TreeWAS – Variant ID: rs77396437

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10-E14 Diabetes mellitus	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001
Chapter II Neoplasms	0.995	0.005
C64-C68 Malignant neoplasms of urinary tract	0.994	0.006
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.994	0.006
Chapter XXI Factors influencing health status and contact with health services	0.992	0.008
O34 Maternal care for known or suspected abnormality of pelvic organs	0.990	0.010
C67 Malignant neoplasm of bladder	0.989	0.011
O34.2 Maternal care due to uterine scar from previous surgery	0.986	0.014
E11.3 With ophthalmic complications	0.985	0.015
C15-C26 Malignant neoplasms of digestive organs	0.981	0.019
Z46.6 Fitting and adjustment of urinary device	0.981	0.019
Z46 Fitting and adjustment of other devices	0.978	0.022
Z40-Z54 Persons encountering health services for specific procedures and health care	0.972	0.028
C18 Malignant neoplasm of colon	0.969	0.031
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.966	0.034
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.966	0.034
E11.4 With neurological complications	0.963	0.037
C67.9 Bladder, unspecified	0.962	0.038
E10.3 With ophthalmic complications	0.954	0.046
Z60 Problems related to social environment	0.949	0.051
C18.0 Caecum	0.946	0.054
Chapter VII Diseases of the eye and adnexa	0.942	0.058
E20-E35 Disorders of other endocrine glands	0.941	0.059
H30-H36 Disorders of choroid and retina	0.938	0.062
Z60.2 Living alone	0.936	0.064
E11.2 With renal complications	0.931	0.069
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.930	0.070
C64 Malignant neoplasm of kidney, except renal pelvis	0.930	0.070
H36 Retinal disorders in diseases classified elsewhere	0.924	0.076
O20-O29 Other maternal disorders predominantly related to pregnancy	0.923	0.077
S50-S59 Injuries to the elbow and forearm	0.922	0.078
E10.9 Without complications	0.919	0.081
C67.6 Ureteric orifice	0.918	0.082
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.916	0.084
E10.1 With ketoacidosis	0.915	0.085
H36.0 Diabetic retinopathy	0.915	0.085
E10.4 With neurological complications	0.910	0.090
H35 Other retinal disorders	0.905	0.095
H53-H54 Visual disturbances and blindness	0.899	0.101
C18.7 Sigmoid colon	0.892	0.108
O85-O92 Complications predominantly related to the puerperium	0.888	0.112
E27 Other disorders of adrenal gland	0.888	0.112
S40-S49 Injuries to the shoulder and upper arm	0.886	0.114
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.877	0.123
H35.8 Other specified retinal disorders	0.876	0.124
O26 Maternal care for other conditions predominantly related to pregnancy	0.876	0.124
H54 Blindness and low vision	0.870	0.130
C18.9 Colon, unspecified	0.859	0.141
E16 Other disorders of pancreatic internal secretion	0.855	0.145
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.853	0.147
E10.2 With renal complications	0.853	0.147
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.852	0.148
O35 Maternal care for known or suspected foetal abnormality and damage	0.850	0.150
O44 Placenta praevia	0.845	0.155
O26.9 Pregnancy-related condition, unspecified	0.841	0.159
E10.0 With coma	0.840	0.160
S20-S29 Injuries to the thorax	0.838	0.162
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.829	0.171
C67.5 Bladder neck	0.829	0.171
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.829	0.171
E10.6 With other specified complications	0.826	0.174
O42 Premature rupture of membranes	0.826	0.174
E14 Unspecified diabetes mellitus	0.825	0.175
S52 Fracture of forearm	0.824	0.176
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.824	0.176
H54.0 Blindness, both eyes	0.821	0.179
E11.6 With other specified complications	0.821	0.179
Z41 Procedures for purposes other than remedying health state	0.819	0.181
Z46.8 Fitting and adjustment of other specified devices	0.814	0.186
E16.2 Hypoglycaemia, unspecified	0.812	0.188
C65 Malignant neoplasm of renal pelvis	0.810	0.190
C16 Malignant neoplasm of stomach	0.807	0.193
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.803	0.197
Z52 Donors of organs and tissues	0.803	0.197
H35.2 Other proliferative retinopathy	0.799	0.201
O30 Multiple gestation	0.798	0.202
E65-E68 Obesity and other hyperalimentation	0.796	0.204
C15 Malignant neoplasm of oesophagus	0.796	0.204
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.795	0.205
E10.5 With peripheral circulatory complications	0.792	0.208
S42 Fracture of shoulder and upper arm	0.792	0.208
E11.8 With unspecified complications	0.789	0.210
H35.9 Retinal disorder, unspecified	0.787	0.213
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.782	0.218
S56 Injury of muscle and tendon at forearm level	0.782	0.218
S60-S69 Injuries to the wrist and hand	0.782	0.218
C91 Lymphoid leukaemia	0.781	0.219
C19 Malignant neoplasm of rectosigmoid junction	0.781	0.219
E40-E46 Malnutrition	0.781	0.219
O47 False labour	0.780	0.220
O60-O75 Complications of labour and delivery	0.780	0.220
C20 Malignant neoplasm of rectum	0.778	0.222
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.775	0.225
Z46.3 Fitting and adjustment of dental prosthetic device	0.774	0.225
S20 Superficial injury of thorax	0.772	0.228
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.767	0.233
S90-S99 Injuries to the ankle and foot	0.762	0.238
E29 Testicular dysfunction	0.762	0.238
E27.4 Other and unspecified adrenocortical insufficiency	0.762	0.238
Z36 Antenatal screening	0.761	0.239
E13 Other specified diabetes mellitus	0.761	0.239
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.760	0.240
O34.7 Maternal care for abnormality of vulva and perineum	0.755	0.245
C88 Malignant immunoproliferative diseases	0.750	0.250
S70-S79 Injuries to the hip and thigh	0.750	0.250
S50 Superficial injury of forearm	0.749	0.250
S42.0 Fracture of clavicle	0.749	0.251
O44.1 Placenta praevia with haemorrhage	0.745	0.254
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.745	0.255
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.745	0.255
O34.4 Maternal care for other abnormalities of cervix	0.743	0.257
S52.5 Fracture of lower end of radius	0.743	0.257
D00-D09 In situ neoplasms	0.743	0.257
Z56 Problems related to employment and unemployment	0.741	0.259
Z44 Fitting and adjustment of external prosthetic device	0.741	0.259
S49 Other and unspecified injuries of shoulder and upper arm	0.741	0.259
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.739	0.261
T87 Complications peculiar to reattachment and amputation	0.739	0.261
C92 Myeloid leukaemia	0.738	0.262
H46-H48 Disorders of optic nerve and visual pathways	0.737	0.263
C18.6 Descending colon	0.737	0.263
Chapter I Certain infectious and parasitic diseases	0.736	0.264
C67.0 Trigone of bladder	0.733	0.267
S40 Superficial injury of shoulder and upper arm	0.731	0.269
Z57 Occupational exposure to risk-factors	0.731	0.269
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.731	0.269
Z36.9 Antenatal screening, unspecified	0.730	0.270
C67.2 Lateral wall of bladder	0.730	0.270
C26 Malignant neoplasm of other and ill-defined digestive organs	0.729	0.271
O47.1 False labour at or after 37 completed weeks of gestation	0.725	0.275
O32 Maternal care for known or suspected malpresentation of foetus	0.724	0.275
O80-O84 Delivery	0.724	0.276
Chapter IX Diseases of the circulatory system	0.722	0.278
O72 Postpartum haemorrhage	0.722	0.278
Z70-Z76 Persons encountering health services in other circumstances	0.722	0.278
S80-S89 Injuries to the knee and lower leg	0.721	0.279
T20-T25 Burns and corrosions of external body surface, specified by site	0.719	0.281
O23 Infections of genito-urinary tract in pregnancy	0.719	0.281
S42.00 Fracture of clavicle (closed)	0.718	0.282
E11.0 With coma	0.718	0.282
O22 Venous complications in pregnancy	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E11.7 With multiple complications	0.716	0.284
E27.8 Other specified disorders of adrenal gland	0.716	0.284
S20.2 Contusion of thorax	0.716	0.284
O85 Puerperal sepsis	0.715	0.285
O90 Complications of the puerperium, not elsewhere classified	0.714	0.286
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
C68 Malignant neoplasm of other and unspecified urinary organs	0.713	0.287
O45 Premature separation of placenta [abruptio placentae]	0.712	0.288
O33 Maternal care for known or suspected disproportion	0.712	0.288
O31 Complications specific to multiple gestation	0.712	0.288
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.712	0.288
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.712	0.288
E27.1 Primary adrenocortical insufficiency	0.711	0.289
C97 Malignant neoplasms of independent (primary) multiple sites	0.710	0.289
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.709	0.290
O34.8 Maternal care for other abnormalities of pelvic organs	0.709	0.290
O34.6 Maternal care for abnormality of vagina	0.709	0.290
O34.5 Maternal care for other abnormalities of gravid uterus	0.709	0.290
O34.3 Maternal care for cervical incompetence	0.709	0.290
O34.1 Maternal care for tumour of corpus uteri	0.709	0.290
O34.0 Maternal care for congenital malformation of uterus	0.709	0.290
C67.8 Overlapping lesion of bladder	0.709	0.291
C67.7 Urachus	0.709	0.291
Z46.7 Fitting and adjustment of orthopaedic device	0.709	0.291
T00-T07 Injuries involving multiple body regions	0.709	0.291
E14.3 With ophthalmic complications	0.708	0.292
Z54 Convalescence	0.706	0.294
T82.3 Mechanical complication of other vascular grafts	0.704	0.296
C16.0 Cardia	0.704	0.296
C23 Malignant neoplasm of gallbladder	0.704	0.296
C15.4 Middle third of oesophagus	0.703	0.297
O16 Unspecified maternal hypertension	0.702	0.298
C67.1 Dome of bladder	0.702	0.298
S52.6 Fracture of lower end of both ulna and radius	0.702	0.298
C66 Malignant neoplasm of ureter	0.701	0.299
Q38-Q45 Other congenital malformations of the digestive system	0.701	0.299
Z46.9 Fitting and adjustment of other unspecified device	0.701	0.299
Z46.4 Fitting and adjustment of orthodontic device	0.701	0.299
Z46.1 Fitting and adjustment of hearing aid	0.701	0.299
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.701	0.299
H54.9 Unspecified visual impairment (binocular)	0.700	0.300
C67.4 Posterior wall of bladder	0.699	0.300
E34 Other endocrine disorders	0.699	0.301
E27.9 Disorder of adrenal gland, unspecified	0.698	0.302
C18.1 Appendix	0.697	0.303
Z40 Prophylactic surgery	0.696	0.303
E20 Hypoparathyroidism	0.696	0.304
S10-S19 Injuries to the neck	0.695	0.304
C18.8 Overlapping lesion of colon	0.695	0.305
E11.5 With peripheral circulatory complications	0.695	0.305
H43-H45 Disorders of vitreous body and globe	0.694	0.306
T33-T35 Frostbite	0.693	0.307
T26-T28 Burns and corrosions confined to eye and internal organs	0.693	0.307
Z65 Problems related to other psychosocial circumstances	0.693	0.307
Z64 Problems related to certain psychosocial circumstances	0.693	0.307
Z62 Other problems related to upbringing	0.693	0.307
Z61 Problems related to negative life events in childhood	0.693	0.307
Z59 Problems related to housing and economic circumstances	0.693	0.307
Z58 Problems related to physical environment	0.693	0.307
Z55 Problems related to education and literacy	0.693	0.307
Z33 Pregnant state, incidental	0.690	0.310
Z00-Z13 Persons encountering health services for examination and investigation	0.690	0.310
T15-T19 Effects of foreign body entering through natural orifice	0.689	0.311
H54.4 Blindness, one eye	0.688	0.312
O87 Venous complications in the puerperium	0.688	0.312
O63 Long labour	0.687	0.313
S52.50 Fracture of lower end of radius (closed)	0.685	0.315
C21 Malignant neoplasm of anus and anal canal	0.685	0.315
C17 Malignant neoplasm of small intestine	0.684	0.315
S51 Open wound of forearm	0.685	0.315
Z41.8 Other procedures for purposes other than remedying health state	0.682	0.318
C85.1 B-cell lymphoma, unspecified	0.682	0.318
C67.3 Anterior wall of bladder	0.682	0.318
I20-I25 Ischaemic heart diseases	0.681	0.319
E27.2 Addisonian crisis	0.681	0.319
C84 Peripheral and cutaneous T-cell lymphomas	0.680	0.319
S64 Injury of nerves at wrist and hand level	0.681	0.319
O40 Polyhydramnios	0.680	0.320
O42.9 Premature rupture of membranes, unspecified	0.680	0.320
Z60.9 Problem related to social environment, unspecified	0.680	0.320
Z60.8 Other problems related to social environment	0.680	0.320
Z60.5 Target of perceived adverse discrimination and persecution	0.680	0.320
Z60.4 Social exclusion and rejection	0.680	0.320
Z60.3 Acculturation difficulty	0.680	0.320
Z60.1 Atypical parenting situation	0.680	0.320
Z60.0 Problems of adjustment to life-cycle transitions	0.680	0.320
O41 Other disorders of amniotic fluid and membranes	0.680	0.320
T80 Complications following infusion, transfusion and therapeutic injection	0.680	0.320
O86 Other puerperal infections	0.679	0.321
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.677	0.323
E22 Hyperfunction of pituitary gland	0.677	0.323
C18.2 Ascending colon	0.676	0.323
O75 Other complications of labour and delivery, not elsewhere classified	0.677	0.323
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.676	0.324
H35.7 Separation of retinal layers	0.676	0.324
H31 Other disorders of choroid	0.675	0.325
E35 Disorders of endocrine glands in diseases classified elsewhere	0.675	0.325
E32 Diseases of thymus	0.675	0.325
E31 Polyglandular dysfunction	0.675	0.325
E30 Disorders of puberty, not elsewhere classified	0.675	0.325
E26 Hyperaldosteronism	0.675	0.325
E25 Adrenogenital disorders	0.675	0.325
H32 Chorioretinal disorders in diseases classified elsewhere	0.672	0.327
H30 Chorioretinal inflammation	0.672	0.327
T88 Other complications of surgical and medical care, not elsewhere classified	0.670	0.330
O94-O99 Other obstetric conditions, not elsewhere classified	0.669	0.331
Q50-Q56 Congenital malformations of genital organs	0.669	0.331
Z48 Other surgical follow-up care	0.669	0.331
T82.4 Mechanical complication of vascular dialysis catheter	0.669	0.331
H54.7 Unspecified visual loss	0.668	0.332
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.667	0.333
C95 Leukaemia of unspecified cell type	0.667	0.333
C94 Other leukaemias of specified cell type	0.667	0.333
C93 Monocytic leukaemia	0.667	0.333
C86 Other specified types of T/NK-cell lymphoma	0.667	0.333
O24 Diabetes mellitus in pregnancy	0.667	0.333
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.667	0.333
E66 Obesity	0.667	0.333
C73 Malignant neoplasm of thyroid gland	0.665	0.335
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.664	0.336
E11.1 With ketoacidosis	0.664	0.336
H36.8 Other retinal disorders in diseases classified elsewhere	0.663	0.337
O29 Complications of anaesthesia during pregnancy	0.661	0.338
O28 Abnormal findings on antenatal screening of mother	0.661	0.338
O25 Malnutrition in pregnancy	0.661	0.338
S59 Other and unspecified injuries of forearm	0.661	0.339
S58 Traumatic amputation of forearm	0.661	0.339
S57 Crushing injury of forearm	0.661	0.339
S55 Injury of blood vessels at forearm level	0.661	0.339
S54 Injury of nerves at forearm level	0.661	0.339
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.661	0.339
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.660	0.339
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.659	0.341
O30.0 Twin pregnancy	0.658	0.341
D05 Carcinoma in situ of breast	0.659	0.341
E15 Nondiabetic hypoglycaemic coma	0.656	0.343
O72.1 Other immediate postpartum haemorrhage	0.656	0.344
Z43 Attention to artificial openings	0.656	0.344
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.653	0.346
Z52.4 Kidney donor	0.653	0.347
T79-T79 Certain early complications of trauma	0.651	0.349
S81 Open wound of lower leg	0.651	0.349
H35.5 Hereditary retinal dystrophy	0.649	0.351
H35.1 Retinopathy of prematurity	0.649	0.351
C81 Hodgkin's disease	0.648	0.351
O21 Excessive vomiting in pregnancy	0.648	0.352
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.647	0.353
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.646	0.353
C18.4 Transverse colon	0.645	0.355
Z49 Care involving dialysis	0.645	0.355
Chapter XX External causes of morbidity and mortality	0.644	0.356
Z45 Adjustment and management of implanted device	0.643	0.357
S50.0 Contusion of elbow	0.642	0.358
S20.3 Other superficial injuries of front wall of thorax	0.642	0.358
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.640	0.360
H55-H59 Other disorders of eye and adnexa	0.638	0.362
O71 Other obstetric trauma	0.637	0.363
O92 Other disorders of breast and lactation associated with childbirth	0.637	0.363
O91 Infections of breast associated with childbirth	0.637	0.363
O89 Complications of anaesthesia during the puerperium	0.637	0.363
O88 Obstetric embolism	0.637	0.363
E27.5 Adrenomedullary hyperfunction	0.637	0.363
E27.3 Drug-induced adrenocortical insufficiency	0.637	0.363
E27.0 Other adrenocortical overactivity	0.637	0.363
E24 Cushing's syndrome	0.636	0.363
S48 Traumatic amputation of shoulder and upper arm	0.635	0.365
S45 Injury of blood vessels at shoulder and upper arm level	0.635	0.365
S44 Injury of nerves at shoulder and upper arm level	0.635	0.365
S47 Crushing injury of shoulder and upper arm	0.635	0.365
E29.1 Testicular hypofunction	0.634	0.366
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.633	0.367
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.633	0.367
O26.8 Other specified pregnancy-related conditions	0.632	0.368
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.632	0.368
Z47 Other orthopaedic follow-up care	0.631	0.369
C91.0 Acute lymphoblastic leukaemia	0.631	0.369
T82.0 Mechanical complication of heart valve prosthesis	0.629	0.370
H53 Visual disturbances	0.629	0.371
T85 Complications of other internal prosthetic devices, implants and grafts	0.629	0.371
E21.3 Hyperparathyroidism, unspecified	0.629	0.371
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.629	0.371
S29 Other and unspecified injuries of thorax	0.629	0.371
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.628	0.372
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.628	0.372
O26.5 Maternal hypotension syndrome	0.628	0.372
O26.4 Herpes gestationis	0.628	0.372
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.628	0.372
O26.2 Pregnancy care of habitual aborter	0.628	0.372
O26.1 Low weight gain in pregnancy	0.628	0.372
O26.0 Excessive weight gain in pregnancy	0.628	0.372
E70-E90 Metabolic disorders	0.628	0.372
C16.3 Pyloric antrum	0.626	0.374
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.626	0.374
T87.6 Other and unspecified complications of amputation stump	0.625	0.375
S32 Fracture of lumbar spine and pelvis	0.624	0.376
H54.6 Unqualified visual loss, one eye	0.624	0.376
H54.5 Low vision, one eye	0.624	0.376
H54.3 Unqualified visual loss, both eyes	0.624	0.376
H54.2 Low vision, both eyes	0.624	0.376
H54.1 Blindness, one eye, low vision, other eye	0.624	0.376
E46 Unspecified protein-energy malnutrition	0.623	0.377
C91.1 Chronic lymphocytic leukaemia	0.623	0.377
I24 Other acute ischaemic heart diseases	0.623	0.377
E28 Ovarian dysfunction	0.621	0.379
C90 Multiple myeloma and malignant plasma cell neoplasms	0.621	0.379
C92.1 Chronic myeloid leukaemia	0.621	0.379
C88.0 Waldenstrom's macroglobulinaemia	0.620	0.380
Z52.0 Blood donor	0.619	0.380
T83.0 Mechanical complication of urinary (indwelling) catheter	0.619	0.381
Z57.5 Occupational exposure to toxic agents in other industries	0.619	0.381
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.618	0.382
S41 Open wound of shoulder and upper arm	0.618	0.382
Z36.0 Antenatal screening for chromosomal anomalies	0.618	0.382
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.618	0.382
Z08 Follow-up examination after treatment for malignant neoplasm	0.618	0.382
S52.7 Multiple fractures of forearm	0.618	0.382
S69 Other and unspecified injuries of wrist and hand	0.616	0.384
E66.8 Other obesity	0.616	0.384
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.614	0.386
I05-I09 Chronic rheumatic heart diseases	0.614	0.386
S52.60 Fracture of lower end of both ulna and radius (closed)	0.614	0.386
E16.9 Disorder of pancreatic internal secretion, unspecified	0.613	0.387
E16.8 Other specified disorders of pancreatic internal secretion	0.613	0.387
E16.4 Abnormal secretion of gastrin	0.613	0.387
E16.3 Increased secretion of glucagon	0.613	0.387
E16.1 Other hypoglycaemia	0.613	0.387
E16.0 Drug-induced hypoglycaemia without coma	0.613	0.387
S65 Injury of blood vessels at wrist and hand level	0.613	0.387
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.613	0.387
O15 Eclampsia	0.611	0.388
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.611	0.388
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.611	0.389
S49.8 Other specified injuries of shoulder and upper arm	0.610	0.390
I20 Angina pectoris	0.610	0.390
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.610	0.390
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.610	0.390
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.610	0.390
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.610	0.390
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.610	0.390
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.610	0.390
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.610	0.390
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.610	0.390
S81.0 Open wound of knee	0.610	0.390
H34 Retinal vascular occlusions	0.609	0.390
Z40.8 Other prophylactic surgery	0.609	0.391
O43 Placental disorders	0.608	0.391
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.608	0.392
S50.1 Contusion of other and unspecified parts of forearm	0.608	0.392
S80 Superficial injury of lower leg	0.607	0.393
O46 Antepartum haemorrhage, not elsewhere classified	0.605	0.394
I70-I79 Diseases of arteries, arterioles and capillaries	0.604	0.396
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.604	0.396
O63.0 Prolonged first stage (of labour)	0.604	0.396
A50-A64 Infections with a predominantly sexual mode of transmission	0.603	0.397
S79 Other and unspecified injuries of hip and thigh	0.603	0.397
D05.9 Carcinoma in situ of breast, unspecified	0.602	0.398
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.602	0.398
S66 Injury of muscle and tendon at wrist and hand level	0.602	0.398
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.601	0.399
S26 Injury of heart	0.601	0.399
S25 Injury of blood vessels of thorax	0.601	0.399
S24 Injury of nerves and spinal cord at thorax level	0.601	0.399
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.601	0.399
S21 Open wound of thorax	0.601	0.399
B90-B94 Sequelae of infectious and parasitic diseases	0.600	0.400
A65-A69 Other spirochaetal diseases	0.600	0.400
Q43 Other congenital malformations of intestine	0.598	0.402
O32.1 Maternal care for breech presentation	0.597	0.403
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.593	0.407
C15.5 Lower third of oesophagus	0.593	0.407
Z71.8 Other specified counselling	0.593	0.407
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.593	0.407
O42.2 Premature rupture of membranes, labour delayed by therapy	0.592	0.408
E14.8 With unspecified complications	0.591	0.408
E14.7 With multiple complications	0.591	0.408
E14.6 With other specified complications	0.591	0.408
E14.5 With peripheral circulatory complications	0.591	0.408
E14.4 With neurological complications	0.591	0.408
E14.2 Withrenal complications	0.591	0.408
E14.1 With ketoacidosis	0.591	0.408
E14.0 With coma	0.591	0.408
O44.0 Placenta praevia specified as without haemorrhage	0.591	0.409
S52.9 Fracture of forearm, part unspecified	0.591	0.409
S52.4 Fracture of shafts of both ulna and radius	0.591	0.409
S52.3 Fracture of shaft of radius	0.591	0.409
S52.2 Fracture of shaft of ulna	0.591	0.409
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.591	0.409
Q35-Q37 Cleft lip and cleft palate	0.591	0.409
Q30-Q34 Congenital malformations of the respiratory system	0.591	0.409
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.591	0.409
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.591	0.409
Q00-Q07 Congenital malformations of the nervous system	0.591	0.409
E13.9 Without complications	0.590	0.410
I95-I99 Other and unspecified disorders of the circulatory system	0.590	0.410
O90.8 Other complications of the puerperium, not elsewhere classified	0.589	0.411
I22 Subsequent myocardial infarction	0.588	0.412
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.587	0.413
Z41.3 Ear piercing	0.587	0.413
Z41.2 Routine and ritual circumcision	0.587	0.413
Z41.0 Hair transplant	0.587	0.413
S52.1 Fracture of upper end of radius	0.587	0.413
T31 Burns classified according to extent of body surface involved	0.586	0.413
S64.4 Injury of digital nerve of other finger	0.586	0.414
S72 Fracture of femur	0.586	0.414
S92 Fracture of foot, except ankle	0.586	0.414
Q80-Q89 Other congenital malformations	0.583	0.416
S42.9 Fracture of shoulder girdle, part unspecified	0.583	0.417
E83 Disorders of mineral metabolism	0.583	0.417
O73 Retained placenta and membranes, without haemorrhage	0.583	0.417
S42.3 Fracture of shaft of humerus	0.582	0.418
Q54 Hypospadias	0.582	0.418
S91 Open wound of ankle and foot	0.581	0.419
I24.9 Acute ischaemic heart disease, unspecified	0.581	0.419
O82 Single delivery by Caesarean section	0.581	0.419
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.580	0.419
S42.2 Fracture of upper end of humerus	0.580	0.420
Z56.6 Other physical and mental strain related to work	0.580	0.420
H53.4 Visual field defects	0.579	0.421
H47 Other disorders of optic [2nd] nerve and visual pathways	0.579	0.421
Z63 Other problems related to primary support group, including family circumstances	0.578	0.421
C16.8 Overlapping lesion of stomach	0.578	0.421
C16.6 Greater curvature of stomach, unspecified	0.578	0.421
C16.5 Lesser curvature of stomach, unspecified	0.578	0.421
C16.4 Pylorus	0.578	0.421
C16.2 Body of stomach	0.578	0.421
C16.1 Fundus of stomach	0.578	0.421
O72.2 Delayed and secondary postpartum haemorrhage	0.577	0.423
C75 Malignant neoplasm of other endocrine glands and related structures	0.576	0.424
C74 Malignant neoplasm of adrenal gland	0.576	0.424
Z52.9 Donor of unspecified organ or tissue	0.576	0.424
Z52.8 Donor of other organs and tissues	0.576	0.424
Z52.7 Heart donor	0.576	0.424
Z52.6 Liver donor	0.576	0.424
Z52.5 Cornea donor	0.576	0.424
Z52.2 Bone donor	0.576	0.424
Z52.1 Skin donor	0.576	0.424
Z52.3 Bone marrow donor	0.575	0.424
Z44.3 Fitting and adjustment of external breast prosthesis	0.575	0.424
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.575	0.425
E14.9 Without complications	0.575	0.425
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.575	0.425
Z32 Pregnancy examination and test	0.574	0.425
S46 Injury of muscle and tendon at shoulder and upper arm level	0.574	0.426
H43 Disorders of vitreous body	0.574	0.426
B20-B24 Human immunodeficiency virus [HIV] disease	0.573	0.427
S49.9 Unspecified injury of shoulder and upper arm	0.573	0.427
Z36.2 Other antenatal screening based on amniocentesis	0.573	0.427
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.573	0.427
O30.9 Multiple gestation, unspecified	0.572	0.427
O30.8 Other multiple gestation	0.572	0.427

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations