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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77471165
log Bayes Factor = 21.1513
Chromosome 3   position 111,395,880  (GRCh37) Explore rs77471165 on Ensembl!
Variant rs77471165 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
J22 Unspecified acute lower respiratory infection
1.000 0.000 0.000
J20-J22 Other acute lower respiratory infections
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
M47 Spondylosis
0.996 0.004 0.000
C20 Malignant neoplasm of rectum
0.996 0.004 0.000
C79 Secondary malignant neoplasm of other sites
0.996 0.004 0.000
C78.7 Secondary malignant neoplasm of liver
0.995 0.005 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.994 0.006 0.000
M25 Other joint disorders, not elsewhere classified
0.991 0.009 0.000
M47.9 Spondylosis, unspecified
0.987 0.013 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.986 0.014 0.000
M25.5 Pain in joint
0.985 0.015 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.981 0.019 0.000
F41 Other anxiety disorders
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.973 0.027 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.972 0.028 0.000
C60-C63 Malignant neoplasms of male genital organs
0.971 0.029 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
M48 Other spondylopathies
0.963 0.037 0.000
C61 Malignant neoplasm of prostate
0.955 0.045 0.000
C18 Malignant neoplasm of colon
0.955 0.045 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.954 0.046 0.000
M46 Other inflammatory spondylopathies
0.952 0.048 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.952 0.048 0.000
M79.8 Other specified soft tissue disorders
0.951 0.049 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.950 0.050 0.000
F41.2 Mixed anxiety and depressive disorder
0.949 0.051 0.000
M25.56 Pain in joint (Lower leg)
0.942 0.058 0.000
M65-M68 Disorders of synovium and tendon
0.941 0.059 0.000
A30-A49 Other bacterial diseases
0.940 0.060 0.000
Y43 Primarily systemic agents
0.939 0.061 0.000
M48.0 Spinal stenosis
0.937 0.063 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.926 0.074 0.000
H53-H54 Visual disturbances and blindness
0.922 0.078 0.000
Y95 Nosocomial condition
0.922 0.078 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.919 0.081 0.000
M47.8 Other spondylosis
0.918 0.082 0.000
F41.9 Anxiety disorder, unspecified
0.917 0.083 0.000
M48.06 Spinal stenosis (Lumbar region)
0.916 0.084 0.000
Y43.3 Other antineoplastic drugs
0.916 0.084 0.000
H30-H36 Disorders of choroid and retina
0.911 0.089 0.000
C18.7 Sigmoid colon
0.910 0.090 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.908 0.092 0.000
H53 Visual disturbances
0.906 0.094 0.000
M65 Synovitis and tenosynovitis
0.906 0.094 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.906 0.094 0.000
C15 Malignant neoplasm of oesophagus
0.905 0.095 0.000
M31 Other necrotising vasculopathies
0.905 0.095 0.000
H10-H13 Disorders of conjunctiva
0.903 0.097 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.900 0.100 0.000
J90-J94 Other diseases of pleura
0.899 0.101 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.897 0.103 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.893 0.107 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.892 0.108 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.890 0.110 0.000
M24 Other specific joint derangements
0.889 0.111 0.000
S20-S29 Injuries to the thorax
0.889 0.111 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.884 0.116 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.879 0.121 0.000
H53.9 Visual disturbance, unspecified
0.876 0.124 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.876 0.124 0.000
B95-B98 Bacterial, viral and other infectious agents
0.875 0.125 0.000
A49 Bacterial infection of unspecified site
0.875 0.125 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.874 0.126 0.000
T79-T79 Certain early complications of trauma
0.872 0.128 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.872 0.128 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.861 0.139 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.859 0.141 0.000
Chapter VIII Diseases of the ear and mastoid process
0.857 0.143 0.000
H11 Other disorders of conjunctiva
0.856 0.144 0.000
S40-S49 Injuries to the shoulder and upper arm
0.856 0.144 0.000
F03 Unspecified dementia
0.855 0.145 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.855 0.145 0.000
M79.88 Other specified soft tissue disorders (Other)
0.854 0.146 0.000
D80-D89 Certain disorders involving the immune mechanism
0.852 0.148 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.850 0.149 0.000
F30-F39 Mood [affective] disorders
0.850 0.150 0.000
M91-M94 Chondropathies
0.849 0.151 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.847 0.153 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.847 0.153 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.844 0.156 0.000
M72 Fibroblastic disorders
0.842 0.158 0.000
M47.82 Other spondylosis (Cervical region)
0.835 0.165 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.833 0.167 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.831 0.169 0.000
C15.5 Lower third of oesophagus
0.830 0.170 0.000
M25.53 Pain in joint (Forearm)
0.830 0.170 0.000
M79.0 Rheumatism, unspecified
0.825 0.175 0.000
M40-M43 Deforming dorsopathies
0.823 0.177 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.821 0.179 0.000
M25.50 Pain in joint (Multiple sites)
0.814 0.186 0.000
H34 Retinal vascular occlusions
0.813 0.187 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.813 0.187 0.000
S70-S79 Injuries to the hip and thigh
0.812 0.188 0.000
T91 Sequelae of injuries of neck and trunk
0.811 0.189 0.000
A41 Other septicaemia
0.810 0.190 0.000
F01 Vascular dementia
0.809 0.191 0.000
H35 Other retinal disorders
0.808 0.192 0.000
M25.57 Pain in joint (Ankle and foot)
0.808 0.192 0.000
M25.54 Pain in joint (Hand)
0.806 0.194 0.000
W20-W49 Exposure to inanimate mechanical forces
0.806 0.194 0.000
C16 Malignant neoplasm of stomach
0.805 0.195 0.000
F20 Schizophrenia
0.805 0.195 0.000
S32 Fracture of lumbar spine and pelvis
0.804 0.196 0.000
V40-V49 Car occupant injured in transport accident
0.803 0.197 0.000
D60-D64 Aplastic and other anaemias
0.803 0.197 0.000
M31.3 Wegener's granulomatosis
0.802 0.198 0.000
J60-J70 Lung diseases due to external agents
0.800 0.200 0.000
H53.8 Other visual disturbances
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.797 0.202 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.797 0.203 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.797 0.203 0.000
M35 Other systemic involvement of connective tissue
0.797 0.203 0.000
Chapter XIV Diseases of the genitourinary system
0.794 0.206 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.791 0.209 0.000
M25.51 Pain in joint (Shoulder region)
0.790 0.210 0.000
M45 Ankylosing spondylitis
0.790 0.210 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.788 0.212 0.000
J94 Other pleural conditions
0.788 0.212 0.000
J93 Pneumothorax
0.786 0.214 0.000
N10-N16 Renal tubulo-interstitial diseases
0.783 0.217 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.783 0.217 0.000
M76 Enthesopathies of lower limb, excluding foot
0.780 0.220 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.780 0.220 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.779 0.221 0.000
M86-M90 Other osteopathies
0.779 0.221 0.000
M80-M85 Disorders of bone density and structure
0.778 0.222 0.000
S50-S59 Injuries to the elbow and forearm
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.776 0.224 0.000
A49.9 Bacterial infection, unspecified
0.775 0.225 0.000
H11.3 Conjunctival haemorrhage
0.774 0.226 0.000
A80-A89 Viral infections of the central nervous system
0.774 0.226 0.000
Y40 Systemic antibiotics
0.774 0.226 0.000
H43-H45 Disorders of vitreous body and globe
0.772 0.228 0.000
S60-S69 Injuries to the wrist and hand
0.772 0.228 0.000
T00-T07 Injuries involving multiple body regions
0.771 0.228 0.000
C18.3 Hepatic flexure
0.771 0.229 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.771 0.229 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.771 0.229 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.770 0.230 0.000
C18.6 Descending colon
0.770 0.230 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.769 0.231 0.000
M79.6 Pain in limb
0.769 0.231 0.000
Chapter XXI Factors influencing health status and contact with health services
0.769 0.231 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.768 0.232 0.000
M47.89 Other spondylosis (Site unspecified)
0.768 0.232 0.000
M60-M63 Disorders of muscles
0.768 0.232 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.767 0.233 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.767 0.233 0.000
M15-M19 Arthrosis
0.766 0.234 0.000
N99-N99 Other disorders of the genitourinary system
0.765 0.235 0.000
M71 Other bursopathies
0.765 0.235 0.000
X60-X84 Intentional self-harm
0.761 0.239 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.760 0.240 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.759 0.241 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.759 0.241 0.000
M24.1 Other articular cartilage disorders
0.757 0.243 0.000
F45 Somatoform disorders
0.756 0.244 0.000
F02 Dementia in other diseases classified elsewhere
0.756 0.244 0.000
C18.5 Splenic flexure
0.756 0.244 0.000
M48.02 Spinal stenosis (Cervical region)
0.756 0.244 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.755 0.245 0.000
C17 Malignant neoplasm of small intestine
0.754 0.245 0.000
C78.2 Secondary malignant neoplasm of pleura
0.754 0.246 0.000
M46.4 Discitis, unspecified
0.753 0.247 0.000
M79.7 Fibromyalgia
0.753 0.247 0.000
H53.2 Diplopia
0.752 0.248 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.751 0.248 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.750 0.250 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.749 0.251 0.000
M94 Other disorders of cartilage
0.749 0.251 0.000
F00 Dementia in Alzheimer's disease
0.746 0.253 0.000
M31.6 Other giant cell arteritis
0.746 0.254 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.745 0.254 0.000
M79.1 Myalgia
0.745 0.255 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.745 0.255 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.744 0.256 0.000
Chapter XXII Codes for special purposes
0.743 0.257 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.741 0.259 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.740 0.259 0.000
F80-F89 Disorders of psychological development
0.740 0.260 0.000
A49.0 Staphylococcal infection, unspecified
0.739 0.261 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.738 0.262 0.000
F60-F69 Disorders of adult personality and behaviour
0.737 0.263 0.000
J90 Pleural effusion, not elsewhere classified
0.736 0.264 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.735 0.265 0.000
W50-W64 Exposure to animate mechanical forces
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.735 0.265 0.000
B15-B19 Viral hepatitis
0.734 0.265 0.000
Y57 Other and unspecified drugs and medicaments
0.734 0.266 0.000
S20 Superficial injury of thorax
0.733 0.267 0.000
N13 Obstructive and reflux uropathy
0.732 0.268 0.000
M79.2 Neuralgia and neuritis, unspecified
0.732 0.268 0.000
C18.4 Transverse colon
0.732 0.268 0.000
X50-X57 Overexertion, travel and privation
0.732 0.268 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.732 0.268 0.000
M47.86 Other spondylosis (Lumbar region)
0.730 0.270 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.730 0.270 0.000
C79.2 Secondary malignant neoplasm of skin
0.729 0.270 0.000
H34.8 Other retinal vascular occlusions
0.729 0.271 0.000
D86 Sarcoidosis
0.729 0.271 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.728 0.272 0.000
F42 Obsessive-compulsive disorder
0.728 0.272 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.727 0.273 0.000
C21 Malignant neoplasm of anus and anal canal
0.727 0.273 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.726 0.274 0.000
M00-M03 Infectious arthropathies
0.725 0.275 0.000
A40 Streptococcal septicaemia
0.724 0.276 0.000
F20.9 Schizophrenia, unspecified
0.724 0.276 0.000
S27 Injury of other and unspecified intrathoracic organs
0.721 0.279 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.720 0.280 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.720 0.280 0.000
M25.3 Other instability of joint
0.720 0.280 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.720 0.280 0.000
M70.6 Trochanteric bursitis
0.719 0.281 0.000
H65 Nonsuppurative otitis media
0.718 0.282 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.717 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
H53.1 Subjective visual disturbances
0.717 0.283 0.000
J21 Acute bronchiolitis
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
T92 Sequelae of injuries of upper limb
0.716 0.284 0.000
M47.2 Other spondylosis with radiculopathy
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
H11.0 Pterygium
0.716 0.284 0.000
M25.9 Joint disorder, unspecified
0.715 0.285 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.285 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.714 0.286 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.714 0.286 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.714 0.286 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.714 0.286 0.000
C79.6 Secondary malignant neoplasm of ovary
0.714 0.286 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.714 0.286 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.714 0.286 0.000
H35.4 Peripheral retinal degeneration
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.286 0.000
M33 Dermatopolymyositis
0.713 0.286 0.000
M32 Systemic lupus erythematosus
0.713 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.712 0.287 0.000
M47.1 Other spondylosis with myelopathy
0.712 0.288 0.000
M25.0 Haemarthrosis
0.712 0.288 0.000
S32.5 Fracture of pubis
0.712 0.288 0.000
H35.0 Background retinopathy and retinal vascular changes
0.712 0.288 0.000
H90-H95 Other disorders of ear
0.711 0.289 0.000
M25.2 Flail joint
0.711 0.289 0.000
M25.1 Fistula of joint
0.711 0.289 0.000
J93.9 Pneumothorax, unspecified
0.710 0.290 0.000
M25.59 Pain in joint (Site unspecified)
0.709 0.291 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.708 0.292 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.708 0.292 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.708 0.292 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.708 0.292 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.708 0.292 0.000
F48 Other neurotic disorders
0.707 0.293 0.000
F44 Dissociative [conversion] disorders
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
M25.58 Pain in joint (Other)
0.706 0.294 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.705 0.295 0.000
F33 Recurrent depressive disorder
0.705 0.295 0.000
F01.9 Vascular dementia, unspecified
0.705 0.295 0.000
S90-S99 Injuries to the ankle and foot
0.705 0.295 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.704 0.296 0.000
M79.9 Soft tissue disorder, unspecified
0.703 0.296 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.703 0.296 0.000
M79.3 Panniculitis, unspecified
0.703 0.296 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.703 0.297 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.702 0.298 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.701 0.299 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.700 0.299 0.000
M25.4 Effusion of joint
0.700 0.300 0.000
F41.8 Other specified anxiety disorders
0.700 0.300 0.000
F41.3 Other mixed anxiety disorders
0.700 0.300 0.000
M25.7 Osteophyte
0.700 0.300 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.700 0.300 0.000
T93 Sequelae of injuries of lower limb
0.699 0.301 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.698 0.302 0.000
B02 Zoster [herpes zoster]
0.698 0.302 0.000
B99-B99 Other infectious diseases
0.698 0.302 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.698 0.302 0.000
B65-B83 Helminthiases
0.698 0.302 0.000
B50-B64 Protozoal diseases
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.698 0.302 0.000
A75-A79 Rickettsioses
0.698 0.302 0.000
A70-A74 Other diseases caused by chlamydiae
0.698 0.302 0.000
A65-A69 Other spirochaetal diseases
0.698 0.302 0.000
A20-A28 Certain zoonotic bacterial diseases
0.698 0.302 0.000
A15-A19 Tuberculosis
0.698 0.302 0.000
Z74 Problems related to care-provider dependency
0.698 0.302 0.000
F99-F99 Unspecified mental disorder
0.697 0.303 0.000
Y59 Other and unspecified vaccines and biological substances
0.697 0.303 0.000
Y58 Bacterial vaccines
0.697 0.303 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.697 0.303 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
Y48 Anaesthetics and therapeutic gases
0.697 0.303 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.697 0.303 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.697 0.303 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.696 0.304 0.000
C60 Malignant neoplasm of penis
0.696 0.304 0.000
C77.1 Intrathoracic lymph nodes
0.695 0.305 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.695 0.305 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.694 0.306 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.694 0.306 0.000
C64-C68 Malignant neoplasms of urinary tract
0.693 0.307 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.693 0.307 0.000
M48.9 Spondylopathy, unspecified
0.691 0.309 0.000
M48.8 Other specified spondylopathies
0.691 0.309 0.000
M48.4 Fatigue fracture of vertebra
0.691 0.309 0.000
M48.3 Traumatic spondylopathy
0.691 0.309 0.000
M48.2 Kissing spine
0.691 0.309 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.691 0.309 0.000
H31 Other disorders of choroid
0.691 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.690 0.309 0.000
J20 Acute bronchitis
0.689 0.311 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.689 0.311 0.000
C77.0 Lymph nodes of head, face and neck
0.688 0.312 0.000
A46 Erysipelas
0.687 0.313 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.687 0.313 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.687 0.313 0.000
J94.8 Other specified pleural conditions
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.686 0.314 0.000
M18 Arthrosis of first carpometacarpal joint
0.686 0.314 0.000
C18.8 Overlapping lesion of colon
0.685 0.315 0.000
C18.1 Appendix
0.685 0.315 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.684 0.316 0.000
F40 Phobic anxiety disorders
0.684 0.316 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.684 0.316 0.000
F09 Unspecified organic or symptomatic mental disorder
0.684 0.316 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.684 0.316 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.683 0.317 0.000
M46.8 Other specified inflammatory spondylopathies
0.683 0.317 0.000
M46.5 Other infective spondylopathies
0.683 0.317 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.683 0.317 0.000
M46.2 Osteomyelitis of vertebra
0.683 0.317 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.683 0.317 0.000
M46.0 Spinal enthesopathy
0.683 0.317 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.682 0.317 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.682 0.317 0.000
Y98 Lifestyle-related condition
0.682 0.317 0.000
Y97 Environmental-pollution-related condition
0.682 0.317 0.000
Y96 Work-related condition
0.682 0.317 0.000
M77 Other enthesopathies
0.682 0.317 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.682 0.318 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.682 0.318 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.682 0.318 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.682 0.318 0.000
D55-D59 Haemolytic anaemias
0.681 0.319 0.000
H52 Disorders of refraction and accommodation
0.680 0.320 0.000
M21 Other acquired deformities of limbs
0.678 0.322 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.676 0.323 0.000
Y40.0 Penicillins
0.677 0.323 0.000
M43 Other deforming dorsopathies
0.676 0.324 0.000
D70 Agranulocytosis
0.676 0.324 0.000
C78.0 Secondary malignant neoplasm of lung
0.676 0.324 0.000
C15.9 Oesophagus, unspecified
0.676 0.324 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.675 0.325 0.000
S42 Fracture of shoulder and upper arm
0.675 0.325 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.674 0.326 0.000
M66 Spontaneous rupture of synovium and tendon
0.674 0.326 0.000
F32 Depressive episode
0.674 0.326 0.000
A48 Other bacterial diseases, not elsewhere classified
0.674 0.326 0.000
A44 Bartonellosis
0.674 0.326 0.000
A43 Nocardiosis
0.674 0.326 0.000
A42 Actinomycosis
0.674 0.326 0.000
A39 Meningococcal infection
0.674 0.326 0.000
A37 Whooping cough
0.674 0.326 0.000
A36 Diphtheria
0.674 0.326 0.000
A32 Listeriosis
0.674 0.326 0.000
A31 Infection due to other mycobacteria
0.674 0.326 0.000
A30 Leprosy [Hansen's disease]
0.674 0.326 0.000
A38 Scarlet fever
0.674 0.326 0.000
A35 Other tetanus
0.674 0.326 0.000
A34 Obstetrical tetanus
0.674 0.326 0.000
A33 Tetanus neonatorum
0.674 0.326 0.000
J69 Pneumonitis due to solids and liquids
0.674 0.326 0.000
Y43.9 Primarily systemic agent, unspecified
0.673 0.327 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.673 0.327 0.000
Y43.6 Enzymes, not elsewhere classified
0.673 0.327 0.000
Y43.5 Acidifying and alkalising agents
0.673 0.327 0.000
Y43.4 Immunosuppressive agents
0.673 0.327 0.000
Y43.2 Antineoplastic natural products
0.673 0.327 0.000
Y43.1 Antineoplastic antimetabolites
0.673 0.327 0.000
Y43.0 Antiallergic and antiemetic drugs
0.673 0.327 0.000
D69 Purpura and other haemorrhagic conditions
0.673 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.673 0.327 0.000
Z51 Other medical care
0.673 0.327 0.000
C25 Malignant neoplasm of pancreas
0.673 0.327 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.672 0.328 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.672 0.328 0.000
M48.04 Spinal stenosis (Thoracic region)
0.672 0.328 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.672 0.328 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.672 0.328 0.000
Y54.4 Loop [high-ceiling] diuretics
0.672 0.328 0.000
S70 Superficial injury of hip and thigh
0.672 0.328 0.000
M79.69 Pain in limb (Site unspecified)
0.672 0.328 0.000
M79.5 Residual foreign body in soft tissue
0.672 0.328 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.671 0.329 0.000
M25.52 Pain in joint (Upper arm)
0.670 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.330 0.000
Y45.1 Salicylates
0.669 0.331 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.669 0.331 0.000
H44 Disorders of globe
0.669 0.331 0.000
A41.9 Septicaemia, unspecified
0.668 0.332 0.000
N00-N08 Glomerular diseases
0.668 0.332 0.000
F20.0 Paranoid schizophrenia
0.668 0.332 0.000
M50-M54 Other dorsopathies
0.668 0.332 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.668 0.332 0.000
Y45.2 Propionic acid derivatives
0.667 0.333 0.000
C16.0 Cardia
0.667 0.333 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.666 0.333 0.000
M34 Systemic sclerosis
0.666 0.334 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.666 0.334 0.000
A49.8 Other bacterial infections of unspecified site
0.666 0.334 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.666 0.334 0.000
N17-N19 Renal failure
0.665 0.335 0.000
D62 Acute posthaemorrhagic anaemia
0.665 0.335 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.665 0.335 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.664 0.335 0.000
M25.8 Other specified joint disorders
0.664 0.335 0.000
M24.0 Loose body in joint
0.663 0.337 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.662 0.338 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.662 0.338 0.000
M05-M14 Inflammatory polyarthropathies
0.661 0.339 0.000
Y52 Agents primarily affecting the cardiovascular system
0.660 0.340 0.000
F30 Manic episode
0.659 0.341 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.658 0.342 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.658 0.342 0.000
M47.84 Other spondylosis (Thoracic region)
0.658 0.342 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.658 0.342 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.658 0.342 0.000
C77.8 Lymph nodes of multiple regions
0.658 0.342 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.658 0.342 0.000
C77.2 Intra-abdominal lymph nodes
0.657 0.343 0.000
H33 Retinal detachments and breaks
0.656 0.344 0.000
S40 Superficial injury of shoulder and upper arm
0.656 0.344 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.656 0.344 0.000
F43 Reaction to severe stress, and adjustment disorders
0.656 0.344 0.000
Z51.5 Palliative care
0.656 0.344 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.655 0.345 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.655 0.345 0.000
M24.2 Disorder of ligament
0.655 0.345 0.000
T79.6 Traumatic ischaemia of muscle
0.655 0.345 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.654 0.346 0.000
M24.5 Contracture of joint
0.654 0.346 0.000
C16.5 Lesser curvature of stomach, unspecified
0.654 0.346 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.653 0.347 0.000
H30 Chorioretinal inflammation
0.653 0.347 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.653 0.347 0.000
J91 Pleural effusion in conditions classified elsewhere
0.652 0.347 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.653 0.347 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.652 0.348 0.000
F23 Acute and transient psychotic disorders
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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