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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77620323
log Bayes Factor = 16.5538
Chromosome 2   position 198,625,141  (GRCh37) Explore rs77620323 on Ensembl!
Variant rs77620323 is part of Cluster X0118

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
E65-E68 Obesity and other hyperalimentation
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
E66 Obesity
0.997 0.003 0.000
E66.9 Obesity, unspecified
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
G40-G47 Episodic and paroxysmal disorders
0.994 0.006 0.000
I34 Nonrheumatic mitral valve disorders
0.993 0.007 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.992 0.008 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.991 0.009 0.000
G62 Other polyneuropathies
0.991 0.009 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.991 0.009 0.000
I34.0 Mitral (valve) insufficiency
0.989 0.011 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.989 0.011 0.000
T42.4 Benzodiazepines
0.983 0.017 0.000
G40 Epilepsy
0.983 0.017 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.982 0.018 0.000
E83 Disorders of mineral metabolism
0.981 0.019 0.000
G62.9 Polyneuropathy, unspecified
0.976 0.024 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.972 0.028 0.000
I47 Paroxysmal tachycardia
0.971 0.029 0.000
H02 Other disorders of eyelid
0.970 0.030 0.000
E11 Non-insulin-dependent diabetes mellitus
0.967 0.033 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.966 0.034 0.000
G40.9 Epilepsy, unspecified
0.963 0.037 0.000
I74 Arterial embolism and thrombosis
0.960 0.040 0.000
H16 Keratitis
0.939 0.061 0.000
E83.5 Disorders of calcium metabolism
0.939 0.061 0.000
S90-S99 Injuries to the ankle and foot
0.936 0.064 0.000
E10 Insulin-dependent diabetes mellitus
0.935 0.065 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.933 0.067 0.000
S10-S19 Injuries to the neck
0.932 0.068 0.000
I47.1 Supraventricular tachycardia
0.930 0.070 0.000
I78 Diseases of capillaries
0.930 0.070 0.000
Chapter VIII Diseases of the ear and mastoid process
0.928 0.072 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.925 0.075 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.923 0.077 0.000
E78.0 Pure hypercholesterolaemia
0.918 0.082 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.917 0.083 0.000
H55-H59 Other disorders of eye and adnexa
0.916 0.084 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.912 0.088 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.908 0.092 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.908 0.092 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.906 0.094 0.000
H21 Other disorders of iris and ciliary body
0.901 0.099 0.000
E11.9 Without complications
0.899 0.101 0.000
E11.5 With peripheral circulatory complications
0.897 0.103 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.897 0.103 0.000
I70 Atherosclerosis
0.896 0.104 0.000
E78.2 Mixed hyperlipidaemia
0.893 0.107 0.000
Chapter V Mental and behavioural disorders
0.893 0.107 0.000
I77 Other disorders of arteries and arterioles
0.892 0.108 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.891 0.109 0.000
I78.1 Naevus, nonneoplastic
0.888 0.112 0.000
H02.9 Disorder of eyelid, unspecified
0.885 0.115 0.000
E83.1 Disorders of iron metabolism
0.880 0.120 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.880 0.120 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.879 0.121 0.000
H53-H54 Visual disturbances and blindness
0.879 0.121 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.878 0.122 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.878 0.122 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.878 0.122 0.000
E78.8 Other disorders of lipoprotein metabolism
0.877 0.123 0.000
X60-X84 Intentional self-harm
0.877 0.123 0.000
I73 Other peripheral vascular diseases
0.876 0.124 0.000
S20-S29 Injuries to the thorax
0.873 0.127 0.000
E83.4 Disorders of magnesium metabolism
0.873 0.127 0.000
E10.3 With ophthalmic complications
0.872 0.128 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.870 0.130 0.000
H20 Iridocyclitis
0.870 0.130 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.870 0.130 0.000
G47 Sleep disorders
0.868 0.132 0.000
G62.8 Other specified polyneuropathies
0.867 0.133 0.000
I42 Cardiomyopathy
0.867 0.133 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.866 0.134 0.000
I45 Other conduction disorders
0.863 0.137 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.863 0.137 0.000
I80 Phlebitis and thrombophlebitis
0.863 0.137 0.000
H02.4 Ptosis of eyelid
0.863 0.137 0.000
S12 Fracture of neck
0.862 0.138 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.862 0.138 0.000
G63.2 Diabetic polyneuropathy
0.860 0.140 0.000
W20-W49 Exposure to inanimate mechanical forces
0.857 0.143 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.856 0.144 0.000
F30-F39 Mood [affective] disorders
0.855 0.145 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.855 0.145 0.000
H02.5 Other disorders affecting eyelid function
0.853 0.147 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.852 0.148 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.852 0.148 0.000
T51 Toxic effect of alcohol
0.848 0.152 0.000
H16.9 Keratitis, unspecified
0.846 0.154 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.843 0.157 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.843 0.157 0.000
H55 Nystagmus and other irregular eye movements
0.842 0.158 0.000
Y44 Agents primarily affecting blood constituents
0.842 0.158 0.000
I73.9 Peripheral vascular disease, unspecified
0.842 0.158 0.000
X20-X29 Contact with venomous animals and plants
0.839 0.161 0.000
G40.8 Other epilepsy
0.835 0.165 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.835 0.165 0.000
Y60.0 During surgical operation
0.830 0.170 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.829 0.171 0.000
H16.0 Corneal ulcer
0.829 0.171 0.000
H53 Visual disturbances
0.827 0.173 0.000
E10.4 With neurological complications
0.826 0.174 0.000
E11.2 With renal complications
0.826 0.174 0.000
V10-V19 Pedal cyclist injured in transport accident
0.823 0.177 0.000
F33 Recurrent depressive disorder
0.821 0.179 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.821 0.179 0.000
E88 Other metabolic disorders
0.820 0.180 0.000
G43 Migraine
0.820 0.180 0.000
I47.2 Ventricular tachycardia
0.818 0.182 0.000
S92 Fracture of foot, except ankle
0.817 0.183 0.000
I77.1 Stricture of artery
0.816 0.184 0.000
I49 Other cardiac arrhythmias
0.814 0.186 0.000
E78.5 Hyperlipidaemia, unspecified
0.814 0.186 0.000
H80-H83 Diseases of inner ear
0.813 0.187 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.810 0.190 0.000
H21.8 Other specified disorders of iris and ciliary body
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.809 0.191 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.807 0.193 0.000
Y00-Y09 Assault
0.802 0.198 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.799 0.201 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.798 0.202 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.797 0.203 0.000
T39.0 Salicylates
0.796 0.204 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.796 0.204 0.000
Y44.2 Anticoagulants
0.796 0.204 0.000
G62.1 Alcoholic polyneuropathy
0.795 0.205 0.000
I26 Pulmonary embolism
0.794 0.206 0.000
G83 Other paralytic syndromes
0.794 0.206 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.792 0.208 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.791 0.209 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.791 0.209 0.000
B50-B64 Protozoal diseases
0.791 0.209 0.000
T51.0 Ethanol
0.789 0.211 0.000
G40.5 Special epileptic syndromes
0.788 0.212 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.788 0.212 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.787 0.213 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.785 0.214 0.000
H18 Other disorders of cornea
0.784 0.216 0.000
I45.1 Other and unspecified right bundle-branch block
0.782 0.218 0.000
E13 Other specified diabetes mellitus
0.781 0.219 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.779 0.221 0.000
I10-I15 Hypertensive diseases
0.778 0.222 0.000
Chapter XXII Codes for special purposes
0.778 0.222 0.000
H02.3 Blepharochalasis
0.778 0.222 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.778 0.222 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.778 0.222 0.000
H15 Disorders of sclera
0.776 0.224 0.000
H90-H95 Other disorders of ear
0.775 0.225 0.000
T79-T79 Certain early complications of trauma
0.775 0.225 0.000
H02.0 Entropion and trichiasis of eyelid
0.772 0.228 0.000
T63 Toxic effect of contact with venomous animals
0.771 0.229 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.771 0.229 0.000
G47.9 Sleep disorder, unspecified
0.771 0.229 0.000
H57 Other disorders of eye and adnexa
0.768 0.232 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.766 0.234 0.000
I42.8 Other cardiomyopathies
0.764 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.764 0.236 0.000
I35 Nonrheumatic aortic valve disorders
0.764 0.236 0.000
G41 Status epilepticus
0.763 0.237 0.000
S14 Injury of nerves and spinal cord at neck level
0.762 0.238 0.000
E73 Lactose intolerance
0.761 0.238 0.000
H60-H62 Diseases of external ear
0.760 0.240 0.000
G11 Hereditary ataxia
0.758 0.242 0.000
I36 Nonrheumatic tricuspid valve disorders
0.757 0.243 0.000
F33.9 Recurrent depressive disorder, unspecified
0.755 0.245 0.000
T39.1 4-Aminophenol derivatives
0.755 0.245 0.000
E65 Localised adiposity
0.754 0.246 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.754 0.246 0.000
F43 Reaction to severe stress, and adjustment disorders
0.754 0.246 0.000
A80-A89 Viral infections of the central nervous system
0.753 0.247 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.753 0.247 0.000
I42.6 Alcoholic cardiomyopathy
0.752 0.248 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.752 0.248 0.000
I27 Other pulmonary heart diseases
0.751 0.249 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.751 0.249 0.000
H02.6 Xanthelasma of eyelid
0.750 0.250 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.748 0.252 0.000
H01 Other inflammation of eyelid
0.748 0.252 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.748 0.252 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.748 0.252 0.000
S91 Open wound of ankle and foot
0.748 0.252 0.000
H53.2 Diplopia
0.748 0.252 0.000
S12.1 Fracture of second cervical vertebra
0.747 0.253 0.000
I50 Heart failure
0.746 0.254 0.000
H04 Disorders of lachrymal system
0.744 0.256 0.000
H81 Disorders of vestibular function
0.744 0.256 0.000
E78.4 Other hyperlipidaemia
0.744 0.256 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.743 0.257 0.000
S12.2 Fracture of other specified cervical vertebra
0.743 0.257 0.000
H02.2 Lagophthalmos
0.742 0.258 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.742 0.258 0.000
S99 Other and unspecified injuries of ankle and foot
0.742 0.258 0.000
B65-B83 Helminthiases
0.740 0.260 0.000
E10.0 With coma
0.738 0.262 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.736 0.263 0.000
E11.6 With other specified complications
0.736 0.264 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.736 0.264 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.736 0.264 0.000
I34.1 Mitral (valve) prolapse
0.734 0.266 0.000
G61 Inflammatory polyneuropathy
0.733 0.267 0.000
F42 Obsessive-compulsive disorder
0.731 0.269 0.000
T42.1 Iminostilbenes
0.731 0.269 0.000
G47.3 Sleep apnoea
0.731 0.269 0.000
E10.1 With ketoacidosis
0.729 0.271 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.729 0.271 0.000
E66.0 Obesity due to excess calories
0.728 0.272 0.000
G60 Hereditary and idiopathic neuropathy
0.728 0.272 0.000
W50-W64 Exposure to animate mechanical forces
0.728 0.272 0.000
H53.8 Other visual disturbances
0.728 0.272 0.000
X23 Contact with hornets, wasps and bees
0.727 0.273 0.000
E40-E46 Malnutrition
0.726 0.274 0.000
E20-E35 Disorders of other endocrine glands
0.725 0.275 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.722 0.278 0.000
X41.9 Unspecified place
0.722 0.278 0.000
I05-I09 Chronic rheumatic heart diseases
0.720 0.280 0.000
E78.1 Pure hyperglyceridaemia
0.720 0.280 0.000
W44 Foreign body entering into or through eye or natural orifice
0.718 0.282 0.000
H43-H45 Disorders of vitreous body and globe
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
E67 Other hyperalimentation
0.716 0.284 0.000
E68 Sequelae of hyperalimentation
0.716 0.284 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.716 0.284 0.000
G64 Other disorders of peripheral nervous system
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
E66.1 Drug-induced obesity
0.715 0.285 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.713 0.287 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.712 0.288 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.712 0.288 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.712 0.288 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.712 0.288 0.000
E11.0 With coma
0.712 0.288 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.711 0.289 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.711 0.289 0.000
G00 Bacterial meningitis, not elsewhere classified
0.711 0.289 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
E78.6 Lipoprotein deficiency
0.710 0.289 0.000
E78.3 Hyperchylomicronaemia
0.710 0.289 0.000
G62.2 Polyneuropathy due to other toxic agents
0.710 0.289 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.710 0.290 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.710 0.290 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.710 0.290 0.000
T42.3 Barbiturates
0.710 0.290 0.000
T42.2 Succinimides and oxazolidinediones
0.710 0.290 0.000
T42.0 Hydantoin derivatives
0.710 0.290 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.710 0.290 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.709 0.291 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.709 0.291 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.709 0.291 0.000
G62.0 Drug-induced polyneuropathy
0.709 0.291 0.000
E11.4 With neurological complications
0.709 0.291 0.000
I42.9 Cardiomyopathy, unspecified
0.708 0.292 0.000
H20.0 Acute and subacute iridocyclitis
0.708 0.292 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.707 0.293 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.707 0.293 0.000
I35.1 Aortic (valve) insufficiency
0.706 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
T59 Toxic effect of other gases, fumes and vapours
0.705 0.295 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.705 0.295 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.704 0.295 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.704 0.295 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.704 0.295 0.000
I77.8 Other specified disorders of arteries and arterioles
0.704 0.296 0.000
W22 Striking against or struck by other objects
0.704 0.296 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.703 0.297 0.000
E83.8 Other disorders of mineral metabolism
0.703 0.297 0.000
E83.2 Disorders of zinc metabolism
0.703 0.297 0.000
E83.0 Disorders of copper metabolism
0.703 0.297 0.000
T18 Foreign body in alimentary tract
0.703 0.297 0.000
H92 Otalgia and effusion of ear
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.702 0.297 0.000
I89.0 Lymphoedema, not elsewhere classified
0.702 0.298 0.000
I49.9 Cardiac arrhythmia, unspecified
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
S29 Other and unspecified injuries of thorax
0.699 0.301 0.000
H20.1 Chronic iridocyclitis
0.699 0.301 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.699 0.301 0.000
G83.4 Cauda equina syndrome
0.698 0.302 0.000
G12 Spinal muscular atrophy and related syndromes
0.697 0.303 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.696 0.304 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.696 0.304 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.696 0.304 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.695 0.305 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.695 0.305 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.695 0.305 0.000
E11.7 With multiple complications
0.694 0.306 0.000
F34 Persistent mood [affective] disorders
0.693 0.307 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.693 0.307 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.693 0.307 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.693 0.307 0.000
I28 Other diseases of pulmonary vessels
0.692 0.308 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.692 0.308 0.000
S20 Superficial injury of thorax
0.691 0.309 0.000
E85 Amyloidosis
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.689 0.311 0.000
I47.0 Reentry ventricular arrhythmia
0.689 0.311 0.000
I74.8 Embolism and thrombosis of other arteries
0.689 0.311 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.689 0.311 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.689 0.311 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.689 0.311 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.688 0.311 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.688 0.312 0.000
H17 Corneal scars and opacities
0.688 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.688 0.312 0.000
Y65 Other misadventures during surgical and medical care
0.687 0.313 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.687 0.313 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.314 0.000
I77.0 Arteriovenous fistula, acquired
0.685 0.315 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.685 0.315 0.000
I12 Hypertensive renal disease
0.684 0.316 0.000
T91 Sequelae of injuries of neck and trunk
0.683 0.316 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.683 0.317 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.683 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.318 0.000
H81.1 Benign paroxysmal vertigo
0.681 0.319 0.000
B99-B99 Other infectious diseases
0.681 0.319 0.000
I30 Acute pericarditis
0.680 0.320 0.000
H53.0 Amblyopia ex anopsia
0.679 0.321 0.000
S90 Superficial injury of ankle and foot
0.678 0.322 0.000
E11.8 With unspecified complications
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.323 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
Q24 Other congenital malformations of heart
0.676 0.324 0.000
V40-V49 Car occupant injured in transport accident
0.676 0.324 0.000
X45 Accidental poisoning by and exposure to alcohol
0.675 0.325 0.000
H16.8 Other keratitis
0.673 0.327 0.000
H16.4 Corneal neovascularisation
0.673 0.327 0.000
H16.3 Interstitial and deep keratitis
0.673 0.327 0.000
H16.2 Keratoconjunctivitis
0.673 0.327 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.673 0.327 0.000
G03 Meningitis due to other and unspecified causes
0.672 0.328 0.000
S98 Traumatic amputation of ankle and foot
0.671 0.329 0.000
S97 Crushing injury of ankle and foot
0.671 0.329 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.671 0.329 0.000
S95 Injury of blood vessels at ankle and foot level
0.671 0.329 0.000
S94 Injury of nerves at ankle and foot level
0.671 0.329 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.671 0.329 0.000
E10.8 With unspecified complications
0.671 0.329 0.000
E10.7 With multiple complications
0.671 0.329 0.000
E10.6 With other specified complications
0.671 0.329 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.670 0.330 0.000
T65 Toxic effect of other and unspecified substances
0.669 0.331 0.000
T62 Toxic effect of other noxious substances eaten as food
0.669 0.331 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.669 0.331 0.000
T60 Toxic effect of pesticides
0.669 0.331 0.000
T57 Toxic effect of other inorganic substances
0.669 0.331 0.000
T56 Toxic effect of metals
0.669 0.331 0.000
T54 Toxic effect of corrosive substances
0.669 0.331 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.669 0.331 0.000
T52 Toxic effect of organic solvents
0.669 0.331 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.669 0.331 0.000
T55 Toxic effect of soaps and detergents
0.669 0.331 0.000
S10 Superficial injury of neck
0.669 0.331 0.000
S17 Crushing injury of neck
0.668 0.331 0.000
S15 Injury of blood vessels at neck level
0.668 0.331 0.000
S11 Open wound of neck
0.668 0.331 0.000
S18 Traumatic amputation at neck level
0.668 0.331 0.000
S16 Injury of muscle and tendon at neck level
0.668 0.331 0.000
I87 Other disorders of veins
0.667 0.333 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.667 0.333 0.000
B35-B49 Mycoses
0.667 0.333 0.000
I78.9 Disease of capillaries, unspecified
0.666 0.333 0.000
I78.8 Other diseases of capillaries
0.666 0.333 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.666 0.334 0.000
H20.9 Iridocyclitis, unspecified
0.666 0.334 0.000
I37 Pulmonary valve disorders
0.666 0.334 0.000
F40 Phobic anxiety disorders
0.665 0.335 0.000
S12.10 Fracture of second cervical vertebra (closed)
0.664 0.336 0.000
I45.3 Trifascicular block
0.664 0.336 0.000
X78 Intentional self-harm by sharp object
0.664 0.336 0.000
Y04 Assault by bodily force
0.664 0.336 0.000
I45.9 Conduction disorder, unspecified
0.664 0.336 0.000
Y64 Contaminated medical or biological substances
0.663 0.337 0.000
Y63 Failure in dosage during surgical and medical care
0.663 0.337 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.663 0.337 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.663 0.337 0.000
Y69 Unspecified misadventure during surgical and medical care
0.663 0.337 0.000
Y66 Nonadministration of surgical and medical care
0.663 0.337 0.000
T16 Foreign body in ear
0.662 0.338 0.000
I77.6 Arteritis, unspecified
0.662 0.338 0.000
F31 Bipolar affective disorder
0.661 0.339 0.000
I82 Other venous embolism and thrombosis
0.661 0.339 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.661 0.339 0.000
G82 Paraplegia and tetraplegia
0.659 0.341 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.659 0.341 0.000
T66-T78 Other and unspecified effects of external causes
0.658 0.342 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.658 0.342 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.658 0.342 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.658 0.342 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.658 0.342 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.658 0.342 0.000
G63.1 Polyneuropathy in neoplastic disease
0.658 0.342 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.658 0.342 0.000
S12.20 Fracture of other specified cervical vertebra (closed)
0.658 0.342 0.000
T58 Toxic effect of carbon monoxide
0.657 0.342 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.657 0.343 0.000
I72 Other aneurysm
0.655 0.345 0.000
T63.4 Venom of other arthropods
0.655 0.345 0.000
I31 Other diseases of pericardium
0.654 0.346 0.000
I49.1 Atrial premature depolarisation
0.654 0.346 0.000
S92.7 Multiple fractures of foot
0.653 0.347 0.000
T43.2 Other and unspecified antidepressants
0.651 0.349 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.651 0.349 0.000
T39.4 Antirheumatics, not elsewhere classified
0.651 0.349 0.000
T39.2 Pyrazolone derivatives
0.651 0.349 0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.651 0.349 0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.651 0.349 0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.651 0.349 0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.651 0.349 0.000
I33 Acute and subacute endocarditis
0.651 0.349 0.000
G43.8 Other migraine
0.651 0.349 0.000
I27.2 Other secondary pulmonary hypertension
0.650 0.350 0.000
V20-V29 Motorcycle rider injured in transport accident
0.649 0.350 0.000
Y59 Other and unspecified vaccines and biological substances
0.649 0.351 0.000
Y58 Bacterial vaccines
0.649 0.351 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.649 0.351 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.649 0.351 0.000
I85 Oesophageal varices
0.649 0.351 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.649 0.351 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.648 0.352 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.647 0.353 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.646 0.354 0.000
H21.4 Pupillary membranes
0.646 0.354 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.646 0.354 0.000
H21.2 Degeneration of iris and ciliary body
0.646 0.354 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.646 0.354 0.000
H21.0 Hyphaema
0.646 0.354 0.000
E10.2 With renal complications
0.645 0.355 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.645 0.355 0.000
Q21 Congenital malformations of cardiac septa
0.645 0.355 0.000
S92.0 Fracture of calcaneus
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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