorax
0.639 0.361 0.000
S20.4 Other superficial injuries of back wall of thorax
0.639 0.361 0.000
S20.3 Other superficial injuries of front wall of thorax
0.639 0.361 0.000
S20.1 Other and unspecified superficial injuries of breast
0.639 0.361 0.000
S20.0 Contusion of breast
0.639 0.361 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.639 0.361 0.000
O66 Other obstructed labour
0.638 0.362 0.000
O75.9 Complication of labour and delivery, unspecified
0.637 0.363 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.637 0.363 0.000
O75.4 Other complications of obstetric surgery and procedures
0.637 0.363 0.000
O75.3 Other infection during labour
0.637 0.363 0.000
O75.1 Shock during or following labour and delivery
0.637 0.363 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.636 0.364 0.000
M43 Other deforming dorsopathies
0.634 0.366 0.000
G83 Other paralytic syndromes
0.634 0.366 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.633 0.367 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.633 0.367 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.633 0.367 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.633 0.367 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.633 0.367 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.633 0.367 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.633 0.367 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.633 0.367 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.633 0.367 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.633 0.367 0.000
B44 Aspergillosis
0.632 0.368 0.000
M54.8 Other dorsalgia
0.631 0.368 0.000
M54.0 Panniculitis affecting regions of neck and back
0.631 0.368 0.000
O72.3 Postpartum coagulation defects
0.631 0.369 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.631 0.369 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.631 0.369 0.000
T79-T79 Certain early complications of trauma
0.630 0.369 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.630 0.370 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.630 0.370 0.000
M86-M90 Other osteopathies
0.629 0.370 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.628 0.372 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.628 0.372 0.000
Q61 Cystic kidney disease
0.628 0.372 0.000
S50-S59 Injuries to the elbow and forearm
0.627 0.373 0.000
T98 Sequelae of other and unspecified effects of external causes
0.626 0.374 0.000
T95 Sequelae of burns, corrosions and frostbite
0.626 0.374 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.626 0.374 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.626 0.374 0.000
M77.99 Enthesopathy, unspecified (Site unspecified)
0.626 0.374 0.000
M77.98 Enthesopathy, unspecified (Other)
0.626 0.374 0.000
M77.96 Enthesopathy, unspecified (Lower leg)
0.626 0.374 0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)
0.626 0.374 0.000
M77.94 Enthesopathy, unspecified (Hand)
0.626 0.374 0.000
M77.93 Enthesopathy, unspecified (Forearm)
0.626 0.374 0.000
M77.92 Enthesopathy, unspecified (Upper arm)
0.626 0.374 0.000
M77.90 Enthesopathy, unspecified (Multiple sites)
0.626 0.374 0.000
S32.0 Fracture of lumbar vertebra
0.625 0.375 0.000
M11.9 Crystal arthropathy, unspecified
0.625 0.375 0.000
M11.8 Other specified crystal arthropathies
0.625 0.375 0.000
M11.1 Familial chondrocalcinosis
0.625 0.375 0.000
M11.0 Hydroxyapatite deposition disease
0.625 0.375 0.000
G95.0 Syringomyelia and syringobulbia
0.625 0.375 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.624 0.376 0.000
O69.8 Labour and delivery complicated by other cord complications
0.624 0.376 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.624 0.376 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.624 0.376 0.000
O69.3 Labour and delivery complicated by short cord
0.624 0.376 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.624 0.376 0.000
M47 Spondylosis
0.624 0.376 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.622 0.378 0.000
S37 Injury of urinary and pelvic organs
0.622 0.378 0.000
S36 Injury of intra-abdominal organs
0.622 0.378 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.622 0.378 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.622 0.378 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.622 0.378 0.000
M79.5 Residual foreign body in soft tissue
0.621 0.379 0.000
F33.8 Other recurrent depressive disorders
0.621 0.379 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.621 0.379 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.620 0.380 0.000
E50-E64 Other nutritional deficiencies
0.620 0.380 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.619 0.381 0.000
G35 Multiple sclerosis
0.619 0.381 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.619 0.381 0.000
Q35-Q37 Cleft lip and cleft palate
0.619 0.381 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.619 0.381 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.619 0.381 0.000
S19 Other and unspecified injuries of neck
0.617 0.383 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.616 0.384 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.616 0.384 0.000
T51 Toxic effect of alcohol
0.615 0.385 0.000
S32.4 Fracture of acetabulum
0.615 0.385 0.000
F34.1 Dysthymia
0.613 0.387 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.612 0.388 0.000
M84.9 Disorder of continuity of bone, unspecified
0.612 0.388 0.000
M84.8 Other disorders of continuity of bone
0.612 0.388 0.000
M84.4 Pathological fracture, not elsewhere classified
0.612 0.388 0.000
M84.3 Stress fracture, not elsewhere classified
0.612 0.388 0.000
M84.2 Delayed union of fracture
0.612 0.388 0.000
M54.59 Low back pain (Site unspecified)
0.612 0.388 0.000
M54.4 Lumbago with sciatica
0.611 0.388 0.000
F52.2 Failure of genital response
0.611 0.389 0.000
F29 Unspecified nonorganic psychosis
0.611 0.389 0.000
M40 Kyphosis and lordosis
0.610 0.390 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.609 0.391 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.609 0.391 0.000
T45.0 Antiallergic and antiemetic drugs
0.608 0.392 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.608 0.392 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.607 0.393 0.000
E00-E07 Disorders of thyroid gland
0.607 0.393 0.000
T87.6 Other and unspecified complications of amputation stump
0.605 0.395 0.000
S12 Fracture of neck
0.604 0.396 0.000
G96.0 Cerebrospinal fluid leak
0.604 0.396 0.000
E40-E46 Malnutrition
0.604 0.396 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.603 0.397 0.000
F80.1 Expressive language disorder
0.603 0.397 0.000
T56 Toxic effect of metals
0.602 0.397 0.000
F84 Pervasive developmental disorders
0.602 0.398 0.000
F89 Unspecified disorder of psychological development
0.602 0.398 0.000
F88 Other disorders of psychological development
0.602 0.398 0.000
F83 Mixed specific developmental disorders
0.602 0.398 0.000
F82 Specific developmental disorder of motor function
0.602 0.398 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.602 0.398 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.600 0.400 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.600 0.400 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.600 0.400 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.600 0.400 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.600 0.400 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.600 0.400 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.600 0.400 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.600 0.400 0.000
M50.2 Other cervical disk displacement
0.600 0.400 0.000
M54.2 Cervicalgia
0.599 0.400 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.599 0.401 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.599 0.401 0.000
M41 Scoliosis
0.599 0.401 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.598 0.402 0.000
B50-B64 Protozoal diseases
0.598 0.402 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.598 0.402 0.000
A75-A79 Rickettsioses
0.598 0.402 0.000
A70-A74 Other diseases caused by chlamydiae
0.598 0.402 0.000
A65-A69 Other spirochaetal diseases
0.598 0.402 0.000
A20-A28 Certain zoonotic bacterial diseases
0.598 0.402 0.000
A15-A19 Tuberculosis
0.598 0.402 0.000
O71.4 Obstetric high vaginal laceration alone
0.597 0.403 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.596 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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