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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77386029
log Bayes Factor = 19.4286
Chromosome 6   position 24,998,665  (GRCh37) Explore rs77386029 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
M17 Gonarthrosis [arthrosis of knee]
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
K90 Intestinal malabsorption
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.996 0.004 0.000
E05.9 Thyrotoxicosis, unspecified
0.994 0.006 0.000
M17.0 Primary gonarthrosis, bilateral
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.993 0.007 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
J45 Asthma
0.986 0.014 0.000
J44 Other chronic obstructive pulmonary disease
0.984 0.016 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
K80 Cholelithiasis
0.979 0.021 0.000
J45.9 Asthma, unspecified
0.979 0.021 0.000
E20-E35 Disorders of other endocrine glands
0.978 0.022 0.000
H30-H36 Disorders of choroid and retina
0.975 0.025 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.972 0.028 0.000
M06 Other rheumatoid arthritis
0.969 0.031 0.000
E10-E14 Diabetes mellitus
0.969 0.031 0.000
M17.9 Gonarthrosis, unspecified
0.968 0.032 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.968 0.032 0.000
H35 Other retinal disorders
0.964 0.036 0.000
M25 Other joint disorders, not elsewhere classified
0.961 0.039 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.956 0.044 0.000
E10 Insulin-dependent diabetes mellitus
0.956 0.044 0.000
M80-M85 Disorders of bone density and structure
0.955 0.045 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.954 0.046 0.000
M06.9 Rheumatoid arthritis, unspecified
0.952 0.048 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.942 0.058 0.000
S90-S99 Injuries to the ankle and foot
0.938 0.062 0.000
E27 Other disorders of adrenal gland
0.930 0.070 0.000
M18 Arthrosis of first carpometacarpal joint
0.926 0.074 0.000
D68 Other coagulation defects
0.925 0.075 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.924 0.076 0.000
K35-K38 Diseases of appendix
0.923 0.077 0.000
E10.9 Without complications
0.920 0.080 0.000
M25.7 Osteophyte
0.919 0.081 0.000
M80 Osteoporosis with pathological fracture
0.912 0.088 0.000
M35 Other systemic involvement of connective tissue
0.910 0.090 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.907 0.093 0.000
L40-L45 Papulosquamous disorders
0.903 0.097 0.000
J00-J06 Acute upper respiratory infections
0.893 0.107 0.000
K35 Acute appendicitis
0.893 0.107 0.000
H35.4 Peripheral retinal degeneration
0.891 0.109 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.891 0.109 0.000
J47 Bronchiectasis
0.890 0.110 0.000
H35.7 Separation of retinal layers
0.882 0.118 0.000
E10.3 With ophthalmic complications
0.879 0.121 0.000
L40 Psoriasis
0.879 0.121 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.878 0.122 0.000
E70-E90 Metabolic disorders
0.876 0.124 0.000
S20-S29 Injuries to the thorax
0.870 0.130 0.000
H35.8 Other specified retinal disorders
0.869 0.131 0.000
M24 Other specific joint derangements
0.866 0.134 0.000
J42 Unspecified chronic bronchitis
0.865 0.135 0.000
J95-J99 Other diseases of the respiratory system
0.864 0.136 0.000
M25.77 Osteophyte (Ankle and foot)
0.861 0.139 0.000
M65-M68 Disorders of synovium and tendon
0.859 0.141 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.858 0.142 0.000
D60-D64 Aplastic and other anaemias
0.857 0.143 0.000
E23 Hypofunction and other disorders of pituitary gland
0.856 0.143 0.000
M10 Gout
0.855 0.145 0.000
H33 Retinal detachments and breaks
0.854 0.146 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.854 0.146 0.000
D68.8 Other specified coagulation defects
0.851 0.149 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.850 0.150 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.843 0.157 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.843 0.157 0.000
K82 Other diseases of gallbladder
0.842 0.158 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.842 0.158 0.000
K35.9 Acute appendicitis, unspecified
0.841 0.159 0.000
S40-S49 Injuries to the shoulder and upper arm
0.841 0.159 0.000
J43 Emphysema
0.833 0.167 0.000
M07 Psoriatic and enteropathic arthropathies
0.832 0.168 0.000
E27.1 Primary adrenocortical insufficiency
0.831 0.169 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.831 0.169 0.000
M35.0 Sicca syndrome [Sjogren]
0.829 0.171 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.826 0.173 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.826 0.174 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.826 0.174 0.000
L40.9 Psoriasis, unspecified
0.826 0.174 0.000
K80.8 Other cholelithiasis
0.823 0.177 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.818 0.182 0.000
S70-S79 Injuries to the hip and thigh
0.818 0.182 0.000
J02 Acute pharyngitis
0.816 0.184 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.815 0.185 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.813 0.187 0.000
H43-H45 Disorders of vitreous body and globe
0.812 0.188 0.000
M19 Other arthrosis
0.810 0.190 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.808 0.192 0.000
Q60-Q64 Congenital malformations of the urinary system
0.801 0.199 0.000
M25.9 Joint disorder, unspecified
0.798 0.202 0.000
M11 Other crystal arthropathies
0.798 0.202 0.000
M31 Other necrotising vasculopathies
0.794 0.206 0.000
M22 Disorders of patella
0.792 0.208 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.790 0.210 0.000
S90 Superficial injury of ankle and foot
0.789 0.211 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.788 0.212 0.000
K02 Dental caries
0.788 0.212 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.788 0.212 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.788 0.212 0.000
K80.4 Calculus of bile duct with cholecystitis
0.786 0.213 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.785 0.215 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.784 0.216 0.000
E89.0 Postprocedural hypothyroidism
0.783 0.217 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.782 0.218 0.000
S92 Fracture of foot, except ankle
0.782 0.218 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.782 0.218 0.000
I60-I69 Cerebrovascular diseases
0.782 0.218 0.000
M32 Systemic lupus erythematosus
0.780 0.220 0.000
Chapter IX Diseases of the circulatory system
0.777 0.223 0.000
H31 Other disorders of choroid
0.773 0.227 0.000
K65-K67 Diseases of peritoneum
0.771 0.229 0.000
L20-L30 Dermatitis and eczema
0.769 0.231 0.000
M10.0 Idiopathic gout
0.769 0.231 0.000
H20 Iridocyclitis
0.768 0.232 0.000
L40.0 Psoriasis vulgaris
0.767 0.233 0.000
E29 Testicular dysfunction
0.766 0.234 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.765 0.235 0.000
M25.4 Effusion of joint
0.765 0.235 0.000
D68.2 Hereditary deficiency of other clotting factors
0.763 0.237 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.763 0.237 0.000
J02.9 Acute pharyngitis, unspecified
0.762 0.238 0.000
M34 Systemic sclerosis
0.761 0.239 0.000
D80-D89 Certain disorders involving the immune mechanism
0.761 0.239 0.000
K82.9 Disease of gallbladder, unspecified
0.758 0.242 0.000
M65 Synovitis and tenosynovitis
0.758 0.242 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.757 0.243 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.756 0.244 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.756 0.244 0.000
S00-S09 Injuries to the head
0.755 0.245 0.000
H35.2 Other proliferative retinopathy
0.755 0.245 0.000
M17.3 Other posttraumatic gonarthrosis
0.754 0.246 0.000
S10-S19 Injuries to the neck
0.753 0.247 0.000
H35.0 Background retinopathy and retinal vascular changes
0.753 0.247 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.752 0.248 0.000
M80.8 Other osteoporosis with pathological fracture
0.751 0.249 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.751 0.249 0.000
H33.3 Retinal breaks without detachment
0.749 0.251 0.000
E10.8 With unspecified complications
0.748 0.252 0.000
H53-H54 Visual disturbances and blindness
0.747 0.252 0.000
D68.5 Primary Thrombophilia
0.747 0.253 0.000
K02.9 Dental caries, unspecified
0.747 0.253 0.000
L43 Lichen planus
0.746 0.254 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.746 0.254 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.745 0.255 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.745 0.255 0.000
M13 Other arthritis
0.744 0.256 0.000
K11 Diseases of salivary glands
0.744 0.256 0.000
I60 Subarachnoid haemorrhage
0.744 0.256 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.743 0.257 0.000
M25.8 Other specified joint disorders
0.743 0.257 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.742 0.257 0.000
J60-J70 Lung diseases due to external agents
0.742 0.258 0.000
E27.9 Disorder of adrenal gland, unspecified
0.741 0.259 0.000
T00-T07 Injuries involving multiple body regions
0.739 0.261 0.000
E27.2 Addisonian crisis
0.737 0.263 0.000
S29 Other and unspecified injuries of thorax
0.734 0.265 0.000
M84 Disorders of continuity of bone
0.734 0.266 0.000
M25.76 Osteophyte (Lower leg)
0.733 0.267 0.000
J90-J94 Other diseases of pleura
0.733 0.267 0.000
M81 Osteoporosis without pathological fracture
0.733 0.267 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.732 0.268 0.000
K36 Other appendicitis
0.731 0.269 0.000
M60-M63 Disorders of muscles
0.730 0.269 0.000
D68.6 Other Thrombophilia
0.729 0.271 0.000
E20 Hypoparathyroidism
0.729 0.271 0.000
S91 Open wound of ankle and foot
0.729 0.271 0.000
M25.71 Osteophyte (Shoulder region)
0.728 0.272 0.000
T66-T78 Other and unspecified effects of external causes
0.728 0.272 0.000
M86-M90 Other osteopathies
0.727 0.273 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.727 0.273 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.725 0.275 0.000
E80.4 Gilbert's syndrome
0.725 0.275 0.000
H33.0 Retinal detachment with retinal break
0.724 0.276 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.723 0.277 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.723 0.277 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.722 0.277 0.000
E10.1 With ketoacidosis
0.722 0.278 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E05.8 Other thyrotoxicosis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
M15 Polyarthrosis
0.716 0.283 0.000
M07.3 Other psoriatic arthropathies
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.716 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.716 0.284 0.000
Q80-Q89 Other congenital malformations
0.715 0.285 0.000
K90.8 Other intestinal malabsorption
0.715 0.285 0.000
K90.3 Pancreatic steatorrhoea
0.715 0.285 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.715 0.285 0.000
K90.1 Tropical sprue
0.715 0.285 0.000
E03 Other hypothyroidism
0.714 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.714 0.286 0.000
J43.9 Emphysema, unspecified
0.714 0.286 0.000
S21 Open wound of thorax
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.286 0.000
H43 Disorders of vitreous body
0.713 0.287 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.713 0.287 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
M12 Other specific arthropathies
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
E23.6 Other disorders of pituitary gland
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
Chapter V Mental and behavioural disorders
0.709 0.291 0.000
S70 Superficial injury of hip and thigh
0.709 0.291 0.000
E28 Ovarian dysfunction
0.708 0.292 0.000
M17.5 Other secondary gonarthrosis
0.708 0.292 0.000
S99 Other and unspecified injuries of ankle and foot
0.708 0.292 0.000
E04 Other non-toxic goitre
0.707 0.292 0.000
J45.8 Mixed asthma
0.707 0.293 0.000
J45.1 Nonallergic asthma
0.707 0.293 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.707 0.293 0.000
E07 Other disorders of thyroid
0.707 0.293 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.707 0.293 0.000
M06.0 Seronegative rheumatoid arthritis
0.706 0.294 0.000
K82.1 Hydrops of gallbladder
0.705 0.295 0.000
T90 Sequelae of injuries of head
0.705 0.295 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.704 0.296 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.704 0.296 0.000
J06.9 Acute upper respiratory infection, unspecified
0.703 0.297 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.703 0.297 0.000
T92 Sequelae of injuries of upper limb
0.703 0.297 0.000
M25.74 Osteophyte (Hand)
0.702 0.298 0.000
K80.3 Calculus of bile duct with cholangitis
0.702 0.298 0.000
M19.0 Primary arthrosis of other joints
0.702 0.298 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.702 0.298 0.000
D68.9 Coagulation defect, unspecified
0.701 0.299 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.701 0.299 0.000
E32 Diseases of thymus
0.701 0.299 0.000
E31 Polyglandular dysfunction
0.701 0.299 0.000
E30 Disorders of puberty, not elsewhere classified
0.701 0.299 0.000
E26 Hyperaldosteronism
0.701 0.299 0.000
E25 Adrenogenital disorders
0.701 0.299 0.000
E23.2 Diabetes insipidus
0.701 0.299 0.000
M25.0 Haemarthrosis
0.699 0.300 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.699 0.301 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.699 0.301 0.000
H30 Chorioretinal inflammation
0.699 0.301 0.000
L40.5 Arthropathic psoriasis
0.699 0.301 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.697 0.303 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.697 0.303 0.000
T33-T35 Frostbite
0.697 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.697 0.303 0.000
J92 Pleural plaque
0.696 0.304 0.000
M06.8 Other specified rheumatoid arthritis
0.695 0.305 0.000
M06.4 Inflammatory polyarthropathy
0.695 0.305 0.000
M06.3 Rheumatoid nodule
0.695 0.305 0.000
M06.2 Rheumatoid bursitis
0.695 0.305 0.000
M06.1 Adult-onset Still's disease
0.695 0.305 0.000
E34 Other endocrine disorders
0.695 0.305 0.000
E12 Malnutrition-related diabetes mellitus
0.695 0.305 0.000
M35.1 Other overlap syndromes
0.695 0.305 0.000
D68.0 Von Willebrand's disease
0.694 0.306 0.000
D61 Other aplastic anaemias
0.693 0.307 0.000
E23.7 Disorder of pituitary gland, unspecified
0.693 0.307 0.000
H35.5 Hereditary retinal dystrophy
0.691 0.308 0.000
H35.1 Retinopathy of prematurity
0.691 0.308 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.308 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.691 0.309 0.000
H35.3 Degeneration of macula and posterior pole
0.690 0.310 0.000
J01 Acute sinusitis
0.689 0.310 0.000
M25.3 Other instability of joint
0.689 0.311 0.000
M25.2 Flail joint
0.689 0.311 0.000
M25.1 Fistula of joint
0.689 0.311 0.000
J98 Other respiratory disorders
0.688 0.312 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.686 0.314 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.686 0.314 0.000
E10.7 With multiple complications
0.685 0.314 0.000
E10.6 With other specified complications
0.685 0.314 0.000
E10.0 With coma
0.685 0.314 0.000
M83 Adult osteomalacia
0.685 0.315 0.000
M25.72 Osteophyte (Upper arm)
0.685 0.315 0.000
M35.3 Polymyalgia rheumatica
0.685 0.315 0.000
E13 Other specified diabetes mellitus
0.684 0.316 0.000
M25.78 Osteophyte (Other)
0.683 0.317 0.000
E14 Unspecified diabetes mellitus
0.683 0.317 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.683 0.317 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.682 0.318 0.000
E06 Thyroiditis
0.681 0.319 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.681 0.319 0.000
H35.6 Retinal haemorrhage
0.680 0.320 0.000
M21 Other acquired deformities of limbs
0.680 0.320 0.000
I62 Other nontraumatic intracranial haemorrhage
0.680 0.320 0.000
K12 Stomatitis and related lesions
0.680 0.320 0.000
H36 Retinal disorders in diseases classified elsewhere
0.678 0.321 0.000
E88 Other metabolic disorders
0.678 0.322 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.677 0.322 0.000
M82 Osteoporosis in diseases classified elsewhere
0.677 0.323 0.000
Chapter XX External causes of morbidity and mortality
0.676 0.324 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.676 0.324 0.000
D67 Hereditary factor IX deficiency
0.676 0.324 0.000
D66 Hereditary factor VIII deficiency
0.676 0.324 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.676 0.324 0.000
E24 Cushing's syndrome
0.675 0.325 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.675 0.325 0.000
K09 Cysts of oral region, not elsewhere classified
0.674 0.326 0.000
M24.0 Loose body in joint
0.674 0.326 0.000
S98 Traumatic amputation of ankle and foot
0.673 0.327 0.000
S97 Crushing injury of ankle and foot
0.673 0.327 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.673 0.327 0.000
S95 Injury of blood vessels at ankle and foot level
0.673 0.327 0.000
S94 Injury of nerves at ankle and foot level
0.673 0.327 0.000
M91-M94 Chondropathies
0.672 0.328 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
M85 Other disorders of bone density and structure
0.670 0.330 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.669 0.331 0.000
K65 Peritonitis
0.668 0.332 0.000
D62 Acute posthaemorrhagic anaemia
0.668 0.332 0.000
E89.3 Postprocedural hypopituitarism
0.667 0.333 0.000
E27.8 Other specified disorders of adrenal gland
0.666 0.333 0.000
E27.5 Adrenomedullary hyperfunction
0.666 0.333 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.666 0.333 0.000
E27.0 Other adrenocortical overactivity
0.666 0.333 0.000
M24.2 Disorder of ligament
0.664 0.336 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.664 0.336 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.664 0.336 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.664 0.336 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.664 0.336 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.664 0.336 0.000
D68.4 Acquired coagulation factor deficiency
0.663 0.337 0.000
D68.1 Hereditary factor XI deficiency
0.663 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.663 0.337 0.000
L10-L14 Bullous disorders
0.663 0.337 0.000
I67 Other cerebrovascular diseases
0.662 0.338 0.000
E10.2 With renal complications
0.661 0.339 0.000
S92.3 Fracture of metatarsal bone
0.661 0.339 0.000
Chapter XXII Codes for special purposes
0.661 0.339 0.000
M24.1 Other articular cartilage disorders
0.660 0.340 0.000
Q63 Other congenital malformations of kidney
0.659 0.341 0.000
M25.79 Osteophyte (Site unspecified)
0.659 0.341 0.000
M25.73 Osteophyte (Forearm)
0.659 0.341 0.000
M25.70 Osteophyte (Multiple sites)
0.659 0.341 0.000
S92.4 Fracture of great toe
0.659 0.341 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.658 0.341 0.000
D69 Purpura and other haemorrhagic conditions
0.658 0.342 0.000
M22.8 Other disorders of patella
0.658 0.342 0.000
J03 Acute tonsillitis
0.657 0.342 0.000
M11.2 Other chondrocalcinosis
0.657 0.343 0.000
S27 Injury of other and unspecified intrathoracic organs
0.657 0.343 0.000
E10.5 With peripheral circulatory complications
0.657 0.343 0.000
L08 Other local infections of skin and subcutaneous tissue
0.657 0.343 0.000
M05 Seropositive rheumatoid arthritis
0.657 0.343 0.000
H20.9 Iridocyclitis, unspecified
0.657 0.343 0.000
K85 Acute pancreatitis
0.656 0.344 0.000
Q00-Q07 Congenital malformations of the nervous system
0.656 0.344 0.000
E73 Lactose intolerance
0.656 0.344 0.000
H33.1 Retinoschisis and retinal cysts
0.655 0.345 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.655 0.345 0.000
T91 Sequelae of injuries of neck and trunk
0.655 0.345 0.000
S93.1 Dislocation of toe(s)
0.654 0.346 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.654 0.346 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.654 0.346 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.654 0.346 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.654 0.346 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.654 0.346 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.654 0.346 0.000
Q50-Q56 Congenital malformations of genital organs
0.654 0.346 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.652 0.348 0.000
M35.8 Other specified systemic involvement of connective tissue
0.652 0.348 0.000
M35.7 Hypermobility syndrome
0.652 0.348 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.652 0.348 0.000
M35.5 Multifocal fibrosclerosis
0.652 0.348 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.652 0.348 0.000
M35.2 Behcet's disease
0.652 0.348 0.000
E40-E46 Malnutrition
0.651 0.349 0.000
H20.1 Chronic iridocyclitis
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.649 0.350 0.000
L44 Other papulosquamous disorders
0.648 0.352 0.000
L41 Parapsoriasis
0.648 0.352 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.648 0.352 0.000
L42 Pityriasis rosea
0.648 0.352 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.648 0.352 0.000
L05 Pilonidal cyst
0.647 0.353 0.000
K07 Dentofacial anomalies [including malocclusion]
0.646 0.354 0.000
E10.4 With neurological complications
0.644 0.356 0.000
S90.3 Contusion of other and unspecified parts of foot
0.642 0.357 0.000
K00 Disorders of tooth development and eruption
0.642 0.358 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.640 0.360 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.640 0.360 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.640 0.360 0.000
J92.0 Pleural plaque with presence of asbestos
0.640 0.360 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.639 0.361 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.639 0.361 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.638 0.362 0.000
S29.9 Unspecified injury of thorax
0.637 0.363 0.000
S20 Superficial injury of thorax
0.637 0.363 0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.636 0.364 0.000
K02.1 Caries of dentin
0.636 0.364 0.000
M40-M43 Deforming dorsopathies
0.635 0.364 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.635 0.365 0.000
K38 Other diseases of appendix
0.634 0.365 0.000
L43.9 Lichen planus, unspecified
0.634 0.366 0.000
S71 Open wound of hip and thigh
0.633 0.367 0.000
K82.4 Cholesterolosis of gallbladder
0.633 0.367 0.000
K82.2 Perforation of gallbladder
0.633 0.367 0.000
S43.1 Dislocation of acromioclavicular joint
0.632 0.368 0.000
E21.0 Primary hyperparathyroidism
0.632 0.368 0.000
E16 Other disorders of pancreatic internal secretion
0.631 0.368 0.000
L40.8 Other psoriasis
0.630 0.370 0.000
L40.4 Guttate psoriasis
0.630 0.370 0.000
L40.3 Pustulosis palmaris et plantaris
0.630 0.370 0.000
L40.2 Acrodermatitis continua
0.630 0.370 0.000
L40.1 Generalised pustular psoriasis
0.630 0.370 0.000
T79-T79 Certain early complications of trauma
0.630 0.370 0.000
M24.5 Contracture of joint
0.630 0.370 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.629 0.370 0.000
E85 Amyloidosis
0.628 0.372 0.000
E84 Cystic fibrosis
0.628 0.372 0.000
E79 Disorders of purine and pyrimidine metabolism
0.628 0.372 0.000
E77 Disorders of glycoprotein metabolism
0.628 0.372 0.000
E76 Disorders of glycosaminoglycan metabolism
0.628 0.372 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.628 0.372 0.000
E72 Other disorders of amino-acid metabolism
0.628 0.372 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.628 0.372 0.000
E70 Disorders of aromatic amino-acid metabolism
0.628 0.372 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.628 0.372 0.000
M19.1 Posttraumatic arthrosis of other joints
0.628 0.372 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.628 0.372 0.000
H31.0 Chorioretinal scars
0.628 0.372 0.000
M31.3 Wegener's granulomatosis
0.628 0.372 0.000
S93.0 Dislocation of ankle joint
0.628 0.372 0.000
S80-S89 Injuries to the knee and lower leg
0.628 0.372 0.000
S00 Superficial injury of head
0.626 0.374 0.000
I71 Aortic aneurysm and dissection
0.626 0.374 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.625 0.375 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.624 0.376 0.000
S26 Injury of heart
0.624 0.376 0.000
S25 Injury of blood vessels of thorax
0.624 0.376 0.000
S24 Injury of nerves and spinal cord at thorax level
0.624 0.376 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.624 0.376 0.000
K11.9 Disease of salivary gland, unspecified
0.623 0.377 0.000
H50 Other strabismus
0.623 0.377 0.000
M24.9 Joint derangement, unspecified
0.621 0.379 0.000
M24.7 Protrusio acetabuli
0.621 0.379 0.000
M24.6 Ankylosis of joint
0.621 0.379 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.621 0.379 0.000
T90.4 Sequelae of injury of eye and orbit
0.621 0.379 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.621 0.379 0.000
D64 Other anaemias
0.620 0.380 0.000
J96 Respiratory failure, not elsewhere classified
0.619 0.381 0.000
J45.0 Predominantly allergic asthma
0.618 0.381 0.000
M67 Other disorders of synovium and tendon
0.618 0.382 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.618 0.382 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.617 0.383 0.000
H10-H13 Disorders of conjunctiva
0.617 0.383 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.616 0.384 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.616 0.384 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.616 0.384 0.000
T95 Sequelae of burns, corrosions and frostbite
0.615 0.385 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.615 0.385 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.615 0.385 0.000
E04.9 Non-toxic goitre, unspecified
0.615 0.385 0.000
M66 Spontaneous rupture of synovium and tendon
0.615 0.385 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.615 0.385 0.000
M22.2 Patellofemoral disorders
0.615 0.385 0.000
L28 Lichen simplex chronicus and prurigo
0.615 0.385 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.614 0.385 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.614 0.386 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.614 0.386 0.000
E23.1 Drug-induced hypopituitarism
0.614 0.386 0.000
E29.1 Testicular hypofunction
0.614 0.386 0.000
M10.4 Other secondary gout
0.613 0.387 0.000
M10.3 Gout due to impairment of renal function
0.613 0.387 0.000
M10.2 Drug-induced gout
0.613 0.387 0.000
M10.1 Lead-induced gout
0.613 0.387 0.000
H33.5 Other retinal detachments
0.613 0.387 0.000
H33.4 Traction detachment of retina
0.612 0.388 0.000
M65.8 Other synovitis and tenosynovitis
0.612 0.388 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.611 0.389 0.000
S70.1 Contusion of thigh
0.610 0.390 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.609 0.391 0.000
K11.5 Sialolithiasis
0.609 0.391 0.000
S90.8 Other superficial injuries of ankle and foot
0.609 0.391 0.000
M89 Other disorders of bone
0.608 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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