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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77542162
log Bayes Factor = 16.8585
Chromosome 17   position 67,081,278  (GRCh37) Explore rs77542162 on Ensembl!
Variant rs77542162 is listed in the   GWAS Catalog   ⇪
Variant rs77542162 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.998 0.002 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.994 0.006 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.989 0.011 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
Z86 Personal history of certain other diseases
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
Z86.7 Personal history of diseases of the circulatory system
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.985 0.015 0.000
I26 Pulmonary embolism
0.982 0.018 0.000
I20 Angina pectoris
0.981 0.019 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.981 0.019 0.000
E78.5 Hyperlipidaemia, unspecified
0.977 0.023 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.977 0.023 0.000
S60-S69 Injuries to the wrist and hand
0.976 0.024 0.000
I80 Phlebitis and thrombophlebitis
0.976 0.024 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.974 0.026 0.000
I25.1 Atherosclerotic heart disease
0.970 0.030 0.000
Z95.1 Presence of aortocoronary bypass graft
0.969 0.031 0.000
M81 Osteoporosis without pathological fracture
0.963 0.037 0.000
I20.9 Angina pectoris, unspecified
0.962 0.038 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.960 0.040 0.000
S80-S89 Injuries to the knee and lower leg
0.956 0.044 0.000
M20.2 Hallux rigidus
0.951 0.049 0.000
M20.1 Hallux valgus (acquired)
0.950 0.050 0.000
I71 Aortic aneurysm and dissection
0.949 0.051 0.000
M81.9 Osteoporosis, unspecified
0.948 0.052 0.000
M20.4 Other hammer toe(s) (acquired)
0.945 0.055 0.000
S82 Fracture of lower leg, including ankle
0.939 0.061 0.000
I73 Other peripheral vascular diseases
0.939 0.061 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.938 0.062 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.934 0.066 0.000
I21 Acute myocardial infarction
0.928 0.072 0.000
Z83 Family history of other specific disorders
0.925 0.075 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.912 0.088 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.909 0.091 0.000
I73.9 Peripheral vascular disease, unspecified
0.907 0.093 0.000
M35 Other systemic involvement of connective tissue
0.906 0.094 0.000
I25.2 Old myocardial infarction
0.902 0.098 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.901 0.099 0.000
I21.9 Acute myocardial infarction, unspecified
0.898 0.102 0.000
I83 Varicose veins of lower extremities
0.898 0.102 0.000
S50-S59 Injuries to the elbow and forearm
0.896 0.104 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.896 0.104 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.893 0.107 0.000
S20-S29 Injuries to the thorax
0.893 0.107 0.000
Chapter VII Diseases of the eye and adnexa
0.882 0.118 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.882 0.118 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.879 0.121 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.871 0.129 0.000
S82.2 Fracture of shaft of tibia
0.867 0.133 0.000
S90-S99 Injuries to the ankle and foot
0.865 0.135 0.000
M65-M68 Disorders of synovium and tendon
0.861 0.139 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.860 0.140 0.000
Z29 Need for other prophylactic measures
0.857 0.143 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.856 0.144 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.852 0.148 0.000
I22 Subsequent myocardial infarction
0.850 0.149 0.000
M35.3 Polymyalgia rheumatica
0.849 0.151 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.849 0.151 0.000
S64 Injury of nerves at wrist and hand level
0.848 0.152 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.845 0.155 0.000
S82.0 Fracture of patella
0.837 0.162 0.000
Z83.7 Family history of diseases of the digestive system
0.830 0.170 0.000
M20.3 Other deformity of hallux (acquired)
0.829 0.171 0.000
Z87 Personal history of other diseases and conditions
0.827 0.173 0.000
S82.6 Fracture of lateral malleolus
0.823 0.177 0.000
M21 Other acquired deformities of limbs
0.822 0.178 0.000
S52 Fracture of forearm
0.821 0.179 0.000
H53-H54 Visual disturbances and blindness
0.818 0.182 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.816 0.184 0.000
M84 Disorders of continuity of bone
0.816 0.184 0.000
S40-S49 Injuries to the shoulder and upper arm
0.816 0.184 0.000
S82.20 Fracture of shaft of tibia (closed)
0.815 0.185 0.000
I77 Other disorders of arteries and arterioles
0.814 0.186 0.000
Chapter VIII Diseases of the ear and mastoid process
0.812 0.188 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.810 0.190 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.809 0.191 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.804 0.196 0.000
M05-M14 Inflammatory polyarthropathies
0.804 0.196 0.000
Z87.0 Personal history of diseases of the respiratory system
0.802 0.198 0.000
I81 Portal vein thrombosis
0.802 0.198 0.000
I20.1 Angina pectoris with documented spasm
0.802 0.198 0.000
I85 Oesophageal varices
0.796 0.204 0.000
I25.3 Aneurysm of heart
0.795 0.205 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.795 0.205 0.000
M25 Other joint disorders, not elsewhere classified
0.794 0.206 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.793 0.207 0.000
H40-H42 Glaucoma
0.789 0.211 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.788 0.212 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.787 0.213 0.000
I74 Arterial embolism and thrombosis
0.787 0.213 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.785 0.215 0.000
M85 Other disorders of bone density and structure
0.784 0.216 0.000
S62 Fracture at wrist and hand level
0.783 0.217 0.000
S70-S79 Injuries to the hip and thigh
0.781 0.219 0.000
S82.8 Fractures of other parts of lower leg
0.777 0.223 0.000
H53 Visual disturbances
0.776 0.224 0.000
I95 Hypotension
0.775 0.225 0.000
M45-M49 Spondylopathies
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.772 0.228 0.000
S65 Injury of blood vessels at wrist and hand level
0.772 0.228 0.000
M70-M79 Other soft tissue disorders
0.769 0.231 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.768 0.232 0.000
S52.5 Fracture of lower end of radius
0.766 0.234 0.000
S82.00 Fracture of patella (closed)
0.764 0.236 0.000
S00-S09 Injuries to the head
0.764 0.236 0.000
E78.8 Other disorders of lipoprotein metabolism
0.763 0.237 0.000
Z29.0 Isolation
0.762 0.238 0.000
I72 Other aneurysm
0.760 0.240 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.759 0.241 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.758 0.242 0.000
E88 Other metabolic disorders
0.757 0.243 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.756 0.244 0.000
M31 Other necrotising vasculopathies
0.755 0.245 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
I27 Other pulmonary heart diseases
0.752 0.248 0.000
Z83.5 Family history of eye and ear disorders
0.752 0.248 0.000
Z29.8 Other specified prophylactic measures
0.751 0.249 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.750 0.249 0.000
S69 Other and unspecified injuries of wrist and hand
0.750 0.250 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.746 0.254 0.000
M00-M03 Infectious arthropathies
0.746 0.254 0.000
M60-M63 Disorders of muscles
0.745 0.255 0.000
M86-M90 Other osteopathies
0.745 0.255 0.000
T93 Sequelae of injuries of lower limb
0.743 0.257 0.000
E00-E07 Disorders of thyroid gland
0.743 0.257 0.000
I82 Other venous embolism and thrombosis
0.742 0.258 0.000
M20.5 Other deformities of toe(s) (acquired)
0.740 0.260 0.000
S82.60 Fracture of lateral malleolus (closed)
0.739 0.261 0.000
I20.8 Other forms of angina pectoris
0.739 0.261 0.000
E40-E46 Malnutrition
0.738 0.262 0.000
H65-H75 Diseases of middle ear and mastoid
0.738 0.262 0.000
M91-M94 Chondropathies
0.737 0.263 0.000
M06 Other rheumatoid arthritis
0.737 0.263 0.000
I71.0 Dissection of aorta [any part]
0.733 0.267 0.000
S60 Superficial injury of wrist and hand
0.732 0.268 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.731 0.269 0.000
Z83.3 Family history of diabetes mellitus
0.730 0.270 0.000
I70 Atherosclerosis
0.729 0.270 0.000
S61 Open wound of wrist and hand
0.729 0.271 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.729 0.271 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.729 0.271 0.000
Z81 Family history of mental and behavioural disorders
0.726 0.274 0.000
T79-T79 Certain early complications of trauma
0.726 0.274 0.000
S92 Fracture of foot, except ankle
0.723 0.276 0.000
M24 Other specific joint derangements
0.722 0.278 0.000
H40 Glaucoma
0.722 0.278 0.000
Z82.3 Family history of stroke
0.721 0.279 0.000
I86 Varicose veins of other sites
0.720 0.280 0.000
S68 Traumatic amputation of wrist and hand
0.720 0.280 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I95.9 Hypotension, unspecified
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.716 0.284 0.000
E78.4 Other hyperlipidaemia
0.716 0.284 0.000
E78.3 Hyperchylomicronaemia
0.716 0.284 0.000
E78.1 Pure hyperglyceridaemia
0.716 0.284 0.000
Chapter I Certain infectious and parasitic diseases
0.715 0.285 0.000
H53.1 Subjective visual disturbances
0.714 0.286 0.000
S64.3 Injury of digital nerve of thumb
0.714 0.286 0.000
I88 Nonspecific lymphadenitis
0.714 0.286 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.714 0.286 0.000
S82.4 Fracture of fibula alone
0.713 0.287 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.287 0.000
M65 Synovitis and tenosynovitis
0.712 0.288 0.000
S27 Injury of other and unspecified intrathoracic organs
0.712 0.288 0.000
I99 Other and unspecified disorders of circulatory system
0.711 0.289 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.710 0.289 0.000
I28 Other diseases of pulmonary vessels
0.710 0.290 0.000
Z84 Family history of other conditions
0.709 0.291 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.709 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.292 0.000
M83 Adult osteomalacia
0.707 0.293 0.000
M82 Osteoporosis in diseases classified elsewhere
0.707 0.293 0.000
E85 Amyloidosis
0.706 0.294 0.000
E84 Cystic fibrosis
0.706 0.294 0.000
E79 Disorders of purine and pyrimidine metabolism
0.706 0.294 0.000
E77 Disorders of glycoprotein metabolism
0.706 0.294 0.000
E76 Disorders of glycosaminoglycan metabolism
0.706 0.294 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.706 0.294 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
E73 Lactose intolerance
0.706 0.294 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.294 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.706 0.294 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.294 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.706 0.294 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.704 0.296 0.000
E78.2 Mixed hyperlipidaemia
0.703 0.296 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.703 0.297 0.000
Z97 Presence of other devices
0.703 0.297 0.000
S22.0 Fracture of thoracic vertebra
0.702 0.298 0.000
S52.50 Fracture of lower end of radius (closed)
0.702 0.298 0.000
S67 Crushing injury of wrist and hand
0.700 0.300 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.700 0.300 0.000
Z93 Artificial opening status
0.700 0.300 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.700 0.300 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.700 0.300 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.698 0.302 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.698 0.302 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.698 0.302 0.000
Z82.2 Family history of deafness and hearing loss
0.698 0.302 0.000
Z82.1 Family history of blindness and visual loss
0.698 0.302 0.000
Z95.4 Presence of other heart-valve replacement
0.697 0.303 0.000
M80 Osteoporosis with pathological fracture
0.697 0.303 0.000
M67 Other disorders of synovium and tendon
0.697 0.303 0.000
T91 Sequelae of injuries of neck and trunk
0.696 0.304 0.000
H55-H59 Other disorders of eye and adnexa
0.695 0.305 0.000
T92 Sequelae of injuries of upper limb
0.695 0.305 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.694 0.306 0.000
Z95.2 Presence of prosthetic heart valve
0.694 0.306 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.694 0.306 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.694 0.306 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.693 0.307 0.000
I87 Other disorders of veins
0.691 0.309 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.691 0.309 0.000
M81.8 Other osteoporosis
0.691 0.309 0.000
M81.6 Localised osteoporosis [Lequesne]
0.691 0.309 0.000
M81.5 Idiopathic osteoporosis
0.691 0.309 0.000
M81.4 Drug-induced osteoporosis
0.691 0.309 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.691 0.309 0.000
M81.2 Osteoporosis of disuse
0.691 0.309 0.000
M81.1 Postoophorectomy osteoporosis
0.691 0.309 0.000
M81.0 Postmenopausal osteoporosis
0.691 0.309 0.000
M81.98 Osteoporosis, unspecified (Other)
0.690 0.310 0.000
S81 Open wound of lower leg
0.688 0.312 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.686 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.314 0.000
M79.6 Pain in limb
0.686 0.314 0.000
S88 Traumatic amputation of lower leg
0.685 0.315 0.000
S87 Crushing injury of lower leg
0.685 0.315 0.000
S86 Injury of muscle and tendon at lower leg level
0.685 0.315 0.000
S85 Injury of blood vessels at lower leg level
0.685 0.315 0.000
S84 Injury of nerves at lower leg level
0.685 0.315 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.684 0.316 0.000
S64.4 Injury of digital nerve of other finger
0.684 0.316 0.000
Q80-Q89 Other congenital malformations
0.684 0.316 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.682 0.318 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.681 0.319 0.000
T90 Sequelae of injuries of head
0.681 0.319 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.680 0.320 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.680 0.320 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.680 0.320 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.680 0.320 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.679 0.321 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.679 0.321 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.679 0.321 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.679 0.321 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.679 0.321 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.679 0.321 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.679 0.321 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.679 0.321 0.000
Z94 Transplanted organ and tissue status
0.677 0.323 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.675 0.325 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.675 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.674 0.326 0.000
S82.9 Fracture of lower leg, part unspecified
0.674 0.326 0.000
S82.7 Multiple fractures of lower leg
0.674 0.326 0.000
I73.8 Other specified peripheral vascular diseases
0.673 0.327 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.673 0.327 0.000
M22 Disorders of patella
0.671 0.329 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.670 0.330 0.000
E03 Other hypothyroidism
0.669 0.331 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.668 0.332 0.000
H53.2 Diplopia
0.667 0.333 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.665 0.335 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.665 0.335 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.663 0.337 0.000
Z83.6 Family history of diseases of the respiratory system
0.663 0.337 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.663 0.337 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.663 0.337 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.663 0.337 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.663 0.337 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.663 0.337 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.663 0.337 0.000
M25.7 Osteophyte
0.663 0.337 0.000
M06.9 Rheumatoid arthritis, unspecified
0.663 0.337 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.661 0.339 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.659 0.341 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.658 0.341 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.655 0.345 0.000
Q60-Q64 Congenital malformations of the urinary system
0.654 0.345 0.000
Z28 Immunisation not carried out
0.654 0.346 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.654 0.346 0.000
Z26 Need for immunisation against other single infectious diseases
0.654 0.346 0.000
Z25 Need for immunisation against other single viral diseases
0.654 0.346 0.000
Z24 Need for immunisation against certain single viral diseases
0.654 0.346 0.000
Z23 Need for immunisation against single bacterial diseases
0.654 0.346 0.000
Z20 Contact with and exposure to communicable diseases
0.654 0.346 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.654 0.346 0.000
Z22 Carrier of infectious disease
0.654 0.346 0.000
I60-I69 Cerebrovascular diseases
0.654 0.346 0.000
O80-O84 Delivery
0.653 0.347 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.652 0.347 0.000
M21.3 Wrist or foot drop (acquired)
0.650 0.349 0.000
Z89 Acquired absence of limb
0.650 0.349 0.000
I25.5 Ischaemic cardiomyopathy
0.650 0.350 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.650 0.350 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.649 0.351 0.000
M35.8 Other specified systemic involvement of connective tissue
0.649 0.351 0.000
M35.7 Hypermobility syndrome
0.649 0.351 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.649 0.351 0.000
M35.5 Multifocal fibrosclerosis
0.649 0.351 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.649 0.351 0.000
M35.2 Behcet's disease
0.649 0.351 0.000
M35.1 Other overlap syndromes
0.649 0.351 0.000
M40-M43 Deforming dorsopathies
0.649 0.351 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
H73 Other disorders of tympanic membrane
0.649 0.351 0.000
S99 Other and unspecified injuries of ankle and foot
0.648 0.352 0.000
S50 Superficial injury of forearm
0.647 0.353 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.644 0.356 0.000
I20.0 Unstable angina
0.643 0.357 0.000
S59 Other and unspecified injuries of forearm
0.642 0.357 0.000
S58 Traumatic amputation of forearm
0.642 0.357 0.000
S57 Crushing injury of forearm
0.642 0.357 0.000
S56 Injury of muscle and tendon at forearm level
0.642 0.357 0.000
S55 Injury of blood vessels at forearm level
0.642 0.357 0.000
S54 Injury of nerves at forearm level
0.642 0.357 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.642 0.357 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.642 0.358 0.000
S51 Open wound of forearm
0.641 0.359 0.000
S01 Open wound of head
0.641 0.359 0.000
T98 Sequelae of other and unspecified effects of external causes
0.640 0.360 0.000
T95 Sequelae of burns, corrosions and frostbite
0.640 0.360 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.640 0.360 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.640 0.360 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.640 0.360 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.640 0.360 0.000
S29 Other and unspecified injuries of thorax
0.640 0.360 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.640 0.360 0.000
S26 Injury of heart
0.640 0.360 0.000
S25 Injury of blood vessels of thorax
0.640 0.360 0.000
S24 Injury of nerves and spinal cord at thorax level
0.640 0.360 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.640 0.360 0.000
S21 Open wound of thorax
0.640 0.360 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.640 0.360 0.000
Chapter V Mental and behavioural disorders
0.639 0.361 0.000
M85.8 Other specified disorders of bone density and structure
0.639 0.361 0.000
B25-B34 Other viral diseases
0.638 0.362 0.000
S82.5 Fracture of medial malleolus
0.637 0.362 0.000
H71 Cholesteatoma of middle ear
0.637 0.363 0.000
S40 Superficial injury of shoulder and upper arm
0.636 0.364 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.635 0.365 0.000
M21.0 Valgus deformity, not elsewhere classified
0.635 0.365 0.000
S52.51 Fracture of lower end of radius (open)
0.633 0.367 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.632 0.367 0.000
S22.2 Fracture of sternum
0.631 0.369 0.000
M45 Ankylosing spondylitis
0.631 0.369 0.000
I21.4 Acute subendocardial myocardial infarction
0.631 0.369 0.000
T36 Poisoning by systemic antibiotics
0.628 0.372 0.000
S62.4 Multiple fractures of metacarpal bones
0.628 0.372 0.000
T66-T78 Other and unspecified effects of external causes
0.627 0.373 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.626 0.373 0.000
S65.5 Injury of blood vessel(s) of other finger
0.626 0.374 0.000
Z29.2 Other prophylactic chemotherapy
0.626 0.374 0.000
S89 Other and unspecified injuries of lower leg
0.625 0.375 0.000
E20-E35 Disorders of other endocrine glands
0.625 0.375 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.624 0.375 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.623 0.376 0.000
M84.0 Malunion of fracture
0.623 0.377 0.000
I77.6 Arteritis, unspecified
0.622 0.378 0.000
S79 Other and unspecified injuries of hip and thigh
0.622 0.378 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.622 0.378 0.000
S82.21 Fracture of shaft of tibia (open)
0.621 0.378 0.000
I85.0 Oesophageal varices with bleeding
0.621 0.379 0.000
E65-E68 Obesity and other hyperalimentation
0.621 0.379 0.000
S98 Traumatic amputation of ankle and foot
0.620 0.380 0.000
S97 Crushing injury of ankle and foot
0.620 0.380 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.620 0.380 0.000
S95 Injury of blood vessels at ankle and foot level
0.620 0.380 0.000
S94 Injury of nerves at ankle and foot level
0.620 0.380 0.000
S91 Open wound of ankle and foot
0.620 0.380 0.000
S90 Superficial injury of ankle and foot
0.620 0.380 0.000
O36 Maternal care for other known or suspected foetal problems
0.620 0.380 0.000
M77 Other enthesopathies
0.619 0.381 0.000
I27.2 Other secondary pulmonary hypertension
0.619 0.381 0.000
Z98 Other postsurgical states
0.618 0.382 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.617 0.383 0.000
M66 Spontaneous rupture of synovium and tendon
0.617 0.383 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.617 0.383 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.617 0.383 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.617 0.383 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.617 0.383 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.617 0.383 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.617 0.383 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.617 0.383 0.000
Z93.3 Colostomy status
0.616 0.384 0.000
E03.9 Hypothyroidism, unspecified
0.616 0.384 0.000
Z29.9 Prophylactic measure, unspecified
0.614 0.385 0.000
Z29.1 Prophylactic immunotherapy
0.614 0.385 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.614 0.385 0.000
S20 Superficial injury of thorax
0.614 0.386 0.000
Q50-Q56 Congenital malformations of genital organs
0.614 0.386 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.614 0.386 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.614 0.386 0.000
Q35-Q37 Cleft lip and cleft palate
0.614 0.386 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.614 0.386 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.614 0.386 0.000
I85.9 Oesophageal varices without bleeding
0.612 0.387 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.612 0.388 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.612 0.388 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.611 0.389 0.000
M25.9 Joint disorder, unspecified
0.611 0.389 0.000
S80 Superficial injury of lower leg
0.611 0.389 0.000
Z95.0 Presence of cardiac pacemaker
0.611 0.389 0.000
O85-O92 Complications predominantly related to the puerperium
0.610 0.389 0.000
I22.8 Subsequent myocardial infarction of other sites
0.610 0.390 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.610 0.390 0.000
S09 Other and unspecified injuries of head
0.610 0.390 0.000
I89.1 Lymphangitis
0.609 0.391 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.608 0.392 0.000
S64.8 Injury of other nerves at wrist and hand level
0.608 0.392 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.608 0.392 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.608 0.392 0.000
S64.1 Injury of median nerve at wrist and hand level
0.608 0.392 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.608 0.392 0.000
I73.0 Raynaud's syndrome
0.607 0.392 0.000
H40.1 Primary open-angle glaucoma
0.607 0.393 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.607 0.393 0.000
M21.1 Varus deformity, not elsewhere classified
0.607 0.393 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.606 0.394 0.000
S92.2 Fracture of other tarsal bone(s)
0.606 0.394 0.000
S82.1 Fracture of upper end of tibia
0.605 0.395 0.000
H10-H13 Disorders of conjunctiva
0.604 0.396 0.000
M11 Other crystal arthropathies
0.604 0.396 0.000
I95.2 Hypotension due to drugs
0.604 0.396 0.000
H40.2 Primary angle-closure glaucoma
0.603 0.397 0.000
T93.0 Sequelae of open wound of lower limb
0.603 0.397 0.000
H53.9 Visual disturbance, unspecified
0.603 0.397 0.000
H60-H62 Diseases of external ear
0.602 0.398 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.602 0.398 0.000
I89.0 Lymphoedema, not elsewhere classified
0.602 0.398 0.000
M05 Seropositive rheumatoid arthritis
0.601 0.398 0.000
Z95.3 Presence of xenogenic heart valve
0.601 0.399 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.601 0.399 0.000
S82.01 Fracture of patella (open)
0.600 0.399 0.000
H20 Iridocyclitis
0.600 0.400 0.000
M35.0 Sicca syndrome [Sjogren]
0.599 0.400 0.000
T93.2 Sequelae of other fractures of lower limb
0.599 0.401 0.000
M65.3 Trigger finger
0.598 0.402 0.000
H40.9 Glaucoma, unspecified
0.597 0.403 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.597 0.403 0.000
H53.4 Visual field defects
0.597 0.403 0.000
M79.66 Pain in limb (Lower leg)
0.597 0.403 0.000
S52.6 Fracture of lower end of both ulna and radius
0.596 0.404 0.000
M79.69 Pain in limb (Site unspecified)
0.596 0.404 0.000
S05 Injury of eye and orbit
0.596 0.404 0.000
I78 Diseases of capillaries
0.595 0.405 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.594 0.406 0.000
S82.3 Fracture of lower end of tibia
0.594 0.406 0.000
I72.3 Aneurysm of iliac artery
0.593 0.407 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.593 0.407 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.593 0.407 0.000
S72 Fracture of femur
0.593 0.407 0.000
H21 Other disorders of iris and ciliary body
0.593 0.407 0.000
Z80 Family history of malignant neoplasm
0.592 0.408 0.000
S62.6 Fracture of other finger
0.592 0.408 0.000
S82.61 Fracture of lateral malleolus (open)
0.590 0.410 0.000
S52.1 Fracture of upper end of radius
0.589 0.411 0.000
M21.9 Acquired deformity of limb, unspecified
0.589 0.411 0.000
M21.8 Other specified acquired deformities of limbs
0.589 0.411 0.000
M21.7 Unequal limb length (acquired)
0.589 0.411 0.000
M21.6 Other acquired deformities of ankle and foot
0.589 0.411 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.589 0.411 0.000
M21.4 Flat foot [pes planus] (acquired)
0.589 0.411 0.000
M21.2 Flexion deformity
0.589 0.411 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.589 0.411 0.000
S52.9 Fracture of forearm, part unspecified
0.588 0.411 0.000
S52.8 Fracture of other parts of forearm
0.588 0.411 0.000
S52.7 Multiple fractures of forearm
0.588 0.411 0.000
S52.4 Fracture of shafts of both ulna and radius
0.588 0.411 0.000
S52.3 Fracture of shaft of radius
0.588 0.411 0.000
S52.2 Fracture of shaft of ulna
0.588 0.411 0.000
S69.9 Unspecified injury of wrist and hand
0.587 0.413 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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