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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77421486
log Bayes Factor = 2.96586
Chromosome 5   position 165,117,461  (GRCh37) Explore rs77421486 on Ensembl!
Variant rs77421486 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Z87 Personal history of other diseases and conditions
0.996 0.004 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.994 0.006 0.000
G40-G47 Episodic and paroxysmal disorders
0.993 0.007 0.000
Chapter XIV Diseases of the genitourinary system
0.989 0.011 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.979 0.021 0.000
Chapter XI Diseases of the digestive system
0.978 0.022 0.000
N30-N39 Other diseases of urinary system
0.975 0.025 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.966 0.034 0.000
Z87.1 Personal history of diseases of the digestive system
0.965 0.035 0.000
G40 Epilepsy
0.962 0.038 0.000
N30 Cystitis
0.960 0.040 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.950 0.050 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.945 0.055 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.941 0.059 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.937 0.063 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.936 0.064 0.000
Chapter I Certain infectious and parasitic diseases
0.933 0.067 0.000
Z90.1 Acquired absence of breast(s)
0.932 0.068 0.000
G47 Sleep disorders
0.931 0.069 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.927 0.073 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.921 0.079 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.912 0.088 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.907 0.093 0.000
G47.3 Sleep apnoea
0.900 0.100 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.898 0.102 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.895 0.105 0.000
N30.8 Other cystitis
0.895 0.105 0.000
K86 Other diseases of pancreas
0.891 0.109 0.000
K83 Other diseases of biliary tract
0.888 0.112 0.000
Z90.7 Acquired absence of genital organ(s)
0.885 0.115 0.000
N36 Other disorders of urethra
0.883 0.117 0.000
K82 Other diseases of gallbladder
0.882 0.117 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.877 0.123 0.000
K35-K38 Diseases of appendix
0.875 0.125 0.000
B95-B98 Bacterial, viral and other infectious agents
0.869 0.131 0.000
N83.2 Other and unspecified ovarian cysts
0.867 0.133 0.000
G81 Hemiplegia
0.865 0.135 0.000
Chapter XXII Codes for special purposes
0.864 0.136 0.000
Z90.5 Acquired absence of kidney
0.862 0.138 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.862 0.138 0.000
K50-K52 Noninfective enteritis and colitis
0.860 0.140 0.000
Z99.3 Dependence on wheelchair
0.859 0.141 0.000
G90-G99 Other disorders of the nervous system
0.857 0.143 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.855 0.145 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.847 0.153 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.847 0.153 0.000
Z88.6 Personal history of allergy to analgesic agent
0.842 0.158 0.000
N30.9 Cystitis, unspecified
0.837 0.163 0.000
Z90.8 Acquired absence of other organs
0.836 0.164 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.836 0.164 0.000
O60-O75 Complications of labour and delivery
0.832 0.168 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.828 0.172 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.827 0.173 0.000
N10-N16 Renal tubulo-interstitial diseases
0.824 0.176 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.823 0.177 0.000
Z99.8 Dependence on other enabling machines and devices
0.821 0.179 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.815 0.185 0.000
G81.9 Hemiplegia, unspecified
0.813 0.187 0.000
K70-K77 Diseases of liver
0.812 0.188 0.000
Z22 Carrier of infectious disease
0.809 0.191 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.808 0.192 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.801 0.199 0.000
Chapter VIII Diseases of the ear and mastoid process
0.801 0.199 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.799 0.201 0.000
K82.4 Cholesterolosis of gallbladder
0.797 0.203 0.000
N88 Other noninflammatory disorders of cervix uteri
0.797 0.203 0.000
G45.4 Transient global amnesia
0.795 0.205 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.791 0.209 0.000
N83.0 Follicular cyst of ovary
0.791 0.209 0.000
G40.9 Epilepsy, unspecified
0.782 0.218 0.000
N30.2 Other chronic cystitis
0.776 0.224 0.000
N36.8 Other specified disorders of urethra
0.776 0.224 0.000
N30.3 Trigonitis
0.772 0.228 0.000
Chapter V Mental and behavioural disorders
0.771 0.229 0.000
Z97 Presence of other devices
0.771 0.229 0.000
K35 Acute appendicitis
0.771 0.229 0.000
N95 Menopausal and other perimenopausal disorders
0.770 0.230 0.000
K51 Ulcerative colitis
0.768 0.232 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.767 0.232 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.767 0.233 0.000
K83.8 Other specified diseases of biliary tract
0.766 0.234 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.764 0.236 0.000
G30-G32 Other degenerative diseases of the nervous system
0.763 0.237 0.000
K90-K93 Other diseases of the digestive system
0.760 0.240 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.758 0.242 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.758 0.242 0.000
Z83 Family history of other specific disorders
0.749 0.251 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.749 0.251 0.000
N99-N99 Other disorders of the genitourinary system
0.748 0.252 0.000
G82 Paraplegia and tetraplegia
0.745 0.255 0.000
G93 Other disorders of brain
0.744 0.256 0.000
N30.1 Interstitial cystitis (chronic)
0.744 0.256 0.000
N32 Other disorders of bladder
0.743 0.257 0.000
K86.1 Other chronic pancreatitis
0.742 0.258 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.742 0.258 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.741 0.259 0.000
K83.0 Cholangitis
0.741 0.259 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.741 0.259 0.000
N93 Other abnormal uterine and vaginal bleeding
0.740 0.260 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.740 0.260 0.000
O47 False labour
0.739 0.261 0.000
Z29 Need for other prophylactic measures
0.739 0.261 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.736 0.264 0.000
B65-B83 Helminthiases
0.735 0.265 0.000
N80 Endometriosis
0.733 0.267 0.000
N36.9 Urethral disorder, unspecified
0.732 0.268 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.729 0.271 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.728 0.271 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.728 0.272 0.000
B35-B49 Mycoses
0.726 0.274 0.000
Z90.3 Acquired absence of part of stomach
0.725 0.275 0.000
Z99.2 Dependence on renal dialysis
0.722 0.278 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.720 0.280 0.000
N90.7 Vulvar cyst
0.720 0.280 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.718 0.282 0.000
K86.9 Disease of pancreas, unspecified
0.718 0.282 0.000
B25-B34 Other viral diseases
0.717 0.283 0.000
O30 Multiple gestation
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.715 0.284 0.000
Z89 Acquired absence of limb
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
G80 Infantile cerebral palsy
0.715 0.285 0.000
Z87.0 Personal history of diseases of the respiratory system
0.715 0.285 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.714 0.285 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.714 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.286 0.000
G95 Other diseases of spinal cord
0.714 0.286 0.000
Z90.0 Acquired absence of part of head and neck
0.713 0.287 0.000
N60-N64 Disorders of breast
0.712 0.288 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.712 0.288 0.000
G41 Status epilepticus
0.712 0.288 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.707 0.293 0.000
K82.8 Other specified diseases of gallbladder
0.706 0.294 0.000
N88.2 Stricture and stenosis of cervix uteri
0.706 0.294 0.000
K50 Crohn's disease [regional enteritis]
0.705 0.295 0.000
Z22.5 Carrier of viral hepatitis
0.702 0.298 0.000
Z99.1 Dependence on respirator
0.702 0.298 0.000
N97 Female infertility
0.701 0.299 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.699 0.301 0.000
K37 Unspecified appendicitis
0.699 0.301 0.000
N37 Urethral disorders in diseases classified elsewhere
0.699 0.301 0.000
N34 Urethritis and urethral syndrome
0.699 0.301 0.000
N33 Bladder disorders in diseases classified elsewhere
0.699 0.301 0.000
K86.3 Pseudocyst of pancreas
0.696 0.303 0.000
K80 Cholelithiasis
0.695 0.305 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.693 0.307 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.690 0.310 0.000
G40.8 Other epilepsy
0.689 0.310 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.689 0.310 0.000
G40.5 Special epileptic syndromes
0.689 0.310 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.689 0.310 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.689 0.310 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.689 0.310 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.689 0.311 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.689 0.311 0.000
N30.4 Irradiation cystitis
0.688 0.312 0.000
N30.0 Acute cystitis
0.688 0.312 0.000
K83.1 Obstruction of bile duct
0.688 0.312 0.000
N13 Obstructive and reflux uropathy
0.687 0.313 0.000
Z88.2 Personal history of allergy to sulphonamides
0.684 0.316 0.000
Z94 Transplanted organ and tissue status
0.683 0.317 0.000
N95.2 Postmenopausal atrophic vaginitis
0.683 0.317 0.000
N75 Diseases of Bartholin's gland
0.683 0.317 0.000
Z39 Postpartum care and examination
0.682 0.318 0.000
U88 Agent resistant to multiple antibiotics
0.682 0.318 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.681 0.319 0.000
Z99.4 Dependence on artificial heart
0.681 0.319 0.000
Z99.0 Dependence on aspirator
0.681 0.319 0.000
F30-F39 Mood [affective] disorders
0.680 0.320 0.000
H90-H95 Other disorders of ear
0.679 0.321 0.000
G83 Other paralytic syndromes
0.679 0.321 0.000
A00-A09 Intestinal infectious diseases
0.679 0.321 0.000
O72 Postpartum haemorrhage
0.678 0.322 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.677 0.322 0.000
Z91.7 Personal history of female genital mutilation
0.677 0.322 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.677 0.322 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.677 0.322 0.000
Z91.2 Personal history of poor personal hygiene
0.677 0.322 0.000
Z98 Other postsurgical states
0.675 0.325 0.000
N98 Complications associated with artificial fertilisation
0.675 0.325 0.000
N91 Absent, scanty and rare menstruation
0.675 0.325 0.000
N82 Fistulae involving female genital tract
0.675 0.325 0.000
N96 Habitual aborter
0.675 0.325 0.000
Z90.2 Acquired absence of lung [part of]
0.673 0.327 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.673 0.327 0.000
N89 Other noninflammatory disorders of vagina
0.672 0.328 0.000
G44 Other headache syndromes
0.671 0.329 0.000
O85-O92 Complications predominantly related to the puerperium
0.671 0.329 0.000
K51.9 Ulcerative colitis, unspecified
0.671 0.329 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.670 0.330 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.669 0.331 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.331 0.000
B50-B64 Protozoal diseases
0.669 0.331 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.669 0.331 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.331 0.000
A80-A89 Viral infections of the central nervous system
0.669 0.331 0.000
A75-A79 Rickettsioses
0.669 0.331 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.331 0.000
A65-A69 Other spirochaetal diseases
0.669 0.331 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.669 0.331 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.331 0.000
A15-A19 Tuberculosis
0.669 0.331 0.000
G47.8 Other sleep disorders
0.668 0.332 0.000
G47.4 Narcolepsy and cataplexy
0.668 0.332 0.000
G47.2 Disorders of the sleep-wake schedule
0.668 0.332 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.668 0.332 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.668 0.332 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.667 0.333 0.000
O80-O84 Delivery
0.666 0.333 0.000
O42 Premature rupture of membranes
0.662 0.338 0.000
G62 Other polyneuropathies
0.662 0.338 0.000
K65-K67 Diseases of peritoneum
0.661 0.339 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.661 0.339 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.661 0.339 0.000
G45.3 Amaurosis fugax
0.661 0.339 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.661 0.339 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.661 0.339 0.000
G45.0 Vertebro-basilar artery syndrome
0.661 0.339 0.000
O61 Failed induction of labour
0.660 0.340 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.660 0.340 0.000
N20-N23 Urolithiasis
0.659 0.341 0.000
Z22.3 Carrier of other specified bacterial diseases
0.657 0.343 0.000
N73 Other female pelvic inflammatory diseases
0.656 0.344 0.000
K85 Acute pancreatitis
0.655 0.345 0.000
N87 Dysplasia of cervix uteri
0.655 0.345 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.654 0.346 0.000
N85.4 Malposition of uterus
0.654 0.346 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.652 0.348 0.000
Z28 Immunisation not carried out
0.650 0.350 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.650 0.350 0.000
Z26 Need for immunisation against other single infectious diseases
0.650 0.350 0.000
Z25 Need for immunisation against other single viral diseases
0.650 0.350 0.000
Z24 Need for immunisation against certain single viral diseases
0.650 0.350 0.000
Z23 Need for immunisation against single bacterial diseases
0.650 0.350 0.000
Z20 Contact with and exposure to communicable diseases
0.650 0.350 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.650 0.350 0.000
K81 Cholecystitis
0.650 0.350 0.000
Z91.6 Personal history of other physical trauma
0.645 0.355 0.000
O36 Maternal care for other known or suspected foetal problems
0.644 0.356 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.643 0.357 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.642 0.358 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.642 0.358 0.000
N83.7 Haematoma of broad ligament
0.642 0.358 0.000
N83.6 Haematosalpinx
0.642 0.358 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.642 0.358 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.642 0.358 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.642 0.358 0.000
K86.2 Cyst of pancreas
0.641 0.359 0.000
K86.8 Other specified diseases of pancreas
0.639 0.361 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.639 0.361 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.638 0.362 0.000
H80-H83 Diseases of inner ear
0.638 0.362 0.000
S90-S99 Injuries to the ankle and foot
0.638 0.362 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.637 0.362 0.000
K83.9 Disease of biliary tract, unspecified
0.636 0.363 0.000
K83.5 Biliary cyst
0.636 0.363 0.000
K83.4 Spasm of sphincter of Oddi
0.636 0.363 0.000
K83.3 Fistula of bile duct
0.636 0.363 0.000
K83.2 Perforation of bile duct
0.636 0.363 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.636 0.364 0.000
N36.3 Prolapsed urethral mucosa
0.633 0.367 0.000
N36.1 Urethral diverticulum
0.633 0.367 0.000
N36.0 Urethral fistula
0.633 0.367 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.633 0.367 0.000
K82.9 Disease of gallbladder, unspecified
0.633 0.367 0.000
K82.3 Fistula of gallbladder
0.633 0.367 0.000
K82.2 Perforation of gallbladder
0.633 0.367 0.000
K82.1 Hydrops of gallbladder
0.633 0.367 0.000
K82.0 Obstruction of gallbladder
0.633 0.367 0.000
G60 Hereditary and idiopathic neuropathy
0.632 0.368 0.000
G93.2 Benign intracranial hypertension
0.631 0.369 0.000
K70 Alcoholic liver disease
0.631 0.369 0.000
Z97.8 Presence of other specified devices
0.630 0.370 0.000
G50 Disorders of trigeminal nerve
0.630 0.370 0.000
N36.2 Urethral caruncle
0.630 0.370 0.000
K38 Other diseases of appendix
0.627 0.373 0.000
K36 Other appendicitis
0.627 0.373 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.626 0.374 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.624 0.376 0.000
K40-K46 Hernia
0.623 0.377 0.000
S70-S79 Injuries to the hip and thigh
0.623 0.377 0.000
N64 Other disorders of breast
0.623 0.377 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.623 0.377 0.000
K76 Other diseases of liver
0.622 0.378 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.621 0.379 0.000
G81.1 Spastic hemiplegia
0.620 0.380 0.000
G81.0 Flaccid hemiplegia
0.620 0.380 0.000
K75 Other inflammatory liver diseases
0.618 0.381 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.618 0.381 0.000
S40-S49 Injuries to the shoulder and upper arm
0.618 0.382 0.000
K50.9 Crohn's disease, unspecified
0.618 0.382 0.000
N72 Inflammatory disease of cervix uteri
0.618 0.382 0.000
O45 Premature separation of placenta [abruptio placentae]
0.618 0.382 0.000
O44 Placenta praevia
0.618 0.382 0.000
O43 Placental disorders
0.618 0.382 0.000
O41 Other disorders of amniotic fluid and membranes
0.618 0.382 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.618 0.382 0.000
O33 Maternal care for known or suspected disproportion
0.618 0.382 0.000
O31 Complications specific to multiple gestation
0.618 0.382 0.000
O40 Polyhydramnios
0.618 0.382 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.617 0.383 0.000
Z87.8 Personal history of other specified conditions
0.616 0.384 0.000
K74 Fibrosis and cirrhosis of liver
0.615 0.385 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.615 0.385 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.615 0.385 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.615 0.385 0.000
G96 Other disorders of central nervous system
0.615 0.385 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.615 0.385 0.000
G90 Disorders of autonomic nervous system
0.615 0.385 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.615 0.385 0.000
G92 Toxic encephalopathy
0.615 0.385 0.000
F32 Depressive episode
0.614 0.386 0.000
N00-N08 Glomerular diseases
0.613 0.386 0.000
O30.0 Twin pregnancy
0.613 0.387 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.613 0.387 0.000
K35.8 Acute appendicitis, other and unspecified
0.612 0.388 0.000
O48 Prolonged pregnancy
0.612 0.388 0.000
G58 Other mononeuropathies
0.610 0.390 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.610 0.390 0.000
G91 Hydrocephalus
0.610 0.390 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.609 0.391 0.000
Z29.0 Isolation
0.609 0.391 0.000
Z37 Outcome of delivery
0.608 0.392 0.000
O20 Haemorrhage in early pregnancy
0.608 0.392 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.607 0.392 0.000
N90.6 Hypertrophy of vulva
0.607 0.392 0.000
N90.3 Dysplasia of vulva, unspecified
0.607 0.392 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.607 0.392 0.000
N90.1 Moderate vulvar dysplasia
0.607 0.392 0.000
N90.0 Mild vulvar dysplasia
0.607 0.392 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.607 0.393 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.607 0.393 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.607 0.393 0.000
G82.2 Paraplegia, unspecified
0.607 0.393 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.606 0.394 0.000
Z93 Artificial opening status
0.604 0.395 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.601 0.399 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.601 0.399 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.600 0.400 0.000
K35.9 Acute appendicitis, unspecified
0.600 0.400 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.599 0.401 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.599 0.401 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.599 0.401 0.000
Z98.8 Other specified postsurgical states
0.599 0.401 0.000
N90.4 Leukoplakia of vulva
0.599 0.401 0.000
Z39.0 Care and examination immediately after delivery
0.597 0.403 0.000
O47.0 False labour before 37 completed weeks of gestation
0.597 0.403 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.597 0.403 0.000
O74 Complications of anaesthesia during labour and delivery
0.597 0.403 0.000
O73 Retained placenta and membranes, without haemorrhage
0.597 0.403 0.000
O71 Other obstetric trauma
0.597 0.403 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.597 0.403 0.000
O66 Other obstructed labour
0.597 0.403 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.597 0.403 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.597 0.403 0.000
O62 Abnormalities of forces of labour
0.597 0.403 0.000
O60 Preterm delivery
0.597 0.403 0.000
A30-A49 Other bacterial diseases
0.596 0.404 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.594 0.406 0.000
N76 Other inflammation of vagina and vulva
0.594 0.406 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.594 0.406 0.000
N71 Inflammatory disease of uterus, except cervix
0.594 0.406 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.594 0.406 0.000
G95.8 Other specified diseases of spinal cord
0.594 0.406 0.000
B80 Enterobiasis
0.593 0.407 0.000
N25-N29 Other disorders of kidney and ureter
0.593 0.407 0.000
N32.8 Other specified disorders of bladder
0.593 0.407 0.000
S20-S29 Injuries to the thorax
0.592 0.408 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.590 0.409 0.000
N15 Other renal tubulo-interstitial diseases
0.590 0.409 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.590 0.409 0.000
N11 Chronic tubulo-interstitial nephritis
0.590 0.409 0.000
N10 Acute tubulo-interstitial nephritis
0.590 0.409 0.000
N85.7 Haematometra
0.590 0.410 0.000
N85.6 Intra-uterine synechiae
0.590 0.410 0.000
N85.5 Inversion of uterus
0.590 0.410 0.000
N85.3 Subinvolution of uterus
0.590 0.410 0.000
N85.1 Endometrial adenomatous hyperplasia
0.590 0.410 0.000
O00-O08 Pregnancy with abortive outcome
0.589 0.411 0.000
K42 Umbilical hernia
0.588 0.412 0.000
Z88.5 Personal history of allergy to narcotic agent
0.588 0.412 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.588 0.412 0.000
Q60-Q64 Congenital malformations of the urinary system
0.586 0.414 0.000
N95.1 Menopausal and female climacteric states
0.585 0.415 0.000
Z39.1 Care and examination of lactating mother
0.584 0.416 0.000
Z35 Supervision of high-risk pregnancy
0.584 0.416 0.000
F60-F69 Disorders of adult personality and behaviour
0.583 0.417 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.582 0.418 0.000
K77 Liver disorders in diseases classified elsewhere
0.582 0.418 0.000
K73 Chronic hepatitis, not elsewhere classified
0.582 0.418 0.000
K71 Toxic liver disease
0.582 0.418 0.000
F99-F99 Unspecified mental disorder
0.582 0.418 0.000
Z29.8 Other specified prophylactic measures
0.580 0.419 0.000
Z22.9 Carrier of infectious disease, unspecified
0.580 0.420 0.000
Z22.8 Carrier of other infectious diseases
0.580 0.420 0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection
0.580 0.420 0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission
0.580 0.420 0.000
Z22.2 Carrier of diphtheria
0.580 0.420 0.000
Z22.1 Carrier of other intestinal infectious diseases
0.580 0.420 0.000
Z22.0 Carrier of typhoid
0.580 0.420 0.000
G61 Inflammatory polyneuropathy
0.579 0.421 0.000
G64 Other disorders of peripheral nervous system
0.579 0.421 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.579 0.421 0.000
N75.1 Abscess of Bartholin's gland
0.579 0.421 0.000
O21 Excessive vomiting in pregnancy
0.577 0.423 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.577 0.423 0.000
B37 Candidiasis
0.577 0.423 0.000
Z97.4 Presence of external hearing-aid
0.576 0.423 0.000
S00-S09 Injuries to the head
0.575 0.425 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.575 0.425 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.575 0.425 0.000
K80.8 Other cholelithiasis
0.573 0.427 0.000
T79-T79 Certain early complications of trauma
0.573 0.427 0.000
T33-T35 Frostbite
0.573 0.427 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.573 0.427 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.573 0.427 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.573 0.427 0.000
T00-T07 Injuries involving multiple body regions
0.573 0.427 0.000
S10-S19 Injuries to the neck
0.573 0.427 0.000
Q50-Q56 Congenital malformations of genital organs
0.572 0.427 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.571 0.428 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.571 0.428 0.000
N88.3 Incompetence of cervix uteri
0.571 0.428 0.000
N88.1 Old laceration of cervix uteri
0.571 0.428 0.000
N88.0 Leukoplakia of cervix uteri
0.571 0.428 0.000
F32.9 Depressive episode, unspecified
0.569 0.431 0.000
O72.1 Other immediate postpartum haemorrhage
0.567 0.433 0.000
G93.6 Cerebral oedema
0.566 0.434 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.565 0.435 0.000
A08 Viral and other specified intestinal infections
0.565 0.435 0.000
K35.3 Acute appendicitis with localized peritonitis
0.564 0.436 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.563 0.437 0.000
Z91.5 Personal history of self-harm
0.563 0.437 0.000
S50-S59 Injuries to the elbow and forearm
0.563 0.437 0.000
G93.8 Other specified disorders of brain
0.563 0.437 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.562 0.438 0.000
B34 Viral infection of unspecified site
0.562 0.438 0.000
K51.2 Ulcerative (chronic) proctitis
0.562 0.438 0.000
N17-N19 Renal failure
0.560 0.440 0.000
N80.2 Endometriosis of Fallopian tube
0.559 0.441 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.559 0.441 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.559 0.441 0.000
G47.9 Sleep disorder, unspecified
0.558 0.442 0.000
K72 Hepatic failure, not elsewhere classified
0.558 0.442 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.558 0.442 0.000
G62.9 Polyneuropathy, unspecified
0.557 0.443 0.000
T86 Failure and rejection of transplanted organs and tissues
0.556 0.443 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.556 0.443 0.000
O70 Perineal laceration during delivery
0.556 0.444 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.556 0.444 0.000
N80.9 Endometriosis, unspecified
0.556 0.444 0.000
G80.9 Infantile cerebral palsy, unspecified
0.555 0.444 0.000
Z83.7 Family history of diseases of the digestive system
0.554 0.446 0.000
N80.1 Endometriosis of ovary
0.554 0.446 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.553 0.447 0.000
F80-F89 Disorders of psychological development
0.553 0.447 0.000
F70-F79 Mental retardation
0.553 0.447 0.000
Z97.3 Presence of spectacles and contact lenses
0.553 0.447 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.553 0.447 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.553 0.447 0.000
Z97.0 Presence of artificial eye
0.553 0.447 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.553 0.447 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.553 0.447 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.552 0.448 0.000
N95.3 States associated with artificial menopause
0.552 0.448 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.551 0.449 0.000
G50.0 Trigeminal neuralgia
0.551 0.449 0.000
K51.5 Mucosal proctocolitis
0.551 0.449 0.000
K51.4 Pseudopolyposis of colon
0.551 0.449 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.551 0.449 0.000
K90 Intestinal malabsorption
0.551 0.449 0.000
K91.4 Colostomy and enterostomy malfunction
0.551 0.449 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.550 0.450 0.000
Q80-Q89 Other congenital malformations
0.550 0.450 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.550 0.450 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.550 0.450 0.000
Q35-Q37 Cleft lip and cleft palate
0.550 0.450 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.550 0.450 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.550 0.450 0.000
Q00-Q07 Congenital malformations of the nervous system
0.550 0.450 0.000
N85.2 Hypertrophy of uterus
0.550 0.450 0.000
H92 Otalgia and effusion of ear
0.549 0.451 0.000
N92 Excessive, frequent and irregular menstruation
0.549 0.451 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.548 0.452 0.000
N70 Salpingitis and oophoritis
0.547 0.453 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.547 0.453 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.546 0.454 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.545 0.455 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.544 0.456 0.000
Z94.4 Liver transplant status
0.543 0.456 0.000
U89 Agent resistant to other and unspecified antibiotics
0.543 0.457 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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