TreeWAS – Variant ID: rs77367389

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter V Mental and behavioural disorders	0.999	0.001
F30-F39 Mood [affective] disorders	0.997	0.003
I60-I69 Cerebrovascular diseases	0.995	0.005
F32 Depressive episode	0.994	0.006
Chapter I Certain infectious and parasitic diseases	0.993	0.007
F32.9 Depressive episode, unspecified	0.988	0.012
A00-A09 Intestinal infectious diseases	0.984	0.016
R50-R69 General symptoms and signs	0.980	0.020
Chapter XI Diseases of the digestive system	0.977	0.023
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.972	0.028
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.971	0.029
I30-I52 Other forms of heart disease	0.969	0.031
Chapter XX External causes of morbidity and mortality	0.964	0.036
A09.9 Gastroenteritis and colitis of unspecified origin	0.963	0.037
Chapter IV Endocrine, nutritional and metabolic diseases	0.961	0.039
R30-R39 Symptoms and signs involving the urinary system	0.958	0.042
T36-T50 Poisoning by drugs, medicaments and biological substances	0.952	0.048
R31 Unspecified haematuria	0.952	0.048
I63 Cerebral infarction	0.949	0.051
S80-S89 Injuries to the knee and lower leg	0.944	0.056
K55-K64 Other diseases of intestines	0.942	0.058
S60-S69 Injuries to the wrist and hand	0.942	0.058
Chapter XV Pregnancy, childbirth and the puerperium	0.941	0.059
R56 Convulsions, not elsewhere classified	0.939	0.061
I64 Stroke, not specified as haemorrhage or infarction	0.937	0.063
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.936	0.064
Chapter XIV Diseases of the genitourinary system	0.931	0.069
Chapter XII Diseases of the skin and subcutaneous tissue	0.927	0.073
I10-I15 Hypertensive diseases	0.926	0.074
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.925	0.075
K63 Other diseases of intestine	0.916	0.084
I69 Sequelae of cerebrovascular disease	0.910	0.090
R56.8 Other and unspecified convulsions	0.909	0.091
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.908	0.092
S00-S09 Injuries to the head	0.905	0.095
K63.5 Polyp of colon	0.905	0.095
R47-R49 Symptoms and signs involving speech and voice	0.902	0.098
S40-S49 Injuries to the shoulder and upper arm	0.901	0.099
K70-K77 Diseases of liver	0.898	0.102
T93 Sequelae of injuries of lower limb	0.897	0.102
F40-F48 Neurotic, stress-related and somatoform disorders	0.883	0.117
L60-L75 Disorders of skin appendages	0.879	0.121
F80-F89 Disorders of psychological development	0.869	0.131
S00 Superficial injury of head	0.869	0.131
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.866	0.134
I12 Hypertensive renal disease	0.866	0.134
I46 Cardiac arrest	0.865	0.135
O60-O75 Complications of labour and delivery	0.863	0.137
N10-N16 Renal tubulo-interstitial diseases	0.861	0.139
I63.9 Cerebral infarction, unspecified	0.861	0.139
E10-E14 Diabetes mellitus	0.856	0.144
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.854	0.146
K59 Other functional intestinal disorders	0.854	0.146
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.853	0.147
I05-I09 Chronic rheumatic heart diseases	0.849	0.151
S80 Superficial injury of lower leg	0.848	0.152
N40-N51 Diseases of male genital organs	0.848	0.152
T90 Sequelae of injuries of head	0.847	0.153
R79 Other abnormal findings of blood chemistry	0.842	0.158
L60 Nail disorders	0.837	0.163
K58 Irritable bowel syndrome	0.837	0.163
I50 Heart failure	0.837	0.163
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.836	0.164
I42 Cardiomyopathy	0.833	0.167
T15-T19 Effects of foreign body entering through natural orifice	0.833	0.167
O00-O08 Pregnancy with abortive outcome	0.828	0.172
R63 Symptoms and signs concerning food and fluid intake	0.826	0.174
L40-L45 Papulosquamous disorders	0.824	0.176
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.823	0.177
T93.2 Sequelae of other fractures of lower limb	0.822	0.177
F32.1 Moderate depressive episode	0.822	0.178
I45 Other conduction disorders	0.822	0.178
R52 Pain, not elsewhere classified	0.822	0.178
S82 Fracture of lower leg, including ankle	0.821	0.179
I20-I25 Ischaemic heart diseases	0.821	0.179
E65-E68 Obesity and other hyperalimentation	0.821	0.179
R51 Headache	0.820	0.180
R47 Speech disturbances, not elsewhere classified	0.820	0.180
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.819	0.181
E14 Unspecified diabetes mellitus	0.816	0.184
N13 Obstructive and reflux uropathy	0.813	0.187
N60-N64 Disorders of breast	0.809	0.191
I69.3 Sequelae of cerebral infarction	0.809	0.191
R25 Abnormal involuntary movements	0.808	0.192
L60.0 Ingrowing nail	0.807	0.193
I33 Acute and subacute endocarditis	0.806	0.194
I12.0 Hypertensive renal disease with renal failure	0.806	0.194
F33 Recurrent depressive disorder	0.803	0.197
I44 Atrioventricular and left bundle-branch block	0.801	0.199
S00.8 Superficial injury of other parts of head	0.800	0.200
I62 Other nontraumatic intracranial haemorrhage	0.800	0.200
R72 Abnormality of white blood cells, not elsewhere classified	0.799	0.201
B20-B24 Human immunodeficiency virus [HIV] disease	0.799	0.201
S42 Fracture of shoulder and upper arm	0.797	0.203
T92 Sequelae of injuries of upper limb	0.795	0.205
N17-N19 Renal failure	0.795	0.205
E14.9 Without complications	0.793	0.207
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.792	0.208
A08 Viral and other specified intestinal infections	0.792	0.208
F32.3 Severe depressive episode with psychotic symptoms	0.791	0.209
T43.2 Other and unspecified antidepressants	0.791	0.209
E70-E90 Metabolic disorders	0.790	0.210
I70-I79 Diseases of arteries, arterioles and capillaries	0.789	0.211
F00-F09 Organic, including symptomatic, mental disorders	0.788	0.212
A04 Other bacterial intestinal infections	0.787	0.213
K20-K31 Diseases of oesophagus, stomach and duodenum	0.787	0.213
R79.8 Other specified abnormal findings of blood chemistry	0.787	0.213
S00.9 Superficial injury of head, part unspecified	0.786	0.214
B95-B98 Bacterial, viral and other infectious agents	0.786	0.214
I38 Endocarditis, valve unspecified	0.785	0.215
I46.9 Cardiac arrest, unspecified	0.784	0.216
F32.2 Severe depressive episode without psychotic symptoms	0.783	0.217
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.783	0.217
I20 Angina pectoris	0.781	0.219
I51 Complications and ill-defined descriptions of heart disease	0.781	0.219
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.779	0.220
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.777	0.223
R59 Enlarged lymph nodes	0.777	0.223
F81 Specific developmental disorders of scholastic skills	0.776	0.224
S65 Injury of blood vessels at wrist and hand level	0.775	0.225
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.773	0.227
R19 Other symptoms and signs involving the digestive system and abdomen	0.773	0.227
O72 Postpartum haemorrhage	0.773	0.227
K76 Other diseases of liver	0.772	0.228
S64 Injury of nerves at wrist and hand level	0.772	0.228
F41 Other anxiety disorders	0.772	0.228
R87 Abnormal findings in specimens from female genital organs	0.771	0.229
O03 Spontaneous abortion	0.770	0.230
O94-O99 Other obstetric conditions, not elsewhere classified	0.770	0.230
X60-X84 Intentional self-harm	0.769	0.231
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.766	0.234
M50-M54 Other dorsopathies	0.766	0.234
E87 Other disorders of fluid, electrolyte and acid-base balance	0.766	0.234
R19.4 Change in bowel habit	0.765	0.235
L40 Psoriasis	0.763	0.237
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.762	0.238
I63.8 Other cerebral infarction	0.762	0.238
K75 Other inflammatory liver diseases	0.761	0.239
K13 Other diseases of lip and oral mucosa	0.760	0.240
I67 Other cerebrovascular diseases	0.758	0.242
K55 Vascular disorders of intestine	0.757	0.243
K08 Other disorders of teeth and supporting structures	0.755	0.244
K14 Diseases of tongue	0.754	0.246
R77 Other abnormalities of plasma proteins	0.754	0.246
Chapter VI Diseases of the nervous system	0.754	0.246
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.753	0.247
I20.9 Angina pectoris, unspecified	0.752	0.248
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.752	0.248
M05-M14 Inflammatory polyarthropathies	0.751	0.249
S20-S29 Injuries to the thorax	0.751	0.249
T42.4 Benzodiazepines	0.750	0.250
F31 Bipolar affective disorder	0.748	0.252
S61 Open wound of wrist and hand	0.748	0.252
E87.6 Hypokalaemia	0.746	0.254
K30 Dyspepsia	0.744	0.256
V20-V29 Motorcycle rider injured in transport accident	0.743	0.257
E50-E64 Other nutritional deficiencies	0.743	0.257
N13.3 Other and unspecified hydronephrosis	0.742	0.258
O20-O29 Other maternal disorders predominantly related to pregnancy	0.741	0.259
E20-E35 Disorders of other endocrine glands	0.741	0.259
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.741	0.259
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.741	0.259
K90-K93 Other diseases of the digestive system	0.740	0.260
W20-W49 Exposure to inanimate mechanical forces	0.739	0.261
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.738	0.262
S80.9 Superficial injury of lower leg, unspecified	0.737	0.263
S70-S79 Injuries to the hip and thigh	0.737	0.263
R61 Hyperhidrosis	0.736	0.264
M51 Other intervertebral disk disorders	0.736	0.264
F60-F69 Disorders of adult personality and behaviour	0.736	0.264
I95-I99 Other and unspecified disorders of the circulatory system	0.734	0.266
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.733	0.266
A80-A89 Viral infections of the central nervous system	0.733	0.267
K59.0 Constipation	0.732	0.268
Chapter XXII Codes for special purposes	0.732	0.268
K05 Gingivitis and periodontal diseases	0.731	0.269
R27 Other lack of coordination	0.730	0.270
S62 Fracture at wrist and hand level	0.729	0.271
K11 Diseases of salivary glands	0.727	0.273
S90-S99 Injuries to the ankle and foot	0.727	0.273
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.726	0.274
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.726	0.274
A30-A49 Other bacterial diseases	0.722	0.277
R50 Fever of unknown origin	0.722	0.278
K59.8 Other specified functional intestinal disorders	0.722	0.278
R68 Other general symptoms and signs	0.722	0.278
E66 Obesity	0.721	0.279
N45 Orchitis and epididymitis	0.720	0.280
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.720	0.280
F41.9 Anxiety disorder, unspecified	0.720	0.280
K58.9 Irritable bowel syndrome without diarrhoea	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
Chapter VIII Diseases of the ear and mastoid process	0.716	0.284
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.716	0.284
L40.5 Arthropathic psoriasis	0.716	0.284
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.715	0.285
F99-F99 Unspecified mental disorder	0.715	0.285
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.715	0.285
F38 Other mood [affective] disorders	0.714	0.285
F34 Persistent mood [affective] disorders	0.714	0.285
F30 Manic episode	0.714	0.285
F39 Unspecified mood [affective] disorder	0.714	0.285
X40-X49 Accidental poisoning by and exposure to noxious substances	0.714	0.285
V10-V19 Pedal cyclist injured in transport accident	0.714	0.286
S82.3 Fracture of lower end of tibia	0.714	0.286
I68 Cerebrovascular disorders in diseases classified elsewhere	0.713	0.286
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.713	0.286
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.713	0.287
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.713	0.287
N41 Inflammatory diseases of prostate	0.713	0.287
F32.8 Other depressive episodes	0.712	0.287
F32.0 Mild depressive episode	0.712	0.287
K29 Gastritis and duodenitis	0.712	0.288
R47.8 Other and unspecified speech disturbances	0.712	0.288
B99-B99 Other infectious diseases	0.712	0.288
B90-B94 Sequelae of infectious and parasitic diseases	0.712	0.288
B85-B89 Pediculosis, acariasis and other infestations	0.712	0.288
B65-B83 Helminthiases	0.712	0.288
B50-B64 Protozoal diseases	0.712	0.288
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.712	0.288
A75-A79 Rickettsioses	0.712	0.288
A70-A74 Other diseases caused by chlamydiae	0.712	0.288
A65-A69 Other spirochaetal diseases	0.712	0.288
A20-A28 Certain zoonotic bacterial diseases	0.712	0.288
A15-A19 Tuberculosis	0.712	0.288
S00.7 Multiple superficial injuries of head	0.712	0.288
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.712	0.288
M51.2 Other specified intervertebral disk displacement	0.711	0.289
F81.9 Developmental disorder of scholastic skills, unspecified	0.709	0.291
S60 Superficial injury of wrist and hand	0.708	0.292
A50-A64 Infections with a predominantly sexual mode of transmission	0.708	0.292
O72.1 Other immediate postpartum haemorrhage	0.708	0.292
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.708	0.292
T79-T79 Certain early complications of trauma	0.707	0.293
K02 Dental caries	0.707	0.293
N64 Other disorders of breast	0.707	0.293
Y51 Drugs primarily affecting the autonomic nervous system	0.707	0.293
O03.4 Incomplete, without complication	0.706	0.293
I45.1 Other and unspecified right bundle-branch block	0.706	0.294
I08 Multiple valve diseases	0.706	0.294
A07 Other protozoal intestinal diseases	0.706	0.294
A06 Amoebiasis	0.706	0.294
A05 Other bacterial foodborne intoxications	0.706	0.294
A03 Shigellosis	0.706	0.294
A02 Other Salmonella infections	0.706	0.294
A01 Typhoid and paratyphoid fevers	0.706	0.294
A00 Cholera	0.706	0.294
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.704	0.296
T18 Foreign body in alimentary tract	0.702	0.298
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.702	0.298
R62 Lack of expected normal physiological development	0.702	0.298
R57 Shock, not elsewhere classified	0.702	0.298
R64 Cachexia	0.702	0.298
R58 Haemorrhage, not elsewhere classified	0.702	0.298
R87.6 Abnormal cytological findings	0.702	0.298
K07 Dentofacial anomalies [including malocclusion]	0.702	0.298
B15-B19 Viral hepatitis	0.700	0.300
L50-L54 Urticaria and erythema	0.699	0.301
N17 Acute renal failure	0.698	0.302
T66-T78 Other and unspecified effects of external causes	0.698	0.302
O69 Labour and delivery complicated by umbilical cord complications	0.697	0.303
I10 Essential (primary) hypertension	0.697	0.303
T98 Sequelae of other and unspecified effects of external causes	0.696	0.304
T95 Sequelae of burns, corrosions and frostbite	0.696	0.304
T94 Sequelae of injuries involving multiple and unspecified body regions	0.696	0.304
T91 Sequelae of injuries of neck and trunk	0.696	0.304
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.696	0.304
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.696	0.304
L71 Rosacea	0.696	0.304
F43 Reaction to severe stress, and adjustment disorders	0.695	0.305
R33 Retention of urine	0.695	0.305
I52 Other heart disorders in diseases classified elsewhere	0.695	0.305
I48 Atrial fibrillation and flutter	0.695	0.305
I43 Cardiomyopathy in diseases classified elsewhere	0.695	0.305
I41 Myocarditis in diseases classified elsewhere	0.695	0.305
I40 Acute myocarditis	0.695	0.305
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.695	0.305
I37 Pulmonary valve disorders	0.695	0.305
I36 Nonrheumatic tricuspid valve disorders	0.695	0.305
I32 Pericarditis in diseases classified elsewhere	0.695	0.305
I30 Acute pericarditis	0.695	0.305
K63.1 Perforation of intestine (nontraumatic)	0.695	0.305
N00-N08 Glomerular diseases	0.695	0.305
N99-N99 Other disorders of the genitourinary system	0.695	0.305
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.694	0.306
S42.2 Fracture of upper end of humerus	0.694	0.306
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.693	0.307
R47.0 Dysphasia and aphasia	0.693	0.307
I42.0 Dilated cardiomyopathy	0.693	0.307
I50.9 Heart failure, unspecified	0.692	0.308
R25.8 Other and unspecified abnormal involuntary movements	0.692	0.308
R52.2 Other chronic pain	0.692	0.308
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.691	0.309
Y35-Y36 Legal intervention and operations of war	0.691	0.309
Y10-Y34 Event of undetermined intent	0.691	0.309
Y00-Y09 Assault	0.691	0.309
X85-X99 Assault	0.691	0.309
X58-X59 Accidental exposure to other and unspecified factors	0.691	0.309
X50-X57 Overexertion, travel and privation	0.691	0.309
X30-X39 Exposure to forces of nature	0.691	0.309
X20-X29 Contact with venomous animals and plants	0.691	0.309
X10-X19 Contact with heat and hot substances	0.691	0.309
X00-X09 Exposure to smoke, fire and flames	0.691	0.309
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.691	0.309
W75-W84 Other accidental threats to breathing	0.691	0.309
W65-W74 Accidental drowning and submersion	0.691	0.309
W50-W64 Exposure to animate mechanical forces	0.691	0.309
V98-V99 Other and unspecified transport accidents	0.691	0.309
V95-V97 Air and space transport accidents	0.691	0.309
V90-V94 Water transport accidents	0.691	0.309
V80-V89 Other land transport accidents	0.691	0.309
V70-V79 Bus occupant injured in transport accident	0.691	0.309
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.691	0.309
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.691	0.309
V40-V49 Car occupant injured in transport accident	0.691	0.309
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.691	0.309
V01-V09 Pedestrian injured in transport accident	0.691	0.309
I33.0 Acute and subacute infective endocarditis	0.689	0.311
E40-E46 Malnutrition	0.689	0.311
I12.9 Hypertensive renal disease without renal failure	0.689	0.311
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.687	0.313
R36 Urethral discharge	0.687	0.313
R34 Anuria and oliguria	0.687	0.313
T90.5 Sequelae of intracranial injury	0.686	0.314
S66 Injury of muscle and tendon at wrist and hand level	0.686	0.314
K58.0 Irritable bowel syndrome with diarrhoea	0.685	0.315
R49 Voice disturbances	0.685	0.315
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.684	0.316
N48 Other disorders of penis	0.684	0.316
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.683	0.317
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.683	0.317
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.683	0.317
T46 Poisoning by agents primarily affecting the cardiovascular system	0.683	0.317
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.683	0.317
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.683	0.317
T41 Poisoning by anaesthetics and therapeutic gases	0.683	0.317
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.683	0.317
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.683	0.317
T36 Poisoning by systemic antibiotics	0.683	0.317
R26 Abnormalities of gait and mobility	0.682	0.318
S81 Open wound of lower leg	0.682	0.318
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.681	0.319
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.681	0.319
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.681	0.319
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.681	0.319
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.681	0.319
K63.3 Ulcer of intestine	0.680	0.320
K09 Cysts of oral region, not elsewhere classified	0.679	0.321
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.679	0.321
I61 Intracerebral haemorrhage	0.677	0.323
T90.2 Sequelae of fracture of skull and facial bones	0.677	0.323
S89 Other and unspecified injuries of lower leg	0.677	0.323
S88 Traumatic amputation of lower leg	0.677	0.323
S87 Crushing injury of lower leg	0.677	0.323
S86 Injury of muscle and tendon at lower leg level	0.677	0.323
S85 Injury of blood vessels at lower leg level	0.677	0.323
S84 Injury of nerves at lower leg level	0.677	0.323
M91-M94 Chondropathies	0.676	0.324
K64 Haemorrhoids and perianal venous thrombosis	0.676	0.324
S69 Other and unspecified injuries of wrist and hand	0.676	0.324
S67 Crushing injury of wrist and hand	0.676	0.324
K01 Embedded and impacted teeth	0.675	0.325
O85-O92 Complications predominantly related to the puerperium	0.675	0.325
S68 Traumatic amputation of wrist and hand	0.674	0.326
R63.4 Abnormal weight loss	0.674	0.326
K10 Other diseases of jaws	0.674	0.326
R25.2 Cramp and spasm	0.673	0.327
R56.0 Febrile convulsions	0.673	0.327
I44.0 Atrioventricular block, first degree	0.673	0.327
S80.1 Contusion of other and unspecified parts of lower leg	0.673	0.327
O73 Retained placenta and membranes, without haemorrhage	0.672	0.328
Y52 Agents primarily affecting the cardiovascular system	0.672	0.328
R78 Findings of drugs and other substances, not normally found in blood	0.671	0.329
R76 Other abnormal immunological findings in serum	0.671	0.329
R74 Abnormal serum enzyme levels	0.671	0.329
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.671	0.329
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.671	0.329
R71 Abnormality of red blood cells	0.671	0.329
K61 Abscess of anal and rectal regions	0.669	0.331
T92.9 Sequelae of unspecified injury of upper limb	0.668	0.331
R53 Malaise and fatigue	0.668	0.332
I49 Other cardiac arrhythmias	0.668	0.332
I07 Rheumatic tricuspid valve diseases	0.667	0.333
K63.9 Disease of intestine, unspecified	0.665	0.335
O63 Long labour	0.665	0.335
L10-L14 Bullous disorders	0.665	0.335
F33.9 Recurrent depressive disorder, unspecified	0.665	0.335
F45 Somatoform disorders	0.664	0.335
K35-K38 Diseases of appendix	0.664	0.336
I51.7 Cardiomegaly	0.664	0.336
I15 Secondary hypertension	0.664	0.336
I13 Hypertensive heart and renal disease	0.664	0.336
I11 Hypertensive heart disease	0.664	0.336
N13.4 Hydroureter	0.663	0.337
K12 Stomatitis and related lesions	0.663	0.337
K06 Other disorders of gingiva and edentulous alveolar ridge	0.663	0.337
K03 Other diseases of hard tissues of teeth	0.663	0.337
K00 Disorders of tooth development and eruption	0.663	0.337
K75.8 Other specified inflammatory liver diseases	0.663	0.337
S64.3 Injury of digital nerve of thumb	0.663	0.337
T90.9 Sequelae of unspecified injury of head	0.662	0.337
I44.6 Other and unspecified fascicular block	0.662	0.338
Y83.6 Removal of other organ (partial) (total)	0.661	0.339
R63.0 Anorexia	0.661	0.339
I24 Other acute ischaemic heart diseases	0.660	0.340
R55 Syncope and collapse	0.660	0.340
B24 Unspecified human immunodeficiency virus [HIV] disease	0.660	0.340
N47 Redundant prepuce, phimosis and paraphimosis	0.660	0.340
K70 Alcoholic liver disease	0.659	0.340
F05 Delirium, not induced by alcohol and other psychoactive substances	0.659	0.341
K72 Hepatic failure, not elsewhere classified	0.658	0.342
O64 Obstructed labour due to malposition and malpresentation of foetus	0.657	0.342
K63.4 Enteroptosis	0.657	0.343
K63.2 Fistula of intestine	0.657	0.343
K63.0 Abscess of intestine	0.657	0.343
S82.1 Fracture of upper end of tibia	0.657	0.343
K29.5 Chronic gastritis, unspecified	0.656	0.344
K74 Fibrosis and cirrhosis of liver	0.655	0.344
N61 Inflammatory disorders of breast	0.655	0.345
S65.0 Injury of ulnar artery at wrist and hand level	0.654	0.346
A08.4 Viral intestinal infection, unspecified	0.654	0.346
B35-B49 Mycoses	0.654	0.346
R39 Other symptoms and signs involving the urinary system	0.654	0.346
K13.7 Other and unspecified lesions of oral mucosa	0.653	0.347
I50.1 Left ventricular failure	0.653	0.347
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.652	0.348
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.652	0.348
I69.1 Sequelae of intracerebral haemorrhage	0.652	0.348
I69.0 Sequelae of subarachnoid haemorrhage	0.652	0.348
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.651	0.349
I72 Other aneurysm	0.650	0.350
R10 Abdominal and pelvic pain	0.650	0.350
M80-M85 Disorders of bone density and structure	0.649	0.351
S08 Traumatic amputation of part of head	0.649	0.351
S07 Crushing injury of head	0.649	0.351
S06 Intracranial injury	0.649	0.351
S05 Injury of eye and orbit	0.649	0.351
S04 Injury of cranial nerves	0.649	0.351
S03 Dislocation, sprain and strain of joints and ligaments of head	0.649	0.351
K55.2 Angiodysplasia of colon	0.649	0.351
N13.9 Obstructive and reflux uropathy, unspecified	0.648	0.352
S80.8 Other superficial injuries of lower leg	0.647	0.353
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.647	0.353
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.647	0.353
S49 Other and unspecified injuries of shoulder and upper arm	0.646	0.354
S48 Traumatic amputation of shoulder and upper arm	0.646	0.354
S46 Injury of muscle and tendon at shoulder and upper arm level	0.646	0.354
S45 Injury of blood vessels at shoulder and upper arm level	0.646	0.354
S44 Injury of nerves at shoulder and upper arm level	0.646	0.354
S41 Open wound of shoulder and upper arm	0.646	0.354
S40 Superficial injury of shoulder and upper arm	0.646	0.354
S47 Crushing injury of shoulder and upper arm	0.646	0.354
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.646	0.354
A04.8 Other specified bacterial intestinal infections	0.645	0.355
E87.7 Fluid overload	0.644	0.356
K77 Liver disorders in diseases classified elsewhere	0.644	0.356
K73 Chronic hepatitis, not elsewhere classified	0.644	0.356
K71 Toxic liver disease	0.644	0.356
T93.9 Sequelae of unspecified injury of lower limb	0.643	0.356
T93.8 Sequelae of other specified injuries of lower limb	0.643	0.356
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.643	0.356
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.643	0.356
T93.4 Sequelae of injury of nerve of lower limb	0.643	0.356
T93.1 Sequelae of fracture of femur	0.643	0.356
T93.0 Sequelae of open wound of lower limb	0.643	0.356
N70-N77 Inflammatory diseases of female pelvic organs	0.643	0.357
N41.1 Chronic prostatitis	0.643	0.357
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.643	0.357
S50-S59 Injuries to the elbow and forearm	0.642	0.358
I73 Other peripheral vascular diseases	0.641	0.359
W00-W19 Falls	0.641	0.359
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.640	0.360
I46.0 Cardiac arrest with successful resuscitation	0.640	0.360
I42.1 Obstructive hypertrophic cardiomyopathy	0.639	0.361
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.639	0.361
E66.8 Other obesity	0.639	0.361
I08.1 Disorders of both mitral and tricuspid valves	0.639	0.361
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.638	0.362
S82.30 Fracture of lower end of tibia (closed)	0.637	0.363
I50.0 Congestive heart failure	0.636	0.364
B25-B34 Other viral diseases	0.636	0.364
I51.8 Other ill-defined heart diseases	0.636	0.364
S42.4 Fracture of lower end of humerus	0.636	0.364
Y60-Y69 Misadventures to patients during surgical and medical care	0.635	0.365
M65-M68 Disorders of synovium and tendon	0.635	0.365
I42.9 Cardiomyopathy, unspecified	0.635	0.365

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations