TreeWAS – Variant ID: rs7749823

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
E27 Other disorders of adrenal gland	0.998	0.002	0.000
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
E10.3 With ophthalmic complications	0.997	0.003	0.000
H25-H28 Disorders of lens	0.994	0.006	0.000
H26 Other cataract	0.990	0.010	0.000
H26.9 Cataract, unspecified	0.988	0.012	0.000
H30-H36 Disorders of choroid and retina	0.981	0.019	0.000
D80-D89 Certain disorders involving the immune mechanism	0.977	0.023	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.976	0.024	0.000
M20-M25 Other joint disorders	0.973	0.027	0.000
N40 Hyperplasia of prostate	0.000	0.028	0.972
D86 Sarcoidosis	0.966	0.034	0.000
M23 Internal derangement of knee	0.964	0.036	0.000
H36 Retinal disorders in diseases classified elsewhere	0.960	0.040	0.000
H53-H54 Visual disturbances and blindness	0.956	0.044	0.000
H54 Blindness and low vision	0.945	0.055	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.945	0.055	0.000
H36.0 Diabetic retinopathy	0.945	0.055	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.942	0.058	0.000
H43-H45 Disorders of vitreous body and globe	0.940	0.060	0.000
D86.9 Sarcoidosis, unspecified	0.939	0.061	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.935	0.065	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.929	0.071	0.000
H34 Retinal vascular occlusions	0.928	0.072	0.000
R31 Unspecified haematuria	0.000	0.074	0.926
D69 Purpura and other haemorrhagic conditions	0.925	0.075	0.000
M05-M14 Inflammatory polyarthropathies	0.922	0.078	0.000
Chapter II Neoplasms	0.921	0.079	0.000
H54.4 Blindness, one eye	0.919	0.081	0.000
K90 Intestinal malabsorption	0.917	0.082	0.001
E10.2 With renal complications	0.916	0.084	0.000
E14 Unspecified diabetes mellitus	0.915	0.085	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.908	0.092	0.000
C43 Malignant melanoma of skin	0.907	0.093	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.905	0.095	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.095	0.905
M60-M63 Disorders of muscles	0.903	0.097	0.000
D61 Other aplastic anaemias	0.902	0.098	0.000
E23 Hypofunction and other disorders of pituitary gland	0.897	0.103	0.000
H43 Disorders of vitreous body	0.890	0.110	0.000
M34 Systemic sclerosis	0.890	0.110	0.000
M22 Disorders of patella	0.887	0.113	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.886	0.114	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.882	0.118	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.880	0.120	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.880	0.120	0.000
D55-D59 Haemolytic anaemias	0.879	0.121	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.877	0.123	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.876	0.124	0.000
C43.5 Malignant melanoma of trunk	0.875	0.125	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.873	0.127	0.000
K90.9 Intestinal malabsorption, unspecified	0.872	0.128	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.869	0.131	0.000
H43.1 Vitreous haemorrhage	0.867	0.133	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.865	0.135	0.000
H54.7 Unspecified visual loss	0.865	0.135	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.857	0.143	0.000
M10 Gout	0.856	0.144	0.000
C91 Lymphoid leukaemia	0.845	0.155	0.000
M23.4 Loose body in knee	0.843	0.157	0.000
M62 Other disorders of muscle	0.839	0.161	0.000
C85.1 B-cell lymphoma, unspecified	0.837	0.163	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.834	0.166	0.000
H34.2 Other retinal artery occlusions	0.833	0.167	0.000
E10.5 With peripheral circulatory complications	0.832	0.168	0.000
E11 Non-insulin-dependent diabetes mellitus	0.830	0.170	0.000
M23.8 Other internal derangements of knee	0.829	0.171	0.000
M65-M68 Disorders of synovium and tendon	0.828	0.172	0.000
H34.8 Other retinal vascular occlusions	0.827	0.173	0.000
E14.3 With ophthalmic complications	0.826	0.174	0.000
M24 Other specific joint derangements	0.825	0.175	0.000
E10.1 With ketoacidosis	0.824	0.176	0.000
M23.3 Other meniscus derangements	0.823	0.177	0.000
C81 Hodgkin's disease	0.821	0.178	0.000
M11 Other crystal arthropathies	0.821	0.179	0.000
C83.3 Large cell (diffuse)	0.819	0.181	0.000
D69.4 Other primary thrombocytopenia	0.819	0.181	0.000
D61.9 Aplastic anaemia, unspecified	0.814	0.186	0.000
D69.9 Haemorrhagic condition, unspecified	0.810	0.190	0.000
M00-M03 Infectious arthropathies	0.808	0.192	0.000
C43.9 Malignant melanoma of skin, unspecified	0.808	0.192	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.808	0.192	0.000
C43.4 Malignant melanoma of scalp and neck	0.807	0.193	0.000
C82.2 Large cell, follicular	0.804	0.196	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.801	0.199	0.000
M21 Other acquired deformities of limbs	0.799	0.201	0.000
H31 Other disorders of choroid	0.797	0.203	0.000
D86.8 Sarcoidosis of other and combined sites	0.796	0.203	0.000
E31 Polyglandular dysfunction	0.796	0.204	0.000
N40-N51 Diseases of male genital organs	0.000	0.205	0.795
E14.1 With ketoacidosis	0.794	0.206	0.000
E20 Hypoparathyroidism	0.794	0.206	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.793	0.207	0.000
M34.9 Systemic sclerosis, unspecified	0.792	0.208	0.000
H26.4 After-cataract	0.791	0.209	0.000
M22.8 Other disorders of patella	0.786	0.214	0.000
N42 Other disorders of prostate	0.000	0.214	0.786
M31 Other necrotising vasculopathies	0.786	0.214	0.000
E29 Testicular dysfunction	0.785	0.215	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.781	0.219	0.000
M10.0 Idiopathic gout	0.780	0.220	0.000
H47.2 Optic atrophy	0.779	0.221	0.000
M22.3 Other derangements of patella	0.775	0.225	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.775	0.225	0.001
D59 Acquired haemolytic anaemia	0.775	0.225	0.000
E11.3 With ophthalmic complications	0.775	0.225	0.000
D86.3 Sarcoidosis of skin	0.774	0.225	0.000
D86.1 Sarcoidosis of lymph nodes	0.772	0.228	0.000
E16.1 Other hypoglycaemia	0.771	0.229	0.000
E22 Hyperfunction of pituitary gland	0.770	0.230	0.000
E10.6 With other specified complications	0.769	0.231	0.000
H46 Optic neuritis	0.769	0.231	0.000
H27 Other disorders of lens	0.768	0.232	0.000
H16 Keratitis	0.768	0.232	0.000
E13 Other specified diabetes mellitus	0.766	0.234	0.000
E05.8 Other thyrotoxicosis	0.762	0.238	0.000
D64.8 Other specified anaemias	0.762	0.238	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.761	0.239	0.000
N42.8 Other specified disorders of prostate	0.000	0.243	0.757
D69.6 Thrombocytopenia, unspecified	0.756	0.244	0.000
M33 Dermatopolymyositis	0.755	0.245	0.000
M14 Arthropathies in other diseases classified elsewhere	0.754	0.246	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.752	0.248	0.000
N32 Other disorders of bladder	0.000	0.250	0.750
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.747	0.253	0.000
E10.8 With unspecified complications	0.747	0.253	0.000
N32.0 Bladder-neck obstruction	0.000	0.254	0.746
C91.1 Chronic lymphocytic leukaemia	0.746	0.254	0.000
E23.0 Hypopituitarism	0.745	0.255	0.000
E10.0 With coma	0.744	0.256	0.000
M23.5 Chronic instability of knee	0.744	0.256	0.000
E27.2 Addisonian crisis	0.743	0.257	0.000
H30 Chorioretinal inflammation	0.743	0.257	0.000
M21.0 Valgus deformity, not elsewhere classified	0.741	0.259	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.740	0.260	0.000
H18 Other disorders of cornea	0.740	0.260	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.738	0.262	0.000
M11.2 Other chondrocalcinosis	0.738	0.262	0.000
H26.1 Traumatic cataract	0.737	0.263	0.000
N30-N39 Other diseases of urinary system	0.000	0.263	0.737
E23.2 Diabetes insipidus	0.736	0.263	0.000
M23.9 Internal derangement of knee, unspecified	0.736	0.264	0.000
H54.6 Unqualified visual loss, one eye	0.735	0.265	0.000
M23.49 Loose body in knee-Unspec lig/men	0.731	0.269	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.730	0.270	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.730	0.270	0.000
H47.3 Other disorders of optic disk	0.728	0.272	0.000
H43.9 Disorder of vitreous body, unspecified	0.728	0.272	0.000
Chapter XIV Diseases of the genitourinary system	0.000	0.272	0.728
M62.8 Other specified disorders of muscle	0.727	0.273	0.000
C91.0 Acute lymphoblastic leukaemia	0.726	0.274	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.726	0.274	0.000
M35 Other systemic involvement of connective tissue	0.726	0.274	0.000
C95 Leukaemia of unspecified cell type	0.724	0.276	0.000
H26.2 Complicated cataract	0.723	0.277	0.000
E23.7 Disorder of pituitary gland, unspecified	0.722	0.278	0.000
D84 Other immunodeficiencies	0.721	0.278	0.000
M34.1 CR(E)ST syndrome	0.721	0.279	0.000
N20-N23 Urolithiasis	0.000	0.279	0.721
D86.0 Sarcoidosis of lung	0.720	0.280	0.000
C07 Malignant neoplasm of parotid gland	0.719	0.281	0.000
M23.1 Discoid meniscus (congenital)	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
M32 Systemic lupus erythematosus	0.716	0.283	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
H44 Disorders of globe	0.716	0.284	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.716	0.284	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
M23.0 Cystic meniscus	0.715	0.285	0.000
E50-E64 Other nutritional deficiencies	0.714	0.286	0.000
N20 Calculus of kidney and ureter	0.000	0.286	0.714
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.712	0.288	0.000
N32.8 Other specified disorders of bladder	0.000	0.288	0.712
E14.6 With other specified complications	0.710	0.290	0.000
C83.7 Burkitt's tumour	0.710	0.290	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.710	0.290	0.000
H26.3 Drug-induced cataract	0.709	0.290	0.000
Chapter X Diseases of the respiratory system	0.709	0.291	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.708	0.292	0.000
E24 Cushing's syndrome	0.707	0.293	0.000
M10.9 Gout, unspecified	0.707	0.293	0.000
M62.6 Muscle strain	0.706	0.294	0.000
C02.1 Border of tongue	0.706	0.294	0.000
N20.0 Calculus of kidney	0.000	0.296	0.704
H32 Chorioretinal disorders in diseases classified elsewhere	0.703	0.297	0.000
D82 Immunodeficiency associated with other major defects	0.700	0.300	0.000
D81 Combined immunodeficiencies	0.700	0.300	0.000
D61.0 Constitutional aplastic anaemia	0.699	0.301	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.301	0.699
M60 Myositis	0.698	0.302	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.698	0.302	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.697	0.303	0.000
M35.0 Sicca syndrome [Sjogren]	0.694	0.306	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.693	0.307	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.693	0.307	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.693	0.307	0.000
Q43 Other congenital malformations of intestine	0.692	0.308	0.000
J95-J99 Other diseases of the respiratory system	0.692	0.308	0.000
D83 Common variable immunodeficiency	0.692	0.308	0.000
M07 Psoriatic and enteropathic arthropathies	0.692	0.308	0.000
D69.0 Allergic purpura	0.690	0.309	0.000
C02.9 Tongue, unspecified	0.690	0.310	0.000
M00 Pyogenic arthritis	0.689	0.311	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.688	0.312	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.688	0.312	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.688	0.312	0.000
C82.0 Small cleaved cell, follicular	0.688	0.312	0.000
E14.5 With peripheral circulatory complications	0.687	0.313	0.000
Q39 Congenital malformations of oesophagus	0.687	0.313	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.687	0.313	0.000
C81.9 Hodgkin's disease, unspecified	0.687	0.313	0.000
H16.9 Keratitis, unspecified	0.687	0.313	0.000
H47.1 Papilloedema, unspecified	0.687	0.313	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.685	0.315	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.685	0.315	0.000
C03 Malignant neoplasm of gum	0.684	0.316	0.000
H27.0 Aphakia	0.684	0.316	0.000
C81.2 Mixed cellularity	0.684	0.316	0.000
N32.3 Diverticulum of bladder	0.000	0.319	0.681
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.319	0.681
N20.1 Calculus of ureter	0.000	0.319	0.681
H54.2 Low vision, both eyes	0.681	0.319	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.680	0.320	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.321	0.679
E14.2 Withrenal complications	0.678	0.322	0.000
J98 Other respiratory disorders	0.678	0.322	0.000
C09 Malignant neoplasm of tonsil	0.678	0.322	0.000
H54.3 Unqualified visual loss, both eyes	0.678	0.322	0.000
H54.1 Blindness, one eye, low vision, other eye	0.678	0.322	0.000
E34 Other endocrine disorders	0.677	0.323	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.676	0.324	0.000
H54.9 Unspecified visual impairment (binocular)	0.675	0.325	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.675	0.325	0.000
C91.9 Lymphoid leukaemia, unspecified	0.674	0.325	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.674	0.326	0.000
J90-J94 Other diseases of pleura	0.674	0.326	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.674	0.326	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.327	0.673
Q50-Q56 Congenital malformations of genital organs	0.673	0.327	0.000
D58 Other hereditary haemolytic anaemias	0.672	0.328	0.000
C83.0 Small cell (diffuse)	0.670	0.329	0.000
D67 Hereditary factor IX deficiency	0.670	0.330	0.000
M15-M19 Arthrosis	0.670	0.330	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.669	0.331	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.669	0.331	0.000
H43.8 Other disorders of vitreous body	0.667	0.333	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.666	0.334	0.000
C94 Other leukaemias of specified cell type	0.666	0.334	0.000
C93 Monocytic leukaemia	0.666	0.334	0.000
C86 Other specified types of T/NK-cell lymphoma	0.666	0.334	0.000
H54.5 Low vision, one eye	0.666	0.334	0.000
H34.9 Retinal vascular occlusion, unspecified	0.665	0.335	0.000
H34.0 Transient retinal artery occlusion	0.665	0.335	0.000
N34 Urethritis and urethral syndrome	0.000	0.335	0.665
E11.6 With other specified complications	0.664	0.336	0.000
D69.8 Other specified haemorrhagic conditions	0.663	0.337	0.000
D69.2 Other nonthrombocytopenic purpura	0.663	0.337	0.000
D69.1 Qualitative platelet defects	0.663	0.337	0.000
M34.8 Other forms of systemic sclerosis	0.661	0.339	0.000
M12 Other specific arthropathies	0.661	0.339	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.661	0.339	0.000
M08 Juvenile arthritis	0.661	0.339	0.000
M23.40 Loose body in knee-Mult sites	0.661	0.339	0.000
M24.1 Other articular cartilage disorders	0.660	0.340	0.000
J92 Pleural plaque	0.659	0.341	0.000
K90.8 Other intestinal malabsorption	0.658	0.341	0.001
K90.3 Pancreatic steatorrhoea	0.658	0.341	0.001
K90.2 Blind loop syndrome, not elsewhere classified	0.658	0.341	0.001
K90.1 Tropical sprue	0.658	0.341	0.001
M23.80 Other internal derangements of knee (Multiple sites)	0.658	0.342	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.657	0.343	0.000
M67 Other disorders of synovium and tendon	0.656	0.344	0.000
E14.7 With multiple complications	0.656	0.344	0.000
E14.0 With coma	0.656	0.344	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.656	0.344	0.000
H34.1 Central retinal artery occlusion	0.655	0.345	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.655	0.345	0.000
H31.8 Other specified disorders of choroid	0.655	0.345	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.654	0.346	0.000
E14.8 With unspecified complications	0.654	0.346	0.000
E40-E46 Malnutrition	0.653	0.347	0.000
E31.0 Autoimmune polyglandular failure	0.651	0.349	0.000
C43.8 Overlapping malignant melanoma of skin	0.650	0.350	0.000
C43.0 Malignant melanoma of lip	0.650	0.350	0.000
M66 Spontaneous rupture of synovium and tendon	0.649	0.351	0.000
C85.0 Lymphosarcoma	0.649	0.351	0.000
D59.1 Other autoimmune haemolytic anaemias	0.648	0.352	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.648	0.352	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.648	0.352	0.000
M61 Calcification and ossification of muscle	0.648	0.352	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.647	0.353	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.353	0.647
E20.9 Hypoparathyroidism, unspecified	0.647	0.353	0.000
D61.8 Other specified aplastic anaemias	0.647	0.353	0.000
D61.3 Idiopathic aplastic anaemia	0.647	0.353	0.000
D61.2 Aplastic anaemia due to other external agents	0.647	0.353	0.000
D61.1 Drug-induced aplastic anaemia	0.647	0.353	0.000
C13 Malignant neoplasm of hypopharynx	0.646	0.354	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.646	0.354	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.646	0.354	0.000
C01 Malignant neoplasm of base of tongue	0.646	0.354	0.000
M22.2 Patellofemoral disorders	0.645	0.355	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.643	0.357	0.000
E23.1 Drug-induced hypopituitarism	0.643	0.357	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.643	0.357	0.000
Q44.5 Other congenital malformations of bile ducts	0.642	0.358	0.000
E03.8 Other specified hypothyroidism	0.641	0.358	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.641	0.359	0.000
C05 Malignant neoplasm of palate	0.641	0.359	0.000
M65 Synovitis and tenosynovitis	0.641	0.359	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.640	0.359	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.640	0.360	0.000
C10 Malignant neoplasm of oropharynx	0.640	0.360	0.000
N32.1 Vesicointestinal fistula	0.000	0.361	0.639
H43.0 Vitreous prolapse	0.638	0.362	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.638	0.362	0.000
M34.0 Progressive systemic sclerosis	0.638	0.362	0.000
H54.0 Blindness, both eyes	0.638	0.362	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.637	0.363	0.000
J93 Pneumothorax	0.636	0.364	0.000
M31.6 Other giant cell arteritis	0.636	0.364	0.000
M22.1 Recurrent subluxation of patella	0.636	0.364	0.000
M22.9 Disorder of patella, unspecified	0.636	0.364	0.000
Q35-Q37 Cleft lip and cleft palate	0.635	0.364	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.635	0.364	0.000
H25 Senile cataract	0.634	0.366	0.000
M14.6 Neuropathic arthropathy	0.633	0.367	0.000
C82.6 Cutaneous follicle centre lymphoma	0.633	0.367	0.000
C82.5 Diffuse follicle centre lymphoma	0.633	0.367	0.000
C82.4 Follicular lymphoma grade IIIb	0.633	0.367	0.000
C82.3 Follicular lymphoma grade IIIa	0.633	0.367	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.632	0.368	0.000
E29.1 Testicular hypofunction	0.632	0.368	0.000
H15 Disorders of sclera	0.631	0.369	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.631	0.369	0.000
H47.7 Disorder of visual pathways, unspecified	0.631	0.369	0.000
H47.6 Disorders of visual cortex	0.631	0.369	0.000
H47.5 Disorders of other visual pathways	0.631	0.369	0.000
H47.4 Disorders of optic chiasm	0.631	0.369	0.000
C88 Malignant immunoproliferative diseases	0.631	0.369	0.000
C11 Malignant neoplasm of nasopharynx	0.631	0.369	0.000
D57 Sickle-cell disorders	0.630	0.370	0.000
D56 Thalassaemia	0.630	0.370	0.000
D55 Anaemia due to enzyme disorders	0.630	0.370	0.000
E06 Thyroiditis	0.630	0.370	0.000
Q40 Other congenital malformations of upper alimentary tract	0.630	0.370	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.628	0.371	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.627	0.373	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.626	0.374	0.000
C00 Malignant neoplasm of lip	0.626	0.374	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.625	0.375	0.000
C91.5 Adult T-cell leukaemia	0.624	0.375	0.000
J92.0 Pleural plaque with presence of asbestos	0.623	0.377	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.623	0.377	0.000
Q45 Other congenital malformations of digestive system	0.623	0.377	0.000
Q44.6 Cystic disease of liver	0.623	0.377	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.623	0.377	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.622	0.377	0.000
H43.2 Crystalline deposits in vitreous body	0.621	0.379	0.000
C83.6 Undifferentiated (diffuse)	0.620	0.379	0.000
C83.5 Lymphoblastic (diffuse)	0.620	0.379	0.000
C83.4 Immunoblastic (diffuse)	0.620	0.379	0.000
C83.2 Mixed small and large cell (diffuse)	0.620	0.379	0.000
M11.9 Crystal arthropathy, unspecified	0.620	0.380	0.000
H31.0 Chorioretinal scars	0.620	0.380	0.000
M21.1 Varus deformity, not elsewhere classified	0.618	0.382	0.000
E23.6 Other disorders of pituitary gland	0.618	0.382	0.000
D62 Acute posthaemorrhagic anaemia	0.617	0.382	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.617	0.383	0.000
E11.0 With coma	0.617	0.383	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.617	0.383	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.617	0.383	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.384	0.616
M18 Arthrosis of first carpometacarpal joint	0.616	0.384	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.614	0.385	0.000
C81.0 Lymphocytic predominance	0.614	0.386	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.614	0.386	0.000
M10.4 Other secondary gout	0.614	0.386	0.000
M10.3 Gout due to impairment of renal function	0.614	0.386	0.000
M10.2 Drug-induced gout	0.614	0.386	0.000
M10.1 Lead-induced gout	0.614	0.386	0.000
D66 Hereditary factor VIII deficiency	0.614	0.386	0.000
D00-D09 In situ neoplasms	0.613	0.387	0.000
D80 Immunodeficiency with predominantly antibody defects	0.612	0.388	0.000
E10.4 With neurological complications	0.611	0.388	0.000
H25.0 Senile incipient cataract	0.611	0.389	0.000
M23.43 Loose body in knee-Med lig/oth men	0.610	0.390	0.000
M21.7 Unequal limb length (acquired)	0.607	0.393	0.000
C83.1 Small cleaved cell (diffuse)	0.607	0.393	0.000
M22.0 Recurrent dislocation of patella	0.606	0.394	0.000
H17 Corneal scars and opacities	0.606	0.394	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.606	0.394	0.000
C91.7 Other lymphoid leukaemia	0.606	0.394	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.606	0.394	0.000
C91.3 Prolymphocytic leukaemia	0.606	0.394	0.000
C91.2 Subacute lymphocytic leukaemia	0.606	0.394	0.000
C02.2 Ventral surface of tongue	0.605	0.395	0.000
M23.47 Loose body in knee-Capsular lig	0.604	0.395	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.604	0.395	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.604	0.395	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.604	0.395	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.604	0.395	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.604	0.396	0.000
Q00-Q07 Congenital malformations of the nervous system	0.604	0.396	0.000
N34.2 Other urethritis	0.000	0.396	0.604
M13 Other arthritis	0.603	0.397	0.000
H26.0 Infantile, juvenile and presenile cataract	0.603	0.397	0.000
M00.9 Pyogenic arthritis, unspecified	0.603	0.397	0.000
E22.1 Hyperprolactinaemia	0.602	0.398	0.000
M24.2 Disorder of ligament	0.602	0.398	0.000
M62.9 Disorder of muscle, unspecified	0.601	0.399	0.000
M62.4 Contracture of muscle	0.601	0.399	0.000
M62.3 Immobility syndrome (paraplegic)	0.601	0.399	0.000
M62.2 Ischaemic infarction of muscle	0.601	0.399	0.000
M62.0 Diastasis of muscle	0.601	0.399	0.000
M24.5 Contracture of joint	0.601	0.399	0.000
M24.7 Protrusio acetabuli	0.600	0.400	0.000
H18.5 Hereditary corneal dystrophies	0.600	0.400	0.000
E27.8 Other specified disorders of adrenal gland	0.599	0.401	0.000
H18.0 Corneal pigmentations and deposits	0.599	0.401	0.000
E13.9 Without complications	0.599	0.401	0.000
E11.5 With peripheral circulatory complications	0.599	0.401	0.000
J92.9 Pleural plaque without asbestos	0.598	0.402	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.598	0.402	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.598	0.402	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.598	0.402	0.000
M23.46 Loose body in knee-O/unsp lat men	0.597	0.403	0.000
Q60-Q64 Congenital malformations of the urinary system	0.597	0.403	0.000
M33.1 Other dermatomyositis	0.597	0.403	0.000
E11.7 With multiple complications	0.595	0.405	0.000
N23 Unspecified renal colic	0.000	0.405	0.595
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.595	0.405	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.595	0.405	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.594	0.406	0.000
M62.66 Muscle strain (Lower leg)	0.593	0.406	0.000
E11.4 With neurological complications	0.593	0.407	0.000
M24.9 Joint derangement, unspecified	0.591	0.409	0.000
M23.37 Other meniscus derangements-Capsular lig	0.590	0.410	0.000
E24.2 Drug-induced Cushing's syndrome	0.590	0.410	0.000
Q43.8 Other specified congenital malformations of intestine	0.589	0.410	0.000
H16.3 Interstitial and deep keratitis	0.589	0.411	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.589	0.411	0.000
Chapter XXII Codes for special purposes	0.589	0.411	0.000
C81.7 Other Hodgkin's disease	0.589	0.411	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.589	0.411	0.000
C81.3 Lymphocytic depletion	0.589	0.411	0.000
M11.8 Other specified crystal arthropathies	0.589	0.411	0.000
M11.1 Familial chondrocalcinosis	0.589	0.411	0.000
M11.0 Hydroxyapatite deposition disease	0.589	0.411	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations