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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7744020
log Bayes Factor = 93.1961
Chromosome 6   position 32,626,130  (GRCh37) Explore rs7744020 on Ensembl!
Variant rs7744020 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
N48 Other disorders of penis
1.000 0.000 0.000
N47 Redundant prepuce, phimosis and paraphimosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
N48.6 Balanitis xerotica obliterans
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
N40-N51 Diseases of male genital organs
0.997 0.003 0.000
E10.2 With renal complications
0.000 0.004 0.996
H36.0 Diabetic retinopathy
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.000 0.015 0.985
N48.0 Leukoplakia of penis
0.981 0.019 0.000
E10.5 With peripheral circulatory complications
0.000 0.026 0.974
N48.1 Balanoposthitis
0.963 0.037 0.000
E14.3 With ophthalmic complications
0.000 0.052 0.948
N48.2 Other inflammatory disorders of penis
0.926 0.074 0.000
D07.1 Vulva
0.913 0.087 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.908 0.092 0.000
D00-D09 In situ neoplasms
0.903 0.097 0.000
D06 Carcinoma in situ of cervix uteri
0.892 0.108 0.000
N90.4 Leukoplakia of vulva
0.890 0.110 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.889 0.111 0.000
D06.9 Cervix, unspecified
0.878 0.122 0.000
N90.7 Vulvar cyst
0.865 0.135 0.000
N48.8 Other specified disorders of penis
0.853 0.147 0.000
E50-E64 Other nutritional deficiencies
0.000 0.150 0.850
N45 Orchitis and epididymitis
0.849 0.151 0.000
D04 Carcinoma in situ of skin
0.846 0.154 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.156 0.844
D07.4 Penis
0.841 0.159 0.000
E10.0 With coma
0.000 0.174 0.826
E10.8 With unspecified complications
0.000 0.180 0.820
E14.9 Without complications
0.000 0.187 0.813
N48.5 Ulcer of penis
0.812 0.188 0.000
N90.3 Dysplasia of vulva, unspecified
0.810 0.190 0.000
E55 Vitamin D deficiency
0.000 0.190 0.810
N42 Other disorders of prostate
0.808 0.192 0.000
N44 Torsion of testis
0.807 0.193 0.000
E27 Other disorders of adrenal gland
0.000 0.194 0.806
D04.7 Skin of lower limb, including hip
0.802 0.198 0.000
E40-E46 Malnutrition
0.000 0.204 0.796
N48.9 Disorder of penis, unspecified
0.795 0.205 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.207 0.793
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.793 0.207 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.786 0.214 0.000
E14.6 With other specified complications
0.000 0.219 0.781
E55.9 Vitamin D deficiency, unspecified
0.000 0.219 0.781
E14.8 With unspecified complications
0.000 0.222 0.778
D04.9 Skin, unspecified
0.774 0.226 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.772 0.228 0.000
N90.1 Moderate vulvar dysplasia
0.764 0.236 0.000
E10.6 With other specified complications
0.000 0.240 0.760
N48.3 Priapism
0.756 0.244 0.000
D03 Melanoma in situ
0.755 0.245 0.000
N42.9 Disorder of prostate, unspecified
0.750 0.250 0.000
N90.6 Hypertrophy of vulva
0.747 0.253 0.000
E14.5 With peripheral circulatory complications
0.000 0.256 0.744
E14.2 Withrenal complications
0.000 0.262 0.738
E14.1 With ketoacidosis
0.000 0.265 0.734
N48.4 Impotence of organic origin
0.733 0.267 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.727 0.273 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.274 0.726
E34 Other endocrine disorders
0.000 0.274 0.726
D06.1 Exocervix
0.723 0.277 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.723 0.277 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.721 0.279 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.715
D09 Carcinoma in situ of other and unspecified sites
0.711 0.289 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.706 0.294 0.000
E14.7 With multiple complications
0.000 0.294 0.706
E14.0 With coma
0.000 0.294 0.706
D07.2 Vagina
0.699 0.301 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.687 0.313 0.000
D04.4 Skin of scalp and neck
0.685 0.315 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.683 0.317 0.000
D01.3 Anus and anal canal
0.679 0.321 0.000
E28 Ovarian dysfunction
0.000 0.322 0.678
D06.0 Endocervix
0.675 0.325 0.000
N90.0 Mild vulvar dysplasia
0.673 0.327 0.000
E00-E07 Disorders of thyroid gland
0.018 0.333 0.649
E46 Unspecified protein-energy malnutrition
0.000 0.348 0.652
E23.7 Disorder of pituitary gland, unspecified
0.000 0.349 0.651
D07.6 Other and unspecified male genital organs
0.651 0.349 0.000
D07.3 Other and unspecified female genital organs
0.651 0.349 0.000
D07.0 Endometrium
0.651 0.349 0.000
E03 Other hypothyroidism
0.448 0.350 0.202
E51 Thiamine deficiency
0.000 0.352 0.648
E14.4 With neurological complications
0.000 0.356 0.644
N42.2 Atrophy of prostate
0.641 0.359 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.640 0.360 0.000
D06.7 Other parts of cervix
0.639 0.361 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.638 0.362 0.000
N41 Inflammatory diseases of prostate
0.628 0.372 0.000
D09.1 Other and unspecified urinary organs
0.623 0.377 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.378 0.622
D04.3 Skin of other and unspecified parts of face
0.619 0.381 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.390 0.609
E63 Other nutritional deficiencies
0.000 0.390 0.609
E50 Vitamin A deficiency
0.000 0.390 0.609
E60 Dietary zinc deficiency
0.000 0.390 0.609
E59 Dietary selenium deficiency
0.000 0.390 0.609
E54 Ascorbic acid deficiency
0.000 0.390 0.609
E52 Niacin deficiency [pellagra]
0.000 0.390 0.609
D04.8 Skin of other sites
0.607 0.393 0.000
D04.0 Skin of lip
0.607 0.393 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.395 0.605
E32 Diseases of thymus
0.000 0.395 0.605
E31 Polyglandular dysfunction
0.000 0.395 0.605
E30 Disorders of puberty, not elsewhere classified
0.000 0.395 0.605
D03.8 Melanoma in situ of other sites
0.595 0.405 0.000
N42.1 Congestion and haemorrhage of prostate
0.590 0.410 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.004 0.416 0.580
E55.0 Rickets, active
0.000 0.419 0.581
N42.3 Dysplasia of prostate
0.580 0.420 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.422 0.578
E27.0 Other adrenocortical overactivity
0.000 0.422 0.578
E23.6 Other disorders of pituitary gland
0.000 0.425 0.575
L90.0 Lichen sclerosus et atrophicus
0.573 0.427 0.000
E22 Hyperfunction of pituitary gland
0.000 0.427 0.573
E34.8 Other specified endocrine disorders
0.000 0.428 0.572
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.429 0.571
E45 Retarded development following protein-energy malnutrition
0.000 0.429 0.571
E43 Unspecified severe protein-energy malnutrition
0.000 0.429 0.571
E42 Marasmic kwashiorkor
0.000 0.429 0.571
E41 Nutritional marasmus
0.000 0.429 0.571
E40 Kwashiorkor
0.000 0.429 0.571
E56 Other vitamin deficiencies
0.000 0.433 0.567
E27.9 Disorder of adrenal gland, unspecified
0.000 0.434 0.566
E20 Hypoparathyroidism
0.000 0.440 0.560
N46 Male infertility
0.557 0.443 0.000
D04.1 Skin of eyelid, including canthus
0.556 0.444 0.000
D01.0 Colon
0.554 0.446 0.000
D01.9 Digestive organ, unspecified
0.554 0.446 0.000
D01.7 Other specified digestive organs
0.554 0.446 0.000
D01.5 Liver, gallbladder and bile ducts
0.554 0.446 0.000
D01.4 Other and unspecified parts of intestine
0.554 0.446 0.000
D01.2 Rectum
0.554 0.446 0.000
D01.1 Rectosigmoid junction
0.554 0.446 0.000
E16.1 Other hypoglycaemia
0.000 0.447 0.552
E58 Dietary calcium deficiency
0.000 0.449 0.551
E25 Adrenogenital disorders
0.000 0.449 0.551
J45 Asthma
0.548 0.452 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.452 0.548
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.455 0.545
E29 Testicular dysfunction
0.000 0.456 0.544
D04.5 Skin of trunk
0.541 0.459 0.000
D03.9 Melanoma in situ, unspecified
0.541 0.459 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.541 0.459 0.000
D03.0 Melanoma in situ of lip
0.541 0.459 0.000
E23.0 Hypopituitarism
0.000 0.462 0.538
H36 Retinal disorders in diseases classified elsewhere
0.000 0.463 0.537
D00.0 Lip, oral cavity and pharynx
0.536 0.464 0.000
E26 Hyperaldosteronism
0.000 0.465 0.535
D03.7 Melanoma in situ of lower limb, including hip
0.534 0.466 0.000
N49.2 Inflammatory disorders of scrotum
0.530 0.470 0.000
E61 Deficiency of other nutrient elements
0.000 0.471 0.529
E34.5 Androgen resistance syndrome
0.000 0.479 0.520
E34.4 Constitutional tall stature
0.000 0.479 0.520
E34.3 Short stature, not elsewhere classified
0.000 0.479 0.520
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.479 0.520
E34.1 Other hypersecretion of intestinal hormones
0.000 0.479 0.520
N49.9 Inflammatory disorder of unspecified male genital organ
0.518 0.482 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.518 0.482 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.518 0.482 0.000
N41.1 Chronic prostatitis
0.518 0.482 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.483 0.517
E23.1 Drug-induced hypopituitarism
0.000 0.483 0.517
D02.2 Bronchus and lung
0.516 0.484 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.514 0.486 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
D02.0 Larynx
0.510 0.490 0.000
D09.9 Carcinoma in situ, unspecified
0.510 0.490 0.000
D09.7 Carcinoma in situ of other specified sites
0.510 0.490 0.000
D09.3 Thyroid and other endocrine glands
0.510 0.490 0.000
D09.2 Eye
0.510 0.490 0.000
D03.5 Melanoma in situ of trunk
0.509 0.491 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.506 0.493 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.506 0.493 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.506 0.493 0.000
E28.3 Primary ovarian failure
0.000 0.496 0.504
E51.2 Wernicke's encephalopathy
0.000 0.496 0.504
E34.0 Carcinoid syndrome
0.000 0.497 0.503
N51.2 Balanitis in diseases classified elsewhere
0.498 0.502 0.000
D02.4 Respiratory system, unspecified
0.492 0.508 0.000
D02.3 Other parts of respiratory system
0.492 0.508 0.000
D02.1 Trachea
0.492 0.508 0.000
D00.2 Stomach
0.490 0.510 0.000
E83.1 Disorders of iron metabolism
0.000 0.511 0.489
E28.9 Ovarian dysfunction, unspecified
0.000 0.514 0.486
E28.8 Other ovarian dysfunction
0.000 0.514 0.486
E28.1 Androgen excess
0.000 0.514 0.486
E28.0 Oestrogen excess
0.000 0.514 0.486
E83 Disorders of mineral metabolism
0.000 0.518 0.482
E70-E90 Metabolic disorders
0.000 0.518 0.482
E02 Subclinical iodine-deficiency hypothyroidism
0.012 0.520 0.468
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.013 0.522 0.465
E00 Congenital iodine-deficiency syndrome
0.013 0.522 0.465
E13 Other specified diabetes mellitus
0.000 0.522 0.478
E22.0 Acromegaly and pituitary gigantism
0.000 0.523 0.477
D00.1 Oesophagus
0.476 0.524 0.000
D04.2 Skin of ear and external auricular canal
0.468 0.532 0.000
E03.5 Myxoedema coma
0.322 0.534 0.145
E03.4 Atrophy of thyroid (acquired)
0.322 0.534 0.145
E03.3 Postinfectious hypothyroidism
0.322 0.534 0.145
E03.0 Congenital hypothyroidism with diffuse goitre
0.322 0.534 0.145
E05.9 Thyrotoxicosis, unspecified
0.000 0.534 0.466
E51.9 Thiamine deficiency, unspecified
0.000 0.535 0.465
E51.8 Other manifestations of thiamine deficiency
0.000 0.535 0.465
E51.1 Beriberi
0.000 0.535 0.465
E53 Deficiency of other B group vitamins
0.000 0.535 0.465
D03.6 Melanoma in situ of upper limb, including shoulder
0.461 0.539 0.000
N42.8 Other specified disorders of prostate
0.457 0.543 0.000
N41.8 Other inflammatory diseases of prostate
0.456 0.544 0.000
E27.2 Addisonian crisis
0.000 0.546 0.453
N41.3 Prostatocystitis
0.450 0.549 0.000
N41.2 Abscess of prostate
0.450 0.549 0.000
E03.1 Congenital hypothyroidism without goitre
0.303 0.550 0.148
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.306 0.558 0.136
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.559 0.441
E03.8 Other specified hypothyroidism
0.332 0.559 0.109
E50.9 Vitamin A deficiency, unspecified
0.000 0.563 0.437
E50.8 Other manifestations of vitamin A deficiency
0.000 0.563 0.437
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.563 0.437
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.563 0.437
E50.5 Vitamin A deficiency with night blindness
0.000 0.563 0.437
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.563 0.437
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.563 0.437
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.563 0.437
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.563 0.437
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.563 0.437
E63.9 Nutritional deficiency, unspecified
0.000 0.563 0.437
E63.8 Other specified nutritional deficiencies
0.000 0.563 0.437
E63.1 Imbalance of constituents of food intake
0.000 0.563 0.437
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.563 0.437
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.563 0.437
E64.8 Sequelae of other nutritional deficiencies
0.000 0.563 0.437
E64.3 Sequelae of rickets
0.000 0.563 0.437
E64.2 Sequelae of vitamin C deficiency
0.000 0.563 0.437
E64.1 Sequelae of vitamin A deficiency
0.000 0.563 0.437
E64.0 Sequelae of protein-energy malnutrition
0.000 0.563 0.437
J45.0 Predominantly allergic asthma
0.437 0.563 0.000
E07 Other disorders of thyroid
0.013 0.564 0.423
E30.9 Disorder of puberty, unspecified
0.000 0.566 0.434
E30.8 Other disorders of puberty
0.000 0.566 0.434
E30.1 Precocious puberty
0.000 0.566 0.434
E30.0 Delayed puberty
0.000 0.566 0.434
E31.9 Polyglandular dysfunction, unspecified
0.000 0.566 0.434
E31.8 Other polyglandular dysfunction
0.000 0.566 0.434
E31.1 Polyglandular hyperfunction
0.000 0.566 0.434
E31.0 Autoimmune polyglandular failure
0.000 0.566 0.434
E32.9 Disease of thymus, unspecified
0.000 0.566 0.434
E32.8 Other diseases of thymus
0.000 0.566 0.434
E32.1 Abscess of thymus
0.000 0.566 0.434
E32.0 Persistent hyperplasia of thymus
0.000 0.566 0.434
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.566 0.434
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.566 0.434
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.566 0.434
E06 Thyroiditis
0.009 0.577 0.414
E83.4 Disorders of magnesium metabolism
0.000 0.580 0.420
E05.5 Thyroid crisis or storm
0.003 0.581 0.416
E05.4 Thyrotoxicosis factitia
0.003 0.581 0.416
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.003 0.581 0.416
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.003 0.581 0.416
K90 Intestinal malabsorption
0.000 0.586 0.414
J45.1 Nonallergic asthma
0.413 0.587 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.413 0.587 0.000
D03.4 Melanoma in situ of scalp and neck
0.411 0.589 0.000
E61.2 Magnesium deficiency
0.000 0.589 0.411
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.589 0.411
E22.8 Other hyperfunction of pituitary gland
0.000 0.589 0.411
E44.1 Mild protein-energy malnutrition
0.000 0.590 0.409
E44.0 Moderate protein-energy malnutrition
0.000 0.590 0.409
C21.0 Anus, unspecified
0.407 0.593 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.593 0.406
E56.8 Deficiency of other vitamins
0.000 0.593 0.406
E56.0 Deficiency of vitamin E
0.000 0.593 0.406
E20.8 Other hypoparathyroidism
0.000 0.598 0.401
E20.1 Pseudohypoparathyroidism
0.000 0.598 0.401
E20.0 Idiopathic hypoparathyroidism
0.000 0.598 0.401
J45.8 Mixed asthma
0.401 0.599 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.599 0.401
D09.0 Bladder
0.397 0.603 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.605 0.395
E25.8 Other adrenogenital disorders
0.000 0.605 0.395
C21 Malignant neoplasm of anus and anal canal
0.395 0.605 0.000
C21.1 Anal canal
0.394 0.606 0.000
E29.8 Other testicular dysfunction
0.000 0.610 0.390
E29.0 Testicular hyperfunction
0.000 0.610 0.390
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.002 0.615 0.383
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.615 0.385
N41.0 Acute prostatitis
0.385 0.615 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.616 0.384
E26.8 Other hyperaldosteronism
0.000 0.616 0.384
E26.1 Secondary hyperaldosteronism
0.000 0.616 0.384
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.620 0.380
E61.9 Deficiency of nutrient element, unspecified
0.000 0.621 0.379
E61.8 Deficiency of other specified nutrient elements
0.000 0.621 0.379
E61.7 Deficiency of multiple nutrient elements
0.000 0.621 0.379
E61.6 Vanadium deficiency
0.000 0.621 0.379
E61.5 Molybdenum deficiency
0.000 0.621 0.379
E61.4 Chromium deficiency
0.000 0.621 0.379
E61.3 Manganese deficiency
0.000 0.621 0.379
E61.0 Copper deficiency
0.000 0.621 0.379
N90.5 Atrophy of vulva
0.378 0.622 0.000
D04.6 Skin of upper limb, including shoulder
0.378 0.622 0.000
E22.1 Hyperprolactinaemia
0.000 0.624 0.375
E07.8 Other specified disorders of thyroid
0.005 0.625 0.369
E29.1 Testicular hypofunction
0.000 0.628 0.372
E79 Disorders of purine and pyrimidine metabolism
0.000 0.635 0.365
E56.1 Deficiency of vitamin K
0.000 0.636 0.364
E65-E68 Obesity and other hyperalimentation
0.000 0.636 0.364
R31 Unspecified haematuria
0.363 0.637 0.000
N43 Hydrocele and spermatocele
0.360 0.639 0.000
E84 Cystic fibrosis
0.000 0.643 0.357
E20.9 Hypoparathyroidism, unspecified
0.000 0.644 0.356
E73 Lactose intolerance
0.000 0.644 0.356
E29.9 Testicular dysfunction, unspecified
0.000 0.648 0.351
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.649 0.351
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.654 0.346
E83.8 Other disorders of mineral metabolism
0.000 0.654 0.346
E83.2 Disorders of zinc metabolism
0.000 0.654 0.346
E83.0 Disorders of copper metabolism
0.000 0.654 0.346
E77 Disorders of glycoprotein metabolism
0.000 0.655 0.345
E76 Disorders of glycosaminoglycan metabolism
0.000 0.655 0.345
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.655 0.345
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.655 0.345
E53.9 Vitamin B deficiency, unspecified
0.000 0.656 0.344
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.009 0.657 0.334
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.009 0.657 0.334
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.009 0.657 0.334
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.009 0.657 0.334
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.009 0.657 0.334
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.009 0.657 0.334
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.009 0.657 0.334
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.009 0.657 0.334
E13.8 With unspecified complications
0.000 0.657 0.342
E13.7 With multiple complications
0.000 0.657 0.342
E13.6 With other specified complications
0.000 0.657 0.342
E13.5 With peripheral circulatory complications
0.000 0.657 0.342
E13.4 With neurological complications
0.000 0.657 0.342
E13.2 With renal complications
0.000 0.657 0.342
E13.1 With ketoacidosis
0.000 0.657 0.342
E13.0 With coma
0.000 0.657 0.342
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.659 0.341
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.660 0.340
E88 Other metabolic disorders
0.000 0.662 0.338
E53.1 Pyridoxine deficiency
0.000 0.666 0.333
E53.0 Riboflavin deficiency
0.000 0.666 0.333
G37 Other demyelinating diseases of central nervous system
0.000 0.672 0.328
E72 Other disorders of amino-acid metabolism
0.000 0.672 0.328
E04 Other non-toxic goitre
0.002 0.672 0.325
E06.9 Thyroiditis, unspecified
0.005 0.673 0.323
E11 Non-insulin-dependent diabetes mellitus
0.000 0.679 0.321
E70 Disorders of aromatic amino-acid metabolism
0.000 0.681 0.319
N42.0 Calculus of prostate
0.316 0.683 0.001
E23.2 Diabetes insipidus
0.000 0.683 0.316
G36 Other acute disseminated demyelination
0.000 0.683 0.316
C21.8 Overlapping lesion of rectum, anus and anal canal
0.316 0.684 0.000
E24 Cushing's syndrome
0.001 0.686 0.313
E26.0 Primary hyperaldosteronism
0.000 0.686 0.314
E13.3 With ophthalmic complications
0.000 0.687 0.312
E07.1 Dyshormogenetic goitre
0.010 0.687 0.303
E07.0 Hypersecretion of calcitonin
0.010 0.687 0.303
E89.0 Postprocedural hypothyroidism
0.000 0.691 0.309
E05.8 Other thyrotoxicosis
0.003 0.691 0.305
N41.9 Inflammatory disease of prostate, unspecified
0.308 0.692 0.000
E06.4 Drug-induced thyroiditis
0.007 0.697 0.297
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.007 0.697 0.297
E06.1 Subacute thyroiditis
0.007 0.697 0.297
E06.0 Acute thyroiditis
0.007 0.697 0.297
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.697 0.303
E89.3 Postprocedural hypopituitarism
0.000 0.700 0.300
K90.3 Pancreatic steatorrhoea
0.000 0.703 0.297
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.703 0.297
K90.1 Tropical sprue
0.000 0.703 0.297
K90.8 Other intestinal malabsorption
0.000 0.708 0.292
E88.8 Other specified metabolic disorders
0.000 0.716 0.284
E74 Other disorders of carbohydrate metabolism
0.000 0.716 0.284
C21.2 Cloacogenic zone
0.283 0.717 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.718 0.282
E83.5 Disorders of calcium metabolism
0.000 0.722 0.278
E06.5 Other chronic thyroiditis
0.007 0.722 0.271
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.723 0.277
E04.0 Non-toxic diffuse goitre
0.001 0.725 0.274
E84.9 Cystic fibrosis, unspecified
0.000 0.732 0.268
E11.1 With ketoacidosis
0.000 0.732 0.268
E89.4 Postprocedural ovarian failure
0.000 0.734 0.266
E73.9 Lactose intolerance, unspecified
0.000 0.735 0.265
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.736 0.264
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.738 0.262
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.738 0.262
E79.1 Lesch-Nyhan syndrome
0.000 0.738 0.262
N43.2 Other hydrocele
0.261 0.739 0.000
E67 Other hyperalimentation
0.000 0.739 0.261
E68 Sequelae of hyperalimentation
0.000 0.739 0.261
N43.1 Infected hydrocele
0.261 0.739 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.740 0.260
N43.0 Encysted hydrocele
0.259 0.741 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.744 0.256
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.744 0.256
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.744 0.256
E73.8 Other lactose intolerance
0.000 0.745 0.255
E73.1 Secondary lactase deficiency
0.000 0.745 0.255
E73.0 Congenital lactase deficiency
0.000 0.745 0.255
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.747 0.253
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.748 0.252
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.748 0.252
E89.1 Postprocedural hypoinsulinaemia
0.000 0.748 0.252
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.748 0.252
L90 Atrophic disorders of skin
0.249 0.751 0.000
E11.3 With ophthalmic complications
0.000 0.751 0.249
E71.3 Disorders of fatty-acid metabolism
0.000 0.752 0.248
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.752 0.248
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.752 0.248
E71.0 Maple-syrup-urine disease
0.000 0.752 0.248
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.752 0.248
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.752 0.248
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.752 0.248
E76.2 Other mucopolysaccharidoses
0.000 0.752 0.248
E76.1 Mucopolysaccharidosis, type II
0.000 0.752 0.248
E76.0 Mucopolysaccharidosis, type I
0.000 0.752 0.248
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.752 0.248
E77.8 Other disorders of glycoprotein metabolism
0.000 0.752 0.248
E77.1 Defects in glycoprotein degradation
0.000 0.752 0.248
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.752 0.248
E87.7 Fluid overload
0.000 0.756 0.244
E06.3 Autoimmune thyroiditis
0.004 0.758 0.238
E04.9 Non-toxic goitre, unspecified
0.000 0.763 0.237
E61.1 Iron deficiency
0.000 0.764 0.236
E88.2 Lipomatosis, not elsewhere classified
0.000 0.764 0.236
G37.5 Concentric sclerosis [Balo]
0.000 0.765 0.235
G37.4 Subacute necrotising myelitis
0.000 0.765 0.235
G37.2 Central pontine myelinolysis
0.000 0.765 0.235
G37.1 Central demyelination of corpus callosum
0.000 0.765 0.235
G37.0 Diffuse sclerosis
0.000 0.765 0.235
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.765 0.235
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.765 0.235
E72.5 Disorders of glycine metabolism
0.000 0.765 0.235
E72.4 Disorders of ornithine metabolism
0.000 0.765 0.235
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.765 0.235
E72.2 Disorders of urea cycle metabolism
0.000 0.765 0.235
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.765 0.235
E04.8 Other specified non-toxic goitre
0.002 0.765 0.233
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.767 0.233
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.768 0.232
E11.4 With neurological complications
0.000 0.769 0.231
E11.7 With multiple complications
0.000 0.769 0.230
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.771 0.229
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.771 0.229
E70.2 Disorders of tyrosine metabolism
0.000 0.771 0.229
E70.1 Other hyperphenylalaninaemias
0.000 0.771 0.229
E70.0 Classical phenylketonuria
0.000 0.771 0.229
G36.9 Acute disseminated demyelination, unspecified
0.000 0.773 0.227
G36.8 Other specified acute disseminated demyelination
0.000 0.773 0.227
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.773 0.227
G36.0 Neuromyelitis optica [Devic]
0.000 0.773 0.227
E24.8 Other Cushing's syndrome
0.001 0.774 0.225
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.774 0.225
E24.3 Ectopic ACTH syndrome
0.001 0.774 0.225
E24.1 Nelson's syndrome
0.001 0.774 0.225
E11.8 With unspecified complications
0.000 0.776 0.224
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.779 0.221
E89.5 Postprocedural testicular hypofunction
0.000 0.780 0.220
E72.0 Disorders of amino-acid transport
0.000 0.782 0.217
N50 Other disorders of male genital organs
0.217 0.783 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.786 0.214
E11.0 With coma
0.000 0.789 0.211
N30.2 Other chronic cystitis
0.210 0.790 0.000
H30-H36 Disorders of choroid and retina
0.000 0.790 0.210
E11.5 With peripheral circulatory complications
0.000 0.794 0.206
H33.2 Serous retinal detachment
0.000 0.796 0.204
N30 Cystitis
0.204 0.796 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.796 0.203

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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