TreeWAS – Variant ID: rs7748494

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
J45 Asthma	0.000	0.000	1.000
J40-J47 Chronic lower respiratory diseases	0.000	0.000	1.000
# Top node	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.001	0.999
Chapter XI Diseases of the digestive system	0.000	0.001	0.999
K90 Intestinal malabsorption	0.000	0.001	0.999
Chapter X Diseases of the respiratory system	0.000	0.001	0.999
M06.9 Rheumatoid arthritis, unspecified	0.000	0.001	0.999
K90-K93 Other diseases of the digestive system	0.000	0.001	0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.002	0.998
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.003	0.997
Chapter II Neoplasms	0.000	0.005	0.995
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.007	0.993
C44 Other malignant neoplasms of skin	0.000	0.007	0.993
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.009	0.991
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.010	0.990
C44.3 Skin of other and unspecified parts of face	0.000	0.011	0.989
J44 Other chronic obstructive pulmonary disease	0.000	0.014	0.986
K29 Gastritis and duodenitis	0.000	0.018	0.982
K29.8 Duodenitis	0.000	0.022	0.978
D60-D64 Aplastic and other anaemias	0.000	0.025	0.975
M06 Other rheumatoid arthritis	0.004	0.031	0.966
D64 Other anaemias	0.000	0.033	0.967
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.036	0.964
D64.9 Anaemia, unspecified	0.000	0.039	0.961
C44.7 Skin of lower limb, including hip	0.000	0.042	0.958
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.057	0.943
M05-M14 Inflammatory polyarthropathies	0.018	0.066	0.916
E05.9 Thyrotoxicosis, unspecified	0.000	0.073	0.927
K20 Oesophagitis	0.000	0.074	0.926
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.028	0.076	0.896
J00-J06 Acute upper respiratory infections	0.000	0.085	0.915
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.090	0.910
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.093	0.907
K22 Other diseases of oesophagus	0.000	0.095	0.905
J20-J22 Other acute lower respiratory infections	0.000	0.095	0.905
K70-K77 Diseases of liver	0.000	0.105	0.895
M80-M85 Disorders of bone density and structure	0.022	0.112	0.866
J46 Status asthmaticus	0.000	0.113	0.887
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.117	0.883
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.119	0.881
K29.4 Chronic atrophic gastritis	0.000	0.122	0.878
D00-D09 In situ neoplasms	0.000	0.124	0.876
K22.2 Oesophageal obstruction	0.000	0.125	0.875
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.125	0.875
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.126	0.874
E10-E14 Diabetes mellitus	0.000	0.129	0.871
M81 Osteoporosis without pathological fracture	0.011	0.130	0.859
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.134	0.866
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.140	0.860
M81.9 Osteoporosis, unspecified	0.003	0.141	0.856
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.143	0.857
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.146	0.854
J22 Unspecified acute lower respiratory infection	0.000	0.154	0.846
D06 Carcinoma in situ of cervix uteri	0.000	0.155	0.845
K70 Alcoholic liver disease	0.000	0.157	0.843
E11 Non-insulin-dependent diabetes mellitus	0.000	0.157	0.843
C44.0 Skin of lip	0.000	0.158	0.842
C51-C58 Malignant neoplasms of female genital organs	0.000	0.161	0.839
E11.3 With ophthalmic complications	0.000	0.167	0.833
J02 Acute pharyngitis	0.000	0.172	0.828
M06.0 Seronegative rheumatoid arthritis	0.002	0.172	0.826
E06 Thyroiditis	0.000	0.173	0.827
D06.9 Cervix, unspecified	0.000	0.178	0.822
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.179	0.821
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.184	0.816
E50-E64 Other nutritional deficiencies	0.000	0.186	0.814
D69 Purpura and other haemorrhagic conditions	0.000	0.190	0.810
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.190	0.810
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.201	0.799
K22.1 Ulcer of oesophagus	0.000	0.203	0.797
K70.9 Alcoholic liver disease, unspecified	0.000	0.209	0.791
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.209	0.791
C73 Malignant neoplasm of thyroid gland	0.000	0.212	0.788
D45 Polycythaemia vera	0.000	0.215	0.785
K92 Other diseases of digestive system	0.000	0.219	0.781
K29.5 Chronic gastritis, unspecified	0.000	0.219	0.781
K29.1 Other acute gastritis	0.000	0.220	0.780
M05 Seropositive rheumatoid arthritis	0.011	0.222	0.767
L40-L45 Papulosquamous disorders	0.000	0.224	0.776
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.224	0.776
D80-D89 Certain disorders involving the immune mechanism	0.000	0.226	0.774
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.226	0.774
D69.6 Thrombocytopenia, unspecified	0.000	0.229	0.771
J02.9 Acute pharyngitis, unspecified	0.000	0.234	0.766
K35-K38 Diseases of appendix	0.000	0.234	0.766
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.238	0.762
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.241	0.759
K27 Peptic ulcer, site unspecified	0.000	0.242	0.758
L57.0 Actinic keratosis	0.000	0.242	0.758
D62 Acute posthaemorrhagic anaemia	0.000	0.250	0.750
E20-E35 Disorders of other endocrine glands	0.000	0.251	0.749
C53 Malignant neoplasm of cervix uteri	0.000	0.259	0.741
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.264	0.736
C44.4 Skin of scalp and neck	0.000	0.273	0.727
Chapter XXII Codes for special purposes	0.000	0.273	0.727
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.274	0.725
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.276	0.724
C54 Malignant neoplasm of corpus uteri	0.000	0.277	0.723
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.277	0.723
L40 Psoriasis	0.000	0.278	0.722
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.279	0.721
K22.9 Disease of oesophagus, unspecified	0.000	0.280	0.720
K26 Duodenal ulcer	0.000	0.280	0.720
E11.4 With neurological complications	0.000	0.281	0.719
K92.0 Haematemesis	0.000	0.281	0.719
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
J45.8 Mixed asthma	0.000	0.283	0.717
J45.1 Nonallergic asthma	0.000	0.283	0.717
J41 Simple and mucopurulent chronic bronchitis	0.000	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.283	0.716
K90.8 Other intestinal malabsorption	0.000	0.284	0.716
K90.3 Pancreatic steatorrhoea	0.000	0.284	0.716
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.284	0.716
K90.1 Tropical sprue	0.000	0.284	0.716
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.284	0.716
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.284	0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.284	0.716
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.284	0.716
Chapter I Certain infectious and parasitic diseases	0.000	0.284	0.716
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.286	0.714
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.286	0.714
C44.8 Overlapping lesion of skin	0.000	0.288	0.712
E07 Other disorders of thyroid	0.000	0.290	0.710
K28 Gastrojejunal ulcer	0.000	0.290	0.710
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.290	0.710
D55-D59 Haemolytic anaemias	0.000	0.293	0.706
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.294	0.706
K29.9 Gastroduodenitis, unspecified	0.000	0.295	0.704
K29.2 Alcoholic gastritis	0.000	0.295	0.704
J45.0 Predominantly allergic asthma	0.000	0.296	0.704
E06.3 Autoimmune thyroiditis	0.000	0.297	0.703
K72 Hepatic failure, not elsewhere classified	0.000	0.299	0.701
E55 Vitamin D deficiency	0.000	0.300	0.700
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.301	0.699
J01 Acute sinusitis	0.000	0.304	0.695
M06.8 Other specified rheumatoid arthritis	0.003	0.305	0.692
M06.4 Inflammatory polyarthropathy	0.003	0.305	0.692
M06.3 Rheumatoid nodule	0.003	0.305	0.692
M06.2 Rheumatoid bursitis	0.003	0.305	0.692
M06.1 Adult-onset Still's disease	0.003	0.305	0.692
C81 Hodgkin's disease	0.000	0.305	0.695
J03 Acute tonsillitis	0.000	0.306	0.694
D64.8 Other specified anaemias	0.000	0.307	0.693
D64.4 Congenital dyserythropoietic anaemia	0.000	0.307	0.693
D64.3 Other sideroblastic anaemias	0.000	0.307	0.693
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.307	0.693
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.307	0.693
D64.0 Hereditary sideroblastic anaemia	0.000	0.307	0.693
E05.8 Other thyrotoxicosis	0.000	0.308	0.691
E05.5 Thyroid crisis or storm	0.000	0.308	0.691
E05.4 Thyrotoxicosis factitia	0.000	0.308	0.691
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.308	0.691
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.308	0.691
K29.3 Chronic superficial gastritis	0.000	0.312	0.688
M81.98 Osteoporosis, unspecified (Other)	0.002	0.313	0.685
J95-J99 Other diseases of the respiratory system	0.000	0.317	0.682
B35-B49 Mycoses	0.000	0.318	0.682
C60-C63 Malignant neoplasms of male genital organs	0.000	0.320	0.680
C44.5 Skin of trunk	0.000	0.321	0.679
M07 Psoriatic and enteropathic arthropathies	0.012	0.321	0.667
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.323	0.677
M91-M94 Chondropathies	0.019	0.325	0.657
K31 Other diseases of stomach and duodenum	0.000	0.325	0.675
C44.1 Skin of eyelid, including canthus	0.000	0.326	0.674
K22.8 Other specified diseases of oesophagus	0.000	0.326	0.674
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.329	0.671
C53.9 Cervix uteri, unspecified	0.000	0.329	0.671
M14 Arthropathies in other diseases classified elsewhere	0.013	0.330	0.656
M12 Other specific arthropathies	0.013	0.330	0.656
M09 Juvenile arthritis in diseases classified elsewhere	0.013	0.330	0.656
M08 Juvenile arthritis	0.013	0.330	0.656
J04 Acute laryngitis and tracheitis	0.000	0.332	0.668
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.333	0.667
C09 Malignant neoplasm of tonsil	0.000	0.334	0.666
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.334	0.661
E03.8 Other specified hypothyroidism	0.000	0.334	0.665
L40.9 Psoriasis, unspecified	0.000	0.336	0.664
C44.2 Skin of ear and external auricular canal	0.000	0.340	0.660
B37 Candidiasis	0.000	0.340	0.660
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.341	0.659
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.342	0.658
D47.2 Monoclonal gammopathy	0.000	0.343	0.657
C92 Myeloid leukaemia	0.000	0.343	0.657
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.344	0.656
D75 Other diseases of blood and blood-forming organs	0.000	0.344	0.656
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.346	0.654
K70.3 Alcoholic cirrhosis of liver	0.000	0.347	0.653
K92.1 Melaena	0.000	0.347	0.653
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.347	0.653
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.350	0.650
C95 Leukaemia of unspecified cell type	0.000	0.350	0.650
C94 Other leukaemias of specified cell type	0.000	0.350	0.650
C93 Monocytic leukaemia	0.000	0.350	0.650
C86 Other specified types of T/NK-cell lymphoma	0.000	0.350	0.650
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.350	0.650
K22.3 Perforation of oesophagus	0.000	0.351	0.649
K22.4 Dyskinesia of oesophagus	0.000	0.351	0.649
J21 Acute bronchiolitis	0.000	0.351	0.649
J00 Acute nasopharyngitis [common cold]	0.000	0.352	0.648
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.353	0.646
K90.9 Intestinal malabsorption, unspecified	0.000	0.355	0.645
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.355	0.645
K77 Liver disorders in diseases classified elsewhere	0.000	0.358	0.642
K73 Chronic hepatitis, not elsewhere classified	0.000	0.358	0.642
K71 Toxic liver disease	0.000	0.358	0.642
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.358	0.642
D86 Sarcoidosis	0.000	0.359	0.641
C54.1 Endometrium	0.000	0.360	0.640
K65-K67 Diseases of peritoneum	0.000	0.360	0.640
K70.4 Alcoholic hepatic failure	0.000	0.361	0.639
C64-C68 Malignant neoplasms of urinary tract	0.000	0.362	0.638
M83 Adult osteomalacia	0.016	0.363	0.621
M82 Osteoporosis in diseases classified elsewhere	0.016	0.363	0.621
E04 Other non-toxic goitre	0.000	0.364	0.635
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.366	0.633
D67 Hereditary factor IX deficiency	0.000	0.367	0.633
D66 Hereditary factor VIII deficiency	0.000	0.367	0.633
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.367	0.633
M00-M03 Infectious arthropathies	0.021	0.368	0.611
M11 Other crystal arthropathies	0.013	0.369	0.618
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.371	0.629
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.371	0.628
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.371	0.628
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.371	0.628
D05 Carcinoma in situ of breast	0.000	0.372	0.628
K76 Other diseases of liver	0.000	0.373	0.627
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.373	0.627
C74 Malignant neoplasm of adrenal gland	0.000	0.373	0.627
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.373	0.627
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.373	0.627
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.373	0.627
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.373	0.627
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.373	0.627
B37.8 Candidiasis of other sites	0.000	0.375	0.625
D46 Myelodysplastic syndromes	0.000	0.375	0.625
M60-M63 Disorders of muscles	0.021	0.375	0.603
C91 Lymphoid leukaemia	0.000	0.375	0.624
E12 Malnutrition-related diabetes mellitus	0.000	0.376	0.624
M81.8 Other osteoporosis	0.008	0.376	0.616
M81.6 Localised osteoporosis [Lequesne]	0.008	0.376	0.616
M81.5 Idiopathic osteoporosis	0.008	0.376	0.616
M81.3 Postsurgical malabsorption osteoporosis	0.008	0.376	0.616
M81.2 Osteoporosis of disuse	0.008	0.376	0.616
M81.1 Postoophorectomy osteoporosis	0.008	0.376	0.616
M81.0 Postmenopausal osteoporosis	0.008	0.376	0.616
E11.5 With peripheral circulatory complications	0.000	0.380	0.620
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.381	0.619
E55.9 Vitamin D deficiency, unspecified	0.000	0.382	0.618
D68 Other coagulation defects	0.000	0.383	0.617
L10-L14 Bullous disorders	0.000	0.383	0.617
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.384	0.616
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.384	0.613
M81.96 Osteoporosis, unspecified (Lower leg)	0.003	0.384	0.613
M81.94 Osteoporosis, unspecified (Hand)	0.003	0.384	0.613
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.384	0.613
M81.92 Osteoporosis, unspecified (Upper arm)	0.003	0.384	0.613
M81.91 Osteoporosis, unspecified (Shoulder region)	0.003	0.384	0.613
J20 Acute bronchitis	0.000	0.385	0.614
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.386	0.614
C88 Malignant immunoproliferative diseases	0.000	0.389	0.611
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.389	0.611
E53 Deficiency of other B group vitamins	0.000	0.390	0.610
E11.6 With other specified complications	0.000	0.391	0.609
C51 Malignant neoplasm of vulva	0.000	0.393	0.607
D06.7 Other parts of cervix	0.000	0.394	0.606
D06.1 Exocervix	0.000	0.394	0.606
D06.0 Endocervix	0.000	0.394	0.606
K37 Unspecified appendicitis	0.000	0.395	0.605
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.396	0.604
K70.0 Alcoholic fatty liver	0.000	0.396	0.604
E11.8 With unspecified complications	0.000	0.396	0.604
E11.7 With multiple complications	0.000	0.396	0.604
K50-K52 Noninfective enteritis and colitis	0.019	0.396	0.585
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.398	0.601
C58 Malignant neoplasm of placenta	0.000	0.398	0.601
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.398	0.601
C52 Malignant neoplasm of vagina	0.000	0.398	0.601
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.401	0.599
E29 Testicular dysfunction	0.000	0.402	0.598
E21.0 Primary hyperparathyroidism	0.000	0.403	0.597
M80 Osteoporosis with pathological fracture	0.016	0.403	0.581
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.405	0.594
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.406	0.594
J02.0 Streptococcal pharyngitis	0.000	0.406	0.594
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.406	0.594
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.406	0.592
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.406	0.592
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.406	0.592
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.406	0.592
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.406	0.592
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.406	0.592
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.406	0.592
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.406	0.592
E06.9 Thyroiditis, unspecified	0.000	0.407	0.593
E06.5 Other chronic thyroiditis	0.000	0.407	0.593
E06.4 Drug-induced thyroiditis	0.000	0.407	0.593
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.407	0.593
E06.1 Subacute thyroiditis	0.000	0.407	0.593
E06.0 Acute thyroiditis	0.000	0.407	0.593
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.407	0.593
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.408	0.592
M81.4 Drug-induced osteoporosis	0.008	0.408	0.584
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.409	0.591
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.410	0.590
M10 Gout	0.011	0.410	0.579
K29.0 Acute haemorrhagic gastritis	0.000	0.411	0.589
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.411	0.588
C82.6 Cutaneous follicle centre lymphoma	0.000	0.411	0.588
C82.5 Diffuse follicle centre lymphoma	0.000	0.411	0.588
C82.4 Follicular lymphoma grade IIIb	0.000	0.411	0.588
C82.3 Follicular lymphoma grade IIIa	0.000	0.411	0.588
C82.2 Large cell, follicular	0.000	0.411	0.588
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.411	0.588
C82.0 Small cleaved cell, follicular	0.000	0.411	0.588
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.414	0.586
K70.1 Alcoholic hepatitis	0.000	0.414	0.585
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.416	0.584
E63 Other nutritional deficiencies	0.000	0.416	0.584
E56 Other vitamin deficiencies	0.000	0.416	0.584
E51 Thiamine deficiency	0.000	0.416	0.584
E50 Vitamin A deficiency	0.000	0.416	0.584
E60 Dietary zinc deficiency	0.000	0.416	0.584
E59 Dietary selenium deficiency	0.000	0.416	0.584
E58 Dietary calcium deficiency	0.000	0.416	0.584
E54 Ascorbic acid deficiency	0.000	0.416	0.584
E52 Niacin deficiency [pellagra]	0.000	0.416	0.584
D75.1 Secondary polycythaemia	0.000	0.416	0.584
K75 Other inflammatory liver diseases	0.000	0.417	0.583
M40-M43 Deforming dorsopathies	0.019	0.417	0.564
E40-E46 Malnutrition	0.000	0.417	0.583
D69.9 Haemorrhagic condition, unspecified	0.000	0.419	0.581
D69.8 Other specified haemorrhagic conditions	0.000	0.419	0.581
D69.4 Other primary thrombocytopenia	0.000	0.419	0.581
D69.2 Other nonthrombocytopenic purpura	0.000	0.419	0.581
D69.1 Qualitative platelet defects	0.000	0.419	0.581
D69.0 Allergic purpura	0.000	0.419	0.581
M85 Other disorders of bone density and structure	0.016	0.419	0.564
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.419	0.581
L58 Radiodermatitis	0.000	0.419	0.581
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.419	0.581
L55 Sunburn	0.000	0.419	0.581
C85.1 B-cell lymphoma, unspecified	0.000	0.420	0.580
E11.0 With coma	0.000	0.420	0.579
D09 Carcinoma in situ of other and unspecified sites	0.000	0.422	0.578
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.021	0.422	0.557
L40.5 Arthropathic psoriasis	0.000	0.423	0.577
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.423	0.577
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.423	0.577
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.424	0.574
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.426	0.571
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.427	0.573
C13 Malignant neoplasm of hypopharynx	0.000	0.427	0.573
C11 Malignant neoplasm of nasopharynx	0.000	0.427	0.573
C10 Malignant neoplasm of oropharynx	0.000	0.427	0.573
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.427	0.573
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.427	0.573
C05 Malignant neoplasm of palate	0.000	0.427	0.573
C04 Malignant neoplasm of floor of mouth	0.000	0.427	0.573
C03 Malignant neoplasm of gum	0.000	0.427	0.573
C00 Malignant neoplasm of lip	0.000	0.427	0.573
C12 Malignant neoplasm of pyriform sinus	0.000	0.427	0.573
C07 Malignant neoplasm of parotid gland	0.000	0.427	0.573
J60-J70 Lung diseases due to external agents	0.000	0.427	0.573
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.428	0.570
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.429	0.571
C09.9 Tonsil, unspecified	0.000	0.429	0.571
L08 Other local infections of skin and subcutaneous tissue	0.000	0.430	0.570
L82 Seborrhoeic keratosis	0.000	0.431	0.569
E13 Other specified diabetes mellitus	0.000	0.434	0.565
K72.9 Hepatic failure, unspecified	0.000	0.438	0.562
K92.8 Other specified diseases of digestive system	0.000	0.440	0.560
K22.5 Diverticulum of oesophagus, acquired	0.000	0.442	0.558
M05.8 Other seropositive rheumatoid arthritis	0.008	0.442	0.550
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.008	0.442	0.550
M05.2 Rheumatoid vasculitis	0.008	0.442	0.550
M05.1 Rheumatoid lung disease	0.008	0.442	0.550
M05.0 Felty's syndrome	0.008	0.442	0.550
K22.0 Achalasia of cardia	0.000	0.442	0.557
L44 Other papulosquamous disorders	0.000	0.443	0.557
L41 Parapsoriasis	0.000	0.443	0.557
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.443	0.557
L42 Pityriasis rosea	0.000	0.443	0.557
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.444	0.556
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.444	0.556
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.444	0.556
D47.4 Osteomyelofibrosis	0.000	0.444	0.556
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.444	0.556
K35 Acute appendicitis	0.000	0.444	0.556
D68.9 Coagulation defect, unspecified	0.000	0.444	0.556
E23 Hypofunction and other disorders of pituitary gland	0.000	0.445	0.555
D84 Other immunodeficiencies	0.000	0.445	0.555
D83 Common variable immunodeficiency	0.000	0.445	0.555
D82 Immunodeficiency associated with other major defects	0.000	0.445	0.555
D81 Combined immunodeficiencies	0.000	0.445	0.555
D80 Immunodeficiency with predominantly antibody defects	0.000	0.445	0.555
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.445	0.555
L57.5 Actinic granuloma	0.000	0.445	0.555
L57.4 Cutis laxa senilis	0.000	0.445	0.555
L57.3 Poikiloderma of Civatte	0.000	0.445	0.555
L57.2 Cutis rhomboidalis nuchae	0.000	0.445	0.555
L57.1 Actinic reticuloid	0.000	0.445	0.555
E14 Unspecified diabetes mellitus	0.000	0.446	0.553
D47.1 Chronic myeloproliferative disease	0.000	0.447	0.553
K31.7 Polyp of stomach and duodenum	0.000	0.447	0.553
B37.0 Candidal stomatitis	0.000	0.447	0.553
D72 Other disorders of white blood cells	0.000	0.450	0.550
C50-C50 Malignant neoplasm of breast	0.000	0.451	0.549
K36 Other appendicitis	0.000	0.451	0.549
D61 Other aplastic anaemias	0.000	0.452	0.548
J47 Bronchiectasis	0.000	0.453	0.547
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.453	0.547
D74 Methaemoglobinaemia	0.000	0.453	0.547
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.453	0.547
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.453	0.547
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.454	0.546
K26.4 Chronic or unspecified with haemorrhage	0.000	0.454	0.546
B90-B94 Sequelae of infectious and parasitic diseases	0.000	0.454	0.546
D50-D53 Nutritional anaemias	0.000	0.454	0.545
B07 Viral warts	0.000	0.455	0.545
K27.7 Chronic without haemorrhage or perforation	0.000	0.456	0.543
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.456	0.543
K27.5 Chronic or unspecified with perforation	0.000	0.456	0.543
K27.4 Chronic or unspecified with haemorrhage	0.000	0.456	0.543
K27.3 Acute without haemorrhage or perforation	0.000	0.456	0.543
K27.2 Acute with both haemorrhage and perforation	0.000	0.456	0.543
K27.1 Acute with perforation	0.000	0.456	0.543
K27.0 Acute with haemorrhage	0.000	0.456	0.543
C81.9 Hodgkin's disease, unspecified	0.000	0.457	0.543
K76.9 Liver disease, unspecified	0.000	0.458	0.542
E07.9 Disorder of thyroid, unspecified	0.000	0.458	0.542
K74 Fibrosis and cirrhosis of liver	0.000	0.461	0.539
J01.9 Acute sinusitis, unspecified	0.000	0.462	0.538
J90-J94 Other diseases of pleura	0.000	0.462	0.538
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.463	0.537
E32 Diseases of thymus	0.000	0.463	0.537
E31 Polyglandular dysfunction	0.000	0.463	0.537
E30 Disorders of puberty, not elsewhere classified	0.000	0.463	0.537
E26 Hyperaldosteronism	0.000	0.463	0.537
E25 Adrenogenital disorders	0.000	0.463	0.537
E20 Hypoparathyroidism	0.000	0.463	0.537
D04 Carcinoma in situ of skin	0.000	0.463	0.537
C67 Malignant neoplasm of bladder	0.000	0.464	0.536
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.464	0.536
J03.9 Acute tonsillitis, unspecified	0.000	0.464	0.536
L43 Lichen planus	0.000	0.464	0.536
E11.1 With ketoacidosis	0.000	0.466	0.534
D86.0 Sarcoidosis of lung	0.000	0.466	0.534
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.466	0.534
K38 Other diseases of appendix	0.000	0.468	0.532
K51 Ulcerative colitis	0.008	0.468	0.524
C53.8 Overlapping lesion of cervix uteri	0.000	0.468	0.531
C53.1 Exocervix	0.000	0.468	0.531
C53.0 Endocervix	0.000	0.468	0.531
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.470	0.530
L50-L54 Urticaria and erythema	0.000	0.471	0.529
D63.0 Anaemia in neoplastic disease	0.000	0.471	0.529
C90.0 Multiple myeloma	0.000	0.472	0.528
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.472	0.528
C85.0 Lymphosarcoma	0.000	0.472	0.528
C01 Malignant neoplasm of base of tongue	0.000	0.473	0.527
L40.0 Psoriasis vulgaris	0.000	0.475	0.525
C92.0 Acute myeloid leukaemia	0.000	0.476	0.524
D70 Agranulocytosis	0.000	0.476	0.524
J95.8 Other postprocedural respiratory disorders	0.000	0.476	0.523
E11.2 With renal complications	0.000	0.477	0.523
C44.6 Skin of upper limb, including shoulder	0.000	0.479	0.521
E27 Other disorders of adrenal gland	0.000	0.481	0.519
C54.9 Corpus uteri, unspecified	0.000	0.482	0.518
C54.8 Overlapping lesion of corpus uteri	0.000	0.482	0.518
C54.3 Fundus uteri	0.000	0.482	0.518
C54.2 Myometrium	0.000	0.482	0.518
C54.0 Isthmus uteri	0.000	0.482	0.518
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.482	0.518
E21.3 Hyperparathyroidism, unspecified	0.000	0.482	0.518
L40.8 Other psoriasis	0.000	0.482	0.517
L40.4 Guttate psoriasis	0.000	0.482	0.517
L40.3 Pustulosis palmaris et plantaris	0.000	0.482	0.517
L40.2 Acrodermatitis continua	0.000	0.482	0.517
L40.1 Generalised pustular psoriasis	0.000	0.482	0.517
B20-B24 Human immunodeficiency virus [HIV] disease	0.000	0.483	0.517
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.484	0.516
K26.2 Acute with both haemorrhage and perforation	0.000	0.484	0.516
K26.1 Acute with perforation	0.000	0.484	0.516
K26.0 Acute with haemorrhage	0.000	0.484	0.516
B25-B34 Other viral diseases	0.000	0.484	0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations