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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77528658
log Bayes Factor = 12.135
Chromosome 9   position 104,204,920  (GRCh37) Explore rs77528658 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
I69 Sequelae of cerebrovascular disease
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.998 0.002 0.000
S01 Open wound of head
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
S01.8 Open wound of other parts of head
0.990 0.010 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.963 0.037 0.000
Chapter XI Diseases of the digestive system
0.959 0.041 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.955 0.045 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.953 0.047 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.952 0.048 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.951 0.049 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.951 0.049 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.949 0.051 0.000
K70-K77 Diseases of liver
0.946 0.054 0.000
S00 Superficial injury of head
0.940 0.060 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.938 0.062 0.000
K90-K93 Other diseases of the digestive system
0.932 0.068 0.000
I44 Atrioventricular and left bundle-branch block
0.930 0.070 0.000
S50-S59 Injuries to the elbow and forearm
0.930 0.070 0.000
I31 Other diseases of pericardium
0.922 0.078 0.000
K92 Other diseases of digestive system
0.922 0.078 0.000
I49 Other cardiac arrhythmias
0.920 0.080 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.920 0.080 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.919 0.081 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.916 0.084 0.000
S90-S99 Injuries to the ankle and foot
0.911 0.089 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.906 0.094 0.000
I69.3 Sequelae of cerebral infarction
0.905 0.095 0.000
K92.0 Haematemesis
0.905 0.095 0.000
Y95 Nosocomial condition
0.904 0.096 0.000
K70 Alcoholic liver disease
0.896 0.104 0.000
T66-T78 Other and unspecified effects of external causes
0.893 0.107 0.000
I46 Cardiac arrest
0.889 0.111 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.883 0.117 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.876 0.124 0.000
I47 Paroxysmal tachycardia
0.875 0.125 0.000
I42 Cardiomyopathy
0.870 0.130 0.000
K92.1 Melaena
0.867 0.133 0.000
G81 Hemiplegia
0.863 0.137 0.000
S00.1 Contusion of eyelid and periocular area
0.863 0.137 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.862 0.138 0.000
S20-S29 Injuries to the thorax
0.862 0.138 0.000
X60-X84 Intentional self-harm
0.861 0.139 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.860 0.140 0.000
S01.5 Open wound of lip and oral cavity
0.859 0.141 0.000
T39.1 4-Aminophenol derivatives
0.858 0.142 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.856 0.144 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.855 0.145 0.000
I05-I09 Chronic rheumatic heart diseases
0.852 0.148 0.000
K76 Other diseases of liver
0.851 0.149 0.000
S01.1 Open wound of eyelid and periocular area
0.850 0.150 0.000
K70.9 Alcoholic liver disease, unspecified
0.849 0.151 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.844 0.156 0.000
S06 Intracranial injury
0.843 0.157 0.000
T86 Failure and rejection of transplanted organs and tissues
0.840 0.160 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.839 0.161 0.000
G82 Paraplegia and tetraplegia
0.838 0.162 0.000
I31.3 Pericardial effusion (noninflammatory)
0.837 0.163 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.836 0.164 0.000
I46.0 Cardiac arrest with successful resuscitation
0.830 0.170 0.000
K35-K38 Diseases of appendix
0.827 0.173 0.000
G30-G32 Other degenerative diseases of the nervous system
0.825 0.175 0.000
W00-W19 Falls
0.817 0.183 0.000
S01.0 Open wound of scalp
0.817 0.183 0.000
Y57 Other and unspecified drugs and medicaments
0.814 0.186 0.000
S00.8 Superficial injury of other parts of head
0.813 0.187 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.812 0.188 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.810 0.190 0.000
R42 Dizziness and giddiness
0.809 0.191 0.000
I49.9 Cardiac arrhythmia, unspecified
0.808 0.192 0.000
I35 Nonrheumatic aortic valve disorders
0.807 0.193 0.000
S05 Injury of eye and orbit
0.807 0.193 0.000
S92 Fracture of foot, except ankle
0.805 0.195 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.805 0.195 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.805 0.195 0.000
G20-G26 Extrapyramidal and movement disorders
0.804 0.196 0.000
I44.7 Left bundle-branch block, unspecified
0.804 0.196 0.000
K14 Diseases of tongue
0.803 0.196 0.000
I67 Other cerebrovascular diseases
0.803 0.197 0.000
Chapter XXII Codes for special purposes
0.803 0.197 0.000
I49.1 Atrial premature depolarisation
0.802 0.198 0.000
S02 Fracture of skull and facial bones
0.801 0.199 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.801 0.199 0.000
T91 Sequelae of injuries of neck and trunk
0.801 0.199 0.000
G81.9 Hemiplegia, unspecified
0.797 0.203 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
S01.4 Open wound of cheek and temporomandibular area
0.793 0.207 0.000
I49.3 Ventricular premature depolarisation
0.793 0.207 0.000
Y43 Primarily systemic agents
0.793 0.207 0.000
K10 Other diseases of jaws
0.792 0.208 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.792 0.208 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.792 0.208 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.790 0.210 0.000
I44.2 Atrioventricular block, complete
0.787 0.213 0.000
I51 Complications and ill-defined descriptions of heart disease
0.787 0.213 0.000
G40-G47 Episodic and paroxysmal disorders
0.786 0.214 0.000
T78 Adverse effects, not elsewhere classified
0.785 0.215 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.784 0.216 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.782 0.218 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.778 0.222 0.000
G51 Facial nerve disorders
0.778 0.222 0.000
G70-G73 Diseases of myoneural junction and muscle
0.776 0.224 0.000
Y00-Y09 Assault
0.776 0.224 0.000
S27 Injury of other and unspecified intrathoracic organs
0.776 0.224 0.000
I42.0 Dilated cardiomyopathy
0.774 0.226 0.000
I33 Acute and subacute endocarditis
0.771 0.229 0.000
S50 Superficial injury of forearm
0.769 0.231 0.000
K14.8 Other diseases of tongue
0.769 0.231 0.000
S09 Other and unspecified injuries of head
0.767 0.233 0.000
T51 Toxic effect of alcohol
0.766 0.234 0.000
S70-S79 Injuries to the hip and thigh
0.765 0.235 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.764 0.236 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.764 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.763 0.237 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.763 0.237 0.000
Chapter V Mental and behavioural disorders
0.761 0.239 0.000
S00.7 Multiple superficial injuries of head
0.761 0.239 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.759 0.241 0.000
S56 Injury of muscle and tendon at forearm level
0.756 0.244 0.000
I31.9 Disease of pericardium, unspecified
0.755 0.245 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.754 0.246 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.754 0.246 0.000
S54 Injury of nerves at forearm level
0.753 0.247 0.000
V10-V19 Pedal cyclist injured in transport accident
0.753 0.247 0.000
X20-X29 Contact with venomous animals and plants
0.752 0.248 0.000
I08 Multiple valve diseases
0.751 0.249 0.000
I44.3 Other and unspecified atrioventricular block
0.750 0.250 0.000
K72 Hepatic failure, not elsewhere classified
0.750 0.250 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.750 0.250 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.748 0.252 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.747 0.253 0.000
V20-V29 Motorcycle rider injured in transport accident
0.745 0.255 0.000
I49.0 Ventricular fibrillation and flutter
0.744 0.256 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.743 0.257 0.000
T93 Sequelae of injuries of lower limb
0.743 0.257 0.000
G80 Infantile cerebral palsy
0.742 0.257 0.000
Y52 Agents primarily affecting the cardiovascular system
0.740 0.260 0.000
R45 Symptoms and signs involving emotional state
0.740 0.260 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.739 0.261 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.739 0.261 0.000
T90 Sequelae of injuries of head
0.738 0.262 0.000
S92.0 Fracture of calcaneus
0.737 0.263 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.735 0.265 0.000
X78 Intentional self-harm by sharp object
0.734 0.266 0.000
K07 Dentofacial anomalies [including malocclusion]
0.733 0.267 0.000
T85.2 Mechanical complication of intraocular lens
0.733 0.267 0.000
I47.2 Ventricular tachycardia
0.733 0.267 0.000
G50 Disorders of trigeminal nerve
0.732 0.268 0.000
T40.2 Other opioids
0.731 0.269 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.730 0.269 0.000
K70.1 Alcoholic hepatitis
0.730 0.270 0.000
T78.3 Angioneurotic oedema
0.729 0.271 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.729 0.271 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.729 0.271 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.728 0.272 0.000
K74 Fibrosis and cirrhosis of liver
0.727 0.273 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.727 0.273 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.727 0.273 0.000
I44.6 Other and unspecified fascicular block
0.723 0.277 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.722 0.278 0.000
K76.6 Portal hypertension
0.722 0.278 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.721 0.279 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.721 0.279 0.000
I38 Endocarditis, valve unspecified
0.720 0.280 0.000
S80-S89 Injuries to the knee and lower leg
0.720 0.280 0.000
V40-V49 Car occupant injured in transport accident
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.717 0.283 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.716 0.284 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.716 0.284 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.716 0.284 0.000
I62 Other nontraumatic intracranial haemorrhage
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
S01.7 Multiple open wounds of head
0.715 0.285 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.714 0.286 0.000
S51 Open wound of forearm
0.713 0.287 0.000
I44.1 Atrioventricular block, second degree
0.713 0.287 0.000
R87 Abnormal findings in specimens from female genital organs
0.713 0.287 0.000
T68 Hypothermia
0.713 0.287 0.000
D70 Agranulocytosis
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.710 0.289 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.708 0.292 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.708 0.292 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.707 0.293 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.707 0.293 0.000
G30 Alzheimer's disease
0.707 0.293 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.705 0.294 0.000
I47.1 Supraventricular tachycardia
0.705 0.295 0.000
I61 Intracerebral haemorrhage
0.705 0.295 0.000
S52 Fracture of forearm
0.705 0.295 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.704 0.296 0.000
I50 Heart failure
0.704 0.296 0.000
K92.8 Other specified diseases of digestive system
0.702 0.298 0.000
K75 Other inflammatory liver diseases
0.702 0.298 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.702 0.298 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.702 0.298 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.702 0.298 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.702 0.298 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
Q50-Q56 Congenital malformations of genital organs
0.701 0.299 0.000
G82.2 Paraplegia, unspecified
0.700 0.300 0.000
S32 Fracture of lumbar spine and pelvis
0.700 0.300 0.000
G83 Other paralytic syndromes
0.698 0.302 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.697 0.303 0.000
I47.0 Reentry ventricular arrhythmia
0.696 0.304 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.695 0.305 0.000
I51.9 Heart disease, unspecified
0.693 0.307 0.000
K10.8 Other specified diseases of jaws
0.693 0.307 0.000
G82.5 Tetraplegia, unspecified
0.693 0.307 0.000
Y44 Agents primarily affecting blood constituents
0.691 0.308 0.000
Y57.9 Drug or medicament, unspecified
0.691 0.309 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.691 0.309 0.000
I20-I25 Ischaemic heart diseases
0.690 0.310 0.000
I49.8 Other specified cardiac arrhythmias
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.690 0.310 0.000
Q80-Q89 Other congenital malformations
0.689 0.311 0.000
S92.00 Fracture of calcaneus (closed)
0.689 0.311 0.000
I35.0 Aortic (valve) stenosis
0.688 0.312 0.000
K76.9 Liver disease, unspecified
0.687 0.313 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.683 0.317 0.000
T98 Sequelae of other and unspecified effects of external causes
0.683 0.317 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.682 0.317 0.000
G52 Disorders of other cranial nerves
0.682 0.317 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.682 0.318 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.682 0.318 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.682 0.318 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.682 0.318 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.681 0.318 0.000
Y98 Lifestyle-related condition
0.681 0.318 0.000
Y97 Environmental-pollution-related condition
0.681 0.318 0.000
Y96 Work-related condition
0.681 0.318 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.682 0.318 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.680 0.320 0.000
K10.2 Inflammatory conditions of jaws
0.680 0.320 0.000
I60 Subarachnoid haemorrhage
0.679 0.321 0.000
R09.1 Pleurisy
0.679 0.321 0.000
I67.8 Other specified cerebrovascular diseases
0.678 0.322 0.000
K77 Liver disorders in diseases classified elsewhere
0.678 0.322 0.000
K73 Chronic hepatitis, not elsewhere classified
0.678 0.322 0.000
K71 Toxic liver disease
0.678 0.322 0.000
S99 Other and unspecified injuries of ankle and foot
0.677 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
S02.0 Fracture of vault of skull
0.676 0.324 0.000
W06 Fall involving bed
0.676 0.324 0.000
S00.5 Superficial injury of lip and oral cavity
0.674 0.326 0.000
S00.4 Superficial injury of ear
0.674 0.326 0.000
S00.3 Superficial injury of nose
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.326 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.672 0.328 0.000
K35 Acute appendicitis
0.671 0.329 0.000
S90 Superficial injury of ankle and foot
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.670 0.330 0.000
T86.0 Bone-marrow transplant rejection
0.670 0.330 0.000
S06.5 Traumatic subdural haemorrhage
0.670 0.330 0.000
D60-D64 Aplastic and other anaemias
0.669 0.331 0.000
I42.2 Other hypertrophic cardiomyopathy
0.669 0.331 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.668 0.331 0.000
R45.1 Restlessness and agitation
0.668 0.332 0.000
I44.5 Left posterior fascicular block
0.667 0.333 0.000
I44.4 Left anterior fascicular block
0.667 0.333 0.000
S59 Other and unspecified injuries of forearm
0.667 0.333 0.000
S58 Traumatic amputation of forearm
0.667 0.333 0.000
S57 Crushing injury of forearm
0.667 0.333 0.000
S55 Injury of blood vessels at forearm level
0.667 0.333 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.667 0.333 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.665 0.335 0.000
T51.0 Ethanol
0.665 0.335 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.664 0.336 0.000
S06.4 Epidural haemorrhage
0.664 0.336 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.662 0.338 0.000
I31.8 Other specified diseases of pericardium
0.661 0.339 0.000
I31.2 Haemopericardium, not elsewhere classified
0.661 0.339 0.000
I31.1 Chronic constrictive pericarditis
0.661 0.339 0.000
I31.0 Chronic adhesive pericarditis
0.661 0.339 0.000
T59 Toxic effect of other gases, fumes and vapours
0.660 0.339 0.000
I49.2 Junctional premature depolarisation
0.660 0.340 0.000
T95 Sequelae of burns, corrosions and frostbite
0.659 0.341 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.659 0.341 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
I08.8 Other multiple valve diseases
0.659 0.341 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.659 0.341 0.000
S06.3 Focal brain injury
0.656 0.344 0.000
T79-T79 Certain early complications of trauma
0.656 0.344 0.000
R85.5 Abnormal microbiological findings
0.656 0.344 0.000
R43 Disturbances of smell and taste
0.655 0.345 0.000
W19 Unspecified fall
0.655 0.345 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.655 0.345 0.000
K92.9 Disease of digestive system, unspecified
0.655 0.345 0.000
K38 Other diseases of appendix
0.655 0.345 0.000
T91.3 Sequelae of injury of spinal cord
0.654 0.346 0.000
T46.1 Calcium-channel blockers
0.654 0.346 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.654 0.346 0.000
Y43.3 Other antineoplastic drugs
0.654 0.346 0.000
S98 Traumatic amputation of ankle and foot
0.653 0.347 0.000
S97 Crushing injury of ankle and foot
0.653 0.347 0.000
S95 Injury of blood vessels at ankle and foot level
0.653 0.347 0.000
S94 Injury of nerves at ankle and foot level
0.653 0.347 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.652 0.347 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.653 0.347 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.651 0.349 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.651 0.349 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.649 0.351 0.000
T39.4 Antirheumatics, not elsewhere classified
0.649 0.351 0.000
T39.2 Pyrazolone derivatives
0.649 0.351 0.000
K11 Diseases of salivary glands
0.648 0.352 0.000
S92.1 Fracture of talus
0.648 0.352 0.000
T63 Toxic effect of contact with venomous animals
0.648 0.352 0.000
K36 Other appendicitis
0.647 0.353 0.000
K70.0 Alcoholic fatty liver
0.646 0.354 0.000
K14.0 Glossitis
0.645 0.355 0.000
I77 Other disorders of arteries and arterioles
0.645 0.355 0.000
R25 Abnormal involuntary movements
0.644 0.356 0.000
X78.0 Home
0.643 0.357 0.000
G25 Other extrapyramidal and movement disorders
0.643 0.357 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.643 0.357 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.642 0.358 0.000
R87.6 Abnormal cytological findings
0.642 0.358 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.641 0.358 0.000
M45-M49 Spondylopathies
0.641 0.359 0.000
I63 Cerebral infarction
0.641 0.359 0.000
S27.3 Other injuries of lung
0.641 0.359 0.000
T75 Effects of other external causes
0.640 0.360 0.000
T74 Maltreatment syndromes
0.640 0.360 0.000
T73 Effects of other deprivation
0.640 0.360 0.000
T70 Effects of air pressure and water pressure
0.640 0.360 0.000
T69 Other effects of reduced temperature
0.640 0.360 0.000
T67 Effects of heat and light
0.640 0.360 0.000
T71 Asphyxiation
0.640 0.360 0.000
T66 Unspecified effects of radiation
0.640 0.360 0.000
Y45.1 Salicylates
0.640 0.360 0.000
Y45.2 Propionic acid derivatives
0.639 0.361 0.000
D55-D59 Haemolytic anaemias
0.639 0.361 0.000
I46.1 Sudden cardiac death, so described
0.638 0.362 0.000
D73 Diseases of spleen
0.637 0.363 0.000
R46 Symptoms and signs involving appearance and behaviour
0.637 0.363 0.000
S27.2 Traumatic heamopneumothorax
0.637 0.363 0.000
M91-M94 Chondropathies
0.636 0.364 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.636 0.364 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.636 0.364 0.000
S06.2 Diffuse brain injury
0.636 0.364 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.364 0.000
K05 Gingivitis and periodontal diseases
0.636 0.364 0.000
W20-W49 Exposure to inanimate mechanical forces
0.636 0.364 0.000
D72 Other disorders of white blood cells
0.634 0.366 0.000
S27.1 Traumatic haemothorax
0.634 0.366 0.000
K70.4 Alcoholic hepatic failure
0.634 0.366 0.000
I95 Hypotension
0.634 0.366 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.634 0.366 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.633 0.366 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.633 0.367 0.000
Q35-Q37 Cleft lip and cleft palate
0.633 0.367 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.633 0.367 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.633 0.367 0.000
G51.3 Clonic hemifacial spasm
0.632 0.368 0.000
Y43.0 Antiallergic and antiemetic drugs
0.632 0.368 0.000
T45.5 Anticoagulants
0.632 0.368 0.000
I74 Arterial embolism and thrombosis
0.631 0.369 0.000
I50.0 Congestive heart failure
0.631 0.369 0.000
W13 Fall from, out of or through building or structure
0.630 0.370 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.630 0.370 0.000
Chapter I Certain infectious and parasitic diseases
0.630 0.370 0.000
S02.4 Fracture of malar and maxillary bones
0.629 0.371 0.000
S01.2 Open wound of nose
0.629 0.371 0.000
G59.0 Diabetic mononeuropathy
0.629 0.371 0.000
I65.2 Occlusion and stenosis of carotid artery
0.629 0.371 0.000
T65 Toxic effect of other and unspecified substances
0.628 0.371 0.000
T62 Toxic effect of other noxious substances eaten as food
0.628 0.371 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.628 0.371 0.000
T60 Toxic effect of pesticides
0.628 0.371 0.000
T57 Toxic effect of other inorganic substances
0.628 0.371 0.000
T56 Toxic effect of metals
0.628 0.371 0.000
T54 Toxic effect of corrosive substances
0.628 0.371 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.628 0.371 0.000
T52 Toxic effect of organic solvents
0.628 0.371 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.628 0.371 0.000
T58 Toxic effect of carbon monoxide
0.628 0.371 0.000
T55 Toxic effect of soaps and detergents
0.628 0.371 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.628 0.372 0.000
Y57.5 X-ray contrast media
0.627 0.373 0.000
S54.0 Injury of ulnar nerve at forearm level
0.627 0.373 0.000
S91 Open wound of ankle and foot
0.627 0.373 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.626 0.374 0.000
S06.8 Other intracranial injuries
0.625 0.375 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.624 0.375 0.000
T92 Sequelae of injuries of upper limb
0.624 0.376 0.000
I42.8 Other cardiomyopathies
0.624 0.376 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.624 0.376 0.000
I42.6 Alcoholic cardiomyopathy
0.624 0.376 0.000
I42.5 Other restrictive cardiomyopathy
0.624 0.376 0.000
I42.4 Endocardial fibroelastosis
0.624 0.376 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.624 0.376 0.000
S05.8 Other injuries of eye and orbit
0.624 0.376 0.000
S50.8 Other superficial injuries of forearm
0.623 0.377 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.623 0.377 0.000
G54 Nerve root and plexus disorders
0.622 0.377 0.000
T86.1 Kidney transplant failure and rejection
0.622 0.378 0.000
G30.9 Alzheimer's disease, unspecified
0.622 0.378 0.000
E20-E35 Disorders of other endocrine glands
0.622 0.378 0.000
R06 Abnormalities of breathing
0.621 0.379 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.620 0.379 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.620 0.380 0.000
I07 Rheumatic tricuspid valve diseases
0.620 0.380 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.619 0.381 0.000
G81.1 Spastic hemiplegia
0.619 0.381 0.000
G81.0 Flaccid hemiplegia
0.619 0.381 0.000
Chapter VIII Diseases of the ear and mastoid process
0.619 0.381 0.000
K03 Other diseases of hard tissues of teeth
0.618 0.382 0.000
K00 Disorders of tooth development and eruption
0.618 0.382 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.618 0.382 0.000
S26 Injury of heart
0.618 0.382 0.000
S25 Injury of blood vessels of thorax
0.618 0.382 0.000
S24 Injury of nerves and spinal cord at thorax level
0.618 0.382 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.618 0.382 0.000
S21 Open wound of thorax
0.618 0.382 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.618 0.382 0.000
R05 Cough
0.618 0.382 0.000
I30 Acute pericarditis
0.618 0.382 0.000
X84 Intentional self-harm by unspecified means
0.617 0.383 0.000
X83 Intentional self-harm by other specified means
0.617 0.383 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.617 0.383 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.617 0.383 0.000
X80 Intentional self-harm by jumping from a high place
0.617 0.383 0.000
X79 Intentional self-harm by blunt object
0.617 0.383 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.617 0.383 0.000
X76 Intentional self-harm by smoke, fire and flames
0.617 0.383 0.000
X75 Intentional self-harm by explosive material
0.617 0.383 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.617 0.383 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.617 0.383 0.000
X72 Intentional self-harm by handgun discharge
0.617 0.383 0.000
X71 Intentional self-harm by drowning and submersion
0.617 0.383 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.617 0.383 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.617 0.383 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.617 0.383 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.617 0.383 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.617 0.383 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.617 0.383 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.617 0.383 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.617 0.383 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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